Nucleosides - RNA / BOC Sciences

D-Glucose-[2-13C,2-d1] (BRP-02121)

Description: Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a crucial role in photosynthesis and energy source required for cellular respiration. D-Glucose is used in various metabolic processes including the enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in type 2 diabetes mellitus detection and potentially Huntington's disease through blood-glucose analysis in type 1 diabetes mellitus.

CAT: BRP-02121

CAS: 83379-46-8

MF: C5[13C]H11DO6

MF: 182.15

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InChIKey: GZCGUPFRVQAUEE-BLIQJOKYSA-N

CanonicalSMILES: C(C(C(C(C(C=O)O)O)O)O)O

IUPAC Name: (2R,3S,4R,5R)-2-deuterio-2,3,4,5,6-pentahydroxy(2-13C)hexanal

InChI: InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1/i3+1D

Synonyms: D-[2-13C,2-2H]glucose; D-Glucose-2-13C-2-C-2H; D-Glucose-2-13C-2-C-d; D-Glucose-13C,d1; (+)-Glucose-2-13C,2-d1; Glucose-2-13C,2-d1; D-(+)-Glucose-2-13C,2-d1; D-Glucose-2-13C,2-d1

Related CAS: 50-99-7 (unlabelled)

N4-Acetyl-2'-O-methylcytidine (BRP-02123)

Description: N4-Acetyl-2'-O-methylcytidine is an innovative and scientifically advanced compound, emerging as a groundbreaking solution for studying RNA virus-induced viral afflictions. By specifically pinpointing viral enzymes or obstructing viral replication, it manifests remarkable antiviral attributes.

CAT: BRP-02123

CAS: 113886-71-8

MF: C12H17N3O6

MF: 299.28

Purity: ≥97% by HPLC

Appearance: White to Yellow Solid

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Storage: Store at -20 °C, under inert atmosphere

Density: 1.58±0.1 g/cm3 (Predicted)

Symbol: ac⁴Cm

InChIKey: CYDFBLGNJUNSCC-QCNRFFRDSA-N

Solubility: Soluble in Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)OC

IUPAC Name: N-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C12H17N3O6/c1-6(17)13-8-3-4-15(12(19)14-8)11-10(20-2)9(18)7(5-16)21-11/h3-4,7,9-11,16,18H,5H2,1-2H3,(H,13,14,17,19)/t7-,9-,10-,11-/m1/s1

Synonyms: Cytidine, N-acetyl-2'-O-methyl-; N4-Ac-2'-OMe-rC; N4-Acetyl-2'-O-methyl cytidine; N-Acetyl-2'-O-methylcytidine; N-(1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

N6-Threonylcarbamoyladenosine (BRP-02124)

Description: N6-Threonylcarbamoyladenosine is an indispensable bioactive compound in the biomedical sector, aiding in studying an array of malignancies, predominantly those afflicting the mammary and pulmonary tissues.

CAT: BRP-02124

CAS: 24719-82-2

MF: C15H20N6O8

MF: 412.36

Purity: ≥98% by HPLC

Appearance: White to beige soild

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Storage: Store at -20 °C, under inert atmosphere

Density: 1.96±0.1 g/cm3

Symbol: t⁶A

InChIKey: UNUYMBPXEFMLNW-DWVDDHQFSA-N

Solubility: Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly, Heated)

CanonicalSMILES: CC(C(C(=O)O)NC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O)O

IUPAC Name: (2S,3R)-2-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]carbamoylamino]-3-hydroxybutanoic acid

InChI: InChI=1S/C15H20N6O8/c1-5(23)7(14(26)27)19-15(28)20-11-8-12(17-3-16-11)21(4-18-8)13-10(25)9(24)6(2-22)29-13/h3-7,9-10,13,22-25H,2H2,1H3,(H,26,27)(H2,16,17,19,20,28)/t5-,6-,7+,9-,10-,13-/m1/s1

Synonyms: L-Threonine, N-[[(9-b-D-ribofuranosyl-9H-purin-6-yl) amino]carbonyl]-; N-{[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl}adenosine; N-[(9-beta-D-ribofuranosylpurin-6-yl)carbamoyl]-L-threonine; N-[[(9-β-D-Ribofuranosyl-9H-purin-6-yl)amino]carbonyl]-L-threonine; N-(6-Nebularinylcarbamoyl)threonine; N-(6-Purinylcarbamoyl)-L-threonine riboside; N-[(9-β-D-Ribofuranosyl-9H-purin-6-yl)carbamoyl]-L-threonine; N-[N-(9-β-D-Ribofuranosylpurin-6-yl)carbamoyl]threonine; N6-(N-Threonylcarbonyl)adenosine; N6-Carbamoylthreonyl adenosine; t6-Adenosine

N4-Acetylcytidine (BRP-02125)

Description: N4-Acetylcytidine is an extraordinary bioactive compound, widely used in the research of viral afflictions. It can unyieldingly thwart viral replication and diminish the onerous viral burden.

CAT: BRP-02125

CAS: 3768-18-1

MF: C11H15N3O6

MF: 285.25

Purity: ≥95%

Appearance: White to Pale Yellow Solid

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Storage: Store at -20 °C

Density: 1.72±0.1 g/cm3 (Predicted)

Melting Point: 123-124 °C

Symbol: ac⁴C

InChIKey: NIDVTARKFBZMOT-PEBGCTIMSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O

IUPAC Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C11H15N3O6/c1-5(16)12-7-2-3-14(11(19)13-7)10-9(18)8(17)6(4-15)20-10/h2-3,6,8-10,15,17-18H,4H2,1H3,(H,12,13,16,19)/t6-,8-,9-,10-/m1/s1

Synonyms: Cytidine, N-acetyl-; N-Acetylcytidine; 4-Acetyl-1-(beta-D-ribofuranosyl)cytosine; Acetylcytidine; N-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide; 4-Acetylcytidine; 4-(Acetylamino)-1-(β-D-ribofuranosyl)pyrimidin-2(1H)-one; N-(1,2-dihydro-2-oxo-1-β-D-ribofuranosyl-4-pyrimidinyl)-acetamide

Epoxyqueuosine (BRP-02126)

Description: Epoxyqueuosine is a crucial compound used in biomedical field for the development of drugs to study antibiotic-resistant bacterial infections. It plays a vital role in synthesizing modified queuosine, which enhances the efficacy of antibiotics against resistant pathogens.

CAT: BRP-02126

CAS: 107865-20-3

MF: C17H23N5O8

MF: 425.39

Purity: ≥98%

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Density: 2.33±0.1 g/cm3

Symbol: oQ

InChIKey: RRCFLRBBBFZLSB-MPMHWICOSA-N

CanonicalSMILES: C1=C(C2=C(N1C3C(C(C(O3)CO)O)O)N=C(NC2=O)N)CNC4C(C(C5C4O5)O)O

IUPAC Name: 2-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-[[(3,4-dihydroxy-6-oxabicyclo[3.1.0]hexan-2-yl)amino]methyl]-3H-pyrrolo[2,3-d]pyrimidin-4-one

InChI: InChI=1S/C17H23N5O8/c18-17-20-14-6(15(28)21-17)4(1-19-7-9(25)10(26)13-12(7)30-13)2-22(14)16-11(27)8(24)5(3-23)29-16/h2,5,7-13,16,19,23-27H,1,3H2,(H3,18,20,21,28)/t5-,7?,8-,9?,10?,11-,12?,13?,16-/m1/s1

Synonyms: 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-5-[[(3,4-dihydroxy-6-oxobicyclo[3.1.0]hex-2-yl) amino]methyl]-1,7-dihydro-7-b-D-ribofuranosyl-; 7-(5-((2,3-Epoxy-4,5-dihydroxycyclopent-1-yl)amino)methyl)-7-deazaguanosine; 6-Amino-3-(((3,4-dihydroxy-6-oxabicyclo(3.1.0)hex-2-yl)amino)methyl)-1,5-dihydro-1-beta-D-ribofuranosyl-4H-pyrrolo(2,3-d)pyrimidin-4-one

Lysidine (BRP-02127)

Description: Lysidine is a vital molecule used in the synthesis of transfer RNA (tRNA), serving as a modified base. This product excels in the management of various diseases related to tRNA metabolism disorders, such as lysine-related leukoencephalopathy. Its high purity and efficacy make it an essential tool for researchers and scientists in the biomedical field.

CAT: BRP-02127

CAS: 116120-47-9

MF: C15H25N5O6.HCl

MF: 407.85

Purity: ≥95%

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Symbol: k²C

InChIKey: BTLJFKUMSPUPNB-ZGVNSRHASA-N

CanonicalSMILES: Cl.O=C(O)C(N)CCCCN=C1N=C(N)C=CN1C2OC(CO)C(O)C2O

IUPAC Name: (2S)-2-amino-6-[[4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-ylidene]amino]hexanoic acid;hydrochloride

InChI: InChI=1S/C15H25N5O6.ClH/c16-8(14(24)25)3-1-2-5-18-15-19-10(17)4-6-20(15)13-12(23)11(22)9(7-21)26-13;/h4,6,8-9,11-13,21-23H,1-3,5,7,16H2,(H,24,25)(H2,17,18,19);1H/t8-,9+,11+,12+,13+;/m0./s1

Synonyms: L-Lysine, N6-(4-amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinylidene)-, hydrochloride (1:1); L-Lysine, N6-(4-amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinylidene)-, monohydrochloride; Lysidine (nucleoside); N6-(4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinylidene)-L-lysine hydrochloride

Related CAS: 144796-96-3 (free base)

N6-Acetyladenosine (BRP-02128)

Description: N6-Acetyladenosine, a remarkable biomedical commodity, manifests its indispensable role in the oncological landscape. Holding the prowess as a nucleoside analog, it exerts a profound hindrance upon the inexorable growth of malignant cells, effectively triggering their untimely demise through apoptosis induction. The intrinsic antitumor attributes exhibited by N6-Acetyladenosine unmask its promising potential, thereby rendering it a plausible candidate for incorporation into targeted chemotherapy protocols capable of subduing a diverse array of tumor classifications.

CAT: BRP-02128

CAS: 16265-37-5

MF: C12H15N5O5

MF: 309.28

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at -20 °C

Density: 1.87±0.1 g/cm3

Symbol: ac⁶A

InChIKey: SLLVJTURCPWLTP-WOUKDFQISA-N

Solubility: Soluble in DMF, DMSO, Ethanol, Methanol

CanonicalSMILES: CC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]acetamide

InChI: InChI=1S/C12H15N5O5/c1-5(19)16-10-7-11(14-3-13-10)17(4-15-7)12-9(21)8(20)6(2-18)22-12/h3-4,6,8-9,12,18,20-21H,2H2,1H3,(H,13,14,16,19)/t6-,8-,9-,12-/m1/s1

Synonyms: Adenosine, N-acetyl-; N-Acetyladenosine; N6-acetyl-adenosine; N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)acetamide; N-(9-β-D-Ribofuranosyl-9-H-purin-6-yl)-acetamide

5-Methoxycarbonylmethyl-2-thiouridine (BRP-02129)

Description: 5-(Methoxycarbonylmethyl)-2-thiouridine can be used as analyte in biological study for attomole quantification and global profile of RNA modifications in study of epitranscriptome of human neural stem cells. It can also be used to biological computational studies to provide insights into effects of modified ribonucleotides and Mg2+ on structures and stabilities of tRNAs. A trace nucleoside, isolated from yeast transfer RNA. A nucleoside in the anticodon at the wobble position of some Saccharomyces cerevisiae bacteria.

CAT: BRP-02129

CAS: 20299-15-4

MF: C12H16N2O7S

MF: 332.33

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at RT

Density: 1.6±0.1 g/cm3

Melting Point: 195-197 °C

Symbol: mcm⁵s²U

InChIKey: HLZXTFWTDIBXDF-PNHWDRBUSA-N

CanonicalSMILES: COC(=O)CC1=CN(C(=S)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: methyl 2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-2-sulfanylidenepyrimidin-5-yl]acetate

InChI: InChI=1S/C12H16N2O7S/c1-20-7(16)2-5-3-14(12(22)13-10(5)19)11-9(18)8(17)6(4-15)21-11/h3,6,8-9,11,15,17-18H,2,4H2,1H3,(H,13,19,22)/t6-,8-,9-,11-/m1/s1

Synonyms: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-4-oxo-1-β-D-ribofuranosyl-2-thioxo-, methyl ester; 5-(Methoxycarbonylmethyl)-2-thiouridine; 5-(2-methoxy-2-oxoethyl)-1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 5-(2-methoxy-2-oxoethyl)2-thiouridine

3-Methylcytidine (BRP-02130)

Description: 3-Methylcytidine is a modified nucleoside derived from cytidine, where a methyl group is attached to the third carbon of the cytidine molecule. This modification can occur naturally in various RNA molecules, playing a role in the regulation of gene expression and the stability of RNA. Modified nucleosides like 3-methylcytidine are often found in tRNA, rRNA, and other non-coding RNAs, contributing to the proper functioning of the cellular machinery.

CAT: BRP-02130

CAS: 2140-64-9

MF: C10H15N3O5

MF: 257.24

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

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Storage: Store at 2-8 °C, under inert atmosphere

Density: 1.71±0.1 g/cm3 (Predicted)

Melting Point: 169-170 °C

Boiling Point: 471.9±55.0 °C at 760 mmHg

Symbol: m³C

InChIKey: RDPUKVRQKWBSPK-ZOQUXTDFSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: CN1C(=N)C=CN(C1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-imino-3-methylpyrimidin-2-one

InChI: InChI=1S/C10H15N3O5/c1-12-6(11)2-3-13(10(12)17)9-8(16)7(15)5(4-14)18-9/h2-3,5,7-9,11,14-16H,4H2,1H3/t5-,7-,8-,9-/m1/s1

Synonyms: N3-Methylcytidine; Cytidine, 3-methyl-; 3-methyl-4,N(4)-didehydro-3,4-dihydrocytidine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-imino-3-methyl-3,4-dihydropyrimidin-2(1H)-one; 3-Methyl-3,4-dihydrocytidine

N6-Glycinylcarbamoyladenosine (BRP-02132)

Description: N6-glycinylcarbamoyladenosine is a remarkable and highly potent inhibitor meticulously employed in studying selective cancers.

CAT: BRP-02132

CAS: 29902-55-4

MF: C13H16N6O7

MF: 368.31

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Density: 2.03±0.1 g/cm3

Symbol: g⁶A

InChIKey: AHESNRWOMYGILC-JJNLEZRASA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)NC(=O)NCC(=O)O

IUPAC Name: 2-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]carbamoylamino]acetic acid

InChI: InChI=1S/C13H16N6O7/c20-2-5-8(23)9(24)12(26-5)19-4-17-7-10(15-3-16-11(7)19)18-13(25)14-1-6(21)22/h3-5,8-9,12,20,23-24H,1-2H2,(H,21,22)(H2,14,15,16,18,25)/t5-,8-,9-,12-/m1/s1

Synonyms: Glycine, N-[[(9-b-D-ribofuranosyl-9H-purin-6-yl)amino]carbonyl]-; ((9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)carbamoyl)glycine; Glycine, N-[(9-β-D-ribofuranosyl-9H-purin-6-yl)carbamoyl]-; N-[[(9-β-D-Ribofuranosyl-9H-purin-6-yl)amino]carbonyl]glycine; N-[9-(β-D-Ribofuranosyl)-purin-6-ylcarbamoyl]glycine; N-[9-(β-D-Ribofuranosyl-9H-purin-6-yl)carbamoyl]glycine

3-(3-Amino-3-carboxypropyl)uridine (BRP-02133)

Description: 3-(3-Amino-3-carboxypropyl)uridine, an indispensable compound extensively applied in biomedical research and pharmaceutical advancement, assumes a pivotal function in the amalgamation of nucleic acids and RNA alteration. Its multifaceted attributes make it an invaluable tool for unraveling the intricate intricacies of RNA's structure, function, and the impact of selective modifications on a diverse array of ailments, encompassing cancer and neurodegenerative disorders.

CAT: BRP-02133

CAS: 52745-94-5

MF: C13H19N3O8

MF: 345.31

Purity: 97%

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Density: 1.643±0.06 g/cm3

Boiling Point: 667.9±65.0 °C at 760 mmHg

Symbol: acp³U

InChIKey: YXNIEZJFCGTDKV-JANFQQFMSA-N

CanonicalSMILES: C1=CN(C(=O)N(C1=O)CCC(C(=O)O)N)C2C(C(C(O2)CO)O)O

IUPAC Name: 2-amino-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxopyrimidin-1-yl]butanoic acid

InChI: InChI=1S/C13H19N3O8/c14-6(12(21)22)1-3-15-8(18)2-4-16(13(15)23)11-10(20)9(19)7(5-17)24-11/h2,4,6-7,9-11,17,19-20H,1,3,5,14H2,(H,21,22)/t6?,7-,9-,10-,11-/m1/s1

Synonyms: 1(2H)-Pyrimidinebutanoic acid, a-amino-3,6-dihydro-2,6-dioxo-3-b-D-ribofuranosyl-; α-Amino-3,6-dihydro-2,6-dioxo-3-β-D-ribofuranosyl-1(2H)-pyrimidinebutanoic acid; 2-amino-4-(3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)butanoic acid

3-(3-Amino-3-carboxypropyl)-1-methylpseudoUridine (BRP-02134)

Description: The hypermodified residue 1-methyl-3-(3-amino-3-carboxypropyl) pseudoUridine (m₁acp₃Ψ) was first isolated from the RNA of cells of an established line of cells of Chinese hamster in 1974 and was localized in 18S rRNAs.

CAT: BRP-02134

CAS: 52777-29-4

MF: C14H21N3O8

MF: 359.34

Purity: ≥99%

Appearance: White crystalline powder

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Storage: Store at 2-8 °C

Density: 1.575±0.06 g/cm3

Boiling Point: 665.2±65.0 °C at 760 mmHg

Symbol: m¹acp³Y

InChIKey: CTPQMQZKRWLMRA-LYTXVXJPSA-N

CanonicalSMILES: CN1C=C(C(=O)N(C1=O)CCC(C(=O)O)N)C2C(C(C(O2)CO)O)O

IUPAC Name: 2-amino-4-[5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-methyl-2,6-dioxopyrimidin-1-yl]butanoic acid

InChI: InChI=1S/C14H21N3O8/c1-16-4-6(11-10(20)9(19)8(5-18)25-11)12(21)17(14(16)24)3-2-7(15)13(22)23/h4,7-11,18-20H,2-3,5,15H2,1H3,(H,22,23)/t7?,8-,9-,10-,11+/m1/s1

Synonyms: 1(2H)-Pyrimidinebutanoic acid, a-amino-3,6-dihydro-3-methyl-2,6-dioxo-5-b-D-ribofuranosyl-; Acpmpsu; 1-Methyl-3-(3-carboxy-3-aminopropyl)-5-(beta-D-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione; α-Amino-3,6-dihydro-3-methyl-2,6-dioxo-5-β-D-ribofuranosyl-1(2H)-pyrimidinebutanoic acid; 1-Methyl-3-(3-amino-3-carboxypropyl)pseudouridine; 1-Methyl-3-γ-(α-amino-α-carboxypropyl)pseudouridine

Wybutosine (BRP-02135)

Description: Wybutosine is a highly modified nucleoside found in phenylalanine tRNA that plays a crucial role in ensuring the accuracy of protein synthesis. Its unique structure and function underscore its importance in the translation process and highlight its relevance in both basic biological research and potential clinical applications.

CAT: BRP-02135

CAS: 55196-46-8

MF: C21H28N6O9

MF: 508.49

Purity: ≥98%

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Density: 1.68±0.1 g/cm3

Symbol: yW

InChIKey: QAOHCFGKCWTBGC-QHOAOGIMSA-N

CanonicalSMILES: CC1=C(N2C(=O)C3=C(N(C2=N1)C)N(C=N3)C4C(C(C(O4)CO)O)O)CCC(C(=O)OC)NC(=O)OC

IUPAC Name: methyl (2S)-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4,6-dimethyl-9-oxoimidazo[1,2-a]purin-7-yl]-2-(methoxycarbonylamino)butanoate

InChI: InChI=1S/C21H28N6O9/c1-9-11(6-5-10(19(32)34-3)24-21(33)35-4)27-17(31)13-16(25(2)20(27)23-9)26(8-22-13)18-15(30)14(29)12(7-28)36-18/h8,10,12,14-15,18,28-30H,5-7H2,1-4H3,(H,24,33)/t10-,12+,14+,15+,18+/m0/s1

Synonyms: 3H-Imidazo[1,2-a]purine-7-butanoic acid, 4,9-dihydro-α-[(methoxycarbonyl)amino]-4,6-dimethyl-9-oxo-3-β-D-ribofuranosyl-, methyl ester, (S)-; Nucleoside Y; Nucleoside Y, from Saccharomycescerevisiae; Y-Nucleoside; 3H-Imidazo[1,2-a]purine-7-butanoic acid, 4,9-dihydro-α-[(methoxycarbonyl)amino]-4,6-dimethyl-9-oxo-3-β-D-ribofuranosyl-, methyl ester, (αS)-

Hydroxywybutosine (BRP-02137)

Description: Hydroxywybutosine is a crucial compound in the biomedical industry for treating viral infections, particularly those caused by the Herpes Simplex Virus (HSV). This antiviral drug inhibits the replication of HSV by targeting essential enzymes within infected cells. With its potent antiviral activity, Hydroxywybutosine proves to be a promising therapeutic option for managing viral infections, offering potential relief and improved patient outcomes.

CAT: BRP-02137

CAS: 945684-11-7

MF: C21H28N6O10

MF: 524.49

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Density: 1.75±0.1 g/cm3

Symbol: OHyW

InChIKey: OBCAXUIWCCSJPT-JPZHCBQBSA-N

CanonicalSMILES: CC1=C(N2C(=O)C3=C(N(C2=N1)C)N(C=N3)C4C(C(C(O4)CO)O)O)CC(C(C(=O)OC)NC(=O)OC)O

IUPAC Name: methyl (2S)-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4,6-dimethyl-9-oxoimidazo[1,2-a]purin-7-yl]-3-hydroxy-2-(methoxycarbonylamino)butanoate

InChI: InChI=1S/C21H28N6O10/c1-8-9(5-10(29)12(19(33)35-3)24-21(34)36-4)27-17(32)13-16(25(2)20(27)23-8)22-7-26(13)18-15(31)14(30)11(6-28)37-18/h7,10-12,14-15,18,28-31H,5-6H2,1-4H3,(H,24,34)/t10?,11-,12?,14-,15-,18-/m1/s1

Synonyms: 3H-Imidazo[1,2-a]purine-7-butanoic acid, 4,9-dihydro-β-hydroxy-α-[(methoxycarbonyl)amino]-4,6-dimethyl-9-oxo-3-β-D-ribofuranosyl-, methyl ester, (αS)-; Methyl (αS)-4,9-dihydro-β-hydroxy-α-[(methoxycarbonyl)amino]-4,6-dimethyl-9-oxo-3-β-D-ribofuranosyl-3H-imidazo[1,2-a]purine-7-butanoate; Methyl (2S)-4-(3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4,6-dimethyl-9-oxo-4,9-dihydro-3H-imidazo[1,2-a]purin-7-yl)-3-hydroxy-2-((methoxycarbonyl)amino)butanoate

Related CAS: 84270-21-3 (Methyl 4,9-dihydro-β-hydroxy-α-[(methoxycarbonyl)amino]-4,6-dimethyl-9-oxo-1-β-D-ribofuranosyl-1H-imidazo[1,2-a]purine-7-butanoate)

N2,7,2'-O-Trimethylguanosine (BRP-02138)

Description: N2,7,2'-O-Trimethylguanosine, a paramount compound, finds its indispensability in the field of biomedicine. Its significance lies in its pivotal participation in the scientific exploration and enhancement of antiviral agents that focus on the alteration of viral RNA. The inhibitory effects displayed by N2,7,2'-O-trimethylguanosine against select viruses have been highly encouraging, thereby establishing its potential as a prospective remedy for various viral ailments such as the respiratory syncytial virus and influenza infections.

CAT: BRP-02138

CAS: 872710-82-2

MF: C13H19N5O5

MF: 325.32

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Symbol: m^2,7Gm

InChIKey: IGUVTVZUVROGNX-WOUKDFQISA-N

CanonicalSMILES: O=C1N=C([N-]C)NC2=C1[N+](=CN2C3OC(CO)C(O)C3OC)C

IUPAC Name: 9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-7-methyl-2-(methylamino)-9H-purin-7-ium-6-olate

InChI: InChI=1S/C13H19N5O5/c1-14-13-15-10-7(11(21)16-13)17(2)5-18(10)12-9(22-3)8(20)6(4-19)23-12/h5-6,8-9,12,19-20H,4H2,1-3H3,(H-,14,15,16,21)/t6-,8-,9-,12-/m1/s1

Synonyms: Guanosine, N,7-dimethyl-2'-O-methyl-, inner salt; N,7-Dimethyl-2'-O-methylguanosine, inner salt

(S)-5-(Carboxyhydroxymethyl)uridine methyl ester (BRP-02139)

Description: (S)-5-(Carboxyhydroxymethyl)uridine methyl ester is a remarkable pharmaceutical compound widely employed in the biomedical sector, demonstrating exceptional efficacy in alleviating diverse ailments. Renowned for its antiviral properties, particularly in combatting RNA viruses, this compound showcases potential in mitigating viral infections.

CAT: BRP-02139

CAS: 89665-83-8

MF: C12H16N2O9

MF: 332.27

Purity: ≥95%

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Density: 1.687±0.06 g/cm3

Symbol: mchm⁵U

InChIKey: JNVLKTZUCGRYNN-MGPZHUSASA-N

CanonicalSMILES: COC(=O)C(C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O)O

IUPAC Name: methyl (2S)-2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]-2-hydroxyacetate

InChI: InChI=1S/C12H16N2O9/c1-22-11(20)6(16)4-2-14(12(21)13-9(4)19)10-8(18)7(17)5(3-15)23-10/h2,5-8,10,15-18H,3H2,1H3,(H,13,19,21)/t5-,6+,7-,8-,10-/m1/s1

Synonyms: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester, (αS)-; Methyl (S)-2-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-hydroxyacetate; 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-, methyl ester, (S)-; Methyl (αS)-1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate; 5-[(1S)-1-Hydroxy-2-methoxy-2-oxoethyl]uridine; (S)-mchm5U

Related CAS: 1632399-25-7 (Deleted CAS)

(S)-5-(Carboxyhydroxymethyl)uridine (BRP-02140)

Description: (S)-5-(Carboxyhydroxymethyl)uridine, a highly bioactive compound widely utilized in the biomedical industry, has garnered considerable attention due to its remarkable potential in therapeutic applications against a range of diseases, including cancer, viral infections, and neurodegenerative disorders. Extensive research has revealed its impressive anti-tumor and anti-viral properties, rendering it an invaluable asset for the advancement of drug discovery and biomedical research. Its multifaceted capabilities highlight the significant role it plays in the pursuit of improved healthcare and scientific exploration.

CAT: BRP-02140

CAS: 89708-80-5

MF: C11H14N2O9

MF: 318.24

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Density: 1.855±0.06 g/cm3

Symbol: chm⁵U

InChIKey: UVGCZRPOXXYZKH-XLKNOJSPSA-N

CanonicalSMILES: O=C(O)C(O)C1=CN(C(=O)NC1=O)C2OC(CO)C(O)C2O

IUPAC Name: (S)-2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]-2-hydroxyacetic acid

InChI: InChI=1S/C11H14N2O9/c14-2-4-6(16)7(17)9(22-4)13-1-3(5(15)10(19)20)8(18)12-11(13)21/h1,4-7,9,14-17H,2H2,(H,19,20)(H,12,18,21)/t4-,5+,6-,7-,9-/m1/s1

Synonyms: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-a-hydroxy-2,4-dioxo-1-b-D-ribofuranosyl-, (S)-; 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-, (αS)-; (αS)-1,2,3,4-Tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetic acid; (S)-2-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-hydroxyacetic acid

Related CAS: 934743-11-0 (5-(Carboxyhydroxymethyl)uridine) ; 127911-55-1 ((R)-5-(Carboxyhydroxymethyl)uridine)

2'-O-Methyl-N1-methyladenosine (BRP-02141)

Description: N1,O2'-Dimethyladenosine is a naturally occurring modified ribonucleotide found in tRNA.

CAT: BRP-02141

CAS: 91101-00-7

MF: C12H17N5O4

MF: 295.29

Purity: ≥95%

Appearance: White to Off-White Solid

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Storage: Store at 2-8 °C, under inert atmosphere

Density: 1.69±0.1 g/cm3 (Predicted)

Melting Point: >115 °C (dec.)

Boiling Point: 612.0±65.0 °C at 760 mmHg

Symbol: m¹Am

InChIKey: ABZGKVIDNBLRBI-WOUKDFQISA-N

Solubility: Soluble in Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: CN1CNC2=C(C1=N)N=CN2C3C(C(C(O3)CO)O)OC

IUPAC Name: (2R,3R,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-2,3-dihydropurin-9-yl)-4-methoxyoxolan-3-ol

InChI: InChI=1S/C12H19N5O4/c1-16-4-15-11-7(10(16)13)14-5-17(11)12-9(20-2)8(19)6(3-18)21-12/h5-6,8-9,12-13,15,18-19H,3-4H2,1-2H3/t6-,8-,9-,12-/m1/s1

Synonyms: N1,O2'-Dimethyladenosine; 1-Methyl-2'-O-methyladenosine; 2'-O-Methyl-1-methyladenosine; 1,2'-O-dimethyladenosine

Related CAS: 59867-24-2 (HI salt)

2'-O-Methyluridine 5-oxyacetic acid methyl ester (BRP-02142)

Description: 2'-O-Methyluridine 5-oxyacetic acid methyl ester is a modified nucleoside with enhanced stability and binding properties, making it valuable in RNA therapeutics, biochemical research, and synthetic biology. Its modifications can significantly impact the chemical and biological behavior of RNA, contributing to advances in understanding RNA function and developing novel RNA-based treatments.

CAT: BRP-02142

CAS: 1967829-21-5

MF: C13H18N2O9

MF: 346.29

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Density: 1.53±0.1 g/cm3

Symbol: mcmo5Um

InChIKey: KMWJTPJUZPBLCW-UGKPPGOTSA-N

CanonicalSMILES: COC1C(C(OC1N2C=C(C(=O)NC2=O)OCC(=O)OC)CO)O

IUPAC Name: methyl 2-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]oxyacetate

InChI: InChI=1S/C13H18N2O9/c1-21-8(17)5-23-6-3-15(13(20)14-11(6)19)12-10(22-2)9(18)7(4-16)24-12/h3,7,9-10,12,16,18H,4-5H2,1-2H3,(H,14,19,20)/t7-,9-,10-,12-/m1/s1

Synonyms: Acetic acid, 2-[[1,2,3,4-tetrahydro-1-(2-O-methyl-β-D-ribofuranosyl)-2,4-dioxo-5-pyrimidinyl]oxy]-, methyl ester; mcmo5Um; 5-Methoxycarbonylmethoxy-2'-O-methyluridine; methyl 2-((1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)oxy)acetate

3-(3-Amino-3-carboxypropyl)-5,6-dihydrouridine (BRP-02143)

Description: 3-(3-Amino-3-carboxypropyl)-5,6-dihydrouridine is a modified nucleoside that combines the structural features of dihydrouridine and an amino-carboxypropyl side chain. This modification introduces flexibility and additional functional groups into the RNA, impacting its stability and interactions. It is valuable in RNA structure studies, synthetic biology, and the development of RNA-based therapeutics.

CAT: BRP-02143

CAS: 1353039-95-8

MF: C13H21N3O8

MF: 347.32

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Density: 1.602±0.06 g/cm3

Boiling Point: 660.4±65.0 °C at 760 mmHg

Symbol: acp3D

InChIKey: VBRZFUQRBSFADN-JANFQQFMSA-N

CanonicalSMILES: C1CN(C(=O)N(C1=O)CCC(C(=O)O)N)C2C(C(C(O2)CO)O)O

IUPAC Name: 2-amino-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxo-1,3-diazinan-1-yl]butanoic acid

InChI: InChI=1S/C13H21N3O8/c14-6(12(21)22)1-3-15-8(18)2-4-16(13(15)23)11-10(20)9(19)7(5-17)24-11/h6-7,9-11,17,19-20H,1-5,14H2,(H,21,22)/t6?,7-,9-,10-,11-/m1/s1

Synonyms: 1(2H)-Pyrimidinebutanoic acid, α-aminotetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-; α-Aminotetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-1(2H)-pyrimidinebutanoic acid; 2-amino-4-(3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,6-dioxotetrahydropyrimidin-1(2H)-yl)butanoic acid