Cyclic N6-threonylcarbamoyladenosine (ct6A) is a highly modified nucleoside found in tRNA that plays a critical role in maintaining the accuracy and efficiency of protein synthesis. Its complex structure, involving a cyclic threonine-derived moiety attached to adenosine, contributes to the stability and proper functioning of tRNA. This modification is essential for precise codon recognition and preventing translation errors, highlighting its importance in the overall process of gene expression and cellular function. Research into ct6A and other tRNA modifications provides valuable insights into the mechanisms of translation and has potential applications in genetic, molecular biology, and synthetic biology fields.
Chemical Structure:
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