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2'-Modified Phosphoramidites
(466/466) 2'-Phosphoramidites
(21/21) 3'-Modified Phosphoramidites
(186/186) 5'-Modified Phosphoramidites
(21/21) Arabino Phosphoramidites
(19/19) Base Protected Phosphoramidites (365/365) Dye Phosphoramidites
(53/53) Label Phosphoramidites
(82/82) Linker Phosphoramidites
(72/72) Other Phosphoramidites
(92/92) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(15/15) Spacer Phosphoramidites
(22/22)
(466/466) 2'-Phosphoramidites
(21/21) 3'-Modified Phosphoramidites
(186/186) 5'-Modified Phosphoramidites
(21/21) Arabino Phosphoramidites
(19/19) Base Protected Phosphoramidites (365/365) Dye Phosphoramidites
(53/53) Label Phosphoramidites
(82/82) Linker Phosphoramidites
(72/72) Other Phosphoramidites
(92/92) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(15/15) Spacer Phosphoramidites
(22/22)
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DMTr-2'-O-4'-C-ethylene-rG(iBu)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-4'-C-ethylene-rG(iBu)-3'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, features an ethylene linker at the 2'-O and 4'-C positions of guanosine (rG), with isobutyryl (iBu) protection on the guanine amino group. The cyanoethyl (CE) group at the 3'-end facilitates efficient coupling reactions during solid-phase synthesis. This modified nucleotide is valuable for generating RNA sequences with enhanced stability and binding affinity, suitable for applications such as RNA interference (RNAi) and RNA therapeutics.
CAT: BRP-00601
CAS: 287737-58-0
MF: C46H56N7O9P
MF: 881.97
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: VXCXNHPZXAIEDO-DNUXVXCXSA-N
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C4C(C(O3)(CCO4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(1R,5R,7R,8S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-8-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,6-dioxabicyclo[3.2.1]octan-7-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C46H56N7O9P/c1-29(2)41(54)50-44-49-40-37(42(55)51-44)48-28-52(40)43-38-39(62-63(60-25-12-24-47)53(30(3)4)31(5)6)45(61-43,23-26-58-38)27-59-46(32-13-10-9-11-14-32,33-15-19-35(56-7)20-16-33)34-17-21-36(57-8)22-18-34/h9-11,13-22,28-31,38-39,43H,12,23,25-27H2,1-8H3,(H2,49,50,51,54,55)/t38-,39+,43-,45-,63?/m1/s1
Synonyms: ENA-G(iBu) Phosphoramidite; N-[9-[2,6-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5-deoxy-α-L-lyxo-hexofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropanamide; (1R,5R,7R,8S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-2,6-dioxabicyclo[3.2.1]octan-8-yl (2-cyanoethyl) diisopropylphosphoramidite
DMTr-2'-O-C22-rA(Bz)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-C22-rA(Bz)-3'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, contains a DMTr protecting group at the 5'-position and a cyanoethyl (CE) group at the 3'-end. The nucleoside unit is adenosine (rA), modified with a C22 linker at the 2'-O position and benzoyl (Bz) protection on the adenine amino group. It is employed in the synthesis of RNA sequences with enhanced stability and binding affinity, suitable for various research applications including RNA-based therapy and gene expression modulation.
CAT: BRP-00603
CAS: 2923115-67-5
MF: C69H96N7O8P
MF: 1182.54
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: BCBFIURHCBIJCZ-GOQGTMNZSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=NC=NC32)NC(=O)C=4C=CC=CC4)C1OCCCCCCCCCCCCCCCCCCCCCC)COC(C=5C=CC=CC5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(docosyloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C69H96N7O8P/c1-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-33-48-80-64-63(84-85(82-49-34-47-70)76(53(2)3)54(4)5)61(83-68(64)75-52-73-62-65(71-51-72-66(62)75)74-67(77)55-35-29-27-30-36-55)50-81-69(56-37-31-28-32-38-56,57-39-43-59(78-6)44-40-57)58-41-45-60(79-7)46-42-58/h27-32,35-46,51-54,61,63-64,68H,8-26,33-34,48-50H2,1-7H3,(H,71,72,74,77)/t61-,63-,64-,68-,85?/m1/s1
-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite.gif)
5'-O-DMT-2'-O-MOE-rG(iBu)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite
Description: 5'-O-DMT-2'-O-MOE-rG(iBu)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite, utilized in oligonucleotide synthesis, features a 5'-O-DMT protecting group and contains a diisopropylamino group for coupling with the next nucleotide. The nucleoside unit is guanosine (rG), modified with a 2'-O-methoxyethyl (MOE) group and isobutyryl (iBu) protection on the guanine amino group. It also contains a phosphoramidite group for solid-phase synthesis. It finds application in the construction of RNA sequences with enhanced stability and target specificity, suitable for various research applications including RNA-based therapeutics and gene editing.
CAT: BRP-00604
MF: C55H78N8O12P2
MF: 1105.22
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: LVJZCNKMRFOXEH-XOHXKFSOSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)ethyl) diisopropylphosphoramidite
InChI: InChI=1S/C55H78N8O12P2/c1-36(2)51(64)59-54-58-50-47(52(65)60-54)57-35-61(50)53-49(69-31-30-66-11)48(75-77(63(39(7)8)40(9)10)73-33-32-72-76(71-29-17-28-56)62(37(3)4)38(5)6)46(74-53)34-70-55(41-18-15-14-16-19-41,42-20-24-44(67-12)25-21-42)43-22-26-45(68-13)27-23-43/h14-16,18-27,35-40,46,48-49,53H,17,29-34H2,1-13H3,(H2,58,59,60,64,65)/t46-,48-,49-,53-,76?,77?/m1/s1
-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite.gif)
5'-O-DMT-2'-O-MOE-5-Me-rC(Bz)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite
Description: 5'-O-DMT-2'-O-MOE-5-Me-rC(Bz)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite, employed in oligonucleotide synthesis, features a 5'-O-DMT protecting group and contains a diisopropylamino group for coupling with the next nucleotide. The nucleoside unit is 5-methylcytidine (5-Me-rC), modified with a 2'-O-methoxyethyl (MOE) group and benzoyl (Bz) protection on the cytosine amino group. Additionally, it contains a phosphoramidite group for solid-phase synthesis. The presence of a cyanoethoxy group at the 3'-end facilitates efficient coupling reactions during synthesis. This compound is valuable in generating modified RNA sequences with enhanced stability and target specificity, suitable for various research applications including RNA-based therapeutics and gene editing.
CAT: BRP-00605
MF: C58H78N6O12P2
MF: 1113.24
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: GEBJJSSJUVBPKC-UBMNREJOSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)ethyl) diisopropylphosphoramidite
InChI: InChI=1S/C58H78N6O12P2/c1-40(2)63(41(3)4)77(72-33-19-32-59)73-36-37-74-78(64(42(5)6)43(7)8)76-52-51(39-71-58(46-22-17-14-18-23-46,47-24-28-49(68-11)29-25-47)48-26-30-50(69-12)31-27-48)75-56(53(52)70-35-34-67-10)62-38-44(9)54(61-57(62)66)60-55(65)45-20-15-13-16-21-45/h13-18,20-31,38,40-43,51-53,56H,19,33-37,39H2,1-12H3,(H,60,61,65,66)/t51-,52-,53-,56-,77?,78?/m1/s1
-3'-oxy)-bis(diisopropylphosphoramidite).gif)
ethane-1,2-di(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-bis(diisopropylphosphoramidite)
Description: ethane-1,2-di(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-bis(diisopropylphosphoramidite) is employed in the solid-phase synthesis of oligonucleotides with specific modifications, enhancing their stability and target affinity for applications in molecular biology and biotechnology.
CAT: BRP-00606
MF: C96H116N8O20P2
MF: 1763.97
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: ZRLNUNRPDXULMT-SUWRQQMKSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) ethane-1,2-diyl bis(diisopropylphosphoramidite)
InChI: InChI=1S/C96H116N8O20P2/c1-63(2)103(64(3)4)125(123-83-81(61-117-95(71-33-25-19-26-34-71,73-37-45-77(111-13)46-38-73)74-39-47-78(112-14)48-40-74)121-91(85(83)115-55-53-109-11)101-59-67(9)87(99-93(101)107)97-89(105)69-29-21-17-22-30-69)119-57-58-120-126(104(65(5)6)66(7)8)124-84-82(62-118-96(72-35-27-20-28-36-72,75-41-49-79(113-15)50-42-75)76-43-51-80(114-16)52-44-76)122-92(86(84)116-56-54-110-12)102-60-68(10)88(100-94(102)108)98-90(106)70-31-23-18-24-32-70/h17-52,59-60,63-66,81-86,91-92H,53-58,61-62H2,1-16H3,(H,97,99,105,107)(H,98,100,106,108)/t81-,82-,83-,84-,85-,86-,91-,92-,125?,126?/m1/s1
-3'-oxy)-bis(diisopropylphosphoramidite).gif)
ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-bis(diisopropylphosphoramidite)
Description: ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-bis(diisopropylphosphoramidite) is utilized in the solid-phase synthesis of oligonucleotides with specific modifications, enhancing their stability and target affinity for applications in molecular biology and biotechnology.
CAT: BRP-00607
MF: C96H112N12O18P2
MF: 1783.97
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: JUHDGWSQBXOHFV-IFGMRGENSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) ethane-1,2-diyl bis(diisopropylphosphoramidite)
InChI: InChI=1S/C96H112N12O18P2/c1-63(2)107(64(3)4)127(125-83-79(57-119-95(69-31-23-17-24-32-69,71-35-43-75(113-11)44-36-71)72-37-45-76(114-12)46-38-72)123-93(85(83)117-53-51-111-9)105-61-101-81-87(97-59-99-89(81)105)103-91(109)67-27-19-15-20-28-67)121-55-56-122-128(108(65(5)6)66(7)8)126-84-80(58-120-96(70-33-25-18-26-34-70,73-39-47-77(115-13)48-40-73)74-41-49-78(116-14)50-42-74)124-94(86(84)118-54-52-112-10)106-62-102-82-88(98-60-100-90(82)106)104-92(110)68-29-21-16-22-30-68/h15-50,59-66,79-80,83-86,93-94H,51-58H2,1-14H3,(H,97,99,103,109)(H,98,100,104,110)/t79-,80-,83-,84-,85-,86-,93-,94-,127?,128?/m1/s1
-3'-oxy)-bis(diisopropylphosphoramidite).gif)
ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-bis(diisopropylphosphoramidite)
Description: ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-bis(diisopropylphosphoramidite) is employed in the solid-phase synthesis of oligonucleotides with specific modifications, enhancing their stability and target affinity for applications in molecular biology and biotechnology.
CAT: BRP-00608
MF: C90H116N12O20P2
MF: 1747.93
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: DJTWFMQESYMPJM-FHQSMYATSA-N
IUPAC Name: bis((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) ethane-1,2-diyl bis(diisopropylphosphoramidite)
InChI: InChI=1S/C90H116N12O20P2/c1-55(2)81(103)95-87-93-79-73(83(105)97-87)91-53-99(79)85-77(113-47-45-107-13)75(71(119-85)51-115-89(61-25-21-19-22-26-61,63-29-37-67(109-15)38-30-63)64-31-39-68(110-16)40-32-64)121-123(101(57(5)6)58(7)8)117-49-50-118-124(102(59(9)10)60(11)12)122-76-72(120-86(78(76)114-48-46-108-14)100-54-92-74-80(100)94-88(98-84(74)106)96-82(104)56(3)4)52-116-90(62-27-23-20-24-28-62,65-33-41-69(111-17)42-34-65)66-35-43-70(112-18)44-36-66/h19-44,53-60,71-72,75-78,85-86H,45-52H2,1-18H3,(H2,93,95,97,103,105)(H2,94,96,98,104,106)/t71-,72-,75-,76-,77-,78-,85-,86-,123?,124?/m1/s1
-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite).gif)
di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)
Description: di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) consists of two molecules of 5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy connected by an ethane-1,2-diyl linker, with each end functionalized with a diisopropylphosphoramidite group. The guanosine (rG) nucleoside units are modified with a 2'-O-methoxyethyl (MOE) group and isobutyryl (iBu) protection on the guanine amino group. This compound is utilized in oligonucleotide synthesis for the introduction of guanosine modifications, enhancing stability and target specificity in RNA sequences.
CAT: BRP-00609
MF: C92H120N12O21P2
MF: 1791.98
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: MSPWBBNFOKRACO-QBSMUBNASA-N
IUPAC Name: bis((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) (oxybis(ethane-2,1-diyl)) bis(diisopropylphosphoramidite)
InChI: InChI=1S/C92H120N12O21P2/c1-57(2)83(105)97-89-95-81-75(85(107)99-89)93-55-101(81)87-79(116-49-45-109-13)77(73(122-87)53-118-91(63-25-21-19-22-26-63,65-29-37-69(111-15)38-30-65)66-31-39-70(112-16)40-32-66)124-126(103(59(5)6)60(7)8)120-51-47-115-48-52-121-127(104(61(9)10)62(11)12)125-78-74(123-88(80(78)117-50-46-110-14)102-56-94-76-82(102)96-90(100-86(76)108)98-84(106)58(3)4)54-119-92(64-27-23-20-24-28-64,67-33-41-71(113-17)42-34-67)68-35-43-72(114-18)44-36-68/h19-44,55-62,73-74,77-80,87-88H,45-54H2,1-18H3,(H2,95,97,99,105,107)(H2,96,98,100,106,108)/t73-,74-,77-,78-,79-,80-,87-,88-,126?,127?/m1/s1
-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite).gif)
di(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)
Description: di(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) contains two molecules of 5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy linked by an ethane-1,2-diyl linker, with each end capped with a diisopropylphosphoramidite group. The adenosine (rA) nucleoside units are modified with a 2'-O-methoxyethyl (MOE) group and benzoyl (Bz) protection on the adenine amino group. It is employed in oligonucleotide synthesis to incorporate adenosine modifications, enhancing stability and target affinity in RNA sequences.
CAT: BRP-00610
MF: C98H116N12O19P2
MF: 1828.02
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: HYMLNNFAMXTLQA-DEYJQIQZSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) (oxybis(ethane-2,1-diyl)) bis(diisopropylphosphoramidite)
InChI: InChI=1S/C98H116N12O19P2/c1-65(2)109(66(3)4)130(128-85-81(59-122-97(71-31-23-17-24-32-71,73-35-43-77(115-11)44-36-73)74-37-45-78(116-12)46-38-74)126-95(87(85)120-55-51-113-9)107-63-103-83-89(99-61-101-91(83)107)105-93(111)69-27-19-15-20-28-69)124-57-53-119-54-58-125-131(110(67(5)6)68(7)8)129-86-82(60-123-98(72-33-25-18-26-34-72,75-39-47-79(117-13)48-40-75)76-41-49-80(118-14)50-42-76)127-96(88(86)121-56-52-114-10)108-64-104-84-90(100-62-102-92(84)108)106-94(112)70-29-21-16-22-30-70/h15-50,61-68,81-82,85-88,95-96H,51-60H2,1-14H3,(H,99,101,105,111)(H,100,102,106,112)/t81-,82-,85-,86-,87-,88-,95-,96-,130?,131?/m1/s1
-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite).gif)
di(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)
Description: di(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) features two molecules of 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy connected by an ethane-1,2-diyl linker, with each end bearing a diisopropylphosphoramidite group. The 5-methylcytidine (5-Me-rC) nucleoside units are modified with a 2'-O-methoxyethyl (MOE) group and benzoyl (Bz) protection on the cytosine amino group. It is utilized in oligonucleotide synthesis for introducing modified cytidine residues, enhancing stability and target specificity in RNA sequences.
CAT: BRP-00611
MF: C98H120N8O21P2
MF: 1808.02
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: JOFMESXERKIMQK-AFYKGNOXSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) (oxybis(ethane-2,1-diyl)) bis(diisopropylphosphoramidite)
InChI: InChI=1S/C98H120N8O21P2/c1-65(2)105(66(3)4)128(126-85-83(63-120-97(73-33-25-19-26-34-73,75-37-45-79(113-13)46-38-75)76-39-47-80(114-14)48-40-76)124-93(87(85)118-57-53-111-11)103-61-69(9)89(101-95(103)109)99-91(107)71-29-21-17-22-30-71)122-59-55-117-56-60-123-129(106(67(5)6)68(7)8)127-86-84(64-121-98(74-35-27-20-28-36-74,77-41-49-81(115-15)50-42-77)78-43-51-82(116-16)52-44-78)125-94(88(86)119-58-54-112-12)104-62-70(10)90(102-96(104)110)100-92(108)72-31-23-18-24-32-72/h17-52,61-62,65-68,83-88,93-94H,53-60,63-64H2,1-16H3,(H,99,101,107,109)(H,100,102,108,110)/t83-,84-,85-,86-,87-,88-,93-,94-,128?,129?/m1/s1
-3'-oxy)-diisopropylphosphoramidite.gif)
Bis(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-diisopropylphosphoramidite
Description: Bis(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-diisopropylphosphoramidite consists of two molecules of 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy linked by a diisopropylphosphoramidite group. Each 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy unit is equipped with a diisopropylphosphoramidite group, facilitating its integration into oligonucleotide synthesis. It is used to introduce modified 5-methylcytidine (5-Me-rC) residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00612
MF: C88H98N7O18P
MF: 1572.73
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: SISSXAOEXVVHFI-QEZASILESA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) diisopropylphosphoramidite
InChI: InChI=1S/C88H98N7O18P/c1-57(2)95(58(3)4)114(112-75-73(55-108-87(63-29-21-15-22-30-63,65-33-41-69(102-9)42-34-65)66-35-43-70(103-10)44-36-66)110-83(77(75)106-51-49-100-7)93-53-59(5)79(91-85(93)98)89-81(96)61-25-17-13-18-26-61)113-76-74(56-109-88(64-31-23-16-24-32-64,67-37-45-71(104-11)46-38-67)68-39-47-72(105-12)48-40-68)111-84(78(76)107-52-50-101-8)94-54-60(6)80(92-86(94)99)90-82(97)62-27-19-14-20-28-62/h13-48,53-54,57-58,73-78,83-84H,49-52,55-56H2,1-12H3,(H,89,91,96,98)(H,90,92,97,99)/t73-,74-,75-,76-,77-,78-,83-,84-/m1/s1
-3'-oxy)-diisopropylphosphoramidite.gif)
Bis(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-diisopropylphosphoramidite
Description: Bis(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-diisopropylphosphoramidite comprises two molecules of 5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy linked by a diisopropylphosphoramidite group. Each 5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy unit is equipped with a diisopropylphosphoramidite group, facilitating its integration into oligonucleotide synthesis. It is utilized to introduce modified guanosine (rG) residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00613
MF: C82H98N11O18P
MF: 1556.72
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: BXMZUGBTEMISAL-APUMCEBKSA-N
IUPAC Name: bis((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) diisopropylphosphoramidite
InChI: InChI=1S/C82H98N11O18P/c1-49(2)73(94)87-79-85-71-65(75(96)89-79)83-47-91(71)77-69(104-43-41-98-9)67(63(108-77)45-106-81(53-21-17-15-18-22-53,55-25-33-59(100-11)34-26-55)56-27-35-60(101-12)36-28-56)110-112(93(51(5)6)52(7)8)111-68-64(109-78(70(68)105-44-42-99-10)92-48-84-66-72(92)86-80(90-76(66)97)88-74(95)50(3)4)46-107-82(54-23-19-16-20-24-54,57-29-37-61(102-13)38-30-57)58-31-39-62(103-14)40-32-58/h15-40,47-52,63-64,67-70,77-78H,41-46H2,1-14H3,(H2,85,87,89,94,96)(H2,86,88,90,95,97)/t63-,64-,67-,68-,69-,70-,77-,78-/m1/s1
-3'-oxy)-diisopropylphosphoramidite.gif)
Bis(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-diisopropylphosphoramidite
Description: Bis(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-diisopropylphosphoramidite consists of two molecules of 5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy linked by a diisopropylphosphoramidite group. Each 5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy unit is equipped with a diisopropylphosphoramidite group, facilitating its integration into oligonucleotide synthesis. It is used to introduce modified adenosine (rA) residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00614
MF: C88H94N11O16P
MF: 1592.75
Purity: ≥92%
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Storage: Store at -20 °C
InChIKey: SSMWHJUZANQYIO-BDXQTOLXSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) diisopropylphosphoramidite
InChI: InChI=1S/C88H94N11O16P/c1-57(2)99(58(3)4)116(114-75-71(51-110-87(61-27-19-13-20-28-61,63-31-39-67(104-7)40-32-63)64-33-41-68(105-8)42-34-64)112-85(77(75)108-49-47-102-5)97-55-93-73-79(89-53-91-81(73)97)95-83(100)59-23-15-11-16-24-59)115-76-72(52-111-88(62-29-21-14-22-30-62,65-35-43-69(106-9)44-36-65)66-37-45-70(107-10)46-38-66)113-86(78(76)109-50-48-103-6)98-56-94-74-80(90-54-92-82(74)98)96-84(101)60-25-17-12-18-26-60/h11-46,53-58,71-72,75-78,85-86H,47-52H2,1-10H3,(H,89,91,95,100)(H,90,92,96,101)/t71-,72-,75-,76-,77-,78-,85-,86-/m1/s1
-3'-ce-phosphoramidite.gif)
DMTr-2'-O-EOE-rA(Bz)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-EOE-rA(Bz)-3'-CE-Phosphoramidite is used in oligonucleotide synthesis and contains a 2'-O-ethoxyethyl (EOE) group at the 2'-position of adenosine (rA), along with benzoyl (Bz) protection on the adenine amino group. Additionally, it features a cyanoethyl (CE) group at the 3'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified adenosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00615
MF: C51H60N7O9P
MF: 946.05
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: FXYAXMLJVORSBX-SXQANJJUSA-N
CanonicalSMILES: CCOCCOC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-(2-ethoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C51H60N7O9P/c1-8-62-30-31-63-46-45(67-68(65-29-15-28-52)58(35(2)3)36(4)5)43(66-50(46)57-34-55-44-47(53-33-54-48(44)57)56-49(59)37-16-11-9-12-17-37)32-64-51(38-18-13-10-14-19-38,39-20-24-41(60-6)25-21-39)40-22-26-42(61-7)27-23-40/h9-14,16-27,33-36,43,45-46,50H,8,15,29-32H2,1-7H3,(H,53,54,56,59)/t43-,45-,46-,50-,68?/m1/s1
Synonyms: (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-ethoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
DMTr-2'-O-EOE-rG(iBu)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-EOE-rG(iBu)-3'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, features a 2'-O-ethoxyethyl (EOE) group at the 2'-position of guanosine (rG), with isobutyryl (iBu) protection on the guanine amino group. It also contains a cyanoethyl (CE) group at the 3'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified guanosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00616
CAS: 2253990-02-0
MF: C48H62N7O10P
MF: 928.04
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: FIYLELGPQAAWKS-USWYRWCRSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OCCOCC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-ethoxyethoxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C48H62N7O10P/c1-10-60-27-28-61-42-41(65-66(63-26-14-25-49)55(32(4)5)33(6)7)39(64-46(42)54-30-50-40-43(54)51-47(53-45(40)57)52-44(56)31(2)3)29-62-48(34-15-12-11-13-16-34,35-17-21-37(58-8)22-18-35)36-19-23-38(59-9)24-20-36/h11-13,15-24,30-33,39,41-42,46H,10,14,26-29H2,1-9H3,(H2,51,52,53,56,57)/t39-,41-,42-,46-,66?/m1/s1
-3'-ce-phosphoramidite.gif)
DMTr-2'-O-EOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-EOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis and contains a 2'-O-ethoxyethyl (EOE) group at the 2'-position of 5-methylcytidine (5-Me-rC), along with benzoyl (Bz) protection on the cytosine amino group. Additionally, it features a cyanoethyl (CE) group at the 3'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified 5-methylcytidine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00617
MF: C51H62N5O10P
MF: 936.06
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: GFURHQMVDLZCAG-JMTVAXSASA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-ethoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C51H62N5O10P/c1-9-61-31-32-62-46-45(66-67(64-30-16-29-52)56(35(2)3)36(4)5)44(65-49(46)55-33-37(6)47(54-50(55)58)53-48(57)38-17-12-10-13-18-38)34-63-51(39-19-14-11-15-20-39,40-21-25-42(59-7)26-22-40)41-23-27-43(60-8)28-24-41/h10-15,17-28,33,35-36,44-46,49H,9,16,30-32,34H2,1-8H3,(H,53,54,57,58)/t44-,45-,46-,49-,67?/m1/s1
DMTr-3'-O-MOE-5-Me-rC(Bz)-2'-CE-Phosphoramidite
Description: DMTr-3'-O-MOE-5-Me-rC(Bz)-2'-CE-Phosphoramidite is used in oligonucleotide synthesis and contains a 3'-O-methoxyethyl (MOE) group at the 3'-position of 5-methylcytidine (5-Me-rC), with benzoyl (Bz) protection on the cytosine amino group. Additionally, it features a cyanoethyl (CE) group at the 2'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified 5-methylcytidine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00618
CAS: 1098233-10-3
MF: C50H60N5O10P
MF: 922.03
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: GOMXXEFGGBGLGJ-GICDFOIUSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OCCOC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-(2-methoxyethoxy)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C50H60N5O10P/c1-34(2)55(35(3)4)66(63-29-15-28-51)65-45-44(61-31-30-58-6)43(64-48(45)54-32-36(5)46(53-49(54)57)52-47(56)37-16-11-9-12-17-37)33-62-50(38-18-13-10-14-19-38,39-20-24-41(59-7)25-21-39)40-22-26-42(60-8)27-23-40/h9-14,16-27,32,34-35,43-45,48H,15,29-31,33H2,1-8H3,(H,52,53,56,57)/t43-,44-,45-,48-,66?/m1/s1
Synonyms: 3'-O-MOE-5Me-C(Bz)-2'-phosphoramidite; N4-Bz-5'-O-DMTr-3'-O-(2-methoxyethyl)-5-methyl cytidine-2'-CED-phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-(2-methoxyethyl)-5-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
DMTr-3'-O-MOE-rA(Bz)-2'-CE-Phosphoramidite
Description: DMTr-3'-O-MOE-rA(Bz)-2'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, features a 3'-O-methoxyethyl (MOE) group at the 3'-position of adenosine (rA), with benzoyl (Bz) protection on the adenine amino group. It also contains a cyanoethyl (CE) group at the 2'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified adenosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00619
CAS: 256224-01-8
MF: C50H58N7O9P
MF: 932.03
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: FODCLDRFHMYZMX-HDMAWCRFSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OCCOC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C50H58N7O9P/c1-34(2)57(35(3)4)67(64-28-14-27-51)66-45-44(62-30-29-59-5)42(65-49(45)56-33-54-43-46(52-32-53-47(43)56)55-48(58)36-15-10-8-11-16-36)31-63-50(37-17-12-9-13-18-37,38-19-23-40(60-6)24-20-38)39-21-25-41(61-7)26-22-39/h8-13,15-26,32-35,42,44-45,49H,14,28-31H2,1-7H3,(H,52,53,55,58)/t42-,44-,45-,49-,67?/m1/s1
Synonyms: 3'-O-MOE-A(Bz)-2'-CED-phosphoramidite; (2R,3R,4R,5R)-2-(6-Benzamido-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-(2-methoxyethyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N6-Bz-5'-O-DMTr-3'-O-(2-methoxyethyl) adenosine-2'-CED-phosphoramidite
DMTr-3'-O-MOE-rG(iBu)-2'-CE-Phosphoramidite
Description: DMTr-3'-O-MOE-rG(iBu)-2'-CE-Phosphoramidite is utilized in oligonucleotide synthesis and contains a 3'-O-methoxyethyl (MOE) group at the 3'-position of guanosine (rG), with isobutyryl (iBu) protection on the guanine amino group. Additionally, it features a cyanoethyl (CE) group at the 2'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified guanosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00620
CAS: 256224-06-3
MF: C47H60N7O10P
MF: 914.01
Purity: ≥95%
Appearance: White to off-white foam solid
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Storage: Store at -20 °C, under inert atmosphere
InChIKey: BWLKVJLYUDLOLH-SBCRAQIVSA-N
Solubility: Soluble in Acetone, Chloroform, DMSO, Ethanol, Methanol
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OCCOC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C47H60N7O10P/c1-30(2)43(55)51-46-50-42-39(44(56)52-46)49-29-53(42)45-41(64-65(62-25-13-24-48)54(31(3)4)32(5)6)40(60-27-26-57-7)38(63-45)28-61-47(33-14-11-10-12-15-33,34-16-20-36(58-8)21-17-34)35-18-22-37(59-9)23-19-35/h10-12,14-23,29-32,38,40-41,45H,13,25-28H2,1-9H3,(H2,50,51,52,55,56)/t38-,40-,41-,45-,65?/m1/s1
Synonyms: 3'-O-MOE-G(iBu)-2'-phosphoramidite; 5'-O-DMTr-N2-iso-butyroyl-3'-O-(2-methoxyethyl)guanosine-2'-CED-phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 5'-O-(4,4'-Dimethoxytrityl)-N2-iso-butyroyl-3'-O-(2-methoxyethyl)guanosine-2'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite
-3'-ce-phosphoramidite.gif)
DMTr-2'-O-MOEOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite
Description: DMTr-2'-O-MOEOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite, employed in oligonucleotide synthesis, features a methoxyethoxy (MOEOE) group at the 2'-O position and a benzoyl (Bz) protecting group on the 5-methylcytosine (5-Me-rC) amino group. The 3'-end is functionalized with a cyanoethyl (CE) group, facilitating efficient coupling reactions during solid-phase synthesis. It is utilized to introduce modified cytosine residues into nucleic acid sequences, enhancing stability and target specificity for various research applications, including RNA labeling, probing, and therapeutic development.
CAT: BRP-00621
MF: C52H64N5O11P
MF: 966.08
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: FKWHQFYMJVJQSH-ACHZJAKQSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(2-methoxyethoxy)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C52H64N5O11P/c1-36(2)57(37(3)4)69(66-29-15-28-53)68-46-45(35-65-52(40-18-13-10-14-19-40,41-20-24-43(61-7)25-21-41)42-22-26-44(62-8)27-23-42)67-50(47(46)64-33-32-63-31-30-60-6)56-34-38(5)48(55-51(56)59)54-49(58)39-16-11-9-12-17-39/h9-14,16-27,34,36-37,45-47,50H,15,29-33,35H2,1-8H3,(H,54,55,58,59)/t45-,46-,47-,50-,69?/m1/s1
Synonyms: 2'-MOEOE 5-Me-rC(Bz) amidite
