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2'-Modified Nucleotides
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(50/50) Phosphate Modified Nucleotides (93/93) Ribonucleotides
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8-Oxo-GTP
Description: 8-Oxo-GTP, a nucleotide with modifications, is a valuable tool in discovering RNA oxidative and repair mechanisms. Its versatile use also includes investigations into Alzheimer's and Parkinson's, as well as cancer. Its potential to provide antioxidant properties demonstrates promise for defending against oxidative stress in various disease states.
CAT: BRP-01611
CAS: 21238-36-8
MF: C10H16N5O15P3
MF: 539.18
Purity: ≥95% by HPLC
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
Density: 2.88±0.1 g/cm3
InChIKey: JCHLKIQZUXYLPW-UMMCILCDSA-N
Solubility: Soluble in Water
CanonicalSMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)NC2=O)O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O
IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-6,8-dioxo-1,7-dihydropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C10H16N5O15P3/c11-9-13-6-3(7(18)14-9)12-10(19)15(6)8-5(17)4(16)2(28-8)1-27-32(23,24)30-33(25,26)29-31(20,21)22/h2,4-5,8,16-17H,1H2,(H,12,19)(H,23,24)(H,25,26)(H2,20,21,22)(H3,11,13,14,18)/t2-,4-,5-,8-/m1/s1
Synonyms: 8-Oxoguanosine-5'-Triphosphate; 7,8-Dihydro-8-oxoguanosine 5'-(tetrahydrogen triphosphate); Purine-6,8(1H,9H)-dione, 2-amino-9-β-D-ribofuranosyl-, 5'-(tetrahydrogen triphosphate); 8-Ketoguanosine 5'-triphosphate
2-Fluoro-ATP
Description: 2-Fluoro-ATP is a toxic metabolite of 9-β-D-arabinosyl-2-fluoroadenine, an anticancer drug. 2-Fluoro-ATP is commonly used as a versatile tool for 19F NMR-based activity screening.
CAT: BRP-01612
CAS: 1492-62-2
MF: C10H15FN5O13P3
MF: 525.17
Purity: ≥95% by HPLC
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
Density: 2.68±0.1 g/cm3
Boiling Point: 1006.2±75.0 °C at 760 mmHg
InChIKey: PIOKUWLZUXUBCO-UUOKFMHZSA-N
Solubility: Soluble in Water
CanonicalSMILES: C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)F)N
IUPAC Name: [[(2R,3S,4R,5R)-5-(6-amino-2-fluoropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: 1S/C10H15FN5O13P3/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,17-18H,1H2,(H,22,23)(H,24,25)(H2,12,14,15)(H2,19,20,21)/t3-,5-,6-,9-/m1/s1
Synonyms: (2F-ATP); 2-Fluoro-adenosine-5'-triphosphate; 2-F-ATP; 2-Fluoroadenosine 5'-(tetrahydrogen triphosphate); Adenosine, 2-fluoro-, 5'-(tetrahydrogen triphosphate); Adenosine, 2-fluoro-, 5'-triphosphate; 2-Fluoroadenine-9β-D-ribofuranoside 5'-triphosphate; 2-Fluoroadenosine 5'-triphosphate; 2-Fluoroadenosine triphosphate
Inosine 5'-(tetrahydrogen triphosphate)
Description: Inosine 5'-(tetrahydrogen triphosphate) is a bioactive organic molecule with immense therapeutic potential in addressing an array of ailments- from cancer, metabolic afflictions, to viral infections. It functions as an indispensable precursor for purine nucleotide synthesis, thereby stimulating ATP production, augmenting cellular energy reserves, and activating immune cells such as T-cells to ramp up response to various intruders.
CAT: BRP-01613
CAS: 132-06-9
MF: C10H15N4O14P3
MF: 508.17
Purity: ≥98% by AX-HPLC
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
Density: 2.63 g/cm3
InChIKey: HAEJPQIATWHALX-KQYNXXCUSA-N
Solubility: Soluble in Water
CanonicalSMILES: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
IUPAC Name: [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C10H15N4O14P3/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
Synonyms: ITP; Hypoxanthine; Inosine-5'-Triphosphate; Inosine 5'-(tetrahydrogen triphosphate); 5'-ITP; Inosine 5'-triphosphate; Inosine triphosphate
Related CAS: 35908-31-7 (trisodium salt) ; 14356-95-7 (tetrasodium salt)
5-Fluoro-UTP
Description: 5-Fluoro-UTP is an DNA/RNA synthesis inhibitor that terminate synthesis of nucleotide through inhibiting thymidylate synthase. It is used as an anticancer drug.
CAT: BRP-01614
CAS: 3828-96-4
MF: C9H14FN2O15P3
MF: 502.13
Purity: ≥95% by HPLC
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
Density: 2.13±0.1 g/cm3
Application: 5-Fluoro-UTP is an DNA/RNA synthesis inhibitor.
InChIKey: AREUQFTVCMGENT-UAKXSSHOSA-N
Solubility: Soluble in Water
CanonicalSMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)F
IUPAC Name: [[(2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C9H14FN2O15P3/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(25-8)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1
Synonyms: (5F-UTP); 5-Fluoro-uridine-5'-triphosphate; 5-F-UTP; 5-Fluorouridine 5'-(tetrahydrogen triphosphate); Uridine, 5-fluoro-, 5'-(tetrahydrogen triphosphate); Uridine, 5-fluoro-, 5'-triphosphate; 5-Fluorouridine 5'-triphosphate; 5-Fluorouridine triphosphate; Fluorouridine triphosphate
5-Ethynyl-UTP
Description: 5-Ethynyl-UTP is a compound acting as a ubiquitous substrate to foster DNA research and development and modification.
CAT: BRP-01615
CAS: 1004955-96-7
MF: C11H15N2O15P3
MF: 508.16
Purity: ≥95% by HPLC
Appearance: Lyophilized white powder
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Storage: Store at -20°C
Density: 2.05±0.1 g/cm3
InChIKey: AGTYLGHUHWJTSE-FDDDBJFASA-N
Solubility: Soluble in Water
CanonicalSMILES: C#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
IUPAC Name: [[(2R,3S,4R,5R)-5-(5-ethynyl-2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C11H15N2O15P3/c1-2-5-3-13(11(17)12-9(5)16)10-8(15)7(14)6(26-10)4-25-30(21,22)28-31(23,24)27-29(18,19)20/h1,3,6-8,10,14-15H,4H2,(H,21,22)(H,23,24)(H,12,16,17)(H2,18,19,20)/t6-,7-,8-,10-/m1/s1
Synonyms: 5-Ethynyluridine 5'-(tetrahydrogen triphosphate); 5-Ethynyl-deoxyuridine triphosphate; 5-Ethynyl uridine-triphosphate
NHC-triphosphate
Description: N 4-Hydroxycytidine (NHC) is an antiviral ribonucleoside analog that acts as a competitive alternative substrate for virally encoded RNA-dependent RNA polymerases. NHC-triphosphate is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA.
CAT: BRP-01616
CAS: 34973-27-8
MF: C9H16N3O15P3
MF: 499.16
Purity: 98%
Appearance: White or off-white solid
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Storage: Store at -20°C
Density: 2.52±0.1 g/cm3
InChIKey: BNIQIYMICUFERK-XVFCMESISA-N
Solubility: Soluble in DMSO
CanonicalSMILES: C1=CN(C(=O)N=C1NO)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
IUPAC Name: [[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C9H16N3O15P3/c13-6-4(3-24-29(20,21)27-30(22,23)26-28(17,18)19)25-8(7(6)14)12-2-1-5(11-16)10-9(12)15/h1-2,4,6-8,13-14,16H,3H2,(H,20,21)(H,22,23)(H,10,11,15)(H2,17,18,19)/t4-,6-,7-,8-/m1/s1
Synonyms: N4-Hydroxycytidine 5'-triphosphate; N4-hydroxy-CTP; Uridine 5'-(tetrahydrogen triphosphate), 4-oxime; Uridine, 4-oxime, 5'-triphosphate; 1-β-D-Ribofuranosyl-4-hydroxylamino-2-pyrimidinone 5'-triphosphate; EIDD 2061; EIDD-1931 triphosphate; N4-Hydroxycytidine triphosphate
Isocytidine triphosphate
Description: Isocytidine Triphosphate is an essential biochemical compound for disease research and nucleotide metabolism studies, serving as an indispensable precursor for synthesizing nucleotides bustling with isocytidine. Embedded within the intricate tapestry of DNA and RNA metabolism, these nucleotides emerge as cornerstones, intricately involved in studying viral infections and navigating genetic disorders.
CAT: BRP-01618
CAS: 150668-55-6
MF: C9H16N3O14P3
MF: 483.16
Purity: >95%
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
Density: 2.50±0.1 g/cm3
Boiling Point: 849.2±75.0°C at 760 mmHg
InChIKey: MIJSFJCPGQQTMK-XVFCMESISA-N
Solubility: Soluble in Water
CanonicalSMILES: C1=CN(C(=NC1=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-4-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C9H16N3O14P3/c10-9-11-5(13)1-2-12(9)8-7(15)6(14)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,14-15H,3H2,(H,19,20)(H,21,22)(H2,10,11,13)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
Synonyms: 4(1H)-Pyrimidinone, 2-amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-; 2-Amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-4(1H)-pyrimidinone; ((2R,3S,4R,5R)-5-(2-amino-4-oxopyrimidin-1(4H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; isoCTP
Guanosine-5'-O-(2-thiodiphosphate)
Description: GDP-βS is guanosine 5'-O-(2-thiodiphosphate), a modified form of guanosine diphosphate (GDP) where the oxygen in the β-phosphate position is replaced by a sulfur atom. It is commonly used as a non-hydrolyzable analog of GDP in biochemical studies to investigate GTPase activity, signal transduction pathways, and molecular mechanisms involving GTP-binding proteins (G proteins).
CAT: BRP-01645
CAS: 71376-97-1
MF: C10H15N5O10P2S
MF: 459.27
Purity: ≥90% by HPLC
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Storage: Store at -20 °C, Always avoid freeze-thaw cycles
Density: 2.55±0.1 g/cm3
Boiling Point: 901.1±75.0 °C at 760 mmHg
InChIKey: QJXJXBXFIOTYHB-UUOKFMHZSA-N
CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=S)(O)O)O)O)N=C(NC2=O)N
IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydroxyphosphinothioyl hydrogen phosphate
InChI: InChI=1S/C10H15N5O10P2S/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(24-9)1-23-26(19,20)25-27(21,22)28/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H2,21,22,28)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
Synonyms: 5'-Guanylic acid, anhydride with phosphorothioic acid (1:1); 5'-Guanylic acid, monoanhydride with phosphorothioic acid; GDP-βS; Guanosine 5'-(β-thiodiphosphate); Guanosine 5'-O-(2-thiodiphosphate); Guanosine 5'-O-(β-thiodiphosphate); Guanyl-5'-yl thiophosphate
Related CAS: 97952-36-8 (trilithium salt) ; 2179317-10-1 (x-ammonium salt) ; 906735-10-2 (triethylamine salt (1:x)) ; 948028-69-1 (triethylamine salt (1:1)) ; 1397700-13-8 (triethylamine salt (1:3))
7-Methyl-guanosine-5'-monophosphate, triethylamine salt
Description: 7-Methyl-guanosine-5'-monophosphate, triethylamine salt, is a nucleotide where 7-methyl-guanosine, a modified nucleoside, is phosphorylated at the 5' position and combined with triethylamine to form its salt. 7-Methyl-guanosine-5'-monophosphate, triethylamine salt, can be used in research involving RNA capping mechanisms, RNA modification and structure, RNA-protein interactions, and the role of modified nucleosides in RNA stability and function. It is also useful in studies aiming to understand the biochemistry of RNA and its various modifications.
CAT: BRP-01646
MF: C11H16N5O8P (free acid)
MF: 377.25 (free acid)
Purity: ≥95% by HPLC
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IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate;N,N-diethylethanamine
Synonyms: N1-methyl-guanosine-5'-monophosphate, triethylamine salt; N7-Me-GMP TEA salt; N(7)-methylguanosine 5'-phosphate triethylamine salt; 7-Methyl-5'-guanylic acid inner salt, triethylamine salt; 2-Amino-1,6-dihydro-7-methyl-6-oxo-9-beta-D-ribofuranosylpurinium hydroxide, 5'-phosphate, inner salt, triethylamine salt; 7-Methylguanosine-5'-monophosphate, triethylamine salt
Related CAS: 10162-58-0 (free base)
5-Methylcytidine-5'-monophosphate
Description: 5-methylcytidine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate having 5-methylcytosine as the nucleobase. It derives from a cytidine 5'-monophosphate.
CAT: BRP-01647
CAS: 3590-36-1
MF: C10H16N3O8P
MF: 337.22
Purity: ≥95% by HPLC
Appearance: White to Off-white Powder
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Storage: Store at -20°C
Density: 2.04±0.1 g/cm3
Boiling Point: 666.5±65.0°C at 760 mmHg
InChIKey: NJQONZSFUKNYOY-JXOAFFINSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O
IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
InChI: InChI=1S/C10H16N3O8P/c1-4-2-13(10(16)12-8(4)11)9-7(15)6(14)5(21-9)3-20-22(17,18)19/h2,5-7,9,14-15H,3H2,1H3,(H2,11,12,16)(H2,17,18,19)/t5-,6-,7-,9-/m1/s1
Synonyms: 5-Methyl-cytidine-5'-monophosphate, free acid; 5-Me-CMP.H2; 5-Me-CMP; 5-Methyl-CMP; m5CMP; 5-Methylcytidylic acid; 5-methylcytidine 5'-(dihydrogen phosphate); ((2R,3S,4R,5R)-5-(4-Amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate; Cytidine, 5-methyl-, 5'-(dihydrogen phosphate)
Related CAS: 117309-80-5 (ammonium salt)
6-Chloroinosine monophosphate
Description: 6-Chloroinosine monophosphate is a derivative of inosine monophosphate (IMP) where a chlorine atom is substituted at the 6th position of the purine ring. This modified nucleotide analog is utilized in biochemical and molecular biology research for probing nucleic acid structure, enzymatic reactions, and as a substrate for various enzymes. It can also serve as a precursor for the synthesis of modified nucleic acids for studying structure-function relationships or for therapeutic applications.
CAT: BRP-01648
CAS: 5843-59-4
MF: C10H12ClN4O7P
MF: 366.65
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InChIKey: ALOBOMYIOYNCBS-KQYNXXCUSA-N
CanonicalSMILES: C1=NC2=C(C(=N1)Cl)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O
IUPAC Name: [(2R,3S,4R,5R)-5-(6-chloropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
InChI: InChI=1S/C10H12ClN4O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
Synonyms: 6-Cl-adenosine-5'-monophosphate; 6-Cl-AMP; 6-Cl-Purine Ribotide; 6-Chloropurine riboside 5'-monophosphate; 6-Chloropurine ribotide; 6-Chloropurine riboside 5'-phosphate; 6-Chloropurine 9-beta-D-ribofuranosyl 5'-monophosphate; 6-Chloro-9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purine; ((2R,3S,4R,5R)-5-(6-Chloro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
8-Bromo-cAMP sodium salt
Description: 8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA. It inhibits cell growth, decreases proliferation, increases differentiation and induces apoptosis.
CAT: BRP-01649
CAS: 76939-46-3
MF: C10H10BrN5NaO6P
MF: 430.08
Purity: ≥95% by HPLC
Appearance: Off-white powder
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Storage: Store at -20 °C
Shelf Life: 2 years if stored properly
InChIKey: DMRMZQATXPQOTP-GWTDSMLYSA-M
Solubility: Soluble in DMSO, Ethanol, Water
CanonicalSMILES: C1C2C(C(C(O2)N3C4=NC=NC(=C4N=C3Br)N)O)OP(=O)(O1)[O-].[Na+]
IUPAC Name: sodium;(4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
InChI: InChI=1S/C10H11BrN5O6P.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1
Synonyms: 8-Br-3',5'-cyclo-adenosine monophosphate, sodium salt; 8-Br-3',5'-cyclo-AMP.Na; (8Br-cAMP) sodium salt; 8-Bromo-adenosine-3',5'-cyclic monophosphate, Sodium salt; 8-Br-cAMP sodium salt; 8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt; Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate), sodium salt (1:1)
Related CAS: 23583-48-4 (free acid)
2'-O-Methylguanosine 5'-monophosphate
Description: 2'-O-Methylguanosine 5'-monophosphate triethylammonium salt is a critical compound extensively used in the biomedical industry. It plays a crucial role in the treatment and research of various diseases, including viral infections, cancer, and neurological disorders. This product contributes to the development of targeted therapies and is an essential component in nucleic acid-based drug formulations. Its high purity and quality make it a valuable tool for biomedical research and drug discovery.
CAT: BRP-01650
CAS: 24121-01-5
MF: C11H16N5O8P
MF: 377.25
Purity: ≥95% by HPLC
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Storage: Store at 2-8 °C, Keep in a dark and dry place
Density: 2.20±0.10 g/cm3
InChIKey: YPMKZCOIEXUDSS-KQYNXXCUSA-N
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=O)(O)O)O
IUPAC Name: [(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methyl dihydrogen phosphate
InChI: InChI=1S/C11H16N5O8P/c1-22-7-6(17)4(2-23-25(19,20)21)24-10(7)16-3-13-5-8(16)14-11(12)15-9(5)18/h3-4,6-7,10,17H,2H2,1H3,(H2,19,20,21)(H3,12,14,15,18)/t4-,6-,7-,10-/m1/s1
Synonyms: 2'-O-Methyl-5'-guanylic acid; 2'-O-Mgmp; 2'-O-Methyl-guanosine 5'-monophosphate; 2'-O-Me-GMP; 2'-O-Methylguanosine 5'-(dihydrogen phosphate)
Related CAS: 28998-31-4 (monoammonium salt) ; 666720-92-9 (TEA salt)
UTPγS
Description: UTPγS is a nucleotide analog widely used in biomedical research. It serves as a substrate for enzymes involved in RNA synthesis and modification. UTPγS is employed in studies investigating RNA structure, RNA-protein interactions, and ribozyme activities. It finds applications in the exploration of RNA-based therapeutics and drug development targeting infectious diseases.
CAT: BRP-01651
CAS: 79049-97-1
MF: C9H15N2O14P3S
MF: 500.20
Purity: ≥95% by HPLC
Appearance: solid
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Storage: Store at -20 °C
InChIKey: DUDALCZPYHIGIR-XVFCMESISA-N
CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=S)(O)O)O)O
IUPAC Name: dihydroxyphosphinothioyl [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate
InChI: InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(23-8)3-22-26(16,17)24-27(18,19)25-28(20,21)29/h1-2,4,6-8,13-14H,3H2,(H,16,17)(H,18,19)(H,10,12,15)(H2,20,21,29)/t4-,6-,7-,8-/m1/s1
Synonyms: Uridine-5'-(γ-thio)-triphosphate; Uridine-5'-O-(γ-Thio)-triphosphate; UTP-γS; Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid; UTP-Gamma-S; Uridine 5'-O-(3-thiotriphosphate)
Related CAS: 1266569-94-1 (trisodium salt)
UTPγS trisodium salt
Description: UTPγS trisodium salt is a selective P2Y2 and P2Y4 receptor agonist.
CAT: BRP-01652
CAS: 1266569-94-1
MF: C9H12N2Na3O14P3S
MF: 566.15
Purity: ≥95% by HPLC
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Storage: Store at -20 °C
InChIKey: DBXMFBSCFRDIOA-LLWADOMFSA-K
CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=S)(O)[O-])O)O.[Na+].[Na+].[Na+]
IUPAC Name: trisodium;[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [hydroxy(oxido)phosphinothioyl] phosphate
InChI: InChI=1S/C9H15N2O14P3S.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(23-8)3-22-26(16,17)24-27(18,19)25-28(20,21)29;;;/h1-2,4,6-8,13-14H,3H2,(H,16,17)(H,18,19)(H,10,12,15)(H2,20,21,29);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
Synonyms: Trisodium ({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)({[hydroxy(oxido)sulfanylidene-|E-phosphanyl]oxy})phosphinate; Uridine-5'-(γ-thio)-triphosphate trisodium salt; UTP-γS trisodium salt; Uridine 5'-O-(3-thiotriphosphate) trisodium salt
Related CAS: 79049-97-1 (free acid)
2'-O-Methylguanosine-5'-triphosphate trilithium salt
Description: 2'-O-Methylguanosine-5'-triphosphate trilithium salt, a highly versatile compound, can be employed as an efficient probe for investigating RNA metabolism. It possesses the remarkable capability of obstructing RNA chain elongation, thus making it an invaluable research tool in the field. In addition to its chain terminating property, it also exhibits remarkable affinity with RNA-binding proteins and catalytic ribozymes, rendering it ideal for studying complex RNA-protein interactions and enzymatic activities.
CAT: BRP-01653
MF: C11H15Li3N5O14P3
MF: 555.00
Purity: ≥97% by HPLC
Appearance: Clear colorless liquid
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Storage: Store at -20 °C
InChIKey: DNABKBYLELJGQR-MSQVLRTGSA-K
CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O
IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
InChI: InChI=1S/C11H18N5O14P3.3Li/c1-26-7-6(17)4(2-27-32(22,23)30-33(24,25)29-31(19,20)21)28-10(7)16-3-13-5-8(16)14-11(12)15-9(5)18;;;/h3-4,6-7,10,17H,2H2,1H3,(H,22,23)(H,24,25)(H2,19,20,21)(H3,12,14,15,18);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1
Synonyms: 2'-O-Me-GTP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate
Related CAS: 61556-44-3 (free acid)
2'-O-Methyladenosine-5'-triphosphate trilithium salt
Description: 2'-O-Methyladenosine-5'-triphosphate trilithium salt, a prominent nucleotide analog in enzymatic assays detecting ATP-utilizing proteins, and in RNA structure/function studies, specific to RNA modification and translation analysis, showcases its multifarious and intriguing features. Its utilization in diverse experimental applications underlines its enormous potential and capacity to facilitate cutting-edge researches in biomedical and pharmaceutical sciences.
CAT: BRP-01654
MF: C11H15Li3N5O13P3
MF: 539.00
Purity: ≥97% by HPLC
Appearance: Clear colorless liquid
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Storage: Store at -20 °C
InChIKey: QIQIMTPLFXIYPZ-MTQUBGKESA-K
CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=NC3=C(N=CN=C32)N)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O
IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
InChI: InChI=1S/C11H18N5O13P3.3Li/c1-25-8-7(17)5(2-26-31(21,22)29-32(23,24)28-30(18,19)20)27-11(8)16-4-15-6-9(12)13-3-14-10(6)16;;;/h3-5,7-8,11,17H,2H2,1H3,(H,21,22)(H,23,24)(H2,12,13,14)(H2,18,19,20);;;/q;3*+1/p-3/t5-,7-,8-,11-;;;/m1.../s1
Synonyms: 2'-O-methyl-adenosine-5'-triphosphate, lithium salt; 2'-O-Me-ATP Lithium Salt; lithium ((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 2'-O-Me-ATP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methyladenosine; Adenosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3)
Related CAS: 30948-06-2 (free acid) ; 100020-58-4 (tetrasodium salt)
2'-O-Methylcytidine-5'-triphosphate trilithium salt
Description: 2'-O-Methylcytidine-5'-triphosphate trilithium salt, a nucleotide derivative employed frequently in RNA biosynthesis and modification investigations, holds immense promise in cancer therapies, especially as a competitive inhibitor of RNA polymerase II elongation. Compelling evidence also demonstrates its success as an inhibitor of viral replication, particularly in the context of hepatitis C.
CAT: BRP-01655
MF: C10H15Li3N3O14P3
MF: 514.98
Purity: ≥97% by HPLC
Appearance: Clear colorless liquid
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Storage: Store at -20 °C
InChIKey: RIFSDAPMKYBRDH-WKMNQBAXSA-K
CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=CC(=NC2=O)N)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O
IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
InChI: InChI=1S/C10H18N3O14P3.3Li/c1-23-8-7(14)5(25-9(8)13-3-2-6(11)12-10(13)15)4-24-29(19,20)27-30(21,22)26-28(16,17)18;;;/h2-3,5,7-9,14H,4H2,1H3,(H,19,20)(H,21,22)(H2,11,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t5-,7-,8-,9-;;;/m1.../s1
Synonyms: 2'-O-methyl-cytidine-5'-triphosphate, lithium salt; 2'-O-Me-CTP Lithium Salt; 2'-O-Me-CTP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methylcytidine; Cytidine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 2'-O-methyl-Cytidine-5'-triphosphate, trilithium salt
Related CAS: 143028-98-2 (free acid)
2'-O-Methyluridine-5'-triphosphate trilithium salt
Description: 2'-O-Methyluridine-5'-triphosphate trilithium salt, a biochemical reagent widely applied in biomedicine to investigate RNA transcription and modification, is a valuable research tool with incomparable properties that afford an accurate insight of cellular processes related to RNA function and modification. Scientists favor its use as a substrate for RNA polymerase, that enables them to scrutinize RNA synthesis and modification of transcripts. Furthermore, this trilithium salt is constructive in analyzing RNA-protein interactions and probing ribozymes.
CAT: BRP-01656
MF: C10H14Li3N2O15P3
MF: 515.96
Purity: ≥97% by HPLC
Appearance: Clear colorless liquid
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Storage: Store at -20 °C
InChIKey: ZBEHXEVNNHLIAB-WKMNQBAXSA-K
CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=CC(=O)NC2=O)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O
IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
InChI: InChI=1S/C10H17N2O15P3.3Li/c1-23-8-7(14)5(25-9(8)12-3-2-6(13)11-10(12)15)4-24-29(19,20)27-30(21,22)26-28(16,17)18;;;/h2-3,5,7-9,14H,4H2,1H3,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18);;;/q;3*+1/p-3/t5-,7-,8-,9-;;;/m1.../s1
Synonyms: 2'-O-Methyl-uridine-5'-triphosphate, lithium salt; 2'-O-Me-UTP Lithium Salt; lithium ((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 2'-OMe-UTP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methyluridine; Uridine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); 2'-methoxy-UTP trilithium salt; 2'-O-methyl-Uridine-5'-triphosphate, trilithium salt; 2'-OMe-UTP.Li3
Related CAS: 143028-99-3 (free acid)
2'-O-Methyluridine-5'-triphosphate
Description: 2'-O-Methyluridine-5'-triphosphate is a nucleotide analog commonly used in biochemistry research. It can be used as a substrate for RNA polymerases or as a terminoligical ATP analog for use in RNA synthesis reactions. Its effectiveness as an antiviral and antitumor agent is also being investigated.
CAT: BRP-01657
CAS: 143028-99-3
MF: C10H17N2O15P3
MF: 498.17
Purity: ≥97% by HPLC
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Storage: Store at -20 °C
Density: 2.0±0.1 g/cm3
InChIKey: BQJWHJWAEOHVCK-ZOQUXTDFSA-N
CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
IUPAC Name: [[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C10H17N2O15P3/c1-23-8-7(14)5(25-9(8)12-3-2-6(13)11-10(12)15)4-24-29(19,20)27-30(21,22)26-28(16,17)18/h2-3,5,7-9,14H,4H2,1H3,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18)/t5-,7-,8-,9-/m1/s1
Synonyms: 2'-methoxy-UTP; 2'-O-Methyluridine 5'-triphosphoric acid; uridine 5'-(tetrahydrogen triphosphate), 2'-O-methyl-; 5'-(tetrahydrogen triphosphate), 2'-O-methyl-Uridine; 2'-O-Methyluridine 5'-(tetrahydrogen triphosphate); 2'-O-Me-UTP; 2'-OMe-UTP
