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2'-Modified Phosphoramidites
(529/529) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(201/201) 5'-Modified Phosphoramidites
(30/30) Arabino Phosphoramidites
(23/23) Base Protected Phosphoramidites (418/418) Dye Phosphoramidites
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(97/97) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
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(529/529) 2'-Phosphoramidites
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(201/201) 5'-Modified Phosphoramidites
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(53/53) Label Phosphoramidites
(82/82) Linker Phosphoramidites
(85/85) Other Phosphoramidites
(97/97) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
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DMTr-2'-O-4'-C-ethylene-rA(Bz)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-4'-C-ethylene-rA(Bz)-3'-CE-Phosphoramidite, used in oligonucleotide synthesis, contains an ethylene linker at the 2'-O and 4'-C positions of adenosine (rA), with benzoyl (Bz) protection on the adenine amino group. The cyanoethyl (CE) group at the 3'-end facilitates efficient coupling reactions during solid-phase synthesis. It is employed in the construction of RNA sequences with augmented stability and binding affinity, suitable for various research applications including RNA-targeted therapy and gene expression modulation.
CAT: BRP-00600
CAS: 287737-45-5
Molecular Formula: C49H54N7O8P
Molecular Weight: 899.99
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: IUGJZRODLODQAN-QLRWGQFGSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C2C(OC1(CCO2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)N6C=NC7=C(N=CN=C76)NC(=O)C8=CC=CC=C8
IUPAC Name: N-[9-[(1R,5R,7R,8S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-8-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,6-dioxabicyclo[3.2.1]octan-7-yl]purin-6-yl]benzamide
InChI: InChI=1S/C49H54N7O8P/c1-33(2)56(34(3)4)65(62-28-13-27-50)64-43-42-47(55-32-53-41-44(51-31-52-45(41)55)54-46(57)35-14-9-7-10-15-35)63-48(43,26-29-60-42)30-61-49(36-16-11-8-12-17-36,37-18-22-39(58-5)23-19-37)38-20-24-40(59-6)25-21-38/h7-12,14-25,31-34,42-43,47H,13,26,28-30H2,1-6H3,(H,51,52,54,57)/t42-,43+,47-,48-,65?/m1/s1
Synonyms: Benzamide, N-[9-[2,6-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5-deoxy-α-L-lyxo-hexofuranosyl]-9H-purin-6-yl]-; ENA-A(bz) Phosphoramidite; N-[9-[2,6-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5-deoxy-α-L-lyxo-hexofuranosyl]-9H-purin-6-yl]benzamide
DMTr-2'-O-4'-C-ethylene-rG(iBu)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-4'-C-ethylene-rG(iBu)-3'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, features an ethylene linker at the 2'-O and 4'-C positions of guanosine (rG), with isobutyryl (iBu) protection on the guanine amino group. The cyanoethyl (CE) group at the 3'-end facilitates efficient coupling reactions during solid-phase synthesis. This modified nucleotide is valuable for generating RNA sequences with enhanced stability and binding affinity, suitable for applications such as RNA interference (RNAi) and RNA therapeutics.
CAT: BRP-00601
CAS: 287737-58-0
Molecular Formula: C46H56N7O9P
Molecular Weight: 881.97
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: VXCXNHPZXAIEDO-DNUXVXCXSA-N
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C4C(C(O3)(CCO4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(1R,5R,7R,8S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-8-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,6-dioxabicyclo[3.2.1]octan-7-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C46H56N7O9P/c1-29(2)41(54)50-44-49-40-37(42(55)51-44)48-28-52(40)43-38-39(62-63(60-25-12-24-47)53(30(3)4)31(5)6)45(61-43,23-26-58-38)27-59-46(32-13-10-9-11-14-32,33-15-19-35(56-7)20-16-33)34-17-21-36(57-8)22-18-34/h9-11,13-22,28-31,38-39,43H,12,23,25-27H2,1-8H3,(H2,49,50,51,54,55)/t38-,39+,43-,45-,63?/m1/s1
Synonyms: ENA-G(iBu) Phosphoramidite; N-[9-[2,6-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5-deoxy-α-L-lyxo-hexofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropanamide; (1R,5R,7R,8S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-2,6-dioxabicyclo[3.2.1]octan-8-yl (2-cyanoethyl) diisopropylphosphoramidite
DMTr-2'-O-C22-rA(Bz)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-C22-rA(Bz)-3'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, contains a DMTr protecting group at the 5'-position and a cyanoethyl (CE) group at the 3'-end. The nucleoside unit is adenosine (rA), modified with a C22 linker at the 2'-O position and benzoyl (Bz) protection on the adenine amino group. It is employed in the synthesis of RNA sequences with enhanced stability and binding affinity, suitable for various research applications including RNA-based therapy and gene expression modulation.
CAT: BRP-00603
CAS: 2923115-67-5
Molecular Formula: C69H96N7O8P
Molecular Weight: 1182.54
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: BCBFIURHCBIJCZ-GOQGTMNZSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=NC=NC32)NC(=O)C=4C=CC=CC4)C1OCCCCCCCCCCCCCCCCCCCCCC)COC(C=5C=CC=CC5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(docosyloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C69H96N7O8P/c1-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-33-48-80-64-63(84-85(82-49-34-47-70)76(53(2)3)54(4)5)61(83-68(64)75-52-73-62-65(71-51-72-66(62)75)74-67(77)55-35-29-27-30-36-55)50-81-69(56-37-31-28-32-38-56,57-39-43-59(78-6)44-40-57)58-41-45-60(79-7)46-42-58/h27-32,35-46,51-54,61,63-64,68H,8-26,33-34,48-50H2,1-7H3,(H,71,72,74,77)/t61-,63-,64-,68-,85?/m1/s1
-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite.gif)
5'-O-DMT-2'-O-MOE-rG(iBu)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite
Description: 5'-O-DMT-2'-O-MOE-rG(iBu)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite, utilized in oligonucleotide synthesis, features a 5'-O-DMT protecting group and contains a diisopropylamino group for coupling with the next nucleotide. The nucleoside unit is guanosine (rG), modified with a 2'-O-methoxyethyl (MOE) group and isobutyryl (iBu) protection on the guanine amino group. It also contains a phosphoramidite group for solid-phase synthesis. It finds application in the construction of RNA sequences with enhanced stability and target specificity, suitable for various research applications including RNA-based therapeutics and gene editing.
CAT: BRP-00604
Molecular Formula: C55H78N8O12P2
Molecular Weight: 1105.22
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: LVJZCNKMRFOXEH-XOHXKFSOSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)ethyl) diisopropylphosphoramidite
InChI: InChI=1S/C55H78N8O12P2/c1-36(2)51(64)59-54-58-50-47(52(65)60-54)57-35-61(50)53-49(69-31-30-66-11)48(75-77(63(39(7)8)40(9)10)73-33-32-72-76(71-29-17-28-56)62(37(3)4)38(5)6)46(74-53)34-70-55(41-18-15-14-16-19-41,42-20-24-44(67-12)25-21-42)43-22-26-45(68-13)27-23-43/h14-16,18-27,35-40,46,48-49,53H,17,29-34H2,1-13H3,(H2,58,59,60,64,65)/t46-,48-,49-,53-,76?,77?/m1/s1
-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite.gif)
5'-O-DMT-2'-O-MOE-5-Me-rC(Bz)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite
Description: 5'-O-DMT-2'-O-MOE-5-Me-rC(Bz)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite, employed in oligonucleotide synthesis, features a 5'-O-DMT protecting group and contains a diisopropylamino group for coupling with the next nucleotide. The nucleoside unit is 5-methylcytidine (5-Me-rC), modified with a 2'-O-methoxyethyl (MOE) group and benzoyl (Bz) protection on the cytosine amino group. Additionally, it contains a phosphoramidite group for solid-phase synthesis. The presence of a cyanoethoxy group at the 3'-end facilitates efficient coupling reactions during synthesis. This compound is valuable in generating modified RNA sequences with enhanced stability and target specificity, suitable for various research applications including RNA-based therapeutics and gene editing.
CAT: BRP-00605
Molecular Formula: C58H78N6O12P2
Molecular Weight: 1113.24
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: GEBJJSSJUVBPKC-UBMNREJOSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)ethyl) diisopropylphosphoramidite
InChI: InChI=1S/C58H78N6O12P2/c1-40(2)63(41(3)4)77(72-33-19-32-59)73-36-37-74-78(64(42(5)6)43(7)8)76-52-51(39-71-58(46-22-17-14-18-23-46,47-24-28-49(68-11)29-25-47)48-26-30-50(69-12)31-27-48)75-56(53(52)70-35-34-67-10)62-38-44(9)54(61-57(62)66)60-55(65)45-20-15-13-16-21-45/h13-18,20-31,38,40-43,51-53,56H,19,33-37,39H2,1-12H3,(H,60,61,65,66)/t51-,52-,53-,56-,77?,78?/m1/s1
-3'-oxy)-bis(diisopropylphosphoramidite).gif)
ethane-1,2-di(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-bis(diisopropylphosphoramidite)
Description: ethane-1,2-di(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-bis(diisopropylphosphoramidite) is employed in the solid-phase synthesis of oligonucleotides with specific modifications, enhancing their stability and target affinity for applications in molecular biology and biotechnology.
CAT: BRP-00606
Molecular Formula: C96H116N8O20P2
Molecular Weight: 1763.97
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: ZRLNUNRPDXULMT-SUWRQQMKSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) ethane-1,2-diyl bis(diisopropylphosphoramidite)
InChI: InChI=1S/C96H116N8O20P2/c1-63(2)103(64(3)4)125(123-83-81(61-117-95(71-33-25-19-26-34-71,73-37-45-77(111-13)46-38-73)74-39-47-78(112-14)48-40-74)121-91(85(83)115-55-53-109-11)101-59-67(9)87(99-93(101)107)97-89(105)69-29-21-17-22-30-69)119-57-58-120-126(104(65(5)6)66(7)8)124-84-82(62-118-96(72-35-27-20-28-36-72,75-41-49-79(113-15)50-42-75)76-43-51-80(114-16)52-44-76)122-92(86(84)116-56-54-110-12)102-60-68(10)88(100-94(102)108)98-90(106)70-31-23-18-24-32-70/h17-52,59-60,63-66,81-86,91-92H,53-58,61-62H2,1-16H3,(H,97,99,105,107)(H,98,100,106,108)/t81-,82-,83-,84-,85-,86-,91-,92-,125?,126?/m1/s1
-3'-oxy)-bis(diisopropylphosphoramidite).gif)
ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-bis(diisopropylphosphoramidite)
Description: ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-bis(diisopropylphosphoramidite) is utilized in the solid-phase synthesis of oligonucleotides with specific modifications, enhancing their stability and target affinity for applications in molecular biology and biotechnology.
CAT: BRP-00607
Molecular Formula: C96H112N12O18P2
Molecular Weight: 1783.97
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: JUHDGWSQBXOHFV-IFGMRGENSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) ethane-1,2-diyl bis(diisopropylphosphoramidite)
InChI: InChI=1S/C96H112N12O18P2/c1-63(2)107(64(3)4)127(125-83-79(57-119-95(69-31-23-17-24-32-69,71-35-43-75(113-11)44-36-71)72-37-45-76(114-12)46-38-72)123-93(85(83)117-53-51-111-9)105-61-101-81-87(97-59-99-89(81)105)103-91(109)67-27-19-15-20-28-67)121-55-56-122-128(108(65(5)6)66(7)8)126-84-80(58-120-96(70-33-25-18-26-34-70,73-39-47-77(115-13)48-40-73)74-41-49-78(116-14)50-42-74)124-94(86(84)118-54-52-112-10)106-62-102-82-88(98-60-100-90(82)106)104-92(110)68-29-21-16-22-30-68/h15-50,59-66,79-80,83-86,93-94H,51-58H2,1-14H3,(H,97,99,103,109)(H,98,100,104,110)/t79-,80-,83-,84-,85-,86-,93-,94-,127?,128?/m1/s1
-3'-oxy)-bis(diisopropylphosphoramidite).gif)
ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-bis(diisopropylphosphoramidite)
Description: ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-bis(diisopropylphosphoramidite) is employed in the solid-phase synthesis of oligonucleotides with specific modifications, enhancing their stability and target affinity for applications in molecular biology and biotechnology.
CAT: BRP-00608
Molecular Formula: C90H116N12O20P2
Molecular Weight: 1747.93
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: DJTWFMQESYMPJM-FHQSMYATSA-N
IUPAC Name: bis((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) ethane-1,2-diyl bis(diisopropylphosphoramidite)
InChI: InChI=1S/C90H116N12O20P2/c1-55(2)81(103)95-87-93-79-73(83(105)97-87)91-53-99(79)85-77(113-47-45-107-13)75(71(119-85)51-115-89(61-25-21-19-22-26-61,63-29-37-67(109-15)38-30-63)64-31-39-68(110-16)40-32-64)121-123(101(57(5)6)58(7)8)117-49-50-118-124(102(59(9)10)60(11)12)122-76-72(120-86(78(76)114-48-46-108-14)100-54-92-74-80(100)94-88(98-84(74)106)96-82(104)56(3)4)52-116-90(62-27-23-20-24-28-62,65-33-41-69(111-17)42-34-65)66-35-43-70(112-18)44-36-66/h19-44,53-60,71-72,75-78,85-86H,45-52H2,1-18H3,(H2,93,95,97,103,105)(H2,94,96,98,104,106)/t71-,72-,75-,76-,77-,78-,85-,86-,123?,124?/m1/s1
-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite).gif)
di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)
Description: di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) consists of two molecules of 5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy connected by an ethane-1,2-diyl linker, with each end functionalized with a diisopropylphosphoramidite group. The guanosine (rG) nucleoside units are modified with a 2'-O-methoxyethyl (MOE) group and isobutyryl (iBu) protection on the guanine amino group. This compound is utilized in oligonucleotide synthesis for the introduction of guanosine modifications, enhancing stability and target specificity in RNA sequences.
CAT: BRP-00609
Molecular Formula: C92H120N12O21P2
Molecular Weight: 1791.98
Purity: ≥92%
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| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: MSPWBBNFOKRACO-QBSMUBNASA-N
IUPAC Name: bis((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) (oxybis(ethane-2,1-diyl)) bis(diisopropylphosphoramidite)
InChI: InChI=1S/C92H120N12O21P2/c1-57(2)83(105)97-89-95-81-75(85(107)99-89)93-55-101(81)87-79(116-49-45-109-13)77(73(122-87)53-118-91(63-25-21-19-22-26-63,65-29-37-69(111-15)38-30-65)66-31-39-70(112-16)40-32-66)124-126(103(59(5)6)60(7)8)120-51-47-115-48-52-121-127(104(61(9)10)62(11)12)125-78-74(123-88(80(78)117-50-46-110-14)102-56-94-76-82(102)96-90(100-86(76)108)98-84(106)58(3)4)54-119-92(64-27-23-20-24-28-64,67-33-41-71(113-17)42-34-67)68-35-43-72(114-18)44-36-68/h19-44,55-62,73-74,77-80,87-88H,45-54H2,1-18H3,(H2,95,97,99,105,107)(H2,96,98,100,106,108)/t73-,74-,77-,78-,79-,80-,87-,88-,126?,127?/m1/s1
-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite).gif)
di(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)
Description: di(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) contains two molecules of 5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy linked by an ethane-1,2-diyl linker, with each end capped with a diisopropylphosphoramidite group. The adenosine (rA) nucleoside units are modified with a 2'-O-methoxyethyl (MOE) group and benzoyl (Bz) protection on the adenine amino group. It is employed in oligonucleotide synthesis to incorporate adenosine modifications, enhancing stability and target affinity in RNA sequences.
CAT: BRP-00610
Molecular Formula: C98H116N12O19P2
Molecular Weight: 1828.02
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: HYMLNNFAMXTLQA-DEYJQIQZSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) (oxybis(ethane-2,1-diyl)) bis(diisopropylphosphoramidite)
InChI: InChI=1S/C98H116N12O19P2/c1-65(2)109(66(3)4)130(128-85-81(59-122-97(71-31-23-17-24-32-71,73-35-43-77(115-11)44-36-73)74-37-45-78(116-12)46-38-74)126-95(87(85)120-55-51-113-9)107-63-103-83-89(99-61-101-91(83)107)105-93(111)69-27-19-15-20-28-69)124-57-53-119-54-58-125-131(110(67(5)6)68(7)8)129-86-82(60-123-98(72-33-25-18-26-34-72,75-39-47-79(117-13)48-40-75)76-41-49-80(118-14)50-42-76)127-96(88(86)121-56-52-114-10)108-64-104-84-90(100-62-102-92(84)108)106-94(112)70-29-21-16-22-30-70/h15-50,61-68,81-82,85-88,95-96H,51-60H2,1-14H3,(H,99,101,105,111)(H,100,102,106,112)/t81-,82-,85-,86-,87-,88-,95-,96-,130?,131?/m1/s1
-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite).gif)
di(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)
Description: di(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) features two molecules of 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy connected by an ethane-1,2-diyl linker, with each end bearing a diisopropylphosphoramidite group. The 5-methylcytidine (5-Me-rC) nucleoside units are modified with a 2'-O-methoxyethyl (MOE) group and benzoyl (Bz) protection on the cytosine amino group. It is utilized in oligonucleotide synthesis for introducing modified cytidine residues, enhancing stability and target specificity in RNA sequences.
CAT: BRP-00611
Molecular Formula: C98H120N8O21P2
Molecular Weight: 1808.02
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: JOFMESXERKIMQK-AFYKGNOXSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) (oxybis(ethane-2,1-diyl)) bis(diisopropylphosphoramidite)
InChI: InChI=1S/C98H120N8O21P2/c1-65(2)105(66(3)4)128(126-85-83(63-120-97(73-33-25-19-26-34-73,75-37-45-79(113-13)46-38-75)76-39-47-80(114-14)48-40-76)124-93(87(85)118-57-53-111-11)103-61-69(9)89(101-95(103)109)99-91(107)71-29-21-17-22-30-71)122-59-55-117-56-60-123-129(106(67(5)6)68(7)8)127-86-84(64-121-98(74-35-27-20-28-36-74,77-41-49-81(115-15)50-42-77)78-43-51-82(116-16)52-44-78)125-94(88(86)119-58-54-112-12)104-62-70(10)90(102-96(104)110)100-92(108)72-31-23-18-24-32-72/h17-52,61-62,65-68,83-88,93-94H,53-60,63-64H2,1-16H3,(H,99,101,107,109)(H,100,102,108,110)/t83-,84-,85-,86-,87-,88-,93-,94-,128?,129?/m1/s1
-3'-oxy)-diisopropylphosphoramidite.gif)
Bis(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-diisopropylphosphoramidite
Description: Bis(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-diisopropylphosphoramidite consists of two molecules of 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy linked by a diisopropylphosphoramidite group. Each 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy unit is equipped with a diisopropylphosphoramidite group, facilitating its integration into oligonucleotide synthesis. It is used to introduce modified 5-methylcytidine (5-Me-rC) residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00612
Molecular Formula: C88H98N7O18P
Molecular Weight: 1572.73
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: SISSXAOEXVVHFI-QEZASILESA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) diisopropylphosphoramidite
InChI: InChI=1S/C88H98N7O18P/c1-57(2)95(58(3)4)114(112-75-73(55-108-87(63-29-21-15-22-30-63,65-33-41-69(102-9)42-34-65)66-35-43-70(103-10)44-36-66)110-83(77(75)106-51-49-100-7)93-53-59(5)79(91-85(93)98)89-81(96)61-25-17-13-18-26-61)113-76-74(56-109-88(64-31-23-16-24-32-64,67-37-45-71(104-11)46-38-67)68-39-47-72(105-12)48-40-68)111-84(78(76)107-52-50-101-8)94-54-60(6)80(92-86(94)99)90-82(97)62-27-19-14-20-28-62/h13-48,53-54,57-58,73-78,83-84H,49-52,55-56H2,1-12H3,(H,89,91,96,98)(H,90,92,97,99)/t73-,74-,75-,76-,77-,78-,83-,84-/m1/s1
-3'-oxy)-diisopropylphosphoramidite.gif)
Bis(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-diisopropylphosphoramidite
Description: Bis(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-diisopropylphosphoramidite comprises two molecules of 5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy linked by a diisopropylphosphoramidite group. Each 5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy unit is equipped with a diisopropylphosphoramidite group, facilitating its integration into oligonucleotide synthesis. It is utilized to introduce modified guanosine (rG) residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00613
Molecular Formula: C82H98N11O18P
Molecular Weight: 1556.72
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: BXMZUGBTEMISAL-APUMCEBKSA-N
IUPAC Name: bis((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) diisopropylphosphoramidite
InChI: InChI=1S/C82H98N11O18P/c1-49(2)73(94)87-79-85-71-65(75(96)89-79)83-47-91(71)77-69(104-43-41-98-9)67(63(108-77)45-106-81(53-21-17-15-18-22-53,55-25-33-59(100-11)34-26-55)56-27-35-60(101-12)36-28-56)110-112(93(51(5)6)52(7)8)111-68-64(109-78(70(68)105-44-42-99-10)92-48-84-66-72(92)86-80(90-76(66)97)88-74(95)50(3)4)46-107-82(54-23-19-16-20-24-54,57-29-37-61(102-13)38-30-57)58-31-39-62(103-14)40-32-58/h15-40,47-52,63-64,67-70,77-78H,41-46H2,1-14H3,(H2,85,87,89,94,96)(H2,86,88,90,95,97)/t63-,64-,67-,68-,69-,70-,77-,78-/m1/s1
-3'-oxy)-diisopropylphosphoramidite.gif)
Bis(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-diisopropylphosphoramidite
Description: Bis(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-diisopropylphosphoramidite consists of two molecules of 5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy linked by a diisopropylphosphoramidite group. Each 5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy unit is equipped with a diisopropylphosphoramidite group, facilitating its integration into oligonucleotide synthesis. It is used to introduce modified adenosine (rA) residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00614
Molecular Formula: C88H94N11O16P
Molecular Weight: 1592.75
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: SSMWHJUZANQYIO-BDXQTOLXSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) diisopropylphosphoramidite
InChI: InChI=1S/C88H94N11O16P/c1-57(2)99(58(3)4)116(114-75-71(51-110-87(61-27-19-13-20-28-61,63-31-39-67(104-7)40-32-63)64-33-41-68(105-8)42-34-64)112-85(77(75)108-49-47-102-5)97-55-93-73-79(89-53-91-81(73)97)95-83(100)59-23-15-11-16-24-59)115-76-72(52-111-88(62-29-21-14-22-30-62,65-35-43-69(106-9)44-36-65)66-37-45-70(107-10)46-38-66)113-86(78(76)109-50-48-103-6)98-56-94-74-80(90-54-92-82(74)98)96-84(101)60-25-17-12-18-26-60/h11-46,53-58,71-72,75-78,85-86H,47-52H2,1-10H3,(H,89,91,95,100)(H,90,92,96,101)/t71-,72-,75-,76-,77-,78-,85-,86-/m1/s1
-3'-ce-phosphoramidite.gif)
DMTr-2'-O-EOE-rA(Bz)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-EOE-rA(Bz)-3'-CE-Phosphoramidite is used in oligonucleotide synthesis and contains a 2'-O-ethoxyethyl (EOE) group at the 2'-position of adenosine (rA), along with benzoyl (Bz) protection on the adenine amino group. Additionally, it features a cyanoethyl (CE) group at the 3'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified adenosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00615
Molecular Formula: C51H60N7O9P
Molecular Weight: 946.05
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: FXYAXMLJVORSBX-SXQANJJUSA-N
CanonicalSMILES: CCOCCOC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-(2-ethoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C51H60N7O9P/c1-8-62-30-31-63-46-45(67-68(65-29-15-28-52)58(35(2)3)36(4)5)43(66-50(46)57-34-55-44-47(53-33-54-48(44)57)56-49(59)37-16-11-9-12-17-37)32-64-51(38-18-13-10-14-19-38,39-20-24-41(60-6)25-21-39)40-22-26-42(61-7)27-23-40/h9-14,16-27,33-36,43,45-46,50H,8,15,29-32H2,1-7H3,(H,53,54,56,59)/t43-,45-,46-,50-,68?/m1/s1
Synonyms: (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-ethoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
DMTr-2'-O-EOE-rG(iBu)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-EOE-rG(iBu)-3'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, features a 2'-O-ethoxyethyl (EOE) group at the 2'-position of guanosine (rG), with isobutyryl (iBu) protection on the guanine amino group. It also contains a cyanoethyl (CE) group at the 3'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified guanosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00616
CAS: 2253990-02-0
Molecular Formula: C48H62N7O10P
Molecular Weight: 928.04
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: FIYLELGPQAAWKS-USWYRWCRSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OCCOCC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-ethoxyethoxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C48H62N7O10P/c1-10-60-27-28-61-42-41(65-66(63-26-14-25-49)55(32(4)5)33(6)7)39(64-46(42)54-30-50-40-43(54)51-47(53-45(40)57)52-44(56)31(2)3)29-62-48(34-15-12-11-13-16-34,35-17-21-37(58-8)22-18-35)36-19-23-38(59-9)24-20-36/h11-13,15-24,30-33,39,41-42,46H,10,14,26-29H2,1-9H3,(H2,51,52,53,56,57)/t39-,41-,42-,46-,66?/m1/s1
-3'-ce-phosphoramidite.gif)
DMTr-2'-O-EOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-EOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis and contains a 2'-O-ethoxyethyl (EOE) group at the 2'-position of 5-methylcytidine (5-Me-rC), along with benzoyl (Bz) protection on the cytosine amino group. Additionally, it features a cyanoethyl (CE) group at the 3'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified 5-methylcytidine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00617
Molecular Formula: C51H62N5O10P
Molecular Weight: 936.06
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: GFURHQMVDLZCAG-JMTVAXSASA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-ethoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C51H62N5O10P/c1-9-61-31-32-62-46-45(66-67(64-30-16-29-52)56(35(2)3)36(4)5)44(65-49(46)55-33-37(6)47(54-50(55)58)53-48(57)38-17-12-10-13-18-38)34-63-51(39-19-14-11-15-20-39,40-21-25-42(59-7)26-22-40)41-23-27-43(60-8)28-24-41/h10-15,17-28,33,35-36,44-46,49H,9,16,30-32,34H2,1-8H3,(H,53,54,57,58)/t44-,45-,46-,49-,67?/m1/s1
DMTr-3'-O-MOE-5-Me-rC(Bz)-2'-CE-Phosphoramidite
Description: DMTr-3'-O-MOE-5-Me-rC(Bz)-2'-CE-Phosphoramidite is used in oligonucleotide synthesis and contains a 3'-O-methoxyethyl (MOE) group at the 3'-position of 5-methylcytidine (5-Me-rC), with benzoyl (Bz) protection on the cytosine amino group. Additionally, it features a cyanoethyl (CE) group at the 2'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified 5-methylcytidine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00618
CAS: 1098233-10-3
Molecular Formula: C50H60N5O10P
Molecular Weight: 922.03
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: GOMXXEFGGBGLGJ-GICDFOIUSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OCCOC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-(2-methoxyethoxy)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C50H60N5O10P/c1-34(2)55(35(3)4)66(63-29-15-28-51)65-45-44(61-31-30-58-6)43(64-48(45)54-32-36(5)46(53-49(54)57)52-47(56)37-16-11-9-12-17-37)33-62-50(38-18-13-10-14-19-38,39-20-24-41(59-7)25-21-39)40-22-26-42(60-8)27-23-40/h9-14,16-27,32,34-35,43-45,48H,15,29-31,33H2,1-8H3,(H,52,53,56,57)/t43-,44-,45-,48-,66?/m1/s1
Synonyms: 3'-O-MOE-5Me-C(Bz)-2'-phosphoramidite; N4-Bz-5'-O-DMTr-3'-O-(2-methoxyethyl)-5-methyl cytidine-2'-CED-phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-(2-methoxyethyl)-5-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
DMTr-3'-O-MOE-rA(Bz)-2'-CE-Phosphoramidite
Description: DMTr-3'-O-MOE-rA(Bz)-2'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, features a 3'-O-methoxyethyl (MOE) group at the 3'-position of adenosine (rA), with benzoyl (Bz) protection on the adenine amino group. It also contains a cyanoethyl (CE) group at the 2'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified adenosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00619
CAS: 256224-01-8
Molecular Formula: C50H58N7O9P
Molecular Weight: 932.03
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: FODCLDRFHMYZMX-HDMAWCRFSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OCCOC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C50H58N7O9P/c1-34(2)57(35(3)4)67(64-28-14-27-51)66-45-44(62-30-29-59-5)42(65-49(45)56-33-54-43-46(52-32-53-47(43)56)55-48(58)36-15-10-8-11-16-36)31-63-50(37-17-12-9-13-18-37,38-19-23-40(60-6)24-20-38)39-21-25-41(61-7)26-22-39/h8-13,15-26,32-35,42,44-45,49H,14,28-31H2,1-7H3,(H,52,53,55,58)/t42-,44-,45-,49-,67?/m1/s1
Synonyms: 3'-O-MOE-A(Bz)-2'-CED-phosphoramidite; (2R,3R,4R,5R)-2-(6-Benzamido-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-(2-methoxyethyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N6-Bz-5'-O-DMTr-3'-O-(2-methoxyethyl) adenosine-2'-CED-phosphoramidite
DMTr-3'-O-MOE-rG(iBu)-2'-CE-Phosphoramidite
Description: DMTr-3'-O-MOE-rG(iBu)-2'-CE-Phosphoramidite is utilized in oligonucleotide synthesis and contains a 3'-O-methoxyethyl (MOE) group at the 3'-position of guanosine (rG), with isobutyryl (iBu) protection on the guanine amino group. Additionally, it features a cyanoethyl (CE) group at the 2'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified guanosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00620
CAS: 256224-06-3
Molecular Formula: C47H60N7O10P
Molecular Weight: 914.01
Purity: ≥95%
Appearance: White to off-white foam solid
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Storage: Store at -20 °C, under inert atmosphere
InChIKey: BWLKVJLYUDLOLH-SBCRAQIVSA-N
Solubility: Soluble in Acetone, Chloroform, DMSO, Ethanol, Methanol
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OCCOC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C47H60N7O10P/c1-30(2)43(55)51-46-50-42-39(44(56)52-46)49-29-53(42)45-41(64-65(62-25-13-24-48)54(31(3)4)32(5)6)40(60-27-26-57-7)38(63-45)28-61-47(33-14-11-10-12-15-33,34-16-20-36(58-8)21-17-34)35-18-22-37(59-9)23-19-35/h10-12,14-23,29-32,38,40-41,45H,13,25-28H2,1-9H3,(H2,50,51,52,55,56)/t38-,40-,41-,45-,65?/m1/s1
Synonyms: 3'-O-MOE-G(iBu)-2'-phosphoramidite; 5'-O-DMTr-N2-iso-butyroyl-3'-O-(2-methoxyethyl)guanosine-2'-CED-phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 5'-O-(4,4'-Dimethoxytrityl)-N2-iso-butyroyl-3'-O-(2-methoxyethyl)guanosine-2'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite
