What are nucleotides used for in molecular biology?

Nucleotides serve as substrates for enzymatic reactions such as DNA synthesis, RNA transcription, and IVT mRNA production.

What is the difference between dNTPs and NTPs?

dNTPs are used for DNA synthesis, while NTPs are used for RNA synthesis and transcription reactions.

Why is nucleotide purity important?

Impurities can inhibit enzyme activity and negatively affect reaction efficiency and fidelity.

Are nucleotides suitable for IVT mRNA synthesis?

Yes, high-purity NTPs are essential substrates for RNA polymerase-driven IVT mRNA workflows.

How does lot consistency affect nucleotide performance?

Consistent lot quality ensures reproducible enzymatic performance across repeated experiments and scale-up processes.

Nucleotides - RNA / BOC Sciences

N1-MethylpseudoUridine-5'-Triphosphate

Description: N1-MethylpseudoUridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The sodium form N1-MethylpseudoUridine-5'-Triphosphate Sodium (B2706-358101) is in stock.

CAT: BRP-00008

CAS: 1428903-59-6

Molecular Formula: C10H17N2O15P3

Molecular Weight: 498.17

Purity: ≥95%

Appearance: Clear colourless solution

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Storage: Storage at -20°C

Density: 2.010±0.06 g/cm3 (Predicted)

InChIKey: OLRONOIBERDKRE-XUTVFYLZSA-N

CanonicalSMILES: CN1C=C(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5S)-3,4-dihydroxy-5-(1-methyl-2,4-dioxopyrimidin-5-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H17N2O15P3/c1-12-2-4(9(15)11-10(12)16)8-7(14)6(13)5(25-8)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5-8,13-14H,3H2,1H3,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t5-,6-,7-,8+/m1/s1

Synonyms: m1Ψ; 1-Methylpseudouridine-5'-Triphosphate; N1-Methylpseudo-UTP; 1-Methylpseudo-UTP; N1-Methyl Pseudo UTP; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1-methyl-2,4(1H,3H)-pyrimidinedione; 1-N-Methyl-pseudo-UTP

Related CAS: 1931922-77-8 (tetrasodium salt) ; 3056945-59-3 (trisodium salt)

5-Methoxyuridine 5'-triphosphate

Description: 5-Methoxyuridine 5'-triphosphate is a vital component used in the biomedical industry for various applications serving as a key building block in the research and development of RNA molecules for research purposes. Additionally, it plays a significant role in studying RNA post-transcriptional modifications and RNA labeling techniques. Its incorporation supports investigations related to drug discovery, gene expression profiling and disease understanding.

CAT: BRP-00009

CAS: 847649-65-4

Molecular Formula: C10H17N2O16P3

Molecular Weight: 514.17

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Density: 2.03±0.1 g/cm3

InChIKey: ULUMTYRKOVZPNM-JXOAFFINSA-N

CanonicalSMILES: COC1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methoxy-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H17N2O16P3/c1-24-4-2-12(10(16)11-8(4)15)9-7(14)6(13)5(26-9)3-25-30(20,21)28-31(22,23)27-29(17,18)19/h2,5-7,9,13-14H,3H2,1H3,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t5-,6-,7-,9-/m1/s1

Synonyms: m5U; 5-Methoxy UTP; 5-Methoxy-UTP; 5-OMe-UTP; 5-Methoxyuridine 5'-(tetrahydrogen triphosphate); 5OMeUTP

Adenosine 5'-monophosphate

Description: Adenosine monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.

CAT: BRP-00022

CAS: 61-19-8

Molecular Formula: C10H14N5O7P

Molecular Weight: 347.22

Purity: ≥95%

Appearance: White solid

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Storage: Store at -20 °C, under inert atmosphere

Density: 2.32±0.1 g/cm³ (Predicted)

Melting Point: 178-185 °C

Boiling Point: 798.5±70.0 °C (Predicted)

InChIKey: UDMBCSSLTHHNCD-KQYNXXCUSA-N

Solubility: Slightly soluble in Water (Sonicated)

CanonicalSMILES: C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

Synonyms: 5'-adenylic acid; adenosine phosphate; Adenosine monophosphate; adenylic acid; adenosine 5'-phosphate; 5'-AMP; Cardiomone; Lycedan; Phosaden; AMP; Vitamin B8; My-B-Den

Related CAS: 18422-05-4 (monohydrate) ; 13474-03-8 (sodium salt)

Adenosine 5'-monophosphate disodium salt

Description: Adenosine 5'-monophosphate disodium salt is a pivotal compound in the biomedical industry, exhibiting as an elemental constituent concerning cellular energy metabolism while simultaneously serving as a precursor facilitating adenosine triphosphate (ATP) research.

CAT: BRP-00023

CAS: 4578-31-8

Molecular Formula: C10H12N5Na2O7P

Molecular Weight: 391.19

Purity: 98%

Appearance: White Powder

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Storage: Store at -20°C

Melting Point: 232-235 °C

InChIKey: QGXLVXZRPRRCRP-IDIVVRGQSA-L

Solubility: Soluble in Water, Dimethyl Sulfoxide, Methanol

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])[O-])O)O)N.[Na+].[Na+]

IUPAC Name: disodium;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate

InChI: InChI=1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

Synonyms: 5'-Adenylic acid, sodium salt (1:2); 5'-Adenylic acid, disodium salt; 5'-AMP disodium salt; Adenosine 5'-phosphate disodium salt; Adenylic acid disodium salt; AMP disodium salt; Disodium 5'-AMP; Disodium 9-(β-D-ribofuranosyl)adenine 5'-monophosphate; Disodium adenosine 5'-phosphate; Disodium adenylate; Disodium AMP; Adenosine Phosphate Disodium; 5'-AMP disodium salt; Disodium adenosine 5'-phosphate

Related CAS: 61-19-8 (free acid) ; 132-00-3 (monosodium salt) ; 13474-03-8 (x-sodium salt) ; 1193174-04-7 (tetrasodium salt)

Adenosine 5'-diphosphate

Description: Adenosine 5'-diphosphate (ADP) is a central component of energy storage, metabolism, and signal transduction in vivo.

CAT: BRP-00024

CAS: 58-64-0

Molecular Formula: C10H15N5O10P2

Molecular Weight: 427.20

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20 °C, under inert atmosphere

Density: 2.49±0.1 g/cm3 (Predicted)

Melting Point: >145 °C (dec.)

Boiling Point: 877.7±75.0 °C at 760 mmHg

InChIKey: XTWYTFMLZFPYCI-KQYNXXCUSA-N

Solubility: Soluble in DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N

IUPAC Name: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate

InChI: InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

Synonyms: Adenosine diphosphate; ADP; adenosine pyrophosphate; 5'-Adenylphosphoric acid; adenosine 5'-pyrophosphate; Adenosindiphosphorsaeure; Adenosine 5'-pyrophosphoric acid; Adenosine diphosphoric acid; 5'-ADP

Related CAS: 1172-42-5 (monosodium salt) ; 16178-48-6 (disodium salt) ; 2092-65-1 (trisodium salt)

Adenosine 5'-diphosphate sodium salt

Description: Adenosine 5'-diphosphate sodium salt is a essential molecule in the biomedical industry used to study platelet aggregation, blood clotting, and purinergic signaling.

CAT: BRP-00025

CAS: 20398-34-9

Molecular Formula: C10H15N5O10P2.xNa

Molecular Weight: 427.20 (free acid)

Purity: 98%

Appearance: white to Off-white Powder

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Storage: Store at -20°C (under dark)

Synonyms: ADP Sodium; Sodium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl diphosphate; Adenosine 5'-(trihydrogen diphosphate), sodium salt (1:x); Adenosine 5'-(trihydrogen pyrophosphate), sodium salt; ADP sodium salt; Sodium adenosine 5'-diphosphate; Sodium adenosine diphosphate

Related CAS: 58-64-0 (free acid) ; 16178-48-6 (disodium salt) ; 2092-65-1 (trisodium salt) ; 1172-42-5 (monosodium salt)

Adenosine 5'-diphosphate monosodium salt

Description: Adenosine 5'-diphosphate monosodium salt, renowned for its indispensability in the biomedical sector, encompasses an array of notable applications. Its pivotal function lies in fueling cellular energy metabolism, thus serving as a foundational building block for ATP synthesis – an unyielding wellspring of energy. Furthermore, its prowess as a platelet aggregation modulator affords it immense value in cardiovascular health and thrombosis-related drug development endeavours.

CAT: BRP-00026

CAS: 1172-42-5

Molecular Formula: C10H14N5NaO10P2

Molecular Weight: 449.18

Purity: 98%

Appearance: White to Off-white Solid

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Storage: Store at -20 °C, under inert atmosphere

Density: 2.49 g/cm3

Melting Point: >174 °C (dec.)

Boiling Point: 877.7 °C at 760 mmHg

InChIKey: NYEHFIIOXORNJT-MCDZGGTQSA-M

Solubility: Soluble in Aquoues Base (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)[O-])O)O)N.[Na+]

IUPAC Name: sodium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H15N5O10P2.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1

Synonyms: Sodium ADP; Sodium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogendiphosphate; ADP, monosodium salt; Adenosine 5'-(trihydrogen diphosphate), sodium salt; Adenosine 5'-diphosphoric acid beta-sodium salt; ADP-Na

Related CAS: 58-64-0 (free acid) ; 16178-48-6 (disodium salt) ; 2092-65-1 (trisodium salt)

Adenosine 5'-diphosphate Disodium Salt

Description: Adenosine 5'-diphosphate Disodium Salt, a paramount biochemical compound widely employed in the biomedical sector, assumes a pivotal function in energy metabolism, serving as a precursor for ATP synthesis. Its applications encompass extensive research endeavors investigating cellular energetics and pathologies linked to energy insufficiency, notably metabolic disorders and mitochondrial dysfunction.

CAT: BRP-00027

CAS: 16178-48-6

Molecular Formula: C10H13N5Na2O10P2

Molecular Weight: 471.16

Purity: ≥95%

Appearance: White Powder

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Storage: Store at -20 °C

Density: 2.49 g/cm3

Boiling Point: 877.7 °C at 760 mmHg

InChIKey: ORKSTPSQHZNDSC-IDIVVRGQSA-L

Solubility: Soluble in Water

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)[O-])O)O)N.[Na+].[Na+]

IUPAC Name: disodium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H15N5O10P2.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

Synonyms: Adenosine 5'-(trihydrogen diphosphate) Disodium Salt; ADP Disodium; ADP Disodium Salt; Disodium 5'-ADP; Disodium ADP; Disodium Adenosine 5'-Diphosphate; 5'-ADP-Na2; ADP-Na2; Adenosine diphosphate disodium salt

Related CAS: 58-64-0 (free acid) ; 1172-42-5 (monosodium salt) ; 2092-65-1 (trisodium salt)

Adenosine 5'-Diphosphate Potassium Salt Dihydrate

Description: Adenosine 5'-Diphosphate Potassium Salt is a nucleotide that is widely distributed in nature.

CAT: BRP-00028

CAS: 72696-48-1

Molecular Formula: C10H14KN5O10P2.2H2O

Molecular Weight: 501.32

Purity: 97%

Appearance: White Crystal Powder

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Storage: Store at -20°C

InChIKey: HFCXEPLDPMALMF-MSQVLRTGSA-M

Solubility: Soluble in water (10 mg/mL)

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)[O-])O)O)N.O.O.[K+]

IUPAC Name: potassium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate;dihydrate

InChI: InChI=1S/C10H15N5O10P2.K.2H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);;2*1H2/q;+1;;/p-1/t4-,6-,7-,10-;;;/m1.../s1

Synonyms: Adenosine 5'-(Trihydrogen diphosphate) Potassium Salt Dihydrate

Related CAS: 70285-70-0 (anhydrous) ; 58-64-0 (anhydrous free acid)

Adenosine 5'-diphosphate monopotassium salt

Description: Adenosine 5'-diphosphate (ADP) is an adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5' position. It is produced by dephosphorylation of adenosine 5'-triphosphate by ATPases and can be converted back to ATP by ATP synthases.

CAT: BRP-00029

CAS: 70285-70-0

Molecular Formula: C10H14KN5O10P2

Molecular Weight: 465.29

Purity: ≥95%

Appearance: Crystalline Solid

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Storage: Store at -20 °C

InChIKey: ZNCWUOPIJTUALR-MCDZGGTQSA-M

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)[O-])O)N.[K+]

IUPAC Name: potassium;(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy(phosphonooxy)phosphoryl]oxymethyl]oxolan-3-olate

InChI: InChI=1S/C10H15N5O10P2.K/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1

Synonyms: Adenosine 5'-(trihydrogen diphosphate), monopotassium salt; Adenosine 5'-Diphosphate Potassium Salt; 5'-ADP monopotassium salt; ADP monopotassium salt

Related CAS: 72696-48-1 (dihydrate) ; 58-64-0 (free acid) ; 114702-55-5 (dipotassium salt)

Adenosine 5'-diphosphate trilithium salt

Description: Adenosine 5'-diphosphate trilithium salt, a paramount compound in the biomedical sector, assumes a pivotal function in diverse biochemical reactions within the organism. Renowned in research, this product facilitates the exploration of intricate intracellular signaling pathways and scrutiny of cellular metabolism.

CAT: BRP-00030

CAS: 31008-64-7

Molecular Formula: C10H12Li3N5O10P2

Molecular Weight: 445.00

Purity: 97%

Appearance: White Powder

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Storage: Store at -20 °C

InChIKey: LZGPPAHUZSOGHJ-MSQVLRTGSA-K

Solubility: Soluble in Water

CanonicalSMILES: [Li+].[Li+].[Li+].C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])[O-])O)O)N

IUPAC Name: trilithium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate

InChI: InChI=1S/C10H15N5O10P2.3Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1

Synonyms: Adenosine 5'-(trihydrogen diphosphate), trilithium salt; ADP-3Li; 5'-ADP trilithium salt; ADP trilithium salt; adenosine pyrophosphate trilithium salt; 5'-Adenylphosphoric acid trilithium salt

Related CAS: 58-64-0 (free acid)

Cytidine 5'-Monophosphate

Description: 5'-Cytidylic acid is a nucleotide that is used as a monomer in RNA.

CAT: BRP-00031

CAS: 63-37-6

Molecular Formula: C9H14N3O8P

Molecular Weight: 323.20

Purity: ≥95%

Appearance: White to off-white solid

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Storage: Store at 2-8 °C

Density: 2.15±0.1 g/cm3

Melting Point: 225 °C

Boiling Point: 678.1±65.0 °C at 760 mmHg

InChIKey: IERHLVCPSMICTF-XVFCMESISA-N

Solubility: Soluble in Water (Slightly, Heated)

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

Synonyms: Cytidylic acid; Cytidine monophosphate; 5'-CMP; cytidylate; Cytidine 5'-phosphate; CMP; Polyribocytidylic acid; Cytidine 5'-phosphoric acid

Related CAS: 13718-47-3 (monosodium salt) ; 6757-06-8 (disodium salt)

Cytidine 5'-diphosphate Trisodium Salt

Description: Cytidine 5'-diphosphate Trisodium Salt, an indispensable pharmaceutical compound in biomedicine, exhibits paramount importance in the realm of biochemical research, focusing primarily on unraveling intricate facets of cellular metabolism and enzymatic reactions. It serves as an indispensable cog in nucleic acid synthesis, acting as a precursor in the intricate orchestration of RNA molecule construction.

CAT: BRP-00034

CAS: 34393-59-4

Molecular Formula: C9H12N3Na3O11P2

Molecular Weight: 469.12

Purity: ≥95%

Appearance: White crystalline powder

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Storage: Store at -20 °C

InChIKey: JENUKVZGXGULDX-LLWADOMFSA-K

Solubility: Freely soluble in Water; Insoluble in Ethanol, Chloroform, Ether

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])[O-])O)O.[Na+].[Na+].[Na+]

IUPAC Name: trisodium;[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate

InChI: InChI=1S/C9H15N3O11P2.3Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1

Synonyms: CDP-Na3; Trisodium cytidine 5'-diphosphate; CDP Trisodium salt; Trisodium cytidine diphosphate; 5'-CDP 3Na; Cytidine 5'-(trihydrogen diphosphate), tridisodium salt

Related CAS: 63-38-7 (free acid)

Cytidine 5'-triphosphate disodium salt

Description: Cytidine 5'-triphosphate is a pyrimidine nucleoside triphosphate that is used in the synthesis of RNA by RNA polymerases. It can participate in a variety of biochemical reactions.

CAT: BRP-00035

CAS: 36051-68-0

Molecular Formula: C9H14N3Na2O14P3

Molecular Weight: 527.12

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20 °C, under inert atmosphere

Density: 2.50 g/cm3

Boiling Point: 849.2 °C at 760 mmHg

InChIKey: NFQMDTRPCFJJND-WFIJOQBCSA-L

Solubility: Soluble in Water (Slightly)

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+]

IUPAC Name: disodium;[[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate

InChI: InChI=1S/C9H16N3O14P3.2Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1

Synonyms: CTP-Na2; Cytidine Triphosphate Disodium Salt; NSC 20261; Cytidine 5'-(Tetrahydrogen triphosphate) Disodium Salt; CTP disodium Salt

Related CAS: 65-47-4 (free acid)

Guanosine 5'-triphosphoric acid disodium salt

Description: GTP could be used as a phosphoryl donor in signal transduction and protein synthesis.

CAT: BRP-00037

CAS: 56001-37-7

Molecular Formula: C10H14N5Na2O14P3

Molecular Weight: 567.14

Purity: ≥90% by HPLC

Appearance: White Powder

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Storage: Store at -20 °C

Melting Point: 180 °C

Boiling Point: 1028.3 °C at 760 mmHg

InChIKey: FIZIYLKEXVIRHJ-LGVAUZIVSA-L

Solubility: Soluble in Water

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)OP(=O)(O)[O-])O)O)N=C(NC2=O)N.[Na+].[Na+]

IUPAC Name: disodium;[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H16N5O14P3.2Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;/q;2*+1/p-2/t3-,5-,6-,9-;;/m1../s1

Synonyms: GTP-Na2; Guanosine 5'-(tetrahydrogen triphosphate) sodium salt (1:2); Guanosine 5'-(tetrahydrogen triphosphate) disodium salt; 5'-GTP disodium salt; Disodium 5'-GTP; Disodium guanosine triphosphate; GTP disodium salt; Guanosine 5'-triphosphoric acid disodium salt

Related CAS: 86-01-1 (free acid)

Uridine 5'-monophosphate

Description: Uridine 5'-Monophosphate, a nucleotide used as monomer in RNA. It is useful to the increasing uridine levels in blood.

CAT: BRP-00039

CAS: 58-97-9

Molecular Formula: C9H13N2O9P

Molecular Weight: 324.18

Purity: 96%

Appearance: White to Off-white Solid

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Storage: Store at 2-8°C

Density: 1.865±0.06 g/cm3

Melting Point: 202°C (dec.)

Boiling Point: 700.1±70.0 °C at 760 mmHg

InChIKey: DJJCXFVJDGTHFX-XVFCMESISA-N

Solubility: Soluble in Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

Synonyms: 5'-Uridylic Acid; Uridylic Acid; 5'-UMP; UMP; Uridine 5'-(Dihydrogen Phosphate); Uridine 5'-Phosphate; Uridine 5'-Phosphoric Acid; Uridine Monophosphate; Uridine Phosphate

Related CAS: 53624-79-6 (Deleted CAS) ; 81795-92-8 (Deleted CAS) ; 3387-36-8 (disodium salt) ; 3106-18-1 (monosodium salt) ; 681435-27-8 (disodium salt hydrate)

Inosine 5'-diphosphate disodium salt

Description: Inosine 5'-diphosphate disodium salt, a pivotal biochemical compound sought after in the biomedical industry, assumes an indispensable function in the generation and modulation of intracellular signaling molecules. Given its implication in cellular energy metabolism and nucleotide biosynthesis, this particular product finds application in ameliorating distinct metabolic disorders and neurodegenerative ailments.

CAT: BRP-00042

CAS: 54735-61-4

Molecular Formula: C10H12N4Na2O11P2

Molecular Weight: 472.15

Purity: 95%

Appearance: White to off-white powder

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Storage: Store at -20°C

Boiling Point: 925.2°C at 760 mmHg

InChIKey: MYSOKTVZCUBKOZ-IDIVVRGQSA-L

CanonicalSMILES: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+]

IUPAC Name: disodium;[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H14N4O11P2.2Na/c15-6-4(1-23-27(21,22)25-26(18,19)20)24-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,11,12,17)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

Synonyms: Inosine 5'-(trihydrogen diphosphate), disodium salt; IDP disodium salt; Inosine 5'-diphosphate sodium salt; Inosine 5'-(trihydrogen diphosphate), sodium salt (1:2)

Related CAS: 86-04-4 (free acid)

Inosine 5'-triphosphate trisodium salt

Description: Inosine-5'-triphosphate, an inosine nucleotide, is an intermediate in the purine metabolism pathway.

CAT: BRP-00043

CAS: 35908-31-7

Molecular Formula: C10H12N4O14P3.3Na

Molecular Weight: 574.11

Purity: ≥97% by HPLC

Appearance: White to Pale Yellow Solid

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Storage: Store at -20°C under inert atmosphere

Melting Point: >138°C (dec.)

InChIKey: QRGLCGLOQVQVCS-MSQVLRTGSA-K

Solubility: Soluble in Methanol (Very Slightly, Heated, Sonicated), Water (Slightly)

CanonicalSMILES: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]

IUPAC Name: trisodium;[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H15N4O14P3.3Na/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1

Synonyms: Inosine 5'-(Tetrahydrogen Triphosphate) Trisodium Salt; NSC 20266; Trisodium Inosine-5'-triphosphate; ITP; 9H-Purin-6-ol, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-, sodium salt (1:3); Trisodium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]inosine

Related CAS: 132-06-9 (free acid) ; 14356-95-7 (tetrasodium salt)

Adenosine 3',5'-Cyclic Monophosphate

Description: Adenosine 3',5'-Cyclic Monophosphate is an adenosine derivative with anticancer activity.

CAT: BRP-00047

CAS: 60-92-4

Molecular Formula: C10H12N5O6P

Molecular Weight: 329.21

Purity: ≥95%

Appearance: White Lyophilized Powder

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Storage: Store at -20°C

Density: 2.47±0.1 g/cm3 (Predicted)

Melting Point: 260°C (dec.)

Boiling Point: 701.5±70.0°C at 760 mmHg

InChIKey: IVOMOUWHDPKRLL-KQYNXXCUSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1C2C(C(C(O2)N3C=NC4=C3N=CN=C4N)O)OP(=O)(O1)O

IUPAC Name: (4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol

InChI: InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1

Synonyms: Cyclic AMP; cAMP; Adenosine 3',5'-cyclophosphate; 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-(6-amino-9H-purin-9-yl)tetrahydro-2-hydroxy-, 2-oxide, (4aR,6R,7R,7aS)-; cyclic Adenosine 3',5'-monophosphate

Related CAS: 37839-81-9 (monohydrochloride salt)

Bucladesine Sodium Salt

Description: DB-cAMP is a membrane-permeant activator of protein kinase A, the cAMP agonist.

CAT: BRP-00048

CAS: 16980-89-5

Molecular Formula: C18H23N5NaO8P

Molecular Weight: 491.37

Purity: ≥98% by HPLC

Appearance: White to Off-white Solid

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InChIKey: KRBZRVBLIUDQNG-JBVYASIDSA-M

CanonicalSMILES: CCCC(=O)NC1=NC=NC2=C1N=CN2C3C(C4C(O3)COP(=O)(O4)[O-])OC(=O)CCC.[Na+]

IUPAC Name: sodium;[(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] butanoate

InChI: InChI=1S/C18H24N5O8P.Na/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14;/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24);/q;+1/p-1/t10-,14-,15-,18-;/m1./s1

Synonyms: Adenosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, sodium salt (1:1); Butyramide, N-(9-β-D-ribofuranosyl-9H-purin-6-yl)-, cyclic hydrogen phosphate butyrate (ester), monosodium salt; Dibutyryl 3',5'-cyclic AMP sodium salt; Dibutyryl cyclic AMP monosodium salt; Dibutyryl cyclic AMP sodium salt; Dibutyryl-cAMP sodium salt; Monosodium dibutyryl cyclic AMP; N-6,O-2'-Dibutyryladenosine cyclic 3',5'-monophosphate sodium salt; N6,2'-O-Dibutyryl-3',5'-cyclic AMP sodium salt; N6,2'-O-Dibutyryladenosine-3',5'-monophosphate monosodium salt; N6,O2'-Dibutyryl-3',5'-cyclic AMP sodium salt; Sodium dibutyryl 3',5'-cyclic AMP; Sodium dibutyryl cAMP; Sodium N6,2'-O-dibutyryladenosine 3',5'-cyclic phosphate

Related CAS: 362-74-3 (free acid) ; 938448-87-4 (calcium salt)