Name: C8-Alkyne-dA CEP
Brand: BOC Sciences
Rating: 5 (1 reviews)

C8-Alkyne-dA CEP

C8-Alkyne-dA phosphoramidite is a specialized phosphoramidite used in the chemical synthesis of oligonucleotides. It features an alkyne group attached to the C8 position of deoxyadenosine, allowing for click chemistry reactions, such as the attachment of various functional groups or labels. This phosphoramidite is used to introduce reactive alkyne moieties into oligonucleotides, facilitating the creation of modified nucleic acids for applications in molecular biology, diagnostics, and the development of therapeutic agents.

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Catalog

BRP-02198

Synonyms

C8-Alkyne-dA Phosphoramidite; Propanamide, N-[7-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-5-(1,7-octadiyn-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methyl-; N-[7-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-5-(1,7-octadiyn-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-methylpropanamide; 7-Deaza-C8-Alkyne-2'-deoxy-adenosine 3'-CE-Phosphoramidite

CAS

1002322-75-9

IUPAC Name

(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-isobutyramido-5-(octa-1,7-diyn-1-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

Molecular Weight

927.10

Molecular Formula

C53H63N6O7P

Canonical SMILES

N#CCCOP(OC1CC(OC1COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C=C(C#CCCCCC#C)C=6C(=NC=NC65)NC(=O)C(C)C)N(C(C)C)C(C)C

InChI

InChI=1S/C53H63N6O7P/c1-10-11-12-13-14-16-20-40-34-58(51-49(40)50(55-36-56-51)57-52(60)37(2)3)48-33-46(66-67(64-32-19-31-54)59(38(4)5)39(6)7)47(65-48)35-63-53(41-21-17-15-18-22-41,42-23-27-44(61-8)28-24-42)43-25-29-45(62-9)30-26-43/h1,15,17-18,21-30,34,36-39,46-48H,11-14,19,32-33,35H2,2-9H3,(H,55,56,57,60)/t46-,47+,48+,67?/m0/s1

InChIKey

DMVMVASVMSMXMZ-MVAJTOPMSA-N

Boiling Point

955.7±65.0°C at 760 mmHg

Purity

≥95%

Appearance

White to Off-white Foam

Storage

Store at -20 °C

Chemical Structure:

Our Products

BOC Sciences is a leading provider of DNA and RNA products and services that meet the needs of researchers and pharmaceutical companies worldwide. Its broad product portfolio includes various types of oligonucleotides, DNA/RNA synthesis feedstocks, RNA interference tools, and advanced drug delivery systems, among others. Designed to promote cutting-edge research and innovative therapeutic solutions, at BOC Sciences you are sure to find the right product for you.

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