Nucleotides

Description: 5-Aza CTP Sodium Salt is a modified nucleotide analog where cytidine is replaced with 5-azacytidine. This modification is commonly used in RNA research and epigenetics studies due to its ability to inhibit DNA methylation. The addition of a sodium salt improves its solubility and stability.

CAT: BRP-00659

Molecular Formula: C8H15N4O14P3 (free acid)

Molecular Weight: 484.14 (free acid)

Purity: ≥97%

Description: 2-NH2-ATP Sodium Salt is a nucleotide analog with an amino group (NH2) attached at the 2nd position of the adenine base. This modification can be utilized in various biochemical assays, such as kinase assays and nucleic acid labeling, due to its altered properties compared to standard ATP. The sodium salt form enhances its solubility in aqueous solutions.

CAT: BRP-00660

Molecular Formula: C10H17N6O13P3 (free acid)

Molecular Weight: 522.20 (free acid)

Purity: >98%

Description: 2'-O-MOE-ATP Sodium Salt is a modified form of adenosine triphosphate (ATP) with a 2'-O-methyl (MOE) group attached to the ribose sugar moiety. This modification increases the stability of ATP against enzymatic degradation, making it useful in various molecular biology applications, including RNA synthesis and RNA-protein interaction studies. The addition of a sodium salt enhances its solubility and stability.

CAT: BRP-00661

Molecular Formula: C13H32N5O14P3 (free acid)

Molecular Weight: 565.26 (free acid)

Purity: >98%

Description: 3-Me-5-OMe-UTP Sodium Salt is a nucleotide analog with a methyl group (Me) attached at the 3rd position and a methoxy group (OMe) at the 5th position of the uracil base. This modification is often used in RNA research for labeling and in vitro transcription due to its altered properties compared to standard UTP. The sodium salt form improves its solubility in aqueous solutions.

CAT: BRP-00662

Molecular Formula: C11H19N2O16P3 (free acid)

Molecular Weight: 528.19 (free acid)

Purity: >98%

Description: N1-Me-pUDP sodium salt is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA.

CAT: BRP-00663

Molecular Formula: C10H13N2O12P2 (free acid)

Molecular Weight: 417.19 (free acid)

Purity: ＞95%

Description: 3'-OMe-m7GMP Ammonium Salt is a modified form of guanosine monophosphate (GMP) where a methoxy group (OMe) is attached at the 3rd position and a 7-methylguanosine (m7G) cap is present. This modification is commonly used in RNA research and mRNA capping studies due to its resemblance to the structure of eukaryotic mRNA caps. The ammonium salt improves its solubility and stability in aqueous solutions.

CAT: BRP-00664

Molecular Formula: C12H18N5O8P (free acid)

Molecular Weight: 391.27 (free acid)

Purity: >98%

Description: 5-Aminoallyl-UTP Sodium Salt is a modified form of uridine triphosphate (UTP) where an aminoallyl group is attached at the 5th position of the uracil base. This modification allows for the labeling of RNA molecules with amine-reactive dyes for various applications, including microarray analysis and RNA sequencing. The sodium salt form enhances its solubility and stability.

CAT: BRP-00665

Molecular Formula: C12H20N3O15P3 (free acid)

Molecular Weight: 539.22 (free acid)

Purity: >98%

Description: N1-Me-pUMP Sodium Salt is a modified form of uridine monophosphate (UMP) where a methyl group (Me) is attached to the N1 position of the uracil base. This modification can affect the activity of enzymes involved in nucleic acid metabolism and signaling pathways. The sodium salt form improves its solubility and stability.

CAT: BRP-00666

Molecular Formula: C10H15N2O9P (free acid)

Molecular Weight: 338.21 (free acid)

Purity: >95%

Description: ADP-heptose is a molecule composed of adenosine diphosphate (ADP) linked to a heptose sugar molecule. Heptose sugars are commonly found in bacterial lipopolysaccharides (LPS) and are crucial for the structural integrity and immunogenicity of these molecules. ADP-heptose is involved in the biosynthesis of LPS, which is an essential component of the outer membrane of Gram-negative bacteria. LPS plays a critical role in bacterial virulence and host-pathogen interactions. Studying ADP-heptose can provide insights into bacterial physiology, pathogenesis, and potential targets for antibiotic development.

CAT: BRP-00667

CAS: 322640-28-8

Molecular Formula: C17H27N5O16P2

Molecular Weight: 619.37

Purity: ≥95%

Description: pUTP Tris salt is a nucleotide analog of uridine triphosphate (UTP) wherein uracil is substituted with pseudouridine (Ψ). This modification mimics natural RNA structures and functions, enhancing its utility in RNA-related research. The addition of Tris salt improves its solubility and stability, making it suitable for various molecular biology applications. Common uses include RNA labeling, in vitro transcription assays, and studying RNA modifications, offering insights into RNA biology and potential therapeutic avenues.

CAT: BRP-00668

Molecular Formula: C9H15N2O15P3 (free acid)

Molecular Weight: 484.14 (free acid)

Purity: >99%

Description: 2'-O-4'-C-Locked-m7GMP sodium salt is a modified form of guanosine monophosphate (GMP) where a locked nucleic acid (LNA) modification is incorporated at the 2' position and a 4'-carbon linkage (4'-C) is present. Additionally, it contains a 7-methylguanosine (m7G) cap. The locked nucleic acid modification enhances the compound's stability and hybridization affinity, making it useful for various biochemical applications, particularly in RNA research. The addition of a sodium salt enhances the compound's solubility and stability in aqueous solutions. This modified nucleotide is commonly used in enzymatic reactions, RNA capping studies, and investigations of mRNA processing and translation mechanisms due to its resemblance to the structure of eukaryotic mRNA caps.

CAT: BRP-00669

Molecular Formula: C12H16N5O8P (free acid)

Molecular Weight: 389.26 (free acid)

Purity: >98%

Description: 2'-O-4'-C-Locked-m7GMP Ammonium salt is a modified derivative of guanosine monophosphate (GMP) where a locked nucleic acid (LNA) modification is incorporated at the 2' position and a 4'-carbon linkage (4'-C) is present, along with a 7-methylguanosine (m7G) cap. The locked nucleic acid modification enhances the stability and hybridization affinity of the compound, making it valuable in biochemical applications, especially in RNA research. The inclusion of an ammonium salt further improves its solubility and stability, particularly in aqueous solutions. This modified nucleotide is commonly used in various molecular biology techniques, such as enzymatic reactions, RNA capping studies, and investigations into mRNA processing and translation mechanisms. Its structure closely resembles that of eukaryotic mRNA caps, making it a useful tool for studying mRNA-related processes in biological systems.

CAT: BRP-00670

Molecular Formula: C12H16N5O8P (free acid)

Molecular Weight: 389.26 (free acid)

Purity: >98%

Description: 2'-O-4'-C-Locked-GMP TEA Salt is a modified form of guanosine monophosphate (GMP) where a locked nucleic acid (LNA) modification is incorporated at the 2' position and a 4'-carbon linkage (4'-C) is present. This modification enhances the stability and hybridization affinity of the nucleotide, making it useful for various biochemical applications, particularly in RNA research. The addition of a TEA (triethylammonium) salt further improves its solubility and stability in aqueous solutions. Common uses of 2'-O-4'-C-Locked-GMP TEA Salt include enzymatic reactions, RNA capping studies, and investigations into mRNA processing and translation mechanisms. Its structure closely resembles that of eukaryotic mRNA caps, making it a valuable tool for studying mRNA-related processes in biological systems.

CAT: BRP-00671

Molecular Formula: C11H14N5O8P (free acid)

Molecular Weight: 375.23 (free acid)

Purity: >98%

Description: 2'-O-4'-C-Locked-m7GMP TEA Salt is a modified form of guanosine monophosphate (GMP) where a locked nucleic acid (LNA) modification is incorporated at the 2' position and a 4'-carbon linkage (4'-C) is present. Additionally, it contains a 7-methylguanosine (m7G) cap. The locked nucleic acid modification enhances the compound's stability and hybridization affinity, making it useful for various biochemical applications, particularly in RNA research. The addition of a TEA (triethylammonium) salt enhances its solubility and stability in aqueous solutions. This modified nucleotide is commonly used in enzymatic reactions, RNA capping studies, and investigations of mRNA processing and translation mechanisms due to its resemblance to the structure of eukaryotic mRNA caps.

CAT: BRP-00672

Molecular Formula: C12H16N5O8P (free acid)

Molecular Weight: 389.26 (free acid)

Purity: >98%

Description: 3'-OMe-m7GMP sodium salt is a chemical compound derived from guanosine monophosphate (GMP) where a methyl group is added to the 3' position and a 7-methylguanosine (m7G) cap is present. This modification mimics the structure of the 5' cap found in eukaryotic mRNA, which plays a crucial role in mRNA stability, translation initiation, and mRNA splicing. The addition of a sodium salt enhances the compound's solubility and stability, making it suitable for various biochemical applications, particularly in RNA research. This modified nucleotide is commonly used as a substrate in enzymatic reactions, RNA capping studies, and as a tool for investigating mRNA processing and translation mechanisms.

CAT: BRP-00673

Molecular Formula: C12H18N5O8P (free acid)

Molecular Weight: 391.27 (free acid)

Purity: >98%

Description: Cy5-UTP sodium salt is a modified form of uridine triphosphate (UTP) with a Cyanine 5 (Cy5) fluorescent dye attached to the 5th position of the uracil base. This modification enables the labeling of RNA molecules during transcription, allowing for their visualization and detection in various biological assays. The addition of a sodium salt enhances the compound's solubility and stability, making it suitable for applications in molecular biology and biochemistry. Cy5-UTP sodium salt is commonly used in RNA labeling techniques, fluorescence in situ hybridization (FISH) assays, real-time monitoring of RNA synthesis and degradation pathways, and the visualization of RNA localization within cells. This compound serves as a valuable tool for studying gene expression, RNA trafficking, and other RNA-related processes in biological systems, contributing significantly to our understanding of cellular function and regulation.

CAT: BRP-00674

Molecular Formula: C45H58N5O22P3S2 (free acid)

Molecular Weight: 1178.01 (free acid)

Purity: >95%

Description: 5-OMe-UTP TEA Salt is a modified form of uridine triphosphate (UTP) where a methoxy (OMe) group is attached to the 5th position of the uracil base. This modification enables UTP to be utilized in various biochemical applications. Additionally, the compound exists in the form of a TEA (triethylammonium) salt, enhancing its solubility and stability in aqueous solutions. 5-OMe-UTP TEA Salt is commonly employed in molecular biology research for RNA labeling, RNA-protein interaction studies, and in vitro transcription assays. Its binding during transcription allows for the specific detection and manipulation of RNA molecules in experimental settings. The TEA salt form ensures ease of handling and compatibility with biological assays, making it a valuable tool in RNA-related research endeavors.

CAT: BRP-00675

Molecular Formula: C10H17N2O16P3 (free acid)

Molecular Weight: 514.17 (free acid)

Purity: >98%

Description: Cy3-UTP sodium salt is a modified form of uridine triphosphate (UTP) with a Cyanine 3 (Cy3) fluorescent dye attached to the 5th position of the uracil base. This modification allows for the labeling of RNA molecules during transcription, enabling their visualization in biological assays. The sodium salt addition enhances solubility and stability, making it useful in molecular biology applications such as RNA labeling, fluorescence in situ hybridization (FISH), and real-time RNA detection, aiding research in gene expression and RNA biology.

CAT: BRP-00676

Molecular Formula: C43H56N5O22P3S2 (free acid)

Molecular Weight: 1151.98 (free acid)

Purity: >95%

Description: Fluorescein-12-UTP sodium salt is a modified form of uridine triphosphate (UTP) where a fluorescein molecule is attached to the 5th position of the uracil base. This modification allows for the incorporation of a fluorescent tag into RNA molecules during transcription, enabling their visualization and detection in various biological assays. The addition of a sodium salt enhances the compound's solubility and stability, making it well-suited for applications such as RNA labeling, fluorescence in situ hybridization (FISH), and real-time monitoring of RNA synthesis and degradation processes.

CAT: BRP-00677

Molecular Formula: C39H41N4O22P3 (free acid)

Molecular Weight: 1010.68 (free acid)

Purity: >95%

Description: ATP(αS) sodium salt is a chemical compound wherein the sulfur (S) atom is substituted for oxygen (O) at the α-phosphate position of adenosine triphosphate (ATP). This modification, known as α-thio substitution, alters the chemical properties of ATP, making it resistant to hydrolysis by certain enzymes. The addition of a sodium salt enhances the compound's solubility and stability, making it valuable for biochemical research. ATP(αS) sodium salt is often utilized in studies focusing on ATP-binding proteins, enzyme kinetics, and elucidating cellular signaling pathways.

CAT: BRP-00678

Molecular Formula: C10H16N5O12P3S (free acid)

Molecular Weight: 523.24 (free acid)

Purity: >98%

Appearance: Colorless to light yellow liquid