DLin-KC2-DMA - CAS 1190197-97-7 Catalog number: Model.CurrentData.Catalog

DLin-KC2-DMA is a cationic/ionizable lipid for siRNA delivery. DLin-KC2-DMA was formulated and characterized in SNALP and demonstrated to have in vivo activity at siRNA doses as low as 0.01 mg/kg in rodents and 0.1 mg/kg in nonhuman primates.

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Catalog Number Size Price Stock Quantity
BRH-001 10 mg $298 In stock
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Synonyms
2,2-dilinoleyl-4-dimethylaminoethyl-[1,3]-dioxolane
CAS
1190197-97-7
IUPAC Name
2-[2,2-bis[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine
Molecular Weight
642.09
Molecular Formula
C43H79NO2
Canonical SMILES
CCCCCC=CCC=CCCCCCCCCC1(OCC(O1)CCN(C)C)CCCCCCCCC=CCC=CCCCCC
InChI
InChI=1S/C43H79NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-38-43(45-41-42(46-43)37-40-44(3)4)39-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h13-16,19-22,42H,5-12,17-18,23-41H2,1-4H3/b15-13-,16-14-,21-19-,22-20-
InChIKey
LRFJOIPOPUJUMI-KWXKLSQISA-N
Purity
>98%
Storage
Store at -20°C
Formulation
May be formulated in DMSO
Description
DLin-KC2-DMA is a cationic/ionizable lipid for siRNA delivery. DLin-KC2-DMA was formulated and characterized in SNALP and demonstrated to have in vivo activity at siRNA doses as low as 0.01 mg/kg in rodents and 0.1 mg/kg in nonhuman primates.

Chemical Structure:

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