Nucleosides

2'-Modified Nucleosides
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3'-Modified Nucleosides
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5'-Modified Nucleosides
(236/236)
Anhydro-Nucleosides
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Arabinonucleosides
(34/34)
Base Protected Nucleosides
(224/224)
Halogen Nucleosides
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L-Nucleosides
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Other Nucleosides
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Other Protected Nucleosides
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Ribonucleosides
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D-Glucose-[2-13C,2-d1] (BRP-02121)

Description: Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a crucial role in photosynthesis and energy source required for cellular respiration. D-Glucose is used in various metabolic processes including the enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in type 2 diabetes mellitus detection and potentially Huntington's disease through blood-glucose analysis in type 1 diabetes mellitus.
CAT: BRP-02121
CAS: 83379-46-8
MF: C5[13C]H11DO6
MF: 182.15
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InChIKey: GZCGUPFRVQAUEE-BLIQJOKYSA-N
CanonicalSMILES: C(C(C(C(C(C=O)O)O)O)O)O
IUPAC Name: (2R,3S,4R,5R)-2-deuterio-2,3,4,5,6-pentahydroxy(2-13C)hexanal
InChI: InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1/i3+1D
Synonyms: D-[2-13C,2-2H]glucose; D-Glucose-2-13C-2-C-2H; D-Glucose-2-13C-2-C-d; D-Glucose-13C,d1; (+)-Glucose-2-13C,2-d1; Glucose-2-13C,2-d1; D-(+)-Glucose-2-13C,2-d1; D-Glucose-2-13C,2-d1
Related CAS: 50-99-7 (unlabelled)

N4-Acetyl-2'-O-methylcytidine (BRP-02123)

Description: N4-Acetyl-2'-O-methylcytidine is an innovative and scientifically advanced compound, emerging as a groundbreaking solution for studying RNA virus-induced viral afflictions. By specifically pinpointing viral enzymes or obstructing viral replication, it manifests remarkable antiviral attributes.
CAT: BRP-02123
CAS: 113886-71-8
MF: C12H17N3O6
MF: 299.28
Purity: ≥97% by HPLC
Appearance: White to Yellow Solid
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Storage: Store at -20 °C, under inert atmosphere
Density: 1.58±0.1 g/cm3 (Predicted)
Symbol: ac4Cm
InChIKey: CYDFBLGNJUNSCC-QCNRFFRDSA-N
Solubility: Soluble in Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)OC
IUPAC Name: N-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C12H17N3O6/c1-6(17)13-8-3-4-15(12(19)14-8)11-10(20-2)9(18)7(5-16)21-11/h3-4,7,9-11,16,18H,5H2,1-2H3,(H,13,14,17,19)/t7-,9-,10-,11-/m1/s1
Synonyms: Cytidine, N-acetyl-2'-O-methyl-; N4-Ac-2'-OMe-rC; N4-Acetyl-2'-O-methyl cytidine; N-Acetyl-2'-O-methylcytidine; N-(1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

N6-Threonylcarbamoyladenosine (BRP-02124)

Description: N6-Threonylcarbamoyladenosine is an indispensable bioactive compound in the biomedical sector, aiding in studying an array of malignancies, predominantly those afflicting the mammary and pulmonary tissues.
CAT: BRP-02124
CAS: 24719-82-2
MF: C15H20N6O8
MF: 412.36
Purity: ≥98% by HPLC
Appearance: White to beige soild
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Storage: Store at -20 °C, under inert atmosphere
Density: 1.96±0.1 g/cm3
Symbol: t6A
InChIKey: UNUYMBPXEFMLNW-DWVDDHQFSA-N
Solubility: Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly, Heated)
CanonicalSMILES: CC(C(C(=O)O)NC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O)O
IUPAC Name: (2S,3R)-2-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]carbamoylamino]-3-hydroxybutanoic acid
InChI: InChI=1S/C15H20N6O8/c1-5(23)7(14(26)27)19-15(28)20-11-8-12(17-3-16-11)21(4-18-8)13-10(25)9(24)6(2-22)29-13/h3-7,9-10,13,22-25H,2H2,1H3,(H,26,27)(H2,16,17,19,20,28)/t5-,6-,7+,9-,10-,13-/m1/s1
Synonyms: L-Threonine, N-[[(9-b-D-ribofuranosyl-9H-purin-6-yl) amino]carbonyl]-; N-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}adenosine; N-[(9-beta-D-ribofuranosylpurin-6-yl)carbamoyl]-L-threonine; N-[[(9-β-D-Ribofuranosyl-9H-purin-6-yl)amino]carbonyl]-L-threonine; N-(6-Nebularinylcarbamoyl)threonine; N-(6-Purinylcarbamoyl)-L-threonine riboside; N-[(9-β-D-Ribofuranosyl-9H-purin-6-yl)carbamoyl]-L-threonine; N-[N-(9-β-D-Ribofuranosylpurin-6-yl)carbamoyl]threonine; N6-(N-Threonylcarbonyl)adenosine; N6-Carbamoylthreonyl adenosine; t6-Adenosine

N4-Acetylcytidine (BRP-02125)

Description: N4-Acetylcytidine is an extraordinary bioactive compound, widely used in the research of viral afflictions. It can unyieldingly thwart viral replication and diminish the onerous viral burden.
CAT: BRP-02125
CAS: 3768-18-1
MF: C11H15N3O6
MF: 285.25
Purity: ≥95%
Appearance: White to Pale Yellow Solid
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Storage: Store at -20 °C
Density: 1.72±0.1 g/cm3 (Predicted)
Melting Point: 123-124 °C
Symbol: ac4C
InChIKey: NIDVTARKFBZMOT-PEBGCTIMSA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)
CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O
IUPAC Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C11H15N3O6/c1-5(16)12-7-2-3-14(11(19)13-7)10-9(18)8(17)6(4-15)20-10/h2-3,6,8-10,15,17-18H,4H2,1H3,(H,12,13,16,19)/t6-,8-,9-,10-/m1/s1
Synonyms: Cytidine, N-acetyl-; N-Acetylcytidine; 4-Acetyl-1-(beta-D-ribofuranosyl)cytosine; Acetylcytidine; N-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide; 4-Acetylcytidine; 4-(Acetylamino)-1-(β-D-ribofuranosyl)pyrimidin-2(1H)-one; N-(1,2-dihydro-2-oxo-1-β-D-ribofuranosyl-4-pyrimidinyl)-acetamide

Epoxyqueuosine (BRP-02126)

Description: Epoxyqueuosine is a crucial compound used in biomedical field for the development of drugs to study antibiotic-resistant bacterial infections. It plays a vital role in synthesizing modified queuosine, which enhances the efficacy of antibiotics against resistant pathogens.
CAT: BRP-02126
CAS: 107865-20-3
MF: C17H23N5O8
MF: 425.39
Purity: ≥98%
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Density: 2.33±0.1 g/cm3
Symbol: oQ
InChIKey: RRCFLRBBBFZLSB-MPMHWICOSA-N
CanonicalSMILES: C1=C(C2=C(N1C3C(C(C(O3)CO)O)O)N=C(NC2=O)N)CNC4C(C(C5C4O5)O)O
IUPAC Name: 2-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-[[(3,4-dihydroxy-6-oxabicyclo[3.1.0]hexan-2-yl)amino]methyl]-3H-pyrrolo[2,3-d]pyrimidin-4-one
InChI: InChI=1S/C17H23N5O8/c18-17-20-14-6(15(28)21-17)4(1-19-7-9(25)10(26)13-12(7)30-13)2-22(14)16-11(27)8(24)5(3-23)29-16/h2,5,7-13,16,19,23-27H,1,3H2,(H3,18,20,21,28)/t5-,7?,8-,9?,10?,11-,12?,13?,16-/m1/s1
Synonyms: 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-5-[[(3,4-dihydroxy-6-oxobicyclo[3.1.0]hex-2-yl) amino]methyl]-1,7-dihydro-7-b-D-ribofuranosyl-; 7-(5-((2,3-Epoxy-4,5-dihydroxycyclopent-1-yl)amino)methyl)-7-deazaguanosine; 6-Amino-3-(((3,4-dihydroxy-6-oxabicyclo(3.1.0)hex-2-yl)amino)methyl)-1,5-dihydro-1-beta-D-ribofuranosyl-4H-pyrrolo(2,3-d)pyrimidin-4-one

Lysidine (BRP-02127)

Description: Lysidine is a vital molecule used in the synthesis of transfer RNA (tRNA), serving as a modified base. This product excels in the management of various diseases related to tRNA metabolism disorders, such as lysine-related leukoencephalopathy. Its high purity and efficacy make it an essential tool for researchers and scientists in the biomedical field.
CAT: BRP-02127
CAS: 116120-47-9
MF: C15H25N5O6.HCl
MF: 407.85
Purity: ≥95%
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Symbol: k2C
InChIKey: BTLJFKUMSPUPNB-ZGVNSRHASA-N
CanonicalSMILES: Cl.O=C(O)C(N)CCCCN=C1N=C(N)C=CN1C2OC(CO)C(O)C2O
IUPAC Name: (2S)-2-amino-6-[[4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-ylidene]amino]hexanoic acid;hydrochloride
InChI: InChI=1S/C15H25N5O6.ClH/c16-8(14(24)25)3-1-2-5-18-15-19-10(17)4-6-20(15)13-12(23)11(22)9(7-21)26-13;/h4,6,8-9,11-13,21-23H,1-3,5,7,16H2,(H,24,25)(H2,17,18,19);1H/t8-,9+,11+,12+,13+;/m0./s1
Synonyms: L-Lysine, N6-(4-amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinylidene)-, hydrochloride (1:1); L-Lysine, N6-(4-amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinylidene)-, monohydrochloride; Lysidine (nucleoside); N6-(4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinylidene)-L-lysine hydrochloride
Related CAS: 144796-96-3 (free base)

N6-Acetyladenosine (BRP-02128)

Description: N6-Acetyladenosine, a remarkable biomedical commodity, manifests its indispensable role in the oncological landscape. Holding the prowess as a nucleoside analog, it exerts a profound hindrance upon the inexorable growth of malignant cells, effectively triggering their untimely demise through apoptosis induction. The intrinsic antitumor attributes exhibited by N6-Acetyladenosine unmask its promising potential, thereby rendering it a plausible candidate for incorporation into targeted chemotherapy protocols capable of subduing a diverse array of tumor classifications.
CAT: BRP-02128
CAS: 16265-37-5
MF: C12H15N5O5
MF: 309.28
Purity: ≥95%
Appearance: White to Off-white Powder
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Storage: Store at -20 °C
Density: 1.87±0.1 g/cm3
Symbol: ac6A
InChIKey: SLLVJTURCPWLTP-WOUKDFQISA-N
Solubility: Soluble in DMF, DMSO, Ethanol, Methanol
CanonicalSMILES: CC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O
IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]acetamide
InChI: InChI=1S/C12H15N5O5/c1-5(19)16-10-7-11(14-3-13-10)17(4-15-7)12-9(21)8(20)6(2-18)22-12/h3-4,6,8-9,12,18,20-21H,2H2,1H3,(H,13,14,16,19)/t6-,8-,9-,12-/m1/s1
Synonyms: Adenosine, N-acetyl-; N-Acetyladenosine; N6-acetyl-adenosine; N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)acetamide; N-(9-β-D-Ribofuranosyl-9-H-purin-6-yl)-acetamide

5-Methoxycarbonylmethyl-2-thiouridine (BRP-02129)

Description: 5-(Methoxycarbonylmethyl)-2-thiouridine can be used as analyte in biological study for attomole quantification and global profile of RNA modifications in study of epitranscriptome of human neural stem cells. It can also be used to biological computational studies to provide insights into effects of modified ribonucleotides and Mg2+ on structures and stabilities of tRNAs. A trace nucleoside, isolated from yeast transfer RNA. A nucleoside in the anticodon at the wobble position of some Saccharomyces cerevisiae bacteria.
CAT: BRP-02129
CAS: 20299-15-4
MF: C12H16N2O7S
MF: 332.33
Purity: ≥95%
Appearance: White to Off-white Powder
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Storage: Store at RT
Density: 1.6±0.1 g/cm3
Melting Point: 195-197 °C
Symbol: mcm5s2U
InChIKey: HLZXTFWTDIBXDF-PNHWDRBUSA-N
CanonicalSMILES: COC(=O)CC1=CN(C(=S)NC1=O)C2C(C(C(O2)CO)O)O
IUPAC Name: methyl 2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-2-sulfanylidenepyrimidin-5-yl]acetate
InChI: InChI=1S/C12H16N2O7S/c1-20-7(16)2-5-3-14(12(22)13-10(5)19)11-9(18)8(17)6(4-15)21-11/h3,6,8-9,11,15,17-18H,2,4H2,1H3,(H,13,19,22)/t6-,8-,9-,11-/m1/s1
Synonyms: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-4-oxo-1-β-D-ribofuranosyl-2-thioxo-, methyl ester; 5-(Methoxycarbonylmethyl)-2-thiouridine; 5-(2-methoxy-2-oxoethyl)-1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 5-(2-methoxy-2-oxoethyl)2-thiouridine

3-Methylcytidine (BRP-02130)

Description: 3-Methylcytidine is a modified nucleoside derived from cytidine, where a methyl group is attached to the third carbon of the cytidine molecule. This modification can occur naturally in various RNA molecules, playing a role in the regulation of gene expression and the stability of RNA. Modified nucleosides like 3-methylcytidine are often found in tRNA, rRNA, and other non-coding RNAs, contributing to the proper functioning of the cellular machinery.
CAT: BRP-02130
CAS: 2140-64-9
MF: C10H15N3O5
MF: 257.24
Purity: ≥95%
Appearance: White to Off-white Crystalline Powder
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Storage: Store at 2-8 °C, under inert atmosphere
Density: 1.71±0.1 g/cm3 (Predicted)
Melting Point: 169-170 °C
Boiling Point: 471.9±55.0 °C at 760 mmHg
Symbol: m3C
InChIKey: RDPUKVRQKWBSPK-ZOQUXTDFSA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)
CanonicalSMILES: CN1C(=N)C=CN(C1=O)C2C(C(C(O2)CO)O)O
IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-imino-3-methylpyrimidin-2-one
InChI: InChI=1S/C10H15N3O5/c1-12-6(11)2-3-13(10(12)17)9-8(16)7(15)5(4-14)18-9/h2-3,5,7-9,11,14-16H,4H2,1H3/t5-,7-,8-,9-/m1/s1
Synonyms: N3-Methylcytidine; Cytidine, 3-methyl-; 3-methyl-4,N(4)-didehydro-3,4-dihydrocytidine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-imino-3-methyl-3,4-dihydropyrimidin-2(1H)-one; 3-Methyl-3,4-dihydrocytidine

N6-Glycinylcarbamoyladenosine (BRP-02132)

Description: N6-glycinylcarbamoyladenosine is a remarkable and highly potent inhibitor meticulously employed in studying selective cancers.
CAT: BRP-02132
CAS: 29902-55-4
MF: C13H16N6O7
MF: 368.31
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Density: 2.03±0.1 g/cm3
Symbol: g6A
InChIKey: AHESNRWOMYGILC-JJNLEZRASA-N
CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)NC(=O)NCC(=O)O
IUPAC Name: 2-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]carbamoylamino]acetic acid
InChI: InChI=1S/C13H16N6O7/c20-2-5-8(23)9(24)12(26-5)19-4-17-7-10(15-3-16-11(7)19)18-13(25)14-1-6(21)22/h3-5,8-9,12,20,23-24H,1-2H2,(H,21,22)(H2,14,15,16,18,25)/t5-,8-,9-,12-/m1/s1
Synonyms: Glycine, N-[[(9-b-D-ribofuranosyl-9H-purin-6-yl)amino]carbonyl]-; ((9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)carbamoyl)glycine; Glycine, N-[(9-β-D-ribofuranosyl-9H-purin-6-yl)carbamoyl]-; N-[[(9-β-D-Ribofuranosyl-9H-purin-6-yl)amino]carbonyl]glycine; N-[9-(β-D-Ribofuranosyl)-purin-6-ylcarbamoyl]glycine; N-[9-(β-D-Ribofuranosyl-9H-purin-6-yl)carbamoyl]glycine

3-(3-Amino-3-carboxypropyl)uridine (BRP-02133)

Description: 3-(3-Amino-3-carboxypropyl)uridine, an indispensable compound extensively applied in biomedical research and pharmaceutical advancement, assumes a pivotal function in the amalgamation of nucleic acids and RNA alteration. Its multifaceted attributes make it an invaluable tool for unraveling the intricate intricacies of RNA's structure, function, and the impact of selective modifications on a diverse array of ailments, encompassing cancer and neurodegenerative disorders.
CAT: BRP-02133
CAS: 52745-94-5
MF: C13H19N3O8
MF: 345.31
Purity: 97%
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Density: 1.643±0.06 g/cm3
Boiling Point: 667.9±65.0 °C at 760 mmHg
Symbol: acp3U
InChIKey: YXNIEZJFCGTDKV-JANFQQFMSA-N
CanonicalSMILES: C1=CN(C(=O)N(C1=O)CCC(C(=O)O)N)C2C(C(C(O2)CO)O)O
IUPAC Name: 2-amino-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxopyrimidin-1-yl]butanoic acid
InChI: InChI=1S/C13H19N3O8/c14-6(12(21)22)1-3-15-8(18)2-4-16(13(15)23)11-10(20)9(19)7(5-17)24-11/h2,4,6-7,9-11,17,19-20H,1,3,5,14H2,(H,21,22)/t6?,7-,9-,10-,11-/m1/s1
Synonyms: 1(2H)-Pyrimidinebutanoic acid, a-amino-3,6-dihydro-2,6-dioxo-3-b-D-ribofuranosyl-; α-Amino-3,6-dihydro-2,6-dioxo-3-β-D-ribofuranosyl-1(2H)-pyrimidinebutanoic acid; 2-amino-4-(3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)butanoic acid

3-(3-Amino-3-carboxypropyl)-1-methylpseudoUridine (BRP-02134)

Description: The hypermodified residue 1-methyl-3-(3-amino-3-carboxypropyl) pseudoUridine (m1acp3Ψ) was first isolated from the RNA of cells of an established line of cells of Chinese hamster in 1974 and was localized in 18S rRNAs.
CAT: BRP-02134
CAS: 52777-29-4
MF: C14H21N3O8
MF: 359.34
Purity: ≥99%
Appearance: White crystalline powder
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Storage: Store at 2-8 °C
Density: 1.575±0.06 g/cm3
Boiling Point: 665.2±65.0 °C at 760 mmHg
Symbol: m1acp3Y
InChIKey: CTPQMQZKRWLMRA-LYTXVXJPSA-N
CanonicalSMILES: CN1C=C(C(=O)N(C1=O)CCC(C(=O)O)N)C2C(C(C(O2)CO)O)O
IUPAC Name: 2-amino-4-[5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-methyl-2,6-dioxopyrimidin-1-yl]butanoic acid
InChI: InChI=1S/C14H21N3O8/c1-16-4-6(11-10(20)9(19)8(5-18)25-11)12(21)17(14(16)24)3-2-7(15)13(22)23/h4,7-11,18-20H,2-3,5,15H2,1H3,(H,22,23)/t7?,8-,9-,10-,11+/m1/s1
Synonyms: 1(2H)-Pyrimidinebutanoic acid, a-amino-3,6-dihydro-3-methyl-2,6-dioxo-5-b-D-ribofuranosyl-; Acpmpsu; 1-Methyl-3-(3-carboxy-3-aminopropyl)-5-(beta-D-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione; α-Amino-3,6-dihydro-3-methyl-2,6-dioxo-5-β-D-ribofuranosyl-1(2H)-pyrimidinebutanoic acid; 1-Methyl-3-(3-amino-3-carboxypropyl)pseudouridine; 1-Methyl-3-γ-(α-amino-α-carboxypropyl)pseudouridine

Wybutosine (BRP-02135)

Description: Wybutosine is a highly modified nucleoside found in phenylalanine tRNA that plays a crucial role in ensuring the accuracy of protein synthesis. Its unique structure and function underscore its importance in the translation process and highlight its relevance in both basic biological research and potential clinical applications.
CAT: BRP-02135
CAS: 55196-46-8
MF: C21H28N6O9
MF: 508.49
Purity: ≥98%
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Density: 1.68±0.1 g/cm3
Symbol: yW
InChIKey: QAOHCFGKCWTBGC-QHOAOGIMSA-N
CanonicalSMILES: CC1=C(N2C(=O)C3=C(N(C2=N1)C)N(C=N3)C4C(C(C(O4)CO)O)O)CCC(C(=O)OC)NC(=O)OC
IUPAC Name: methyl (2S)-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4,6-dimethyl-9-oxoimidazo[1,2-a]purin-7-yl]-2-(methoxycarbonylamino)butanoate
InChI: InChI=1S/C21H28N6O9/c1-9-11(6-5-10(19(32)34-3)24-21(33)35-4)27-17(31)13-16(25(2)20(27)23-9)26(8-22-13)18-15(30)14(29)12(7-28)36-18/h8,10,12,14-15,18,28-30H,5-7H2,1-4H3,(H,24,33)/t10-,12+,14+,15+,18+/m0/s1
Synonyms: 3H-Imidazo[1,2-a]purine-7-butanoic acid, 4,9-dihydro-α-[(methoxycarbonyl)amino]-4,6-dimethyl-9-oxo-3-β-D-ribofuranosyl-, methyl ester, (S)-; Nucleoside Y; Nucleoside Y, from Saccharomycescerevisiae; Y-Nucleoside; 3H-Imidazo[1,2-a]purine-7-butanoic acid, 4,9-dihydro-α-[(methoxycarbonyl)amino]-4,6-dimethyl-9-oxo-3-β-D-ribofuranosyl-, methyl ester, (αS)-

Hydroxywybutosine (BRP-02137)

Description: Hydroxywybutosine is a crucial compound in the biomedical industry for treating viral infections, particularly those caused by the Herpes Simplex Virus (HSV). This antiviral drug inhibits the replication of HSV by targeting essential enzymes within infected cells. With its potent antiviral activity, Hydroxywybutosine proves to be a promising therapeutic option for managing viral infections, offering potential relief and improved patient outcomes.
CAT: BRP-02137
CAS: 945684-11-7
MF: C21H28N6O10
MF: 524.49
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Density: 1.75±0.1 g/cm3
Symbol: OHyW
InChIKey: OBCAXUIWCCSJPT-JPZHCBQBSA-N
CanonicalSMILES: CC1=C(N2C(=O)C3=C(N(C2=N1)C)N(C=N3)C4C(C(C(O4)CO)O)O)CC(C(C(=O)OC)NC(=O)OC)O
IUPAC Name: methyl (2S)-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4,6-dimethyl-9-oxoimidazo[1,2-a]purin-7-yl]-3-hydroxy-2-(methoxycarbonylamino)butanoate
InChI: InChI=1S/C21H28N6O10/c1-8-9(5-10(29)12(19(33)35-3)24-21(34)36-4)27-17(32)13-16(25(2)20(27)23-8)22-7-26(13)18-15(31)14(30)11(6-28)37-18/h7,10-12,14-15,18,28-31H,5-6H2,1-4H3,(H,24,34)/t10?,11-,12?,14-,15-,18-/m1/s1
Synonyms: 3H-Imidazo[1,2-a]purine-7-butanoic acid, 4,9-dihydro-β-hydroxy-α-[(methoxycarbonyl)amino]-4,6-dimethyl-9-oxo-3-β-D-ribofuranosyl-, methyl ester, (αS)-; Methyl (αS)-4,9-dihydro-β-hydroxy-α-[(methoxycarbonyl)amino]-4,6-dimethyl-9-oxo-3-β-D-ribofuranosyl-3H-imidazo[1,2-a]purine-7-butanoate; Methyl (2S)-4-(3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4,6-dimethyl-9-oxo-4,9-dihydro-3H-imidazo[1,2-a]purin-7-yl)-3-hydroxy-2-((methoxycarbonyl)amino)butanoate
Related CAS: 84270-21-3 (Methyl 4,9-dihydro-β-hydroxy-α-[(methoxycarbonyl)amino]-4,6-dimethyl-9-oxo-1-β-D-ribofuranosyl-1H-imidazo[1,2-a]purine-7-butanoate)

N2,7,2'-O-Trimethylguanosine (BRP-02138)

Description: N2,7,2'-O-Trimethylguanosine, a paramount compound, finds its indispensability in the field of biomedicine. Its significance lies in its pivotal participation in the scientific exploration and enhancement of antiviral agents that focus on the alteration of viral RNA. The inhibitory effects displayed by N2,7,2'-O-trimethylguanosine against select viruses have been highly encouraging, thereby establishing its potential as a prospective remedy for various viral ailments such as the respiratory syncytial virus and influenza infections.
CAT: BRP-02138
CAS: 872710-82-2
MF: C13H19N5O5
MF: 325.32
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Symbol: m2,7Gm
InChIKey: IGUVTVZUVROGNX-WOUKDFQISA-N
CanonicalSMILES: O=C1N=C([N-]C)NC2=C1[N+](=CN2C3OC(CO)C(O)C3OC)C
IUPAC Name: 9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-7-methyl-2-(methylamino)-9H-purin-7-ium-6-olate
InChI: InChI=1S/C13H19N5O5/c1-14-13-15-10-7(11(21)16-13)17(2)5-18(10)12-9(22-3)8(20)6(4-19)23-12/h5-6,8-9,12,19-20H,4H2,1-3H3,(H-,14,15,16,21)/t6-,8-,9-,12-/m1/s1
Synonyms: Guanosine, N,7-dimethyl-2'-O-methyl-, inner salt; N,7-Dimethyl-2'-O-methylguanosine, inner salt

(S)-5-(Carboxyhydroxymethyl)uridine methyl ester (BRP-02139)

Description: (S)-5-(Carboxyhydroxymethyl)uridine methyl ester is a remarkable pharmaceutical compound widely employed in the biomedical sector, demonstrating exceptional efficacy in alleviating diverse ailments. Renowned for its antiviral properties, particularly in combatting RNA viruses, this compound showcases potential in mitigating viral infections.
CAT: BRP-02139
CAS: 89665-83-8
MF: C12H16N2O9
MF: 332.27
Purity: ≥95%
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Density: 1.687±0.06 g/cm3
Symbol: mchm5U
InChIKey: JNVLKTZUCGRYNN-MGPZHUSASA-N
CanonicalSMILES: COC(=O)C(C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O)O
IUPAC Name: methyl (2S)-2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]-2-hydroxyacetate
InChI: InChI=1S/C12H16N2O9/c1-22-11(20)6(16)4-2-14(12(21)13-9(4)19)10-8(18)7(17)5(3-15)23-10/h2,5-8,10,15-18H,3H2,1H3,(H,13,19,21)/t5-,6+,7-,8-,10-/m1/s1
Synonyms: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester, (αS)-; Methyl (S)-2-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-hydroxyacetate; 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester, (S)-; Methyl (αS)-1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate; 5-[(1S)-1-Hydroxy-2-methoxy-2-oxoethyl]uridine; (S)-mchm5U
Related CAS: 1632399-25-7 (Deleted CAS)

(S)-5-(Carboxyhydroxymethyl)uridine (BRP-02140)

Description: (S)-5-(Carboxyhydroxymethyl)uridine, a highly bioactive compound widely utilized in the biomedical industry, has garnered considerable attention due to its remarkable potential in therapeutic applications against a range of diseases, including cancer, viral infections, and neurodegenerative disorders. Extensive research has revealed its impressive anti-tumor and anti-viral properties, rendering it an invaluable asset for the advancement of drug discovery and biomedical research. Its multifaceted capabilities highlight the significant role it plays in the pursuit of improved healthcare and scientific exploration.
CAT: BRP-02140
CAS: 89708-80-5
MF: C11H14N2O9
MF: 318.24
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Density: 1.855±0.06 g/cm3
Symbol: chm5U
InChIKey: UVGCZRPOXXYZKH-XLKNOJSPSA-N
CanonicalSMILES: O=C(O)C(O)C1=CN(C(=O)NC1=O)C2OC(CO)C(O)C2O
IUPAC Name: (S)-2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]-2-hydroxyacetic acid
InChI: InChI=1S/C11H14N2O9/c14-2-4-6(16)7(17)9(22-4)13-1-3(5(15)10(19)20)8(18)12-11(13)21/h1,4-7,9,14-17H,2H2,(H,19,20)(H,12,18,21)/t4-,5+,6-,7-,9-/m1/s1
Synonyms: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-a-hydroxy-2,4-dioxo-1-b-D-ribofuranosyl-, (S)-; 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-, (αS)-; (αS)-1,2,3,4-Tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetic acid; (S)-2-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-hydroxyacetic acid
Related CAS: 934743-11-0 (5-(Carboxyhydroxymethyl)uridine) ; 127911-55-1 ((R)-5-(Carboxyhydroxymethyl)uridine)

2'-O-Methyl-N1-methyladenosine (BRP-02141)

Description: N1,O2'-Dimethyladenosine is a naturally occurring modified ribonucleotide found in tRNA.
CAT: BRP-02141
CAS: 91101-00-7
MF: C12H17N5O4
MF: 295.29
Purity: ≥95%
Appearance: White to Off-White Solid
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Storage: Store at 2-8 °C, under inert atmosphere
Density: 1.69±0.1 g/cm3 (Predicted)
Melting Point: >115 °C (dec.)
Boiling Point: 612.0±65.0 °C at 760 mmHg
Symbol: m1Am
InChIKey: ABZGKVIDNBLRBI-WOUKDFQISA-N
Solubility: Soluble in Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
CanonicalSMILES: CN1CNC2=C(C1=N)N=CN2C3C(C(C(O3)CO)O)OC
IUPAC Name: (2R,3R,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-2,3-dihydropurin-9-yl)-4-methoxyoxolan-3-ol
InChI: InChI=1S/C12H19N5O4/c1-16-4-15-11-7(10(16)13)14-5-17(11)12-9(20-2)8(19)6(3-18)21-12/h5-6,8-9,12-13,15,18-19H,3-4H2,1-2H3/t6-,8-,9-,12-/m1/s1
Synonyms: N1,O2'-Dimethyladenosine; 1-Methyl-2'-O-methyladenosine; 2'-O-Methyl-1-methyladenosine; 1,2'-O-dimethyladenosine
Related CAS: 59867-24-2 (HI salt)

2'-O-Methyluridine 5-oxyacetic acid methyl ester (BRP-02142)

Description: 2'-O-Methyluridine 5-oxyacetic acid methyl ester is a modified nucleoside with enhanced stability and binding properties, making it valuable in RNA therapeutics, biochemical research, and synthetic biology. Its modifications can significantly impact the chemical and biological behavior of RNA, contributing to advances in understanding RNA function and developing novel RNA-based treatments.
CAT: BRP-02142
CAS: 1967829-21-5
MF: C13H18N2O9
MF: 346.29
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Density: 1.53±0.1 g/cm3
Symbol: mcmo5Um
InChIKey: KMWJTPJUZPBLCW-UGKPPGOTSA-N
CanonicalSMILES: COC1C(C(OC1N2C=C(C(=O)NC2=O)OCC(=O)OC)CO)O
IUPAC Name: methyl 2-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]oxyacetate
InChI: InChI=1S/C13H18N2O9/c1-21-8(17)5-23-6-3-15(13(20)14-11(6)19)12-10(22-2)9(18)7(4-16)24-12/h3,7,9-10,12,16,18H,4-5H2,1-2H3,(H,14,19,20)/t7-,9-,10-,12-/m1/s1
Synonyms: Acetic acid, 2-[[1,2,3,4-tetrahydro-1-(2-O-methyl-β-D-ribofuranosyl)-2,4-dioxo-5-pyrimidinyl]oxy]-, methyl ester; mcmo5Um; 5-Methoxycarbonylmethoxy-2'-O-methyluridine; methyl 2-((1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)oxy)acetate

3-(3-Amino-3-carboxypropyl)-5,6-dihydrouridine (BRP-02143)

Description: 3-(3-Amino-3-carboxypropyl)-5,6-dihydrouridine is a modified nucleoside that combines the structural features of dihydrouridine and an amino-carboxypropyl side chain. This modification introduces flexibility and additional functional groups into the RNA, impacting its stability and interactions. It is valuable in RNA structure studies, synthetic biology, and the development of RNA-based therapeutics.
CAT: BRP-02143
CAS: 1353039-95-8
MF: C13H21N3O8
MF: 347.32
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Density: 1.602±0.06 g/cm3
Boiling Point: 660.4±65.0 °C at 760 mmHg
Symbol: acp3D
InChIKey: VBRZFUQRBSFADN-JANFQQFMSA-N
CanonicalSMILES: C1CN(C(=O)N(C1=O)CCC(C(=O)O)N)C2C(C(C(O2)CO)O)O
IUPAC Name: 2-amino-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxo-1,3-diazinan-1-yl]butanoic acid
InChI: InChI=1S/C13H21N3O8/c14-6(12(21)22)1-3-15-8(18)2-4-16(13(15)23)11-10(20)9(19)7(5-17)24-11/h6-7,9-11,17,19-20H,1-5,14H2,(H,21,22)/t6?,7-,9-,10-,11-/m1/s1
Synonyms: 1(2H)-Pyrimidinebutanoic acid, α-aminotetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-; α-Aminotetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-1(2H)-pyrimidinebutanoic acid; 2-amino-4-(3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,6-dioxotetrahydropyrimidin-1(2H)-yl)butanoic acid
* Only for research. Not suitable for any diagnostic or therapeutic use.
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