Nucleotides - RNA / BOC Sciences

LZCapAG(3'Acm)

Description: LZCapAG(3'Acm), a Cap1 analogue, can be used as an mRNA co-transcription capping reagent. Under the action of T7 polymerase, LZCapAG(3'Acm), NTPs and template DNA are co-transcribed to produce mRNA with 5 'end Cap1 structure. Capped mRNA can be directly translated and expressed in cells and in vivo. It is widely used in in vitro transcription, gene editing, vaccine development, tumor CAR-T therapy, protein replacement therapy and regenerative medicine.

CAT: BRP-00434

MF: C35H48N16O24P4 (free acid)

MF: 1200.75 (free acid)

Purity: ≥95% by HPLC

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Synonyms: m7(3'Acm)Gppp(2'OMe)ApG; 9-((2R,3R,4S,5S)-4-(acetamidomethyl)-5-((((((((((2R,3R,4R,5R)-3-(((((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3-hydroxytetrahydrofuran-2-yl)-2-amino-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium ammonium salt; LZCapAG(3'Acm) ammonium salt

LZCapAU(3'Acm)

Description: LZCapAU(3'Acm), a Cap1 analogue, can be used as an mRNA co-transcription capping reagent. Under the action of T7 polymerase, LZCapAU(3'Acm), NTPs and template DNA are co-transcribed to produce mRNA with 5 'end Cap1 structure. Capped mRNA can be directly translated and expressed in cells and in vivo. It is widely used in in vitro transcription, gene editing, vaccine development, tumor CAR-T therapy, protein replacement therapy and regenerative medicine.

CAT: BRP-00435

MF: C34H47N13O25P4 (free acid)

MF: 1161.71 (free acid)

Purity: ≥95% by HPLC

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Synonyms: m7(3'Acm)Gppp(2'OMe)ApU; LZCapAU(3'Acm) ammonium salt; (2R,3R,4R,5R)-2-((((((((((2S,3S,4R,5R)-3-(acetamidomethyl)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl) phosphate ammonium salt

LZCapAG(3'Ma-Biotin)

Description: LZCapAG(3'Ma-Biotin), a Cap1 analog with a Biotin label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-Biotin), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. LZCapAG(3'Ma-Biotin) capped mRNA, with a Biotin label, can bind to streptomycin magnetic beads to explore a variety of biological functions.

CAT: BRP-00436

MF: C43H60N18O25P4S (free acid)

MF: 1385.01 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-Biotin)Gppp(2'OMe)ApG; LZCapAG(3'Ma-Biotin) ammonium salt; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3R,4R,5R)-2-((((((((((2S,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxy-3-((5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)methyl)tetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl) phosphate ammonium salt

LZCapAG(3'Ma-FAM)

Description: LZCapAG(3'Ma-FAM), a Cap1 analog with an FAM fluorescent label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-FAM), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. LZCapAG(3'Ma-FAM) capped mRNA, with FAM label, can be detected by flow cytometry and fluorescence microscopy, and the distribution of mRNA and LNP can be traced and located.

CAT: BRP-00437

MF: C54H56N16O29P4 (free acid)

MF: 1517.02 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-FAM)Gppp(2'OMe)ApG; LZCapAG(3'Ma-FAM) ammonium salt; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3R,4R,5R)-2-((((((((((2S,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-3-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxamido)methyl)-4-hydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl) phosphate ammonium salt

LZCapAG(3'Ma-Peg5-FAM)

Description: LZCapAG(3'Ma-Peg5-FAM), a Cap1 analog with an FAM fluorescent label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-Peg5-FAM), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. LZCapAG(3'Ma-Peg5-FAM) capped mRNA, with FAM label, can be detected by flow cytometry and fluorescence microscopy, and the distribution of mRNA and LNP can be traced and located.

CAT: BRP-00438

MF: C64H75N17O34P4 (free acid)

MF: 1750.28 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-Peg5-FAM)Gppp(2'OMe)ApG; LZCapAG(3'Ma-Peg5-FAM) ammonium salt; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3R,4R,5R)-2-((((((((((2S,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-3-(18-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-3,18-dioxo-5,8,11,14-tetraoxa-2,17-diazaoctadecyl)-4-hydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl) phosphate ammonium salt

LZCapAG(3'Ma-Cy5)

Description: LZCapAG(3'Ma-Cy5), a Cap1 analog with a Cy5 label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-Cy5), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. With LZCapAG(3'Ma-Cy5) capped mRNA, FAM fluorescence can be detected by flow cytometry and fluorescence microscopy, and the distribution of mRNA and LNP can be traced and localized.

CAT: BRP-00439

MF: C66H84N18O30P4S2 (free acid)

MF: 1797.51 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-Cy5)Gppp(2'OMe)ApG; LZCapAG(3'Ma-Cy5) ammonium salt; 2-(5-(1-(6-((((2S,3S,4R,5R)-2-((((((((((2R,3R,4R,5R)-3-(((((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)oxidophosphoryl)oxy)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxytetrahydrofuran-3-yl)methyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfo-3H-indol-1-ium-2-yl)penta-2,4-dien-1-ylidene)-1-ethyl-3,3-dimethylindoline-5-sulfonate ammonium salt

LZCapAG(3'Ma-Cy7)

Description: LZCapAG(3'Ma-Cy7), a Cap1 analog with a Cy7 label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-Cy7), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. With LZCapAG(3'Ma-Cy7) capped mRNA, FAM fluorescence can be detected by flow cytometry and fluorescence microscopy, and the distribution of mRNA and LNP can be traced and localized.

CAT: BRP-00440

MF: C68H86N18O30P4S2 (free acid)

MF: 1823.55 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-Cy7)Gppp(2'OMe)ApG; LZCapAG(3'Ma-Cy7) ammonium salt; 2-(7-(1-(6-((((2S,3S,4R,5R)-2-((((((((((2R,3R,4R,5R)-3-(((((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)oxidophosphoryl)oxy)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxytetrahydrofuran-3-yl)methyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfo-3H-indol-1-ium-2-yl)hepta-2,4,6-trien-1-ylidene)-1-ethyl-3,3-dimethylindoline-5-sulfonate ammonium salt

LZCapAG(3'Ma-Cy3)

Description: LZCapAG(3'Ma-Cy3), a Cap1 analog with a Cy3 label, can be used as an mRNA cotranscription capping agent. Under the action of T7 polymerase, LZCapAG(3'Ma-Cy3), NTPs and template DNA were co-transcribed to produce mRNA with 5 'Cap 1 structure, and the capped mRNA could be directly translated and expressed in cells and in vivo, with excellent expression efficiency. With LZCapAG(3'Ma-Cy3) capped mRNA, FAM fluorescence can be detected by flow cytometry and fluorescence microscopy, and the distribution of mRNA and LNP can be traced and localized.

CAT: BRP-00441

MF: C64H82N18O30P4S2 (free acid)

MF: 1771.47 (free acid)

Purity: ≥90% by HPLC

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Synonyms: m7(3'Ma-Cy3)Gppp(2'OMe)ApG; LZCapAG(3'Ma-Cy3) ammonium salt; 2-(3-(1-(6-((((2S,3S,4R,5R)-2-((((((((((2R,3R,4R,5R)-3-(((((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)oxidophosphoryl)oxy)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxytetrahydrofuran-3-yl)methyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfo-3H-indol-1-ium-2-yl)allylidene)-1-ethyl-3,3-dimethylindoline-5-sulfonate ammonium salt

N1-Methylpseudouridine-5'-triphosphate tetrasodium salt

Description: N1-Methylpseudouridine-5'-triphosphate tetrasodium salt is a compound used in RNA research and biotechnology. It is derived from pseudouridine, a naturally occurring nucleoside found in RNA. The addition of a methyl group at the N1 position of pseudouridine modifies its structure and properties. This compound is in the form of a tetrasodium salt, enhancing its solubility in aqueous solutions. It is commonly employed in studies investigating RNA structure, function, and RNA-based therapies.

CAT: BRP-00442

CAS: 1931922-77-8

MF: C10H13N2Na4O15P3

MF: 586.09

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InChIKey: BZQONCYRRIJDOP-ZDKAKZFOSA-J

CanonicalSMILES: CN1C=C(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])O)O.[Na+].[Na+].[Na+].[Na+]

IUPAC Name: tetrasodium;[[[(2R,3S,4R,5S)-3,4-dihydroxy-5-(1-methyl-2,4-dioxopyrimidin-5-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate

InChI: InChI=1S/C10H17N2O15P3.4Na/c1-12-2-4(9(15)11-10(12)16)8-7(14)6(13)5(25-8)3-24-29(20,21)27-30(22,23)26-28(17,18)19;;;;/h2,5-8,13-14H,3H2,1H3,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19);;;;/q;4*+1/p-4/t5-,6-,7-,8+;;;;/m1..../s1

Synonyms: 1-Methylpseudouridine-5'-Triphosphate tetrasodium salt; N1-Methylpseudo-UTP tetrasodium salt; 1-Methylpseudo-UTP tetrasodium salt; N1-Methyl Pseudo UTP tetrasodium salt; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1-methyl-2,4(1H,3H)-pyrimidinedione tetrasodium salt; 1-N-Methyl-pseudo-UTP tetrasodium salt; N1-methyl-Pseudo-UTP sodium salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1-methyl-, sodium salt (1:4); N1-Me-pUTP tetrasodium salt

Related CAS: 1428903-59-6 (free acid)

5-Methylcytidine 5'-triphosphate tetrasodium salt

Description: 5-Methylcytidine 5'-triphosphate tetrasodium salt is a compound used in RNA research and biotechnology. It is a modified nucleotide derived from cytidine, a standard nucleoside found in RNA. The addition of a methyl group at the 5 position of cytidine alters its structure and properties. This compound is in the form of a tetrasodium salt, which enhances its solubility in aqueous solutions. It is commonly utilized in studies investigating RNA modifications, RNA structure, function, and related biotechnological applications.

CAT: BRP-00443

CAS: 1931922-76-7

MF: C10H14N3Na4O14P3

MF: 585.11

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InChIKey: GOHCEJBAQZRUSR-LDJKHGTPSA-J

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])O)O.[Na+].[Na+].[Na+].[Na+]

IUPAC Name: tetrasodium;[[[(2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate

InChI: InChI=1S/C10H18N3O14P3.4Na/c1-4-2-13(10(16)12-8(4)11)9-7(15)6(14)5(25-9)3-24-29(20,21)27-30(22,23)26-28(17,18)19;;;;/h2,5-7,9,14-15H,3H2,1H3,(H,20,21)(H,22,23)(H2,11,12,16)(H2,17,18,19);;;;/q;4*+1/p-4/t5-,6-,7-,9-;;;;/m1..../s1

Synonyms: 5-Methylcytidine 5'-(Tetrahydrogen Triphosphate) tetrasodium Salt; 5-Methyl-CTP tetrasodium Salt; 5-Me-CTP tetrasodium salt; ((2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate tetrasodium salt

Related CAS: 327174-86-7 (free acid)

N7-Methy-GTP TEA salt

Description: N7-Methyl-GTP TEA salt is a compound utilized in RNA research and biotechnology. It is derived from guanosine triphosphate (GTP), a standard nucleotide found in RNA. The addition of a methyl group at the N7 position of guanosine modifies its structure and properties. The compound is typically formulated as a TEA (triethylammonium) salt, which enhances its solubility in aqueous solutions. This compound is commonly employed in studies investigating RNA modifications, RNA-protein interactions, and related biochemical processes.

CAT: BRP-00444

MF: C11H19N5O14P3.xC6H15N

MF: 538.22 (free base)

Purity: ≥98% by HPLC

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Synonyms: m7G triethylamine salt; 7-Methyl-GTP triethylamine salt; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-, compd. with N,N-diethylethanamine; 7-Methylguanosine 5'-(tetrahydrogen triphosphate) triethylamine salt; 7-Methylguanosine 5'-triphosphate triethylamine salt; m7-GTP triethylamine salt

Related CAS: 91590-85-1 (free acid)

ATPαS TEA salt

Description: ATPαS TEA salt is a modified form of adenosine triphosphate (ATP), where the oxygen atom in the α-phosphate group is replaced by a sulfur atom. This modification prevents hydrolysis of the phosphate bond. The TEA salt formulation enhances its solubility and stability in aqueous solutions. ATPαS TEA salt is commonly used in biochemical and molecular biology research for studying enzyme kinetics, molecular motors, signal transduction pathways, and other ATP-dependent biological processes.

CAT: BRP-00445

MF: C10H16N5O12P3S (free acid)

MF: 523.24 (free acid)

Purity: ≥95% by HPLC

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IUPAC Name: [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate;N,N-diethylethanamine

Synonyms: Adenosine, 5'→P''-ester with thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(O)(OH)(SH)), compd. with N,N-diethylethanamine (1:x); Adenosine-5'-O-(1-Thiotriphosphate) TEA salt; ATP-α-S TEA salt; α-Thio-dATP TEA salt; ATP-αS TEA salt

Related CAS: 29220-54-0 (free base) ; 112820-43-6 (TEA salt (1:4))

GTP-αS

Description: GTP-αS is a modified form of guanosine triphosphate (GTP). In GTP-αS, the oxygen atom in the α-phosphate group of GTP is replaced by a sulfur atom, resulting in a non-hydrolyzable analog of GTP. This modification allows GTP-αS to mimic the structure of GTP while preventing its hydrolysis. GTP-αS is commonly utilized in biochemical and molecular biology research to investigate GTP-dependent processes such as signal transduction, GTPase activity, and protein synthesis, among others.

CAT: BRP-00446

CAS: 71376-96-0

MF: C10H16N5O13P3S

MF: 539.25

Purity: ≥95% by HPLC

Appearance: Colourless to slightly yellow liquid

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Density: 2.68±0.1 g/cm3

InChIKey: YRUWXBKVSXSSGS-AESZWTTRSA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=S)(O)OP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N

IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H16N5O13P3S/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(26-9)1-25-31(24,32)28-30(22,23)27-29(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,32)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-,31?/m1/s1

Synonyms: Guanosine, 5'→P''-ester with thiotriphosphoric acid; GTPαS; Guanosine-5'-Rp-Alpha-Thio-Triphosphate; Guanosine 5'-O-(1-thiotriphosphate); Guanosine 5'-O-thiotriphosphate; Alpha Thiol GTP (1-Thio-GTP)

Related CAS: 81570-51-6 (S-isomer)

GTP-αS TEA salt

Description: GTP-αS TEA salt is a modified form of guanosine triphosphate (GTP) where the oxygen atom in the α-phosphate group is replaced by a sulfur atom, making it a non-hydrolyzable analog of GTP. This modification allows GTP-αS to mimic the structure of GTP while preventing its hydrolysis. The TEA salt formulation enhances the solubility and stability of GTP-αS in aqueous solutions. GTP-αS TEA salt is commonly used in biochemical and molecular biology research to study GTP-dependent processes, such as signal transduction, GTPase activity, and protein synthesis.

CAT: BRP-00447

MF: C10H16N5O13P3S (free acid)

MF: 539.25 (free acid)

Purity: ≥95% by HPLC

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IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate;N,N-diethylethanamine

Synonyms: Guanosine, 5'→P''-ester with thiotriphosphoric acid TEA salt; GTPαS TEA salt; Guanosine-5'-Rp-Alpha-Thio-Triphosphate TEA salt; Guanosine 5'-O-(1-thiotriphosphate) TEA salt; Guanosine 5'-O-thiotriphosphate TEA salt

Related CAS: 71376-96-0 (free base)

CTP-αS

Description: CTP-αS is a modified form of cytidine triphosphate (CTP). In CTP-αS, the oxygen atom in the α-phosphate group of CTP is replaced by a sulfur atom, resulting in a non-hydrolyzable analog of CTP. This modification allows CTP-αS to mimic the structure of CTP while preventing its hydrolysis. CTP-αS is commonly used in biochemical and molecular biology research to study CTP-dependent processes, such as RNA synthesis, RNA splicing, and other nucleic acid-related processes.

CAT: BRP-00448

CAS: 110972-40-2

MF: C9H16N3O13P3S

MF: 499.22

Purity: ≥95% by HPLC

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Storage: Store at -20 °C

Density: 2.44±0.1 g/cm3

Boiling Point: 805.3±75.0 °C at 760 mmHg

InChIKey: MBIHBEVUNFGMSS-NOUWQNLYSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=S)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H16N3O13P3S/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(23-8)3-22-28(21,29)25-27(19,20)24-26(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,29)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-,28?/m1/s1

Synonyms: Cytidine, 5'→P''-ester with thiotriphosphoric acid; Cytidine-5'-O-(1-thiotriphosphate); CTPαS; Alpha Thiol CTP (1-Thio-CTP)

Related CAS: 118353-34-7 (S-isomer) ; 118374-59-7 (R-isomer)

UTP-αS

Description: UTP-αS is a modified form of uridine triphosphate (UTP). In UTP-αS, the oxygen atom in the α-phosphate group of UTP is replaced by a sulfur atom, creating a non-hydrolyzable analog of UTP. This modification allows UTP-αS to mimic the structure of UTP while preventing its hydrolysis. UTP-αS is commonly utilized in biochemical and molecular biology research to study UTP-dependent processes, such as RNA synthesis, RNA editing, and other nucleic acid-related functions.

CAT: BRP-00449

CAS: 18875-71-3

MF: C9H15N2O14P3S

MF: 500.21

Purity: ≥95% by HPLC

Appearance: Colorless to slightly yellow liquid

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Storage: Store at -20 °C

Density: 2.030±0.06 g/cm3

InChIKey: BWPNYQWDXHLOGU-NOUWQNLYSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=S)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(23-8)3-22-28(21,29)25-27(19,20)24-26(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,29)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-,28?/m1/s1

Synonyms: Alpha Thiol UTP; 1-Thio-UTP; Uridine-5'-O-(1-Thiotriphosphate); Uridine, 5'→P''-ester with thiotriphosphoric acid; Thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(S)(OH)2), 5'-monoester with uridine; UTPαS

Related CAS: 71214-29-4 (S-isomer)

UTPαS TEA salt

Description: UTPαS TEA salt is a modified form of uridine triphosphate (UTP) where the oxygen atom in the α-phosphate group is replaced by a sulfur atom, rendering it a non-hydrolyzable analog of UTP. This modification allows UTPαS to mimic the structure of UTP while preventing its hydrolysis. The TEA salt formulation enhances the solubility and stability of UTPαS in aqueous solutions. UTPαS TEA salt is commonly used in biochemical and molecular biology research to study UTP-dependent processes, such as RNA synthesis, RNA editing, and other nucleic acid-related functions.

CAT: BRP-00450

MF: C9H15N2O14P3S (free acid)

MF: 500.21 (free acid)

Purity: ≥95% by HPLC

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Storage: Store at -20 °C

IUPAC Name: [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate;N,N-diethylethanamine

Synonyms: Alpha Thiol UTP TEA salt; 1-Thio-UTP TEA salt; Uridine-5'-O-(1-Thiotriphosphate) TEA salt; Uridine, 5'→P''-ester with thiotriphosphoric acid TEA salt; UTP-αS TEA salt

Related CAS: 18875-71-3 (free base)

(3'Ome)GTP-αS

Description: (3'Ome)GTP-αS is a modified form of guanosine triphosphate (GTP). In this modification, the oxygen atom in the α-phosphate group of GTP is replaced by a sulfur atom, creating a non-hydrolyzable analog of GTP. Additionally, 3'Ome indicates the addition of a methyl group at the 3' position of the ribose sugar. This modification can alter the stability and specificity of the nucleotide in various biochemical and molecular biology experiments. GTP-αS analogs, including (3'Ome)GTP-αS, are widely used in studies involving GTP-dependent processes, such as GTPase activity, signal transduction, and protein synthesis, among others.

CAT: BRP-00451

MF: C11H18N5O13P3S

MF: 553.27

Purity: ≥95% by HPLC

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Synonyms: 3'-O-Methyl-GTPαS; 3'-O-Methyl-Guanosine-5'-Rp-Alpha-Thio-Triphosphate; 3'-O-Methyl-Guanosine 5'-O-(1-thiotriphosphate); 3'-O-Methyl-Guanosine 5'-O-thiotriphosphate; (3'Ome) guanosine-5'-O-(1-thiotriphosphate)

(3'Ome)GTP-αS TEA salt

Description: (3'Ome)GTP-αS TEA salt is a modified form of guanosine triphosphate (GTP). In this modification, the α position of guanosine triphosphate (GTP) is altered by replacing the oxygen atom with a sulfur atom, creating a non-hydrolyzable analog of GTP. Additionally, 3'Ome indicates the addition of a methyl group at the 3' position of the ribose sugar. The TEA salt formulation enhances the solubility and stability of (3'Ome)GTP-αS in aqueous solutions, making it suitable for various biochemical and molecular biology experiments involving GTP-dependent processes, such as GTPase activity, signal transduction, and protein synthesis.

CAT: BRP-00452

MF: C11H18N5O13P3S (free acid)

MF: 553.27 (free acid)

Purity: ≥95% by HPLC

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Storage: Store at -20 °C

Synonyms: 3'-O-Methyl-GTPαS TEA salt; 3'-O-Methyl-Guanosine-5'-Rp-Alpha-Thio-Triphosphate TEA salt; 3'-O-Methyl-Guanosine 5'-O-(1-thiotriphosphate) TEA salt; 3'-O-Methyl-Guanosine 5'-O-thiotriphosphate TEA salt

(3'Ome)GTP TEA salt

Description: 3'-O-Methylguanosine-5'-triphosphate (3'OmeGTP) TEA salt is a chemically modified nucleotide used in various molecular biology and biochemical applications. This compound features a methyl group at the 3' position of the guanosine ribose sugar and is provided as a triethylammonium (TEA) salt for enhanced solubility. 3'OmeGTP serves as a substrate for RNA polymerases during in vitro transcription, allowing for the incorporation of 3'-O-methylguanine into RNA molecules. This modification is valuable in studies of RNA structure and function, and in the development of RNA-based therapeutics and research tools.

CAT: BRP-00453

MF: C11H18N5O14P3 (free acid)

MF: 537.21 (free acid)

Purity: ≥95% by HPLC

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IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-3-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate;N,N-diethylethanamine

Synonyms: (3'Ome)GTP TEA salt; 3'-O-Methylguanosine-5'-triphosphate TEA salt; 3'-O-Methylguanosine 5'-(tetrahydrogen triphosphate) TEA salt; 3'-O-methyl-GTP TEA salt; 3'-O-Methylguanosine triphosphate TEA salt

Related CAS: 61556-45-4 (free base)