Nucleotides

3'-OMe-GDP disodium salt

Description: 3'-OMe-GDP disodium salt is a modified nucleotide where the ribose sugar of guanosine has a methyl group at the 3' position. This modification can enhance the stability and alter the binding properties of RNA molecules. 3'-OMe-GDP is used in biochemical and molecular biology research to study RNA synthesis, function, and interactions, as well as in the development of nucleotide-based therapeutics and diagnostic tools.

CAT: BRP-00417

Molecular Formula: C11H15N5Na2O11P2

Molecular Weight: 501.19

Purity: ≥97% by HPLC

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InChIKey: FJVMHSWIOYKOKT-IDIVVRGQSA-L

CanonicalSMILES: COC1C(OC(C1O)N2C=NC3=C2N=C(NC3=O)N)COP(=O)(O)OP(=O)(O)O.Na.Na

IUPAC Name: disodium;((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)methyl hydrogen diphosphate

InChI: InChI=1S/C11H17N5O11P2.2Na/c1-24-7-4(2-25-29(22,23)27-28(19,20)21)26-10(6(7)17)16-3-13-5-8(16)14-11(12)15-9(5)18;;/h3-4,6-7,10,17H,2H2,1H3,(H,22,23)(H2,19,20,21)(H3,12,14,15,18);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

Synonyms: 3'-OMe-GDP; 3'-O-Methylguanosine 5'-(tetrahydrogen diphosphate) disodium salt; 3'-O-methyl-GDP disodium salt; 3'-O-Methylguanosine 5'-diphosphate disodium salt; 3'-O-Methylguanosine diphosphate disodium salt

Related CAS: 78771-34-3 (free acid)

3'-OMe-M7-GDP-IMZ

Description: 3'-OMe-m7-GDP-IMZ is a chemically modified nucleotide. It features a 3'-O-methyl modification on the ribose sugar, a 7-methylguanosine base, and a diphosphate linkage to an imidazole group. This compound is used in biochemical and molecular biology research to study mRNA capping, stability, and interactions with enzymes and proteins involved in nucleotide metabolism. The modifications can enhance stability and provide unique reactivity, making it a valuable tool in the development of nucleotide-based therapies and research into RNA function and processing.

CAT: BRP-00418

Molecular Formula: C15H19N7Na2O10P2

Molecular Weight: 565.28

Purity: ≥80% by HPLC

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InChIKey: UYMNWTSOELIWLF-IDTAVKCVSA-L

CanonicalSMILES: O=C1N=C(N)NC2=C1[N+](=CN2C3OC(COP(=O)([O-])OP(=O)(O)N4C=NC=C4)C(OC)C3O)C.Na.Na

InChI: InChI=1S/C15H21N7O10P2/c1-20-7-22(12-9(20)13(24)19-15(16)18-12)14-10(23)11(29-2)8(31-14)5-30-34(27,28)32-33(25,26)21-4-3-17-6-21/h3-4,6-8,10-11,14,23H,5H2,1-2H3,(H4-,16,18,19,24,25,26,27,28)/p-2/t8-,10-,11-,14-/m1/s1

Synonyms: M7-GDP-IMZ(3'OMe); 3'-O-Methyl-7-methylguanosine-5'-diphosphate imidazole

Related CAS: 2089461-53-8 (free acid)

(2'-OMe-5'-MP-A)pG TEA salt

Description: (2'-OMe-5'-MP-A)pG TEA salt is a modified dinucleotide used in RNA research. It features a 2'-O-methyl modification on the adenosine nucleotide, linked via a phosphate group to guanosine. The triethylammonium (TEA) salt form enhances solubility and stability. This compound is used to study RNA structure, function, and interactions, and is valuable in the development of RNA-based therapeutics and molecular biology applications.

CAT: BRP-00419

Molecular Formula: C21H28N10O14P2 (free acid)

Molecular Weight: 706.46 (free acid)

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-methoxy-2-(phosphonooxymethyl)oxolan-3-yl] hydrogen phosphate;N,N-diethylethanamine

Synonyms: (2'-OMe-5'-MP-A)pG triethylamine salt; 2'-O-Methyl-5'-O-phosphonoadenylyl-(3'→5')-guanosine triethylamine salt; (2'-OMe-5'-MP-A)pG; pA(2'-OMe)mpG TEA salt; 2'-O-Methyladenosine-5'-monophosphate-guanosine triethylammonium salt

Related CAS: 62828-60-8 (free acid) ; 2638447-50-2 (triethylamine salt (1:3)) ; 2894815-57-5 (triethylamine salt (1:2)) ; 2645354-91-0 (ammonium salt)

(2'-OMe-5'-MP-A)pU TEA salt

Description: (2'-OMe-5'-MP-A)pU TEA salt is a modified dinucleotide used in RNA research. It features a 2'-O-methyl modification on the adenosine nucleotide, linked via a phosphate group to uridine. The triethylammonium (TEA) salt form enhances solubility and stability. This compound is utilized to study RNA structure, function, and interactions, and is valuable in the development of RNA-based therapeutics and in molecular biology applications.

CAT: BRP-00420

Molecular Formula: C20H27N7O15P2 (free acid)

Molecular Weight: 667.42 (free acid)

Purity: ≥97% by HPLC

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IUPAC Name: [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-methoxy-2-(phosphonooxymethyl)oxolan-3-yl] [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate;N,N-diethylethanamine

Synonyms: (2'-OMe-5'-MP-A)pU triethylamine salt; ((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-(((((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)-4-methoxytetrahydrofuran-2-yl)methyl dihydrogen phosphate triethylamine salt; (2'-OMe-5'-MP-A)pU; pA(2'-OMe)mpU TEA salt; 2'-O-Methyladenosine-5'-monophosphate-uridine triethylammonium salt

Related CAS: 2956650-76-1 (free acid) ; 2956650-77-2 (triethylamine salt (1:2))

(2'-OMe-5'-MP-G)pG TEA salt

Description: (2'-OMe-5'-MP-G)pG TEA salt is a modified dinucleotide used in RNA research. It features a 2'-O-methyl modification on the guanosine nucleotide, linked via a phosphate group to another guanosine. The triethylammonium (TEA) salt form enhances solubility and stability. This compound is utilized to study RNA structure, function, and interactions, and is valuable in the development of RNA-based therapeutics and in various molecular biology applications.

CAT: BRP-00421

Molecular Formula: C21H28N10O15P2 (free acid)

Molecular Weight: 722.46 (free acid)

Purity: ≥97% by HPLC

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IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-methoxy-2-(phosphonooxymethyl)oxolan-3-yl] hydrogen phosphate;N,N-diethylethanamine

Synonyms: (2'-OMe-5'-MP-G)pG triethylamine salt; ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-(((((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)-4-methoxytetrahydrofuran-2-yl)methyl dihydrogen phosphate triethylamine salt; (2'-OMe-5'-MP-G)pG; 2'-O-Methylguanosine-5'-monophosphate-guanosine triethylammonium salt

Related CAS: 2638447-65-9 (free acid) ; 2638447-66-0 (triethylamine salt (1:3))

ATP Tris salt

Description: ATP Tris salt refers to adenosine-5'-triphosphate (ATP) complexed with tromethamine (Tris) to form a stable salt. This compound is commonly used in biochemical and molecular biology research where the presence of Tris is necessary to maintain a specific pH range in the experimental conditions. The addition of Tris to ATP allows researchers to control the pH of the solution while working with ATP, which is sensitive to changes in pH. This form of ATP is often used in enzymatic assays, protein studies, and other biochemical experiments where the maintenance of a stable pH is critical.

CAT: BRP-00422

Molecular Formula: C10H16N5O13P3 (free acid)

Molecular Weight: 507.18 (free acid)

Purity: ≥97% by HPLC

Appearance: Clear colorless to yellow Liquid

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IUPAC Name: [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate;2-amino-2-(hydroxymethyl)propane-1,3-diol

Synonyms: Adenosine 5'-triphosphate, tris salt; Adenosine, 5'-(tetrahydrogen triphosphate), tris salt; ATP tromethamine salt

Related CAS: 56-65-5 (free base)

GTP Tris salt

Description: GTP Tris salt refers to guanosine-5'-triphosphate (GTP) complexed with tromethamine (Tris) to form a stable salt. Similar to ATP Tris salt, this compound is commonly used in biochemical and molecular biology research where the presence of Tris is necessary to maintain a specific pH range in the experimental conditions. The addition of Tris to GTP allows researchers to control the pH of the solution while working with GTP, which is sensitive to changes in pH. GTP Tris salt finds applications in enzymatic assays, protein studies, and other biochemical experiments where maintaining a stable pH is critical for the desired reactions.

CAT: BRP-00423

Molecular Formula: C10H16N5O14P3 (free acid)

Molecular Weight: 523.18 (free acid)

Purity: ≥97% by HPLC

Appearance: Clear colorless to yellow Liquid

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IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate;2-amino-2-(hydroxymethyl)propane-1,3-diol

Synonyms: GTP tromethamine salt; Guanosine 5'-triphosphate, tris salt; Guanosine 5'-(tetrahydrogen triphosphate) tris salt

Related CAS: 86-01-1 (free base) ; 103192-46-7 (Tris salt (1:3))

CTP Tris salt

Description: CTP Tris salt refers to cytidine-5'-triphosphate (CTP) complexed with tromethamine (Tris) to form a stable salt. Like ATP Tris salt and GTP Tris salt, this compound is commonly used in biochemical and molecular biology research where the presence of Tris is necessary to maintain a specific pH range in the experimental conditions. The addition of Tris to CTP allows researchers to control the pH of the solution while working with CTP, which is sensitive to changes in pH. CTP Tris salt finds applications in enzymatic assays, RNA synthesis, and other biochemical experiments where maintaining a stable pH is critical for the desired reactions.

CAT: BRP-00424

Molecular Formula: C9H16N3O14P3 (free acid)

Molecular Weight: 483.16 (free acid)

Purity: ≥97% by HPLC

Appearance: Clear colorless to yellow Liquid

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IUPAC Name: [[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate;2-amino-2-(hydroxymethyl)propane-1,3-diol

Synonyms: CTP tromethamine salt; Cytidine 5'-triphosphate, tris salt; Cytidine 5'-(tetrahydrogen triphosphate) tris salt

Related CAS: 65-47-4 (free base) ; 102601-32-1 (Tris salt (1:3))

LZCapAG(3'Acm)

Description: LZCapAG(3'Acm), a Cap1 analogue, can be used as an mRNA co-transcription capping reagent. Under the action of T7 polymerase, LZCapAG(3'Acm), NTPs and template DNA are co-transcribed to produce mRNA with 5 'end Cap1 structure. Capped mRNA can be directly translated and expressed in cells and in vivo. It is widely used in in vitro transcription, gene editing, vaccine development, tumor CAR-T therapy, protein replacement therapy and regenerative medicine.

CAT: BRP-00434

Molecular Formula: C35H48N16O24P4 (free acid)

Molecular Weight: 1200.75 (free acid)

Purity: ≥95% by HPLC

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Synonyms: m7(3'Acm)Gppp(2'OMe)ApG; 9-((2R,3R,4S,5S)-4-(acetamidomethyl)-5-((((((((((2R,3R,4R,5R)-3-(((((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3-hydroxytetrahydrofuran-2-yl)-2-amino-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium ammonium salt; LZCapAG(3'Acm) ammonium salt

LZCapAU(3'Acm)

Description: LZCapAU(3'Acm), a Cap1 analogue, can be used as an mRNA co-transcription capping reagent. Under the action of T7 polymerase, LZCapAU(3'Acm), NTPs and template DNA are co-transcribed to produce mRNA with 5 'end Cap1 structure. Capped mRNA can be directly translated and expressed in cells and in vivo. It is widely used in in vitro transcription, gene editing, vaccine development, tumor CAR-T therapy, protein replacement therapy and regenerative medicine.

CAT: BRP-00435

Molecular Formula: C34H47N13O25P4 (free acid)

Molecular Weight: 1161.71 (free acid)

Purity: ≥95% by HPLC

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Synonyms: m7(3'Acm)Gppp(2'OMe)ApU; LZCapAU(3'Acm) ammonium salt; (2R,3R,4R,5R)-2-((((((((((2S,3S,4R,5R)-3-(acetamidomethyl)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl) phosphate ammonium salt

LZCapAG(3'Ma-Biotin)

Description: LZCapAG(3'Ma-Biotin), a Cap1 analog with a Biotin label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-Biotin), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. LZCapAG(3'Ma-Biotin) capped mRNA, with a Biotin label, can bind to streptomycin magnetic beads to explore a variety of biological functions.

CAT: BRP-00436

Molecular Formula: C43H60N18O25P4S (free acid)

Molecular Weight: 1385.01 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-Biotin)Gppp(2'OMe)ApG; LZCapAG(3'Ma-Biotin) ammonium salt; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3R,4R,5R)-2-((((((((((2S,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxy-3-((5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)methyl)tetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl) phosphate ammonium salt

LZCapAG(3'Ma-FAM)

Description: LZCapAG(3'Ma-FAM), a Cap1 analog with an FAM fluorescent label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-FAM), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. LZCapAG(3'Ma-FAM) capped mRNA, with FAM label, can be detected by flow cytometry and fluorescence microscopy, and the distribution of mRNA and LNP can be traced and located.

CAT: BRP-00437

Molecular Formula: C54H56N16O29P4 (free acid)

Molecular Weight: 1517.02 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-FAM)Gppp(2'OMe)ApG; LZCapAG(3'Ma-FAM) ammonium salt; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3R,4R,5R)-2-((((((((((2S,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-3-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxamido)methyl)-4-hydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl) phosphate ammonium salt

LZCapAG(3'Ma-Peg5-FAM)

Description: LZCapAG(3'Ma-Peg5-FAM), a Cap1 analog with an FAM fluorescent label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-Peg5-FAM), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. LZCapAG(3'Ma-Peg5-FAM) capped mRNA, with FAM label, can be detected by flow cytometry and fluorescence microscopy, and the distribution of mRNA and LNP can be traced and located.

CAT: BRP-00438

Molecular Formula: C64H75N17O34P4 (free acid)

Molecular Weight: 1750.28 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-Peg5-FAM)Gppp(2'OMe)ApG; LZCapAG(3'Ma-Peg5-FAM) ammonium salt; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3R,4R,5R)-2-((((((((((2S,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-3-(18-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-3,18-dioxo-5,8,11,14-tetraoxa-2,17-diazaoctadecyl)-4-hydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl) phosphate ammonium salt

LZCapAG(3'Ma-Cy5)

Description: LZCapAG(3'Ma-Cy5), a Cap1 analog with a Cy5 label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-Cy5), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. With LZCapAG(3'Ma-Cy5) capped mRNA, FAM fluorescence can be detected by flow cytometry and fluorescence microscopy, and the distribution of mRNA and LNP can be traced and localized.

CAT: BRP-00439

Molecular Formula: C66H84N18O30P4S2 (free acid)

Molecular Weight: 1797.51 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-Cy5)Gppp(2'OMe)ApG; LZCapAG(3'Ma-Cy5) ammonium salt; 2-(5-(1-(6-((((2S,3S,4R,5R)-2-((((((((((2R,3R,4R,5R)-3-(((((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)oxidophosphoryl)oxy)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxytetrahydrofuran-3-yl)methyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfo-3H-indol-1-ium-2-yl)penta-2,4-dien-1-ylidene)-1-ethyl-3,3-dimethylindoline-5-sulfonate ammonium salt

LZCapAG(3'Ma-Cy7)

Description: LZCapAG(3'Ma-Cy7), a Cap1 analog with a Cy7 label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-Cy7), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. With LZCapAG(3'Ma-Cy7) capped mRNA, FAM fluorescence can be detected by flow cytometry and fluorescence microscopy, and the distribution of mRNA and LNP can be traced and localized.

CAT: BRP-00440

Molecular Formula: C68H86N18O30P4S2 (free acid)

Molecular Weight: 1823.55 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-Cy7)Gppp(2'OMe)ApG; LZCapAG(3'Ma-Cy7) ammonium salt; 2-(7-(1-(6-((((2S,3S,4R,5R)-2-((((((((((2R,3R,4R,5R)-3-(((((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)oxidophosphoryl)oxy)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxytetrahydrofuran-3-yl)methyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfo-3H-indol-1-ium-2-yl)hepta-2,4,6-trien-1-ylidene)-1-ethyl-3,3-dimethylindoline-5-sulfonate ammonium salt

LZCapAG(3'Ma-Cy3)

Description: LZCapAG(3'Ma-Cy3), a Cap1 analog with a Cy3 label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-Cy3), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. With LZCapAG(3'Ma-Cy3) capped mRNA, FAM fluorescence can be detected by flow cytometry and fluorescence microscopy, and the distribution of mRNA and LNP can be traced and localized.

CAT: BRP-00441

Molecular Formula: C64H82N18O30P4S2 (free acid)

Molecular Weight: 1771.47 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-Cy3)Gppp(2'OMe)ApG; LZCapAG(3'Ma-Cy3) ammonium salt; 2-(3-(1-(6-((((2S,3S,4R,5R)-2-((((((((((2R,3R,4R,5R)-3-(((((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)oxidophosphoryl)oxy)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxytetrahydrofuran-3-yl)methyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfo-3H-indol-1-ium-2-yl)allylidene)-1-ethyl-3,3-dimethylindoline-5-sulfonate ammonium salt

N1-Methylpseudouridine-5'-triphosphate tetrasodium salt

Description: N1-Methylpseudouridine-5'-triphosphate tetrasodium salt is a compound used in RNA research and biotechnology. It is derived from pseudouridine, a naturally occurring nucleoside found in RNA. The addition of a methyl group at the N1 position of pseudouridine modifies its structure and properties. This compound is in the form of a tetrasodium salt, enhancing its solubility in aqueous solutions. It is commonly employed in studies investigating RNA structure, function, and RNA-based therapies.

CAT: BRP-00442

CAS: 1931922-77-8

Molecular Formula: C10H13N2Na4O15P3

Molecular Weight: 586.09

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InChIKey: BZQONCYRRIJDOP-ZDKAKZFOSA-J

CanonicalSMILES: CN1C=C(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])O)O.[Na+].[Na+].[Na+].[Na+]

IUPAC Name: tetrasodium;[[[(2R,3S,4R,5S)-3,4-dihydroxy-5-(1-methyl-2,4-dioxopyrimidin-5-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate

InChI: InChI=1S/C10H17N2O15P3.4Na/c1-12-2-4(9(15)11-10(12)16)8-7(14)6(13)5(25-8)3-24-29(20,21)27-30(22,23)26-28(17,18)19;;;;/h2,5-8,13-14H,3H2,1H3,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19);;;;/q;4*+1/p-4/t5-,6-,7-,8+;;;;/m1..../s1

Synonyms: 1-Methylpseudouridine-5'-Triphosphate tetrasodium salt; N1-Methylpseudo-UTP tetrasodium salt; 1-Methylpseudo-UTP tetrasodium salt; N1-Methyl Pseudo UTP tetrasodium salt; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1-methyl-2,4(1H,3H)-pyrimidinedione tetrasodium salt; 1-N-Methyl-pseudo-UTP tetrasodium salt; N1-methyl-Pseudo-UTP sodium salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1-methyl-, sodium salt (1:4); N1-Me-pUTP tetrasodium salt

Related CAS: 1428903-59-6 (free acid)

5-Methylcytidine 5'-triphosphate tetrasodium salt

Description: 5-Methylcytidine 5'-triphosphate tetrasodium salt is a compound used in RNA research and biotechnology. It is a modified nucleotide derived from cytidine, a standard nucleoside found in RNA. The addition of a methyl group at the 5 position of cytidine alters its structure and properties. This compound is in the form of a tetrasodium salt, which enhances its solubility in aqueous solutions. It is commonly utilized in studies investigating RNA modifications, RNA structure, function, and related biotechnological applications.

CAT: BRP-00443

CAS: 1931922-76-7

Molecular Formula: C10H14N3Na4O14P3

Molecular Weight: 585.11

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InChIKey: GOHCEJBAQZRUSR-LDJKHGTPSA-J

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])O)O.[Na+].[Na+].[Na+].[Na+]

IUPAC Name: tetrasodium;[[[(2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate

InChI: InChI=1S/C10H18N3O14P3.4Na/c1-4-2-13(10(16)12-8(4)11)9-7(15)6(14)5(25-9)3-24-29(20,21)27-30(22,23)26-28(17,18)19;;;;/h2,5-7,9,14-15H,3H2,1H3,(H,20,21)(H,22,23)(H2,11,12,16)(H2,17,18,19);;;;/q;4*+1/p-4/t5-,6-,7-,9-;;;;/m1..../s1

Synonyms: 5-Methylcytidine 5'-(Tetrahydrogen Triphosphate) tetrasodium Salt; 5-Methyl-CTP tetrasodium Salt; 5-Me-CTP tetrasodium salt; ((2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate tetrasodium salt

Related CAS: 327174-86-7 (free acid)

N7-Methy-GTP TEA salt

Description: N7-Methyl-GTP TEA salt is a compound utilized in RNA research and biotechnology. It is derived from guanosine triphosphate (GTP), a standard nucleotide found in RNA. The addition of a methyl group at the N7 position of guanosine modifies its structure and properties. The compound is typically formulated as a TEA (triethylammonium) salt, which enhances its solubility in aqueous solutions. This compound is commonly employed in studies investigating RNA modifications, RNA-protein interactions, and related biochemical processes.

CAT: BRP-00444

Molecular Formula: C11H19N5O14P3.xC6H15N

Molecular Weight: 538.22 (free base)

Purity: ≥98% by HPLC

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Synonyms: m7G triethylamine salt; 7-Methyl-GTP triethylamine salt; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-, compd. with N,N-diethylethanamine; 7-Methylguanosine 5'-(tetrahydrogen triphosphate) triethylamine salt; 7-Methylguanosine 5'-triphosphate triethylamine salt; m7-GTP triethylamine salt

Related CAS: 91590-85-1 (free acid)

ATPαS TEA salt

Description: ATPαS TEA salt is a modified form of adenosine triphosphate (ATP), where the oxygen atom in the α-phosphate group is replaced by a sulfur atom. This modification prevents hydrolysis of the phosphate bond. The TEA salt formulation enhances its solubility and stability in aqueous solutions. ATPαS TEA salt is commonly used in biochemical and molecular biology research for studying enzyme kinetics, molecular motors, signal transduction pathways, and other ATP-dependent biological processes.

CAT: BRP-00445

Molecular Formula: C10H16N5O12P3S (free acid)

Molecular Weight: 523.24 (free acid)

Purity: ≥95% by HPLC

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IUPAC Name: [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate;N,N-diethylethanamine

Synonyms: Adenosine, 5'→P''-ester with thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(O)(OH)(SH)), compd. with N,N-diethylethanamine (1:x); Adenosine-5'-O-(1-Thiotriphosphate) TEA salt; ATP-α-S TEA salt; α-Thio-dATP TEA salt; ATP-αS TEA salt

Related CAS: 29220-54-0 (free base) ; 112820-43-6 (TEA salt (1:4))

3'-OMe-GDP disodium salt

3'-OMe-M7-GDP-IMZ

(2'-OMe-5'-MP-A)pG TEA salt

(2'-OMe-5'-MP-A)pU TEA salt

(2'-OMe-5'-MP-G)pG TEA salt

ATP Tris salt

GTP Tris salt

CTP Tris salt

LZCapAG(3'Acm)

LZCapAU(3'Acm)

LZCapAG(3'Ma-Biotin)

LZCapAG(3'Ma-FAM)

LZCapAG(3'Ma-Peg5-FAM)

LZCapAG(3'Ma-Cy5)

LZCapAG(3'Ma-Cy7)

LZCapAG(3'Ma-Cy3)

N1-Methylpseudouridine-5'-triphosphate tetrasodium salt

5-Methylcytidine 5'-triphosphate tetrasodium salt

N7-Methy-GTP TEA salt

ATPαS TEA salt

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