Nucleotides - RNA / BOC Sciences

3'-O-Methyl-5'-guanylic acid

Description: 3’-O-Methyl-5’-guanylic acid is a pivotal molecule extensively employed in the realm of compound is assuming an eminent position in the research and development of sundry pharmaceutical agents and investigations concerning RNA and DNA architectures.

CAT: BRP-01891

CAS: 400806-41-9

MF: C11H16N5O8P

MF: 377.25

Purity: ≥98%

Appearance: White solid

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

Density: 2.20±0.1 g/cm3

Boiling Point: 828.8±75.0 °C at 760 mmHg

InChIKey: JGYKGFFURACNNS-KQYNXXCUSA-N

CanonicalSMILES: COC1C(OC(C1O)N2C=NC3=C2N=C(NC3=O)N)COP(=O)(O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-3-methoxyoxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C11H16N5O8P/c1-22-7-4(2-23-25(19,20)21)24-10(6(7)17)16-3-13-5-8(16)14-11(12)15-9(5)18/h3-4,6-7,10,17H,2H2,1H3,(H2,19,20,21)(H3,12,14,15,18)/t4-,6-,7-,10-/m1/s1

Synonyms: 3'-OMe-GMP; 3'-O-Methylguanosine-5'-Monophosphate; 3'-O-Methylguanosine 5'-phosphate; 3'-O-Methylguanosine 5'-(dihydrogen phosphate); ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)methyl dihydrogen phosphate

m7GDP

Description: m7GDP is an esteemed compound commodity widely employed within the biomedical realm, epitomizes an indispensable medium in sundry enzymatic reactions, exerting a momentous influence on the intricate processes of RNA transcription and translation. Its invaluable utility extends to the research of viral afflictions, notably influenza and respiratory syncytial virus (RSV). Additionally, it facilitates meticulous investigations pertaining to mRNA processing and the cap-dependent translation mechanism.

CAT: BRP-01892

CAS: 117723-13-4

MF: C11H18N5O11P2

MF: 458.24

Purity: 95%

Appearance: White solid

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

InChIKey: SBASPRRECYVBRF-KQYNXXCUSA-O

CanonicalSMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate

InChI: InChI=1S/C11H17N5O11P2/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24)/p+1/t4-,6-,7-,10-/m1/s1

Synonyms: 7-methyl-7,8-dihydroguanosine-5'-diphosphate; 7-methylguanosine diphosphate; N7-methyl-GDP; 7-Methyl-Guanosine-5'-Diphosphate; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy(phosphonooxy)phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-; 7-Methylguanosine 5'-(trihydrogen diphosphate); 7-Methyl-GDP; 7-Methylguanosine 5'-diphosphate; 7-methylguanosine 5'-diphosphate(1+); N7-methylguanosine 5'-diphosphate

Related CAS: 444081-81-6 (Deleted CAS) ; 26467-11-8 (inner salt) ; 852155-74-9 (TEA salt (1:3))

7-Methylguanosine 5'-diphosphate TEA salt

Description: m7GDP TEA salt, a derivative nucleoside, bears significant implications in the study of RNA capping. Notably, it partakes in the capping of mRNA during transcription and substantiates an inhibitory effect against viral infections, such as Flavivirus, rendering it an invaluable research asset.

CAT: BRP-01893

CAS: 240137-50-2

MF: C11H17N5O11P2.xC6H15N

MF: 457.23 (free acid)

Purity: ≥95% by HPLC

Appearance: clear aqueous solution

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono phosphate;N,N-diethylethanamine

Synonyms: Guanosine 5'-(trihydrogen diphosphate), 7-methyl-, inner salt, compd. with N,N-diethylethanamine (1:x); m7GDP TEA salt; 7-Methyl-guanosine-5'-diphosphate TEA salt; 7-Methyl-GDP TEA salt; 7-Methylguanosine diphosphate TEA salt; N7-Methyl-GDP TEA salt

Related CAS: 26467-11-8 (free acid) ; 104809-16-7 (sodium salt)

7-Methylguanosine 5'-diphosphate sodium

Description: 7-Methylguanosine 5'-diphosphate sodium is a pivotal biomolecular recompound assuming a critical function as a substrate stimulus for catalytic enzymes engaged in RNA bioresearch and development. Simultaneously, it exerts influential control over intricate cellular mechanisms encompassing gene expression modulation and cell signaling orchestration.

CAT: BRP-01894

CAS: 104809-16-7

MF: C11H16N5NaO11P2

MF: 479.21

Purity: ≥95% by HPLC

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

InChIKey: GWXMULHRNCYTBF-MCDZGGTQSA-M

CanonicalSMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+]

IUPAC Name: sodium;[[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C11H17N5O11P2.Na/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22;/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1

Synonyms: Guanosine 5'-(trihydrogen diphosphate), 7-methyl-, inner salt, compd. with sodium salt(1:1); m7GDP sodium salt; 7-Methyl-guanosine-5'-diphosphate sodium salt; 7-Methyl-GDP sodium salt; 7-Methylguanosine diphosphate sodium salt; N7-Methyl-GDP sodium salt; 7-Methylguanosine 5'-diphosphate monosodium salt; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy(phosphonooxy)phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-, inner salt, monosodium salt

Related CAS: 26467-11-8 (free acid)

7-Methylguanosine 5-disphosphoimidazolide disodium

Description: 7-Methylguanosine 5-disphosphoimidazolide disodium is an impurity of Guanosine. Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.

CAT: BRP-01895

CAS: 852155-68-1

MF: C14H18N7Na2O10P2

MF: 552.27

Purity: ≥98%

Appearance: Yellow solid

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

InChIKey: DLFOIRRSTNECTJ-BJSVFJQSSA-M

CanonicalSMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)(N4C=CN=C4)[O-])O)O.[Na+].[Na+]

IUPAC Name: disodium;[[(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-imidazol-1-ylphosphinate

InChI: InChI=1S/C14H19N7O10P2.2Na/c1-19-6-21(11-8(19)12(24)18-14(15)17-11)13-10(23)9(22)7(30-13)4-29-33(27,28)31-32(25,26)20-3-2-16-5-20;;/h2-3,5-7,9-10,13,22-23H,4H2,1H3,(H4-,15,17,18,24,25,26,27,28);;/q;2*+1/p-1/t7-,9-,10-,13-;;/m1../s1

Synonyms: 5'-Guanylic acid, 7-methyl-, monoanhydride with 1H-imidazol-1-ylphosphonic acid, disodium salt; Guanosine Impurity 4 Disodium Salt; 5'-Guanylic acid, 7-methyl-, monoanhydride with 1H-imidazol-1-ylphosphonic acid, sodium salt (1:2)

Related CAS: 852282-35-0 (free acid) ; 531553-69-2 (free acid inner salt)

Adenosine 5'-monophosphate sodium salt

Description: Adenosine 5'-monophosphate sodium salt is a vital compound acting as a precursor to ATP is an essential energy source in cells. This compound plays a crucial role in research of cellular metabolism, gene expression and neurotransmission.

CAT: BRP-01901

CAS: 13474-03-8

MF: C10H14N5O7P.xNa

MF: 347.22 (free acid)

Purity: 98%

Appearance: White powder

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Storage: Store at -20°C

InChIKey: FYWLYWMEGHCZAX-MCDZGGTQSA-M

Solubility: Soluble in Water, Dimethyl Sulfoxide, Methanol

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)[O-])O)O)N.[Na+]

InChI: InChI=1S/C10H14N5O7P.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1

Synonyms: 5'-Adenylic acid, sodium salt (1:x); 5'-Adenylic acid, sodium salt; 5'-AMP sodium salt; AMP sodium salt; Sodium adenosine-5'-monophosphate; Sodium AMP; Adenosine 5'-(dihydrogen phosphate) sodium salt; Adenosine 5'-phosphate sodium salt; Adenosine 5'-phosphoric acid sodium salt; Adenosine monophosphate sodium salt

Related CAS: 61-19-8 (free acid) ; 132-00-3 (monosodium salt) ; 4578-31-8 (disodium salt) ; 1193174-04-7 (tetrasodium salt)

5'-Uridylic acid disodium salt hydrate

Description: 5'-Uridylic acid disodium salt hydrate is a key component for RNA synthesis, while also serving as a top-rated dietary supplement that effectively boosts immune function and reduces inflammation. As if its unrivaled use wasn't enough, it has additionally exhibited remarkable therapeutic potential in treating Hepatitis and liver diseases, making it a must-have in any scientific lab or healthcare setting.

CAT: BRP-01905

CAS: 681435-27-8

MF: C9H11N2Na2O9P.xH2O

MF: 368.14 (anhydrous basis)

Purity: 97%

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Storage: Store at 2-8 °C, sealed storage, away from moisture

Melting Point: 208 °C

InChIKey: DXOORDQZBSXBBP-LLWADOMFSA-L

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])[O-])O)O.O.[Na+].[Na+]

IUPAC Name: disodium;[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate;hydrate

InChI: InChI=1S/C9H13N2O9P.2Na.H2O/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t4-,6-,7-,8-;;;/m1.../s1

Synonyms: 5'-Uridylic acid, sodium salt, hydrate (1:2:x); Uridine 5'-monophosphate disodium salt hydrate; Uridylic acid disodium salt hydrate; 5'-UMP disodium salt hydrate; UMP disodium salt hydrate; Uridine 5'-(dihydrogen phosphate) disodium salt hydrate; Uridine 5'-phosphate disodium salt hydrate; Uridine 5'-phosphoric acid disodium salt hydrate; Uridine monophosphate disodium salt hydrate; Uridine phosphate disodium salt hydrate

Related CAS: 3387-36-8 (anhydrous) ; 58-97-9 (anhydrous free acid)

Fludarabine Phosphate

Description: Fludarabine phosphate is an important chemotherapeutic agent used to treat certain types of leukemia and lymphoma. Its ability to interfere with DNA synthesis and induce apoptosis makes it effective in targeting rapidly dividing malignant cells. While it has significant therapeutic benefits, its use is associated with various side effects that require careful management during treatment.

CAT: BRP-01920

CAS: 75607-67-9

MF: C10H13FN5O7P

MF: 365.21

Purity: ≥98% by HPLC

Appearance: White Powder

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Storage: Store at -20°C under inert atmosphere

Density: 2.39±0.1 g/cm3 (Predicted)

Melting Point: >193°C (dec.)

Boiling Point: 864.2±75.0 °C at 760 mmHg

Application: Antimetabolites, Antineoplastic

InChIKey: GIUYCYHIANZCFB-FJFJXFQQSA-N

Solubility: Soluble in Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)O)O)O)N=C(N=C2N)F

IUPAC Name: [(2R,3S,4S,5R)-5-(6-amino-2-fluoropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C10H13FN5O7P/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,17-18H,1H2,(H2,12,14,15)(H2,19,20,21)/t3-,5-,6+,9-/m1/s1

Synonyms: Fludarabine 5'-monophosphate; 2-Fluoro-ARA AMP; Fludarabine monophosphate; FAMP; NSC-312887; 2-Fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine; 2-Fluoroadenine arabinoside 5'-monophosphate; ((2R,3S,4S,5R)-5-(6-amino-2-fluoro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate; 9-beta-Arabinofuranosyl-2-fluoroadenine-5'-phosphate

Related CAS: 21679-14-1 (Fludarabine)

Adenosine 5'-monophosphate sodium salt hydrate

Description: Adenosine 5'-monophosphate sodium salt hydrate is a paramount compound harnessed in the research of varied maladies encompassing asthma, chronic obstructive pulmonary disease (COPD) and cardiac arrhythmias. It meticulously modulates intricate cellular signaling cascades facilitating bronchodilation and studying inflammation.

CAT: BRP-01925

CAS: 149022-20-8

MF: C10H14N5O7P.xH2O.xNa

MF: 347.22 (anhydrous basis)

Purity: 98%

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Storage: Store at -20°C

IUPAC Name: Sodium;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate;hydrate

Synonyms: 5'-Adenylic acid, sodium salt, hydrate (1:x:x); 5'-AMP sodium salt hydrate; AMP sodium salt hydrate; Sodium adenosine-5'-monophosphate hydrate; Sodium AMP hydrate

Related CAS: 13474-03-8 (anhydrous) ; 61-19-8 (anhydrous free acid)

3-Acetylpyridine adenine dinucleotide

Description: 3-Acetylpyridine adenine dinucleotide is a pivotal cofactor in metabolic regulation, exhibiting intricate involvement in diverse biological reactions. Its functionality as an electron carrier fortifies numerous enzymatic reactions, facilitating the intercellular transfer of energy and electrons. Consequently, the compound assuming a vital role in cellular respiration and ATP research and development. Moreover, its application encompasses the exploration of cellular redox reactions, energy transfer mechanisms, in addition to studying a plethora of ailments and pharmaceutical developments.

CAT: BRP-01936

CAS: 86-08-8

MF: C22H28N6O14P2

MF: 662.44

Purity: 92%

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InChIKey: KPVQNXLUPNWQHM-RBEMOOQDSA-N

CanonicalSMILES: CC(=O)C1=C[N+](=CC=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(3-acetylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphate

InChI: InChI=1S/C22H28N6O14P2/c1-10(29)11-3-2-4-27(5-11)21-17(32)15(30)12(40-21)6-38-43(34,35)42-44(36,37)39-7-13-16(31)18(33)22(41-13)28-9-26-14-19(23)24-8-25-20(14)28/h2-5,8-9,12-13,15-18,21-22,30-33H,6-7H2,1H3,(H3-,23,24,25,34,35,36,37)/t12-,13-,15-,16-,17-,18-,21-,22-/m1/s1

Synonyms: APAD; Acetylpyridine adenine dinucleotide; Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-acetyl-1-β-D-ribofuranosylpyridinium, inner salt; 3-Acetyl-1-β-D-ribofuranosylpyridinium hydroxide, 5'-ester with adenosine 5'-diphosphate, inner salt; Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-acetyl-1-β-D-ribofuranosylpyridinium hydroxide, inner salt; Adenosine 5'-(trihydrogen pyrophosphate), 5'→5'-ester with 3-acetyl-1-β-D-ribofuranosylpyridinium hydroxide, inner salt; Pyridinium, 3-acetyl-1-β-D-ribofuranosyl-, hydroxide, 5'→5'-ester with adenosine 5'-(trihydrogen pyrophosphate), inner salt; 3-Acetyl NAD; 3-Acetylpyridine NAD; Diphosphopyridine nucleotide, 1-(3-pyridinyl)ethanone analog; Nicotinamide acetylpyridine dinucleotide; Nicotinamide-adenine dinucleotide, 3-acetyl analog; NSC 20275; Reduced acetylpyridine adenine dinucleotide

5'-Inosinic Acid Disodium Salt Hydrate

Description: 5'-Inosinic Acid Disodium Salt Hydrate, a quintessential biochemical reagent employed in the pharmaceutical industry, has been deployed to cure a myriad of afflictions such as gout, arthritis and hyperuricemia while simultaneously doubling up as a flavor enhancer in the world of food and beverage.

CAT: BRP-01943

CAS: 352195-40-5

MF: C10H11N4Na2O8P.xH2O

MF: 392.17 (anhydrous basis)

Purity: 97%

Appearance: White to Off-White Powder

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Storage: Store at 2-8 °C, sealed storage, away from moisture

Melting Point: 175 °C

InChIKey: KQCIGEIXDXQSGM-MSQVLRTGSA-L

CanonicalSMILES: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)([O-])[O-])O)O.O.[Na+].[Na+]

IUPAC Name: disodium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl phosphate;hydrate

InChI: InChI=1S/C10H13N4O8P.2Na.H2O/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

Synonyms: 5'-Inosinic acid, sodium salt, hydrate (1:2:x); 5'-Inosinic acid, disodium salt, hydrate; Sodium 5'-inosinate hydrate (2:1:x); Inosinic-5'-disodium phosphate hydrate; Disodium 5'-inosinate hydrate

Related CAS: 20813-76-7 (disodium octahydrate) ; 131-99-7 (free acid anhydrous)

Inosine 5'-monophosphate

Description: Inosine 5'-monophosphate (IMP) is a profound molecular compound magnanimously entrusted with the profound responsibility of studying an extensive array of afflictions, encompassing neurologic dysfunctions, cardiac anomalies and immunological imperfections.

CAT: BRP-01944

CAS: 131-99-7

MF: C10H13N4O8P

MF: 348.20

Purity: ≥98%

Appearance: Odourless, colourless or white crystals or powder

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Storage: Store at -20 °C

Density: 2.31±0.10 g/cm3

Boiling Point: 851.4 °C at 760 mmHg

Flash Point: 468.7°C

InChIKey: GRSZFWQUAKGDAV-KQYNXXCUSA-N

Solubility: Soluble in Ethanol (Slightly), Water (Freely)

CanonicalSMILES: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

Synonyms: Inosinic acid; IMP; 1-5'-P; Inosinemonophosphate; 5'-Inosinic acid; 5'-IMP; CJ-TIDE IMP; Inosine 5'-(dihydrogen phosphate); Inosine 5'-phosphate; Inosine-5'-monophosphoric acid; TIDE IMP; ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate

Related CAS: 4691-65-0 (disodium salt) ; 352195-40-5 (disodium salt x-hydrate) ; 20813-76-7 (disodium salt octahydrate)

2-Cyanoethyl 2-propen-1-yl 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(dimethylamino)methylene]-3'-guanylate

Description: 2-Cyanoethyl 2-propen-1-yl 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(dimethylamino)methylene]-3'-guanylate is a noteworthy compound with diverse application in biomedical research. Notably, this synthetic nucleotide analog has demonstrated efficacy in treating viral infections, including HIV and hepatitis. Researchers have also utilized this compound in oligonucleotide synthesis for genetic engineering applications. Interestingly, this multifaceted compound shows great promise as a key player in gene therapy research.

CAT: BRP-01951

CAS: 827602-96-0

MF: C25H40N7O8PSi

MF: 625.69

Purity: 98%

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Density: 1.33±0.1 g/cm3

Boiling Point: 754.6±70.0 °C at 760 mmHg

InChIKey: NOJIJRBENLXFTN-AVURGOBBSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N=CN(C)C)CO)OP(=O)(OCCC#N)OCC=C

IUPAC Name: [(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[2-(dimethylaminomethylideneamino)-6-oxo-1H-purin-9-yl]-2-(hydroxymethyl)oxolan-3-yl] 2-cyanoethyl prop-2-enyl phosphate

InChI: InChI=1S/C25H40N7O8PSi/c1-9-12-36-41(35,37-13-10-11-26)39-19-17(14-33)38-23(20(19)40-42(7,8)25(2,3)4)32-16-27-18-21(32)29-24(30-22(18)34)28-15-31(5)6/h9,15-17,19-20,23,33H,1,10,12-14H2,2-8H3,(H,29,30,34)/t17-,19-,20-,23-,41?/m1/s1

Synonyms: Allyl ((2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(2-(((dimethylamino)methylene)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl) (2-cyanoethyl) phosphate; 3'-Guanylic acid, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(dimethylamino)methylene]-, 2-cyanoethyl 2-propen-1-yl ester; 3'-Guanylic acid, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(dimethylamino)methylene]-, 2-cyanoethyl 2-propenyl ester

Cyclic GMP sodium salt

Description: Cyclic GMP or cGMP is a second messenger and it is biosynthesized from GTP by guanylate cyclases. Nitric oxide and natriuretic peptides arw activators of guanylate cyclases. cGMP activates protein kinase G (PKG) and modulates ion channel conductance, with signaling affecting diverse processes including smooth muscle relaxation and proliferation, phototransduction, and energy homeostasis.

CAT: BRP-01954

CAS: 40732-48-7

MF: C10H11N5NaO7P

MF: 367.19

Purity: 98%

Appearance: Crystalline Solid

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Storage: Store at 2-8 °C, protect from light

Melting Point: >240 °C

InChIKey: KMPIYXNEROUNOG-GWTDSMLYSA-M

CanonicalSMILES: C1C2C(C(C(O2)N3C=NC4=C3N=C(NC4=O)N)O)OP(=O)(O1)[O-].[Na+]

IUPAC Name: sodium;9-[(4aR,6R,7R,7aS)-7-hydroxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-1H-purin-6-one

InChI: InChI=1S/C10H12N5O7P.Na/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

Synonyms: cGMP sodium salt; Cyclic guanosine monophosphate sodium salt; Guanosine 3'5'-cyclic monophosphate sodium salt; Monosodium-GMP; Guanosine, cyclic 3',5'-(hydrogen phosphate), sodium salt (1:1); Guanosine, cyclic 3',5'-(hydrogen phosphate), monosodium salt; Cyclic 3',5'-guanosine monophosphate monosodium salt; Guanosine monophosphate monosodium salt; 3',5'-Cyclic GMP monosodium salt

Related CAS: 7665-99-8 (free acid)

2'-Deoxy-2'-fluoroadenosine-5'-triphosphate trilithium salt

Description: 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate lithium salt, a vital component employed in the field of biomedicine, exhibits remarkable attributes that contribute to its significance in academic and scientific pursuits. Particularly, it serves as a valuable resource for the advancement of antiviral therapeutics, focusing on the targeted treatment of widespread viral ailments including HIV and hepatitis. Operating as an adenosine triphosphate (ATP) analog, this compound showcases unparalleled capabilities in impeding viral replication and enhancing immune response.

CAT: BRP-01986

MF: C10H12FLi3N5O12P3

MF: 526.97

Purity: 95%

Appearance: Clear colorless liquid

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Storage: Store at -20 °C

InChIKey: VWPBTGUPEYHZTB-PUOVIKMVSA-K

CanonicalSMILES: [Li+].[Li+].[Li+].C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)F)N

IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H15FN5O12P3.3Li/c11-5-7(17)4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(5)16-3-15-6-8(12)13-2-14-9(6)16;;;/h2-5,7,10,17H,1H2,(H,21,22)(H,23,24)(H2,12,13,14)(H2,18,19,20);;;/q;3*+1/p-3/t4-,5-,7-,10-;;;/m1.../s1

Synonyms: 2'-F-dATP lithium salt; 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate lithium salt; 2'-F-dATP.3Li; 2'-Deoxy-2'-fluoroadenosine 5'-(tetrahydrogen triphosphate) lithium salt (1:3); 2'-Fluoro ATP lithium salt; 2'-Fluoro-2'-deoxy-ATP lithium salt; 2'-Fluoro-2'-deoxyadenosine-5'-triphosphate lithium salt; Lithium ((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate

Related CAS: 73449-07-7 (free acid)

2'-Deoxy-2'-fluoroadenosine 5'-Triphosphate

Description: 2'-Deoxy-2'-fluoroadenosine 5'-Triphosphate: A highly significant and invaluable modified nucleotide employed extensively in the fields of biochemistry and molecular biology for groundbreaking research purposes. Renowned for its pivotal role in the exploration of DNA replication, transcription, and translation mechanisms, this extraordinary compound serves as an indispensable tool. Its application spans across multifaceted investigations pertaining to drug resistance mechanisms, mutagenesis, and groundbreaking advancements in cancer research.

CAT: BRP-01987

CAS: 73449-07-7

MF: C10H15FN5O12P3

MF: 509.17

Purity: ≥95% by HPLC

Appearance: White to Off-white Powder

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Storage: Store at -20 °C

Density: 2.6±0.1 g/cm3

Boiling Point: 914.2±75.0°C at 760 mmHg

InChIKey: CCXCDDWASROAJA-QYYRPYCUSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)F)N

IUPAC Name: [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H15FN5O12P3/c11-5-7(17)4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(5)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17H,1H2,(H,21,22)(H,23,24)(H2,12,13,14)(H2,18,19,20)/t4-,5-,7-,10-/m1/s1

Synonyms: (((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid; Adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2'-fluoro-; 2'-Fluoro-2'-deoxyadenosine-5'-triphosphate; 2'-Deoxy-2'-fluoroadenosine 5'-(tetrahydrogen triphosphate); 2'-FdATP; 2'-Fluoro ATP; 2'-Fluoro-2'-deoxy-ATP; 2'-F-dATP2'-F-dATP

2'-Deoxy-2'-fluorocytidine-5'-triphosphate trilithium salt

Description: 2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is an indispensable compound in the field of biomedicine, finding extensive application in the research and development of antiviral agents to combat problematic viral infections such as HIV and hepatitis C. Offering exceptional efficacy, this product acts as a highly proficient substrate for DNA polymerases, thereby impeding viral replication through the disruption of nucleotide integration into the viral DNA structure.

CAT: BRP-01988

MF: C9H12FLi3N3O13P3

MF: 502.94

Purity: 95%

Appearance: Clear colorless liquid

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Storage: Store at -20 °C

InChIKey: UTGJQMZHRLJVTR-LLWADOMFSA-K

CanonicalSMILES: [Li+].[Li+].[Li+].C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)F

IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C9H15FN3O13P3.3Li/c10-6-7(14)4(24-8(6)13-2-1-5(11)12-9(13)15)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,14H,3H2,(H,19,20)(H,21,22)(H2,11,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1

Synonyms: 2'-F-dCTP lithium salt; 2'-Fluoro-2'-deoxycytidine-5'-triphosphate, lithium salt; 2'-F-dCTP trilithium salt; Lithium ((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 2'-Deoxy-2'-fluorocytidine 5'-(tetrahydrogen triphosphate) trilithium salt; 2'-Deoxy-2'-fluorocytidine triphosphate trilithium salt; 2'-Fluoro CTP trilithium salt; 2'-Fluoro-2'-deoxy-CTP trilithium salt; 2'-Fluoro-dCTP trilithium salt

Related CAS: 66840-03-7 (free acid)

2'-Fluoro-dCTP

Description: 2'-Fluoro-dCTP is a deoxycytosine analog that is incorporated in both DNA and RNA constructs to improve stability in vivo.

CAT: BRP-01989

CAS: 66840-03-7

MF: C9H15FN3O13P3

MF: 485.15

Purity: ≥95% by HPLC

Appearance: White to off-white powder or colorless liquid

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Storage: Store at -20 °C

Density: 2.44±0.1 g/cm3 (Predicted)

Boiling Point: 812.9±75.0 °C at 760 mmHg

InChIKey: YKEIUAOIVAXJRI-XVFCMESISA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)F

IUPAC Name: [[(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H15FN3O13P3/c10-6-7(14)4(24-8(6)13-2-1-5(11)12-9(13)15)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,14H,3H2,(H,19,20)(H,21,22)(H2,11,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

Synonyms: 2'-Fluoro-2'-deoxycytidine-5'-triphosphate; 2'-Deoxy-2'-fluorocytidine 5'-O-triphosphate; 2'-Deoxy-2'-fluorocytidine 5'-(tetrahydrogen triphosphate); Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2'-fluoro-; [[(2R,3R,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-4-fluoro-3-hydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate; 2'-Deoxy-2'-fluorocytidine triphosphate; 2'-Fluoro CTP; 2'-F-dCTP; 2'-Fluoro-2'-deoxy-CTP; 2'-Fluoro-2'-deoxycytidine triphosphate; 2'-Fluoro-dCTP; 2'-fluorodeoxy-CTP

2'-Deoxy-2'-fluoroguanosine 5'-triphosphate trilithium salt

Description: 2'-Deoxy-2'-fluoroguanosine 5'-Triphosphate is a crucial component in current biomedical research, utilized for the study of DNA synthesis and polymerase chain reactions (PCR). This modified nucleoside triphosphate acting as an effective substrate analog for DNA polymerases and assists in investigating nucleic acid structures and functions. It is extensively utilized in drug discovery studies targeting viral infections, such as HIV and hepatitis C, aiding in the development of potential antiviral therapies.

CAT: BRP-01990

MF: C10H12FLi3N5O13P3

MF: 542.97

Purity: ≥95%

Appearance: white to off-white powder

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Storage: Store at -20 °C

InChIKey: LJROCXPLGCSGGF-MPTIMWNFSA-K

CanonicalSMILES: [Li+].[Li+].[Li+].C1=NC2=C(N1C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)F)N=C(NC2=O)N

IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H15FN5O13P3.3Li/c11-4-6(17)3(1-26-31(22,23)29-32(24,25)28-30(19,20)21)27-9(4)16-2-13-5-7(16)14-10(12)15-8(5)18;;;/h2-4,6,9,17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,12,14,15,18);;;/q;3*+1/p-3/t3-,4-,6-,9-;;;/m1.../s1

Synonyms: 2'-F-dGTP lithium salt; 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate lithium salt; 2'-F-dGTP trilithium salt; Lithium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 2'-F-dGTP trilithium salt; 2'-Deoxy-2'-fluoroguanosine 5'-(tetrahydrogen triphosphate) trilithium salt; 2'-Fluoro GTP trilithium salt; 2'-Fluoro-2'-deoxy-GTP trilithium salt; 2'-Fluoro-2'-deoxyguanosine-5'-triphosphate lithium salt

Related CAS: 202186-97-8 (free acid)

2'-Deoxy-2'-fluoroguanosine-5'-triphosphate

Description: 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate is an important reagent widely used in nucleic acid research and diagnosis in biomedical industry. Its significance lies in the fact that it is an essential component of synthetic modified DNA strands, and its role is enhanced by the excellent stability conferred by its unique fluorine substitution and nuclease resistance. Multiple applications of the compound include drug discovery, genetic engineering, and research related to antiviral drugs.

CAT: BRP-01991

CAS: 202186-97-8

MF: C10H15FN5O13P3

MF: 525.17

Purity: 95%

Appearance: White to off-white powder or colorless liquid

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Storage: Store at -20 °C

Density: 2.68±0.1 g/cm3

InChIKey: KYEUAYQSPABKRL-DXTOWSMRSA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)F)N=C(NC2=O)N

IUPAC Name: [[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H15FN5O13P3/c11-4-6(17)3(1-26-31(22,23)29-32(24,25)28-30(19,20)21)27-9(4)16-2-13-5-7(16)14-10(12)15-8(5)18/h2-4,6,9,17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,12,14,15,18)/t3-,4-,6-,9-/m1/s1

Synonyms: 2'-Deoxy-2'-fluoro-D-guanosine-5'-triphosphate; 2'-F-dGTP; 2'-Deoxy-2'-fluoroguanosine 5'-(tetrahydrogen triphosphate); 2'-Fluoro GTP; 2'-Fluoro-2'-deoxy-GTP; 2'-Fluoro-2'-deoxyguanosine-5'-triphosphate; 2'-FdGTP; 2'-deoxy-2'-fluoroguanosine triphosphate; 2'-Fluoro-2'-deoxyguanosine 5'-triphosphoric acid; Guanosine, 2'-deoxy-2'-fluoro-, 5'-(tetrahydrogen triphosphate); 2'F-dGTP; 2'-Fluoro-dGTP

Related CAS: 170784-61-9 (triammonium salt) ; 170784-60-8 (diammonium salt)