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Zerlasiran - CAS 2646703-64-0

Catalog number: BRP-02072

Zerlasiran

Zerlasiran, an apolipoprotein A (ApoA) synthesis reducer, is a small interfering RNA (siRNA) therapeutic developed for the treatment of cardiovascular diseases. By specifically targeting and silencing the messenger RNA (mRNA) responsible for the production of atherogenic proteins, zerlasiran aims to reduce the expression of these proteins and thereby mitigate the progression of atherosclerosis and other related conditions.

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.
Catalog
BRP-02072
Synonyms
RNA, (Am-sp-(2'-deoxy-2'-fluoro)U-sp-Am-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-Cm-sp-(2'-deoxy-2'-fluoro)C-sp-Gm), complex with RNA (Cm-Gm-Gm-Um-Am-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)G-Am-Cm-Am-Gm-Am-Gm-Um-Um-sp-Am-sp-Um) 5'-[O-[21-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-9,9-bis[12-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-7-mercapto-7-oxido-2,6,8-trioxa-7-phosphadodec-1-yl]-16-mercapto-16-oxido-7,11,15,17-tetraoxa-16-phosphaheneicos-1-yl] hydroxy phosphate] (1:1)
CAS
2646703-64-0
Molecular Weight
14155.81
Molecular Formula
C443H594N144O277P40S10

Chemical Structure:


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BOC Sciences is a leading provider of DNA and RNA products and services that meet the needs of researchers and pharmaceutical companies worldwide. Its broad product portfolio includes various types of oligonucleotides, DNA/RNA synthesis feedstocks, RNA interference tools, and advanced drug delivery systems, among others. Designed to promote cutting-edge research and innovative therapeutic solutions, at BOC Sciences you are sure to find the right product for you.

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