5'-DMT-T-3'-Q Linker-CPG; 1000 Å is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating thymidine (T) residues. It features a 5'-DMT (dimethoxytrityl) protective group, a thymidine base, and a 3'-Q (quencher) linker attached to controlled pore glass (CPG) with a 1000 Å pore size. The 3'-Q linker typically includes a quencher dye or group, used for fluorescence-based assays or to create fluorescently quenched probes. The 5'-DMT group protects the 5' end during synthesis, while the large pore size of the CPG allows for high loading capacity and efficient oligonucleotide synthesis.
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