Nucleotides

UTPγS trisodium salt

Description: UTPγS trisodium salt is a selective P2Y2 and P2Y4 receptor agonist.

CAT: BRP-01652

CAS: 1266569-94-1

Molecular Formula: C9H12N2Na3O14P3S

Molecular Weight: 566.15

Purity: ≥95% by HPLC

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InChIKey: DBXMFBSCFRDIOA-LLWADOMFSA-K

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=S)(O)[O-])O)O.[Na+].[Na+].[Na+]

IUPAC Name: trisodium;[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [hydroxy(oxido)phosphinothioyl] phosphate

InChI: InChI=1S/C9H15N2O14P3S.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(23-8)3-22-26(16,17)24-27(18,19)25-28(20,21)29;;;/h1-2,4,6-8,13-14H,3H2,(H,16,17)(H,18,19)(H,10,12,15)(H2,20,21,29);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1

Synonyms: Trisodium ({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)({[hydroxy(oxido)sulfanylidene-|E-phosphanyl]oxy})phosphinate; Uridine-5'-(γ-thio)-triphosphate trisodium salt; UTP-γS trisodium salt; Uridine 5'-O-(3-thiotriphosphate) trisodium salt

Related CAS: 79049-97-1 (free acid)

2'-O-Methylguanosine-5'-triphosphate trilithium salt

Description: 2'-O-Methylguanosine-5'-triphosphate trilithium salt, a highly versatile compound, can be employed as an efficient probe for investigating RNA metabolism. It possesses the remarkable capability of obstructing RNA chain elongation, thus making it an invaluable research tool in the field. In addition to its chain terminating property, it also exhibits remarkable affinity with RNA-binding proteins and catalytic ribozymes, rendering it ideal for studying complex RNA-protein interactions and enzymatic activities.

CAT: BRP-01653

Molecular Formula: C11H15Li3N5O14P3

Molecular Weight: 555.00

Purity: ≥97% by HPLC

Appearance: Clear colorless liquid

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InChIKey: DNABKBYLELJGQR-MSQVLRTGSA-K

CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O

IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C11H18N5O14P3.3Li/c1-26-7-6(17)4(2-27-32(22,23)30-33(24,25)29-31(19,20)21)28-10(7)16-3-13-5-8(16)14-11(12)15-9(5)18;;;/h3-4,6-7,10,17H,2H2,1H3,(H,22,23)(H,24,25)(H2,19,20,21)(H3,12,14,15,18);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1

Synonyms: 2'-O-Me-GTP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate

Related CAS: 61556-44-3 (free acid)

2'-O-Methyladenosine-5'-triphosphate trilithium salt

Description: 2'-O-Methyladenosine-5'-triphosphate trilithium salt, a prominent nucleotide analog in enzymatic assays detecting ATP-utilizing proteins, and in RNA structure/function studies, specific to RNA modification and translation analysis, showcases its multifarious and intriguing features. Its utilization in diverse experimental applications underlines its enormous potential and capacity to facilitate cutting-edge researches in biomedical and pharmaceutical sciences.

CAT: BRP-01654

Molecular Formula: C11H15Li3N5O13P3

Molecular Weight: 539.00

Purity: ≥97% by HPLC

Appearance: Clear colorless liquid

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InChIKey: QIQIMTPLFXIYPZ-MTQUBGKESA-K

CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=NC3=C(N=CN=C32)N)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O

IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C11H18N5O13P3.3Li/c1-25-8-7(17)5(2-26-31(21,22)29-32(23,24)28-30(18,19)20)27-11(8)16-4-15-6-9(12)13-3-14-10(6)16;;;/h3-5,7-8,11,17H,2H2,1H3,(H,21,22)(H,23,24)(H2,12,13,14)(H2,18,19,20);;;/q;3*+1/p-3/t5-,7-,8-,11-;;;/m1.../s1

Synonyms: 2'-O-methyl-adenosine-5'-triphosphate, lithium salt; 2'-O-Me-ATP Lithium Salt; lithium ((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 2'-O-Me-ATP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methyladenosine; Adenosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3)

Related CAS: 30948-06-2 (free acid) ; 100020-58-4 (tetrasodium salt)

2'-O-Methylcytidine-5'-triphosphate trilithium salt

Description: 2'-O-Methylcytidine-5'-triphosphate trilithium salt, a nucleotide derivative employed frequently in RNA biosynthesis and modification investigations, holds immense promise in cancer therapies, especially as a competitive inhibitor of RNA polymerase II elongation. Compelling evidence also demonstrates its success as an inhibitor of viral replication, particularly in the context of hepatitis C.

CAT: BRP-01655

Molecular Formula: C10H15Li3N3O14P3

Molecular Weight: 514.98

Purity: ≥97% by HPLC

Appearance: Clear colorless liquid

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InChIKey: RIFSDAPMKYBRDH-WKMNQBAXSA-K

CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=CC(=NC2=O)N)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O

IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H18N3O14P3.3Li/c1-23-8-7(14)5(25-9(8)13-3-2-6(11)12-10(13)15)4-24-29(19,20)27-30(21,22)26-28(16,17)18;;;/h2-3,5,7-9,14H,4H2,1H3,(H,19,20)(H,21,22)(H2,11,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t5-,7-,8-,9-;;;/m1.../s1

Synonyms: 2'-O-methyl-cytidine-5'-triphosphate, lithium salt; 2'-O-Me-CTP Lithium Salt; 2'-O-Me-CTP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methylcytidine; Cytidine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 2'-O-methyl-Cytidine-5'-triphosphate, trilithium salt

Related CAS: 143028-98-2 (free acid)

2'-O-Methyluridine-5'-triphosphate trilithium salt

Description: 2'-O-Methyluridine-5'-triphosphate trilithium salt, a biochemical reagent widely applied in biomedicine to investigate RNA transcription and modification, is a valuable research tool with incomparable properties that afford an accurate insight of cellular processes related to RNA function and modification. Scientists favor its use as a substrate for RNA polymerase, that enables them to scrutinize RNA synthesis and modification of transcripts. Furthermore, this trilithium salt is constructive in analyzing RNA-protein interactions and probing ribozymes.

CAT: BRP-01656

Molecular Formula: C10H14Li3N2O15P3

Molecular Weight: 515.96

Purity: ≥97% by HPLC

Appearance: Clear colorless liquid

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InChIKey: ZBEHXEVNNHLIAB-WKMNQBAXSA-K

CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=CC(=O)NC2=O)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O

IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H17N2O15P3.3Li/c1-23-8-7(14)5(25-9(8)12-3-2-6(13)11-10(12)15)4-24-29(19,20)27-30(21,22)26-28(16,17)18;;;/h2-3,5,7-9,14H,4H2,1H3,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18);;;/q;3*+1/p-3/t5-,7-,8-,9-;;;/m1.../s1

Synonyms: 2'-O-Methyl-uridine-5'-triphosphate, lithium salt; 2'-O-Me-UTP Lithium Salt; lithium ((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 2'-OMe-UTP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methyluridine; Uridine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); 2'-methoxy-UTP trilithium salt; 2'-O-methyl-Uridine-5'-triphosphate, trilithium salt; 2'-OMe-UTP.Li3

Related CAS: 143028-99-3 (free acid)

8-Bromoadenosine 5'-Triphosphate Sodium Salt

Description: 8-Bromoadenosine 5'-Triphosphate Sodium Salt is a reagent required for the characterization (stoichiometry, geometry, and stability constant) of ATP:Fe(II) complex.

CAT: BRP-01659

CAS: 81035-56-5

Molecular Formula: C10H15BrN5O13P3 (free acid)

Molecular Weight: 586.08 (free acid)

Purity: ≥95% by HPLC

Appearance: Clear colorless to yellow liquid

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InChIKey: CDLMOHDSMLZBCO-GWTDSMLYSA-M

CanonicalSMILES: C1=NC(=C2C(=N1)N(C(=N2)Br)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)[O-])O)O)N.[Na+]

IUPAC Name: sodium;[[[(2R,3S,4R,5R)-5-(6-amino-8-bromopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H15BrN5O13P3.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(18)5(17)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;/h2-3,5-6,9,17-18H,1H2,(H,22,23)(H,24,25)(H2,12,13,14)(H2,19,20,21);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

Synonyms: 8-bromo-adenosine-5'-triphosphate, sodium salt; 8-Br-ATP, Sodium Salt; 8-Bromo-adenosine 5'-(Tetrahydrogen triphosphate) Sodium Salt; Adenosine 5'-(tetrahydrogen triphosphate), 8-bromo-, sodium salt; 8-Bromo-ATP sodium salt

Related CAS: 23567-97-7 (free acid) ; 35892-96-7 (tetrasodium salt)

8-Bromo-ATP

Description: 8-Bromo-ATP is a potent analog of adenosine triphosphate (ATP), a crucial energy carrier in cells. Widely used in biomedicine, 8-Bromo-ATP exhibits high affinity towards purinergic receptors and is often employed to study their function and signaling pathways. Additionally, this compound serves as a substrate for various enzymatic reactions, enabling researchers to investigate ATP-dependent processes in drug discovery and disease mechanisms.

CAT: BRP-01660

CAS: 23567-97-7

Molecular Formula: C10H15BrN5O13P3

Molecular Weight: 586.08

Purity: ≥95% by HPLC

Appearance: clear aqueous solution

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Density: 2.85±0.1 g/cm3

Boiling Point: 983.1±75.0 °C at 760 mmHg

InChIKey: VPAHIVDZXBLTTM-UUOKFMHZSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C(=N2)Br)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

IUPAC Name: [[(2R,3S,4R,5R)-5-(6-amino-8-bromopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H15BrN5O13P3/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(18)5(17)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,17-18H,1H2,(H,22,23)(H,24,25)(H2,12,13,14)(H2,19,20,21)/t3-,5-,6-,9-/m1/s1

Synonyms: 8-Bromoadenosine 5'-Triphosphate; (8Br-ATP); 8-Br-ATP; 8-Bromoadenosine 5'-(tetrahydrogen triphosphate); Adenosine, 8-bromo-, 5'-(tetrahydrogen triphosphate); 8-Bromo ATP; 8-Bromoadenosine triphosphate; ((2R,3S,4R,5R)-5-(6-Amino-8-bromo-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate

Related CAS: 81035-56-5 (x-sodium salt) ; 35892-96-7 (tetrasodium salt)

8-Bromo-GTP

Description: 8-Bromo-GTP is a GTP analog that can inhibit GTP-hydrolase. It competitively inhibits GTPase (IC50 = 32 μM) and competes with ATP for the binding center of RNA-polymerase.

CAT: BRP-01661

CAS: 23197-98-0

Molecular Formula: C10H15BrN5O14P3

Molecular Weight: 602.08

Purity: ≥95% by HPLC

Appearance: clear aqueous solution

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InChIKey: CNYUHYBBHQMZQJ-UMMCILCDSA-N

CanonicalSMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2Br)O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-8-bromo-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H15BrN5O14P3/c11-9-13-3-6(14-10(12)15-7(3)19)16(9)8-5(18)4(17)2(28-8)1-27-32(23,24)30-33(25,26)29-31(20,21)22/h2,4-5,8,17-18H,1H2,(H,23,24)(H,25,26)(H2,20,21,22)(H3,12,14,15,19)/t2-,4-,5-,8-/m1/s1

Synonyms: (8Br-GTP); 8-Bromo-guanosine-5'-triphosphate; 8-Bromoguanosine 5'-triphosphate; 8-Bromoguanosine triphosphate

Guanylyl-(3',5')-adenosine

Description: Guanylyl-(3',5')-adenosine, a cyclic nucleotide second messenger, intricately orchestrates various cellular signaling pathways, rendering it crucial in regulating a myriad of physiological functions, ranging from neurotransmitter release to smooth muscle contraction. A versatile molecule of interest, this compound boasts promising potential in the therapeutic arena, especially for treating cardiovascular diseases, such as hypertension and heart failure, thanks to its adeptness in modulating platelet activation and gene expression.

CAT: BRP-01662

CAS: 6554-00-3

Molecular Formula: C20H25N10O11P

Molecular Weight: 612.45

Purity: ≥95% by AX-HPLC

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Storage: Store at -20°C

Density: 2.4±0.1 g/cm3

Boiling Point: 1147.4±75.0 °C at 760 mmHg

InChIKey: PBWYGOYNGCCLAU-INFSMZHSSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OC4C(OC(C4O)N5C=NC6=C5N=C(NC6=O)N)CO)O)O)N

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

InChI: InChI=1S/C20H25N10O11P/c21-14-8-15(24-3-23-14)29(4-25-8)18-11(33)10(32)7(40-18)2-38-42(36,37)41-13-6(1-31)39-19(12(13)34)30-5-26-9-16(30)27-20(22)28-17(9)35/h3-7,10-13,18-19,31-34H,1-2H2,(H,36,37)(H2,21,23,24)(H3,22,27,28,35)/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1

Synonyms: GmpA; Guanine ribonucleotidyl-(3'-5')-adenosine; Adenylyl-(5',3')-guanosine; GpA RNA Dinucleotide (5'-3'); GpA; Guanylyladenosine

Related CAS: 103213-26-9 (monoammonium salt) ; 21052-30-2 (x-ammonium salt) ; 103192-56-9 (monosodium salt)

Adenylyl-(3'-5')-cytidine

Description: Adenylyl-(3'-5')-cytidine is a nucleotide derivative involved in RNA metabolism and signaling pathways. It plays a role in various biological processes, including RNA modification and cellular signaling. Adenylyl-(3'-5')-cytidine is used in biochemical and molecular biology research to study RNA-related processes, including RNA capping mechanisms, mRNA processing, and interactions with enzymes involved in RNA metabolism. This compound serves as a model substrate to investigate RNA modification dynamics and its impact on RNA stability and function.

CAT: BRP-01663

CAS: 4833-63-0

Molecular Formula: C19H25N8O11P

Molecular Weight: 572.42

Purity: 95%

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Storage: Store at -20 °C

Density: 2.23±0.1 g/cm3

Boiling Point: 993.2±75.0 °C at 760 mmHg

InChIKey: NHEPQPHJXSVOGF-KPKSGTNCSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=NC5=C(N=CN=C54)N)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C19H25N8O11P/c20-9-1-2-26(19(32)25-9)17-12(30)11(29)8(37-17)4-35-39(33,34)38-14-7(3-28)36-18(13(14)31)27-6-24-10-15(21)22-5-23-16(10)27/h1-2,5-8,11-14,17-18,28-31H,3-4H2,(H,33,34)(H2,20,25,32)(H2,21,22,23)/t7-,8-,11-,12-,13-,14-,17-,18-/m1/s1

Synonyms: Cytidylyl(5'->3')adenosine; AmpC; 3'-Adenylic acid, 5'-ester with cytidine; Adenosine, cytidylyl-(5'→3')-; Adenylyl-(3'→5')-cytidine; Adenylylcytosine; ApC; NSC 131652; NSC 91551

Related CAS: 27553-02-2 (monoammonium salt) ; 63660-18-4 (x-ammonium salt) ; 25763-55-7 (monosodium salt)

Cytidylyl-(3'-5')-guanosine

Description: Cytidylyl-(3'-5')-guanosine is a pivotal compound entity, assuming a pivotal role in the intricacies of RNA synthesand serves as a potent catalyst for RNA-dependent protein kinase.

CAT: BRP-01664

CAS: 2382-65-2

Molecular Formula: C19H25N8O12P

Molecular Weight: 588.42

Purity: 95%

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Storage: Store at -20 °C

Density: 2.31±0.1 g/cm3

Boiling Point: 1057.6 °C at 760 mmHg

InChIKey: CTMZLDSMFCVUNX-VMIOUTBZSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C4NC(=NC5=O)N)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C19H25N8O12P/c20-8-1-2-26(19(33)23-8)17-12(31)13(6(3-28)37-17)39-40(34,35)36-4-7-10(29)11(30)16(38-7)27-5-22-9-14(27)24-18(21)25-15(9)32/h1-2,5-7,10-13,16-17,28-31H,3-4H2,(H,34,35)(H2,20,23,33)(H3,21,24,25,32)/t6-,7-,10-,11-,12-,13-,16-,17-/m1/s1

Synonyms: CmpG; Cytidylyl-3'-5'-guanosine; CpG RNA Dinucleotide (5'-3'); Cytidylyl-(3'→5')-guanosine; (3'-5')CpG; Cytidine, guanylyl-(5'→3')-; Cytidylylguanosine; Guanosine cytidine 3',5'-monophosphate; CpG

Related CAS: 27553-01-1 (monoammonia salt) ; 21052-28-8 (x-ammonium salt) ; 172793-57-6 (monosodium salt) ; 172793-58-7 (monopotassium salt)

Adenylyl-(3'-5')-adenosine

Description: Adenylyl-(3'-5')-adenosine is a pivotal biomolecule with extensive applications in studying signaling pathways, particularly cAMP-dependent processes. It aids in understanding cyclic nucleotide metabolism and exploring associated afflictions encompassing cancer, diabetes and cardiovascular disorders.

CAT: BRP-01665

CAS: 2391-46-0

Molecular Formula: C20H25N10O10P

Molecular Weight: 596.45

Purity: ≥98%

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Storage: Store at -20 °C

Density: 2.3±0.1 g/cm3

Boiling Point: 1081.3±75.0 °C at 760 mmHg

InChIKey: UYSXBCQACJTYFS-XPWFQUROSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OC4C(OC(C4O)N5C=NC6=C(N=CN=C65)N)CO)O)O)N

IUPAC Name: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C20H25N10O10P/c21-15-9-17(25-3-23-15)29(5-27-9)19-12(33)11(32)8(39-19)2-37-41(35,36)40-14-7(1-31)38-20(13(14)34)30-6-28-10-16(22)24-4-26-18(10)30/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H2,21,23,25)(H2,22,24,26)/t7-,8-,11-,12-,13-,14-,19-,20-/m1/s1

Synonyms: ApA RNA Dinucleotide (5'-3'); AmpA; 5'-Adenylic acid, 3'-ester with adenosine; 3',5'-ApA; D-Adenylyl-(3'-5')-D-adenosine; Adenylyl-(5'→3')-adenosine; Adenylyladenosine; Diadenosine 3',5'-monophosphate; NSC 91555; ApA

Related CAS: 102029-96-9 (monoammonia salt) ; 21027-46-3 (x-ammonium salt) ; 61240-16-2 (monosodium salt)

Guanylyl-(3'-5')-cytidine

Description: Guanylyl-3',5'-cytidine, a biochemical compound, is a valuable tool in the biomedical industry for delving deep into the intricacies of RNA capping mechanisms. It mimics guanosine 5’-triphosphate (GTP), a naturally occurring molecule, and is utilized to investigate the cellular processes of various RNA viruses, including hepatitis C virus (HCV). Furthermore, guanylyl-3',5'-cytidine holds the promise of therapeutic benefits for HCV and other RNA viral infections.

CAT: BRP-01666

CAS: 4785-04-0

Molecular Formula: C19H25N8O12P

Molecular Weight: 588.42

Purity: 95%

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Storage: Store at -20 °C

Density: 2.31±0.1 g/cm3

Boiling Point: 1057.6 °C at 760 mmHg

InChIKey: DQTQQHQGSZWEMR-VMIOUTBZSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=NC5=C4NC(=NC5=O)N)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

InChI: InChI=1S/C19H25N8O12P/c20-8-1-2-26(19(33)23-8)16-11(30)10(29)7(38-16)4-36-40(34,35)39-13-6(3-28)37-17(12(13)31)27-5-22-9-14(27)24-18(21)25-15(9)32/h1-2,5-7,10-13,16-17,28-31H,3-4H2,(H,34,35)(H2,20,23,33)(H3,21,24,25,32)/t6-,7-,10-,11-,12-,13-,16-,17-/m1/s1

Synonyms: Guanylyl-3',5'-cytidine; Guanylyl-(3',5')-cytidine; GpC RNA Dinucleotide (5'-3'); Cytidylyl-(5'->3')-guanosine; 3'-Guanylic acid, 5'-ester with cytidine; Guanosine, cytidylyl-(5'→3')-; Guanylyl-(3'→5')-cytidine; GC; GpC

Related CAS: 98046-67-4 (monoammonia salt) ; 84825-35-4 (monoammonia salt octahydrate) ; 98046-66-3 (monosodium salt) ; 55015-32-2 (calcium salt (2:1)) ; 172793-59-8 (monopotassium salt)

Uridylyl-(3'-5')-cytidine

Description: Uridylyl-(3'-5')-cytidine, a pivotal enzyme central to the biomedicine sector, exhibits invaluable utility for combatting select viral infections and malignancies. Its significance lies in RNA synthesis, bolstering cellular functionality and resilience.

CAT: BRP-01667

CAS: 3013-97-6

Molecular Formula: C18H24N5O13P

Molecular Weight: 549.40

Purity: ≥95% by AX-HPLC

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Storage: Store at -20 °C

Density: 2.13±0.1 g/cm3

InChIKey: LENQVXALZPDAFB-NCOIDOBVSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=CC(=O)NC4=O)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C18H24N5O13P/c19-9-1-3-22(17(29)20-9)15-12(27)11(26)8(35-15)6-33-37(31,32)36-14-7(5-24)34-16(13(14)28)23-4-2-10(25)21-18(23)30/h1-4,7-8,11-16,24,26-28H,5-6H2,(H,31,32)(H2,19,20,29)(H,21,25,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1

Synonyms: UpC RNA Dinucleotide (5'-3'); Cytidylyl-(5',3')-uridine; 3'-Uridylic acid, 5'-ester with cytidine; Uridine, cytidylyl-(5'→3')-; Uridylyl-(3'→5')-cytidine; Cytidylyl-(5'→3')-uridine; NSC 131649

Related CAS: 27531-20-0 (monoammonia salt) ; 108347-78-0 (x-ammonium salt) ; 30796-28-2 (polymers)

Guanylyl-(3'-5')-guanosine

Description: Guanylyl-(3'-5')-guanosine is a highly significant compound extensively employed in biomedical research, emerging as an indispensable player in signal transduction. Its pivotal role lies in its capacity to function as a second messenger molecule, especially in the modulation of cyclic GMP levels. Diverse cellular phenomena, encompassing vasodilation, neurotransmission and immune responses is are meticulously investigated utilizing this molecule to scrutinize the cGMP-dependent pathways.

CAT: BRP-01668

CAS: 3353-33-1

Molecular Formula: C20H25N10O12P

Molecular Weight: 628.45

Purity: ≥95% by AX-HPLC

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Storage: Store at -20 °C

Density: 2.5±0.1 g/cm3

Boiling Point: 1215.2±75.0 °C at 760 mmHg

InChIKey: MNXLMHSUERRXOE-MHARETSRSA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OC4C(OC(C4O)N5C=NC6=C5N=C(NC6=O)N)CO)O)O)N=C(NC2=O)N

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C20H25N10O12P/c21-19-25-13-7(15(35)27-19)23-3-29(13)17-10(33)9(32)6(41-17)2-39-43(37,38)42-12-5(1-31)40-18(11(12)34)30-4-24-8-14(30)26-20(22)28-16(8)36/h3-6,9-12,17-18,31-34H,1-2H2,(H,37,38)(H3,21,25,27,35)(H3,22,26,28,36)/t5-,6-,9-,10-,11-,12-,17-,18-/m1/s1

Synonyms: GpG RNA Dinucleotide (5'-3'); 3'-Guanylic acid, 3',5'-ester with guanosine; Guanylyl-(3'→5')-guanosine; GmpG; GpG; Guanosyl(3',5')guanosine

Related CAS: 97403-87-7 (monoammonia salt) ; 21052-31-3 (x-ammonium salt) ; 137629-38-0 (TEA salt) ; 49717-61-5 (homopolymer) ; 146819-37-6 (x-sodium salt) ; 146819-38-7 (x-potassium salt) ; 146819-36-5 (x-lithium salt)

Cytidylyl-(3'-5')-cytidine

Description: Cytidylyl-(3'-5')-cytidine is a biochemical utilized in the production of RNA. It also plays a crucial role in signaling pathways. In the biomedical field, it is being researched as a potential treatment for certain cancers, such as pancreatic cancer.

CAT: BRP-01669

CAS: 2536-99-4

Molecular Formula: C18H25N6O12P

Molecular Weight: 548.40

Purity: ≥95% by AX-HPLC

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Storage: Store at -20°C

Density: 2.13±0.1 g/cm3

Boiling Point: 905.8±75.0 °C at 760 mmHg

InChIKey: PTLMIIUMLITBQT-NCOIDOBVSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=CC(=NC4=O)N)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C18H25N6O12P/c19-9-1-3-23(17(29)21-9)15-12(27)11(26)8(35-15)6-33-37(31,32)36-14-7(5-25)34-16(13(14)28)24-4-2-10(20)22-18(24)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H2,19,21,29)(H2,20,22,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1

Synonyms: CpC RNA Dinucleotide (5'-3'); CmpC; 3'-Cytidylic acid, 5'-ester with cytidine; Cytidylyl-(3'→5')-cytidine; CpC; NSC 131650; NSC 91550

Related CAS: 27552-98-3 (monoammonia salt)

Guanylyl-(3'-5')-uridine

Description: Guanylyl-(3'-5')-uridine is a dinucleotide derivative that participates in RNA capping processes. It is involved in the addition of a guanosine cap to the 5' end of RNA molecules during RNA processing, essential for mRNA stability and translation initiation. It is utilized in biochemical and molecular biology research to investigate RNA-related processes, including RNA capping mechanisms, mRNA processing, and interactions with RNA-binding proteins. This compound serves as a valuable tool in elucidating the roles of modified nucleotides in RNA biology and in studying enzymatic reactions involving RNA molecules.

CAT: BRP-01670

CAS: 4785-07-3

Molecular Formula: C19H24N7O13P

Molecular Weight: 589.41

Purity: ≥98%

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Storage: Store at -20 °C

Density: 2.31±0.1 g/cm3

InChIKey: HQXUOLIEBGPXRE-VMIOUTBZSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=NC5=C4N=C(NC5=O)N)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

InChI: InChI=1S/C19H24N7O13P/c20-18-23-14-9(15(32)24-18)21-5-26(14)17-12(31)13(6(3-27)37-17)39-40(34,35)36-4-7-10(29)11(30)16(38-7)25-2-1-8(28)22-19(25)33/h1-2,5-7,10-13,16-17,27,29-31H,3-4H2,(H,34,35)(H,22,28,33)(H3,20,23,24,32)/t6-,7-,10-,11-,12-,13-,16-,17-/m1/s1

Synonyms: GmpU; Guanylyl(3'-5')uridine; 3'-Guanylic acid, 5'-ester with uridine; Guanosine, uridylyl-(5'→3')-; Guanylyl-(3'→5')-uridine; GU; Guanosyl-(3',5')-uridine; Guanylyl-(3',5')-uridine; NSC 92173; GU dinucleotide

Related CAS: 41547-83-5 (monoammonia salt) ; 21052-32-4 (x-ammonium salt) ; 27531-23-3 (TEA salt)

Adenylyl-(3'-5')-guanosine

Description: ADENYLYL-(3'-5')-GUANOSINE, a fundamental molecule in cellular signaling pathways, is an indispensable regulator of intracellular communication. It assumes a pivotal position in the control of diverse biological phenomena encompassing DNA synthesis and repair, cell growth, as well as immune responses. In the realm of biomedicine, ADENYLYL-(3'-5')-GUANOSINE finds utility in the investigation of second messenger signaling, cyclic nucleotide regulation, and the therapeutic management of afflictions including cancer, cardiovascular disorders, and neurodegenerative conditions.

CAT: BRP-01671

CAS: 3352-23-6

Molecular Formula: C20H25N10O11P

Molecular Weight: 612.45

Purity: ≥95%

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Storage: Store at -20°C

Density: 2.41±0.1 g/cm3

Boiling Point: 1147.4±75.0 °C at 760 mmHg

InChIKey: LWBLDUTUVIXFJE-INFSMZHSSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C5N=C(NC6=O)N)O)O)O)N

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C20H25N10O11P/c21-14-8-15(24-3-23-14)29(4-25-8)19-12(34)13(6(1-31)39-19)41-42(36,37)38-2-7-10(32)11(33)18(40-7)30-5-26-9-16(30)27-20(22)28-17(9)35/h3-7,10-13,18-19,31-34H,1-2H2,(H,36,37)(H2,21,23,24)(H3,22,27,28,35)/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1

Synonyms: Guanosine, adenylyl-(3'→5')-; 3'-Adenylic acid, 5'-ester with guanosine; Adenylyl-(3'→5')-guanosine; A-G; Adenosine, guanylyl-(5'→3')-; NSC 91554; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl) hydrogen phosphate; 3'-O-(5'-Guanylyl)adenosine

Related CAS: 102029-53-8 (monoammonia salt) ; 21027-47-4 (x-ammonium salt) ; 30796-29-3 (polymers)

Adenylyl-3'-5'-cytidine

Description: Adenylyl-3'-5'-cytidine is a highly effective and specialized adenylyl cyclase activator, holding applications in biomedical research for investigating the cyclic adenosine monophosphate (cAMP) signaling pathways.

CAT: BRP-01672

CAS: 2382-66-3

Molecular Formula: C19H25N8O11P

Molecular Weight: 572.42

Purity: 98%

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Storage: Store at -20 °C

Density: 2.23±0.1 g/cm3

Melting Point: 173-175 °C

Boiling Point: 993.2±75.0 °C at 760 mmHg

Application: Enzyme Inhibitors

InChIKey: ZLVJWOGZEAIPAO-KPKSGTNCSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

InChI: InChI=1S/C19H25N8O11P/c20-9-1-2-26(19(32)25-9)18-13(31)14(7(3-28)36-18)38-39(33,34)35-4-8-11(29)12(30)17(37-8)27-6-24-10-15(21)22-5-23-16(10)27/h1-2,5-8,11-14,17-18,28-31H,3-4H2,(H,33,34)(H2,20,25,32)(H2,21,22,23)/t7-,8-,11-,12-,13-,14-,17-,18-/m1/s1

Synonyms: CmpA; Adenylyl-3'-5'-D-cytidine; 5'-Adenylic acid, 3'-ester with cytidine; Cytidylyl-(3'→5')-adenosine; Cytidine, adenylyl-(5'→3')-; Cytidylyl-3',5'-adenosine; NSC 91552; Cytidylyl adenosine; Cytidylyl-3',5'-adenosine phosphate; (3'-5')CpA; Cytidylyl-(3'-5')-adenosine; CpA; Cytidylyl(3',5')adenosine

Related CAS: 27553-00-0 (monoammonia salt) ; 21052-27-7 (x-ammonium salt) ; 25602-07-7 (monosodium salt) ; 63660-19-5 (x-sodium salt)

Uridylyl-(3'-5')-adenosine

Description: Uridylyl-(3'-5')-adenosine, an indispensable enzyme in the field of biomedicine, holds immense significance owing to its pivotal role in nucleotide metabolism. Its involvement in the synthesis of flavin adenine dinucleotide (FAD), a fundamental coenzyme for diverse enzymatic reactions, further amplifies its importance. Prominently employed for investigating FAD-dependent enzymes and their potential implications in a wide array of ailments like cancer, cardiovascular disorders, and neurodegenerative conditions, this product emerges as a scholarly tool in scientific exploration.

CAT: BRP-01673

CAS: 3256-24-4

Molecular Formula: C19H24N7O12P

Molecular Weight: 573.40

Purity: ≥95% by AX-HPLC

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Storage: Store at -20 °C

Density: 2.23±0.1 g/cm3

InChIKey: SWTWQWKNQDDGCS-KPKSGTNCSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C19H24N7O12P/c20-15-10-16(22-5-21-15)26(6-23-10)17-12(30)11(29)8(37-17)4-35-39(33,34)38-14-7(3-27)36-18(13(14)31)25-2-1-9(28)24-19(25)32/h1-2,5-8,11-14,17-18,27,29-31H,3-4H2,(H,33,34)(H2,20,21,22)(H,24,28,32)/t7-,8-,11-,12-,13-,14-,17-,18-/m1/s1

Synonyms: UpA RNA Dinucleotide (5'-3'); Uridylyladenosine; Uridine-3',5'-adenosine phosphate; (3',5')-Uridylyladenosine; 5'-Adenylic acid, ester with uridine-(5'→3'); Uridylyl-(3'→5')-adenosine; (3'-5')UpA; Adenosine 5',3'-phosphouridine; NSC 118092; UmpA; UpA

Related CAS: 27531-21-1 (monoammonia salt) ; 21052-33-5 (x-ammonium salt) ; 160509-67-1 (monosodium salt) ; 35523-12-7 (hemihydrate)

UTPγS trisodium salt

2'-O-Methylguanosine-5'-triphosphate trilithium salt

2'-O-Methyladenosine-5'-triphosphate trilithium salt

2'-O-Methylcytidine-5'-triphosphate trilithium salt

2'-O-Methyluridine-5'-triphosphate trilithium salt

8-Bromoadenosine 5'-Triphosphate Sodium Salt

8-Bromo-ATP

8-Bromo-GTP

Guanylyl-(3',5')-adenosine

Adenylyl-(3'-5')-cytidine

Cytidylyl-(3'-5')-guanosine

Adenylyl-(3'-5')-adenosine

Guanylyl-(3'-5')-cytidine

Uridylyl-(3'-5')-cytidine

Guanylyl-(3'-5')-guanosine

Cytidylyl-(3'-5')-cytidine

Guanylyl-(3'-5')-uridine

Adenylyl-(3'-5')-guanosine

Adenylyl-3'-5'-cytidine

Uridylyl-(3'-5')-adenosine

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