Name: 3'-DMT-T-Suc-CPG; 1000 Å
Brand: BOC Sciences
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3'-DMT-T-Suc-CPG; 1000 Å

3'-DMT-T-Suc-CPG; 1000 Å is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating thymine residues. It features a 3'-DMT protective group on the thymine base and a succinyl linker that connects the nucleoside to controlled pore glass (CPG) with a pore size of 1000 Å. This setup is ideal for synthesizing longer DNA sequences with precise thymine incorporation and facilitates efficient deprotection and release of the oligonucleotide from the solid support.

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Catalog

BRP-02250

Synonyms

3'-O-(4,4'-Dimethoxytrityl)-2'-deoxythymine-5'-Suc-CPG 1000 Å; 2'-deoxy-3'-O-DMT-thymine-5'-Suc-CPG 1000 Å; 2'-deoxy-3'-O-dimethoxytritylthymine-5'-Suc-CPG 1000 Å

Appearance

White powder

Storage

Store at 2-8 °C

Shipping

Room temperature.

Cleavage Conditions

Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.

Deprotection Conditions

When using fast deprotecting amidites (e.g., C-Ac; G-DMF; G-PAC), please use concentrated ammonia for 1h or AMA for 30 min at 60°C. When using standard amidites (e.g., C-Bz; G-iBu), please use concentrated ammonia for 5h at 60°C.

Chemical Structure:

Our Products

BOC Sciences is a leading provider of DNA and RNA products and services that meet the needs of researchers and pharmaceutical companies worldwide. Its broad product portfolio includes various types of oligonucleotides, DNA/RNA synthesis feedstocks, RNA interference tools, and advanced drug delivery systems, among others. Designed to promote cutting-edge research and innovative therapeutic solutions, at BOC Sciences you are sure to find the right product for you.

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