Nucleosides - RNA / BOC Sciences

3-Deazaadenosine hydrochloride

Description: It is an S-adenosine homocysteine hydrolase inhibitor. It has anti-inflammatory effects, inhibiting leukocyte adhesion and chemotaxis, lymphocyt-mediated cytolysis, phagocytosis, degranulation and NF-κB signal transduction.

CAT: BRP-01845

CAS: 86583-19-9

MF: C11H15ClN4O4

MF: 302.71

Purity: ≥97% by HPLC

Appearance: Crystalline solid

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Storage: Store at 2-8°C

Shelf Life: >3 years if stored properly

InChIKey: WQRKYGAAEYXMKZ-RPWKAPHTSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: C1=CN=C(C2=C1N(C=N2)C3C(C(C(O3)CO)O)O)N.Cl

IUPAC Name: (2R,3R,4S,5R)-2-(4-aminoimidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol;hydrochloride

InChI: InChI=1S/C11H14N4O4.ClH/c12-10-7-5(1-2-13-10)15(4-14-7)11-9(18)8(17)6(3-16)19-11;/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13);1H/t6-,8-,9-,11-;/m1./s1

Synonyms: 3-Deaza-Adenosine hydrochloride; 3-Deaza-rA Hcl; 1-(β-D-Ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine hydrochloride (1:1); 1H-Imidazo[4,5-c]pyridin-4-amine, 1-β-D-ribofuranosyl-, hydrochloride (1:1)

Related CAS: 6736-58-9 (free base)

5-[3-(Trifluoroacetamido)-1-(E)-propenyl]uridine

Description: 5-[3-(Trifluoroacetamido)-1-(E)-propenyl]uridine is used in the biomedical industry for its potential role in studying viral diseases. It may have antiviral properties due to the presence of uridine derivatives and the trifluoroacetamido group.

CAT: BRP-01846

CAS: 869222-68-4

MF: C14H16F3N3O7

MF: 395.29

Purity: ≥98% by HPLC

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Storage: Store at 2-8°C

Density: 1.682±0.06 g/cm3 (Predicted)

InChIKey: DMXZSDJKAIYXMV-TVIFIVJDSA-N

CanonicalSMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)C=CCNC(=O)C(F)(F)F

IUPAC Name: N-[(E)-3-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enyl]-2,2,2-trifluoroacetamide

InChI: InChI=1S/C14H16F3N3O7/c15-14(16,17)12(25)18-3-1-2-6-4-20(13(26)19-10(6)24)11-9(23)8(22)7(5-21)27-11/h1-2,4,7-9,11,21-23H,3,5H2,(H,18,25)(H,19,24,26)/b2-1+/t7-,8-,9-,11-/m1/s1

Synonyms: N-((E)-3-(1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)allyl)-2,2,2-trifluoroacetamide; 5-TFA-aa-uridine; 5-TFA-aa-U; (E)-5-[3-(Trifluoroacetamido)-1-propenyl]uridine; 5-{(1E)-3-[(Trifluoroacetyl)amino]-1-propen-1-yl}uridine; Uridine, 5-[(1E)-3-[(trifluoroacetyl)amino]-1-propenyl]-

8-Bromoguanosine

Description: 8-Bromo-guanosine, an extensively studied chemical entity, manifests remarkable potency in the realm of biomedicine owing to its ability to obstruct viral RNA synthesis.

CAT: BRP-01847

CAS: 4016-63-1

MF: C10H12BrN5O5

MF: 362.14

Purity: ≥98% by HPLC

Appearance: White Crystalline Powder

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Storage: Store at -20°C

Density: 2.62±0.1 g/cm3

Melting Point: >180 °C (dec.)

Boiling Point: 774.0±70.0 °C at 760 mmHg

InChIKey: ASUCSHXLTWZYBA-UMMCILCDSA-N

Solubility: Soluble in DMSO, Methanol (Sparingly), Hot Water

CanonicalSMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2Br)O)O)O

IUPAC Name: 2-amino-8-bromo-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H12BrN5O5/c11-9-13-3-6(14-10(12)15-7(3)20)16(9)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H3,12,14,15,20)/t2-,4-,5-,8-/m1/s1

Synonyms: 8-Bromo-guanosine; 8-Bromo-ribo Guanosine; 2-Amino-8-bromo-6-hydroxypurine Riboside; NSC 174257; NSC 79211; 2-amino-8-bromo-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 8-Bromo-D-guanosine; 8-Bromo-9-β-D-ribofuranosylguanine

8-Iodoadenosine

Description: 8-Iodoadenosine, a biomedical product, has emerged as a pivotal intervention for diverse ailments and medical circumstances. This compound exhibits exceptional prospects in oncological investigations, particularly pertaining to the innovation of avant-garde anticancer modalities. Profoundly impeding cellular mechanisms, it manifests as a strong suppressor of cancerous cell propagation whilst concurrently instigating apoptosis.

CAT: BRP-01849

CAS: 31281-88-6

MF: C10H12IN5O4

MF: 393.14

Purity: 97%

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Storage: Store at 2-8°C (under dark)

Density: 2.69±0.1 g/cm3(Predicted)

Boiling Point: 730.4±70.0 °C(Predicted)

InChIKey: CYOIMLAHGVOKIG-UUOKFMHZSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C(=N2)I)C3C(C(C(O3)CO)O)O)N

IUPAC Name: (2R,3R,4S,5R)-2-(6-amino-8-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H12IN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)/t3-,5-,6-,9-/m1/s1

Synonyms: 8-Indoo adenosine; 8-I-rA; 8-I-Adenosine; (2R,3R,4S,5R)-2-(6-Amino-8-iodo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Adenosine, 8-iodo-

5-Fluoro Uridine

Description: 5-Fluoro uridine is a fluorinated analog of uridine, which is a nucleoside that forms part of RNA. 5-Fluoro uridine is a valuable compound in both research and clinical settings due to its ability to disrupt RNA function and inhibit cancer cell growth. Its fluorinated structure makes it a potent analog of uridine with significant biological activity.

CAT: BRP-01850

CAS: 316-46-1

MF: C9H11FN2O6

MF: 262.19

Purity: 97%

Appearance: White Powder

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Storage: Store at 2-8°C

Density: 1.77±0.1 g/cm3 (Predicted)

Melting Point: 151-152°C

InChIKey: FHIDNBAQOFJWCA-UAKXSSHOSA-N

Solubility: Soluble in Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)F

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione

InChI: InChI=1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1

Synonyms: 5-Fur; Uridine, 5-fluoro-; Fluorouridine; 5-fluoro-1-(beta-d-ribofuranosyl)uracil; FUrd; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-fluoro-D-uridine; 1-beta-D-Arabinofuranosyl-5-fluoro-(1H,3H)-pyrimidine-2,4-dione; 5-FUrd; NSC 146604; NSC 519273; 5-Fluorouridine

8-Bromoadenosine

Description: 8-Bromoadenosine is an adenosine binding inhibitor. 8-Bromoadenosine is a modified nucleoside with a bromine atom at the 8-position of the adenine base. It is used in biochemical research to study nucleic acid structure and function, and to investigate interactions between nucleic acids and proteins.

CAT: BRP-01851

CAS: 2946-39-6

MF: C10H12BrN5O4

MF: 346.14

Purity: ≥97% by HPLC

Appearance: Off-white to pale beige solid

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Storage: Store at 2-8 °C

Density: 2.45±0.1 g/cm³

Melting Point: >183 °C (dec.)

Boiling Point: 717.7±70.0 °C at 760 mmHg

InChIKey: VJUPMOPLUQHMLE-UUOKFMHZSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Sonicated)

CanonicalSMILES: C1=NC2=C(C(=N1)N)N=C(N2C3C(C(C(O3)CO)O)O)Br

IUPAC Name: (2R,3R,4S,5R)-2-(6-amino-8-bromopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H12BrN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)/t3-,5-,6-,9-/m1/s1

Synonyms: 8-Bromo-ribo Adenosine; 6-Amino-8-bromopurine Riboside; NSC 79213; 8-Bromo Adenosine; (2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Bromoadenosine; 8-Bromo-adenosine; 8-Bromoadenine-9-β-D-ribofuranoside

2-Cl-Ino

Description: 2-Cl-Ino is the potential metabolite of 2-chloro adenosine with a hypotensive effect. It is often uesd as a starting structure for nucleosides and nucleotides modification.

CAT: BRP-01852

CAS: 13276-43-2

MF: C10H11ClN4O6

MF: 302.67

Purity: ≥98% by HPLC

Appearance: White to Beige Solid

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Storage: Store at -20°C under inert atmosphere

Density: 2.19±0.1 g/cm3

Melting Point: >140°C (dec.)

Boiling Point: 636.6±65.0°C at 760 mmHg

InChIKey: NDSPCQCIHGSYAS-UUOKFMHZSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Sonicated)

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(NC2=O)Cl

IUPAC Name: 2-chloro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H11ClN4O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H,13,14,19)/t3-,5-,6-,9-/m1/s1

Synonyms: 2-Chloroinosine; (2R,3R,4S,5R)-2-(2-Chloro-6-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2-Chloro-D-inosine; 2-Chloro-9-b-D-ribofuranosyl-6H-purin-6-one

5-Bromo-uridine (5-BrU)

Description: 5-Bromo-uridine (5-BrU) is a vital tool used in biomedicine for cellular and molecular research. Primarily, it is employed in studying RNA synthesis and exploring cellular processes like transcription and translation. With its ability to substitute uridine in RNA synthesis, 5-BrU aids in investigating RNA-related diseases and developing potential therapeutic interventions.

CAT: BRP-01853

CAS: 957-75-5

MF: C9H11BrN2O6

MF: 323.10

Purity: ≥98% by HPLC

Appearance: White Crystalline Powder

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Storage: Store at -20°C

Density: 2.043 g/cm3

Melting Point: >130°C (dec.)

Application: Anti-Infective Agents

InChIKey: AGFIRQJZCNVMCW-UAKXSSHOSA-N

Solubility: Soluble in Water (Sonicated)

CanonicalSMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)Br

IUPAC Name: 5-bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H11BrN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1

Synonyms: 5-Bromouridine; (-)-5-Bromouridine; NSC 38296; 1-beta-Ribofuranosyl-5-bromo-uracil; 5-Bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5-bromo-1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione; 5-Bromo Uridine

2'-O-Methyl-5-iodouridine

Description: 5-Iodo-2'-O-methyluridine is a nucleoside analog (NSA) which acts as a chemotherapeutic agent for the induction of neuronal differentiation.

CAT: BRP-01854

CAS: 34218-84-3

MF: C10H13IN2O6

MF: 384.12

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at RT

Density: 2.04±0.1 g/cm3 (Predicted)

InChIKey: PLVDDNNLEWFJNQ-JXOAFFINSA-N

CanonicalSMILES: COC1C(C(OC1N2C=C(C(=O)NC2=O)I)CO)O

IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-5-iodopyrimidine-2,4-dione

InChI: InChI=1S/C10H13IN2O6/c1-18-7-6(15)5(3-14)19-9(7)13-2-4(11)8(16)12-10(13)17/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6-,7-,9-/m1/s1

Synonyms: 2'-(O-Methyl)-5-Iodo Uridine; 5-Iodo-2'-O-methyluridine; 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 5-Iodo-2'-OMe-2'-dU; 2'-OMe-5-I-U; 2'-OMe-5-I-Uridine

N-Cyclopentyl-2'-C-methyl-adenosine

Description: N-Cyclopentyl-2'-C-methyl-adenosine (CPMA) is a highly efficacious and specifically targeted agonist of adenosine A2A receptors, used for studying diverse pathological conditions including Parkinson's disease, cancer and inflammation.

CAT: BRP-01856

CAS: 205171-06-8

MF: C16H23N5O4

MF: 349.39

Purity: ≥97% by HPLC

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Storage: Store at 2-8°C

Density: 1.67±0.1 g/cm3

Boiling Point: 657.1±65.0°C at 760 mmHg

InChIKey: BVOLJUDYJILMMW-QTDMDRALSA-N

CanonicalSMILES: CC1(C(C(OC1N2C=NC3=C2N=CN=C3NC4CCCC4)CO)O)O

IUPAC Name: (2R,3R,4R,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)-3-methyloxolane-3,4-diol

InChI: InChI=1S/C16H23N5O4/c1-16(24)12(23)10(6-22)25-15(16)21-8-19-11-13(17-7-18-14(11)21)20-9-4-2-3-5-9/h7-10,12,15,22-24H,2-6H2,1H3,(H,17,18,20)/t10-,12-,15-,16-/m1/s1

Synonyms: (2R,3R,4R,5R)-2-(6-(Cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol; Adenosine, N-cyclopentyl-2'-C-methyl-; N-Cyclopentyl-2'-methyladenosine; 9-(2'-C-methyl-beta-D-ribofuranosyl)-6-(cyclopentylamino)purine; N6-Cyclopentyl-2'-C-methyl-adenosine; Adenosine, N-cyclopentyl-2'-C-methyl-; N-Cyclopentyl-2'-C-methyladenosine

N4-Methylcytidine

Description: N4-Methylcytidine is a paramount biochemical compound, owing to its prospective involvement in studying neoplastic and virulent maladies. Derived from cytidine, N4-Methylcytidine showcases auspicious anti-oncogenic and antiviral traits.

CAT: BRP-01857

CAS: 10578-79-7

MF: C10H15N3O5

MF: 257.24

Purity: ≥95%

Appearance: Off-white to Beige Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.69±0.1 g/cm3 (Predicted)

Melting Point: 202-203 °C

Boiling Point: 504.2±60.0 °C at 760 mmHg

Symbol: m⁵C

InChIKey: LZCNWAXLJWBRJE-ZOQUXTDFSA-N

Solubility: Soluble in Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: CNC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(methylamino)pyrimidin-2-one

InChI: InChI=1S/C10H15N3O5/c1-11-6-2-3-13(10(17)12-6)9-8(16)7(15)5(4-14)18-9/h2-3,5,7-9,14-16H,4H2,1H3,(H,11,12,17)/t5-,7-,8-,9-/m1/s1

Synonyms: N-Methylcytidine; N-4-Methylcytidine; NSC 518744; 1-((2R,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-4-(methylamino)pyrimidin-2(1H)-one; 4-Methylcytidine

8-(Benzyloxy)guanosine

Description: 8-(Benzyloxy)guanosine is a vital bioactive compound exhibiting potential in studying various diseases, such as cancer. With its inhibition abilities, it targets specific cellular pathways.

CAT: BRP-01858

CAS: 3868-36-8

MF: C17H19N5O6

MF: 389.36

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20°C

Density: 1.8±0.1 g/cm3

Melting Point: >190°C (dec.)

Boiling Point: 772°C at 760 mmHg

InChIKey: RNSGUQLXDMZREX-SDBHATRESA-N

Solubility: Soluble in DMSO (Slightly)

CanonicalSMILES: C1=CC=C(C=C1)COC2=NC3=C(N2C4C(C(C(O4)CO)O)O)N=C(NC3=O)N

IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-1H-purin-6-one

InChI: InChI=1S/C17H19N5O6/c18-16-20-13-10(14(26)21-16)19-17(27-7-8-4-2-1-3-5-8)22(13)15-12(25)11(24)9(6-23)28-15/h1-5,9,11-12,15,23-25H,6-7H2,(H3,18,20,21,26)/t9-,11-,12-,15-/m1/s1

Synonyms: 8-Benzyloxy-Guanosine; 8-(Phenylmethoxy)guanosine; NSC 90391; 8-Benzyloxyguanosine; 2-Amino-8-(benzyloxy)-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; Guanosine, 8-(phenylmethoxy)-; Guanosine, 8-(benzyloxy)-

7,8-Dihydro-8-thioxo-adenosine

Description: 7,8-Dihydro-8-thioxo-adenosine is a potent synthetic compound exhibiting antiviral properties against certain RNA viruses by inhibiting viral replication. Additionally, it has shown potential in studying chronic lymphocytic leukemia.

CAT: BRP-01859

CAS: 3001-45-4

MF: C10H13SN5O4

MF: 299.31

Purity: 95%

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Storage: Store at 2-8 °C, protect from light

Density: 1.86±0.1 g/cm3

Melting Point: 175 °C (dec.)

Boiling Point: 640.3±65.0 °C at 760 mmHg

InChIKey: QILZVYQRHGBEAR-UUOKFMHZSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C(=S)N2)C3C(C(C(O3)CO)O)O)N

IUPAC Name: 6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7H-purine-8-thione

InChI: InChI=1S/C10H13N5O4S/c11-7-4-8(13-2-12-7)15(10(20)14-4)9-6(18)5(17)3(1-16)19-9/h2-3,5-6,9,16-18H,1H2,(H,14,20)(H2,11,12,13)/t3-,5-,6-,9-/m1/s1

Synonyms: 8-Mercaptoadenosine; 6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-purine-8(9H)-thione; 8-Thioadenosine; 7,8-Dihydro-8-thioxoadenosine; 9H-Purine-8-thiol, 6-amino-9-β-D-ribofuranosyl-; 8-Thioxoadenosine; 8H-Purine-8-thione, 6-amino-7,9-dihydro-9-β-D-ribofuranosyl-; Chembridge 5790637; NSC 90395

CF-102

Description: CF-102 is an orally bioavailable, synthetic, highly selective adenosine A3 receptor (A3AR) agonist with potential antineoplastic activity. Adenosine A3 receptor agonist CF102 selectively binds to and activates the cell surface-expressed A3AR, deregulating Wnt and NF-kB signal transduction pathways downstream, which may result in apoptosis of A3AR-expressing tumor cells. A3AR, a G protein-coupled receptor, is highly expressed on the cell surfaces of various solid tumor cell types, including hepatocellular carcinoma (HCC) cells, and plays an important role in cellular proliferation.

CAT: BRP-01860

CAS: 163042-96-4

MF: C18H18ClIN6O4

MF: 544.73

Purity: ≥98% by HPLC

Appearance: White to Off-white Solid

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Storage: Store at -20°C

Density: 2.04±0.1 g/cm3 at 20°C, 760 Torr

Melting Point: 205-209°C

Application: Purinergic P1 Receptor Agonists

InChIKey: IPSYPUKKXMNCNQ-PFHKOEEOSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)

CanonicalSMILES: CNC(=O)C1C(C(C(O1)N2C=NC3=C2N=C(N=C3NCC4=CC(=CC=C4)I)Cl)O)O

IUPAC Name: (2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide

InChI: InChI=1S/C18H18ClIN6O4/c1-21-16(29)13-11(27)12(28)17(30-13)26-7-23-10-14(24-18(19)25-15(10)26)22-6-8-3-2-4-9(20)5-8/h2-5,7,11-13,17,27-28H,6H2,1H3,(H,21,29)(H,22,24,25)/t11-,12+,13-,17+/m0/s1

Synonyms: Chloro-IB-MECA; 2-Chloro-N6-(3-iodobenzyl)-adenosine-5'-N-methyluronamide; 2-Cl-IB-MECA; 1-[2-Chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide; Namodenoson; (2S,3S,4R,5R)-5-(2-Chloro-6-((3-iodobenzyl)amino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide; Cl-IB-MECA; CF102; CF 102

8-Thioguanosine

Description: 8-Thioguanosine is a significant compound exhibiting remarkable capabilities in studying viral infections and cancer. By proficiently curtailing viral RNA and DNA replication, it effectively subdues the menace of virulence, while concurrently impeding the enhancement of nucleic acids within cancerous cells.

CAT: BRP-01861

CAS: 26001-38-7

MF: C10H13N5O5S

MF: 315.31

Purity: ≥97% by HPLC

Appearance: Off-white to Grey Solid

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Storage: Store at 2-8°C under inert atmosphere

Density: 2.35±0.1 g/cm3 (Predicted)

Melting Point: >216°C (dec.)

Boiling Point: 595.1±60.0°C at 760 mmHg

Application: Adjuvants, Immunologic

InChIKey: KZELNMSPWPFAEB-UMMCILCDSA-N

Solubility: Soluble in DMSO (Slightly)

CanonicalSMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)NC2=S)O)O)O

IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-sulfanylidene-1,7-dihydropurin-6-one

InChI: InChI=1S/C10H13N5O5S/c11-9-13-6-3(7(19)14-9)12-10(21)15(6)8-5(18)4(17)2(1-16)20-8/h2,4-5,8,16-18H,1H2,(H,12,21)(H3,11,13,14,19)/t2-,4-,5-,8-/m1/s1

Synonyms: 8-Mercaptoguanosine; 8-SH-Guo; 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-mercapto-1H-purin-6(9H)-one; 7,8-Dihydro-8-thioxoguanosine; 8-Mercapto-7,8-dihydroguanosin; 8-Tio-Guanosine; Guanosine, 8-mercapto-; NSC 79216; SQ 12760

1-(a-D-Ribofuranosyl)uracil

Description: 1-(α-D-Ribofuranosyl)uracil is a Uridine, encapsulating an indispensable role in the metabolic processes of carbohydrate derivatives.

CAT: BRP-01862

CAS: 3258-07-9

MF: C9H12N2O6

MF: 244.20

Purity: ≥97% by HPLC

Appearance: White to Off-white Powder to Crystalline Powder

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Storage: Store at 2-8°C

Density: 1.674±0.06 g/cm3 (Predicted)

Melting Point: 202 °C

InChIKey: DRTQHJPVMGBUCF-JBBNEOJLSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8+/m1/s1

Synonyms: alpha-D-Uridine; 1-(α-D-ribofuranosyl)uracil; 1-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-α-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione; Uracil, 1-α-D-ribofuranosyl-; α-D-Uridine; α-Uridine

N4-Acetyl-2'-O-tert-butyldimethylsilylcytidine

Description: N4-Acetyl-2'-O-tert-butyldimethylsilylcytidine, a formidable chemical compound adept at thwarting RNA viruses, hepatitis C virus included, is a crucial intermediary in the creation of novel nucleotide analogs with the power to curtail RNA replication and viral dissemination. This multifaceted agent is indispensable in the pursuit of new curative medicines designed to counter one of the greatest threats to global health, making it an indispensable cornerstone in modern drug discovery and biomedical inquiry.

CAT: BRP-01864

CAS: 401812-97-3

MF: C17H29N3O6Si

MF: 399.51

Purity: ≥97% by HPLC

Appearance: White to Off-white Powder

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Storage: Store at RT

Density: 1.28±0.1 g/cm3

InChIKey: FFPMJMDVFALXLQ-NMFUWQPSSA-N

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O[Si](C)(C)C(C)(C)C

IUPAC Name: N-[1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C17H29N3O6Si/c1-10(22)18-12-7-8-20(16(24)19-12)15-14(13(23)11(9-21)25-15)26-27(5,6)17(2,3)4/h7-8,11,13-15,21,23H,9H2,1-6H3,(H,18,19,22,24)/t11-,13-,14-,15-/m1/s1

Synonyms: 2'-TBDMS-Ac-rC; 2'-O-tert-butyldimethylsilyl-N4-Acetyl-cytidine; N-Acetyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]cytidine; N-Acetyl-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine

2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine

Description: 2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine, a vital reagent in the biomedical sector, holds immense significance for synthesizing diverse antiviral medications. Its unparalleled structure and mechanism of action contribute significantly to combating viral infections like hepatitis C and HIV.

CAT: BRP-01865

CAS: 182007-86-9

MF: C20H33N5O6Si

MF: 467.59

Purity: 96%

Appearance: White to Off-white Powder

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Storage: Store at RT

Density: 1.37±0.1 g/cm3 (Predicted)

InChIKey: HKUCCPHGYWSUOP-XWXWGSFUSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)O[Si](C)(C)C(C)(C)C

IUPAC Name: N-[9-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C20H33N5O6Si/c1-10(2)16(28)23-19-22-15-12(17(29)24-19)21-9-25(15)18-14(13(27)11(8-26)30-18)31-32(6,7)20(3,4)5/h9-11,13-14,18,26-27H,8H2,1-7H3,(H2,22,23,24,28,29)/t11-,13-,14-,18-/m1/s1

Synonyms: 2'-TBDMS-ibu-rG; 2'-O-TBDMS-rG(ib); 2'-O-(tert-Butyldimethylsilyl)-N-isobutyrylguanosine; Guanosine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-; 2'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-N-isobutyrylguanosine; 2'-O-[(1,1-Dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine

O6-Methylguanosine

Description: It is a guanine derivative that acts as a modulator of GTPases and modulator-resistant enzymes.

CAT: BRP-01866

CAS: 7803-88-5

MF: C11H15N5O5

MF: 297.27

Purity: ≥95%

Appearance: White to Pale Yellow Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.98±0.1 g/cm3 (Predicted)

Melting Point: 120 °C

Boiling Point: 721.0±70.0 °C at 760 mmHg

InChIKey: IXOXBSCIXZEQEQ-KQYNXXCUSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Very Slightly), Water (Slightly)

CanonicalSMILES: COC1=NC(=NC2=C1N=CN2C3C(C(C(O3)CO)O)O)N

IUPAC Name: (2R,3R,4S,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7-,10-/m1/s1

Synonyms: 6-O-Methylguanosine; 2-Amino-6-methoxy-9-β-D-ribofuranosyl-9H-purine; 2-Amino-6-methoxypurine Ribonucleoside; 6-Methoxy-9-β-D-ribofuranosyl-9H-purin-2-amine; NSC 66381; O-Methylguanosine; (2R,3R,4S,5R)-2-(2-Amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

9-Ribofuranosyl-9H-Purine-6-thiol

Description: 9-Ribofuranosyl-9H-Purine-6-thiol, utilized as an antiviral therapy to hinder viral replication, has been demonstrated to treat viral infections including, but not limited to, Hepatitis B and HIV. Its selectivity enables the targeted impact on infected CD4 T-helper cells, subsequently leading to a decrease of the viral load while simultaneously heightening the CD4 cell count.

CAT: BRP-01867

CAS: 4988-64-1

MF: C10H12N4O4S

MF: 284.29

Purity: ≥97% by HPLC

Appearance: Solid

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Density: 2.02±0.1 g/cm3

Boiling Point: 714.7±70.0°C at 760 mmHg

InChIKey: NKGPJODWTZCHGF-VTHZCTBJSA-N

CanonicalSMILES: C1=NC(=S)C2=C(N1)N(C=N2)C3C(C(C(O3)CO)O)O

IUPAC Name: 9-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione

InChI: InChI=1S/C10H12N4O4S/c15-1-4-6(16)7(17)10(18-4)14-3-13-5-8(14)11-2-12-9(5)19/h2-4,6-7,10,15-17H,1H2,(H,11,12,19)/t4-,6-,7-,10?/m1/s1

Synonyms: 9H-Purine-6-thiol, 9-ribofuranosyl-; 6H-Purine-6-thione, 3,9-dihydro-9-D-ribofuranosyl-; 6-Mercapto-9β-D-ribofuranosyl-9H-purine; 9-(D-Ribofuranosyl)-3,9-dihydro-6H-purine-6-thione; 9-(D-ribofuranosyl)-9H-purine-6-thiol

Related CAS: 574-25-4 (β-D-configuration)