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5'-O-DMT-2'-deoxy-T-3'-suc-CPG 2000 Å is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating thymidine (T) residues. It features a 5'-O-DMT (dimethoxytrityl) protective group to safeguard the 5' end of the thymidine during synthesis, and a succinyl (Suc) linker that attaches the nucleoside to controlled pore glass (CPG) with a 2000 Å pore size. The larger pore size is ideal for synthesizing longer DNA sequences, allowing for efficient incorporation of thymidine with high loading capacity and stability during the synthesis process.
Chemical Structure:
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