Nucleosides - RNA / BOC Sciences

5'-DMT-2'-TBDMS-N6-Me-rA

Description: 5'-DMT-2'-TBDMS-N6-Me-rA is an extraordinary modified RNA nucleoside, allowing for unrivaled applications in the intricate domain of drug research and development, explicitly targeting RNA-based ailments encompassing malignant neoplasms, viral afflictions is as well as hereditary anomalies.

CAT: BRP-01808

CAS: 588698-75-3

MF: C38H47N5O6Si

MF: 697.91

Purity: ≥98% by HPLC

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Density: 1.21±0.1 g/cm3

Boiling Point: 797.8±70.0 °C at 760 mmHg

InChIKey: KEEBYCOQGORZDK-QGGAYTEESA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=NC3=C(N=CN=C32)NC)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: (2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-[6-(methylamino)purin-9-yl]oxolan-3-ol

InChI: InChI=1S/C38H47N5O6Si/c1-37(2,3)50(7,8)49-33-32(44)30(48-36(33)43-24-42-31-34(39-4)40-23-41-35(31)43)22-47-38(25-12-10-9-11-13-25,26-14-18-28(45-5)19-15-26)27-16-20-29(46-6)21-17-27/h9-21,23-24,30,32-33,36,44H,22H2,1-8H3,(H,39,40,41)/t30-,32-,33-,36-/m1/s1

Synonyms: 2'-O-(tert-butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-N6-methyladenosine; N6-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-t-butyldimethylsilyladenosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]-N-methyladenosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-methyladenosine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-dimethyl(tert-butyl)silyl-N6-methyladenosine

5'-O-DMT-2'-O-TBDMS-Inosine

Description: 5'-O-DMT-2'-O-TBDMS-Inosine is a modified nucleoside used in the synthesis of deoxyribonucleic acid or nucleic acid.

CAT: BRP-01809

CAS: 127212-34-4

MF: C37H44N4O7Si

MF: 684.85

Purity: ≥98% by HPLC

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Density: 1.24±0.1 g/cm3 (Predicted)

Boiling Point: 831.1±65.0°C (Predicted)

InChIKey: OPTOBSYBLQDPQN-QSYCCZFCSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=NC3=C2N=CNC3=O)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: 9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-9H-purin-6-ol

InChI: InChI=1S/C37H44N4O7Si/c1-36(2,3)49(6,7)48-32-31(42)29(47-35(32)41-23-40-30-33(41)38-22-39-34(30)43)21-46-37(24-11-9-8-10-12-24,25-13-17-27(44-4)18-14-25)26-15-19-28(45-5)20-16-26/h8-20,22-23,29,31-32,35,42H,21H2,1-7H3,(H,38,39,43)/t29-,31-,32-,35-/m1/s1

Synonyms: 5'-DMT-2'-tBDSilyl Inosine; 5'-DMT-2'-TBDMS-rI; Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one; 2'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)inosine

N-Benzoyl-5'-O-tritylcytidine

Description: N-Benzoyl-5'-O-tritylcytidine, a nucleoside analogue, has garnered interest in the development of antiviral agents targeting RNA viruses like hepatitis C and HIV. Its potential in the treatment of solid tumors including lung and breast cancer has also been observed. Moreover, this compound's structural attributes make it a valuable asset in the synthesis of modified nucleosides for a slew of biomedical uses.

CAT: BRP-01810

CAS: 41092-41-5

MF: C35H31N3O6

MF: 589.65

Purity: ≥98% by HPLC

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Density: 1.30±0.1 g/cm3 (Predicted)

InChIKey: VPHGCMRVEOZXRC-CSEBVFCESA-N

CanonicalSMILES: C1=CC=C(C=C1)C(=O)NC2=NC(=O)N(C=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)O)O

IUPAC Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(trityloxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C35H31N3O6/c39-30-28(44-33(31(30)40)38-22-21-29(37-34(38)42)36-32(41)24-13-5-1-6-14-24)23-43-35(25-15-7-2-8-16-25,26-17-9-3-10-18-26)27-19-11-4-12-20-27/h1-22,28,30-31,33,39-40H,23H2,(H,36,37,41,42)/t28-,30-,31-,33-/m1/s1

Synonyms: 5'-Trt-N4-Bz-rC; N-Benzoyl-5'-O-(triphenylmethyl)-Cytidine; 5'-O-trityl-4-N-benzoylcytidine; 5'-O-Trt-N4-Bz-rC; Cytidine, N-benzoyl-5'-O-(triphenylmethyl)-; N6-Benzoyl-5'-O-tritylcytidine

N-Acetyl-5'-O-tritylcytidine

Description: N-Acetyl-5'-O-tritylcytidine, a nucleoside analog commonly utilized in antiviral research, boasts potential as an agent to tackle various viral diseases, such as hepatitis B and C. Its selective inhibition of viral DNA synthesis is sparking interest in possible future drug development, and serves as a subject of study to further investigate antiviral drug efficacy and mechanisms of action.

CAT: BRP-01811

CAS: 31085-52-6

MF: C30H29N3O6

MF: 527.58

Purity: ≥98% by HPLC

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Density: 1.32±0.1 g/cm3

InChIKey: VJLDBTRYQIPAQK-YULOIDQLSA-N

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)O)O

IUPAC Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(trityloxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C30H29N3O6/c1-20(34)31-25-17-18-33(29(37)32-25)28-27(36)26(35)24(39-28)19-38-30(21-11-5-2-6-12-21,22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-18,24,26-28,35-36H,19H2,1H3,(H,31,32,34,37)/t24-,26-,27-,28-/m1/s1

Synonyms: 5'-Trt-N4-Ac-rC; 5'-O-Trt-N4-Ac-rC; N-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide; N-Acetyl-5'-O-(triphenylmethyl)cytidine; Acetamide, N-[1,2-dihydro-2-oxo-1-(5-O-trityl-β-D-ribofuranosyl)-4-pyrimidinyl]-

5'-tert-Butyldimethylsilyloxy-N4-acetyl-5-iodo-cytidine

Description: 5'-tert-butyldimethylsilyloxy-N4-acetyl-5-iodo-cytidine, a pharmaceutical intermediate renowned for its antiviral properties, is widely employed in the production of antiviral drugs. Its efficacy has been empirically proven against herpes simplex virus, cytomegalovirus, and varicella-zoster virus. Additionally, this product serves as a potent weapon in the biomedical industry's battle against numerous other viral infections that threaten public health.

CAT: BRP-01812

MF: C17H28IN3O6Si

MF: 525.42

Purity: ≥97% by HPLC

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InChIKey: FKZFVKBOIWTSKS-RGCMKSIDSA-N

IUPAC Name: N-(1-((2R,3R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-5-iodo-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

InChI: InChI=1S/C17H28IN3O6Si/c1-9(22)19-14-10(18)7-21(16(25)20-14)15-13(24)12(23)11(27-15)8-26-28(5,6)17(2,3)4/h7,11-13,15,23-24H,8H2,1-6H3,(H,19,20,22,25)/t11-,12-,13-,15-/m1/s1

Synonyms: 5'-O-TBDMS-N4-acetyl-5-iodo-cytidine

N-Benzoyl-5'-O-trityladenosine

Description: N-Benzoyl-5'-O-trityladenosine, a chemical compound frequently utilized as an intermediate in pharmaceutical synthesis, is well known for its antitumor, antiviral, and anti-inflammatory properties. Its rendering abilities facilitate the propagation of biorelevant molecules such as acyclovir and ganciclovir and construction of nucleoside analogs vital in the management of cancer and other viral illnesses.

CAT: BRP-01813

CAS: 18404-90-5

MF: C36H31N5O5

MF: 613.67

Purity: ≥98% by HPLC

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Density: 1.36±0.1 g/cm3

InChIKey: CLQLOYVVKMWBIY-JYYIKNSZSA-N

CanonicalSMILES: C1=CC=C(C=C1)C(=O)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)COC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(trityloxymethyl)oxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C36H31N5O5/c42-30-28(21-45-36(25-15-7-2-8-16-25,26-17-9-3-10-18-26)27-19-11-4-12-20-27)46-35(31(30)43)41-23-39-29-32(37-22-38-33(29)41)40-34(44)24-13-5-1-6-14-24/h1-20,22-23,28,30-31,35,42-43H,21H2,(H,37,38,40,44)/t28-,30-,31-,35-/m1/s1

Synonyms: 5'-Trt-N6-Bz-rA; N-Benzoyl-5'-O-(triphenylmethyl)-Adenosine; 5'-O-Trt-N6-Bz-rA; Adenosine, N-benzoyl-5'-O-(triphenylmethyl)-; Benzamide, N-[9-(5-O-trityl-β-D-ribofuranosyl)-9H-purin-6-yl]-; N-Benzoyl-5'-O-(triphenylmethyl)adenosine; 5'-O-Trityl-N6-benzoyladenosine

5'-O-Trityl Uridine

Description: 5'-O-Trityl Uridine, a paramount compound extensively employed in the biomedical domain, demonstrates outstanding prowess in the orchestration of RNA molecule research and development. This remarkable entity assumes the vital responsibility of safeguarding uridine throughout chemical reactions, thus enabling the discriminatory alteration of alternative functional groups. Remarkably adaptable, this multifaceted compound showcases unbounded utility in advancing RNA-centric therapeutics and facilitating comprehensive investigations into the intricate intricacies of RNA's overarching structure and intrinsic functioning.

CAT: BRP-01814

CAS: 6554-10-5

MF: C28H26N2O6

MF: 486.52

Purity: ≥98% by HPLC

Appearance: White Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.355±0.06 g/cm3

Melting Point: 207-208 °C

InChIKey: YQHCGMPQZCIQPS-VNSJUHMKSA-N

Solubility: Soluble in Dichloromethane, Ethanol, Methanol

CanonicalSMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C28H26N2O6/c31-23-16-17-30(27(34)29-23)26-25(33)24(32)22(36-26)18-35-28(19-10-4-1-5-11-19,20-12-6-2-7-13-20)21-14-8-3-9-15-21/h1-17,22,24-26,32-33H,18H2,(H,29,31,34)/t22-,24-,25-,26-/m1/s1

Synonyms: 5'-Trt-dU; 5'-O-Trityluridine; 5'-O-Triphenylmethyluridine; NSC 97038; 5'-O-Trityl-D-uridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

5'-Trt-N2-ibu-rG

Description: 5'-Trt-N2-ibu-rG, a nucleoside analog, exhibits strong potential as an effective anticancer agent, as it has been demonstrated to impede the growth and spread of certain cancer cell types, including leukemia and breast cancer. The mechanism behind its tumor suppression lies in its specific targeting of the RNA polymerase II enzyme, a key factor in the transcription of cancer-promoting genes, thus providing a promising avenue for chemotherapy.

CAT: BRP-01815

MF: C33H32N5O6

MF: 595.65

Purity: ≥98% by HPLC

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InChIKey: BBHYMFPOKIVUSI-YUGARCTCSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(trityloxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C33H33N5O6/c1-20(2)29(41)36-32-35-28-25(30(42)37-32)34-19-38(28)31-27(40)26(39)24(44-31)18-43-33(21-12-6-3-7-13-21,22-14-8-4-9-15-22)23-16-10-5-11-17-23/h3-17,19-20,24,26-27,31,39-40H,18H2,1-2H3,(H2,35,36,37,41,42)/t24-,26-,27-,31-/m1/s1

Synonyms: 5'-O-Trt-N2-ibu-rG; N-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

5'-O-Tritylinosine

Description: KIN59 is a purine riboside derivative that suppresses thymidine phosphorylase (TPase). TPase is an enzyme catalyzing the reversible phosphorolysis of pyrimidine deoxynucleosides to 2-deoxy-d-ribose-1-phosphate and their respective pyrimidine bases. KIN59 noncompetitively inhibits TPase-induced angiogenesis in the chorioallantoic membrane assay.

CAT: BRP-01816

CAS: 4152-77-6

MF: C29H26N4O5

MF: 510.55

Purity: ≥98% by HPLC

Appearance: Crystalline Solid

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Storage: Store at -20°C

Density: 1.40±0.1 g/cm3

Melting Point: 207-210 °C

Boiling Point: 813.6±65.0 °C at 760 mmHg

InChIKey: YEPZMZDCXFRHCL-ZYWWQZICSA-N

Solubility: Soluble in DMF, DMSO, Ethanol

CanonicalSMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCC4C(C(C(O4)N5C=NC6=C5N=CNC6=O)O)O

IUPAC Name: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(trityloxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C29H26N4O5/c34-24-22(38-28(25(24)35)33-18-32-23-26(33)30-17-31-27(23)36)16-37-29(19-10-4-1-5-11-19,20-12-6-2-7-13-20)21-14-8-3-9-15-21/h1-15,17-18,22,24-25,28,34-35H,16H2,(H,30,31,36)/t22-,24-,25-,28-/m1/s1

Synonyms: 5'-Trt-rI; (2R,3R,4S,5R)-9-(3,4-Dihydroxy-5-trityloxymethyl-tetrahydrofuran-2-yl)-1,9-dihydropurin-6-one; KIN-59; Inosine, 5'-O-(triphenylmethyl)-; 5'-O-(triphenylmethyl)-inosine; 5'-O-(Triphenylmethyl)inosine; Inosine, 5'-O-trityl-; KIN59; KIN 59

2'-O-Methyl-5'-O-DMTr-5-iodouridine

Description: 5'-O-(Dimethoxytrityl)-5-iodo-2'-O-methyluridine is a reagent used in the synthesis of oligonucleotides (ODNs) containing 5-(N-aminohexyl)carbamoyl-2'-O-methyluridine which is resistant to nucleolytic hydrolysis.

CAT: BRP-01817

CAS: 588691-24-1

MF: C31H31IN2O8

MF: 686.49

Purity: ≥95%

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Density: 1.58±0.1 g/cm3

InChIKey: VYNNFLLSYDWMCJ-LTGLEFCMSA-N

CanonicalSMILES: COC1C(C(OC1N2C=C(C(=O)NC2=O)I)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O

IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-5-iodopyrimidine-2,4-dione

InChI: InChI=1S/C31H31IN2O8/c1-38-22-13-9-20(10-14-22)31(19-7-5-4-6-8-19,21-11-15-23(39-2)16-12-21)41-18-25-26(35)27(40-3)29(42-25)34-17-24(32)28(36)33-30(34)37/h4-17,25-27,29,35H,18H2,1-3H3,(H,33,36,37)/t25-,26-,27-,29-/m1/s1

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-5-Iodo-2'-O-Methyluridine; 5'-O-(Dimethoxytrityl)-5-iodo-2'-O-methyluridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-iodo-2'-O-methyl-uridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 5-Iodo-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-Uridine

5'-O-(4,4'-Dimethoxytrityl)-N4-Acetyl-5-Iodo-Cytidine

Description: 5'-O-(4,4'-Dimethoxytrityl)-N4-Acetyl-5-Iodo-Cytidine, a nucleoside analog utilized in the management of neoplastic diseases, has demonstrated its efficacy by obstructing DNA synthesis, thereby hindering tumor cell progression. With well-established usage in biomedical studies, this product is a valuable resource for comprehending DNA replication as well as repair mechanisms and developing innovative anticancer therapeutics.

CAT: BRP-01818

MF: C32H32IN3O8

MF: 713.52

Purity: ≥98% by HPLC

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InChIKey: WQTCLOQRQHSBBY-NODMTMHWSA-N

IUPAC Name: N-(1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-5-iodo-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

InChI: InChI=1S/C32H32IN3O8/c1-19(37)34-29-25(33)17-36(31(40)35-29)30-28(39)27(38)26(44-30)18-43-32(20-7-5-4-6-8-20,21-9-13-23(41-2)14-10-21)22-11-15-24(42-3)16-12-22/h4-17,26-28,30,38-39H,18H2,1-3H3,(H,34,35,37,40)/t26-,27-,28-,30-/m1/s1

Synonyms: 5'-DMT-Ac-5-I-rC; 5'-O-DMT-5-I-rC(Ac); N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-iodocytidine

5'-O-DMT-5-iodouridine

Description: 5'-O-DMT-5-iodouridine, an extraordinary compound thriving in the biomedical realm, plays a pivotal role within the pharmaceutical sphere. Facilitating the evolution of nucleoside-based medicinal concoctions, this remarkable product revolutionizes the therapeutic landscape, championing the battle against afflictions such as viral infections and particular variants of malignancy. Its inherent molecular idiosyncrasies position it as an invaluable asset, empowering the arsenal of biomedicine by propelling precision healthcare and enabling targeted remedial interventions.

CAT: BRP-01819

CAS: 158728-68-8

MF: C30H29IN2O8

MF: 672.46

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

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Storage: Store at 2-8°C

Density: 1.64±0.1 g/cm3

InChIKey: GOLQPGCNIAQGQO-IYUNARRTSA-N

CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=C(C(=O)NC5=O)I)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-5-iodopyrimidine-2,4-dione

InChI: InChI=1S/C30H29IN2O8/c1-38-21-12-8-19(9-13-21)30(18-6-4-3-5-7-18,20-10-14-22(39-2)15-11-20)40-17-24-25(34)26(35)28(41-24)33-16-23(31)27(36)32-29(33)37/h3-16,24-26,28,34-35H,17H2,1-2H3,(H,32,36,37)/t24-,25-,26-,28-/m1/s1

Synonyms: 5'-O-(4,4'-Dimethyltrityl)-5-iodouridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-iodouridine; 1-{(2R,3R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3,4-dihydroxy-tetrahydro-furan-2-yl}-5-iodo-1H-pyrimidine-2,4-dione; 5'-O-DMT-5-I-rU

5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine

Description: 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is an immensely powerful biomedical compound, used in the research of inflammatory disorders and autoimmune diseases. This exquisite molecule, through its adept nature, selectively engages receptors and signaling pathways, exuding anti-inflammatory prowess.

CAT: BRP-01820

CAS: 128219-81-8

MF: C40H39N5O8

MF: 717.77

Purity: ≥98% by HPLC

Appearance: White to pale yellow powder

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Storage: Store at 2-8°C

Density: 1.32±0.1 g/cm3

InChIKey: WXVUPMVJIZZBQJ-FCOKYAGUSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)COC4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]purin-6-yl]-2-phenoxyacetamide

InChI: InChI=1S/C40H39N5O8/c1-48-29-18-14-27(15-19-29)40(26-10-6-4-7-11-26,28-16-20-30(49-2)21-17-28)52-22-32-35(47)36(50-3)39(53-32)45-25-43-34-37(41-24-42-38(34)45)44-33(46)23-51-31-12-8-5-9-13-31/h4-21,24-25,32,35-36,39,47H,22-23H2,1-3H3,(H,41,42,44,46)/t32-,35-,36-,39-/m1/s1

Synonyms: 5'-DMT-2'-(O-Methyl) Adenosine (n-PAC); 5'-O-(4,4'-Dimethoxytrityl)-N6-Phenoxyacetyl-2'-O-methyl-Adenosine; 5'-O-DMT-N6-PAc-2'-OMe-rA; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-phenoxyacetyl)adenosine; 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine; 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyl-D-adenosine; 5'-O-DMT-2'-OMe-N6-Pac-rA

5'-O-DMT-3'-O-TBDMS-2'-O-methyl-Uridine

Description: 5'-O-DMT-3'-O-TBDMS-2'-O-methyl-Uridine is a pivotal compound in nucleotide biosynthesis, deemed indispensable in the production of oligonucleotides used for gene expression research and DNA sequencing. Its comprehensive applicability also extends to the creation of antivirals that combat diseases, encompassing cancer and hepatitis C, and thus, embodies an essential tool in the arsenal of medicinal chemists.

CAT: BRP-01821

CAS: 171268-85-2

MF: C37H46N2O8Si

MF: 674.87

Purity: ≥98% by HPLC

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Density: 1.21±0.1 g/cm3

InChIKey: ZWQRHEIYDFEUMS-DWNQJFHRSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1OC)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C37H46N2O8Si/c1-36(2,3)48(7,8)47-32-30(46-34(33(32)44-6)39-23-22-31(40)38-35(39)41)24-45-37(25-12-10-9-11-13-25,26-14-18-28(42-4)19-15-26)27-16-20-29(43-5)21-17-27/h9-23,30,32-34H,24H2,1-8H3,(H,38,40,41)/t30-,32-,33-,34-/m1/s1

Synonyms: 5'-O-DMT-3'-O-TBDMS-2'-OMe-U; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyl-

5'-O-DMT-2'-O-Propylphthalimido-5-Methy-Uridine

Description: 5'-O-DMT-2'-O-Propylphthalimido-5-Methy-Uridine is a highly specialized synthetic nucleoside compound that has garnered significant attention in the scientific community due to its antiviral activity against HIV-1 and HSV-2. Its unique chemical structure allows for targeted treatment of viral infections, making it an incredibly valuable tool in the ongoing fight against these debilitating diseases. Additionally, recent studies have shown promising results in its potential use as a therapy for leukemia, highlighting its versatility as a research tool. Researchers in the field of virology and oncology alike continue to explore the multifaceted potential of 5'-O-DMT-2'-O-Propylphthalimido-5-Methy-Uridine, making it a pivotal molecule in the world of medical research.

CAT: BRP-01822

MF: C42H41N3O10

MF: 747.80

Purity: ≥98% by HPLC

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Density: 1.3±0.1 g/cm3

Boiling Point: 892.5±75.0°C at 760 mmHg

InChIKey: CJZDRODFMDMJFQ-NFCWHMTKSA-N

CanonicalSMILES: Cc1cn(c(=O)nc1O)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(c3ccccc3)(c4ccc(cc4)OC)c5ccc(cc5)OC)O)OCCCN6C(=O)c7ccccc7C6=O

IUPAC Name: 2-(3-(((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)oxy)propyl)isoindoline-1,3-dione

InChI: InChI=1S/C42H41N3O10/c1-26-24-45(41(50)43-37(26)47)40-36(53-23-9-22-44-38(48)32-12-7-8-13-33(32)39(44)49)35(46)34(55-40)25-54-42(27-10-5-4-6-11-27,28-14-18-30(51-2)19-15-28)29-16-20-31(52-3)21-17-29/h4-8,10-21,24,34-36,40,46H,9,22-23,25H2,1-3H3,(H,43,47,50)/t34-,35-,36-,40-/m1/s1

Synonyms: 5'-O-DMT-2'-O-Propylphthalimido-5-Me-U; 1-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-O-[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propyl]-β-D-ribofuranosyl}-4-hydroxy-5-methyl-2(1H)-pyrimidinone; 2(1H)-Pyrimidinone, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]-β-D-ribofuranosyl]-4-hydroxy-5-methyl-

5'-O-DMT-3'-O-Propargyl-Uridine

Description: 5'-O-DMT-3'-O-Propargyl-Uridine, a modified nucleoside with vast employment in the realm of biomedicine, is a potential therapeutic medium for tackling a range of disorders inclusive of cancer and viral infections. Used as either a research implement to study DNA and RNA, or a therapeutic agent, this product's noteworthy characteristics, and consequential therapeutic advantages, characterize it as an indispensable component in biomedicine.

CAT: BRP-01823

CAS: 171486-58-1

MF: C33H32N2O8

MF: 584.63

Purity: ≥97% by HPLC

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Density: 1.35±0.1 g/cm3 (Predicted)

InChIKey: LNXJXLICXRQADN-PMFUCWTESA-N

CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)O)OCC#C

IUPAC Name: 1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-hydroxy-4-prop-2-ynoxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C33H32N2O8/c1-4-20-41-30-27(43-31(29(30)37)35-19-18-28(36)34-32(35)38)21-42-33(22-8-6-5-7-9-22,23-10-14-25(39-2)15-11-23)24-12-16-26(40-3)17-13-24/h1,5-19,27,29-31,37H,20-21H2,2-3H3,(H,34,36,38)/t27-,29-,30-,31-/m1/s1

Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-2-propyn-1-yl-; 5-O-(4,4'-dimethoxytrityl)-1-deoxy-3-O-prop-2-ynyl-1-uracil-1-yl-beta-D-ribo-pentofuranose; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-O-2-propyn-1-yluridine; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-2-propynyl-; 5'-O-(Dimethoxytrityl)-3'-O-propargyluridine; 1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-hydroxy-4-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

5'-O-DMT-2'-O-TBDMS-L-Uridine

Description: 5'-O-DMT-2'-O-TBDMS-L-Uridine is a vital compound in compound used for the development of neucleosides, specifically for the research of viral infections and cancers. It is a versatile building block utilized in the development of anti-viral and anti-cancer drugs due to its ability to alter gene expression and inhibit viral replication.

CAT: BRP-01824

CAS: 144385-61-5

MF: C36H44N2O8Si

MF: 660.84

Purity: ≥97% by HPLC

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Density: 1.24±0.1 g/cm3

InChIKey: KVHQIELPHWJPSY-BBXFGWPUSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O

IUPAC Name: 1-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C36H44N2O8Si/c1-35(2,3)47(6,7)46-32-31(40)29(45-33(32)38-22-21-30(39)37-34(38)41)23-44-36(24-11-9-8-10-12-24,25-13-17-27(42-4)18-14-25)26-15-19-28(43-5)20-16-26/h8-22,29,31-33,40H,23H2,1-7H3,(H,37,39,41)/t29-,31-,32-,33-/m0/s1

Synonyms: 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione; 5-O-(4,4'-dimethoxytrityl)-2-O-(tert-butyl-dimethyl-silyl)-1-deoxy-1-uracil-1-yl-beta-L-ribo-pentofuranose; 5'-O-DMT-2'-O-TBDMS-L-rU

5'-O-DMT-2'-O-(tertbutyldimethylsilyl)-N6-Benzoyl-L-Adenosine

Description: 5'-O-DMT-2'-O-(tertbutyldimethylsilyl)-N6-Benzoyl-L-Adenosine is a potent adenosine analog commonly used in biomedical research. It acting as a versatile chemical tool for studying adenosine receptors and their signaling pathways. Additionally, it finding applications in the development of new drugs targeting adenosine-related diseases, such as inflammation is asthma, cardiovascular disorders is and cancer.

CAT: BRP-01825

MF: C44H49N5O7Si

MF: 787.99

Purity: ≥97% by HPLC

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Density: 1.2±0.1 g/cm3

InChIKey: DAZIGOPASNJPCJ-FQBWDSEVSA-N

CanonicalSMILES: O=C(NC1=NC=NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(O)C3O[Si](C)(C)C(C)(C)C)C=7C=CC=CC7

IUPAC Name: N-(9-((2S,3S,4S,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

InChI: InChI=1S/C44H49N5O7Si/c1-43(2,3)57(6,7)56-38-37(50)35(55-42(38)49-28-47-36-39(45-27-46-40(36)49)48-41(51)29-14-10-8-11-15-29)26-54-44(30-16-12-9-13-17-30,31-18-22-33(52-4)23-19-31)32-20-24-34(53-5)25-21-32/h8-25,27-28,35,37-38,42,50H,26H2,1-7H3,(H,45,46,48,51)/t35-,37-,38-,42-/m0/s1

Synonyms: 5'-O-DMT-2'-O-TBDMS-N6-Bz-L-rA; 5'-O-DMT-2'-O-TBDMS-L-rA(Bz); N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-L-adenosine; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-L-adenosine

N2-Phenylacetylguanosine

Description: N2-Phenylacetylguanosine is a modified form of guanosine, a nucleoside composed of guanine linked to a ribose sugar. In this modified form, a phenylacetyl group is attached to the nitrogen atom (N2) of the guanine base. This modification can alter the properties of guanosine, potentially affecting its interactions with other molecules, such as proteins or nucleic acids. N2-Phenylacetylguanosine may be used in various biochemical and biomedical studies, including research on RNA modification, nucleic acid chemistry, and drug development targeting guanosine metabolism or signaling pathways.

CAT: BRP-01826

CAS: 132628-16-1

MF: C18H19N5O6

MF: 401.37

Purity: ≥95% by HPLC

Appearance: White to Off-white Powder

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Storage: Store at 2-8°C

Density: 1.73±0.1 g/cm3

Melting Point: 189 °C

InChIKey: IRSCBAKCFOLZNC-IWCJZZDYSA-N

CanonicalSMILES: C1=CC=C(C=C1)CC(=O)NC2=NC3=C(C(=O)N2)N=CN3C4C(C(C(O4)CO)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-phenylacetamide

InChI: InChI=1S/C18H19N5O6/c24-7-10-13(26)14(27)17(29-10)23-8-19-12-15(23)21-18(22-16(12)28)20-11(25)6-9-4-2-1-3-5-9/h1-5,8,10,13-14,17,24,26-27H,6-7H2,(H2,20,21,22,25,28)/t10-,13-,14-,17-/m1/s1

Synonyms: N2-Phenylacetyl guanosine; N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-phenylacetamide; N-(Phenylacetyl)guanosine; 2-N-(phenylacetyl)guanosine; ribo Guanosine (n-Phenyl acetyl); N2-Phenylacetyl-Guanosine; N-(2-Phenylacetyl)guanosine

N6-Methyladenosine

Description: N6-Methyladenosine is an abundant modification in mRNA and is found within some viruses, and most eukaryotes including mammals, insects, plants and yeast.

CAT: BRP-01827

CAS: 1867-73-8

MF: C11H15N5O4

MF: 281.27

Purity: >98%

Appearance: White Solid

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Storage: Store at 2-8°C

Density: 1.85±0.1 g/cm3 (Predicted)

Melting Point: 172°C

Boiling Point: 649.1±65.0°C (Predicted)

Flash Point: 346.3°C

Symbol: m⁶A

InChIKey: VQAYFKKCNSOZKM-IOSLPCCCSA-N

Solubility: Soluble in DMSO (10 mM)

CanonicalSMILES: CNC1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methylamino)purin-9-yl]oxolane-3,4-diol

InChI: InChI=1S/C11H15N5O4/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11,17-19H,2H2,1H3,(H,12,13,14)/t5-,7-,8-,11-/m1/s1

Synonyms: 6-Methyladenosine; N(6)-Methyladenosine; N-Methyladenosine; 6-Methylaminopurinosine; 6-Methylaminopurine D-riboside; 6-Methylaminopurine ribonucleoside; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol; NSC 29409; 6-Methylamino-9-β-D-ribofuranosylpurine; 6-Methylaminopurine riboside; 9-β-D-Ribofuranosyl-N6-methylaminopurine; N6-methyladenosine (m6A)