Inquiry Basket
C8-Alkyne-dA CEP
C8-Alkyne-dA phosphoramidite is a specialized phosphoramidite used in the chemical synthesis of oligonucleotides. It features an alkyne group attached to the C8 position of deoxyadenosine, allowing for click chemistry reactions, such as the attachment of various functional groups or labels. This phosphoramidite is used to introduce reactive alkyne moieties into oligonucleotides, facilitating the creation of modified nucleic acids for applications in molecular biology, diagnostics, and the development of therapeutic agents.
* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.
Catalog
BRP-02198
Synonyms
C8-Alkyne-dA Phosphoramidite; Propanamide, N-[7-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-5-(1,7-octadiyn-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methyl-; N-[7-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-5-(1,7-octadiyn-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methylpropanamide; 7-Deaza-C8-Alkyne-2'-deoxy-adenosine 3'-CE-Phosphoramidite
CAS
1002322-75-9
IUPAC Name
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-isobutyramido-5-(octa-1,7-diyn-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
Molecular Weight
927.10
Molecular Formula
C53H63N6O7P
Canonical SMILES
N#CCCOP(OC1CC(OC1COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C=C(C#CCCCCC#C)C=6C(=NC=NC65)NC(=O)C(C)C)N(C(C)C)C(C)C
InChI
InChI=1S/C53H63N6O7P/c1-10-11-12-13-14-16-20-40-34-58(51-49(40)50(55-36-56-51)57-52(60)37(2)3)48-33-46(66-67(64-32-19-31-54)59(38(4)5)39(6)7)47(65-48)35-63-53(41-21-17-15-18-22-41,42-23-27-44(61-8)28-24-42)43-25-29-45(62-9)30-26-43/h1,15,17-18,21-30,34,36-39,46-48H,11-14,19,32-33,35H2,2-9H3,(H,55,56,57,60)/t46-,47+,48+,67?/m0/s1
InChIKey
DMVMVASVMSMXMZ-MVAJTOPMSA-N
Boiling Point
955.7±65.0°C at 760 mmHg
Purity
≥95%
Appearance
White to Off-white Foam
Storage
Store at -20 °C
Chemical Structure:
