Nucleotides

Inosine 5'-monophosphate monopotassium salt

Description: Inosine 5'-monophosphate monopotassium salt (IMP-K) is a valuable nucleotide derivative used in biochemical, pharmacological, and nutritional research. Its role in nucleotide metabolism makes it an important substrate for enzyme studies and drug development. Additionally, its application as a flavor enhancer highlights its versatility in both scientific and industrial contexts. This compound provides insights into purine metabolism and aids in the development of therapeutic agents targeting related metabolic pathways.

CAT: BRP-01503

CAS: 909272-79-3

Molecular Formula: C10H12KN4O8P

Molecular Weight: 386.30

Purity: 98%

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InChIKey: AWOLVHQZOSVDSL-MCDZGGTQSA-M

CanonicalSMILES: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)[O-])O)O.[K+]

IUPAC Name: potassium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl hydrogen phosphate

InChI: InChI=1S/C10H13N4O8P.K/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1

Synonyms: 5'-Inosinic acid, potassium salt (1:1); Inosinic acid, potassium salt; IMP potassium salt; 5'-IMP potassium salt; Inosine 5'-(dihydrogen phosphate) potassium salt; Inosine 5'-phosphate potassium salt; Inosine-5'-monophosphoric acid potassium salt; ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl hydrogen phosphate potassium salt; Inosine 5'-monophosphate potassium salt

Related CAS: 20262-26-4 (dipotassium salt) ; 96286-05-4 (x-potassium salt) ; 131-99-7 (free acid)

2'-F-m7GMP sodium salt

Description: 2'-F-m7GMP sodium salt is a modified nucleotide derivative used in biochemical and pharmaceutical research. It consists of 7-methylguanosine monophosphate (m7GMP) with a fluorine substitution at the 2' carbon of the ribose sugar, and it is in its sodium salt form for improved solubility and stability in aqueous solutions. This compound is primarily employed to investigate RNA modifications and their biological implications. The fluorine substitution at the 2' position can potentially alter the base-pairing properties and interactions of the nucleotide with RNA-binding proteins or enzymes involved in RNA metabolism. It serves as a valuable tool in studies aiming to understand the role of modified nucleotides in gene expression regulation, RNA structure-function relationships, and as a potential therapeutic target in RNA-related diseases.

CAT: BRP-01536

Molecular Formula: C11H15FN5O7P (free acid)

Molecular Weight: 379.24 (free acid)

Purity: >98%

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

Synonyms: ((2R,3R,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate sodium salt; 5'-Guanylic acid, 7-methyl-2'-deoxy-2'-fluoro-, inner salt, sodium salt

2'-F-m7GMP ammonium salt

Description: 2'-F-m7GMP ammonium salt is a modified nucleotide derivative used in biochemical and pharmaceutical research. It consists of 7-methylguanosine monophosphate (m7GMP) with a fluorine substitution at the 2' carbon of the ribose sugar, and it is in its ammonium salt form for improved solubility and stability in aqueous solutions. This compound is primarily employed to investigate RNA modifications and their biological implications. The fluorine substitution at the 2' position can potentially alter the base-pairing properties and interactions of the nucleotide with RNA-binding proteins or enzymes involved in RNA metabolism. It serves as a valuable tool in studies aiming to understand the role of modified nucleotides in gene expression regulation, RNA structure-function relationships, and as a potential therapeutic target in RNA-related diseases.

CAT: BRP-01537

Molecular Formula: C11H15FN5O7P (free acid)

Molecular Weight: 379.24 (free acid)

Purity: >98%

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

Synonyms: 5'-Guanylic acid, 7-methyl-2'-deoxy-2'-fluoro-, inner salt, ammonium salt; ((2R,3R,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate ammonium salt

2'-F-m7GMP TEA Salt

Description: 2'-F-m7GMP TEA Salt is a modified nucleotide derivative used in biochemical and pharmaceutical research. It consists of 7-methylguanosine monophosphate (m7GMP) with a fluorine substitution at the 2' carbon of the ribose sugar, and it is in its TEA salt form for improved solubility and stability in aqueous solutions. This compound is primarily employed to investigate RNA modifications and their biological implications. The fluorine substitution at the 2' position can potentially alter the base-pairing properties and interactions of the nucleotide with RNA-binding proteins or enzymes involved in RNA metabolism. It serves as a valuable tool in studies aiming to understand the role of modified nucleotides in gene expression regulation, RNA structure-function relationships, and as a potential therapeutic target in RNA-related diseases.

CAT: BRP-01538

Molecular Formula: C11H15FN5O7P (free base)

Molecular Weight: 379.24 (free base)

Purity: >98%

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

Synonyms: 5'-Guanylic acid, 7-methyl-2'-deoxy-2'-fluoro-, inner salt, triethylammonium salt; ((2R,3R,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate triethylammonium salt

2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, ammonium salt

Description: 2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, ammonium salt is a modified nucleotide derivative utilized in molecular biology research to introduce modified nucleotides into DNA and RNA molecules. Its unique structure, featuring fluorine and methyl substitutions on the ribose sugar of uridine, enhances stability and resistance to enzymatic degradation, making it valuable for studying nucleic acid structure, function, and interactions. This modified nucleotide serves as a substrate for DNA and RNA polymerases, facilitating the synthesis of modified nucleic acids and enabling the development of novel molecular tools and techniques in genetic engineering and RNA biology research.

CAT: BRP-01549

Molecular Formula: C10H28FN6O14P3

Molecular Weight: 568.28

Purity: ≥98% by HPLC

Appearance: White powder

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Storage: Store at -20 °C

InChIKey: GXUQVMFGQHPIPU-DLULJLDFSA-N

CanonicalSMILES: O=C1C=CN(C(=O)N1)C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2(F)C.[NH4+].[NH4+].[NH4+].[NH4+]

IUPAC Name: tetraammonium;((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl triphosphate

InChI: InChI=1S/C10H16FN2O14P3.4H3N/c1-10(11)7(15)5(25-8(10)13-3-2-6(14)12-9(13)16)4-24-29(20,21)27-30(22,23)26-28(17,18)19;;;;/h2-3,5,7-8,15H,4H2,1H3,(H,20,21)(H,22,23)(H,12,14,16)(H2,17,18,19);4*1H3/t5-,7-,8-,10-;;;;/m1..../s1

Synonyms: 2'-F-2'-C-Me-dUTP.4NH4; (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine 5'-(tetrahydrogen triphosphate) ammonium salt; GS 461203 ammonium salt; PSI 7409 ammonium salt; Sofosbuvir triphosphate ammonium salt; Sofosbuvir-TP ammonium salt

Related CAS: 1015073-42-3 (free acid)

2'-Fluoro-2'-deoxyguanosine-5'-monophosphate, disodium salt

Description: 2'-Fluoro-2'-deoxyguanosine-5'-monophosphate, disodium salt is a modified nucleotide derivative used in biochemical and molecular biology research. It is valuable in studying nucleotide metabolism, nucleic acid-protein interactions, and RNA biology, contributing to advancements in genetic engineering, drug discovery, and molecular diagnostics.

CAT: BRP-01550

Molecular Formula: C10H11FN5Na2O7P

Molecular Weight: 409.18

Purity: ≥98% by HPLC

Appearance: White powder

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Storage: Store at -20 °C

InChIKey: KUVAIZOIRVHUFK-ZOYUQYBOSA-L

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)[O-])O)F)N=C(N=C2[O-])N.[Na+].[Na+]

IUPAC Name: disodium;((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl phosphate

InChI: InChI=1S/C10H13FN5O7P.2Na/c11-4-6(17)3(1-22-24(19,20)21)23-9(4)16-2-13-5-7(16)14-10(12)15-8(5)18;;/h2-4,6,9,17H,1H2,(H2,19,20,21)(H3,12,14,15,18);;/q;2*+1/p-2/t3-,4-,6-,9-;;/m1../s1

Synonyms: 2'-F-dGMP.Na2; 2'-F-dGMP disodium salt; 2'-Deoxy-2'-fluoroguanosine-5'-monophosphate disodium salt; 9-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)guanine-5'-monophosphate disodium salt; 2'-deoxy-2'-fluoroguanosine 5'-(dihydrogen phosphate) disodium salt

Related CAS: 170784-58-4 (free acid)

Iso-GTP

Description: Iso-GTP, also known as iso-guanosine triphosphate, is a modified nucleotide used in biochemical and molecular biology research. It features an isomer of guanosine linked to a triphosphate group. Iso-GTP can be incorporated into RNA or DNA strands during synthesis, providing a means to study the effects of nucleotide isomerism on nucleic acid structure, function, and interactions. This compound is useful in investigations of nucleotide analogs' roles in enzymatic processes, molecular recognition, and potential therapeutic applications. Its unique structural properties allow researchers to explore variations in nucleotide behavior and stability compared to natural guanosine triphosphate (GTP).

CAT: BRP-01608

CAS: 58083-93-5

Molecular Formula: C10H16N5O14P3

Molecular Weight: 523.18

Purity: 95%

Appearance: Lyophilized white powder

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Storage: Store at -20°C

Density: 2.75±0.1 g/cm3

InChIKey: DJHOBIUAJLDRDQ-UUOKFMHZSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=NC2=C(NC(=O)N=C2N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

IUPAC Name: [[(2R,3S,4R,5R)-5-(6-amino-2-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H16N5O14P3/c11-7-4-8(14-10(18)13-7)15(2-12-4)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1

Synonyms: Adenosine 5'-(tetrahydrogen triphosphate), 2,3-dihydro-2-oxo-; 2,3-Dihydro-2-oxoadenosine 5'-(tetrahydrogen triphosphate); Adenosine 5'-(tetrahydrogen triphosphate), 1,2-dihydro-2-oxo-; iso-GTP; Isoguanosine 5'-triphosphate; 2-hydroxy-ATP; 2-oxo-2-hydroadenosine 5'-(tetrahydrogen triphosphate); isoGTP; (((2R,3S,4R,5R)-5-(6-amino-2-oxo-1,2-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid

Related CAS: 148469-19-6 (tetraammonium salt)

8-Oxo-GTP

Description: 8-Oxo-GTP, a nucleotide with modifications, is a valuable tool in discovering RNA oxidative and repair mechanisms. Its versatile use also includes investigations into Alzheimer's and Parkinson's, as well as cancer. Its potential to provide antioxidant properties demonstrates promise for defending against oxidative stress in various disease states.

CAT: BRP-01611

CAS: 21238-36-8

Molecular Formula: C10H16N5O15P3

Molecular Weight: 539.18

Purity: ≥95% by HPLC

Appearance: Lyophilized white powder

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Storage: Store at -20 °C

Density: 2.88±0.1 g/cm3

InChIKey: JCHLKIQZUXYLPW-UMMCILCDSA-N

Solubility: Soluble in Water

CanonicalSMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)NC2=O)O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-6,8-dioxo-1,7-dihydropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H16N5O15P3/c11-9-13-6-3(7(18)14-9)12-10(19)15(6)8-5(17)4(16)2(28-8)1-27-32(23,24)30-33(25,26)29-31(20,21)22/h2,4-5,8,16-17H,1H2,(H,12,19)(H,23,24)(H,25,26)(H2,20,21,22)(H3,11,13,14,18)/t2-,4-,5-,8-/m1/s1

Synonyms: 8-Oxoguanosine-5'-Triphosphate; 7,8-Dihydro-8-oxoguanosine 5'-(tetrahydrogen triphosphate); Purine-6,8(1H,9H)-dione, 2-amino-9-β-D-ribofuranosyl-, 5'-(tetrahydrogen triphosphate); 8-Ketoguanosine 5'-triphosphate

2-Fluoro-ATP

Description: 2-Fluoro-ATP is a toxic metabolite of 9-β-D-arabinosyl-2-fluoroadenine, an anticancer drug. 2-Fluoro-ATP is commonly used as a versatile tool for 19F NMR-based activity screening.

CAT: BRP-01612

CAS: 1492-62-2

Molecular Formula: C10H15FN5O13P3

Molecular Weight: 525.17

Purity: ≥95% by HPLC

Appearance: Lyophilized white powder

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Storage: Store at -20 °C

Density: 2.68±0.1 g/cm3

Boiling Point: 1006.2±75.0 °C at 760 mmHg

InChIKey: PIOKUWLZUXUBCO-UUOKFMHZSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)F)N

IUPAC Name: [[(2R,3S,4R,5R)-5-(6-amino-2-fluoropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: 1S/C10H15FN5O13P3/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,17-18H,1H2,(H,22,23)(H,24,25)(H2,12,14,15)(H2,19,20,21)/t3-,5-,6-,9-/m1/s1

Synonyms: (2F-ATP); 2-Fluoro-adenosine-5'-triphosphate; 2-F-ATP; 2-Fluoroadenosine 5'-(tetrahydrogen triphosphate); Adenosine, 2-fluoro-, 5'-(tetrahydrogen triphosphate); Adenosine, 2-fluoro-, 5'-triphosphate; 2-Fluoroadenine-9β-D-ribofuranoside 5'-triphosphate; 2-Fluoroadenosine 5'-triphosphate; 2-Fluoroadenosine triphosphate

Inosine 5'-(tetrahydrogen triphosphate)

Description: Inosine 5'-(tetrahydrogen triphosphate) is a bioactive organic molecule with immense therapeutic potential in addressing an array of ailments- from cancer, metabolic afflictions, to viral infections. It functions as an indispensable precursor for purine nucleotide synthesis, thereby stimulating ATP production, augmenting cellular energy reserves, and activating immune cells such as T-cells to ramp up response to various intruders.

CAT: BRP-01613

CAS: 132-06-9

Molecular Formula: C10H15N4O14P3

Molecular Weight: 508.17

Purity: ≥98% by AX-HPLC

Appearance: Lyophilized white powder

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Storage: Store at -20 °C

Density: 2.63 g/cm3

InChIKey: HAEJPQIATWHALX-KQYNXXCUSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H15N4O14P3/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

Synonyms: ITP; Hypoxanthine; Inosine-5'-Triphosphate; Inosine 5'-(tetrahydrogen triphosphate); 5'-ITP; Inosine 5'-triphosphate; Inosine triphosphate

Related CAS: 35908-31-7 (trisodium salt) ; 14356-95-7 (tetrasodium salt)

5-Fluoro-UTP

Description: 5-Fluoro-UTP is an DNA/RNA synthesis inhibitor that terminate synthesis of nucleotide through inhibiting thymidylate synthase. It is used as an anticancer drug.

CAT: BRP-01614

CAS: 3828-96-4

Molecular Formula: C9H14FN2O15P3

Molecular Weight: 502.13

Purity: ≥95% by HPLC

Appearance: Lyophilized white powder

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Storage: Store at -20 °C

Density: 2.13±0.1 g/cm3

Application: 5-Fluoro-UTP is an DNA/RNA synthesis inhibitor.

InChIKey: AREUQFTVCMGENT-UAKXSSHOSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)F

IUPAC Name: [[(2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H14FN2O15P3/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(25-8)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1

Synonyms: (5F-UTP); 5-Fluoro-uridine-5'-triphosphate; 5-F-UTP; 5-Fluorouridine 5'-(tetrahydrogen triphosphate); Uridine, 5-fluoro-, 5'-(tetrahydrogen triphosphate); Uridine, 5-fluoro-, 5'-triphosphate; 5-Fluorouridine 5'-triphosphate; 5-Fluorouridine triphosphate; Fluorouridine triphosphate

5-Ethynyl-UTP

Description: 5-Ethynyl-UTP is a compound acting as a ubiquitous substrate to foster DNA research and development and modification.

CAT: BRP-01615

CAS: 1004955-96-7

Molecular Formula: C11H15N2O15P3

Molecular Weight: 508.16

Purity: ≥95% by HPLC

Appearance: Lyophilized white powder

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Storage: Store at -20°C

Density: 2.05±0.1 g/cm3

InChIKey: AGTYLGHUHWJTSE-FDDDBJFASA-N

Solubility: Soluble in Water

CanonicalSMILES: C#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(5-ethynyl-2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C11H15N2O15P3/c1-2-5-3-13(11(17)12-9(5)16)10-8(15)7(14)6(26-10)4-25-30(21,22)28-31(23,24)27-29(18,19)20/h1,3,6-8,10,14-15H,4H2,(H,21,22)(H,23,24)(H,12,16,17)(H2,18,19,20)/t6-,7-,8-,10-/m1/s1

Synonyms: 5-Ethynyluridine 5'-(tetrahydrogen triphosphate); 5-Ethynyl-deoxyuridine triphosphate; 5-Ethynyl uridine-triphosphate

NHC-triphosphate

Description: N 4-Hydroxycytidine (NHC) is an antiviral ribonucleoside analog that acts as a competitive alternative substrate for virally encoded RNA-dependent RNA polymerases. NHC-triphosphate is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA.

CAT: BRP-01616

CAS: 34973-27-8

Molecular Formula: C9H16N3O15P3

Molecular Weight: 499.16

Purity: 98%

Appearance: White or off-white solid

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Storage: Store at -20°C

Density: 2.52±0.1 g/cm3

InChIKey: BNIQIYMICUFERK-XVFCMESISA-N

Solubility: Soluble in DMSO

CanonicalSMILES: C1=CN(C(=O)N=C1NO)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H16N3O15P3/c13-6-4(3-24-29(20,21)27-30(22,23)26-28(17,18)19)25-8(7(6)14)12-2-1-5(11-16)10-9(12)15/h1-2,4,6-8,13-14,16H,3H2,(H,20,21)(H,22,23)(H,10,11,15)(H2,17,18,19)/t4-,6-,7-,8-/m1/s1

Synonyms: N4-Hydroxycytidine 5'-triphosphate; N4-hydroxy-CTP; Uridine 5'-(tetrahydrogen triphosphate), 4-oxime; Uridine, 4-oxime, 5'-triphosphate; 1-β-D-Ribofuranosyl-4-hydroxylamino-2-pyrimidinone 5'-triphosphate; EIDD 2061; EIDD-1931 triphosphate; N4-Hydroxycytidine triphosphate

Isocytidine triphosphate

Description: Isocytidine Triphosphate is an essential biochemical compound for disease research and nucleotide metabolism studies, serving as an indispensable precursor for synthesizing nucleotides bustling with isocytidine. Embedded within the intricate tapestry of DNA and RNA metabolism, these nucleotides emerge as cornerstones, intricately involved in studying viral infections and navigating genetic disorders.

CAT: BRP-01618

CAS: 150668-55-6

Molecular Formula: C9H16N3O14P3

Molecular Weight: 483.16

Purity: >95%

Appearance: Lyophilized white powder

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Storage: Store at -20 °C

Density: 2.50±0.1 g/cm3

Boiling Point: 849.2±75.0°C at 760 mmHg

InChIKey: MIJSFJCPGQQTMK-XVFCMESISA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=CN(C(=NC1=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-4-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H16N3O14P3/c10-9-11-5(13)1-2-12(9)8-7(15)6(14)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,14-15H,3H2,(H,19,20)(H,21,22)(H2,10,11,13)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

Synonyms: 4(1H)-Pyrimidinone, 2-amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-; 2-Amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-4(1H)-pyrimidinone; ((2R,3S,4R,5R)-5-(2-amino-4-oxopyrimidin-1(4H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; isoCTP

Guanosine-5'-O-(2-thiodiphosphate)

Description: GDP-βS is guanosine 5'-O-(2-thiodiphosphate), a modified form of guanosine diphosphate (GDP) where the oxygen in the β-phosphate position is replaced by a sulfur atom. It is commonly used as a non-hydrolyzable analog of GDP in biochemical studies to investigate GTPase activity, signal transduction pathways, and molecular mechanisms involving GTP-binding proteins (G proteins).

CAT: BRP-01645

CAS: 71376-97-1

Molecular Formula: C10H15N5O10P2S

Molecular Weight: 459.27

Purity: ≥90% by HPLC

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

Density: 2.55±0.1 g/cm3

Boiling Point: 901.1±75.0 °C at 760 mmHg

InChIKey: QJXJXBXFIOTYHB-UUOKFMHZSA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=S)(O)O)O)O)N=C(NC2=O)N

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydroxyphosphinothioyl hydrogen phosphate

InChI: InChI=1S/C10H15N5O10P2S/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(24-9)1-23-26(19,20)25-27(21,22)28/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H2,21,22,28)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1

Synonyms: 5'-Guanylic acid, anhydride with phosphorothioic acid (1:1); 5'-Guanylic acid, monoanhydride with phosphorothioic acid; GDP-βS; Guanosine 5'-(β-thiodiphosphate); Guanosine 5'-O-(2-thiodiphosphate); Guanosine 5'-O-(β-thiodiphosphate); Guanyl-5'-yl thiophosphate

Related CAS: 97952-36-8 (trilithium salt) ; 2179317-10-1 (x-ammonium salt) ; 906735-10-2 (triethylamine salt (1:x)) ; 948028-69-1 (triethylamine salt (1:1)) ; 1397700-13-8 (triethylamine salt (1:3))

7-Methyl-guanosine-5'-monophosphate, triethylamine salt

Description: 7-Methyl-guanosine-5'-monophosphate, triethylamine salt, is a nucleotide where 7-methyl-guanosine, a modified nucleoside, is phosphorylated at the 5' position and combined with triethylamine to form its salt. 7-Methyl-guanosine-5'-monophosphate, triethylamine salt, can be used in research involving RNA capping mechanisms, RNA modification and structure, RNA-protein interactions, and the role of modified nucleosides in RNA stability and function. It is also useful in studies aiming to understand the biochemistry of RNA and its various modifications.

CAT: BRP-01646

Molecular Formula: C11H16N5O8P (free acid)

Molecular Weight: 377.25 (free acid)

Purity: ≥95% by HPLC

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IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate;N,N-diethylethanamine

Synonyms: N1-methyl-guanosine-5'-monophosphate, triethylamine salt; N7-Me-GMP TEA salt; N(7)-methylguanosine 5'-phosphate triethylamine salt; 7-Methyl-5'-guanylic acid inner salt, triethylamine salt; 2-Amino-1,6-dihydro-7-methyl-6-oxo-9-beta-D-ribofuranosylpurinium hydroxide, 5'-phosphate, inner salt, triethylamine salt; 7-Methylguanosine-5'-monophosphate, triethylamine salt

Related CAS: 10162-58-0 (free base)

5-Methylcytidine-5'-monophosphate

Description: 5-methylcytidine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate having 5-methylcytosine as the nucleobase. It derives from a cytidine 5'-monophosphate.

CAT: BRP-01647

CAS: 3590-36-1

Molecular Formula: C10H16N3O8P

Molecular Weight: 337.22

Purity: ≥95% by HPLC

Appearance: White to Off-white Powder

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Storage: Store at -20°C

Density: 2.04±0.1 g/cm3

Boiling Point: 666.5±65.0°C at 760 mmHg

InChIKey: NJQONZSFUKNYOY-JXOAFFINSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C10H16N3O8P/c1-4-2-13(10(16)12-8(4)11)9-7(15)6(14)5(21-9)3-20-22(17,18)19/h2,5-7,9,14-15H,3H2,1H3,(H2,11,12,16)(H2,17,18,19)/t5-,6-,7-,9-/m1/s1

Synonyms: 5-Methyl-cytidine-5'-monophosphate, free acid; 5-Me-CMP.H2; 5-Me-CMP; 5-Methyl-CMP; m5CMP; 5-Methylcytidylic acid; 5-methylcytidine 5'-(dihydrogen phosphate); ((2R,3S,4R,5R)-5-(4-Amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate; Cytidine, 5-methyl-, 5'-(dihydrogen phosphate)

Related CAS: 117309-80-5 (ammonium salt)

6-Chloroinosine monophosphate

Description: 6-Chloroinosine monophosphate is a derivative of inosine monophosphate (IMP) where a chlorine atom is substituted at the 6th position of the purine ring. This modified nucleotide analog is utilized in biochemical and molecular biology research for probing nucleic acid structure, enzymatic reactions, and as a substrate for various enzymes. It can also serve as a precursor for the synthesis of modified nucleic acids for studying structure-function relationships or for therapeutic applications.

CAT: BRP-01648

CAS: 5843-59-4

Molecular Formula: C10H12ClN4O7P

Molecular Weight: 366.65

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InChIKey: ALOBOMYIOYNCBS-KQYNXXCUSA-N

CanonicalSMILES: C1=NC2=C(C(=N1)Cl)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(6-chloropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C10H12ClN4O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

Synonyms: 6-Cl-adenosine-5'-monophosphate; 6-Cl-AMP; 6-Cl-Purine Ribotide; 6-Chloropurine riboside 5'-monophosphate; 6-Chloropurine ribotide; 6-Chloropurine riboside 5'-phosphate; 6-Chloropurine 9-beta-D-ribofuranosyl 5'-monophosphate; 6-Chloro-9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purine; ((2R,3S,4R,5R)-5-(6-Chloro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate

2'-O-Methylguanosine 5'-monophosphate

Description: 2'-O-Methylguanosine 5'-monophosphate triethylammonium salt is a critical compound extensively used in the biomedical industry. It plays a crucial role in the treatment and research of various diseases, including viral infections, cancer, and neurological disorders. This product contributes to the development of targeted therapies and is an essential component in nucleic acid-based drug formulations. Its high purity and quality make it a valuable tool for biomedical research and drug discovery.

CAT: BRP-01650

CAS: 24121-01-5

Molecular Formula: C11H16N5O8P

Molecular Weight: 377.25

Purity: ≥95% by HPLC

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Storage: Store at 2-8 °C, Keep in a dark and dry place

Density: 2.20±0.10 g/cm3

InChIKey: YPMKZCOIEXUDSS-KQYNXXCUSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=O)(O)O)O

IUPAC Name: [(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C11H16N5O8P/c1-22-7-6(17)4(2-23-25(19,20)21)24-10(7)16-3-13-5-8(16)14-11(12)15-9(5)18/h3-4,6-7,10,17H,2H2,1H3,(H2,19,20,21)(H3,12,14,15,18)/t4-,6-,7-,10-/m1/s1

Synonyms: 2'-O-Methyl-5'-guanylic acid; 2'-O-Mgmp; 2'-O-Methyl-guanosine 5'-monophosphate; 2'-O-Me-GMP; 2'-O-Methylguanosine 5'-(dihydrogen phosphate)

Related CAS: 28998-31-4 (monoammonium salt) ; 666720-92-9 (TEA salt)

UTPγS

Description: UTPγS is a nucleotide analog widely used in biomedical research. It serves as a substrate for enzymes involved in RNA synthesis and modification. UTPγS is employed in studies investigating RNA structure, RNA-protein interactions, and ribozyme activities. It finds applications in the exploration of RNA-based therapeutics and drug development targeting infectious diseases.

CAT: BRP-01651

CAS: 79049-97-1

Molecular Formula: C9H15N2O14P3S

Molecular Weight: 500.20

Purity: ≥95% by HPLC

Appearance: solid

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Storage: Store at -20 °C

InChIKey: DUDALCZPYHIGIR-XVFCMESISA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=S)(O)O)O)O

IUPAC Name: dihydroxyphosphinothioyl [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate

InChI: InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(23-8)3-22-26(16,17)24-27(18,19)25-28(20,21)29/h1-2,4,6-8,13-14H,3H2,(H,16,17)(H,18,19)(H,10,12,15)(H2,20,21,29)/t4-,6-,7-,8-/m1/s1

Synonyms: Uridine-5'-(γ-thio)-triphosphate; Uridine-5'-O-(γ-Thio)-triphosphate; UTP-γS; Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid; UTP-Gamma-S; Uridine 5'-O-(3-thiotriphosphate)

Related CAS: 1266569-94-1 (trisodium salt)

Inosine 5'-monophosphate monopotassium salt

2'-F-m7GMP sodium salt

2'-F-m7GMP ammonium salt

2'-F-m7GMP TEA Salt

2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, ammonium salt

2'-Fluoro-2'-deoxyguanosine-5'-monophosphate, disodium salt

Iso-GTP

8-Oxo-GTP

2-Fluoro-ATP

Inosine 5'-(tetrahydrogen triphosphate)

5-Fluoro-UTP

5-Ethynyl-UTP

NHC-triphosphate

Isocytidine triphosphate

Guanosine-5'-O-(2-thiodiphosphate)

7-Methyl-guanosine-5'-monophosphate, triethylamine salt

5-Methylcytidine-5'-monophosphate

6-Chloroinosine monophosphate

2'-O-Methylguanosine 5'-monophosphate

UTPγS

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