Nucleosides

2'-Modified Nucleosides
(312/312)
3'-Modified Nucleosides
(175/175)
5'-Modified Nucleosides
(263/263)
Anhydro-Nucleosides
(13/13)
Arabinonucleosides
(34/34)
Base Protected Nucleosides
(244/244)
Halogen Nucleosides
(134/134)
L-Nucleosides
(18/18)
Other Nucleosides
(80/80)
Other Protected Nucleosides
(23/23)
Ribonucleosides
(11/11)
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DiPac-2,6-diamino-2'-OMe-purine-ribose

Description: DiPac-2,6-diamino-2'-OMe-purine-ribose is a modified nucleoside used in oligonucleotide synthesis. This modification consists of a DiPac (diphenoxyacetyl) group attached to the 2-amino and 6-amino positions of purine, and a methyl (Me) group at the 2' position of ribose. It is utilized in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence.
CAT: BRP-00992
Molecular Formula: C27H30N6O8
Molecular Weight: 566.56
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InChIKey: PVYFBCVGORXSLW-CCCLMZFYSA-N
IUPAC Name: N,N'-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-6,9-dihydro-1H-purine-2,6-diyl)bis(2-phenoxyacetamide)
InChI: InChI=1S/C27H30N6O8/c1-38-23-22(37)18(12-34)41-26(23)33-15-28-21-24(29-19(35)13-39-16-8-4-2-5-9-16)31-27(32-25(21)33)30-20(36)14-40-17-10-6-3-7-11-17/h2-11,15,18,22-24,26,34,37H,12-14H2,1H3,(H,29,35)(H2,30,31,32,36)/t18-,22-,23-,24?,26-/m1/s1
Synonyms: DiPac-2,6-diamino-2'-O-methyl-purine-ribose; N2-amino-Pac-2'-O-Me-A(N6-Pac)

N6-iBu-2'-OMe-Ar

Description: N6-iBu-2'-OMe-Ar includes an isobutyl (iBu) group attached to the N6 position of adenine, a methyl (Me) group at the 2' position of ribose, and an aromatic group (Ar). It is utilized in oligonucleotide synthesis and can introduce specific functionalities to the oligonucleotide.
CAT: BRP-00993
CAS: 1084891-36-0
Molecular Formula: C15H21N5O5
Molecular Weight: 351.36
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Density: 1.59±0.1 g/cm3
InChIKey: IRXHRDQDJTWQAV-ORXWAGORSA-N
CanonicalSMILES: CC(C)C(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)OC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]purin-6-yl]-2-methylpropanamide
InChI: InChI=1S/C15H21N5O5/c1-7(2)14(23)19-12-9-13(17-5-16-12)20(6-18-9)15-11(24-3)10(22)8(4-21)25-15/h5-8,10-11,15,21-22H,4H2,1-3H3,(H,16,17,19,23)/t8-,10-,11-,15-/m1/s1
Synonyms: N6-isobutyryl-2'-O-methyl-adenosine; N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)isobutyramide; 2'-O-Methyl-N-(2-methyl-1-oxopropyl)adenosine

N4-Ac-2'-O-Me-5-Me-Cr

Description: N4-Ac-2'-O-Me-5-Me-Cr comprises an acetyl group (Ac) attached to the N4 position of cytosine, a methyl (Me) group at the 2' position of ribose, and a methyl group (Me) at the 5th position of cytosine. It is used in oligonucleotide synthesis and can alter the properties of the resulting oligonucleotide.
CAT: BRP-00994
CAS: 741725-58-6
Molecular Formula: C13H19N3O6
Molecular Weight: 313.31
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Density: 1.53±0.1 g/cm3
InChIKey: DGSGYQXEJYKLEH-DNRKLUKYSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C)C2C(C(C(O2)CO)O)OC
IUPAC Name: N-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C13H19N3O6/c1-6-4-16(13(20)15-11(6)14-7(2)18)12-10(21-3)9(19)8(5-17)22-12/h4,8-10,12,17,19H,5H2,1-3H3,(H,14,15,18,20)/t8-,9-,10-,12-/m1/s1
Synonyms: N4-acetyl-2'-O-methyl-5-methyl-cytidine; N4-Acetyl-5-methyl-2'-O-methyl-cytidine; Cytidine, N-acetyl-5-methyl-2'-O-methyl-

N4-dmf-2'-O-Me-5-Me-Cr

Description: N4-dmf-2'-O-Me-5-Me-Cr contains a dibutylformamidine (dmf) group attached to the N4 position of cytosine, a methyl (Me) group at the 2' position of ribose, and a methyl group (Me) at the 5th position of cytosine. It is utilized in oligonucleotide synthesis and can introduce specific functionalities to the oligonucleotide.
CAT: BRP-00995
Molecular Formula: C14H22N4O5
Molecular Weight: 326.35
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InChIKey: DICOFXKPAKWPIN-PRULPYPASA-N
CanonicalSMILES: O=C1N=C(N=CN(C)C)C(=CN1C2OC(CO)C(O)C2OC)C
IUPAC Name: N'-(1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)-N,N-dimethylformimidamide
InChI: InChI=1S/C14H22N4O5/c1-8-5-18(14(21)16-12(8)15-7-17(2)3)13-11(22-4)10(20)9(6-19)23-13/h5,7,9-11,13,19-20H,6H2,1-4H3/t9-,10-,11-,13-/m1/s1
Synonyms: N4-dimethylformamidine-2'-O-methyl-5-methyl-cytidine
Related CAS: 2920179-30-0 (Z-isomer)

N3-BOM-3'-O-Bz-2'-O-Me-U

Description: N3-BOM-3'-O-Bz-2'-O-Me-U is a modified nucleoside used in oligonucleotide synthesis. This modification consists of a benzyl oxy methyl (BOM) group attached to the N3 position of uracil, a benzoyl (Bz) group at the 3' position of ribose, and a methyl (Me) group at the 2' position of ribose. It is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence.
CAT: BRP-00996
CAS: 2197181-75-0
Molecular Formula: C25H26N2O8
Molecular Weight: 482.49
Purity: ≥98% by HPLC
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Storage: Store at 2-8 °C
Density: 1.39±0.1 g/cm3
Boiling Point: 632.2±65.0 °C at 760 mmHg
InChIKey: DJMBMKCDFWFZOO-JMJGKCIBSA-N
CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)N(C2=O)COCC3=CC=CC=C3)CO)OC(=O)C4=CC=CC=C4
IUPAC Name: [(2R,3R,4R,5R)-5-[2,4-dioxo-3-(phenylmethoxymethyl)pyrimidin-1-yl]-2-(hydroxymethyl)-4-methoxyoxolan-3-yl] benzoate
InChI: InChI=1S/C25H26N2O8/c1-32-22-21(35-24(30)18-10-6-3-7-11-18)19(14-28)34-23(22)26-13-12-20(29)27(25(26)31)16-33-15-17-8-4-2-5-9-17/h2-13,19,21-23,28H,14-16H2,1H3/t19-,21-,22-,23-/m1/s1
Synonyms: N3-Benzyloxymethyl-3'-O-Benzoyl-2'-O-Methyl-uridine

N6-Bz-DMT-2'-O-4'-C-Locked-Ar

Description: N6-Bz-DMT-2'-O-4'-C-Locked-Ar is a modified nucleoside used in oligonucleotide synthesis. This modification consists of a benzoyl (Bz) group attached to the N6 position of adenine, a dimethoxytrityl (DMT) protecting group, a 2'-O modification, and a 4'-carbon locked adenine (Locked-Ar). It is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enhancing stability or enabling interactions with complementary sequences.
CAT: BRP-00997
CAS: 206055-74-5
Molecular Formula: C39H35N5O7
Molecular Weight: 685.72
Purity: ≥98% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at 2-8 °C, in tightly closed container, protected from light and humidity
Density: 1.38±0.1 g/cm3
InChIKey: QKRIAIFSTHOZRG-WBZZMTOKSA-N
CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC45COC(C4O)C(O5)N6C=NC7=C(N=CN=C76)NC(=O)C8=CC=CC=C8
IUPAC Name: N-[9-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]purin-6-yl]benzamide
InChI: InChI=1S/C39H35N5O7/c1-47-29-17-13-27(14-18-29)39(26-11-7-4-8-12-26,28-15-19-30(48-2)20-16-28)50-22-38-21-49-32(33(38)45)37(51-38)44-24-42-31-34(40-23-41-35(31)44)43-36(46)25-9-5-3-6-10-25/h3-20,23-24,32-33,37,45H,21-22H2,1-2H3,(H,40,41,43,46)/t32-,33+,37-,38-/m1/s1
Synonyms: N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-adenosine; N-(9-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-9H-purin-6-yl)benzamide; N-[9-[2,5-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-α-L-lyxofuranosyl]-9H-purin-6-yl]benzamide; 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-O,4'-C-methyleneadenosine; 5'-DMTr-LNA-N6-Bz-A

N4-Ac-DMT-2'-O-4'-C-Locked-Cr

Description: N4-Ac-DMT-2'-O-4'-C-Locked-Cr is a modified nucleoside used in oligonucleotide synthesis. This modification consists of an acetyl (Ac) group attached to the N4 position of cytosine, a dimethoxytrityl (DMT) protecting group, a 2'-O modification, and a 4'-carbon locked cytosine (Locked-Cr). It is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enhancing stability or enabling interactions with complementary sequences.
CAT: BRP-00998
CAS: 1092705-83-3
Molecular Formula: C33H33N3O8
Molecular Weight: 599.64
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Density: 1.34±0.1 g/cm3
InChIKey: MQRGVNKBORBIIG-FHRWSLRQSA-N
CanonicalSMILES: O=C1N=C(C=CN1C2OC3(COC2C3O)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)NC(=O)C
IUPAC Name: N-(1-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
InChI: InChI=1S/C33H33N3O8/c1-21(37)34-27-17-18-36(31(39)35-27)30-28-29(38)32(44-30,19-42-28)20-43-33(22-7-5-4-6-8-22,23-9-13-25(40-2)14-10-23)24-11-15-26(41-3)16-12-24/h4-18,28-30,38H,19-20H2,1-3H3,(H,34,35,37,39)/t28-,29+,30-,32-/m1/s1
Synonyms: N4-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-cytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O,4'-C-methylenecytidine

N2-dmf-DMT-2'-O-4'-C-Locked-Gr

Description: N2-dmf-DMT-2'-O-4'-C-Locked-Gr is a modified nucleoside used in oligonucleotide synthesis. This modification consists of a dibutylformamidine (dmf) group attached to the N2 position of guanine, a dimethoxytrityl (DMT) protecting group, a 2'-O modification, and a 4'-carbon locked guanine (Locked-Gr). It is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enhancing stability or enabling interactions with complementary sequences.
CAT: BRP-00999
CAS: 709641-78-1
Molecular Formula: C35H36N6O7
Molecular Weight: 652.70
Purity: ≥98% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at 2-8 °C, in tightly closed container, protected from light and humidity
Density: 1.38±0.1 g/cm3
Boiling Point: 858.1±75.0 °C at 760 mmHg
InChIKey: GHGCTOJSLHYKAF-GGVMLGSCSA-N
CanonicalSMILES: CN(C)C=NC1=NC2=C(C(=O)N1)N=CN2C3C4C(C(O3)(CO4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O
IUPAC Name: N'-[9-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide
InChI: InChI=1S/C35H36N6O7/c1-40(2)20-37-33-38-30-27(31(43)39-33)36-21-41(30)32-28-29(42)34(48-32,18-46-28)19-47-35(22-8-6-5-7-9-22,23-10-14-25(44-3)15-11-23)24-12-16-26(45-4)17-13-24/h5-17,20-21,28-29,32,42H,18-19H2,1-4H3,(H,38,39,43)/t28-,29+,32-,34-/m1/s1
Synonyms: N2-dimethylformamidine-5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-guanosine; N'-(9-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide; N'-[9-[2,5-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-α-L-lyxofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide; 5'-DMT-2'-O-4'-C-Locked-G(dmf)

N2-iBu-O6-CE-DMT-2'-OMe-Gr

Description: N2-iBu-O6-CE-DMT-2'-OMe-Gr is a modified nucleoside used in oligonucleotide synthesis. It consists of an isobutyl (iBu) group attached to the N2 position of guanine, a cyanoethyl (CE) group attached to the O6 position of guanine, a dimethoxytrityl (DMT) protecting group, a methyl (Me) group at the 2' position of ribose, and a modified guanine (Gr). It is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enhancing stability or enabling interactions with complementary sequences.
CAT: BRP-01000
CAS: 2227139-81-1
Molecular Formula: C39H42N6O8
Molecular Weight: 722.79
Purity: ≥98% by HPLC
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Storage: Store at 2-8 °C, Keep in a dark and dry place
Density: 1.31±0.1 g/cm3
InChIKey: UBLMNMAUYACHGY-GONXPTGJSA-N
CanonicalSMILES: N#CCCOC1=NC(=NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(O)C3OC)NC(=O)C(C)C
IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-6-(2-cyanoethoxy)-9H-purin-2-yl)isobutyramide
InChI: InChI=1S/C39H42N6O8/c1-24(2)35(47)43-38-42-34-31(36(44-38)51-21-9-20-40)41-23-45(34)37-33(50-5)32(46)30(53-37)22-52-39(25-10-7-6-8-11-25,26-12-16-28(48-3)17-13-26)27-14-18-29(49-4)19-15-27/h6-8,10-19,23-24,30,32-33,37,46H,9,21-22H2,1-5H3,(H,42,43,44,47)/t30-,32-,33-,37-/m1/s1
Synonyms: N2-isobutyryl-O6-cyanoethyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-guanosine

DMT-2'-O-Me-5-Me-Cr

Description: DMT-2'-O-Me-5-Me-Cr is a modified nucleoside used in oligonucleotide synthesis. It consists of a dimethoxytrityl (DMT) protecting group, a methyl (Me) group at the 2' position of ribose, and methyl groups (Me) at the 5th position of cytosine. It is utilized in oligonucleotide synthesis to confer specific properties or functionalities to the resulting oligonucleotide, which can be crucial for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-01001
CAS: 2940862-09-7
Molecular Formula: C32H35N3O7
Molecular Weight: 573.64
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Density: 1.28±0.1 g/cm3
Boiling Point: 734.1±70.0 °C at 760 mmHg
InChIKey: QTKGHPBFWOEEHR-NODMTMHWSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OC
IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-5-methylpyrimidin-2-one
InChI: InChI=1S/C32H35N3O7/c1-20-18-35(31(37)34-29(20)33)30-28(40-4)27(36)26(42-30)19-41-32(21-8-6-5-7-9-21,22-10-14-24(38-2)15-11-22)23-12-16-25(39-3)17-13-23/h5-18,26-28,30,36H,19H2,1-4H3,(H2,33,34,37)/t26-,27-,28-,30-/m1/s1
Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyl-cytidine; 5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine

N2-Ac-DMT-2'-OMe-Gr

Description: N2-Ac-DMT-2'-OMe-Gr is a modified nucleoside used in oligonucleotide synthesis. It consists of an acetyl (Ac) group attached to the N2 position of guanine, a dimethoxytrityl (DMT) protecting group, a methyl (Me) group at the 2' position of ribose, and a modified guanine (Gr). It is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enhancing stability or enabling interactions with complementary sequences.
CAT: BRP-01002
CAS: 909033-39-2
Molecular Formula: C34H35N5O8
Molecular Weight: 641.67
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Density: 1.38±0.1 g/cm3
InChIKey: IJLYUZAEWUUOCY-DWCTZGTLSA-N
CanonicalSMILES: O=C1N=C(NC(=O)C)NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(O)C3OC
IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
InChI: InChI=1S/C34H35N5O8/c1-20(40)36-33-37-30-27(31(42)38-33)35-19-39(30)32-29(45-4)28(41)26(47-32)18-46-34(21-8-6-5-7-9-21,22-10-14-24(43-2)15-11-22)23-12-16-25(44-3)17-13-23/h5-17,19,26,28-29,32,41H,18H2,1-4H3,(H2,36,37,38,40,42)/t26-,28-,29-,32-/m1/s1
Synonyms: N2-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-guanosine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylguanosine

N4-dmf-DMT-2'-O-Me-5-Me-Cr

Description: N4-dmf-DMT-2'-O-Me-5-Me-Cr is a modified nucleoside used in oligonucleotide synthesis. It consists of a dibutylformamidine (dmf) group attached to the N4 position of cytosine, a dimethoxytrityl (DMT) protecting group, a methyl (Me) group at the 2' position of ribose, and methyl groups (Me) at the 5th position of cytosine. It is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enhancing stability or enabling interactions with complementary sequences.
CAT: BRP-01003
Molecular Formula: C35H40N4O7
Molecular Weight: 628.71
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InChIKey: BEDTXIPBGSIHIU-WTGZKXAYSA-N
CanonicalSMILES: O=C1N=C(N=CN(C)C)C(=CN1C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(O)C2OC)C
IUPAC Name: N'-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)-N,N-dimethylformimidamide
InChI: InChI=1S/C35H40N4O7/c1-23-20-39(34(41)37-32(23)36-22-38(2)3)33-31(44-6)30(40)29(46-33)21-45-35(24-10-8-7-9-11-24,25-12-16-27(42-4)17-13-25)26-14-18-28(43-5)19-15-26/h7-20,22,29-31,33,40H,21H2,1-6H3/t29-,30-,31-,33-/m1/s1
Synonyms: N4-dimethylformamidine-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyl-cytidine
Related CAS: 2940857-82-7 (Z-isomer)

N4-Ac-DMT-2'-O-propargyl-Cr

Description: N4-Ac-DMT-2'-O-propargyl-Cr is a modified nucleoside used in oligonucleotide synthesis. It consists of an acetyl (Ac) group attached to the N4 position of cytosine, a dimethoxytrityl (DMT) protecting group, and a propargyl group attached to the 2' position of ribose, along with a modified cytosine (Cr). It is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, which can be useful for various applications in molecular biology and biotechnology.
CAT: BRP-01004
CAS: 1498305-50-2
Molecular Formula: C35H35N3O8
Molecular Weight: 625.67
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Density: 1.25±0.1 g/cm3
InChIKey: WTXRMORXMCBUCK-WXQJYUTRSA-N
CanonicalSMILES: O=C1N=C(C=CN1C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(O)C2OCC#C)NC(=O)C
IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
InChI: InChI=1S/C35H35N3O8/c1-5-21-44-32-31(40)29(46-33(32)38-20-19-30(36-23(2)39)37-34(38)41)22-45-35(24-9-7-6-8-10-24,25-11-15-27(42-3)16-12-25)26-13-17-28(43-4)18-14-26/h1,6-20,29,31-33,40H,21-22H2,2-4H3,(H,36,37,39,41)/t29-,31-,32-,33-/m1/s1
Synonyms: N4-Ac-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-cytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propyn-1-ylcytidine

N2-Ac-DMT-2'-O-propargyl-Gr

Description: N2-Ac-DMT-2'-O-propargyl-Gr is a modified nucleoside used in oligonucleotide synthesis. It consists of an acetyl (Ac) group attached to the N2 position of guanine, a dimethoxytrityl (DMT) protecting group, and a propargyl group attached to the 2' position of ribose, along with a modified guanine (Gr). The modification is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enabling various applications in molecular biology and biotechnology.
CAT: BRP-01005
Molecular Formula: C36H35N5O8
Molecular Weight: 665.70
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InChIKey: CEGYIJROMOEVDV-UTBAFCPYSA-N
IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
InChI: InChI=1S/C36H35N5O8/c1-5-19-47-31-30(43)28(49-34(31)41-21-37-29-32(41)39-35(38-22(2)42)40-33(29)44)20-48-36(23-9-7-6-8-10-23,24-11-15-26(45-3)16-12-24)25-13-17-27(46-4)18-14-25/h1,6-18,21,28,30-31,34,43H,19-20H2,2-4H3,(H2,38,39,40,42,44)/t28-,30-,31-,34-/m1/s1
Synonyms: N2-Ac-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-guanosine

3',5'-O-diDMT-2'-O-propargyl-Ur

Description: 3',5'-O-diDMT-2'-O-propargyl-Ur is a modified nucleoside used in oligonucleotide synthesis. It consists of two dimethoxytrityl (DMT) protecting groups attached to the 3' and 5' hydroxyl groups of uracil, and a propargyl group attached to the 2' position of ribose. The modification is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enabling various applications in molecular biology and biotechnology.
CAT: BRP-01006
Molecular Formula: C54H50N2O10
Molecular Weight: 887.00
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InChIKey: FHAVBSPASFBLTH-BUBCVBHASA-N
IUPAC Name: 1-((2R,3R,4R,5R)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChI: InChI=1S/C54H50N2O10/c1-6-35-63-50-49(66-54(38-15-11-8-12-16-38,41-21-29-45(61-4)30-22-41)42-23-31-46(62-5)32-24-42)47(65-51(50)56-34-33-48(57)55-52(56)58)36-64-53(37-13-9-7-10-14-37,39-17-25-43(59-2)26-18-39)40-19-27-44(60-3)28-20-40/h1,7-34,47,49-51H,35-36H2,2-5H3,(H,55,57,58)/t47-,49-,50-,51-/m1/s1
Synonyms: 3',5'-O-di(4,4'-dimethoxytrityl)-2'-O-propargyl-uridine

5'-O-DMTr-2'-O-TBDMS-G(Ac)

Description: 5'-O-DMTr-2'-O-TBDMS-G(Ac) is a modified nucleoside used in oligonucleotide synthesis. It consists of a dimethoxytrityl (DMTr) protecting group at the 5' hydroxyl, a tert-butyldimethylsilyl (TBDMS) group at the 2' position of ribose, and an acetyl (Ac) group attached to guanine. This modification is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enabling various applications in molecular biology and biotechnology.
CAT: BRP-01007
CAS: 1256468-15-1
Molecular Formula: C39H47N5O8Si
Molecular Weight: 741.92
Purity: ≥98% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at 2-8 °C
Density: 1.26±0.1 g/cm3
InChIKey: WMJSMYRPSADDEA-QGGAYTEESA-N
CanonicalSMILES: O=C1N=C(NC(=O)C)NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(O)C3O[Si](C)(C)C(C)(C)C
IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
InChI: InChI=1S/C39H47N5O8Si/c1-24(45)41-37-42-34-31(35(47)43-37)40-23-44(34)36-33(52-53(7,8)38(2,3)4)32(46)30(51-36)22-50-39(25-12-10-9-11-13-25,26-14-18-28(48-5)19-15-26)27-16-20-29(49-6)21-17-27/h9-21,23,30,32-33,36,46H,22H2,1-8H3,(H2,41,42,43,45,47)/t30-,32-,33-,36-/m1/s1
Synonyms: N2-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-guanine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]guanosine; 5'-O-DMT-2'-O-TBDMS-N2-Acetyl-Guanosine

5-Acrylic-5'-DMT-dU

Description: 5-Acrylic-5'-DMT-dU features an acrylic group attached to the 5 position of deoxyuridine, along with a dimethoxytrityl (DMT) protecting group. It is used in oligonucleotide synthesis to introduce specific functionalities, such as for covalent modification or interaction with other biomolecules.
CAT: BRP-01008
CAS: 923023-62-5
Molecular Formula: C33H32N2O9
Molecular Weight: 600.62
Purity: ≥98% by HPLC
Appearance: White, off-white to yellow powder
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Storage: Store at 2-8 °C
Density: 1.369±0.06 g/cm3
InChIKey: GRDHCWWOTJFHSF-CTJHEALJSA-N
CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(CC(O4)N5C=C(C(=O)NC5=O)C=CC(=O)O)O
IUPAC Name: (E)-3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoic acid
InChI: InChI=1S/C33H32N2O9/c1-41-25-13-9-23(10-14-25)33(22-6-4-3-5-7-22,24-11-15-26(42-2)16-12-24)43-20-28-27(36)18-29(44-28)35-19-21(8-17-30(37)38)31(39)34-32(35)40/h3-17,19,27-29,36H,18,20H2,1-2H3,(H,37,38)(H,34,39,40)/b17-8+/t27-,28+,29+/m0/s1
Synonyms: 5-Acrylic-5'-O-(4,4'-dimethoxytrityl)-uridine; (E)-3-(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylic acid; (2E)-3-[1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-2-propenoic acid; (E)-5-(2-Carboxyvinyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine

5-Acrylic-5'-DMT-dU TEA salt

Description: 5-Acrylic-5'-DMT-dU TEA salt is the triethylammonium (TEA) salt form of 5-Acrylic-5'-DMT-dU, typically used to provide better solubility or handling during synthesis.
CAT: BRP-01009
Molecular Formula: C33H32N2O9.C6H15N
Molecular Weight: 701.82
Purity: ≥98% by HPLC
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Storage: Store at 2-8 °C
InChIKey: SKPFWOYCDYVDPX-IZFLFKNXSA-N
CanonicalSMILES: CCN(CC)CC.COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(CC(O4)N5C=C(C(=O)NC5=O)C=CC(=O)O)O
IUPAC Name: (E)-3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoic acid;N,N-diethylethanamine
InChI: InChI=1S/C33H32N2O9.C6H15N/c1-41-25-13-9-23(10-14-25)33(22-6-4-3-5-7-22,24-11-15-26(42-2)16-12-24)43-20-28-27(36)18-29(44-28)35-19-21(8-17-30(37)38)31(39)34-32(35)40;1-4-7(5-2)6-3/h3-17,19,27-29,36H,18,20H2,1-2H3,(H,37,38)(H,34,39,40);4-6H2,1-3H3/b17-8+;/t27-,28+,29+;/m0./s1
Synonyms: (E)-5-(2-Carboxyvinyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine, triethylamine salt; 5-Acrylic-5'-O-(4,4'-dimethoxytrityl)-uridine,triethylamine salt; (E)-3-(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylic acid triethylamine salt; (2E)-3-[1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-2-propenoic acid triethylamine salt
Related CAS: 923023-62-5 (free base)

3',5'-di-O-TBDMS-2'-O-4'-C-Locked-Gr

Description: 3',5'-di-O-TBDMS-2'-O-4'-C-Locked-Gr consists of two tert-butyldimethylsilyl (TBDMS) protecting groups attached to the 3' and 5' hydroxyl groups, along with a 2'-O modificationa, 4'-carbon locked guanine (Locked-Gr). It is used in oligonucleotide synthesis to enhance sequence stability and specific biological activities.
CAT: BRP-01010
CAS: 2940861-48-1
Molecular Formula: C23H41N5O5Si2
Molecular Weight: 523.77
Purity: ≥98% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at RT. Keep container tightly closed. Protect from light.
Density: 1.24±0.1 g/cm3
Boiling Point: 616.6±65.0 °C at 760 mmHg
InChIKey: LDLRSVCCRZMOLN-QIEVIBBNSA-N
CanonicalSMILES: O=C1N=C(N)NC2=C1N=CN2C3OC4(COC3C4O[Si](C)(C)C(C)(C)C)CO[Si](C)(C)C(C)(C)C
IUPAC Name: 2-amino-9-((1R,3R,4R,7S)-7-((tert-butyldimethylsilyl)oxy)-1-(((tert-butyldimethylsilyl)oxy)methyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-1,9-dihydro-6H-purin-6-one
InChI: InChI=1S/C23H41N5O5Si2/c1-21(2,3)34(7,8)31-12-23-11-30-15(16(23)33-35(9,10)22(4,5)6)19(32-23)28-13-25-14-17(28)26-20(24)27-18(14)29/h13,15-16,19H,11-12H2,1-10H3,(H3,24,26,27,29)/t15-,16+,19-,23-/m1/s1
Synonyms: 3',5'-di-O-(t-butyl-dimethylsilyl)-2'-O-4'-C-Locked-guanosine

5'-O-Ts-3'-O-TBDMS-2'-O-4'-C-Locked-Ur

Description: 5'-O-Ts-3'-O-TBDMS-2'-O-4'-C-Locked-Ur features a p-toluenesulfonyl (Ts) group attached to the 5' hydroxyl, a tert-butyldimethylsilyl (TBDMS) group attached to the 3' hydroxyl, and a 2'-O modificationa, a 4'-carbon locked uracil (Locked-Ur). It is used in oligonucleotide synthesis to introduce specific protecting groups or functional moieties.
CAT: BRP-01011
CAS: 2387667-44-7
Molecular Formula: C23H32N2O8SSi
Molecular Weight: 524.66
Purity: ≥98% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at 2-8 °C
Density: 1.33±0.1 g/cm3
InChIKey: YXMSGMAYACMFID-VLVHOKLOSA-N
CanonicalSMILES: O=C1C=CN(C(=O)N1)C2OC3(COC2C3O[Si](C)(C)C(C)(C)C)COS(=O)(=O)C4=CC=C(C=C4)C
IUPAC Name: ((1R,3R,4R,7S)-7-((tert-butyldimethylsilyl)oxy)-3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl 4-methylbenzenesulfonate
InChI: InChI=1S/C23H32N2O8SSi/c1-15-7-9-16(10-8-15)34(28,29)31-14-23-13-30-18(19(23)33-35(5,6)22(2,3)4)20(32-23)25-12-11-17(26)24-21(25)27/h7-12,18-20H,13-14H2,1-6H3,(H,24,26,27)/t18-,19+,20-,23-/m1/s1
Synonyms: 5'-O-Tosyl-3'-O-(t-butyldimethylsilyl)-1-(2'-O,4'-C-methylene-beta-D-ribofuranosyl)-uridineacil; 5'-O-Ts-3'-O-TBDMS-LNA-Ur
* Only for research. Not suitable for any diagnostic or therapeutic use.
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