Nucleotides - RNA / BOC Sciences

8-Oxo-GTP

Description: 8-Oxo-GTP, a nucleotide with modifications, is a valuable tool in discovering RNA oxidative and repair mechanisms. Its versatile use also includes investigations into Alzheimer's and Parkinson's, as well as cancer. Its potential to provide antioxidant properties demonstrates promise for defending against oxidative stress in various disease states.

CAT: BRP-01611

CAS: 21238-36-8

MF: C10H16N5O15P3

MF: 539.18

Purity: ≥95% by HPLC

Appearance: Lyophilized white powder

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Storage: Store at -20 °C

Density: 2.88±0.1 g/cm3

InChIKey: JCHLKIQZUXYLPW-UMMCILCDSA-N

Solubility: Soluble in Water

CanonicalSMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)NC2=O)O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-6,8-dioxo-1,7-dihydropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H16N5O15P3/c11-9-13-6-3(7(18)14-9)12-10(19)15(6)8-5(17)4(16)2(28-8)1-27-32(23,24)30-33(25,26)29-31(20,21)22/h2,4-5,8,16-17H,1H2,(H,12,19)(H,23,24)(H,25,26)(H2,20,21,22)(H3,11,13,14,18)/t2-,4-,5-,8-/m1/s1

Synonyms: 8-Oxoguanosine-5'-Triphosphate; 7,8-Dihydro-8-oxoguanosine 5'-(tetrahydrogen triphosphate); Purine-6,8(1H,9H)-dione, 2-amino-9-β-D-ribofuranosyl-, 5'-(tetrahydrogen triphosphate); 8-Ketoguanosine 5'-triphosphate

2-Fluoro-ATP

Description: 2-Fluoro-ATP is a toxic metabolite of 9-β-D-arabinosyl-2-fluoroadenine, an anticancer drug. 2-Fluoro-ATP is commonly used as a versatile tool for 19F NMR-based activity screening.

CAT: BRP-01612

CAS: 1492-62-2

MF: C10H15FN5O13P3

MF: 525.17

Purity: ≥95% by HPLC

Appearance: Lyophilized white powder

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Storage: Store at -20 °C

Density: 2.68±0.1 g/cm3

Boiling Point: 1006.2±75.0 °C at 760 mmHg

InChIKey: PIOKUWLZUXUBCO-UUOKFMHZSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)F)N

IUPAC Name: [[(2R,3S,4R,5R)-5-(6-amino-2-fluoropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: 1S/C10H15FN5O13P3/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,17-18H,1H2,(H,22,23)(H,24,25)(H2,12,14,15)(H2,19,20,21)/t3-,5-,6-,9-/m1/s1

Synonyms: (2F-ATP); 2-Fluoro-adenosine-5'-triphosphate; 2-F-ATP; 2-Fluoroadenosine 5'-(tetrahydrogen triphosphate); Adenosine, 2-fluoro-, 5'-(tetrahydrogen triphosphate); Adenosine, 2-fluoro-, 5'-triphosphate; 2-Fluoroadenine-9β-D-ribofuranoside 5'-triphosphate; 2-Fluoroadenosine 5'-triphosphate; 2-Fluoroadenosine triphosphate

Inosine 5'-(tetrahydrogen triphosphate)

Description: Inosine 5'-(tetrahydrogen triphosphate) is a bioactive organic molecule with immense therapeutic potential in addressing an array of ailments- from cancer, metabolic afflictions, to viral infections. It functions as an indispensable precursor for purine nucleotide synthesis, thereby stimulating ATP production, augmenting cellular energy reserves, and activating immune cells such as T-cells to ramp up response to various intruders.

CAT: BRP-01613

CAS: 132-06-9

MF: C10H15N4O14P3

MF: 508.17

Purity: ≥98% by AX-HPLC

Appearance: Lyophilized white powder

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Storage: Store at -20 °C

Density: 2.63 g/cm3

InChIKey: HAEJPQIATWHALX-KQYNXXCUSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H15N4O14P3/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

Synonyms: ITP; Hypoxanthine; Inosine-5'-Triphosphate; Inosine 5'-(tetrahydrogen triphosphate); 5'-ITP; Inosine 5'-triphosphate; Inosine triphosphate

Related CAS: 35908-31-7 (trisodium salt) ; 14356-95-7 (tetrasodium salt)

5-Fluoro-UTP

Description: 5-Fluoro-UTP is an DNA/RNA synthesis inhibitor that terminate synthesis of nucleotide through inhibiting thymidylate synthase. It is used as an anticancer drug.

CAT: BRP-01614

CAS: 3828-96-4

MF: C9H14FN2O15P3

MF: 502.13

Purity: ≥95% by HPLC

Appearance: Lyophilized white powder

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Storage: Store at -20 °C

Density: 2.13±0.1 g/cm3

Application: 5-Fluoro-UTP is an DNA/RNA synthesis inhibitor.

InChIKey: AREUQFTVCMGENT-UAKXSSHOSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)F

IUPAC Name: [[(2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H14FN2O15P3/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(25-8)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1

Synonyms: (5F-UTP); 5-Fluoro-uridine-5'-triphosphate; 5-F-UTP; 5-Fluorouridine 5'-(tetrahydrogen triphosphate); Uridine, 5-fluoro-, 5'-(tetrahydrogen triphosphate); Uridine, 5-fluoro-, 5'-triphosphate; 5-Fluorouridine 5'-triphosphate; 5-Fluorouridine triphosphate; Fluorouridine triphosphate

5-Ethynyl-UTP

Description: 5-Ethynyl-UTP is a compound acting as a ubiquitous substrate to foster DNA research and development and modification.

CAT: BRP-01615

CAS: 1004955-96-7

MF: C11H15N2O15P3

MF: 508.16

Purity: ≥95% by HPLC

Appearance: Lyophilized white powder

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Storage: Store at -20°C

Density: 2.05±0.1 g/cm3

InChIKey: AGTYLGHUHWJTSE-FDDDBJFASA-N

Solubility: Soluble in Water

CanonicalSMILES: C#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(5-ethynyl-2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C11H15N2O15P3/c1-2-5-3-13(11(17)12-9(5)16)10-8(15)7(14)6(26-10)4-25-30(21,22)28-31(23,24)27-29(18,19)20/h1,3,6-8,10,14-15H,4H2,(H,21,22)(H,23,24)(H,12,16,17)(H2,18,19,20)/t6-,7-,8-,10-/m1/s1

Synonyms: 5-Ethynyluridine 5'-(tetrahydrogen triphosphate); 5-Ethynyl-deoxyuridine triphosphate; 5-Ethynyl uridine-triphosphate

NHC-triphosphate

Description: N 4-Hydroxycytidine (NHC) is an antiviral ribonucleoside analog that acts as a competitive alternative substrate for virally encoded RNA-dependent RNA polymerases. NHC-triphosphate is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA.

CAT: BRP-01616

CAS: 34973-27-8

MF: C9H16N3O15P3

MF: 499.16

Purity: 98%

Appearance: White or off-white solid

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Storage: Store at -20°C

Density: 2.52±0.1 g/cm3

InChIKey: BNIQIYMICUFERK-XVFCMESISA-N

Solubility: Soluble in DMSO

CanonicalSMILES: C1=CN(C(=O)N=C1NO)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H16N3O15P3/c13-6-4(3-24-29(20,21)27-30(22,23)26-28(17,18)19)25-8(7(6)14)12-2-1-5(11-16)10-9(12)15/h1-2,4,6-8,13-14,16H,3H2,(H,20,21)(H,22,23)(H,10,11,15)(H2,17,18,19)/t4-,6-,7-,8-/m1/s1

Synonyms: N4-Hydroxycytidine 5'-triphosphate; N4-hydroxy-CTP; Uridine 5'-(tetrahydrogen triphosphate), 4-oxime; Uridine, 4-oxime, 5'-triphosphate; 1-β-D-Ribofuranosyl-4-hydroxylamino-2-pyrimidinone 5'-triphosphate; EIDD 2061; EIDD-1931 triphosphate; N4-Hydroxycytidine triphosphate

Isocytidine triphosphate

Description: Isocytidine Triphosphate is an essential biochemical compound for disease research and nucleotide metabolism studies, serving as an indispensable precursor for synthesizing nucleotides bustling with isocytidine. Embedded within the intricate tapestry of DNA and RNA metabolism, these nucleotides emerge as cornerstones, intricately involved in studying viral infections and navigating genetic disorders.

CAT: BRP-01618

CAS: 150668-55-6

MF: C9H16N3O14P3

MF: 483.16

Purity: >95%

Appearance: Lyophilized white powder

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Storage: Store at -20 °C

Density: 2.50±0.1 g/cm3

Boiling Point: 849.2±75.0°C at 760 mmHg

InChIKey: MIJSFJCPGQQTMK-XVFCMESISA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=CN(C(=NC1=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-4-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C9H16N3O14P3/c10-9-11-5(13)1-2-12(9)8-7(15)6(14)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,14-15H,3H2,(H,19,20)(H,21,22)(H2,10,11,13)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

Synonyms: 4(1H)-Pyrimidinone, 2-amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-; 2-Amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-4(1H)-pyrimidinone; ((2R,3S,4R,5R)-5-(2-amino-4-oxopyrimidin-1(4H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; isoCTP

Guanosine-5'-O-(2-thiodiphosphate)

Description: GDP-βS is guanosine 5'-O-(2-thiodiphosphate), a modified form of guanosine diphosphate (GDP) where the oxygen in the β-phosphate position is replaced by a sulfur atom. It is commonly used as a non-hydrolyzable analog of GDP in biochemical studies to investigate GTPase activity, signal transduction pathways, and molecular mechanisms involving GTP-binding proteins (G proteins).

CAT: BRP-01645

CAS: 71376-97-1

MF: C10H15N5O10P2S

MF: 459.27

Purity: ≥90% by HPLC

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Storage: Store at -20 °C, Always avoid freeze-thaw cycles

Density: 2.55±0.1 g/cm3

Boiling Point: 901.1±75.0 °C at 760 mmHg

InChIKey: QJXJXBXFIOTYHB-UUOKFMHZSA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=S)(O)O)O)O)N=C(NC2=O)N

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydroxyphosphinothioyl hydrogen phosphate

InChI: InChI=1S/C10H15N5O10P2S/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(24-9)1-23-26(19,20)25-27(21,22)28/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H2,21,22,28)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1

Synonyms: 5'-Guanylic acid, anhydride with phosphorothioic acid (1:1); 5'-Guanylic acid, monoanhydride with phosphorothioic acid; GDP-βS; Guanosine 5'-(β-thiodiphosphate); Guanosine 5'-O-(2-thiodiphosphate); Guanosine 5'-O-(β-thiodiphosphate); Guanyl-5'-yl thiophosphate

Related CAS: 97952-36-8 (trilithium salt) ; 2179317-10-1 (x-ammonium salt) ; 906735-10-2 (triethylamine salt (1:x)) ; 948028-69-1 (triethylamine salt (1:1)) ; 1397700-13-8 (triethylamine salt (1:3))

7-Methyl-guanosine-5'-monophosphate, triethylamine salt

Description: 7-Methyl-guanosine-5'-monophosphate, triethylamine salt, is a nucleotide where 7-methyl-guanosine, a modified nucleoside, is phosphorylated at the 5' position and combined with triethylamine to form its salt. 7-Methyl-guanosine-5'-monophosphate, triethylamine salt, can be used in research involving RNA capping mechanisms, RNA modification and structure, RNA-protein interactions, and the role of modified nucleosides in RNA stability and function. It is also useful in studies aiming to understand the biochemistry of RNA and its various modifications.

CAT: BRP-01646

MF: C11H16N5O8P (free acid)

MF: 377.25 (free acid)

Purity: ≥95% by HPLC

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IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate;N,N-diethylethanamine

Synonyms: N1-methyl-guanosine-5'-monophosphate, triethylamine salt; N7-Me-GMP TEA salt; N(7)-methylguanosine 5'-phosphate triethylamine salt; 7-Methyl-5'-guanylic acid inner salt, triethylamine salt; 2-Amino-1,6-dihydro-7-methyl-6-oxo-9-beta-D-ribofuranosylpurinium hydroxide, 5'-phosphate, inner salt, triethylamine salt; 7-Methylguanosine-5'-monophosphate, triethylamine salt

Related CAS: 10162-58-0 (free base)

5-Methylcytidine-5'-monophosphate

Description: 5-methylcytidine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate having 5-methylcytosine as the nucleobase. It derives from a cytidine 5'-monophosphate.

CAT: BRP-01647

CAS: 3590-36-1

MF: C10H16N3O8P

MF: 337.22

Purity: ≥95% by HPLC

Appearance: White to Off-white Powder

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Storage: Store at -20°C

Density: 2.04±0.1 g/cm3

Boiling Point: 666.5±65.0°C at 760 mmHg

InChIKey: NJQONZSFUKNYOY-JXOAFFINSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C10H16N3O8P/c1-4-2-13(10(16)12-8(4)11)9-7(15)6(14)5(21-9)3-20-22(17,18)19/h2,5-7,9,14-15H,3H2,1H3,(H2,11,12,16)(H2,17,18,19)/t5-,6-,7-,9-/m1/s1

Synonyms: 5-Methyl-cytidine-5'-monophosphate, free acid; 5-Me-CMP.H2; 5-Me-CMP; 5-Methyl-CMP; m5CMP; 5-Methylcytidylic acid; 5-methylcytidine 5'-(dihydrogen phosphate); ((2R,3S,4R,5R)-5-(4-Amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate; Cytidine, 5-methyl-, 5'-(dihydrogen phosphate)

Related CAS: 117309-80-5 (ammonium salt)

6-Chloroinosine monophosphate

Description: 6-Chloroinosine monophosphate is a derivative of inosine monophosphate (IMP) where a chlorine atom is substituted at the 6th position of the purine ring. This modified nucleotide analog is utilized in biochemical and molecular biology research for probing nucleic acid structure, enzymatic reactions, and as a substrate for various enzymes. It can also serve as a precursor for the synthesis of modified nucleic acids for studying structure-function relationships or for therapeutic applications.

CAT: BRP-01648

CAS: 5843-59-4

MF: C10H12ClN4O7P

MF: 366.65

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InChIKey: ALOBOMYIOYNCBS-KQYNXXCUSA-N

CanonicalSMILES: C1=NC2=C(C(=N1)Cl)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(6-chloropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C10H12ClN4O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

Synonyms: 6-Cl-adenosine-5'-monophosphate; 6-Cl-AMP; 6-Cl-Purine Ribotide; 6-Chloropurine riboside 5'-monophosphate; 6-Chloropurine ribotide; 6-Chloropurine riboside 5'-phosphate; 6-Chloropurine 9-beta-D-ribofuranosyl 5'-monophosphate; 6-Chloro-9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purine; ((2R,3S,4R,5R)-5-(6-Chloro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate

8-Bromo-cAMP sodium salt

Description: 8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA. It inhibits cell growth, decreases proliferation, increases differentiation and induces apoptosis.

CAT: BRP-01649

CAS: 76939-46-3

MF: C10H10BrN5NaO6P

MF: 430.08

Purity: ≥95% by HPLC

Appearance: Off-white powder

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Storage: Store at -20 °C

Shelf Life: 2 years if stored properly

InChIKey: DMRMZQATXPQOTP-GWTDSMLYSA-M

Solubility: Soluble in DMSO, Ethanol, Water

CanonicalSMILES: C1C2C(C(C(O2)N3C4=NC=NC(=C4N=C3Br)N)O)OP(=O)(O1)[O-].[Na+]

IUPAC Name: sodium;(4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol

InChI: InChI=1S/C10H11BrN5O6P.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

Synonyms: 8-Br-3',5'-cyclo-adenosine monophosphate, sodium salt; 8-Br-3',5'-cyclo-AMP.Na; (8Br-cAMP) sodium salt; 8-Bromo-adenosine-3',5'-cyclic monophosphate, Sodium salt; 8-Br-cAMP sodium salt; 8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt; Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate), sodium salt (1:1)

Related CAS: 23583-48-4 (free acid)

2'-O-Methylguanosine 5'-monophosphate

Description: 2'-O-Methylguanosine 5'-monophosphate triethylammonium salt is a critical compound extensively used in the biomedical industry. It plays a crucial role in the treatment and research of various diseases, including viral infections, cancer, and neurological disorders. This product contributes to the development of targeted therapies and is an essential component in nucleic acid-based drug formulations. Its high purity and quality make it a valuable tool for biomedical research and drug discovery.

CAT: BRP-01650

CAS: 24121-01-5

MF: C11H16N5O8P

MF: 377.25

Purity: ≥95% by HPLC

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Storage: Store at 2-8 °C, Keep in a dark and dry place

Density: 2.20±0.10 g/cm3

InChIKey: YPMKZCOIEXUDSS-KQYNXXCUSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=O)(O)O)O

IUPAC Name: [(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methyl dihydrogen phosphate

InChI: InChI=1S/C11H16N5O8P/c1-22-7-6(17)4(2-23-25(19,20)21)24-10(7)16-3-13-5-8(16)14-11(12)15-9(5)18/h3-4,6-7,10,17H,2H2,1H3,(H2,19,20,21)(H3,12,14,15,18)/t4-,6-,7-,10-/m1/s1

Synonyms: 2'-O-Methyl-5'-guanylic acid; 2'-O-Mgmp; 2'-O-Methyl-guanosine 5'-monophosphate; 2'-O-Me-GMP; 2'-O-Methylguanosine 5'-(dihydrogen phosphate)

Related CAS: 28998-31-4 (monoammonium salt) ; 666720-92-9 (TEA salt)

UTPγS

Description: UTPγS is a nucleotide analog widely used in biomedical research. It serves as a substrate for enzymes involved in RNA synthesis and modification. UTPγS is employed in studies investigating RNA structure, RNA-protein interactions, and ribozyme activities. It finds applications in the exploration of RNA-based therapeutics and drug development targeting infectious diseases.

CAT: BRP-01651

CAS: 79049-97-1

MF: C9H15N2O14P3S

MF: 500.20

Purity: ≥95% by HPLC

Appearance: solid

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Storage: Store at -20 °C

InChIKey: DUDALCZPYHIGIR-XVFCMESISA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=S)(O)O)O)O

IUPAC Name: dihydroxyphosphinothioyl [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate

InChI: InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(23-8)3-22-26(16,17)24-27(18,19)25-28(20,21)29/h1-2,4,6-8,13-14H,3H2,(H,16,17)(H,18,19)(H,10,12,15)(H2,20,21,29)/t4-,6-,7-,8-/m1/s1

Synonyms: Uridine-5'-(γ-thio)-triphosphate; Uridine-5'-O-(γ-Thio)-triphosphate; UTP-γS; Uridine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid; UTP-Gamma-S; Uridine 5'-O-(3-thiotriphosphate)

Related CAS: 1266569-94-1 (trisodium salt)

UTPγS trisodium salt

Description: UTPγS trisodium salt is a selective P2Y2 and P2Y4 receptor agonist.

CAT: BRP-01652

CAS: 1266569-94-1

MF: C9H12N2Na3O14P3S

MF: 566.15

Purity: ≥95% by HPLC

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InChIKey: DBXMFBSCFRDIOA-LLWADOMFSA-K

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=S)(O)[O-])O)O.[Na+].[Na+].[Na+]

IUPAC Name: trisodium;[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [hydroxy(oxido)phosphinothioyl] phosphate

InChI: InChI=1S/C9H15N2O14P3S.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(23-8)3-22-26(16,17)24-27(18,19)25-28(20,21)29;;;/h1-2,4,6-8,13-14H,3H2,(H,16,17)(H,18,19)(H,10,12,15)(H2,20,21,29);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1

Synonyms: Trisodium ({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)({[hydroxy(oxido)sulfanylidene-|E-phosphanyl]oxy})phosphinate; Uridine-5'-(γ-thio)-triphosphate trisodium salt; UTP-γS trisodium salt; Uridine 5'-O-(3-thiotriphosphate) trisodium salt

Related CAS: 79049-97-1 (free acid)

2'-O-Methylguanosine-5'-triphosphate trilithium salt

Description: 2'-O-Methylguanosine-5'-triphosphate trilithium salt, a highly versatile compound, can be employed as an efficient probe for investigating RNA metabolism. It possesses the remarkable capability of obstructing RNA chain elongation, thus making it an invaluable research tool in the field. In addition to its chain terminating property, it also exhibits remarkable affinity with RNA-binding proteins and catalytic ribozymes, rendering it ideal for studying complex RNA-protein interactions and enzymatic activities.

CAT: BRP-01653

MF: C11H15Li3N5O14P3

MF: 555.00

Purity: ≥97% by HPLC

Appearance: Clear colorless liquid

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InChIKey: DNABKBYLELJGQR-MSQVLRTGSA-K

CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O

IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C11H18N5O14P3.3Li/c1-26-7-6(17)4(2-27-32(22,23)30-33(24,25)29-31(19,20)21)28-10(7)16-3-13-5-8(16)14-11(12)15-9(5)18;;;/h3-4,6-7,10,17H,2H2,1H3,(H,22,23)(H,24,25)(H2,19,20,21)(H3,12,14,15,18);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1

Synonyms: 2'-O-Me-GTP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methylguanosine; Guanosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate

Related CAS: 61556-44-3 (free acid)

2'-O-Methyladenosine-5'-triphosphate trilithium salt

Description: 2'-O-Methyladenosine-5'-triphosphate trilithium salt, a prominent nucleotide analog in enzymatic assays detecting ATP-utilizing proteins, and in RNA structure/function studies, specific to RNA modification and translation analysis, showcases its multifarious and intriguing features. Its utilization in diverse experimental applications underlines its enormous potential and capacity to facilitate cutting-edge researches in biomedical and pharmaceutical sciences.

CAT: BRP-01654

MF: C11H15Li3N5O13P3

MF: 539.00

Purity: ≥97% by HPLC

Appearance: Clear colorless liquid

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InChIKey: QIQIMTPLFXIYPZ-MTQUBGKESA-K

CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=NC3=C(N=CN=C32)N)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O

IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C11H18N5O13P3.3Li/c1-25-8-7(17)5(2-26-31(21,22)29-32(23,24)28-30(18,19)20)27-11(8)16-4-15-6-9(12)13-3-14-10(6)16;;;/h3-5,7-8,11,17H,2H2,1H3,(H,21,22)(H,23,24)(H2,12,13,14)(H2,18,19,20);;;/q;3*+1/p-3/t5-,7-,8-,11-;;;/m1.../s1

Synonyms: 2'-O-methyl-adenosine-5'-triphosphate, lithium salt; 2'-O-Me-ATP Lithium Salt; lithium ((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 2'-O-Me-ATP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methyladenosine; Adenosine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3)

Related CAS: 30948-06-2 (free acid) ; 100020-58-4 (tetrasodium salt)

2'-O-Methylcytidine-5'-triphosphate trilithium salt

Description: 2'-O-Methylcytidine-5'-triphosphate trilithium salt, a nucleotide derivative employed frequently in RNA biosynthesis and modification investigations, holds immense promise in cancer therapies, especially as a competitive inhibitor of RNA polymerase II elongation. Compelling evidence also demonstrates its success as an inhibitor of viral replication, particularly in the context of hepatitis C.

CAT: BRP-01655

MF: C10H15Li3N3O14P3

MF: 514.98

Purity: ≥97% by HPLC

Appearance: Clear colorless liquid

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InChIKey: RIFSDAPMKYBRDH-WKMNQBAXSA-K

CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=CC(=NC2=O)N)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O

IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H18N3O14P3.3Li/c1-23-8-7(14)5(25-9(8)13-3-2-6(11)12-10(13)15)4-24-29(19,20)27-30(21,22)26-28(16,17)18;;;/h2-3,5,7-9,14H,4H2,1H3,(H,19,20)(H,21,22)(H2,11,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t5-,7-,8-,9-;;;/m1.../s1

Synonyms: 2'-O-methyl-cytidine-5'-triphosphate, lithium salt; 2'-O-Me-CTP Lithium Salt; 2'-O-Me-CTP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methylcytidine; Cytidine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); lithium ((2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 2'-O-methyl-Cytidine-5'-triphosphate, trilithium salt

Related CAS: 143028-98-2 (free acid)

2'-O-Methyluridine-5'-triphosphate trilithium salt

Description: 2'-O-Methyluridine-5'-triphosphate trilithium salt, a biochemical reagent widely applied in biomedicine to investigate RNA transcription and modification, is a valuable research tool with incomparable properties that afford an accurate insight of cellular processes related to RNA function and modification. Scientists favor its use as a substrate for RNA polymerase, that enables them to scrutinize RNA synthesis and modification of transcripts. Furthermore, this trilithium salt is constructive in analyzing RNA-protein interactions and probing ribozymes.

CAT: BRP-01656

MF: C10H14Li3N2O15P3

MF: 515.96

Purity: ≥97% by HPLC

Appearance: Clear colorless liquid

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InChIKey: ZBEHXEVNNHLIAB-WKMNQBAXSA-K

CanonicalSMILES: [Li+].[Li+].[Li+].COC1C(C(OC1N2C=CC(=O)NC2=O)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O

IUPAC Name: trilithium;[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H17N2O15P3.3Li/c1-23-8-7(14)5(25-9(8)12-3-2-6(13)11-10(12)15)4-24-29(19,20)27-30(21,22)26-28(16,17)18;;;/h2-3,5,7-9,14H,4H2,1H3,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18);;;/q;3*+1/p-3/t5-,7-,8-,9-;;;/m1.../s1

Synonyms: 2'-O-Methyl-uridine-5'-triphosphate, lithium salt; 2'-O-Me-UTP Lithium Salt; lithium ((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 2'-OMe-UTP trilithium salt; Trilithium 5'-O-[({[(hydroxyphosphinato)oxy]phosphinato}oxy)phosphinato]-2'-O-methyluridine; Uridine, 2'-O-methyl-, 5'-(tetrahydrogen triphosphate), lithium salt (1:3); 2'-methoxy-UTP trilithium salt; 2'-O-methyl-Uridine-5'-triphosphate, trilithium salt; 2'-OMe-UTP.Li3

Related CAS: 143028-99-3 (free acid)

2'-O-Methyluridine-5'-triphosphate

Description: 2'-O-Methyluridine-5'-triphosphate is a nucleotide analog commonly used in biochemistry research. It can be used as a substrate for RNA polymerases or as a terminoligical ATP analog for use in RNA synthesis reactions. Its effectiveness as an antiviral and antitumor agent is also being investigated.

CAT: BRP-01657

CAS: 143028-99-3

MF: C10H17N2O15P3

MF: 498.17

Purity: ≥97% by HPLC

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Density: 2.0±0.1 g/cm3

InChIKey: BQJWHJWAEOHVCK-ZOQUXTDFSA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O

IUPAC Name: [[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H17N2O15P3/c1-23-8-7(14)5(25-9(8)12-3-2-6(13)11-10(12)15)4-24-29(19,20)27-30(21,22)26-28(16,17)18/h2-3,5,7-9,14H,4H2,1H3,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18)/t5-,7-,8-,9-/m1/s1

Synonyms: 2'-methoxy-UTP; 2'-O-Methyluridine 5'-triphosphoric acid; uridine 5'-(tetrahydrogen triphosphate), 2'-O-methyl-; 5'-(tetrahydrogen triphosphate), 2'-O-methyl-Uridine; 2'-O-Methyluridine 5'-(tetrahydrogen triphosphate); 2'-O-Me-UTP; 2'-OMe-UTP