Inquiry Basket
3'-Thiol Modifier C6 SS Glyc CPG; 1000 Å
3'-Thiol Modifier C6 SS Glyc CPG; 1000 Å is a reagent used in the solid-phase synthesis of oligonucleotides to incorporate a protected thiol group at the 3' end. It features a 6-carbon spacer (C6) with a disulfide bond (SS) linked to a glycyl group (Glyc), attached to controlled pore glass (CPG) with a 1000 Å pore size. This setup allows for the introduction of a thiol group, which can be used for further conjugation or cross-linking reactions, while the disulfide bond can be cleaved to reveal the free thiol group after synthesis.
* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.
Catalog
BRP-02246
Synonyms
3'-Thiol Modifier C6 S-S Glyc CPG
Appearance
White to off-white powder
Storage
Store at -20 °C
Shipping
Room temperature.
Deprotection Conditions
Deprotect the oligo in NH4OH for 2h at 65°C if using fast deprotecting amidites, or 5h at 65°C if using standard amidites. This will remove only the base protecting groups.
Chemical Structure:
