Nucleotides - RNA / BOC Sciences

Guanosine 5'-triphosphate-5'-adenosine

Description: Guanosine 5'-triphosphate-5'-adenosine, the 5′ cap analog, is a fluorescent substrate analog.

CAT: BRP-00209

CAS: 10527-47-6

MF: C20H27N10O17P3

MF: 772.41

Purity: ≥95% by HPLC

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Density: 2.61±0.1 g/cm3

InChIKey: PMJUJCUPNRCBNP-INFSMZHSSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C5N=C(NC6=O)N)O)O)O)O)N

IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate

InChI: InChI=1S/C20H27N10O17P3/c21-14-8-15(24-3-23-14)29(4-25-8)18-12(33)10(31)6(44-18)1-42-48(36,37)46-50(40,41)47-49(38,39)43-2-7-11(32)13(34)19(45-7)30-5-26-9-16(30)27-20(22)28-17(9)35/h3-7,10-13,18-19,31-34H,1-2H2,(H,36,37)(H,38,39)(H,40,41)(H2,21,23,24)(H3,22,27,28,35)/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1

Synonyms: GpppA; Guanosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with adenosine; Adenosine 5'-(tetrahydrogen triphosphate), 5'→5'-ester with guanosine; Guanosine 5'-(tetrahydrogen triphosphate), 5'→5'-ester with adenosine; Guanosine triphosphate, 5'→5'-ester with adenosine; Gp3A; Gp3A (dinucleotide); P1-Adenosine-5' P3-guanosine-5' triphosphate

Related CAS: 1613387-42-0 (trisodium salt)

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine

Description: N7-Methyl-guanosine-5’-triphosphate-5’-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription.

CAT: BRP-00210

CAS: 62828-63-1

MF: C21H29N10O17P3

MF: 786.43

Purity: ≥95% by HPLC

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InChIKey: QQOHNVHGNZYSBP-XPWFQUROSA-N

CanonicalSMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] phosphate

InChI: InChI=1S/C21H29N10O17P3/c1-29-6-31(17-10(29)18(36)28-21(23)27-17)20-14(35)12(33)8(46-20)3-44-50(39,40)48-51(41,42)47-49(37,38)43-2-7-11(32)13(34)19(45-7)30-5-26-9-15(22)24-4-25-16(9)30/h4-8,11-14,19-20,32-35H,2-3H2,1H3,(H7-,22,23,24,25,27,28,36,37,38,39,40,41,42)/t7-,8-,11-,12-,13-,14-,19-,20-/m1/s1

Synonyms: M7-GpppA; Guanosine 5'-(tetrahydrogen triphosphate), 7-methyl-, inner salt, P''→5'-ester with adenosine; 7-Methylguanosine 5'-(tetrahydrogen triphosphate) inner salt, P''→5'-ester with adenosine; Adenosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt; m7GpppA

Related CAS: 75252-10-7 (diammonium salt)

ARCA Sodium

Description: ARCA Sodium, a potent inhibitor of the Nav1.5 cardiac sodium channel, is adeptly utilized in mitigating arrhythmias, such as atrial fibrillation. Additionally, it exhibits promise as a therapeutic agent for the management of chronic pain conditions.

CAT: BRP-00211

MF: C22H31N10O18P3 (free acid)

MF: 816.46 (free acid)

Purity: ≥95% by HPLC

Appearance: Clear colorless to faint yellow Liquid

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Synonyms: ARCA, sodium salt; Anti Reverse Cap Analog sodium salt; m7(3'-O-methy)G(5')ppp(5')G sodium salt; 3'-O-Me-m7G(5')ppp(5')G sodium salt; m27, 3'-OGP3G (ARCA Cap Analog) sodium salt; 3'-O-Methyl-m7GpppG sodium salt; ARCA (anti-reverse cap analog) sodium salt; m27,3'OGpppG sodium salt; N7-Methyl-3'-O-Methyl-Guanosine-5'-Triphosphate-5'-Guanosine, sodium salt

Related CAS: 400806-46-4 (free acid) ; 400806-60-2 (trisodium salt)

M7G(3'-OMe-5')pppA(2'-OMe)

Description: M7G(3'-OMe-5')pppA(2'-OMe) is a cap analogue for mRNA synthesis in vitro.

CAT: BRP-00212

MF: C23H33N10O17P3

MF: 814.49

Purity: ≥95% by HPLC

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InChIKey: CDTPPKGWEOGAMN-LAMCKDNKSA-N

IUPAC Name: 2-amino-9-((2R,3R,4S,5R)-5-((((((((((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium

InChI: InChI=1S/C23H33N10O17P3/c1-31-8-33(19-12(31)20(36)30-23(25)29-19)21-14(35)15(43-2)10(48-21)5-46-52(39,40)50-53(41,42)49-51(37,38)45-4-9-13(34)16(44-3)22(47-9)32-7-28-11-17(24)26-6-27-18(11)32/h6-10,13-16,21-22,34-35H,4-5H2,1-3H3,(H7-,24,25,26,27,29,30,36,37,38,39,40,41,42)/t9-,10-,13-,14-,15-,16-,21-,22-/m1/s1

Synonyms: (3'-OMe-m7G)(5')ppp(5')(2'-OMe-A)

2'-Deoxyuridine 5'-triphosphate

Description: 2'-Deoxyuridine 5'-triphosphate, a nucleotide analog, is utilized in DNA synthesis and repair. The drug finds wide application in treating viral infections, most notably herpes and HIV. Administration of this drug leads to the termination of chain growth and subsequent inhibition of viral replication. It is a substrate for DNA polymerase and is incorporated during DNA chain elongation. Such incorporation plays a significant role in the fight against virally induced diseases.

CAT: BRP-00214

CAS: 1173-82-6

MF: C9H15N2O14P3

MF: 468.14

Purity: 95%

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Density: 2.010±0.06 g/cm3

InChIKey: AHCYMLUZIRLXAA-SHYZEUOFSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1C(C(OC1N2C=CC(=O)NC2=O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O

IUPAC Name: [[(2R,3S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H15N2O14P3/c12-5-3-8(11-2-1-7(13)10-9(11)14)23-6(5)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1

Synonyms: 2'-Deoxyuridine-5'-Triphosphoric Acid; Deoxyuridine triphosphate; deoxy-UTP; dUTP; Deoxyuridine-5'-Triphosphate; 2'-deoxyuridine 5'-(tetrahydrogen triphosphate); Uridine 5'-(tetrahydrogen triphosphate), 2'-deoxy-; ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate

Related CAS: 93919-43-8 (disodium salt) ; 1365987-12-7 (tetrasodium salt) ; 102814-08-4 (trisodium salt) ; 6152-08-5 (monosodium salt) ; 94736-09-1 (x-sodium salt)

m7GpppAmpG

Description: m7GpppAmpG is a trinucleotide 5' cap analog with the capping efficiencies for the obtained RNAs of 90%. It is used to transcribe 5'cap mRNA in vitro to produce the Cap 1 structure, which is more suitable for mammalian systems and has higher transcriptional efficiency than the Cap 0 structure. m7GpppAmpG Cap Analog is a co-transcriptional capping agent that transcribes 5' capped mRNA in vitro to form the Cap 1 structure.

CAT: BRP-00215

CAS: 62858-30-4

MF: C32H43N15O24P4

MF: 1145.67

Purity: ≥95% by HPLC

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InChIKey: AGWRKMKSPDCRHI-UQTMIEBXSA-N

CanonicalSMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)OC)OP(=O)(O)OCC7C(C(C(O7)N8C=NC9=C8N=C(NC9=O)N)O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[(2R,3R,4R,5R)-3-[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] phosphate

InChI: InChI=1S/C32H43N15O24P4/c1-44-9-47(25-15(44)27(53)43-32(35)41-25)29-19(51)17(49)11(67-29)4-64-73(56,57)70-75(60,61)71-74(58,59)65-5-12-20(21(62-2)30(68-12)45-7-38-13-22(33)36-6-37-23(13)45)69-72(54,55)63-3-10-16(48)18(50)28(66-10)46-8-39-14-24(46)40-31(34)42-26(14)52/h6-12,16-21,28-30,48-51H,3-5H2,1-2H3,(H11-,33,34,35,36,37,40,41,42,43,52,53,54,55,56,57,58,59,60,61)/t10-,11-,12-,16-,17-,18-,19-,20-,21-,28-,29-,30-/m1/s1

Synonyms: m7G(5')ppp(5')(2'-OMeA)pG; GAG; Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt; Adenosine 5'-(tetrahydrogen triphosphate), guanylyl-(5'→3')-2'-O-methyl-, P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium inner salt; m7GpppA2'OmepG

Related CAS: 2941382-07-4 (trisodium salt) ; 2710263-09-3 (triammonium salt)

3'Ome-m7GpppAmpG

Description: 3'Ome-m7GpppAmpG is a trinucleotide Cap analogue containing a locked nucleic acid ( LNA ) molecule. 3'Ome-m7GpppAmpG shows a significant translational efficiency. 3'Ome-m7GpppAmpG can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization.

CAT: BRP-00216

CAS: 2089461-55-0

MF: C33H45N15O24P4

MF: 1159.69

Purity: ≥95% by HPLC

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InChIKey: QLKZOMAEOBMBOC-RKTALREWSA-N

CanonicalSMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)OC)OP(=O)(O)OCC7C(C(C(O7)N8C=NC9=C8N=C(NC9=O)N)O)O)OC)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-4-hydroxy-3-methoxyoxolan-2-yl]methyl [[[(2R,3R,4R,5R)-3-[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] phosphate

InChI: InChI=1S/C33H45N15O24P4/c1-45-10-48(26-16(45)28(53)44-33(36)42-26)30-19(51)20(62-2)12(68-30)5-65-74(56,57)71-76(60,61)72-75(58,59)66-6-13-21(22(63-3)31(69-13)46-8-39-14-23(34)37-7-38-24(14)46)70-73(54,55)64-4-11-17(49)18(50)29(67-11)47-9-40-15-25(47)41-32(35)43-27(15)52/h7-13,17-22,29-31,49-51H,4-6H2,1-3H3,(H11-,34,35,36,37,38,41,42,43,44,52,53,54,55,56,57,58,59,60,61)/t11-,12-,13-,17-,18-,19-,20-,21-,22-,29-,30-,31-/m1/s1

Synonyms: 3'-OMe-GAG; (3'-OMe-m7G)(5')ppp(5')(2'-OMeA)pG; m7(3'OMeG)(5')ppp(5')(2'OMeA)pG; Guanosine, 7-methyl-3'-O-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt; m7(3'OMeG)(5')ppp(5')(2'OMeA)pG; CAP GAG (3'OMe)

Related CAS: 2863631-10-9 (trisodium salt)

m7G(5')ppp(5')(2'OMeA)pU

Description: A 5'cap analog used for co-transcriptional capping of mRNA. The product is specifically designed for self-replicating RNAs based on the genomes of positive sense strand RNA viruses such as Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV), and Sindbis virus (SIN).

CAT: BRP-00217

CAS: 2734858-38-7

MF: C31H42N12O25P4

MF: 1106.63

Purity: ≥95% by HPLC

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InChIKey: FTIHNRSFQMJZNB-MPTQKLLZSA-N

Solubility: Store at -20°C

CanonicalSMILES: O=C1N=C(N)NC2=C1[N+](=CN2C3OC(COP(=O)([O-])OP(=O)(O)OP(=O)(O)OCC4OC(N5C=NC=6C(=NC=NC65)N)C(OC)C4OP(=O)(O)OCC7OC(N8C=CC(=O)NC8=O)C(O)C7O)C(O)C3O)C

IUPAC Name: 2-amino-9-((2R,3R,4S,5R)-5-((((((((((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-(((((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)-4-methoxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium

InChI: InChI=1S/C31H42N12O25P4/c1-40-10-43(25-16(40)26(49)39-30(33)38-25)28-20(48)18(46)12(64-28)6-61-70(53,54)67-72(57,58)68-71(55,56)62-7-13-21(22(59-2)29(65-13)42-9-36-15-23(32)34-8-35-24(15)42)66-69(51,52)60-5-11-17(45)19(47)27(63-11)41-4-3-14(44)37-31(41)50/h3-4,8-13,17-22,27-29,45-48H,5-7H2,1-2H3,(H9-,32,33,34,35,37,38,39,44,49,50,51,52,53,54,55,56,57,58)/t11-,12-,13-,17-,18-,19-,20-,21-,22-,27-,28-,29-/m1/s1

Synonyms: Uridine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt; (m7)Gppp(5')(m2'O)ApU; m7G(5')ppp(5')(2'-OMeA)pU; m7Gppp(5')A2'OMepU; m7GpppAmpU trinucleotide cap; GAU

Related CAS: 2941382-10-9 (trisodium salt)

Cytidine 5'-triphosphate

Description: Cytidine 5'-triphosphate is a vital molecule in biomedicine that serves as a building block for DNA and RNA synthesis. It plays a crucial role in cellular processes, such as cell growth, proliferation, and signal transduction. Cytidine 5'-triphosphate is used in the treatment of certain viral infections and cancer where it acts as an antiviral and antineoplastic agent.

CAT: BRP-00309

CAS: 65-47-4

MF: C9H16N3O14P3

MF: 483.16

Purity: ≥98% by AX-HPLC

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Storage: Store at -20 °C

Density: 2.5±0.1 g/cm3

Melting Point: 215-218 °C

Boiling Point: 849.2±75.0 °C at 760 mmHg

InChIKey: PCDQPRRSZKQHHS-XVFCMESISA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H16N3O14P3/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

Synonyms: CTP; Cytidine triphosphate; Cytidine 5'-(tetrahydrogen triphosphate)

Guanosine 5'-triphosphate

Description: Guanosine triphosphate (GTP) is a guanine nucleotide containing three phosphate groups esterified to the sugar moiety. GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

CAT: BRP-00310

CAS: 86-01-1

MF: C10H16N5O14P3

MF: 523.18

Purity: ≥98% by AX-HPLC

Appearance: Solid

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Storage: Store at -20 °C

Density: 2.8±0.1 g/cm3

Boiling Point: 1028.3 °C at 760 mmHg

InChIKey: XKMLYUALXHKNFT-UUOKFMHZSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N

IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1

Synonyms: D-Guanosine 5'-triphosphate; Guanosine triphosphate; Guanosine 5'-triphosphoric acid; pppG; guanosine 5'-O-(triphosphate); [[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

Related CAS: 36051-31-7 (trisodium salt) ; 56001-37-7 (disodium salt)

Uridine 5’-triphosphate

Description: Uridine 5’-triphosphate, a vital RNA building block produced endogenously in human cells, plays a significant role in cell metabolism. Its indispensable value in the biomedical industry for DNA sequencing, gene expression analysis, and likely therapeutic applications cannot be overemphasized. The extensive possibilities of applying this nucleotide in the treatment of cardiovascular diseases, neurological disorders, and select types of cancer is worth being explored.

CAT: BRP-00311

CAS: 63-39-8

MF: C9H15N2O15P3

MF: 484.14

Purity: ≥95% by HPLC

Appearance: Colorless Liquid

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Storage: Store at 2-8°C

Density: 2.106±0.06 g/cm3 (Predicted)

Boiling Point: 868.1±75.0 °C at 760 mmHg

InChIKey: PGAVKCOVUIYSFO-XVFCMESISA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

Synonyms: UTP; Uridine 5'-(tetrahydrogen triphosphate); uridine triphosphate; Uteplex

Related CAS: 74674-72-9 (x-sodium salt) ; 36051-69-1 (disodium salt) ; 19817-92-6 (trisodium salt) ; 1476-50-2 (monosodium salt) ; 14264-46-1 (tetrasodium salt)

Uridine 5'-triphosphate sodium salt

Description: The solution form of UTP. UTP is a pyrimidine nucleoside triphosphate playing an important role as a substrate for the synthesis of RNA during transcription. It also acts as a dual agonist of purinergic P2Y2 and P2Y4 receptors.

CAT: BRP-00317

CAS: 74674-72-9

MF: C9H15N2O15P3 (free acid)

MF: 484.14 (free acid)

Purity: ≥95% by HPLC

Appearance: Clear Aqueous Solution

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Storage: Store at -20 °C

Synonyms: UTP sodium salt; Uridine 5'-triphosphate, sodium salt; Uridine 5'-(tetrahydrogen triphosphate) sodium salt; Uridine 5'-trisphosphate sodium salt (1:x); Uridine 5'-(tetrahydrogen triphosphate), sodium salt (1:x)

Related CAS: 63-39-8 (free acid) ; 36051-69-1 (disodium salt) ; 19817-92-6 (trisodium salt) ; 1476-50-2 (monosodium salt) ; 14264-46-1 (tetrasodium salt)

Uridine 5'-triphosphate trisodium salt monohydrate

Description: UTP serves as a building block for RNA synthesis and modification, playing a vital role in cellular processes such as gene expression and protein synthesis. It is often utilized in research involving RNA labeling, transcription and RNA structural studies.

CAT: BRP-00318

CAS: 1266569-92-9

MF: C9H14N2Na3O16P3

MF: 568.10

Purity: ≥90% by HPLC

Appearance: lyophilized

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InChIKey: KRFVCRUFVQMDGT-ODQFIEKDSA-K

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.O.[Na+].[Na+].[Na+]

IUPAC Name: trisodium;[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;hydrate

InChI: InChI=1S/C9H15N2O15P3.3Na.H2O/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;;1H2/q;3*+1;/p-3/t4-,6-,7-,8-;;;;/m1..../s1

Synonyms: Uridine 5'-(tetrahydrogen triphosphate), sodium salt, hydrate (1:3:1); Uridine 5'-triphosphate trisodium salt hydrate; UTP sodium salt hydrate; Uridine 5'-triphosphate, sodium salt hydrate

Related CAS: 19817-92-6 (anhydrous) ; 63-39-8 (anhydrous free acid) ; 116295-90-0 (dihydrate)

m7GpppGmpG

Description: m7GpppGmpG is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86%.

CAT: BRP-00327

CAS: 1258049-00-1

MF: C32H43N15O25P4

MF: 1161.66

Purity: ≥98%

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InChIKey: CDWLIVSWBYRIEX-ZQWUJQRXSA-N

CanonicalSMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C5N=C(NC6=O)N)OC)OP(=O)(O)OCC7C(C(C(O7)N8C=NC9=C8N=C(NC9=O)N)O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] phosphate

InChI: InChI=1S/C32H43N15O25P4/c1-44-8-47(23-14(44)26(54)43-32(35)40-23)28-18(51)16(49)10(68-28)4-65-74(57,58)71-76(61,62)72-75(59,60)66-5-11-19(20(63-2)29(69-11)46-7-37-13-22(46)39-31(34)42-25(13)53)70-73(55,56)64-3-9-15(48)17(50)27(67-9)45-6-36-12-21(45)38-30(33)41-24(12)52/h6-11,15-20,27-29,48-51H,3-5H2,1-2H3,(H12-,33,34,35,38,39,40,41,42,43,52,53,54,55,56,57,58,59,60,61,62)/t9-,10-,11-,15-,16-,17-,18-,19-,20-,27-,28-,29-/m1/s1

Synonyms: EZ Cap Reagent GG; EZ Cap Reagent GG for co-transcriptional capping of mRNA; m7G(5')ppp(5')(2'OMeG)pG; Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methylguanylyl-(3'→5')-, inner salt; m7Gppp(2'OMeG)pG; CAP GGG m7G(5')ppp(5')(2'OMeG)pG; GGG

Related CAS: 2638447-82-0 (tetraammonium salt) ; 2924872-05-7 (trisodium salt)

m7GpppGmpG ammonium salt

Description: m7GpppGmpG ammonium is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86%.

CAT: BRP-00328

MF: C32H43N15O25P4 (free acid)

MF: 1161.67 (free acid)

Purity: ≥98%

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Synonyms: CAP GGG m7G(5')ppp(5')(2'OMeG)pG 100mM Ammonium; CAP GGG m7G(5')ppp(5')(2'OMeG)pG Ammonium salt; GGG Ammonium salt; m7G(5')ppp(5')(2'OMeG)pG Ammonium salt; m7Gppp(2'OMeG)pG Ammonium salt

Related CAS: 1258049-00-1 (free acid) ; 2638447-82-0 (tetraammonium salt) ; 2924872-05-7 (trisodium salt)

m7(3'OMeG)(5')ppp(5')(2'OMeG)pG

Description: EZ Cap Reagent GG (3'OMe) is a co-transcription capping reagent.

CAT: BRP-00329

CAS: 2089461-54-9

MF: C33H45N15O25P4

MF: 1175.69

Purity: ≥95% by AX-HPLC

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InChIKey: UIMYJBJWBAHYJD-UQTMIEBXSA-N

CanonicalSMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C5N=C(NC6=O)N)OC)OP(=O)(O)OCC7C(C(C(O7)N8C=NC9=C8N=C(NC9=O)N)O)O)OC)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-4-hydroxy-3-methoxyoxolan-2-yl]methyl [[[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] phosphate

InChI: InChI=1S/C33H45N15O25P4/c1-45-9-48(24-15(45)27(54)44-33(36)41-24)29-18(51)19(63-2)11(69-29)5-66-75(57,58)72-77(61,62)73-76(59,60)67-6-12-20(21(64-3)30(70-12)47-8-38-14-23(47)40-32(35)43-26(14)53)71-74(55,56)65-4-10-16(49)17(50)28(68-10)46-7-37-13-22(46)39-31(34)42-25(13)52/h7-12,16-21,28-30,49-51H,4-6H2,1-3H3,(H12-,34,35,36,39,40,41,42,43,44,52,53,54,55,56,57,58,59,60,61,62)/t10-,11-,12-,16-,17-,18-,19-,20-,21-,28-,29-,30-/m1/s1

Synonyms: EZ Cap Reagent GG (3' OMe) for co-transcriptional capping of mRNA; EZ Cap Reagent GG (3' OMe); GGG(3'OMe); m7(3'OMeG)ppp(2'OMeG)pG

Related CAS: 2924872-08-0 (trisodium salt)

m7Gpppm6AmpG

Description: m7Gpppm6AmpG is a trinucleotide mRNA 5’ cap analogs. m7Gpppm6AmpG can be used for RNA synthesis in vitro.

CAT: BRP-00330

CAS: 71340-22-2

MF: C33H45N15O24P4

MF: 1159.69

Purity: ≥98%

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InChIKey: DIMGFCCAJKOSNT-RKTALREWSA-N

CanonicalSMILES: CNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)([O-])OCC4C(C(C(O4)[N+]5=CN(C6=C5N=C(NC6=O)N)C)O)O)OP(=O)(O)OCC7C(C(C(O7)N8C=NC9=C8N=C(NC9=O)N)O)O)OC

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[[(2R,3R,4R,5R)-3-[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-4-methoxy-5-[6-(methylamino)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] phosphate

InChI: InChI=1S/C33H45N15O24P4/c1-36-23-14-24(38-7-37-23)46(8-39-14)31-22(63-3)21(70-73(55,56)64-4-11-17(49)19(51)29(67-11)47-9-40-15-25(47)41-32(34)43-27(15)53)13(69-31)6-66-75(59,60)72-76(61,62)71-74(57,58)65-5-12-18(50)20(52)30(68-12)48-10-45(2)16-26(48)42-33(35)44-28(16)54/h7-13,17-22,29-31,49-52H,4-6H2,1-3H3,(H10-,34,35,36,37,38,41,42,43,44,53,54,55,56,57,58,59,60,61,62)/t11-,12-,13-,17-,18-,19-,20-,21-,22-,29-,30-,31-/m1/s1

Synonyms: Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-N-methyl-2'-O-methylguanylyl-(3'→5')-, inner salt; Adenosine 5'-(tetrahydrogen triphosphate), guanylyl-(5'→3')-N-methyl-2'-O-methyl-, P''→5'-ester with 2-amino-6,9-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-1H-purinium, inner salt; CAP GAG(m6A) m7G(5')ppp(5')(2'OMe,m6A)pG; GAG(m6A); m7Gppp(2'OMe,m6A)pG; m7G(5')ppp(5')(2'OMe,m6A)pG

Related CAS: 2956650-99-8 (trisodium salt)

m7Gpppm6AmpG ammonium salt

Description: m7Gpppm6AmpG ammonium salt is a trinucleotide mRNA 5' cap analogs. m7Gpppm6AmpG ammonium can be used for RNA synthesis in vitro.

CAT: BRP-00331

MF: C33H45N15O24P4 (free acid)

MF: 1159.69 (free acid)

Purity: ≥98%

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Synonyms: CAP GAG(m6A) m7G(5')ppp(5')(2'OMe,m6A)pG Ammonium; GAG(m6A) ammonium salt; m7Gppp(2'OMe,m6A)pG ammonium salt; m7G(5')ppp(5')(2'OMe,m6A)pG ammonium salt

Related CAS: 71340-22-2 (free acid)

8-Azidoadenosine-5'-Triphosphate

Description: 8-Azidoadenosine-5'-Triphosphate is a crucial tool in compound for studying ATP-dependent processes. With its azido group, it enables selective photo-crosslinking to ATP-binding proteins and subsequent identification. Widely used in drug discovery and proteomics, it aids in investigating ATP-dependent diseases like cancer and neurodegenerative disorders.

CAT: BRP-00332

CAS: 53696-59-6

MF: C10H15N8O13P3

MF: 548.19

Purity: ≥90% by AX-HPLC

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Storage: Store at -20°C

Application: Affinity Labels

InChIKey: PQISXOFEOCLOCT-UUOKFMHZSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C(=N2)N=[N+]=[N-])C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

IUPAC Name: [[(2R,3S,4R,5R)-5-(6-amino-8-azidopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H15N8O13P3/c11-7-4-8(14-2-13-7)18(10(15-4)16-17-12)9-6(20)5(19)3(29-9)1-28-33(24,25)31-34(26,27)30-32(21,22)23/h2-3,5-6,9,19-20H,1H2,(H,24,25)(H,26,27)(H2,11,13,14)(H2,21,22,23)/t3-,5-,6-,9-/m1/s1

Synonyms: 8-Azido-ATP; 8-Azidoadenosine 5'-(tetrahydrogen triphosphate); 8-Azido ATP; 8-Azidoadenosine 5'-triphosphate; 8-Azidoadenosine triphosphate

Related CAS: 871119-02-7 (disodium salt) ; 1418217-88-5 (monosodium salt) ; 60731-49-9 (triethylamine salt (1:3)) ; 66895-06-5 (triethylamine salt (1:1)) ; 72504-51-9 (triethylamine salt (1:x))

Ara-CTP

Description: ara-Cytidine-5'-triphosphate (ara-CTP) is an inhibitor of DNA synthesis, DNA ligases and polymerases that is used for the treatment of acute myeloid leukemia.

CAT: BRP-00333

CAS: 13191-15-6

MF: C9H16N3O14P3

MF: 483.16

Purity: ≥90% by AX-HPLC

Appearance: clear aqueous solution

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Storage: Store at -20°C

Density: 2.5±0.1 g/cm3

Boiling Point: 849.2±75.0 °C at 760 mmHg

Application: Nucleic Acid Synthesis Inhibitors

InChIKey: PCDQPRRSZKQHHS-CCXZUQQUSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

Synonyms: 1-β-D-arabinofuranosylcytosine TP; Aracytidine-5'-Triphosphate; ara-Cytidine-5'-triphosphate; Arabinofuranosylcytosine triphosphate; 4-Amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]-2(1H)-pyrimidinone; 1-β-D-Arabinofuranosylcytosine 5'-triphosphate; 1-β-D-Arabinosylcytosine triphosphate; 1-β-Arabinofuranosylcytosine 5'-triphosphate; Ara-C triphosphate; Arabinosylcytosine 5'-triphosphate; AraCTP; Cytosine arabinoside 5'-triphosphate; Cytosine β-D-arabinofuranoside-5'-triphosphate

Related CAS: 102601-42-3 (disodium salt) ; 1179342-85-8 (triammonium salt) ; 1179343-17-9 (trisodium salt)