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5'-O-DMT-2'-deoxy-T-3'-suc-CPG 1000 Å is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating thymidine (T) residues. It features a 5'-O-DMT (dimethoxytrityl) protective group to safeguard the 5' end of the thymidine during synthesis, and a succinyl (Suc) linker that attaches the nucleoside to controlled pore glass (CPG) with a 1000 Å pore size. The larger pore size is ideal for synthesizing longer DNA sequences, allowing for efficient incorporation of thymidine with high loading capacity and stability during the synthesis process.
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