Nucleosides

2'-Modified Nucleosides
(290/290)
3'-Modified Nucleosides
(157/157)
5'-Modified Nucleosides
(237/237)
Anhydro-Nucleosides
(13/13)
Arabinonucleosides
(34/34)
Base Protected Nucleosides
(224/224)
Halogen Nucleosides
(135/135)
L-Nucleosides
(18/18)
Other Nucleosides
(77/77)
Other Protected Nucleosides
(23/23)
Ribonucleosides
(11/11)
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4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine

Description: 4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine, a formidable antiviral compound widely employed in biomedical research, exhibits remarkable efficacy against notorious viral afflictions like HIV and hepatitis C. Via robust inhibition of viral replication, this nucleoside analogue serves as a valuable instrument in drug discovery endeavors and holds immense potential as an antiviral therapeutic agent of choice, propelling advancements in the realm of antiviral treatment development.
CAT: BRP-01972
CAS: 173379-73-2
MF: C9H10FN5O5
MF: 287.20
Purity: ≥95%
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Storage: Store at 2-8 °C
InChIKey: SNWCOSVWPQSOEU-XZMZPDFPSA-N
CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)(CO)N=[N+]=[N-])O)F
IUPAC Name: 1-[(2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C9H10FN5O5/c10-5-6(18)9(3-16,13-14-11)20-7(5)15-2-1-4(17)12-8(15)19/h1-2,5-7,16,18H,3H2,(H,12,17,19)/t5-,6-,7+,9+/m0/s1
Synonyms: 4'-Azido-2'-deoxy-2'-fluoro-beta-D-arabinouridine; 4'-Azido-2'-deoxy-2'-fluoro-beta-D-arabinoribofuranosyl uracil; 2,4(1H,3H)-Pyrimidinedione, 1-[4-C-azido-2-deoxy-2-fluoro-beta-D-arabinofuranosyl]-; 1-[(2R,3S,4R,5R)-5-Azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione

4'-C-Azido-2'-deoxy-2'-fluoro-uridine

Description: 4'-C-Azido-2'-deoxy-2'-fluoro-uridine, an indispensable compound within the biomedical field, showcases immense potential as an antiviral agent, specifically combating the challenging hepatitis B and C viruses. By virtue of its distinct chemical composition, this compound effectively hinders viral replication through its precise targeting of viral RNA synthesis.
CAT: BRP-01973
CAS: 1158728-80-3
MF: C9H10FN5O5
MF: 287.20
Purity: ≥95%
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InChIKey: SNWCOSVWPQSOEU-JVZYCSMKSA-N
CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)(CO)N=[N+]=[N-])O)F
IUPAC Name: 1-[(2R,3R,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C9H10FN5O5/c10-5-6(18)9(3-16,13-14-11)20-7(5)15-2-1-4(17)12-8(15)19/h1-2,5-7,16,18H,3H2,(H,12,17,19)/t5-,6+,7-,9-/m1/s1
Synonyms: 1-((2R,3R,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Deoxy-2'-fluoro-4'-azidouridine; 4'-C-Azido-2'-deoxy-2'-fluorouridine

4'-Azido-3'-O-benzoyl-5'-O-(m-chlorobenzoyl)-2'-deoxy-2'-fluoro-beta-D-arabinouridine

Description: 4'-Azido-3'-O-benzoyl-5'-O-(m-chlorobenzoyl)-2'-deoxy-2'-fluoro-beta-D-arabinouridine is an influential antiviral compound, specifically designed to impede the replication of targeted viruses like HIV and herpes simplex virus (HSV). Its inherent capability to disrupt viral DNA research and development manifesting in restraining viral propagation.
CAT: BRP-01975
CAS: 1333126-30-9
MF: C23H17ClFN5O7
MF: 529.86
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: ZSOIOSPOWYBGRD-PABYOWBDSA-N
CanonicalSMILES: C1=CC=C(C=C1)C(=O)OC2C(C(OC2(COC(=O)C3=CC(=CC=C3)Cl)N=[N+]=[N-])N4C=CC(=O)NC4=O)F
IUPAC Name: ((2R,3R,4S,5R)-2-azido-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-2-yl)methyl 3-chlorobenzoate
InChI: InChI=1S/C23H17ClFN5O7/c24-15-8-4-7-14(11-15)20(32)35-12-23(28-29-26)18(36-21(33)13-5-2-1-3-6-13)17(25)19(37-23)30-10-9-16(31)27-22(30)34/h1-11,17-19H,12H2,(H,27,31,34)/t17-,18
Synonyms: 1-[4-Azido-3-O-benzoyl-5-O-(3-chlorobenzoyl)-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)uracil; 4'-Azido-3'-O-benzoyl-5'-O-(m-chlorobenzyl)-2'-deoxy-2'-fluoro-β-Darabinouridine; [(2R,3R,4S,5R)-2-Azido-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-4-fluorotetrahydro-2-furanyl]methyl 3-chlorobenzoate

N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine

Description: N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine, a biomedical product that is extensively studied for the treatment of various cancer types, boasts selective targeting properties allowing it to act as a candidate for cancer therapy. This antiviral and antitumor drug functions by inhibiting DNA replication, contributing to its efficacy in treating cancer. Breast cancer, lung cancer, and leukemia are just some of the many debilitating conditions that this therapy has impressive potential against.
CAT: BRP-01977
CAS: 159414-98-9
MF: C32H32FN3O7
MF: 589.61
Purity: ≥98% by HPLC
Appearance: White to Off-white Crystalline Powder
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Storage: Store at 2-8°C
Density: 1.31±0.1 g/cm3 (Predicted)
InChIKey: JIFNUYITABZZQS-PYYPWFDZSA-N
CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)F
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C32H32FN3O7/c1-20(37)34-27-17-18-36(31(39)35-27)30-28(33)29(38)26(43-30)19-42-32(21-7-5-4-6-8-21,22-9-13-24(40-2)14-10-22)23-11-15-25(41-3)16-12-23/h4-18,26,28-30,38H,19H2,1-3H3,(H,34,35,37,39)/t26-,28-,29-,30-/m1/s1
Synonyms: 5'-O-DMT-N4-acetyl-2'-Fluoro-2'-deoxycytidine; 5'-DMT-2'-F-Ac-dC; 2'-Fluoro-5'-O-DMT-N4-acetyl-cytidine; N4-Acetyl-5'-O-DMT-2'-fluoro-2'-deoxycytidine; N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-cytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluorocytidine; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxycytidine; DMT-2'-F-Ac-dC; 5'-O-DMTr-2'-F-dC(Ac)

N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-guanosine

Description: N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-guanosine (N2-iBd2FG) is a remarkable biochemical compound extensively employed to facilitate nucleic acid synthesis. This distinctive compound is notably used in the strategic formulation of pharmacological interventions directed towards studying viral afflictions, exemplified by influenza and human immunodeficiency virus (HIV).
CAT: BRP-01978
CAS: 144089-96-3
MF: C35H36FN5O7
MF: 657.69
Purity: ≥95%
Appearance: White to light yellow powder
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Storage: Store at 2-8 °C
Density: 1.38±0.1 g/cm3
InChIKey: QQQXVSXVBFQISZ-UNVYQVKTSA-N
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)F
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C35H36FN5O7/c1-20(2)31(43)39-34-38-30-28(32(44)40-34)37-19-41(30)33-27(36)29(42)26(48-33)18-47-35(21-8-6-5-7-9-21,22-10-14-24(45-3)15-11-22)23-12-16-25(46-4)17-13-23/h5-17,19-20,26-27,29,33,42H,18H2,1-4H3,(H2,38,39,40,43,44)/t26-,27-,29-,33-/m1/s1
Synonyms: 5'-O-DMT-N2-ibu-2'-F-dG; N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 5'-O-(4,4'-Dimethoxytrityl)-2'-fluoro-N2-isobutyryl-2'-deoxyguanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)guanosine; 5'-O-DMT-N2-isobutyryl-2'-fluoro-2'-deoxyguanosine; DMT-2'-F-dGiBu; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluoro-N-isobutyrylguanosine; 5'-O-DMTr-2'-F-dG(iBu); 5'-O-(4,4'-dimethoxytrityl)-N2-isobutyryl-2'-fluoro-2'-deoxyguanosine; N2-iBu-DMT-2'-F-dG; 2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine

2'-Deoxy-5'-O-DMT-2'-fluoro-uridine

Description: It is used for RNA synthesis and nucleoside modification.
CAT: BRP-01979
CAS: 146954-74-7
MF: C30H29FN2O7
MF: 548.56
Purity: ≥95%
Appearance: White to Off-white Crystalline Powder
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Storage: Store at -20°C
Density: 1.38±0.1 g/cm3(Predicted)
InChIKey: CSSFZSSZXOCCJB-YULOIDQLSA-N
Solubility: Soluble in DMSO (10 mM)
CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)F)O
IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C30H29FN2O7/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-27(35)26(31)28(40-24)33-17-16-25(34)32-29(33)36/h3-17,24,26-28,35H,18H2,1-2H3,(H,32,34,36)/t24-,26-,27-,28-/m1/s1
Synonyms: 2'-F-5'-O-DMT-2'-dU; 5'-O-DMT-2'-fluoro-2'-deoxy-D-uridine; 2'-Fluoro-5'-O-DMT-uridine; 2'-Deoxy-5'-O-DMT-2'-fluoro-D-uridine; 5'-O-DMT-2'-fluoro-2'-deoxyuridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-DMTr-2'-F-dU

5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine

Description: 5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine boasts a promising pharmacological arsenal to combat a range of viral infections. With virucidal efficacy that targets the DNA replication machinery of several virus strains, the drug holds considerable therapeutic potential for cases of hepatitis B and C, as well as herpes and shingles. Furthermore, its anti-neoplastic properties make it a noteworthy exploratory tool for certain types of cancer treatment.
CAT: BRP-01980
CAS: 146954-77-0
MF: C37H34FN3O7
MF: 651.68
Purity: ≥98% by HPLC
Appearance: White powder
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Storage: Store at 2-8 °C
Density: 1.3±0.1 g/cm3
InChIKey: RAIBEZUVTIPFOJ-NHASGABXSA-N
CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=NC5=O)NC(=O)C6=CC=CC=C6)F)O
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C37H34FN3O7/c1-45-28-17-13-26(14-18-28)37(25-11-7-4-8-12-25,27-15-19-29(46-2)20-16-27)47-23-30-33(42)32(38)35(48-30)41-22-21-31(40-36(41)44)39-34(43)24-9-5-3-6-10-24/h3-22,30,32-33,35,42H,23H2,1-2H3,(H,39,40,43,44)/t30-,32-,33-,35-/m1/s1
Synonyms: 5'-O-(4,4'-dimethoxytrityl)-N4-benzoyl-2'-fluoro-2'-deoxycytidine; N4-Bz-DMT-2'-F-dC; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-cytidine; N4-Benzoyl-5'-O-DMT-2'-fluoro-2'-deoxycytidine; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine; 5'-O-DMTr-2'-F-dC(Bz); 5'-DMT-2'-F-Bz-dC; 5'-O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-fluoro-2'-deoxyadenosine; N-{1-{5-O-[bis-(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-D-arabinofuranosyl}-1,2-dihydro-2-oxo-4-pyrimidinyl}-benzamide; N-benzoyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-deoxy-2'-fluoro-Cytidine; 5'-O-DMT-N4-Bz-2'-F-dC

N4-Acetyl-2'-deoxy-2'-fluorocytidine

Description: N4-Acetyl-2'-deoxy-2'-fluorocytidine is an efficacious antiviral compound, finding extensive application within the biomedical sector for studying viral infections such as hepatitis B, hepatitis C and HIV by impeding viral replication.
CAT: BRP-01981
CAS: 159414-97-8
MF: C11H14FN3O5
MF: 287.24
Purity: ≥97% by HPLC
Appearance: White to Off-white Powder
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Storage: Store at -20°C
Density: 1.68±0.1 g/cm3 (Predicted)
InChIKey: NLXVKEFNBVLDLD-PEBGCTIMSA-N
CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)F
IUPAC Name: N-[1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C11H14FN3O5/c1-5(17)13-7-2-3-15(11(19)14-7)10-8(12)9(18)6(4-16)20-10/h2-3,6,8-10,16,18H,4H2,1H3,(H,13,14,17,19)/t6-,8-,9-,10-/m1/s1
Synonyms: N4-Acetyl-2'-deoxy-2'-fluoro-D-cytidine; N4-Acetyl-2'-fluoro-2'-deoxycytidine; N4-Ac-2'-F-dC; N-Acetyl-2'-deoxy-2'-fluorocytidine; N-(1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide; 2'-F-dC(Ac)

N4-Benzoyl-2'-deoxy-2'-fluorocytidine

Description: N4-Benzoyl-2'-deoxy-2'-fluorocytidine, an antiviral medication utilized in the treatment of HIV and HBV infections, is a potent inhibitor that thwarts transcription and reproduction of the virus. Due to its high selectivity for viral polymerases, it proficiently targets the afflicted cells, leaving intact ones unharmed. This nucleoside analogue reverse transcriptase blocking agent sustains its efficacy in neutralizing the viruses, shortly providing immense relief to the patients.
CAT: BRP-01982
CAS: 146954-76-9
MF: C16H16FN3O5
MF: 349.31
Purity: ≥97% by HPLC
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Storage: Store at 2-8 °C
Density: 1.56±0.1 g/cm3 (Predicted)
InChIKey: RHCOKFXBQWNMHE-BPGGGUHBSA-N
CanonicalSMILES: C1=CC=C(C=C1)C(=O)NC2=NC(=O)N(C=C2)C3C(C(C(O3)CO)O)F
IUPAC Name: N-[1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C16H16FN3O5/c17-12-13(22)10(8-21)25-15(12)20-7-6-11(19-16(20)24)18-14(23)9-4-2-1-3-5-9/h1-7,10,12-13,15,21-22H,8H2,(H,18,19,23,24)/t10-,12-,13-,15-/m1/s1
Synonyms: 2'-F-dC(Bz); N-(1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide; Cytidine, N-benzoyl-2'-deoxy-2'-fluoro-; N-Benzoyl-2'-deoxy-2'-fluorocytidine; N4-Bz-2'-F-dC

N6-Benzoyl-2'-deoxy-2'-fluoroadenosine

Description: N6-Benzoyl-2'-deoxy-2'-fluoroadenosine is a nucleoside analog where a benzoyl group is attached to the N6 position of the adenine base and a fluorine atom is substituted at the 2' position of the deoxyribose sugar. This modification is typically explored in medicinal chemistry to alter the nucleoside's interaction with enzymes involved in nucleic acid synthesis or to improve its pharmacokinetic properties. Such modifications are aimed at developing compounds with potential therapeutic applications, including antiviral or anticancer activities, by enhancing potency, selectivity, or stability.
CAT: BRP-01983
CAS: 136834-20-3
MF: C17H16FN5O4
MF: 373.34
Purity: ≥98% by HPLC
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Storage: Store at 2-8 °C
Density: 1.67±0.1 g/cm3(Predicted)
InChIKey: HLJZTLWDAQVZBU-YAMOITTJSA-N
CanonicalSMILES: C1=CC=C(C=C1)C(=O)NC2=NC=NC3=C2N=CN3C4C(C(C(O4)CO)O)F
IUPAC Name: N-[9-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C17H16FN5O4/c18-11-13(25)10(6-24)27-17(11)23-8-21-12-14(19-7-20-15(12)23)22-16(26)9-4-2-1-3-5-9/h1-5,7-8,10-11,13,17,24-25H,6H2,(H,19,20,22,26)/t10-,11-,13-,17-/m1/s1
Synonyms: N6-Benzoyl-2'-fluoro-2'-deoxyadenosine; 2'-F-dA(Bz); Bz-2'-F-dA; Adenosine, N-benzoyl-2'-deoxy-2'-fluoro-; N-Benzoyl-2'-deoxy-2'-fluoroadenosine

N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine

Description: N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine is a pivotal compound extensively utilized in studying diverse afflictions such as cancer and viral infections.
CAT: BRP-01984
CAS: 136834-21-4
MF: C38H34FN5O6
MF: 675.72
Purity: 98%
Appearance: White to off-white powder
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Storage: Store at 2-8°C
Density: 1.35±0.1 g/cm3(Predicted)
InChIKey: DDOOVEXTSRBCMU-VYUOYPLNSA-N
CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)F)O
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C38H34FN5O6/c1-47-28-17-13-26(14-18-28)38(25-11-7-4-8-12-25,27-15-19-29(48-2)20-16-27)49-21-30-33(45)31(39)37(50-30)44-23-42-32-34(40-22-41-35(32)44)43-36(46)24-9-5-3-6-10-24/h3-20,22-23,30-31,33,37,45H,21H2,1-2H3,(H,40,41,43,46)/t30-,31-,33-,37-/m1/s1
Synonyms: N6-Bz-2'-deoxy-5'-O-DMT-2'-fluoroadenosine; DMT-2'-F-Bz-dA; N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-adenosine; N6-Benzoyl-5'-O-DMT-2'-fluoro-2'-deoxyadenosine; 5'-O-DMTr-2'-F-dA(Bz); N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoroadenosine; 5'-O-(4,4'-dimethoxytrityl)-N6-benzoyl-2'-fluoro-2'-deoxyadenosine; N6-Bz-DMT-2'-F-dA; 5'-O-DMT-N6-Bz-2'-fluoro-2'-deoxyadenosine

2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine

Description: 2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine, a remarkable and influential compound, is extensively utilized in the realm of biomedical research. Its widespread application lies in investigating the impeding effect it manifests on viral RNA synthesis across diverse viral infections. This nucleoside analog showcases auspicious efficacy against select DNA and RNA viruses, thereby rendering it an invaluable asset in the arena of antiviral drug development and investigations pertaining to virology.
CAT: BRP-01985
CAS: 80681-25-0
MF: C14H18FN5O5
MF: 355.33
Purity: ≥97% by HPLC
Appearance: White to Off-white Powder
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Storage: Store at 2-8 °C
Density: 1.78±0.1 g/cm3 (Predicted)
InChIKey: SLHADUUWJSVYGQ-HTFXMJNNSA-N
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)F
IUPAC Name: N-[9-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C14H18FN5O5/c1-5(2)11(23)18-14-17-10-8(12(24)19-14)16-4-20(10)13-7(15)9(22)6(3-21)25-13/h4-7,9,13,21-22H,3H2,1-2H3,(H2,17,18,19,23,24)/t6-,7-,9-,13-/m1/s1
Synonyms: 2'-Deoxy-N2-isobutyryl-2'-fluoroguanosine; N2-Isobutyryl-2'-fluoro-deoxyguanosine; 2'-Deoxy-2'-fluoro-N2-isobutyryl-D-guanosine; 2'-Fluoro-N2-isobutyryl-2'-deoxyguanosine; N-(9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 2'-F-dG(iBu)

N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine

Description: N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine, a compound highly regarded in the biomedical industry, showcases exceptional potential as a robust antiviral agent, with a focused application on combatting viral infections. Through its ability to impede viral replication and thwart the dissemination of viruses within the body, this compound represents a significant advancement in the treatment of specific diseases caused by viral infections. With its precise mode of action and remarkable therapeutic prospects, it emerges as a pivotal instrument for the development of groundbreaking antiviral medications within the domain of biomedicine.
CAT: BRP-01993
CAS: 182495-82-5
MF: C38H36FN3O7
MF: 665.72
Purity: >98%
Appearance: White to light yellow powder
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Density: 1.29±0.1 g/cm3
InChIKey: CWIJQSZZNFLZTM-DHKUXYTCSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)F
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C38H36FN3O7/c1-24-22-42(37(45)41-34(24)40-35(44)25-10-6-4-7-11-25)36-32(39)33(43)31(49-36)23-48-38(26-12-8-5-9-13-26,27-14-18-29(46-2)19-15-27)28-16-20-30(47-3)21-17-28/h4-22,31-33,36,43H,23H2,1-3H3,(H,40,41,44,45)/t31-,32-,33-,36-/m1/s1
Synonyms: 5'-O-DMT-N4-Benzoyl-2'-Fluoro-5-methyl-2'-deoxycytidine; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methyl-D-cytidine; N4-Benzoyl-5'-O-DMT-2'-fluoro-5-methyl-2'-deoxycytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-5-methylcytidine; 5'-O-DMT-2'-F-5-Me-dC(Bz)

N4-Phenoxyacetyl-2'-fluoro-2'-deoxycytidine

Description: N4-Phenoxyacetyl-2'-Fluoro-2'-deoxycytidine, a newly discovered antiviral agent, boasts an impressive range of applications including the treatment of hepatitis B, C and HIV infections. Functioning through suppression of viral replication and significantly reducing the viral load in infected patients, this drug exhibits substantial promise in preliminary clinical studies and may be pivotal in the continued development of antiviral treatments.
CAT: BRP-01994
MF: C17H18FN3O6
MF: 379.34
Purity: ≥97% by HPLC
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InChIKey: DJTFJSQWEAQCIZ-RAEVTNRLSA-N
IUPAC Name: N-(1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)-2-phenoxyacetamide
InChI: InChI=1S/C17H18FN3O6/c18-14-15(24)11(8-22)27-16(14)21-7-6-12(20-17(21)25)19-13(23)9-26-10-4-2-1-3-5-10/h1-7,11,14-16,22,24H,8-9H2,(H,19,20,23,25)/t11-,14-,15-,16-/m1/s1
Synonyms: N4-PAc-2'-F-dC; N4-PAc-2'-Fluoro-2'-deoxycytidine

Gemcitabine Impurity C (EP)

Description: Gemcitabine Impurity C is a metabolite of Gemcitabine in human plasma.
CAT: BRP-01995
CAS: 114248-23-6
MF: C9H10F2N2O5
MF: 264.19
Purity: ≥97% by HPLC
Appearance: White to Off-White Solid
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Storage: Store at -20°C
Density: 1.69±0.1 g/cm3 (Predicted)
Melting Point: 146-150°C
InChIKey: FIRDBEQIJQERSE-QPPQHZFASA-N
Solubility: Soluble in Methanol (Slightly), Water (Very Slightly, Heated)
CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)(F)F
IUPAC Name: 1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C9H10F2N2O5/c10-9(11)6(16)4(3-14)18-7(9)13-2-1-5(15)12-8(13)17/h1-2,4,6-7,14,16H,3H2,(H,12,15,17)/t4-,6-,7-/m1/s1
Synonyms: 2',2'-Difluoro-2'-deoxyuridine; 2'-Deoxy-2',2'-difluorouridine; 2',2'-Difluorodeoxyuridine; 1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-Deoxy-2,2-difluoro-beta-D-erythro-pentofuranosyl)pyrimidin-2,4(1H,3H)-dione; Gemcitabine EP Impurity C

2'-Deoxy-2'-fluoroguanosine

Description: It is an influenza viral polymerase inhibitor like Ribavirin, used as an antiviral drug against avian (H5N1) influenza virus.
CAT: BRP-01996
CAS: 78842-13-4
MF: C10H12FN5O4
MF: 285.23
Purity: ≥95%
Appearance: White to Off-white Powder
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Storage: Store at -20°C
Density: 2.17±0.1 g/cm3 (Predicted)
Melting Point: 262-264°C (water)
Application: Antiviral Agents
InChIKey: UXUZARPLRQRNNX-DXTOWSMRSA-N
Solubility: Soluble in Water
CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)F)N=C(NC2=O)N
IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
InChI: InChI=1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4-,6-,9-/m1/s1
Synonyms: 2'-Fluoro Guanosine; 2'-F-2'-dG; 9-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)guanine; 2'-Fluoro-2'-deoxyguanosine; 2-Amino-9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; Guanosine, 2'-deoxy-2'-fluoro-; 2'-Fluoro-Riboguanosine
Related CAS: 1044657-61-5 (Deleted CAS) ; 1056189-43-5 (Deleted CAS)

2'-Deoxy-2'-fluorouridine

Description: It is a component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer.
CAT: BRP-01997
CAS: 784-71-4
MF: C9H11FN2O5
MF: 246.19
Purity: ≥95%
Appearance: White Crystalline Powder
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Storage: Store at 2-8°C
Density: 1.63±0.1 g/cm3 (Predicted)
Melting Point: 147.0-153.0°C
Application: Antineoplastic Agents
InChIKey: UIYWFOZZIZEEKJ-XVFCMESISA-N
Solubility: Soluble in Methanol
CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F
IUPAC Name: 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1
Synonyms: 2'-Fluoro-2'-deoxyuridine; Fioluridine; 1-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)uracil; 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione; 2'-Fluoro Uridine; 2'-F-dU; 2'-Fluoro-uridine

2'-Deoxy-2'-fluorocytidine

Description: 2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine demonstrated to inhibit Borna Disease virus replication and spread.
CAT: BRP-01998
CAS: 10212-20-1
MF: C9H12FN3O4
MF: 245.21
Purity: ≥95%
Appearance: White Solid
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Storage: Store at 2-8°C
Density: 1.82±0.1 g/cm3 (Predicted)
Melting Point: >187°C (dec.)
Boiling Point: 500.1±60.0°C (Predicted)
InChIKey: NVZFZMCNALTPBY-XVFCMESISA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)
CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)F
IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
InChI: InChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6-,7-,8-/m1/s1
Synonyms: 2'-Fluoro Cytidine; 2'-Fluoro-2'-deoxy-β-D-ribofuranosylcytosine; 2'-Fluoro-2'-deoxycytidine; NSC 529432; 4-amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2'-F-dC
Related CAS: 1820580-34-4 (hydrate)

2'-Deoxy-2'-fluoroadenosine

Description: 2'-Deoxy-2'-fluoroadenosine is a modified nucleoside where a fluorine atom is substituted at the 2' position of the ribose sugar in adenosine. This modification enhances the stability and alters the biochemical properties of the nucleoside. It is used in studying nucleotide metabolism, enzymatic reactions involving nucleosides, and exploring nucleic acid-protein interactions.
CAT: BRP-01999
CAS: 64183-27-3
MF: C10H12FN5O3
MF: 269.23
Purity: ≥95%
Appearance: White to off-white solid
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Storage: Store at -20 °C under inert atmosphere
Density: 2.01±0.1 g/cm3 (Predicted)
Melting Point: 228-231 °C
Boiling Point: 628.6±65.0 °C (Predicted)
InChIKey: ZGYYPTJWJBEXBC-QYYRPYCUSA-N
Solubility: Soluble in Acetonitrile (Slightly), Methanol (Slightly, Heated)
CanonicalSMILES: C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CO)O)F
IUPAC Name: (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
InChI: InChI=1S/C10H12FN5O3/c11-5-7(18)4(1-17)19-10(5)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1
Synonyms: 2'-Fluoro Adenosine; 2'-Fluoro-2'-deoxyadenosine; (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol; 9-(2-Fluoro-2-deoxy-beta-D-ribofuranosyl)-purin-6-amine; 9-(2-Deoxy-2-fluoro-beta-D-ribofuranosyl)adenine; 6-Amino-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine; 2'-F-dA

N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine

Description: N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine is a potent antiviral drug specifically used in the treatment of various viral infections. It exhibits remarkable activity against various DNA viruses, including herpes simplex virus and varicella-zoster virus. This product acts by inhibiting viral DNA synthesis and effectively reducing the viral load, thus aiding in the management of viral diseases.
CAT: BRP-02000
CAS: 226415-08-3
MF: C38H34FN5O6
MF: 675.71
Purity: ≥95%
Appearance: White to Off-white Crystalline Powder
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Density: 1.35±0.1 g/cm3
Boiling Point: 869.8±75.0°C at 760 mmHg
InChIKey: DDOOVEXTSRBCMU-MHHBZGPPSA-N
CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)F)O
IUPAC Name: N-[9-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C38H34FN5O6/c1-47-28-17-13-26(14-18-28)38(25-11-7-4-8-12-25,27-15-19-29(48-2)20-16-27)49-21-30-33(45)31(39)37(50-30)44-23-42-32-34(40-22-41-35(32)44)43-36(46)24-9-5-3-6-10-24/h3-20,22-23,30-31,33,37,45H,21H2,1-2H3,(H,40,41,43,46)/t30-,31+,33-,37-/m1/s1
Synonyms: 5'-O-DMT-N6-Bz-2'-F-ara-2'-dA; 5-O-(4,4'-dimethoxytrityl)-N6-benzoyl-2'-fluoro-β-D-arabinofuranosyl-2'-deoxyadenine; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxy-arabinoadenosine; 9-[2-Deoxy-5-O-(4,4'-dimethoxytrityl)-2-fluoro-beta-D-arabinofuranosyl]-N6-benzoyladenine; N-(9-((2R,3S,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; 5'-O-DMT-N6-Bz-2'-ara-F-2'-dA; N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-arabinoadenosine; 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine
* Only for research. Not suitable for any diagnostic or therapeutic use.
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