Nucleosides

2'-Modified Nucleosides
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3'-Modified Nucleosides
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5'-Modified Nucleosides
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Anhydro-Nucleosides
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Arabinonucleosides
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Base Protected Nucleosides
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5'-O-(4,4'-Dimethoxytrityl)-2,2'-anhydro-D-uridine

Description: 5'-O-(4,4'-Dimethoxytrityl)-2,2'-anhydro-D-uridine, a multifaceted compound extensively employed in the field of biomedicine, exhibits utmost significance. Its pivotal involvement lies within the synthesis of pharmaceutical nucleoside analogs, specifically for combating viral infections such as HIV and hepatitis.
CAT: BRP-00116
CAS: 173170-12-2
Molecular Formula: C30H28N2O7
Molecular Weight: 528.55
Purity: ≥95%
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Density: 1.4±0.1 g/cm3
Boiling Point: 688.2±65.0°C at 760 mmHg
InChIKey: OEIRLWHCGAICDW-AOGFTHLWSA-N
CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C5C(O4)N6C=CC(=O)N=C6O5)O
IUPAC Name: (2R,4R,5R,6S)-4-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-hydroxy-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one
InChI: InChI=1S/C30H28N2O7/c1-35-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(36-2)15-11-21)37-18-24-26(34)27-28(38-24)32-17-16-25(33)31-29(32)39-27/h3-17,24,26-28,34H,18H2,1-2H3/t24-,26-,27+,28-/m1/s1
Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2,2'-anhydro-b-D-arabinofuranosyluracil; (2R,3R,3aS,9aR)-2-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-hydroxy-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one; 2,2'-Anhydro-5'-O-DMT-uridine; 2,2'-Anhydro-5'-O-(4,4'-dimethoxytrityl)uridine; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-2,3,3a,9a-tetrahydro-3-hydroxy-, [2R-(2α,3β,3aβ,9aβ)]-

S-Adenosyl-L-Methionine

Description: S-adenosyl-l-methionine (SAMe) is a naturally occurring substance which is a major source of methyl groups in the brain. The efficacy of SAMe in treating depressive syndromes and disorders is superior to that of placebo and comparable to that of standard tricyclic antidepressants. Since SAMe is a naturally occurring compound with relatively few side effects, it is a potentially important treatment for depression. S-adenosylmethionine (SAMe) is a dietary supplement used in the management of osteoarthritis (OA) symptoms. Studies evaluating SAMe in the management of OA have been limited to Non Steroidal Anti-inflammatory Drugs (NSAIDs) for comparison. The present study compares the effectiveness of SAMe to a cyclooxygenase-2 (COX-2) inhibitor (celecoxib) for pain control, functional improvement and to decrease side effects in people with osteoarthritis of the knee. It also acts as a PDE4B inhibitor.
Nutritional supplement in health care products.
CAT: BRP-00119
CAS: 29908-03-0
Molecular Formula: C15H22N6O5S
Molecular Weight: 398.44
Purity: 98%
Appearance: White to Off-White Powder
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Storage: Store at -20 °C
Application: Ingredient of health care products.
InChIKey: MEFKEPWMEQBLKI-AIRLBKTGSA-N
CanonicalSMILES: C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O
IUPAC Name: (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate
InChI: InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/t7-,8+,10+,11+,14+,27?/m0/s1
Synonyms: S-Adenosylmethionine; Ademetionine; AdoMet; MSI-195; MSI 195; MSI195; SAMe; S-Adenosyl-L-methionine; L-S-Adenosylmethionine; S-Adenosyl methionine; Adenosine, 5'-[(L-3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxy-, hydroxide, inner salt; Active methionine; Adenosyl-L-methionine; Donamet; S Amet; SAH (S-Adenosylmethionine); SAM; SAM (S-Adenosyl methionine); Transmetil

5-Fluoro Cytidine

Description: 5-Fluoro Cytidine is a modified nucleoside that contains a fluorine atom at the 5th position of the cytidine molecule. It is a synthetic compound that has shown potential therapeutic effects in the treatment of certain types of cancer. 5-Fluoro Cytidine works by disrupting the process of RNA replication and inhibiting cell growth. It is currently being studied in clinical trials for its anti-cancer properties. 5-Fluoropyrimidine nucleotides as RNA structure probe using 19F-NMR spectroscopy.
CAT: BRP-00127
CAS: 2341-22-2
Molecular Formula: C9H12FN3O5
Molecular Weight: 261.21
Purity: ≥95%
Appearance: White to Off-white Solid
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Storage: Store at -20°C
Density: 1.98±0.1 g/cm3 (Predicted)
Melting Point: 183-185°C
Boiling Point: 511.4±60.0°C (Predicted)
InChIKey: STRZQWQNZQMHQR-UAKXSSHOSA-N
Solubility: Soluble in Methanol (Slightly, Heated), Water (Slightly)
CanonicalSMILES: C1=C(C(=NC(=O)N1C2C(C(C(O2)CO)O)O)N)F
IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidin-2-one
InChI: InChI=1S/C9H12FN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1
Synonyms: 5-Fluorocytidine; 5F-C; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one; 4-Amino-5-fluor-1-(β-D-ribofuranosyl)pyrimidin-2(1H)-one; L-β-Ribofuranosyl-5-fluoro-cytosine

3-Deazaadenosine

Description: 3-Deazaadenosine (3-DZA) is an inhibitor of SAH hydrolase (Ki = 3.9 μM). 3-Deazaadenosine is a modified form of the nucleoside adenosine, where a nitrogen atom in the purine ring is replaced with a carbon atom. This modification results in the compound lacking the ability to form hydrogen bonds with complementary nucleotides, making it useful in studying the role of hydrogen bonding in nucleic acid structure and function. 3-Deazaadenosine has been investigated for its potential therapeutic applications, such as in the treatment of viral infections and cancer. It is also used as a biochemical tool in research to study RNA interactions and enzymatic mechanisms.
CAT: BRP-00145
CAS: 6736-58-9
Molecular Formula: C11H14N4O4
Molecular Weight: 266.26
Purity: ≥97% by HPLC
Appearance: Crystalline Solid
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Storage: Store at -20°C
Density: 1.90±0.1 g/cm3 at 20°C, 760 Torr
Melting Point: 222-224°C
Boiling Point: 665.7±65.0°C (Predicted)
Flash Point: 356.4±34.3 °C
InChIKey: DBZQFUNLCALWDY-PNHWDRBUSA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)
CanonicalSMILES: C1=CN=C(C2=C1N(C=N2)C3C(C(C(O3)CO)O)O)N
IUPAC Name: (2R,3R,4S,5R)-2-(4-aminoimidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChI: InChI=1S/C11H14N4O4/c12-10-7-5(1-2-13-10)15(4-14-7)11-9(18)8(17)6(3-16)19-11/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13)/t6-,8-,9-,11-/m1/s1
Synonyms: Deaza-Ado; (2R,3R,4S,5R)-2-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 3-Deaza-rA; 1-(beta-D-ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine; 4-Amino-1-(β-D-ribofuranosyl)-1H-imidazo(4,5)-pyridine

Zeatin riboside

Description: A well-known, highly active stimulant of cell divisions in plant tissue cultures.
CAT: BRP-00146
CAS: 6025-53-2
Molecular Formula: C15H21N5O5
Molecular Weight: 351.36
Purity: 98%
Appearance: White to Pale Yellow Solid
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Storage: Store at -20°C (under dark)
Density: 1.65±0.1 g/cm3
Melting Point: 178-182°C
Boiling Point: 731.8±70.0°C at 760 mmHg
Application: Plant Growth Regulators
InChIKey: GOSWTRUMMSCNCW-HNNGNKQASA-N
Solubility: Soluble in acetic acid (50 mg/mL), DMSO (Slightly), Methanol (Slightly, Sonicated)
CanonicalSMILES: CC(=CCNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O)CO
IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(E)-4-hydroxy-3-methylbut-2-enyl]amino]purin-9-yl]oxolane-3,4-diol
InChI: InChI=1S/C15H21N5O5/c1-8(4-21)2-3-16-13-10-14(18-6-17-13)20(7-19-10)15-12(24)11(23)9(5-22)25-15/h2,6-7,9,11-12,15,21-24H,3-5H2,1H3,(H,16,17,18)/b8-2+/t9-,11-,12-,15-/m1/s1
Synonyms: Adenosine, N-[(2E)-4-hydroxy-3-methyl-2-buten-1-yl]-; Adenosine, N-(4-hydroxy-3-methyl-2-butenyl)-, (E)-; Adenosine, N-[(2E)-4-hydroxy-3-methyl-2-butenyl]-; N-[(2E)-4-Hydroxy-3-methyl-2-buten-1-yl]adenosine; 6-[(E)-4-Hydroxy-3-methylbut-2-enylamino]-9-β-D-ribofuranosylpurine; 6-(4-Hydroxy-3-methyl-trans-2-butenylamino)-9-β-D-ribofuranosylpurine; 9-Ribosyl-trans-zeatin; 9-β-D-Ribofuranosylzeatin; MB 804; N6-(4-Hydroxy-3-methylbut-2-trans-enyl)adenosine; N6-(trans-4-Hydroxy-3-methylbut-2-enyl)adenosine; Ribosyl-trans-zeatin; Ribosylzeatin; trans-Zeatin 9-riboside; trans-Zeatin riboside; Zeatin 9-riboside; Zeatin 9-β-ribonucleoside; Zeatin ribonucleoside; Zeatin-9-β-D-ribofuranoside
Related CAS: 7286-65-9 (Deleted CAS) ; 50816-91-6 (Deleted CAS)

2'-O-tert-Butyldimethylsilyl-5-methyluridine

Description: 2'-O-tert-Butyldimethylsilyl-5-methyluridine standing as an essential entity wielded within the biomedical realm to orchestrate the research and development of nucleoside analogs. Rendering itself instrumental in crafting antiviral medications and providing a foundational cornerstone for tackling an assortment of viral afflictions, this compound exhibiting indomitably consequential characteristics that have propelled it towards the forefront of pharmaceutical research and development.
CAT: BRP-00147
CAS: 922508-26-7
Molecular Formula: C16H28N2O6Si
Molecular Weight: 372.49
Purity: ≥97% by HPLC
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Density: 1.23±0.1 g/cm3
Melting Point: 97-100 °C
InChIKey: PWAAFDSCYLYFMA-HKUMRIAESA-N
CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O[Si](C)(C)C(C)(C)C
IUPAC Name: 1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
InChI: InChI=1S/C16H28N2O6Si/c1-9-7-18(15(22)17-13(9)21)14-12(11(20)10(8-19)23-14)24-25(5,6)16(2,3)4/h7,10-12,14,19-20H,8H2,1-6H3,(H,17,21,22)/t10-,11-,12-,14-/m1/s1
Synonyms: 2'-TBDMS-5-Me-rU; 2'-O-[(1,1-Dimethylethyl)dimethylsilyl]-5-methyluridine; 2'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-5-methyluridine

2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine

Description: 2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine is a complex and multifunctional nucleoside analog extensively used in pharmaceutical applications to counter cytidine-sensitive viruses, including hepatitis B and C infections. The compound serves as a significant precursor for the synthesis of modified RNA-based therapies that have promising curative effects for genetic disorders and cancer treatments. Its diverse chemical properties make it an essential and indispensable agent for investigating various antiviral mechanisms that could pave the way for novel and innovative drug discovery.
CAT: BRP-00148
CAS: 185398-21-4
Molecular Formula: C22H31N3O6Si
Molecular Weight: 461.58
Purity: ≥97% by HPLC
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Density: 1.161±0.06 g/cm3
Boiling Point: 608.6±65.0 °C at 760 mmHg
InChIKey: VVBIKBICTSKFIO-DLVXIWMQSA-N
CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)CO)O
IUPAC Name: N-[1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C22H31N3O6Si/c1-22(2,3)32(4,5)31-18-17(27)15(13-26)30-20(18)25-12-11-16(24-21(25)29)23-19(28)14-9-7-6-8-10-14/h6-12,15,17-18,20,26-27H,13H2,1-5H3,(H,23,24,28,29)/t15-,17-,18-,20-/m1/s1
Synonyms: 2'-TBDMS-Bz-rC; N4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine; N-Benzoyl-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine; Cytidine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-

2'-O-tert-Butyldimethylsilyluridine

Description: 2'-O-tert-Butyldimethylsilyluridine, an indispensable compound within the biomedical field, serves as a pivotal synthetic intermediate for nucleoside analogues. Notably, it assumes a vital function in the production of antiviral medications, specifically targeting the eradication of hepatitis B and C viral infections. Given its distinct structural and inherent characteristics, this compound assumes an indispensable role in the intricate processes of drug discovery and development.
CAT: BRP-00149
CAS: 54925-71-2
Molecular Formula: C15H26N2O6Si
Molecular Weight: 358.46
Purity: ≥97% by HPLC
Appearance: White to Off-white Crystalline Powder
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Storage: Store at RT
Density: 1.25±0.1 g/cm3
Melting Point: 192-194 °C
InChIKey: AYQZFVZTNUOLCQ-OJAKKHQRSA-N
CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=CC(=O)NC2=O)CO)O
IUPAC Name: 1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C15H26N2O6Si/c1-15(2,3)24(4,5)23-12-11(20)9(8-18)22-13(12)17-7-6-10(19)16-14(17)21/h6-7,9,11-13,18,20H,8H2,1-5H3,(H,16,19,21)/t9-,11-,12-,13-/m1/s1
Synonyms: 2'-TBDMS-rU; Uridine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 2'-O-[Dimethyl(2-methyl-2-propanyl)silyl]uridine; 2'-O-[(1,1-Dimethylethyl)dimethylsilyl]uridine

N4-Acetyl-5'-O-tert-butyldimethylsilylcytidine

Description: N4-Acetyl-5'-O-tert-butyldimethylsilylcytidine is utilized as a key component for research and development related to antiviral drugs. It plays a role in the research of various viral infections, supporting the design and development of innovative antiviral therapies.
CAT: BRP-00150
CAS: 119794-51-3
Molecular Formula: C17H29N3O6Si
Molecular Weight: 399.51
Purity: 97%
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Density: 1.28±0.1 g/cm3
InChIKey: WVZROKQICURVJD-NMFUWQPSSA-N
CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO[Si](C)(C)C(C)(C)C)O)O
IUPAC Name: N-[1-[(2R,3R,4S,5R)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-3,4-dihydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C17H29N3O6Si/c1-10(21)18-12-7-8-20(16(24)19-12)15-14(23)13(22)11(26-15)9-25-27(5,6)17(2,3)4/h7-8,11,13-15,22-23H,9H2,1-6H3,(H,18,19,21,24)/t11-,13-,14-,15-/m1/s1
Synonyms: 5'-TBDMS-Ac-rC; Cytidine, N-acetyl-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-; N-Acetyl-5'-O-[(1,1-dimethylethyl)dimethylsilyl]cytidine; 5'-O-tert-Butyldimethylsilyl-N4-acetyl-cytidine

N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine

Description: N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine, a remarkable and potent biomedicine, stands as a beacon of hope in the fight against viral infections, including hepatitis C and HIV. Through meticulous investigation, scientists have unveiled its profound antiviral prowess, effectively hindering viral replication. By skillfully targeting specific viral enzymes, it adeptly curtails viral load while bolstering the body's immune response.
CAT: BRP-00151
CAS: 69504-07-0
Molecular Formula: C23H31N5O5Si
Molecular Weight: 485.61
Purity: ≥97% by HPLC
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Density: 1.33±0.1 g/cm3 (Predicted)
InChIKey: XZQPQOSSEMTXOW-UVLLPENVSA-N
CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O
IUPAC Name: N-[9-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C23H31N5O5Si/c1-23(2,3)34(4,5)33-18-17(30)15(11-29)32-22(18)28-13-26-16-19(24-12-25-20(16)28)27-21(31)14-9-7-6-8-10-14/h6-10,12-13,15,17-18,22,29-30H,11H2,1-5H3,(H,24,25,27,31)/t15-,17-,18-,22-/m1/s1
Synonyms: 2'-TBDMS-Bz-rA; 2'-O-tert-butyldimethylsilyl-N6-Benzoyl-adenosine; N-Benzoyl-2'-O-(tert-butyldimethylsilyl)adenosine; Adenosine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; N-Benzoyl-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine; N-Benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine; 2'-O-tert-Butyldimethylsilyl-N-benzoyladenosine; N6-Benzoyl-2'-O-(tert-butyldimethylsilyl)adenosine

6-Chloro-9-(β-D-ribofuranosyl)purine

Description: 6-Chloro-9-(β-D-ribofuranosyl)purine, a potent pharmaceutical compound, finds its application in combating chemotherapy-induced emesis and radiation sickness. Its remarkable antiviral activity thwarts diverse viral infections by effectively impeding viral replication. Additionally, this product serves as an invaluable nucleoside analog for cutting-edge research pertaining to nucleic acids and nucleotide metabolism.
CAT: BRP-00152
CAS: 2004-06-0
Molecular Formula: C10H11ClN4O4
Molecular Weight: 286.67
Purity: 97%
Appearance: Yellow to Green Powder
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Storage: Store at -20°C
Density: 2.03±0.1 g/cm3
Melting Point: 161-163°C
Boiling Point: 614.8±65.0 °C at 760 mmHg
InChIKey: XHRJGHCQQPETRH-KQYNXXCUSA-N
CanonicalSMILES: C1=NC2=C(C(=N1)Cl)N=CN2C3C(C(C(O3)CO)O)O
IUPAC Name: (2R,3R,4S,5R)-2-(6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChI: InChI=1S/C10H11ClN4O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2/t4-,6-,7-,10-/m1/s1
Synonyms: 6-Chloropurine riboside; Chloropurine riboside; 6-Chloro-9-ribofuranosyl-9H-purine; 6-Chloropurine ribonucleoside

5-Methylcyclocytidine hydrochlorine

Description: 5-Methylcyclocytidine hydrochlorine, a nucleoside analogue of cytidine, exhibits profound biomedical implications in combating specific ailments. Its inherent capability to impede nucleotide synthesis and viral replication positions it as a prospective anticancer and antiviral agent. However, elucidating its complete therapeutic prowess necessitates further comprehensive investigation, thus underscoring the importance of conducting extensive scientific research.
CAT: BRP-00153
CAS: 51391-96-9
Molecular Formula: C10H14ClN3O4
Molecular Weight: 275.69
Purity: ≥95%
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Storage: Store at 2-8°C
Density: 1.88±0.1 g/cm3
Boiling Point: 422.4±55.0 °C at 760 mmHg
InChIKey: NTLAKIOXMNOMIC-HSMTUSTJSA-N
CanonicalSMILES: CC1=CN2C3C(C(C(O3)CO)O)OC2=NC1=N.Cl
IUPAC Name: (2R,4R,5R,6S)-4-(hydroxymethyl)-10-imino-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-5-ol;hydrochloride
InChI: InChI=1S/C10H13N3O4.ClH/c1-4-2-13-9-7(6(15)5(3-14)16-9)17-10(13)12-8(4)11;/h2,5-7,9,11,14-15H,3H2,1H3;1H/t5-,6-,7+,9-;/m1./s1
Synonyms: O-2,3'-Anhydro-5-methylcytidine hydrochloride; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-7-methyl-, monohydrochloride, [2R-(2α,3β,3aβ,9aβ)]-; (2R,3R,3aS,9aR)-2-(Hydroxymethyl)-6-imino-7-methyl-3,3a,6,9a-tetrahydro-2H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3-ol Hydrochloride; CMC.HCl
Related CAS: 763867-43-2 (free base)

N4-Benzoyl-2'-O-methylcytidine

Description: N4-Benzoyl-2'-O-methylcytidine, a highly effective biomedicine, emerges as a paramount intervention for combating RNA viruses that induce viral infections. Renowned for its antiviral attributes, this groundbreaking product has garnered substantial scientific attention. Notably, its exceptional efficacy in addressing afflictions such as influenza and hepatitis has been extensively documented.
CAT: BRP-00155
CAS: 52571-45-6
Molecular Formula: C17H19N3O6
Molecular Weight: 361.35
Purity: ≥95%
Appearance: White to Pale Yellow Powder
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Storage: Store at 2-8°C
Density: 1.49±0.1 g/cm3 (Predicted)
Melting Point: 174-175°C
InChIKey: LIZIIHWLABYQKD-XKVFNRALSA-N
CanonicalSMILES: COC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)CO)O
IUPAC Name: N-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C17H19N3O6/c1-25-14-13(22)11(9-21)26-16(14)20-8-7-12(19-17(20)24)18-15(23)10-5-3-2-4-6-10/h2-8,11,13-14,16,21-22H,9H2,1H3,(H,18,19,23,24)/t11-,13-,14-,16-/m1/s1
Synonyms: N-Benzoyl-2'-O-methylcytidine; NSC 371910; N-(1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide; N4-Bz-2'-OMe-C; 2'-OMe-C(Bz)

N2-DMF-rG

Description: N2-DMF-rG, a modified RNA nucleoside, is widely applied in the biomedical industry as a disease-targeting oligonucleotide precursor with remarkable curative potential against various viral and genetic diseases. Leveraging its high specificity and beneficial metabolism, N2-DMF-rG empowers the development of superior therapeutic oligonucleotides, fundamentally free from off-target effects, enabling stable and extended pharmacokinetics, in turn promising an efficacious disease intervention paradigm.
CAT: BRP-00156
CAS: 17331-16-7
Molecular Formula: C13H18N6O5
Molecular Weight: 338.32
Purity: ≥95% by HPLC
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Density: 1.77±0.1 g/cm3
Melting Point: 245-246 °C
Boiling Point: 708.5±70.0°C at 760 mmHg
InChIKey: WDAVDBAMSKZBEN-PZYHSTABSA-N
CanonicalSMILES: CN(C)C=NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)O
IUPAC Name: N'-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide
InChI: InChI=1S/C13H18N6O5/c1-18(2)4-15-13-16-10-7(11(23)17-13)14-5-19(10)12-9(22)8(21)6(3-20)24-12/h4-6,8-9,12,20-22H,3H2,1-2H3,(H,16,17,23)/b15-4+/t6-,8-,9-,12-/m1/s1
Synonyms: N'-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide; Formamidine, N'-(1,6-dihydro-6-oxo-9-β-D-ribofuranosyl-9H-purin-2-yl)-N,N-dimethyl-; N-[(Dimethylamino)methylene]guanosine; rG(dmf); N2-Dimethylaminomethylene-rG

N4-Benzoylcytidine

Description: A useful building block for oligoribonucleotide synthesis.
CAT: BRP-00157
CAS: 13089-48-0
Molecular Formula: C16H17N3O6
Molecular Weight: 347.32
Purity: ≥97% by HPLC
Appearance: White to Off-white Powder
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Storage: Store at 2-8°C
Density: 1.59 g/cm3
Melting Point: 218-221°C
InChIKey: BNXBRFDWSPXODM-BPGGGUHBSA-N
Solubility: Soluble in DMSO, Methanol
CanonicalSMILES: C1=CC=C(C=C1)C(=O)NC2=NC(=O)N(C=C2)C3C(C(C(O3)CO)O)O
IUPAC Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C16H17N3O6/c20-8-10-12(21)13(22)15(25-10)19-7-6-11(18-16(19)24)17-14(23)9-4-2-1-3-5-9/h1-7,10,12-13,15,20-22H,8H2,(H,17,18,23,24)/t10-,12-,13-,15-/m1/s1
Synonyms: N-Benzoylcytidine; N-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide; 4-N-benzoyl cytidine; N6-Benzoylcytidine; NSC 242979; ribo Cytidine (n-bz)

N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine

Description: N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine, an influential therapeutic agent, stands as a formidable solution for combating viral infections such as hepatitis C and HIV. By harmoniously intertwining the antiviral attributes of cytidine with the defensive capabilities endowed by tert-butyldimethylsilyl and DMT groups, this compound markedly amplifies drug sturdiness and effectiveness.
CAT: BRP-00158
CAS: 81246-78-8
Molecular Formula: C43H49N3O8Si
Molecular Weight: 763.95
Purity: ≥98% by HPLC
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Density: 1.19±0.1 g/cm3 at 20°C
InChIKey: ADAGVSVPBZZOKW-PKGPUZNISA-N
CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1O)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC
IUPAC Name: N-[1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C43H49N3O8Si/c1-42(2,3)55(6,7)54-38-35(53-40(37(38)47)46-27-26-36(45-41(46)49)44-39(48)29-14-10-8-11-15-29)28-52-43(30-16-12-9-13-17-30,31-18-22-33(50-4)23-19-31)32-20-24-34(51-5)25-21-32/h8-27,35,37-38,40,47H,28H2,1-7H3,(H,44,45,48,49)/t35-,37-,38-,40-/m1/s1
Synonyms: 5'-DMT-3'-tBDSilyl Cytidine (n-bz); 5'-DMT-3'-TBDMS-Bz-rC; N4-Benzyl-3'-O-t-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)cytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-Cytidine; N4-Bz-5'-O-DMT-3'-O-TBDMS-cytidine

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine

Description: It is used for special nucleoside or RNA modification.
CAT: BRP-00159
CAS: 81246-81-3
Molecular Formula: C36H44N2O8Si
Molecular Weight: 660.83
Purity: ≥95%
Appearance: White Solid
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Density: 1.3±0.1 g/cm3
InChIKey: ZATGYRPVDYINRF-WXQJYUTRSA-N
CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1O)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: 1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C36H44N2O8Si/c1-35(2,3)47(6,7)46-32-29(45-33(31(32)40)38-22-21-30(39)37-34(38)41)23-44-36(24-11-9-8-10-12-24,25-13-17-27(42-4)18-14-25)26-15-19-28(43-5)20-16-26/h8-22,29,31-33,40H,23H2,1-7H3,(H,37,39,41)/t29-,31-,32-,33-/m1/s1
Synonyms: 5'-DMT-3'-tBDSilyl Uridine; 5'-O-DMT-3'-O-TBDMS uridine; 5'-O-(4,4'-Dimethoxytrityl)-3'-O-t-butyldimethylsilyl uridine; 3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)uridine; 1-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-3-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]uridine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine

Description: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine, an imperative compound employed in the field of biomedicine, exhibits noteworthy significance in the process of synthesizing nucleic acids for genetic investigations. Through the modification of nucleotides, this compound facilitates precise administration of therapeutic drugs and gene therapy. Expanding its utility, it finds applications in addressing a myriad of ailments including cancer, viral infections, and genetic disorders, thereby serving as an indispensable instrument in the realm of biomedical research.
CAT: BRP-00160
CAS: 81256-89-5
Molecular Formula: C41H51N5O8Si
Molecular Weight: 769.96
Purity: 97%
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Density: 1.25±0.1 g/cm3(Predicted)
InChIKey: XAIQBZNFPUNWMQ-CJEGOSRCSA-N
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O[Si](C)(C)C(C)(C)C)O
IUPAC Name: N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C41H51N5O8Si/c1-25(2)36(48)44-39-43-35-32(37(49)45-39)42-24-46(35)38-33(47)34(54-55(8,9)40(3,4)5)31(53-38)23-52-41(26-13-11-10-12-14-26,27-15-19-29(50-6)20-16-27)28-17-21-30(51-7)22-18-28/h10-22,24-25,31,33-34,38,47H,23H2,1-9H3,(H2,43,44,45,48,49)/t31-,33-,34-,38-/m1/s1
Synonyms: 5'-DMT-3'-tBDSilyl Guanosine (n-ibu); 5'-DMT-3'-TBDMS-ibu-rG; N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-3'-O-tert-butyldimethylsilyl guanosine

N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine

Description: N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a cutting-edge and technologically advanced biomedical compound aiding in studying an extensive array of debilitating diseases.
CAT: BRP-00161
CAS: 123956-65-0
Molecular Formula: C38H47N3O8Si
Molecular Weight: 701.88
Purity: 98%
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Storage: Store at 2-8°C
Density: 1.19±0.1 g/cm3 (Predicted)
InChIKey: RWIUJRXXJFJUFX-HYGOWAQNSA-N
Solubility: Soluble in DMSO
CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O[Si](C)(C)C(C)(C)C)O
IUPAC Name: N-[1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C38H47N3O8Si/c1-25(42)39-32-22-23-41(36(44)40-32)35-33(43)34(49-50(7,8)37(2,3)4)31(48-35)24-47-38(26-12-10-9-11-13-26,27-14-18-29(45-5)19-15-27)28-16-20-30(46-6)21-17-28/h9-23,31,33-35,43H,24H2,1-8H3,(H,39,40,42,44)/t31-,33-,34-,35-/m1/s1
Synonyms: 5'-DMT-3'-TBDMS-Ac-rC; N-(1-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-3-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide; 3'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N4-acetyl cytidine; 3'-O-TBDMS-5'-O-DMT-N4-Ac cytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]cytidine; 5'-DMT-3'-TBDMS-C(Ac)

N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine

Description: It is used for nucleoside modification, amidite and nucleic acid synthesis.
CAT: BRP-00162
CAS: 81256-88-4
Molecular Formula: C44H49N5O7Si
Molecular Weight: 787.97
Purity: 96%
Appearance: White to Off-white Powder
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Storage: Store at 2-8°C
Density: 1.2±0.1 g/cm3
InChIKey: QNPRMZLAAWKAPQ-GNECSJIWSA-N
Solubility: Soluble in DMSO
CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1O)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
IUPAC Name: N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C44H49N5O7Si/c1-43(2,3)57(6,7)56-38-35(55-42(37(38)50)49-28-47-36-39(45-27-46-40(36)49)48-41(51)29-14-10-8-11-15-29)26-54-44(30-16-12-9-13-17-30,31-18-22-33(52-4)23-19-31)32-20-24-34(53-5)25-21-32/h8-25,27-28,35,37-38,42,50H,26H2,1-7H3,(H,45,46,48,51)/t35-,37-,38-,42-/m1/s1
Synonyms: 5'-DMT-3'-tBDSilyl Adenosine (n-bz); N6-benzoyl-5'-O-DMT-3'-O-TBDMS-adenosine; N6-benzoyl-3'-O-t-butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-adenosine; 5'-DMT-3'-TBDMS-Bz-rA; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine
* Only for research. Not suitable for any diagnostic or therapeutic use.
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