Comprehensive ASO Libraries for Target Discovery & Validation
We specialize in high-quality antisense oligonucleotide (ASO) library synthesis, offering researchers and biotech companies reliable, scalable, and customizable solutions for drug discovery, gene silencing, functional genomics, and drug target validation. With advanced synthesis platforms, rigorous quality control, and expert bioinformatics support, our service ensures precise sequence design, fast turnaround, and reproducible results for your ASO projects. Utilizing advanced chemically modified oligonucleotides, we enable efficient and specific mRNA targeting to accelerate therapeutic development and mechanistic studies.
Low Yield in ASO Synthesis: Traditional synthesis methods often produce ASOs with low yield and inconsistent quality. Our optimized protocols ensure high-yield production with exceptional purity for every oligonucleotide in your library.
Poor Target Specificity: Ineffective sequence design can lead to off-target effects and reduced knockdown efficiency. We use advanced bioinformatics to design ASOs with superior target specificity and minimal cross-reactivity.
High Screening Costs: Large-scale ASO screening can be expensive and time-consuming. Our high-throughput synthesis capabilities significantly reduce per-sample cost while maintaining consistent quality across the library.
Limited Scalability: Scaling from pilot studies to high-throughput applications is a challenge for many labs. Our platform supports seamless scalability, enabling you to expand your ASO projects without compromising performance.
Lack of Chemical Modification Options: Some suppliers offer limited modification capabilities, restricting ASO stability and efficacy. We provide a full range of backbone and sugar modifications to enhance binding affinity and in vivo performance.
By combining technical expertise with state-of-the-art synthesis platforms, we help you streamline your ASO research and bring your therapeutic or diagnostic projects closer to success.
Target-specific sequence design, off-target analysis, and secondary structure prediction.
Parallel synthesis of hundreds to thousands of oligonucleotides with precise control over length, modifications, and purity.
Wide range of backbone and sugar modifications (e.g., phosphorothioate, 2′-O-Me, LNA) to enhance stability and binding affinity.
HPLC and mass spectrometry analysis, purity reports, and functional validation options.
From small pilot libraries to large-scale screening collections.
Optimized workflows for rapid delivery without compromising quality.
Specify gene(s) or mRNA regions of interest.
Custom ASO sequences with optimal modifications.
High-throughput synthesis with stringent quality control.
Purified, ready-to-use ASO libraries in scalable formats.
Systematic screening to identify druggable mRNA regions, as shown in TNFα mRNA cleavage optimization.
Rapid assessment of gene function in in vitro and in vivo models.
Support for monogenic disorder treatments through precise ASO-mediated gene modulation.
Proven utility in gene functionalization and drug target validation.
An ASO library is a collection of antisense oligonucleotides designed to target multiple gene sequences simultaneously, enabling high-throughput screening for functional genomics, target validation, and therapeutic discovery.
Yes. Our bioinformatics team provides sequence design, off-target analysis, and secondary structure prediction to ensure optimal performance.
Absolutely. We offer multiple chemical modifications—including phosphorothioate, 2′-O-Me, and LNA—to enhance nuclease resistance and improve pharmacokinetics for in vivo applications.
We provide HPLC chromatograms, mass spectrometry results, and purity reports for every ASO in your library.
Unlock the full potential of your genetic research and therapeutic discovery with our custom Antisense Oligonucleotide library synthesis solutions. Whether you need a small-scale pilot set or a high-throughput screening library, we deliver precision-designed, high-purity ASOs tailored to your specific targets—fast, reliable, and ready for action. Partner with us to streamline your workflow, reduce costs, and achieve consistent, reproducible results. Contact us today to request a free consultation or a custom quote, and take the next step toward advancing your ASO-based innovations.
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Global Supplier of High-Quality RNA / DNA Products & Services.
