Nucleosides - RNA / BOC Sciences

3'-O-TBDMS-2'-O-Me-rA(Bz)

Description: 3'-O-TBDMS-2'-O-Me-rA(Bz) is a modified ribonucleoside where a tert-butyldimethylsilyl (TBDMS) group is attached to the 3'-hydroxyl position, and a methyl group is attached to the 2'-hydroxyl position of adenosine. Additionally, the adenine base is protected by a benzoyl (Bz) group. This modification enhances the stability and reactivity of the ribonucleoside, making it useful for the synthesis of RNA oligonucleotides, particularly in solid-phase synthesis methodologies.

CAT: BRP-00722

CAS: 454424-09-0

MF: C24H33N5O5Si

MF: 499.64

Purity: ≥98% by HPLC

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Storage: Store at 2-8 °C

Density: 1.28±0.1 g/cm3

InChIKey: ROHHXNDVYNHGRQ-DYVMYPEFSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1OC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO

IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C24H33N5O5Si/c1-24(2,3)35(5,6)34-18-16(12-30)33-23(19(18)32-4)29-14-27-17-20(25-13-26-21(17)29)28-22(31)15-10-8-7-9-11-15/h7-11,13-14,16,18-19,23,30H,12H2,1-6H3,(H,25,26,28,31)/t16-,18-,19-,23-/m1/s1

Synonyms: Adenosine, N-benzoyl-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyl-; N-Benzoyl-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyladenosine; N-(9-((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

5'-O-DMT-N4-Ac-2'-O-(2-methoxyethyl)cytidine

Description: 5'-O-DMT-N4-Ac-2'-O-(2-methoxyethyl)cytidine is a modified cytidine nucleoside used in oligonucleotide synthesis. It features a cytidine base with an N4-acetyl modification and a 2'-O-(2-methoxyethyl) group attached to the ribose sugar moiety. This modification enhances the stability and specificity of the resulting oligonucleotides, making them valuable tools in various molecular biology applications.

CAT: BRP-00744

CAS: 1345716-47-3

MF: C35H39N3O9

MF: 645.71

Purity: >98%

Appearance: White to light yellow powder

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Density: 1.27±0.1 g/cm3

InChIKey: RLHWWSNMWZITIE-WXQJYUTRSA-N

CanonicalSMILES: O=C1N=C(C=CN1C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(O)C2OCCOC)NC(=O)C

IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

InChI: InChI=1S/C35H39N3O9/c1-23(39)36-30-18-19-38(34(41)37-30)33-32(45-21-20-42-2)31(40)29(47-33)22-46-35(24-8-6-5-7-9-24,25-10-14-27(43-3)15-11-25)26-12-16-28(44-4)17-13-26/h5-19,29,31-33,40H,20-22H2,1-4H3,(H,36,37,39,41)/t29-,31-,32-,33-/m1/s1

Synonyms: Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)cytidine

5'-O-DMT-N4-Ac-5-Me-2'-O-(2-methoxyethyl)cytidine

Description: 5'-O-DMT-N4-Ac-5-Me-2'-O-(2-methoxyethyl)cytidine is a modified cytidine nucleoside used in oligonucleotide synthesis. This modification further alters the properties of the oligonucleotides, potentially influencing their stability and interactions with target molecules. These modified nucleosides find applications in research areas such as RNA therapeutics, antisense technology, and gene expression studies, where precise control over oligonucleotide properties is essential.

CAT: BRP-00745

MF: C36H41N3O9

MF: 659.74

Purity: >98%

Appearance: White to light yellow powder

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Storage: Store at 2-8 °C, Keep in a dark and dry place

InChIKey: MPYIKKBQDQPMLE-UKNNOAMWSA-N

IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

InChI: InChI=1S/C36H41N3O9/c1-23-21-39(35(42)38-33(23)37-24(2)40)34-32(46-20-19-43-3)31(41)30(48-34)22-47-36(25-9-7-6-8-10-25,26-11-15-28(44-4)16-12-26)27-13-17-29(45-5)18-14-27/h6-18,21,30-32,34,41H,19-20,22H2,1-5H3,(H,37,38,40,42)/t30-,31-,32-,34-/m1/s1

Synonyms: N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methylcytidine; N4-Acetyl-2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine; 5'-O-DMTr-2'-O-MOE-5-Me-C(Ac); N4-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-5-methyl-cytidine

5'-O-DMTr-2'-O-TBS-rU-3'-O-succinate, TEA salt

Description: 5'-O-DMTr-2'-O-TBS-rU-3'-O-succinate, TEA salt, a modified uridine nucleoside derivative, serves as a building block in RNA synthesis. The dimethoxytrityl (DMTr) and tert-butyldimethylsilyl (TBS) groups protect the 5' and 2' hydroxyl groups, respectively, enabling controlled polymerization. The succinate moiety at the 3' position facilitates conjugation to other molecules, making it valuable for site-specific labeling and conjugation studies in RNA biochemistry.

CAT: BRP-00746

MF: C40H48N2O11Si (free acid)

MF: 760.90 (free acid)

Purity: >98%

Appearance: White to yellow powder

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Storage: Store at -20 °C, in tightly closed containers, protected from humidity

IUPAC Name: 4-[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-uridine-3'-O-succinate, triethylamine salt; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-(hydrogen butanedioate) triethylamine salt; Triethylamine 4-(((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)oxy)-4-oxobutanoate; DMT-2'-O-TBDMS-Ur-3'-succinate, TEA salt; 5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-uridine-3'-O-succinate, triethylamine salt

Related CAS: 119702-12-4 (free base)

N6-Bz-5'-O-DMTr-2'-O-TBS-rA-3'-O-succinate, TEA salt

Description: N6-Bz-5'-O-DMTr-2'-O-TBS-rA-3'-O-succinate, TEA salt, an adenine derivative, is crucial for RNA synthesis, offering site-specific modifications. The N6 position of the adenine base is protected with a benzoyl (Bz) group, ensuring controlled reactivity during synthesis. The DMTr and TBS groups protect the 5' and 2' hydroxyl groups, respectively, while the succinate moiety facilitates conjugation reactions, making it suitable for site-specific labeling and conjugation studies in RNA research.

CAT: BRP-00747

MF: C48H53N5O10Si (free acid)

MF: 888.05 (free acid)

Purity: >98%

Appearance: White to yellow powder

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Storage: Store at -20 °C, in tightly closed containers, protected from humidity

IUPAC Name: 4-[(2R,3R,4R,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxyoxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: 4-(((2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid, triethylamine salt; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-(hydrogen butanedioate), triethylamine salt; N6-Bz-DMT-2'-O-TBDMS-Ar-3'-succinate, TEA salt; N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-adenosine-3'-O-succinate, triethylamine salt

Related CAS: 131316-88-6 (free base)

N2-iBu-5'-O-DMTr-2'-O-TBS-rG-3'-O-succinate, TEA salt

Description: N2-iBu-5'-O-DMTr-2'-O-TBS-rG-3'-O-succinate, TEA salt, a guanosine derivative, plays a vital role in RNA synthesis and modification. The isobutyl (iBu) group at the N2 position of the guanine base provides stability and selective reactivity during oligonucleotide assembly. The DMTr and TBS groups protect the 5' and 2' hydroxyl groups, respectively, while the succinate moiety offers a handle for conjugation reactions, enabling versatile applications in RNA research.

CAT: BRP-00748

MF: C45H55N5O11Si (free acid)

MF: 870.04 (free acid)

Purity: >98%

Appearance: White to yellow powder

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Storage: Store at -20 °C, in tightly closed containers, protected from humidity

IUPAC Name: 4-[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: 4-(((2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-isobutyramido-6-oxo-3,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid, triethylamine salt; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-, 3'-(hydrogen butanedioate), triethylamine salt; N2-iBu-DMT-2'-O-TBDMS-Gr-3'-succinate, TEA salt; N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-guanosine-3'-O-succinate, triethylamine salt

Related CAS: 131289-17-3 (free base)

N4-Ac-5'-O-DMTr-5-Me-2'-O-TBS-rC-3'-O-succinate, TEA salt

Description: N4-Ac-5'-O-DMTr-5-Me-2'-O-TBS-rC-3'-O-succinate, TEA salt, a cytidine derivative, is essential for RNA synthesis, offering precise modifications. The acetyl (Ac) group at the N4 position of the cytosine base provides stability and specific reactivity during oligonucleotide synthesis. The presence of a 5-methyl modification enhances stability and base pairing specificity. The DMTr and TBS groups protect the 5' and 2' hydroxyl groups, respectively, while the succinate moiety facilitates conjugation reactions, enabling tailored functionalization of RNA molecules.

CAT: BRP-00749

MF: C43H53N3O11Si (free acid)

MF: 815.99 (free acid)

Purity: >98%

Appearance: White to yellow powder

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IUPAC Name: 4-(((2R,3R,4R,5R)-5-(4-acetamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-(hydrogen butanedioate), 5-methylcytidine, triethylamine salt

N4-Bz-5'-O-DMTr-5-Me-2'-O-TBS-rC-3'-O-succinate, TEA salt

Description: N4-Bz-5'-O-DMTr-5-Me-2'-O-TBS-rC-3'-O-succinate, TEA salt, a cytidine derivative, features a benzoyl (Bz) group at the N4 position of the cytosine base, providing stability and controlled reactivity. The 5-methyl modification enhances stability and base pairing specificity. The DMTr and TBS groups protect the 5' and 2' hydroxyl groups, respectively, while the succinate moiety offers a handle for conjugation, facilitating tailored functionalization of RNA molecules.

CAT: BRP-00750

MF: C48H55N3O11Si (free acid)

MF: 878.06 (free acid)

Purity: >98%

Appearance: White to yellow powder

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IUPAC Name: 4-(((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-(hydrogen butanedioate), 5-methylcytidine, triethylamine salt

N4-Ac-5'-O-DMTr-2'-O-TBS-rC-3'-O-succinate, TEA salt

Description: N4-Ac-5'-O-DMTr-2'-O-TBS-rC-3'-O-succinate, TEA salt, a cytidine derivative, is a versatile building block in RNA synthesis, offering precise modifications. The acetyl (Ac) group at the N4 position of the cytosine base provides stability and specific reactivity during oligonucleotide assembly. The DMTr and TBS groups protect the 5' and 2' hydroxyl groups, respectively, while the succinate moiety facilitates conjugation reactions, enabling tailored functionalization of RNA molecules.

CAT: BRP-00751

MF: C42H51N3O11Si (free acid)

MF: 801.33 (free acid)

Purity: >98%

Appearance: White to yellow powder

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IUPAC Name: 4-[(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxyoxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-(hydrogen butanedioate) triethylamine salt; 4-(((2R,3R,4R,5R)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid triethylamine salt

Related CAS: 2940874-25-7 (free base)

5'-O-DMTr-5-Me-2'-O-TBS-rU-3'-O-succinate, TEA salt

Description: 5'-O-DMTr-5-Me-2'-O-TBS-rU-3'-O-succinate, TEA salt, a modified uridine nucleoside derivative, is crucial for RNA synthesis and modification. The presence of a 5-methyl modification enhances stability and base pairing specificity. The DMTr and TBS groups protect the 5' and 2' hydroxyl groups, respectively, while the succinate moiety facilitates conjugation reactions, making it suitable for site-specific labeling and conjugation studies in RNA biochemistry.

CAT: BRP-00752

MF: C41H50N2O11Si (free acid)

MF: 774.94 (free acid)

Purity: >98%

Appearance: White to yellow powder

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IUPAC Name: 4-(((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-5-methyluridine-3'-O-succinate, triethylamine salt; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-methyl-, 3'-(hydrogen butanedioate), triethylamine salt

Related CAS: 159639-79-9 (free base)

N4-Bz-5'-O-DMTr-2'-O-TBS-rC-3'-O-succinate, TEA salt

Description: N4-Bz-5'-O-DMTr-2'-O-TBS-rC-3'-O-succinate, TEA salt is a cytidine derivative used in RNA synthesis, featuring a benzoyl (Bz) group at the N4 position of the cytosine base, which provides stability and controlled reactivity during oligonucleotide assembly. The 5' and 2' hydroxyl groups are protected by dimethoxytrityl (DMTr) and tert-butyldimethylsilyl (TBS) groups, respectively. Additionally, the succinate moiety at the 3' end facilitates conjugation reactions, making it suitable for site-specific labeling and conjugation studies in RNA research. The TEA (triethylammonium) salt form enhances solubility and stability for practical use in biochemical applications.

CAT: BRP-00753

MF: C47H53N3O11Si (free acid)

MF: 864.04 (free acid)

Purity: >98%

Appearance: White to yellow powder

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IUPAC Name: 4-[(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxyoxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-(hydrogen butanedioate) triethylamine salt; 4-(((2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid triethylamine salt

Related CAS: 131289-16-2 (free base)

2-Amino-6-chloro-9-(3'-O-methyl-beta-D-ribofuranosyl)-9H-purine

Description: Used for further modified purine nucleoside synthesis.

CAT: BRP-00759

MF: C11H14ClN5O4

MF: 315.71

Purity: ≥98%

Appearance: White or off-white solid

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Storage: Store at 2-8 °C

InChIKey: PMVUXOVFDRGLHZ-KQYNXXCUSA-N

CanonicalSMILES: COC1C(OC(C1O)N2C=NC3=C2N=C(N=C3Cl)N)CO

IUPAC Name: (2R,3R,4S,5R)-2-(2-amino-6-chloropurin-9-yl)-5-(hydroxymethyl)-4-methoxyoxolan-3-ol

InChI: InChI=1S/C11H14ClN5O4/c1-20-7-4(2-18)21-10(6(7)19)17-3-14-5-8(12)15-11(13)16-9(5)17/h3-4,6-7,10,18-19H,2H2,1H3,(H2,13,15,16)/t4-,6-,7-,10-/m1/s1

Synonyms: 3'-O-methyl-2-amino-6-chloro-6-deamino-adenosine; (2R,3R,4S,5R)-2-(2-amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol

2'-O-Propargyl-5-methyl uridine

Description: It is used for the synthesis of 2'-modified nucleoside phosphoramidites and corresponding modified RNA oligomers.

CAT: BRP-00760

CAS: 860640-50-2

MF: C13H16N2O6

MF: 296.28

Purity: ≥97%

Appearance: White or off-white solid

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Storage: Store at 2-8 °C

Density: 1.46±0.1 g/cm3

InChIKey: BSRONJSLOYHEHY-DNRKLUKYSA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)OCC#C

IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-prop-2-ynoxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C13H16N2O6/c1-3-4-20-10-9(17)8(6-16)21-12(10)15-5-7(2)11(18)14-13(15)19/h1,5,8-10,12,16-17H,4,6H2,2H3,(H,14,18,19)/t8-,9-,10-,12-/m1/s1

Synonyms: 2'-O-Propargyl-5-methyluridine; 5-Methyl-2'-O-2-propyn-1-yluridine; Uridine, 5-methyl-2'-O-2-propynyl-; Uridine, 5-methyl-2'-O-2-propyn-1-yl-; 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-5-methyluridine

Description: It is used for the synthesis of 2'-modified nucleoside phosphoramidites and corresponding modified RNA oligomers. This modified nucleoside exhibits the exceptional ability to integrate into RNA molecules, thereby facilitating the exploration of RNA's intricate structure and functionality.

CAT: BRP-00761

CAS: 860640-56-8

MF: C34H34N2O8

MF: 598.64

Purity: ≥98%

Appearance: White or off-white solid

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Storage: Store at 2-8 °C

Density: 1.34±0.1 g/cm3

InChIKey: OEAZBXNAASQUGJ-PBAMLIMUSA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OCC#C

IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-prop-2-ynoxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C34H34N2O8/c1-5-19-42-30-29(37)28(44-32(30)36-20-22(2)31(38)35-33(36)39)21-43-34(23-9-7-6-8-10-23,24-11-15-26(40-3)16-12-24)25-13-17-27(41-4)18-14-25/h1,6-18,20,28-30,32,37H,19,21H2,2-4H3,(H,35,38,39)/t28-,29-,30-,32-/m1/s1

Synonyms: 5-O-(4,4'-dimethoxytrityl)-1-deoxy-2-O-prop-2-ynyl-1-thymin-1-yl-beta-D-ribo-pentofuranose; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-methyl-2'-O-2-propyn-1-yluridine; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-methyl-2'-O-2-propynyl-; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

2'-O-(2-Methoxyethyl)-5-methylcytidine hydrochloride

Description: It is used for oligonucleotide synthesis and biotechnological studies.

CAT: BRP-00767

MF: C13H22ClN3O6

MF: 351.78

Purity: ≥97% by HPLC

Appearance: White or off-white solid

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Storage: Store at 2-8 °C

InChIKey: YPFHLLIYUOCCOJ-YBZJUNAKSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)OCCOC.Cl

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidin-2-one;hydrochloride

InChI: InChI=1S/C13H21N3O6.ClH/c1-7-5-16(13(19)15-11(7)14)12-10(21-4-3-20-2)9(18)8(6-17)22-12;/h5,8-10,12,17-18H,3-4,6H2,1-2H3,(H2,14,15,19);1H/t8-,9-,10-,12-;/m1./s1

Synonyms: 5-Methyl-2'-methoxyethoxycytosine hydrochloride; Cytidine, 2'-O-(2-Methoxyethyl)-5-Methyl-, hydrochloride (1:1); 2'-O-MOE-5-Me-rC hydrochloride; 2'-MOE-5-Methycytidine hydrochloride; 5-Methyl-2'-O-methoxyethyl-cytidine hydrochloride

Related CAS: 244105-55-3 (free base)

5'-O-DMT-5-Hydroxyethyl-dU

Description: 5'-O-DMT-5-Hydroxyethyl-dU is a modified form of deoxyuridine (dU) featuring a 5'-O-DMT (dimethoxytrityl) protecting group and a hydroxyethyl moiety at the 5 position of the uracil base. This modification introduces hydrophilicity and alters the base pairing properties of the nucleotide, making it useful in various biochemical applications, including DNA synthesis and structural studies.

CAT: BRP-00768

CAS: 1411974-64-5

MF: C32H34N2O8

MF: 574.63

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Density: 1.297±0.06 g/cm3

InChIKey: KCPHUOHHZQNELQ-ZGIBFIJWSA-N

CanonicalSMILES: O=C1NC(=O)N(C=C1CCO)C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(O)C2

IUPAC Name: 1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-(2-hydroxyethyl)pyrimidine-2,4(1H,3H)-dione

InChI: InChI=1S/C32H34N2O8/c1-39-25-12-8-23(9-13-25)32(22-6-4-3-5-7-22,24-10-14-26(40-2)15-11-24)41-20-28-27(36)18-29(42-28)34-19-21(16-17-35)30(37)33-31(34)38/h3-15,19,27-29,35-36H,16-18,20H2,1-2H3,(H,33,37,38)/t27-,28+,29+/m0/s1

Synonyms: 5'-O-DMT-5-Hydroxyethyl-2'-deoxyuridine; 5'-O-DMT-2'-Deoxy-5-(hydroxyethyl)uridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-(2-hydroxyethyl)uridine

5'-O-DMT-2'-O-TBDMS-N2-ibu-L-rG

Description: 5'-O-DMT-2'-O-TBDMS-N2-ibu-L-rG is a guanosine derivative used in RNA synthesis, with a 5'-O-DMT protecting group, a TBDMS (tert-butyldimethylsilyl) group at the 2' position, and an N2-isobutyryl-L modifier at the guanine base. This modification enhances stability and controlled reactivity during oligonucleotide assembly, making it suitable for RNA research and therapeutic development.

CAT: BRP-00769

CAS: 679809-77-9

MF: C41H51N5O8Si

MF: 769.97

Purity: ≥97% by HPLC

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Density: 1.25±0.1 g/cm3

InChIKey: JMCNKJFOIJGYRG-XECBKSLKSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)O[Si](C)(C)C(C)(C)C

IUPAC Name: N-[9-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C41H51N5O8Si/c1-25(2)36(48)44-39-43-35-32(37(49)45-39)42-24-46(35)38-34(54-55(8,9)40(3,4)5)33(47)31(53-38)23-52-41(26-13-11-10-12-14-26,27-15-19-29(50-6)20-16-27)28-17-21-30(51-7)22-18-28/h10-22,24-25,31,33-34,38,47H,23H2,1-9H3,(H2,43,44,45,48,49)/t31-,33-,34-,38-/m0/s1

Synonyms: 5'-O-DMT-2'-O-(tertbutyldimethylsilyl)-N2-isobutyryl-L-Guanosine; N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropanamide

N6-Benzoyl-2',3'-di-O-acetyladenosine

Description: N6-Benzoyl-2’,3’-di-O-acetyladenosine is a modified form of adenosine featuring a benzoyl group at the N6 position and di-O-acetyl groups at the 2' and 3' positions of the ribose sugar. These modifications provide stability and alter the chemical properties of adenosine, making it useful in various biochemical applications, including RNA synthesis and modification studies.

CAT: BRP-00770

CAS: 69293-36-3

MF: C21H21N5O7

MF: 455.43

Purity: ≥95%

Appearance: White to off-white powder

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Storage: Store at 2-8 °C

Density: 1.55±0.1 g/cm3

InChIKey: FGYJKVXTRQIWTE-VGKBRBPRSA-N

CanonicalSMILES: CC(=O)OC1C(OC(C1OC(=O)C)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO

IUPAC Name: [(2R,3R,4R,5R)-4-acetyloxy-5-(6-benzamidopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] acetate

InChI: InChI=1S/C21H21N5O7/c1-11(28)31-16-14(8-27)33-21(17(16)32-12(2)29)26-10-24-15-18(22-9-23-19(15)26)25-20(30)13-6-4-3-5-7-13/h3-7,9-10,14,16-17,21,27H,8H2,1-2H3,(H,22,23,25,30)/t14-,16-,17-,21-/m1/s1

Synonyms: Adenosine, N-benzoyl-, 2',3'-diacetate; 2',3'-di-O-Acetyl-N6-Benzoyl-Adenosine; N6-Bz-2',3'-Acetyl-Adenosine; N6-benzoyl-2',3'-Acetyl-Adenosine; (2R,3R,4R,5R)-2-(6-benzamido-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate; 2',3'-diAc-A(Bz); N6-benzoyl-2',3'-diacetyl-adenosine

(E)-N'-(1-Benzyl-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide

Description: (E)-N'-(1-Benzyl-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide is a chemical compound used in organic synthesis and medicinal chemistry. It is often utilized as a precursor or intermediate in the synthesis of nucleoside analogs or other bioactive compounds.

CAT: BRP-00795

MF: C20H24N6O5

MF: 428.44

Purity: 98%

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InChIKey: ALGXQQKQSPSJBB-DJWODFLFSA-N

InChI: InChI=1S/C20H24N6O5/c1-24(2)10-22-20-23-17-14(18(30)25(20)8-12-6-4-3-5-7-12)21-11-26(17)19-16(29)15(28)13(9-27)31-19/h3-7,10-11,13,15-16,19,27-29H,8-9H2,1-2H3/b22-10+/t13-,15-,16-,19-/m1/s1

5,8-Dihydro-N,N,5-trimethyl-8-β-D-ribofuranosylpyrrolo[2',3':4,5]pyrrolo[2,3-d]pyrimidin-4-amine

Description: 5,8-Dihydro-N,N,5-trimethyl-8-β-D-ribofuranosylpyrrolo[2',3':4,5]pyrrolo[2,3-d]pyrimidin-4-amine is a chemical compound with potential biological activity. It is often studied for its potential pharmacological properties or as a building block in medicinal chemistry for the synthesis of nucleoside analogs.

CAT: BRP-00796

CAS: 2180983-51-9

MF: C16H21N5O4

MF: 347.37

Purity: 98%

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Density: 1.62±0.1 g/cm3

Boiling Point: 588.6±50.0 °C at 760 mmHg

InChIKey: GIPKNLNHAZHJMS-RVXWVPLUSA-N

CanonicalSMILES: CN1C=CC2=C1C3=C(N2C4C(C(C(O4)CO)O)O)N=CN=C3N(C)C

IUPAC Name: (2R,3R,4S,5R)-2-[12-(dimethylamino)-3-methyl-3,7,9,11-tetrazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),4,9,11-pentaen-7-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C16H21N5O4/c1-19(2)14-10-11-8(4-5-20(11)3)21(15(10)18-7-17-14)16-13(24)12(23)9(6-22)25-16/h4-5,7,9,12-13,16,22-24H,6H2,1-3H3/t9-,12-,13-,16-/m1/s1

Synonyms: Pyrrolo[2',3':4,5]pyrrolo[2,3-d]pyrimidin-4-amine, 5,8-dihydro-N,N,5-trimethyl-8-β-D-ribofuranosyl-; (2R,3R,4S,5R)-2-(4-(Dimethylamino)-5-methylpyrrolo[2',3':4,5]pyrrolo[2,3-d]pyrimidin-8(5H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol