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dA-CPG; 1000 Å is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating deoxyadenosine (A) residues. It features a 5'-O-DMT (dimethoxytrityl) protective group, a benzoyl (Bz) protecting group on the adenine base, and a succinyl (Suc) linker that attaches the nucleoside to controlled pore glass (CPG) with a 1000 Å pore size. This configuration is designed for the efficient synthesis of longer DNA sequences, ensuring precise incorporation of deoxyadenosine with stable protection during the synthesis process.
Chemical Structure: