What are nucleotides used for in molecular biology?

Nucleotides serve as substrates for enzymatic reactions such as DNA synthesis, RNA transcription, and IVT mRNA production.

What is the difference between dNTPs and NTPs?

dNTPs are used for DNA synthesis, while NTPs are used for RNA synthesis and transcription reactions.

Why is nucleotide purity important?

Impurities can inhibit enzyme activity and negatively affect reaction efficiency and fidelity.

Are nucleotides suitable for IVT mRNA synthesis?

Yes, high-purity NTPs are essential substrates for RNA polymerase-driven IVT mRNA workflows.

How does lot consistency affect nucleotide performance?

Consistent lot quality ensures reproducible enzymatic performance across repeated experiments and scale-up processes.

Nucleotides - RNA / BOC Sciences

UDP-D-glucose disodium salt

Description: UDP-D-glucose disodium salt is a phosphorylated uridine derivative used in nucleotide sugars metabolism as a substrate for the enzyme glucosyltransferases. It is used in the treatment of chronic alcoholism and in characterization of limonoid glucosyltransferase.

CAT: BRP-01644

CAS: 28053-08-9

Molecular Formula: C15H22N2Na2O17P2

Molecular Weight: 610.27

Purity: 98%

Appearance: White to Off-white Solid

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Storage: Store at -20°C under inert atmosphere

Melting Point: >162°C (dec.)

InChIKey: PKJQEQVCYGYYMM-QBNUFUENSA-L

Solubility: Soluble in Aqueous Acid (Slightly), Methanol (Slightly, Heated), Water (Sparingly, Sonicated)

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OC3C(C(C(C(O3)CO)O)O)O)O)O.[Na+].[Na+]

IUPAC Name: disodium;[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate

InChI: InChI=1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;/m1../s1

Synonyms: Uridine 5'-Diphosphoglucose Disodium Salt; Uridine 5'-(Trihydrogen diphosphate) P'-α-D-Glucopyranosyl Ester Disodium Salt; Uridine 5'-(Trihydrogen pyrophosphate) Mono-α-D-glucopyranosyl Ester Disodium Salt; Disodium UDP-glucose; Disodium Uridine Diphosphoglucose; UDP-a-D-glucose Disodium Salt

Related CAS: 133-89-1 (free acid) ; 117756-22-6 (β-isomer X sodium salt)

8-Bromo-cAMP sodium salt

Description: 8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA. It inhibits cell growth, decreases proliferation, increases differentiation and induces apoptosis.

CAT: BRP-01649

CAS: 76939-46-3

Molecular Formula: C10H10BrN5NaO6P

Molecular Weight: 430.08

Purity: 95%

Appearance: White to Off-white Solid

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Storage: Store at -20 °C

Melting Point: 233.9-235° C (dec.)

Shelf Life: 2 years if stored properly

InChIKey: DMRMZQATXPQOTP-GWTDSMLYSA-M

Solubility: Soluble in DMSO, Ethanol, Water

CanonicalSMILES: C1C2C(C(C(O2)N3C4=NC=NC(=C4N=C3Br)N)O)OP(=O)(O1)[O-].[Na+]

IUPAC Name: sodium;(4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol

InChI: InChI=1S/C10H11BrN5O6P.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

Synonyms: 8-Br-3',5'-cyclo-adenosine monophosphate, sodium salt; 8-Br-3',5'-cyclo-AMP.Na; (8Br-cAMP) sodium salt; 8-Bromo-adenosine-3',5'-cyclic monophosphate, Sodium salt; 8-Br-cAMP sodium salt; 8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt; Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate), sodium salt (1:1)

Related CAS: 23583-48-4 (free acid)

2'-O-Methyluridine-5'-triphosphate 100mM Sodium Solution

Description: 2'-O-Methyluridine-5'-triphosphate is a nucleotide analog commonly used in biochemistry research. It can be used as a substrate for RNA polymerases or as a terminoligical ATP analog for use in RNA synthesis reactions. Its effectiveness as an antiviral and antitumor agent is also being investigated.

CAT: BRP-01657

CAS: 143028-99-3

Molecular Formula: C10H17N2O15P3

Molecular Weight: 498.17

Purity: ≥97% by HPLC

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Storage: Store at -20 °C

Density: 2.0±0.1 g/cm3

InChIKey: BQJWHJWAEOHVCK-ZOQUXTDFSA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O

IUPAC Name: [[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H17N2O15P3/c1-23-8-7(14)5(25-9(8)12-3-2-6(13)11-10(12)15)4-24-29(19,20)27-30(21,22)26-28(16,17)18/h2-3,5,7-9,14H,4H2,1H3,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18)/t5-,7-,8-,9-/m1/s1

Synonyms: 2'-methoxy-UTP; 2'-O-Methyluridine 5'-triphosphoric acid; uridine 5'-(tetrahydrogen triphosphate), 2'-O-methyl-; 5'-(tetrahydrogen triphosphate), 2'-O-methyl-Uridine; 2'-O-Methyluridine 5'-(tetrahydrogen triphosphate); 2'-O-Me-UTP; 2'-OMe-UTP

2-Aminoadenosine-5'-Triphosphate 100mM Sodium Solution

Description: 2-Aminoadenosine-5'-Triphosphate, a versatile compound, finds extensive applications in enzymology and biotechnology as a substrate for kinases, ATPases, and nucleotide pyrophosphatases. Additionally, it is noteworthy for its ability to stimulate bone resorption activity in separated osteoclasts, therefore facilitating the study of bone metabolism and related diseases like osteoporosis and osteopenia.

CAT: BRP-01658

CAS: 18549-34-3

Molecular Formula: C10H17N6O13P3

Molecular Weight: 522.20

Purity: ≥90% by AX-HPLC

Appearance: Clear colorless to yellow liquid

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Storage: Store at -20°C

Density: 2.8±0.1 g/cm3

Boiling Point: 1045.8±75.0 °C at 760 mmHg

InChIKey: CABDYDUZLRXGTB-UUOKFMHZSA-N

CanonicalSMILES: C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N)N

IUPAC Name: [[(2R,3S,4R,5R)-5-(2,6-diaminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H17N6O13P3/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(18)5(17)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,17-18H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H4,11,12,14,15)/t3-,5-,6-,9-/m1/s1

Synonyms: 2-Amino-adenosine-5'-triphosphate; 2-NH2-ATP; 2-Amino-ATP; 2,6-Diaminopurine-ribose-5'-Triphosphate; DAP-rTP; 2-Aminoadenosine 5'-(tetrahydrogen triphosphate); 9H-Purine, 2,6-diamino-9-β-D-ribofuranosyl-, 5'-(tetrahydrogen triphosphate); 9H-Purine, 2,6-diamino-9-β-D-ribofuranosyl-, 5'-triphosphate; 2,6-Diaminopurine ribonucleoside triphosphate; 2,6-Diaminopurine riboside 5'-triphosphate; 2,6-Diaminopurine riboside triphosphate; 2,6-Diaminopurineribosyl-5'-triphosphate

2'-O-Methyladenosine-5'-triphosphate 100mM Sodium Solution

Description: 2'-O-Methyladenosine-5'-triphosphate, a pivotal compound within the realm of biomedicine, engenders cautious attention. Its versatility spans vast biomedical applications, including but not limited to the treatment of cancer, viral infections, and neurological disorders. This chemical entity's distinct molecular makeup renders it an auspicious instrument for refined therapeutic interventions. Consequently, the resolute exploration and multifarious prospects surrounding 2'-O-Methyladenosine-5'-triphosphate confer it profound significance within the dynamic milieu of the biomedical sector.

CAT: BRP-01719

CAS: 30948-06-2

Molecular Formula: C11H18N5O13P3

Molecular Weight: 521.21

Purity: ≥97% by HPLC

Appearance: Clear aqueous solution

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Storage: Store at -20 °C

Density: 2.4±0.1 g/cm3

Boiling Point: 907.0±75.0°C at 760 mmHg

InChIKey: OARVGPYQJRLYFE-IOSLPCCCSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O

IUPAC Name: [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C11H18N5O13P3/c1-25-8-7(17)5(2-26-31(21,22)29-32(23,24)28-30(18,19)20)27-11(8)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17H,2H2,1H3,(H,21,22)(H,23,24)(H2,12,13,14)(H2,18,19,20)/t5-,7-,8-,11-/m1/s1

Synonyms: 2'-O-Me-ATP; [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-methoxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate; Adenosine 5'-(tetrahydrogen triphosphate), 2'-O-Methyl-; 2'-O-Methyladenosine 5'-(tetrahydrogen triphosphate); 2'-O-Methyl-ATP; 2'-OMe-ATP

Related CAS: 100020-58-4 (tetrasodium salt) ; 100020-60-8 (TEA salt)

UDP-D-glucuronide trisodium salt

Description: UDP-D-glucuronide trisodium salt is a crucial compound used for drug metabolism studies. It acts as a donor molecule for the glucuronyl transferase enzyme, which helps in the biotransformation and detoxification of a wide range of drugs and endogenous compounds. This trisodium salt form facilitates stability and solubility, making it suitable for drug discovery and pharmacokinetic studies.

CAT: BRP-01741

CAS: 63700-19-6

Molecular Formula: C15H19N2Na3O18P2

Molecular Weight: 646.24

Purity: ≥97%

Appearance: White Powder

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InChIKey: XXXUNWUNTOMVIG-QWGSIYABSA-K

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OC3C(C(C(C(O3)C(=O)[O-])O)O)O)O)O.[Na+].[Na+].[Na+]

IUPAC Name: trisodium;(2S,3S,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl]oxy-3,4,5-trihydroxyoxane-2-carboxylate

InChI: InChI=1S/C15H22N2O18P2.3Na/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25;;;/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26);;;/q;3*+1/p-3/t4-,6-,7+,8+,9-,10-,11+,12-,14-;;;/m1.../s1

Synonyms: α-D-Glucopyranuronic acid, 1→P'-ester with uridine 5'-(trihydrogen diphosphate), sodium salt (1:3); UDPGA; UDPGA trisodium salt; α-D-Glucopyranuronic acid, 1→P'-ester with uridine 5'-(trihydrogen diphosphate), trisodium salt; Trisodium UDP-glucuronic acid; Uridine 5'-diphosphoglucuronic acid trisodium salt

Related CAS: 2616-64-0 (free acid)

Xanthosine 5'-monophosphate disodium salt

Description: Xanthosine is a guanosine derivative and has been found to be effective as a biomarker for detecting radiation exposure.

CAT: BRP-01829

CAS: 25899-70-1

Molecular Formula: C10H11N4Na2O9P

Molecular Weight: 408.17

Purity: ≥95% by HPLC

Appearance: White or off-white solid

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Storage: Store at 2-8 °C, under inert atmosphere

Melting Point: >116 °C (dec.)

InChIKey: QQPVYRBCIRHGSZ-LGVAUZIVSA-L

Solubility: Soluble in Water

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)([O-])[O-])O)O)NC(=O)NC2=O.[Na+].[Na+]

IUPAC Name: disodium;[(2R,3S,4R,5R)-5-(2,6-dioxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate

InChI: InChI=1S/C10H13N4O9P.2Na/c15-5-3(1-22-24(19,20)21)23-9(6(5)16)14-2-11-4-7(14)12-10(18)13-8(4)17;;/h2-3,5-6,9,15-16H,1H2,(H2,19,20,21)(H2,12,13,17,18);;/q;2*+1/p-2/t3-,5-,6-,9-;;/m1../s1

Synonyms: 5'-Xanthylic Acid Disodium Salt; Xmp Disodium salt; L-XMP Sodium; Disodium ((2R,3S,4R,5R)-5-(2,6-dihydroxy-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate; 5'-Xanthylic acid, sodium salt (1:2)

Related CAS: 523-98-8 (free acid)

5-Fluorouridine-5'-monophosphate sodium salt

Description: 5-fluorouridine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate having 5-fluorouracil as the pyrimidine component. It has a role as a drug metabolite. It is a pyrimidine ribonucleoside 5'-monophosphate and an organofluorine compound. It derives from a uridine 5'-monophosphate.

CAT: BRP-01840

CAS: 67550-10-1

Molecular Formula: C9H10FN2Na2O9P

Molecular Weight: 386.14

Purity: ≥97%

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InChIKey: MPRJYKKHPJYUND-HGXRYYEQSA-L

CanonicalSMILES: [Na].[Na].O=C1NC(=O)N(C=C1F)C2OC(COP(=O)(O)O)C(O)C2O

IUPAC Name: disodium;((2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate

InChI: InChI=1S/C9H12FN2O9P.2Na/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(21-8)2-20-22(17,18)19;;/h1,4-6,8,13-14H,2H2,(H,11,15,16)(H2,17,18,19);;/q;2*+1/p-2/t4-,5-,6-,8-;;/m1../s1

Synonyms: 5'-Uridylic acid, 5-fluoro-, disodium salt; 5F-UMP disodium salt; 5-Fluoro-5'-uridylic acid disodium salt; 5-Fluorouridine 5'-monophosphate disodium salt; 5-Fluorouridine 5'-phosphate disodium salt; 5-Fluorouridine monophosphate disodium salt; 5-Fluorouridylic acid disodium salt; 5-fluorouridine 5'-(dihydrogen phosphate) disodium salt; 5-Fluoro-UMP disodium salt

Related CAS: 796-66-7 (free acid)

2',3'-cGAMP

Description: 2',3'-cGAMP was considered to be the metazoan second messenger which is produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. It can activate innate immunity by directly binding the endoplasmic reticulum-resident receptor STING (stimulator of interferon genes).

CAT: BRP-01872

CAS: 1441190-66-4

Molecular Formula: C20H24N10O13P2

Molecular Weight: 674.41

Purity: ≥95%

Appearance: White solid

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Storage: Store at -20°C

Density: 2.61±0.1 g/cm3

Boiling Point: 1159.9±75.0°C at 760 mmHg

InChIKey: XRILCFTWUCUKJR-INFSMZHSSA-N

Solubility: Soluble in Water (50 mM)

CanonicalSMILES: C1C2C(C(C(O2)N3C=NC4=C3N=C(NC4=O)N)OP(=O)(OCC5C(C(C(O5)N6C=NC7=C(N=CN=C76)N)O)OP(=O)(O1)O)O)O

IUPAC Name: 2-amino-9-[(1R,6R,8R,9R,10S,15R,17R,18R)-8-(6-aminopurin-9-yl)-3,9,12,18-tetrahydroxy-3,12-dioxo-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.2.1.06,10]octadecan-17-yl]-1H-purin-6-one

InChI: InChI=1S/C20H24N10O13P2/c21-14-8-15(24-3-23-14)29(4-25-8)18-11(32)12-7(41-18)2-39-45(36,37)43-13-10(31)6(1-38-44(34,35)42-12)40-19(13)30-5-26-9-16(30)27-20(22)28-17(9)33/h3-7,10-13,18-19,31-32H,1-2H2,(H,34,35)(H,36,37)(H2,21,23,24)(H3,22,27,28,33)/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1

Synonyms: Cyclic [G(2',5')pA(3',5')p]; 2'-Guanylic acid, adenylyl-(3'→5')-, cyclic nucleotide; 2',3'-Cyclic guanosine adenosine monophosphate; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate; 2'-3'-cyclic GMP-AMP; cGAMP(2'→5'); c[G(2',5')pA(3',5')p]; Cyclic Gp(2'→5')Ap(3'→5')

Related CAS: 2734858-36-5 (disodium salt) ; 1637247-71-2 (Deleted CAS)

Udp-beta-L-rhamnose

Description: UDP-beta-L-rhamnose, an indispensable biomolecule extensively employed in the realm of biomedicine, assumes a pivotal stance in the intricate process of L-rhamnose biosynthesis. This saccharide, prevalent among diverse pharmaceutical agents and natural substances, acquires utmost significance in the advancement of therapeutics that aspire to combat bacterial infections, certain cancerous manifestations, and afflictions stemming from inflammation.

CAT: BRP-01886

CAS: 1955-26-6

Molecular Formula: C15H24N2O16P2

Molecular Weight: 550.30

Purity: 98%

Appearance: Clear colorless Liquid

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

Density: 1.90±0.1 g/cm3

InChIKey: DRDCJEIZVLVWNC-SLBWPEPYSA-N

CanonicalSMILES: CC1C(C(C(C(O1)OP(=O)(O)OP(=O)(O)OCC2C(C(C(O2)N3C=CC(=O)NC3=O)O)O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl] hydrogen phosphate

InChI: InChI=1S/C15H24N2O16P2/c1-5-8(19)10(21)12(23)14(30-5)32-35(27,28)33-34(25,26)29-4-6-9(20)11(22)13(31-6)17-3-2-7(18)16-15(17)24/h2-3,5-6,8-14,19-23H,4H2,1H3,(H,25,26)(H,27,28)(H,16,18,24)/t5-,6+,8-,9+,10+,11+,12+,13+,14+/m0/s1

Synonyms: Uridine 5'-(trihydrogen diphosphate), P'-(6-deoxy-β-L-mannopyranosyl) ester; Uridine 5'-(trihydrogen pyrophosphate), mono(6-deoxy-β-L-mannopyranosyl) ester; Uridine 5'-pyrophosphate, β-L-rhamnopyranosyl ester; UDP-β-rhamnose; UDP-L-rhamnose; UDP-rhamnose; UDP-β-L-rhamnose; Uridine 5'-(trihydrogen pyrophosphate), mono(6-deoxy-L-mannopyranosyl) ester; Uridine 5'-diphosphate rhamnose; Uridine diphosphate rhamnose; Uridine diphosphorhamnose

Related CAS: 13094-63-8 (Deleted CAS) ; 19253-25-9 (Deleted CAS) ; 98168-36-6 (Deleted CAS) ; 909887-67-8 (Deleted CAS)

UDP-N-acetyl-D-galactosamine disodium salt

Description: UDP-N-acetyl-D-galactosamine disodium salt is a nucleotide sugar used by glycosyltransferases to transfer N-acetylgalactosamine residues to substrates. UDP-N-acetyl-D-galactosamine disodium salt is an essential biochemical reagent used in the study and application of glycosylation processes. Its role as a glycosyl donor in the biosynthesis of glycoproteins and glycolipids makes it a valuable tool in biochemical research, particularly in understanding cellular functions and developing therapeutic strategies for glycosylation-related disorders.

CAT: BRP-01887

CAS: 108320-87-2

Molecular Formula: C17H25N3Na2O17P2

Molecular Weight: 651.32

Purity: ≥95%

Appearance: White Solid

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

InChIKey: HXWKMJZFIJNGES-AMMUOFBGSA-L

Solubility: Soluble in Water

CanonicalSMILES: CC(=O)NC1C(C(C(OC1OP(=O)([O-])OP(=O)([O-])OCC2C(C(C(O2)N3C=CC(=O)NC3=O)O)O)CO)O)O.[Na+].[Na+]

IUPAC Name: disodium;[(2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl] [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate

InChI: InChI=1S/C17H27N3O17P2.2Na/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28;;/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28);;/q;2*+1/p-2/t7-,8-,10-,11+,12-,13-,14-,15-,16-;;/m1../s1

Synonyms: UDP-a-N-acetyl-D-galactosamine Disodium Salt; Uridine 5'-diphospho-N-acetylgalactosamine disodium salt; 2-Acetamido-2-deoxy-a-D-galactopyranosyl uridine diphosphate disodium salt; Uridine 5'-(trihydrogen diphosphate) P'-[2-(acetylamino)-2-deoxy-alpha-D-galactopyranosyl] ester disodium

Related CAS: 7277-98-7 (free acid)

2-Thio-UTP tetrasodium salt

Description: 2-ThioUTP tetrasodium salt is a potent and selective P2Y2 agonist (EC50 = 0.035, 0.35 and 1.5 μM for hP2Y2, hP2Y4 and hP2Y6 receptors, respectively).

CAT: BRP-01890

CAS: 1343364-70-4

Molecular Formula: C9H11N2Na4O14P3S

Molecular Weight: 588.13

Purity: ≥95%

Appearance: Colorless transparent liquid

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Storage: Store at -20°C

InChIKey: QCBCNKBBEOQRRB-ODQFIEKDSA-J

Solubility: Soluble in Water

CanonicalSMILES: C1=CN(C(=S)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])O)O.[Na+].[Na+].[Na+].[Na+]

IUPAC Name: tetrasodium;[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate

InChI: InChI=1S/C9H15N2O14P3S.4Na/c12-5-1-2-11(9(29)10-5)8-7(14)6(13)4(23-8)3-22-27(18,19)25-28(20,21)24-26(15,16)17;;;;/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,20,21)(H,10,12,29)(H2,15,16,17);;;;/q;4*+1/p-4/t4-,6-,7-,8-;;;;/m1..../s1

Synonyms: 2-Thiouridine 5'-triphosphate tetrasodium salt; 2-Thiouridine 5'-(tetrahydrogen triphosphate) tetrasodium salt; ((2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate tetrasodium salt; Uridine 5'-(tetrahydrogen triphosphate), 2-thio-, sodium salt (1:4)

Related CAS: 35763-29-2 (free acid)

PSI 7411

Description: An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir.

CAT: BRP-02022

CAS: 1015073-43-4

Molecular Formula: C10H14FN2O8P

Molecular Weight: 340.20

Purity: ≥95%

Appearance: White Solid

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10 mg	$519	In stock
50 mg	$999	In stock

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Storage: Store at 2-8 °C, protect from light

Density: 1.73±0.1 g/cm3(Predicted)

InChIKey: JAJZLQMRDFLNSW-VPCXQMTMSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: CC1(C(C(OC1N2C=CC(=O)NC2=O)COP(=O)(O)O)O)F

IUPAC Name: [(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C10H14FN2O8P/c1-10(11)7(15)5(4-20-22(17,18)19)21-8(10)13-3-2-6(14)12-9(13)16/h2-3,5,7-8,15H,4H2,1H3,(H,12,14,16)(H2,17,18,19)/t5-,7-,8-,10-/m1/s1

Synonyms: 5'-Uridylic acid, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)-; (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic acid; PSI-7411; PSI7411; 2'-Fluoro-2'-methyl(up)-uridine-5'-monophosphate; 2'-F-2'-Me(up)-UMP; Sofosbuvir Impurity 34 (GS-606965)

N1-Methyl ATP

Description: N1-Methyl-ATP, shining like a star in the biomedical industry, plays a critical role in the study of pleiotropic purinergic signaling. Known to be a potent P2X receptor antagonist and a P2Y receptor modulator, this versatile nucleotide derivative has demonstrated its impressive effects in vasodilation, immune cell regulation, and beyond. Interestingly, evidence suggests that N1-Methyl-ATP may also possess therapeutic potential in addressing various human maladies, ranging from cardiovascular disorders to the most dreaded neurodegenerative diseases.

CAT: BRP-00001

CAS: 68643-11-8

Molecular Formula: C11H18N5O13P3

Molecular Weight: 521.21

Purity: ≥95% by HPLC

Appearance: White to off-white solid

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Storage: Store at -20 °C

Density: 2.4±0.1 g/cm3

Boiling Point: 933.1±75.0 °C at 760 mmHg

InChIKey: QTWNSBVFPSAMPO-IOSLPCCCSA-N

CanonicalSMILES: CN1C=NC2=C(C1=N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-imino-1-methylpurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C11H18N5O13P3/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(18)7(17)5(27-11)2-26-31(22,23)29-32(24,25)28-30(19,20)21/h3-5,7-8,11-12,17-18H,2H2,1H3,(H,22,23)(H,24,25)(H2,19,20,21)/t5-,7-,8-,11-/m1/s1

Synonyms: m1A; N1-Methyl-ATP; 1-Methyladenosine 5'-(tetrahydrogen triphosphate); 1-Methyladenosine 5'-triphosphate; N1-Methyladenosine-5'-Triphosphate

Related CAS: 1026128-10-8 (tetrasodium salt)

N6-Methyl ATP

Description: N6-Methyl-ATP, a base modified analog of adenosine, is able to substitute for ATP in some biological systems. Besides, N6-Methyl-ATP is a potent agonist for P2Y-purinoceptors in the guinea pig, taenia coli.

CAT: BRP-00002

CAS: 3130-39-0

Molecular Formula: C11H18N5O13P3

Molecular Weight: 521.21

Purity: ≥95% by HPLC

Appearance: Colorless to slightly yellow liquid

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Storage: Store at -20 °C

Density: 2.4±0.1 g/cm3

Boiling Point: 927.9±75.0 °C at 760 mmHg

InChIKey: LCQWKKZWHQFOAH-IOSLPCCCSA-N

CanonicalSMILES: CNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C11H18N5O13P3/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(18)7(17)5(27-11)2-26-31(22,23)29-32(24,25)28-30(19,20)21/h3-5,7-8,11,17-18H,2H2,1H3,(H,22,23)(H,24,25)(H,12,13,14)(H2,19,20,21)/t5-,7-,8-,11-/m1/s1

Synonyms: m6A; N6-Methyladenosine-5'-Triphosphate; m6ATP; Adenosine, N-methyl-, 5'-(tetrahydrogen triphosphate); Adenosine, N-methyl-, 5'-triphosphate; N-Methyladenosine 5'-(tetrahydrogen triphosphate); 6-N-Methyladenosine 5'-triphosphate; N6-Methyl-ATP; N6-Monomethyladenosine 5'-triphosphate

Related CAS: 35892-91-2 (tetrasodium salt) ; 154962-75-1 (triammonium salt) ; 1226907-41-0 (tetraammonium salt)

5-Methylcytidine 5'-triphosphate

Description: 5-Methyl-CTP is a derivative of Cytidine, which is found in ribonucleic acids of animals, plants and bacteria. 5-Methyl-CTP in liver emulsion can inhibit the growth of spontaneous tumors of mammary gland origin in mice.

CAT: BRP-00003

CAS: 327174-86-7

Molecular Formula: C10H18N3O14P3

Molecular Weight: 497.18

Purity: ≥95% by HPLC

Appearance: clear aqueous solution

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Storage: Store at -20 °C

Density: 2.39±0.1 g/cm3

Boiling Point: 838.2±75.0 °C

Application: 5-Methyl-CTP is a derivative of Cytidine.

InChIKey: YIJVOACVHQZMKI-JXOAFFINSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H18N3O14P3/c1-4-2-13(10(16)12-8(4)11)9-7(15)6(14)5(25-9)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5-7,9,14-15H,3H2,1H3,(H,20,21)(H,22,23)(H2,11,12,16)(H2,17,18,19)/t5-,6-,7-,9-/m1/s1

Synonyms: m5C; 5-methyl-CTP; 5-Methylcytidine 5'-triphosphoric acid; Cytidine 5'-(tetrahydrogentriphosphate), 5-Methyl-; 5-Methylcytidine 5'-(tetrahydrogentriphosphate); m5CTP; 5-Me-CTP; 5-Methyl CTP; 5mCTP

5-hme-CTP

Description: 5-hme-CTP, a nucleotide analog, has been found to selectively activate purinergic P2Y1 receptors, thereby enhancing biomedical research efforts aimed at uncovering cellular signaling pathways relevant to diverse biological phenomena such as platelet activation. Given its multifaceted role, it comes as no surprise that beyond being a great tool for scientific inquiry, 5-hme-CTP holds great potential for therapeutic interventions in diseases associated with compromised cellular function, such as stroke, multiple sclerosis, and Alzheimer's disease.

CAT: BRP-00004

CAS: 39749-90-1

Molecular Formula: C10H18N3O15P3

Molecular Weight: 513.18

Purity: ≥90% by AX-HPLC

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Storage: Store at -20°C

Density: 2.49±0.1 g/cm3

Boiling Point: 906.3±75.0 °C at 760 mmHg

InChIKey: NAOOSVVUTFPWHI-JXOAFFINSA-N

CanonicalSMILES: C1=C(C(=NC(=O)N1C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N)CO

IUPAC Name: [[(2R,3S,4R,5R)-5-[4-amino-5-(hydroxymethyl)-2-oxopyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H18N3O15P3/c11-8-4(2-14)1-13(10(17)12-8)9-7(16)6(15)5(26-9)3-25-30(21,22)28-31(23,24)27-29(18,19)20/h1,5-7,9,14-16H,2-3H2,(H,21,22)(H,23,24)(H2,11,12,17)(H2,18,19,20)/t5-,6-,7-,9-/m1/s1

Synonyms: hm5C; 5-Hydroxymethylcytidine-5'-Triphosphate; 5-hm-CTP; 5-HmCTP; 5-Hydroxymethyl-CTP; 5-(Hydroxymethyl)cytidine 5'-triphosphoric acid; 5-Hydroxymethyl CTP; 5-(Hydroxymethyl)cytidine 5'-(tetrahydrogen triphosphate); 5-(Hydroxymethyl)-CTP; 5-(Hydroxymethyl)cytidine 5'-triphosphate

Related CAS: 1613529-96-6 (triethylamine salt)

7-Methyl-GTP inner salt

Description: m7GTP, the nucleoside triphosphate that has a critical role in RNA synthesis and gene expression regulation, is also attributed with virus fighting capabilities and cancer cell apoptosis induction. With its dual functions as a precursor and modifier in RNA synthesis and as an inhibitor in viral infections, m7GTP shows promise in the treatment of diseases such as cancer.

CAT: BRP-00005

CAS: 26554-26-7

Molecular Formula: C11H18N5O14P3

Molecular Weight: 537.21

Purity: ≥95% by HPLC

Appearance: clear aqueous solution

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InChIKey: DKVRNHPCAOHRSI-KQYNXXCUSA-N

CanonicalSMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [hydroxy(phosphonooxy)phosphoryl] phosphate

InChI: InChI=1S/C11H18N5O14P3/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(28-10)2-27-32(23,24)30-33(25,26)29-31(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H6-,12,13,14,19,20,21,22,23,24,25,26)/t4-,6-,7-,10-/m1/s1

Synonyms: Guanosine 5'-(tetrahydrogen triphosphate), 7-methyl-, inner salt; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-, inner salt; Purinium, 2-amino-1,6-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-, hydroxide, 5'-(tetrahydrogen triphosphate), inner salt; 7-Methylguanosine 5'-triphosphate inner salt; m7GTP inner salt; 7-methylguanosine triphosphate inner salt

Related CAS: 104809-18-9 (disodium salt) ; 114409-96-0 (triethylamine salt (1:3)) ; 88106-66-5 (triethylamine salt (1:1))

2-Thio-UTP

Description: 2-Thio-UTP is a potent and selective agonist of P2Y2 receptor (EC50 = 0.035 μM).

CAT: BRP-00006

CAS: 35763-29-2

Molecular Formula: C9H15N2O14P3S

Molecular Weight: 500.21

Purity: ≥95%

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Storage: Store at -20°C

Density: 2.09±0.1 g/cm3

InChIKey: KHYOUGAATNYCAZ-XVFCMESISA-N

CanonicalSMILES: C1=CN(C(=S)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(29)10-5)8-7(14)6(13)4(23-8)3-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,20,21)(H,10,12,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1

Synonyms: Uridine 5'-(tetrahydrogen triphosphate), 2-thio-; 2-Thiouridine 5'-(tetrahydrogen triphosphate); 2-Thiouridine 5'-triphosphate; ((2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 2-thioUTP; 1-[5-O-(Hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-β-D-ribofuranosyl]-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 2-thio-1-β-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-triphosphate

Related CAS: 1343364-70-4 (tetrasodium salt)

PseudoUridine 5'-Triphosphate

Description: PseudoUridine 5'-Triphosphate is a modified nucleoside used for the polymerase-mediated synthesis of RNA molecules. The sodium salt form PseudoUridine 5'-Triphosphate Sodium (B2706-358098) is in stock.

CAT: BRP-00007

CAS: 1175-34-4

Molecular Formula: C9H15N2O15P3

Molecular Weight: 484.14

Purity: ≥95% by HPLC

Appearance: clear aqueous solution

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Storage: Storage at -20°C

Density: 2.079±0.06 g/cm3

InChIKey: VEWJOCYCKIZKKV-GBNDHIKLSA-N

CanonicalSMILES: C1=C(C(=O)NC(=O)N1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5S)-5-(2,4-dioxo-1H-pyrimidin-5-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H15N2O15P3/c12-5-4(2-23-28(19,20)26-29(21,22)25-27(16,17)18)24-7(6(5)13)3-1-10-9(15)11-8(3)14/h1,4-7,12-13H,2H2,(H,19,20)(H,21,22)(H2,16,17,18)(H2,10,11,14,15)/t4-,5-,6-,7+/m1/s1

Synonyms: Ψ; Pseudo-UTP; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-2,4(1H,3H)pyrimidinedione; 5-β-D-Ribofuranosyluracil 5'-Triphosphate; Pseudouridine Triphosphate; Pseudo UTP; pUTP

Related CAS: 28022-82-4 (tetrasodium salt)