Nucleosides - RNA / BOC Sciences

3-(3-Amino-3-carboxypropyl)pseudouridine (BRP-02144)

Description: It is a metabolite of Uridine, a nucleoside, which is widely distributed in nature. Uridine is one of the four basic components of RNA.

CAT: BRP-02144

MF: C13H19N3O8

MF: 345.31

Purity: ≥95%

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8 °C

Density: 1.6±0.1 g/cm3

Symbol: acp3ψ

InChIKey: ZHENYVBBFCVMEV-BKLVVQOLSA-N

CanonicalSMILES: C1=C(C(=O)N(C(=O)N1)CCC(C(=O)O)N)C2C(C(C(O2)CO)O)O

IUPAC Name: 2-amino-4-[5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxo-1H-pyrimidin-3-yl]butanoic acid

InChI: InChI=1S/C13H19N3O8/c14-6(12(21)22)1-2-16-11(20)5(3-15-13(16)23)10-9(19)8(18)7(4-17)24-10/h3,6-10,17-19H,1-2,4,14H2,(H,15,23)(H,21,22)/t6?,7-,8-,9-,10+/m1/s1

Synonyms: 2-amino-4-(5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)butanoic acid

5-(Carboxyhydroxymethyl)-2'-O-methyluridine methyl ester (BRP-02145)

Description: 5-(Carboxyhydroxymethyl)-2'-O-methyluridine methyl ester is a modified nucleoside with enhanced stability and unique functional properties. It is valuable in the fields of RNA therapeutics, biochemical research, and synthetic biology due to its ability to resist enzymatic degradation and engage in specific biochemical interactions. This nucleoside helps in advancing the understanding of RNA modifications and the development of novel RNA-based treatments.

CAT: BRP-02145

CAS: 2450329-71-0

MF: C13H18N2O9

MF: 346.29

Size	Price	Stock	Quantity
--	--	--

Inquiry

Density: 1.58±0.1 g/cm3

Symbol: mchm5Um

InChIKey: OUUYMMOUHMVFLU-VDZCSFMGSA-N

CanonicalSMILES: COC1C(C(OC1N2C=C(C(=O)NC2=O)C(C(=O)OC)O)CO)O

IUPAC Name: methyl 2-hydroxy-2-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]acetate

InChI: InChI=1S/C13H18N2O9/c1-22-9-8(18)6(4-16)24-11(9)15-3-5(7(17)12(20)23-2)10(19)14-13(15)21/h3,6-9,11,16-18H,4H2,1-2H3,(H,14,19,21)/t6-,7?,8-,9-,11-/m1/s1

Synonyms: Methyl 2-Hydroxy-2-(1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetate

5-Methoxycarbonylmethyl-2-thio-2'-O-methyluridine (BRP-02146)

Description: 5-Methoxycarbonylmethyl-2-thio-2'-O-methyluridine is a modified nucleoside with enhanced stability and unique functional properties due to its 2'-O-methyl, 2-thio, and 5-methoxycarbonylmethyl modifications. It is valuable in RNA therapeutics, biochemical research, and synthetic biology, helping to advance the understanding of RNA modifications and the development of novel RNA-based treatments.

CAT: BRP-02146

MF: C13H18N2O7S

MF: 346.36

Size	Price	Stock	Quantity
--	--	--

Inquiry

Symbol: mcm5s2Um

InChIKey: MRMYSUGDGJYWIN-UGKPPGOTSA-N

IUPAC Name: methyl 2-(1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetate

InChI: InChI=1S/C13H18N2O7S/c1-20-8(17)3-6-4-15(13(23)14-11(6)19)12-10(21-2)9(18)7(5-16)22-12/h4,7,9-10,12,16,18H,3,5H2,1-2H3,(H,14,19,23)/t7-,9-,10-,12-/m1/s1

Synonyms: Methyl 1,2,3,4-tetrahydro-4-oxo-2-thioxo-1-(2-O-methyl-β-D-ribofuranosyl)-5-pyrimidineacetate; 5-Methoxycarbonylmethyl-2-thiouridine-2'-O-methyluridine; 2-Thio-5-methoxycarbonylmethyl-2'-O-methyluridine; 2'-O-Methyl-5-methoxycarbonylmethyl-2-thiouridine

7-Aminocarboxypropylwyosine (BRP-02147)

Description: 7-Aminocarboxypropylwyosine is a highly modified nucleoside found in tRNA, playing a crucial role in maintaining the accuracy and efficiency of protein synthesis. Its complex structure and specific modifications contribute to the stability and function of tRNA, highlighting its importance in translation and broader cellular processes. This nucleoside is valuable for research in biochemistry, molecular biology, and synthetic biology, offering insights into RNA modifications and their potential applications.

CAT: BRP-02147

CAS: 898543-14-1

MF: C18H24N6O7

MF: 436.42

Size	Price	Stock	Quantity
--	--	--

Inquiry

Density: 1.85±0.1 g/cm3

Boiling Point: 924.3±75.0 °C at 760 mmHg

Symbol: yW-72

InChIKey: WFCOGXPRDSFHPT-TXRSOIPOSA-N

CanonicalSMILES: CC1=C(N2C(=O)C3=C(N(C2=N1)C)N(C=N3)C4C(C(C(O4)CO)O)O)CCC(C(=O)O)N

IUPAC Name: (2S)-2-amino-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4,6-dimethyl-9-oxoimidazo[1,2-a]purin-7-yl]butanoic acid

InChI: InChI=1S/C18H24N6O7/c1-7-9(4-3-8(19)17(29)30)24-15(28)11-14(22(2)18(24)21-7)23(6-20-11)16-13(27)12(26)10(5-25)31-16/h6,8,10,12-13,16,25-27H,3-5,19H2,1-2H3,(H,29,30)/t8-,10+,12+,13+,16+/m0/s1

Synonyms: 3H-Imidazo[1,2-a]purine-7-butanoic acid, α-amino-4,9-dihydro-4,6-dimethyl-9-oxo-3-β-D-ribofuranosyl-, (αS)-; (αS)-α-Amino-4,9-dihydro-4,6-dimethyl-9-oxo-3-β-D-ribofuranosyl-3H-imidazo[1,2-a]purine-7-butanoic acid; (S)-2-amino-4-(3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4,6-dimethyl-9-oxo-4,9-dihydro-3H-imidazo[1,2-a]purin-7-yl)butanoic acid

Cyclic N6-threonylcarbamoyladenosine (BRP-02148)

Description: Cyclic N6-threonylcarbamoyladenosine (ct6A) is a highly modified nucleoside found in tRNA that plays a critical role in maintaining the accuracy and efficiency of protein synthesis. Its complex structure, involving a cyclic threonine-derived moiety attached to adenosine, contributes to the stability and proper functioning of tRNA. This modification is essential for precise codon recognition and preventing translation errors, highlighting its importance in the overall process of gene expression and cellular function. Research into ct6A and other tRNA modifications provides valuable insights into the mechanisms of translation and has potential applications in genetic, molecular biology, and synthetic biology fields.

CAT: BRP-02148

CAS: 1415901-62-0

MF: C15H18N6O7

MF: 394.34

Size	Price	Stock	Quantity
--	--	--

Inquiry

Density: 2.04±0.1 g/cm3

Boiling Point: 728.5±70.0 °C at 760 mmHg

Symbol: ct6A

InChIKey: NIMLOKNRDJCYPO-DWVDDHQFSA-N

CanonicalSMILES: CC(C1C(=O)OC(=N1)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O)O

IUPAC Name: (4S)-2-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]-4-[(1R)-1-hydroxyethyl]-4H-1,3-oxazol-5-one

InChI: InChI=1S/C15H18N6O7/c1-5(23)7-14(26)28-15(19-7)20-11-8-12(17-3-16-11)21(4-18-8)13-10(25)9(24)6(2-22)27-13/h3-7,9-10,13,22-25H,2H2,1H3,(H,16,17,19,20)/t5-,6-,7+,9-,10-,13-/m1/s1

Synonyms: N-[(4S)-4,5-Dihydro-4-[(1R)-1-hydroxyethyl]-5-oxo-2-oxazolyl]adenosine; N6-cyclicthreonyladenosine; cyclic t(6)A; ct(6)A; Cyclic N(6)-threonylcarbamoyladenosine; Cyclic threonylcarbamoyladenosine; cyclic N(6)-(L-threonylcarbamoyl)adenosine; N-{(4S)-4-[(1R)-1-hydroxyethyl]-5-oxo-1,3-oxazolidin-2-ylidene}adenosine; cyclic t6A

Xylitol-[d7] (BRP-02150)

Description: Xylitol-[d7] is deuterium labelled Xylitol, which is a lower-calorie alternative to table sugar. Studies have shown that xylitol chewing gum can benefit acute otitis media. Xylitol is categorized by the U.S. FDA as a food additive.

CAT: BRP-02150

MF: C5H5D7O5

MF: 159.19

Purity: 98%; 99.1% atom D

Appearance: White Solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at -20 °C

Melting Point: 92-95 °C

Shipping: Room temperature.

InChIKey: HEBKCHPVOIAQTA-PZQXHKSTSA-N

Synthesis Conditions: We recommend only using fast deprotecting amidites with this product due to the mild cleavage and deprotection conditions.

Deprotection Conditions: Cleave and deprotect in concentrated NH4OH for 1 hour at 60°C (after 1 hour at 60°C; degradation of product may occur).

Solubility: Soluble in Water (Slightly)

CanonicalSMILES: OCC(O)C(O)C(O)CO

IUPAC Name: (2R,3r,4S)-pentane-d7-1,2,3,4,5-pentaol

InChI: InChI=1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4+,5+/i1D2,2D2,3D,4D,5D

Synonyms: Xylitol-1,1,2,3,4,5,5-d7; (2R,3R,4S)-(D7)pentane-1,2,3,4,5-pentol; DL-Xylitol-d7; meso-Xylitol-d7; xylo-Pentitol-d7

Related CAS: 87-99-0 (unlabelled)