Nucleosides - RNA / BOC Sciences

Zeatin riboside

Description: A well-known, highly active stimulant of cell divisions in plant tissue cultures.

CAT: BRP-00146

CAS: 6025-53-2

MF: C15H21N5O5

MF: 351.36

Purity: 98%

Appearance: White to Pale Yellow Solid

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Storage: Store at -20°C (under dark)

Density: 1.65±0.1 g/cm3

Melting Point: 178-182°C

Boiling Point: 731.8±70.0°C at 760 mmHg

Application: Plant Growth Regulators

InChIKey: GOSWTRUMMSCNCW-HNNGNKQASA-N

Solubility: Soluble in acetic acid (50 mg/mL), DMSO (Slightly), Methanol (Slightly, Sonicated)

CanonicalSMILES: CC(=CCNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O)CO

IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(E)-4-hydroxy-3-methylbut-2-enyl]amino]purin-9-yl]oxolane-3,4-diol

InChI: InChI=1S/C15H21N5O5/c1-8(4-21)2-3-16-13-10-14(18-6-17-13)20(7-19-10)15-12(24)11(23)9(5-22)25-15/h2,6-7,9,11-12,15,21-24H,3-5H2,1H3,(H,16,17,18)/b8-2+/t9-,11-,12-,15-/m1/s1

Synonyms: Adenosine, N-[(2E)-4-hydroxy-3-methyl-2-buten-1-yl]-; Adenosine, N-(4-hydroxy-3-methyl-2-butenyl)-, (E)-; Adenosine, N-[(2E)-4-hydroxy-3-methyl-2-butenyl]-; N-[(2E)-4-Hydroxy-3-methyl-2-buten-1-yl]adenosine; 6-[(E)-4-Hydroxy-3-methylbut-2-enylamino]-9-β-D-ribofuranosylpurine; 6-(4-Hydroxy-3-methyl-trans-2-butenylamino)-9-β-D-ribofuranosylpurine; 9-Ribosyl-trans-zeatin; 9-β-D-Ribofuranosylzeatin; MB 804; N6-(4-Hydroxy-3-methylbut-2-trans-enyl)adenosine; N6-(trans-4-Hydroxy-3-methylbut-2-enyl)adenosine; Ribosyl-trans-zeatin; Ribosylzeatin; trans-Zeatin 9-riboside; trans-Zeatin riboside; Zeatin 9-riboside; Zeatin 9-β-ribonucleoside; Zeatin ribonucleoside; Zeatin-9-β-D-ribofuranoside

Related CAS: 7286-65-9 (Deleted CAS) ; 50816-91-6 (Deleted CAS)

2'-O-tert-Butyldimethylsilyl-5-methyluridine

Description: 2'-O-tert-Butyldimethylsilyl-5-methyluridine standing as an essential entity wielded within the biomedical realm to orchestrate the research and development of nucleoside analogs. Rendering itself instrumental in crafting antiviral medications and providing a foundational cornerstone for tackling an assortment of viral afflictions, this compound exhibiting indomitably consequential characteristics that have propelled it towards the forefront of pharmaceutical research and development.

CAT: BRP-00147

CAS: 922508-26-7

MF: C16H28N2O6Si

MF: 372.49

Purity: ≥97% by HPLC

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Density: 1.23±0.1 g/cm3

Melting Point: 97-100 °C

InChIKey: PWAAFDSCYLYFMA-HKUMRIAESA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O[Si](C)(C)C(C)(C)C

IUPAC Name: 1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C16H28N2O6Si/c1-9-7-18(15(22)17-13(9)21)14-12(11(20)10(8-19)23-14)24-25(5,6)16(2,3)4/h7,10-12,14,19-20H,8H2,1-6H3,(H,17,21,22)/t10-,11-,12-,14-/m1/s1

Synonyms: 2'-TBDMS-5-Me-rU; 2'-O-[(1,1-Dimethylethyl)dimethylsilyl]-5-methyluridine; 2'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-5-methyluridine

2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine

Description: 2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine is a complex and multifunctional nucleoside analog extensively used in pharmaceutical applications to counter cytidine-sensitive viruses, including hepatitis B and C infections. The compound serves as a significant precursor for the synthesis of modified RNA-based therapies that have promising curative effects for genetic disorders and cancer treatments. Its diverse chemical properties make it an essential and indispensable agent for investigating various antiviral mechanisms that could pave the way for novel and innovative drug discovery.

CAT: BRP-00148

CAS: 185398-21-4

MF: C22H31N3O6Si

MF: 461.58

Purity: ≥97% by HPLC

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Density: 1.161±0.06 g/cm3

Boiling Point: 608.6±65.0 °C at 760 mmHg

InChIKey: VVBIKBICTSKFIO-DLVXIWMQSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)CO)O

IUPAC Name: N-[1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C22H31N3O6Si/c1-22(2,3)32(4,5)31-18-17(27)15(13-26)30-20(18)25-12-11-16(24-21(25)29)23-19(28)14-9-7-6-8-10-14/h6-12,15,17-18,20,26-27H,13H2,1-5H3,(H,23,24,28,29)/t15-,17-,18-,20-/m1/s1

Synonyms: 2'-TBDMS-Bz-rC; N4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine; N-Benzoyl-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine; Cytidine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-

2'-O-tert-Butyldimethylsilyluridine

Description: 2'-O-tert-Butyldimethylsilyluridine, an indispensable compound within the biomedical field, serves as a pivotal synthetic intermediate for nucleoside analogues. Notably, it assumes a vital function in the production of antiviral medications, specifically targeting the eradication of hepatitis B and C viral infections. Given its distinct structural and inherent characteristics, this compound assumes an indispensable role in the intricate processes of drug discovery and development.

CAT: BRP-00149

CAS: 54925-71-2

MF: C15H26N2O6Si

MF: 358.46

Purity: ≥97% by HPLC

Appearance: White to Off-white Crystalline Powder

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Storage: Store at RT

Density: 1.25±0.1 g/cm3

Melting Point: 192-194 °C

InChIKey: AYQZFVZTNUOLCQ-OJAKKHQRSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=CC(=O)NC2=O)CO)O

IUPAC Name: 1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C15H26N2O6Si/c1-15(2,3)24(4,5)23-12-11(20)9(8-18)22-13(12)17-7-6-10(19)16-14(17)21/h6-7,9,11-13,18,20H,8H2,1-5H3,(H,16,19,21)/t9-,11-,12-,13-/m1/s1

Synonyms: 2'-TBDMS-rU; Uridine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 2'-O-[Dimethyl(2-methyl-2-propanyl)silyl]uridine; 2'-O-[(1,1-Dimethylethyl)dimethylsilyl]uridine

N4-Acetyl-5'-O-tert-butyldimethylsilylcytidine

Description: N4-Acetyl-5'-O-tert-butyldimethylsilylcytidine is utilized as a key component for research and development related to antiviral drugs. It plays a role in the research of various viral infections, supporting the design and development of innovative antiviral therapies.

CAT: BRP-00150

CAS: 119794-51-3

MF: C17H29N3O6Si

MF: 399.51

Purity: 97%

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Density: 1.28±0.1 g/cm3

InChIKey: WVZROKQICURVJD-NMFUWQPSSA-N

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO[Si](C)(C)C(C)(C)C)O)O

IUPAC Name: N-[1-[(2R,3R,4S,5R)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-3,4-dihydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C17H29N3O6Si/c1-10(21)18-12-7-8-20(16(24)19-12)15-14(23)13(22)11(26-15)9-25-27(5,6)17(2,3)4/h7-8,11,13-15,22-23H,9H2,1-6H3,(H,18,19,21,24)/t11-,13-,14-,15-/m1/s1

Synonyms: 5'-TBDMS-Ac-rC; Cytidine, N-acetyl-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-; N-Acetyl-5'-O-[(1,1-dimethylethyl)dimethylsilyl]cytidine; 5'-O-tert-Butyldimethylsilyl-N4-acetyl-cytidine

N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine

Description: N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine, a remarkable and potent biomedicine, stands as a beacon of hope in the fight against viral infections, including hepatitis C and HIV. Through meticulous investigation, scientists have unveiled its profound antiviral prowess, effectively hindering viral replication. By skillfully targeting specific viral enzymes, it adeptly curtails viral load while bolstering the body's immune response.

CAT: BRP-00151

CAS: 69504-07-0

MF: C23H31N5O5Si

MF: 485.61

Purity: ≥97% by HPLC

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Density: 1.33±0.1 g/cm3 (Predicted)

InChIKey: XZQPQOSSEMTXOW-UVLLPENVSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O

IUPAC Name: N-[9-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C23H31N5O5Si/c1-23(2,3)34(4,5)33-18-17(30)15(11-29)32-22(18)28-13-26-16-19(24-12-25-20(16)28)27-21(31)14-9-7-6-8-10-14/h6-10,12-13,15,17-18,22,29-30H,11H2,1-5H3,(H,24,25,27,31)/t15-,17-,18-,22-/m1/s1

Synonyms: 2'-TBDMS-Bz-rA; 2'-O-tert-butyldimethylsilyl-N6-Benzoyl-adenosine; N-Benzoyl-2'-O-(tert-butyldimethylsilyl)adenosine; Adenosine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; N-Benzoyl-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine; N-Benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine; 2'-O-tert-Butyldimethylsilyl-N-benzoyladenosine; N6-Benzoyl-2'-O-(tert-butyldimethylsilyl)adenosine

6-Chloro-9-(β-D-ribofuranosyl)purine

Description: 6-Chloro-9-(β-D-ribofuranosyl)purine, a potent pharmaceutical compound, finds its application in combating chemotherapy-induced emesis and radiation sickness. Its remarkable antiviral activity thwarts diverse viral infections by effectively impeding viral replication. Additionally, this product serves as an invaluable nucleoside analog for cutting-edge research pertaining to nucleic acids and nucleotide metabolism.

CAT: BRP-00152

CAS: 2004-06-0

MF: C10H11ClN4O4

MF: 286.67

Purity: 97%

Appearance: Yellow to Green Powder

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Storage: Store at -20°C

Density: 2.03±0.1 g/cm3

Melting Point: 161-163°C

Boiling Point: 614.8±65.0 °C at 760 mmHg

InChIKey: XHRJGHCQQPETRH-KQYNXXCUSA-N

CanonicalSMILES: C1=NC2=C(C(=N1)Cl)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: (2R,3R,4S,5R)-2-(6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H11ClN4O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2/t4-,6-,7-,10-/m1/s1

Synonyms: 6-Chloropurine riboside; Chloropurine riboside; 6-Chloro-9-ribofuranosyl-9H-purine; 6-Chloropurine ribonucleoside

5-Methylcyclocytidine hydrochlorine

Description: 5-Methylcyclocytidine hydrochlorine, a nucleoside analogue of cytidine, exhibits profound biomedical implications in combating specific ailments. Its inherent capability to impede nucleotide synthesis and viral replication positions it as a prospective anticancer and antiviral agent. However, elucidating its complete therapeutic prowess necessitates further comprehensive investigation, thus underscoring the importance of conducting extensive scientific research.

CAT: BRP-00153

CAS: 51391-96-9

MF: C10H14ClN3O4

MF: 275.69

Purity: ≥95%

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Storage: Store at 2-8°C

Density: 1.88±0.1 g/cm3

Boiling Point: 422.4±55.0 °C at 760 mmHg

InChIKey: NTLAKIOXMNOMIC-HSMTUSTJSA-N

CanonicalSMILES: CC1=CN2C3C(C(C(O3)CO)O)OC2=NC1=N.Cl

IUPAC Name: (2R,4R,5R,6S)-4-(hydroxymethyl)-10-imino-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-5-ol;hydrochloride

InChI: InChI=1S/C10H13N3O4.ClH/c1-4-2-13-9-7(6(15)5(3-14)16-9)17-10(13)12-8(4)11;/h2,5-7,9,11,14-15H,3H2,1H3;1H/t5-,6-,7+,9-;/m1./s1

Synonyms: O-2,3'-Anhydro-5-methylcytidine hydrochloride; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-7-methyl-, monohydrochloride, [2R-(2α,3β,3aβ,9aβ)]-; (2R,3R,3aS,9aR)-2-(Hydroxymethyl)-6-imino-7-methyl-3,3a,6,9a-tetrahydro-2H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3-ol Hydrochloride; CMC.HCl

Related CAS: 763867-43-2 (free base)

N2-DMF-2'-O-methylguanosine

Description: N2-DMF-2'-O-methylguanosine, an indispensable biomedical resource, showcases remarkable efficacy in combating targeted illnesses. Its distinctive composition as a modified nucleoside endows it with unparalleled potential in countering RNA viruses. Addressing the pressing need for effective antiviral treatments, especially for respiratory syncytial virus (RSV) and influenza, this compound serves as a pivotal asset in formulating groundbreaking therapies.

CAT: BRP-00154

CAS: 183737-04-4

MF: C14H20N6O5

MF: 352.35

Purity: ≥97% by HPLC

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Density: 1.6±0.1 g/cm3

InChIKey: KDQQTCFKBCWYFL-QYVSTXNMSA-N

CanonicalSMILES: CN(C)C=NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)OC

IUPAC Name: N'-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide

InChI: InChI=1S/C14H20N6O5/c1-19(2)5-16-14-17-11-8(12(23)18-14)15-6-20(11)13-10(24-3)9(22)7(4-21)25-13/h5-7,9-10,13,21-22H,4H2,1-3H3,(H,17,18,23)/t7-,9-,10-,13-/m1/s1

Synonyms: DMF-2'-OMe-G; N2-[(dimethylamino)methylidene]-2'-O-methyl-D-guanosine; N2-DMF-2'-O-methyl-D-guanosine; N2-DMF-2'-OMe-rG; Guanosine, N-[(dimethylamino)methylene]-2'-O-methyl-; N-(Dimethylaminomethylene)-2'-O-methylguanosine

N4-Benzoyl-2'-O-methylcytidine

Description: N4-Benzoyl-2'-O-methylcytidine, a highly effective biomedicine, emerges as a paramount intervention for combating RNA viruses that induce viral infections. Renowned for its antiviral attributes, this groundbreaking product has garnered substantial scientific attention. Notably, its exceptional efficacy in addressing afflictions such as influenza and hepatitis has been extensively documented.

CAT: BRP-00155

CAS: 52571-45-6

MF: C17H19N3O6

MF: 361.35

Purity: ≥95%

Appearance: White to Pale Yellow Powder

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Storage: Store at 2-8°C

Density: 1.49±0.1 g/cm3 (Predicted)

Melting Point: 174-175°C

InChIKey: LIZIIHWLABYQKD-XKVFNRALSA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)CO)O

IUPAC Name: N-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C17H19N3O6/c1-25-14-13(22)11(9-21)26-16(14)20-8-7-12(19-17(20)24)18-15(23)10-5-3-2-4-6-10/h2-8,11,13-14,16,21-22H,9H2,1H3,(H,18,19,23,24)/t11-,13-,14-,16-/m1/s1

Synonyms: N-Benzoyl-2'-O-methylcytidine; NSC 371910; N-(1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide; N4-Bz-2'-OMe-C; 2'-OMe-C(Bz)

N2-DMF-rG

Description: N2-DMF-rG, a modified RNA nucleoside, is widely applied in the biomedical industry as a disease-targeting oligonucleotide precursor with remarkable curative potential against various viral and genetic diseases. Leveraging its high specificity and beneficial metabolism, N2-DMF-rG empowers the development of superior therapeutic oligonucleotides, fundamentally free from off-target effects, enabling stable and extended pharmacokinetics, in turn promising an efficacious disease intervention paradigm.

CAT: BRP-00156

CAS: 17331-16-7

MF: C13H18N6O5

MF: 338.32

Purity: ≥95% by HPLC

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Density: 1.77±0.1 g/cm3

Melting Point: 245-246 °C

Boiling Point: 708.5±70.0°C at 760 mmHg

InChIKey: WDAVDBAMSKZBEN-PZYHSTABSA-N

CanonicalSMILES: CN(C)C=NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: N'-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide

InChI: InChI=1S/C13H18N6O5/c1-18(2)4-15-13-16-10-7(11(23)17-13)14-5-19(10)12-9(22)8(21)6(3-20)24-12/h4-6,8-9,12,20-22H,3H2,1-2H3,(H,16,17,23)/b15-4+/t6-,8-,9-,12-/m1/s1

Synonyms: N'-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide; Formamidine, N'-(1,6-dihydro-6-oxo-9-β-D-ribofuranosyl-9H-purin-2-yl)-N,N-dimethyl-; N-[(Dimethylamino)methylene]guanosine; rG(dmf); N2-Dimethylaminomethylene-rG

N4-Benzoylcytidine

Description: A useful building block for oligoribonucleotide synthesis.

CAT: BRP-00157

CAS: 13089-48-0

MF: C16H17N3O6

MF: 347.32

Purity: ≥97% by HPLC

Appearance: White to Off-white Powder

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Storage: Store at 2-8°C

Density: 1.59 g/cm3

Melting Point: 218-221°C

InChIKey: BNXBRFDWSPXODM-BPGGGUHBSA-N

Solubility: Soluble in DMSO, Methanol

CanonicalSMILES: C1=CC=C(C=C1)C(=O)NC2=NC(=O)N(C=C2)C3C(C(C(O3)CO)O)O

IUPAC Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C16H17N3O6/c20-8-10-12(21)13(22)15(25-10)19-7-6-11(18-16(19)24)17-14(23)9-4-2-1-3-5-9/h1-7,10,12-13,15,20-22H,8H2,(H,17,18,23,24)/t10-,12-,13-,15-/m1/s1

Synonyms: N-Benzoylcytidine; N-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide; 4-N-benzoyl cytidine; N6-Benzoylcytidine; NSC 242979; ribo Cytidine (n-bz)

N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine

Description: N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine, an influential therapeutic agent, stands as a formidable solution for combating viral infections such as hepatitis C and HIV. By harmoniously intertwining the antiviral attributes of cytidine with the defensive capabilities endowed by tert-butyldimethylsilyl and DMT groups, this compound markedly amplifies drug sturdiness and effectiveness.

CAT: BRP-00158

CAS: 81246-78-8

MF: C43H49N3O8Si

MF: 763.95

Purity: ≥98% by HPLC

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Density: 1.19±0.1 g/cm3 at 20°C

InChIKey: ADAGVSVPBZZOKW-PKGPUZNISA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1O)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

IUPAC Name: N-[1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C43H49N3O8Si/c1-42(2,3)55(6,7)54-38-35(53-40(37(38)47)46-27-26-36(45-41(46)49)44-39(48)29-14-10-8-11-15-29)28-52-43(30-16-12-9-13-17-30,31-18-22-33(50-4)23-19-31)32-20-24-34(51-5)25-21-32/h8-27,35,37-38,40,47H,28H2,1-7H3,(H,44,45,48,49)/t35-,37-,38-,40-/m1/s1

Synonyms: 5'-DMT-3'-tBDSilyl Cytidine (n-bz); 5'-DMT-3'-TBDMS-Bz-rC; N4-Benzyl-3'-O-t-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)cytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-Cytidine; N4-Bz-5'-O-DMT-3'-O-TBDMS-cytidine

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine

Description: It is used for special nucleoside or RNA modification.

CAT: BRP-00159

CAS: 81246-81-3

MF: C36H44N2O8Si

MF: 660.83

Purity: ≥95%

Appearance: White Solid

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Density: 1.3±0.1 g/cm3

InChIKey: ZATGYRPVDYINRF-WXQJYUTRSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1O)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: 1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C36H44N2O8Si/c1-35(2,3)47(6,7)46-32-29(45-33(31(32)40)38-22-21-30(39)37-34(38)41)23-44-36(24-11-9-8-10-12-24,25-13-17-27(42-4)18-14-25)26-15-19-28(43-5)20-16-26/h8-22,29,31-33,40H,23H2,1-7H3,(H,37,39,41)/t29-,31-,32-,33-/m1/s1

Synonyms: 5'-DMT-3'-tBDSilyl Uridine; 5'-O-DMT-3'-O-TBDMS uridine; 5'-O-(4,4'-Dimethoxytrityl)-3'-O-t-butyldimethylsilyl uridine; 3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)uridine; 1-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-3-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]uridine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine

Description: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine, an imperative compound employed in the field of biomedicine, exhibits noteworthy significance in the process of synthesizing nucleic acids for genetic investigations. Through the modification of nucleotides, this compound facilitates precise administration of therapeutic drugs and gene therapy. Expanding its utility, it finds applications in addressing a myriad of ailments including cancer, viral infections, and genetic disorders, thereby serving as an indispensable instrument in the realm of biomedical research.

CAT: BRP-00160

CAS: 81256-89-5

MF: C41H51N5O8Si

MF: 769.96

Purity: 97%

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Density: 1.25±0.1 g/cm3(Predicted)

InChIKey: XAIQBZNFPUNWMQ-CJEGOSRCSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O[Si](C)(C)C(C)(C)C)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C41H51N5O8Si/c1-25(2)36(48)44-39-43-35-32(37(49)45-39)42-24-46(35)38-33(47)34(54-55(8,9)40(3,4)5)31(53-38)23-52-41(26-13-11-10-12-14-26,27-15-19-29(50-6)20-16-27)28-17-21-30(51-7)22-18-28/h10-22,24-25,31,33-34,38,47H,23H2,1-9H3,(H2,43,44,45,48,49)/t31-,33-,34-,38-/m1/s1

Synonyms: 5'-DMT-3'-tBDSilyl Guanosine (n-ibu); 5'-DMT-3'-TBDMS-ibu-rG; N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-3'-O-tert-butyldimethylsilyl guanosine

N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine

Description: N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a cutting-edge and technologically advanced biomedical compound aiding in studying an extensive array of debilitating diseases.

CAT: BRP-00161

CAS: 123956-65-0

MF: C38H47N3O8Si

MF: 701.88

Purity: 98%

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Storage: Store at 2-8°C

Density: 1.19±0.1 g/cm3 (Predicted)

InChIKey: RWIUJRXXJFJUFX-HYGOWAQNSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O[Si](C)(C)C(C)(C)C)O

IUPAC Name: N-[1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C38H47N3O8Si/c1-25(42)39-32-22-23-41(36(44)40-32)35-33(43)34(49-50(7,8)37(2,3)4)31(48-35)24-47-38(26-12-10-9-11-13-26,27-14-18-29(45-5)19-15-27)28-16-20-30(46-6)21-17-28/h9-23,31,33-35,43H,24H2,1-8H3,(H,39,40,42,44)/t31-,33-,34-,35-/m1/s1

Synonyms: 5'-DMT-3'-TBDMS-Ac-rC; N-(1-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide; 3'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N4-acetyl cytidine; 3'-O-TBDMS-5'-O-DMT-N4-Ac cytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]cytidine; 5'-DMT-3'-TBDMS-C(Ac)

N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine

Description: It is used for nucleoside modification, amidite and nucleic acid synthesis.

CAT: BRP-00162

CAS: 81256-88-4

MF: C44H49N5O7Si

MF: 787.97

Purity: 96%

Appearance: White to Off-white Powder

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Storage: Store at 2-8°C

Density: 1.2±0.1 g/cm3

InChIKey: QNPRMZLAAWKAPQ-GNECSJIWSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1O)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

IUPAC Name: N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C44H49N5O7Si/c1-43(2,3)57(6,7)56-38-35(55-42(37(38)50)49-28-47-36-39(45-27-46-40(36)49)48-41(51)29-14-10-8-11-15-29)26-54-44(30-16-12-9-13-17-30,31-18-22-33(52-4)23-19-31)32-20-24-34(53-5)25-21-32/h8-25,27-28,35,37-38,42,50H,26H2,1-7H3,(H,45,46,48,51)/t35-,37-,38-,42-/m1/s1

Synonyms: 5'-DMT-3'-tBDSilyl Adenosine (n-bz); N6-benzoyl-5'-O-DMT-3'-O-TBDMS-adenosine; N6-benzoyl-3'-O-t-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-adenosine; 5'-DMT-3'-TBDMS-Bz-rA; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine

5'-O-DMT-2'-O-methyl-5-methyluridine

Description: 5'-O-DMT-2'-O-methyl-5-methyluridine is a modified nucleoside molecule that contains a 5'-O-dimethoxytrityl (DMT) group on the 5' carbon, a 2'-O-methyl group on the 2' carbon, and a methyl group on the 5th carbon of the uracil base. This modification is commonly used in nucleic acid synthesis and research to protect and manipulate nucleosides for various applications.

CAT: BRP-00163

CAS: 153631-19-7

MF: C32H34N2O8

MF: 574.62

Purity: ≥97% by HPLC

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Density: 1.33±0.1 g/cm3 (Predicted)

InChIKey: VFLOXJCZWDDILQ-NODMTMHWSA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OC

IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C32H34N2O8/c1-20-18-34(31(37)33-29(20)36)30-28(40-4)27(35)26(42-30)19-41-32(21-8-6-5-7-9-21,22-10-14-24(38-2)15-11-22)23-12-16-25(39-3)17-13-23/h5-18,26-28,30,35H,19H2,1-4H3,(H,33,36,37)/t26-,27-,28-,30-/m1/s1

Synonyms: 5'-DMT-5-Me-2'-OMe-U; DMT-5-Me-2'-OMe-U; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-methyl-2'-O-methyl-; 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-methyl-2'-O-methyl-Uridine; 5'-O-(Dimethoxytrityl)-2'-O-methyl-5-methyluridine; 5-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-uridine

N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine

Description: N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a valuable compound extensively used in the biomedical industry acting as a key intermediate for the synthesis of nucleotides and nucleosides. This product finds application in the development of antiviral drugs targeting various diseases caused by viral infections.

CAT: BRP-00165

CAS: 81256-87-3

MF: C43H49N3O8Si

MF: 763.95

Purity: ≥98% by HPLC

Appearance: White to Light Yellow Powder to Crystalline Powder

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Storage: Store at -20°C

Density: 1.2±0.1 g/cm3

InChIKey: AOXWVTIMEGOVNF-PKGPUZNISA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C43H49N3O8Si/c1-42(2,3)55(6,7)54-38-37(47)35(53-40(38)46-27-26-36(45-41(46)49)44-39(48)29-14-10-8-11-15-29)28-52-43(30-16-12-9-13-17-30,31-18-22-33(50-4)23-19-31)32-20-24-34(51-5)25-21-32/h8-27,35,37-38,40,47H,28H2,1-7H3,(H,44,45,48,49)/t35-,37-,38-,40-/m1/s1

Synonyms: 5'-DMT-2'-tBDSilyl Cytidine (n-bz); 5'-DMT-2'-TBDMS-Bz-rC; 5'-O-DMT-2'-O-TBDMS-N-Bz-Cytidine; N-(1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-N-benzoylcytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[tert-butyl(dimethyl)silyl]cytidine; N4-Benzoyl-2'-O-(tert-butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)cytidine

5'-O-DMT-N2-DMF-guanosine

Description: 5'-O-DMT-N2-DMF-guanosine, a remarkably powerful nucleoside analog, assumes a crucial role in the realm of biomedicine in combatting select malignancies. Its extraordinary molecular architecture endows it with the ability to impede the proliferation of neoplastic cells via targeted interference with distinct signaling cascades. By virtue of this distinct attribute, this compound holds potential for augmented therapeutic efficacy and mitigated untoward ramifications when used concomitantly with other chemotherapeutic agents.

CAT: BRP-00166

CAS: 126922-60-9

MF: C34H36N6O7

MF: 640.69

Purity: ≥98% by HPLC

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Density: 1.4±0.1 g/cm3

InChIKey: FWBIVABFLXJWQH-NXKHUQPWSA-N

CanonicalSMILES: CN(C)C=NC1=NC(=O)C2C(=N1)N(C=N2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)O

IUPAC Name: N'-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-6-oxo-5H-purin-2-yl]-N,N-dimethylmethanimidamide

InChI: InChI=1S/C34H36N6O7/c1-39(2)19-36-33-37-30-27(31(43)38-33)35-20-40(30)32-29(42)28(41)26(47-32)18-46-34(21-8-6-5-7-9-21,22-10-14-24(44-3)15-11-22)23-12-16-25(45-4)17-13-23/h5-17,19-20,26-29,32,41-42H,18H2,1-4H3/b36-19+/t26-,27?,28-,29-,32-/m1/s1

Synonyms: 5'-DMT-DMF-rG; 5'-O-(4,4'-Dimethoxytrityl)-N2-DMF-Guanosine; 5'-O-DMT-N2-DMF-rG; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-N-[(dimethylamino)methylene]guanosine; N'-(9-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide; 5'-O-DMT-G(DMF)