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2'-Modified Nucleotides
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2'-O-Methyl-GTP-βS
Description: 2'-O-Methyl-GTP-βS is a modified nucleotide compound used in biochemical research. It consists of a guanosine base with a methyl group at the 2'-position, linked to a guanosine triphosphate (GTP) moiety, and containing a sulfur (S) atom at the β position. This modification alters the reactivity of the nucleotide. It is frequently employed as a substrate analog in enzymatic assays and studies related to RNA modification, structural analysis, and RNA-protein interactions.
CAT: BRP-00790
MF: C11H18N5O13P3S
MF: 553.28
Purity: ≥98%
Appearance: Colorless transparent liquid
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|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C, Always avoid freeze-thaw cycles
Density: 2.45±0.1 g/cm3
Boiling Point: 931.1±75.0 °C at 760 mmHg
InChIKey: VJCFJRASRRBLIU-NRSRKINISA-N
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=O)(O)OP(=S)(O)OP(=O)(O)O)O
IUPAC Name: [(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methyl [hydroxy(phosphonooxy)phosphinothioyl] hydrogen phosphate
InChI: InChI=1S/C11H18N5O13P3S/c1-25-7-6(17)4(2-26-31(22,23)29-32(24,33)28-30(19,20)21)27-10(7)16-3-13-5-8(16)14-11(12)15-9(5)18/h3-4,6-7,10,17H,2H2,1H3,(H,22,23)(H,24,33)(H2,19,20,21)(H3,12,14,15,18)/t4-,6-,7-,10-,32?/m1/s1
Synonyms: β-Thio-((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl triphosphate; 2'-O-Methyl-GTPβS
α-Thio-pseudouridine-5'-triphosphate, trisodium salt
Description: α-Thio-pseudouridine-5'-triphosphate, trisodium salt is a modified nucleotide compound used in biochemical research. It contains a thio-modified pseudouridine base linked to a triphosphate group at the 5' carbon of the ribose sugar. This modification introduces a sulfur (S) atom at the α position of the pseudouridine. It is in the form of a trisodium salt. This compound is commonly utilized as a substrate analog in enzymatic assays and studies related to RNA modification, RNA structure-function relationships, and RNA-protein interactions.
CAT: BRP-00791
MF: C9H12N2Na3O14P3S
MF: 566.15
Purity: ≥98%
Appearance: Colorless transparent liquid
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| -- | -- | -- |
Storage: Store at -20 °C, Always avoid freeze-thaw cycles
InChIKey: MMSUJHCLVGJXAW-XMRXGGJWSA-K
CanonicalSMILES: C1=C(C(=O)NC(=O)N1)C2C(C(C(O2)COP(=S)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]
IUPAC Name: trisodium;[[[(2R,3S,4R,5S)-5-(2,4-dioxo-1H-pyrimidin-5-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphinothioyl]oxy-oxidophosphoryl] hydrogen phosphate
InChI: InChI=1S/C9H15N2O14P3S.3Na/c12-5-4(2-22-28(21,29)25-27(19,20)24-26(16,17)18)23-7(6(5)13)3-1-10-9(15)11-8(3)14;;;/h1,4-7,12-13H,2H2,(H,19,20)(H,21,29)(H2,16,17,18)(H2,10,11,14,15);;;/q;3*+1/p-3/t4-,5-,6-,7+,28?;;;/m1.../s1
Synonyms: alpha-Thio-pseudouridine-5'-triphosphate, trisodium salt
5-Methyl-CTP-αS
Description: 5-Methyl-CTP-αS is a modified nucleotide compound used in biochemical research. It consists of a cytidine base with a methyl group at the 5th position, linked to a cytidine triphosphate (CTP) moiety, and containing a sulfur (S) atom at the α position. This modification alters the reactivity of the nucleotide. It is often utilized as a substrate analog in enzymatic assays and studies related to RNA modification, RNA labeling, and RNA-protein interactions.
CAT: BRP-00792
MF: C10H18N3O13P3S
MF: 513.25
Purity: ≥98%
Appearance: Colorless transparent liquid
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| -- | -- | -- |
Storage: Store at -20 °C, Always avoid freeze-thaw cycles
InChIKey: PQLJKNQISGQQDR-GWKANUBMSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=S)(O)OP(=O)(O)OP(=O)(O)O)O)O
IUPAC Name: [[(2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate
InChI: InChI=1S/C10H18N3O13P3S/c1-4-2-13(10(16)12-8(4)11)9-7(15)6(14)5(24-9)3-23-29(22,30)26-28(20,21)25-27(17,18)19/h2,5-7,9,14-15H,3H2,1H3,(H,20,21)(H,22,30)(H2,11,12,16)(H2,17,18,19)/t5-,6-,7-,9-,29?/m1/s1
Synonyms: α-Thio-((2R,3S,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate; 5-Methylcytidine, 5'→P''-ester with thiotriphosphoric acid; 5-Methylcytidine-5'-O-(1-thiotriphosphate); 5-Methyl-CTPαS
2'-O-Methyl-ATP-αS
Description: 2'-O-Methyl-ATP-αS is a modified nucleotide compound used in biochemical research. It consists of an adenosine base with a methyl group at the 2'-position, linked to an adenosine triphosphate (ATP) moiety, and containing a sulfur (S) atom at the α position. This modification alters the reactivity of the nucleotide. It is commonly employed as a substrate analog in enzymatic assays and studies related to RNA modification, RNA labeling, and RNA-protein interactions.
CAT: BRP-00793
CAS: 926631-26-7
MF: C11H18N5O12P3S
MF: 537.28
Purity: ≥98%
Appearance: Colorless transparent liquid
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|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C, Always avoid freeze-thaw cycles
Density: 2.35±0.1 g/cm3
Boiling Point: 864.5±75.0 °C at 760 mmHg
InChIKey: PPIGLURRZVMGQO-YOLSTXSHSA-N
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)N)COP(=S)(O)OP(=O)(O)OP(=O)(O)O)O
IUPAC Name: [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate
InChI: InChI=1S/C11H18N5O12P3S/c1-24-8-7(17)5(2-25-31(23,32)28-30(21,22)27-29(18,19)20)26-11(8)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17H,2H2,1H3,(H,21,22)(H,23,32)(H2,12,13,14)(H2,18,19,20)/t5-,7-,8-,11-,31?/m1/s1
Synonyms: α-Thio-((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl triphosphate; 2'-O-Methyladenosine-5'-O-(1-Thiotriphosphate); 2'-O-Methyl-ATP-α-S; 2'-O-Methyl-ATPαS; Adenosine, 2'-O-methyl-, 5'→P''-ester with thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(O)(OH)(SH))
2'-O-Methyl-GTP-αS
Description: 2'-O-Methyl-GTP-αS is a modified nucleotide compound used in biochemical research. It contains a guanosine base with a methyl group at the 2'-position, linked to a guanosine triphosphate (GTP) moiety, and containing a sulfur (S) atom at the α position. This modification alters the reactivity of the nucleotide. It is frequently used as a substrate analog in enzymatic assays and studies related to RNA modification, RNA labeling, and RNA-protein interactions.
CAT: BRP-00794
CAS: 847648-38-8
MF: C11H18N5O13P3S
MF: 553.28
Purity: ≥98%
Appearance: Colorless transparent liquid
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C, Always avoid freeze-thaw cycles
Density: 2.45±0.1 g/cm3
Boiling Point: 931.1±75.0 °C at 760 mmHg
InChIKey: PTDOTKSKFQMXQJ-NRSRKINISA-N
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=S)(O)OP(=O)(O)OP(=O)(O)O)O
IUPAC Name: [[(2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate
InChI: InChI=1S/C11H18N5O13P3S/c1-25-7-6(17)4(2-26-32(24,33)29-31(22,23)28-30(19,20)21)27-10(7)16-3-13-5-8(16)14-11(12)15-9(5)18/h3-4,6-7,10,17H,2H2,1H3,(H,22,23)(H,24,33)(H2,19,20,21)(H3,12,14,15,18)/t4-,6-,7-,10-,32?/m1/s1
Synonyms: α-Thio-((2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl triphosphate; Guanosine, 2'-O-methyl-, 5'→P''-ester with thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(O)(OH)(SH)); 2'-O-Methyl-GTPαS
5-Methoxyuridine 5'-monophosphate
Description: 5-Methoxyuridine 5'-monophosphate is a modified nucleotide used in biochemical research. It consists of a uridine base with a methoxy group at the 5th position and a monophosphate group attached to the 5' carbon of the ribose sugar. This compound is commonly employed in studies of RNA synthesis, modification, and function, helping to elucidate the roles of modified nucleotides in biological processes and potential therapeutic applications.
CAT: BRP-00806
CAS: 36908-07-3
MF: C10H15N2O10P
MF: 354.21
Purity: 98%
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| -- | -- | -- |
Density: 1.82±0.1 g/cm3
InChIKey: UAVXJXAREPXQGC-JXOAFFINSA-N
CanonicalSMILES: COC1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O
IUPAC Name: [(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methoxy-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
InChI: InChI=1S/C10H15N2O10P/c1-20-4-2-12(10(16)11-8(4)15)9-7(14)6(13)5(22-9)3-21-23(17,18)19/h2,5-7,9,13-14H,3H2,1H3,(H,11,15,16)(H2,17,18,19)/t5-,6-,7-,9-/m1/s1
Synonyms: ((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methoxy-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate; 5-Methoxy UMP; 5'-Uridylic acid, 5-methoxy-; 5-Methoxy-5'-uridylic acid; 5-Methoxyuridine 5'-phosphate; 5-OMe-UMP; 5-O-methyl-uridine-5'-monophosphate; 5-O-methyluridine-5'-monophosphate
Related CAS: 70406-74-5 (homopolymer)
6-Fluoro-3,4-dihydro-3-oxo-4-(5-O-phosphono-β-D-ribofuranosyl)-2-pyrazinecarboxamide ammonium salt
Description: 6-Fluoro-3,4-dihydro-3-oxo-4-(5-O-phosphono-β-D-ribofuranosyl)-2-pyrazinecarboxamide ammonium salt is a modified nucleoside phosphate used in biochemical and pharmaceutical research. The ammonium salt form enhances its solubility and stability. This nucleoside analog is often employed in studies of nucleic acid metabolism, enzyme interactions, and as a potential antiviral or anticancer agent, providing insights into therapeutic mechanisms and applications.
CAT: BRP-00809
CAS: 2096342-42-4
MF: C10H16FN4O9P
MF: 386.23
Purity: 98%
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Storage: Store at -20 °C, protect from light
InChIKey: LMKFDJHKHJFIBX-MGVVQUQWSA-N
CanonicalSMILES: O=C(N)C1=NC(F)=CN(C1=O)C2OC(COP(=O)(O)O)C(O)C2O.N
IUPAC Name: azanium;[(2R,3S,4R,5R)-5-(3-carbamoyl-5-fluoro-2-oxopyrazin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
InChI: InChI=1S/C10H13FN3O9P.H3N/c11-4-1-14(9(18)5(13-4)8(12)17)10-7(16)6(15)3(23-10)2-22-24(19,20)21;/h1,3,6-7,10,15-16H,2H2,(H2,12,17)(H2,19,20,21);1H3/t3-,6-,7-,10-;/m1./s1
Synonyms: 2-Pyrazinecarboxamide, 6-fluoro-3,4-dihydro-3-oxo-4-(5-O-phosphono-β-D-ribofuranosyl)-, ammonium salt (1:1); T-705RMP (ammonium); T 705RMP ammonium salt
Related CAS: 356783-08-9 (free base)
NaMTP
Description: NaMTP is a compound used in biochemical research and drug development. This compound is often studied for its potential biological activities and interactions, particularly in nucleotide metabolism and signaling pathways. Its structural complexity suggests possible roles in enzymatic processes or as a therapeutic target.
CAT: BRP-00819
CAS: 1135561-87-3
MF: C16H21O14P3
MF: 530.25
Purity: 95%
Appearance: Lyophilized white powder
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| -- | -- | -- |
Storage: Store at -20 °C
Density: 1.775±0.06 g/cm3
Boiling Point: 824.3±75.0 °C at 760 mmHg
InChIKey: CCJNXXZRNQFAFA-FPCVCCKLSA-N
Solubility: Soluble in Water
CanonicalSMILES: COC1=CC2=CC=CC=C2C=C1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
IUPAC Name: [[(2R,3S,4R,5S)-3,4-dihydroxy-5-(3-methoxynaphthalen-2-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C16H21O14P3/c1-26-12-7-10-5-3-2-4-9(10)6-11(12)16-15(18)14(17)13(28-16)8-27-32(22,23)30-33(24,25)29-31(19,20)21/h2-7,13-18H,8H2,1H3,(H,22,23)(H,24,25)(H2,19,20,21)/t13-,14-,15-,16+/m1/s1
Synonyms: (1S)-1,4-anhydro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-1-(3-methoxynaphthalen-2-yl)-D-ribitol; ((2R,3S,4R,5S)-3,4-dihydroxy-5-(3-methoxynaphthalen-2-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; D-Ribitol, 1,4-anhydro-1-C-(3-methoxy-2-naphthalenyl)-, 5-(tetrahydrogen triphosphate), (1S)-
NaMTP-CF2
Description: NaMTP-CF2 is a compound used in biochemical research and drug development. This compound is often studied for its potential biological activities and interactions, particularly in nucleotide metabolism and signaling pathways. Its structural complexity suggests possible roles in enzymatic processes or as a therapeutic target.
CAT: BRP-00820
MF: C17H21F2O13P3
MF: 564.26
Purity: 95%
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
InChIKey: QPQQKBQSGWQWPC-FPCVCCKLSA-N
Solubility: Soluble in Water
IUPAC Name: (((((((2R,3S,4R,5S)-3,4-dihydroxy-5-(3-methoxynaphthalen-2-yl)tetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)difluoromethyl)phosphonic acid
InChI: InChI=1S/C17H21F2O13P3/c1-29-12-7-10-5-3-2-4-9(10)6-11(12)16-15(21)14(20)13(31-16)8-30-35(27,28)32-34(25,26)17(18,19)33(22,23)24/h2-7,13-16,20-21H,8H2,1H3,(H,25,26)(H,27,28)(H2,22,23,24)/t13-,14-,15-,16+/m1/s1
Related CAS: 2095501-89-4 (2'-deoxy-NaMTP-CF2)
D-FMAUTP
Description: D-FMAUTP is a nucleotide analog compound with potential applications in antiviral drug development and nucleic acid chemistry research.
CAT: BRP-00829
CAS: 79551-89-6
MF: C10H16FN2O14P3
MF: 500.16
Purity: 95%
Appearance: Lyophilized white powder
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|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
Density: 1.97±0.1 g/cm3
InChIKey: RUKRVHYQIIURNV-JVZYCSMKSA-N
Solubility: Soluble in Water
CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)F
IUPAC Name: [[(2R,3R,4S,5R)-4-fluoro-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C10H16FN2O14P3/c1-4-2-13(10(16)12-8(4)15)9-6(11)7(14)5(25-9)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5-7,9,14H,3H2,1H3,(H,20,21)(H,22,23)(H,12,15,16)(H2,17,18,19)/t5-,6+,7-,9-/m1/s1
Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[2-deoxy-2-fluoro-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]-5-methyl-; (((2R,3R,4S,5R)-4-fluoro-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl)triphosphoric acid; 1-(2-Deoxy-2-fluoro-5-O-(hydroxy((hydroxy(phosphonooxy)phosphinyl)oxy)phosphinyl)-beta-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
(2'OMe-5'P-A)pG
Description: (2'OMe-5'P-A)pG is a modified nucleotide compound used in biochemical research. It consists of an adenosine nucleotide with a phosphonate group attached to the 5' carbon and a guanosine nucleotide linked to the 3' carbon via a phosphodiester bond. Additionally, the 2' position of the adenosine ribose is methylated. This compound is often utilized in studies related to RNA modification, enzymology, and nucleic acid chemistry, providing insights into RNA structure, function, and enzymatic mechanisms.
CAT: BRP-00904
CAS: 62828-60-8
MF: C21H28N10O14P2
MF: 706.46
Purity: >99%
Appearance: Lyophilized white powder
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| -- | -- | -- |
Storage: Store at -20 °C
Density: 2.36±0.1 g/cm3
InChIKey: XQBFQZRTNDQTOK-XPWFQUROSA-N
Solubility: Soluble in Water
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)N)COP(=O)(O)O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C5N=C(NC6=O)N)O)O
IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-methoxy-2-(phosphonooxymethyl)oxolan-3-yl] hydrogen phosphate
InChI: InChI=1S/C21H28N10O14P2/c1-40-14-13(8(3-41-46(35,36)37)44-20(14)30-5-26-9-15(22)24-4-25-16(9)30)45-47(38,39)42-2-7-11(32)12(33)19(43-7)31-6-27-10-17(31)28-21(23)29-18(10)34/h4-8,11-14,19-20,32-33H,2-3H2,1H3,(H,38,39)(H2,22,24,25)(H2,35,36,37)(H3,23,28,29,34)/t7-,8-,11-,12-,13-,14-,19-,20-/m1/s1
Synonyms: pApG dimer; 5'-phosphono-O2'-methyl-adenylyl-(3'->5')-guanosine; ((2R,3R,4R,5R)-3-(((((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methyl dihydrogen phosphate; Guanosine, 2'-O-methyl-5'-O-phosphonoadenylyl-(3'→5')-; 2'-O-Methyl-5'-O-phosphonoadenylyl-(3'→5')-guanosine; (2'OMe5'P A)pG; pA(2'-OMe)mpG
Related CAS: 2638447-50-2 (triethylamine salt (1:3)) ; 2894815-57-5 (triethylamine salt (1:2)) ; 2645354-91-0 (ammonium salt)
N7-Me-3'-OMe GDP
Description: N7-Me-3'-OMe GDP is a modified nucleotide compound used in biochemical research. It consists of guanosine diphosphate (GDP) with methylation at the N7 position of the guanine base and methylation at the 3' position of the ribose sugar. This modified nucleotide is used in studies related to RNA modification, RNA processing, and as a substrate analog in enzymatic assays, providing insights into RNA biology and enzymatic mechanisms.
CAT: BRP-00905
CAS: 400806-44-2
MF: C12H19N5O11P2
MF: 471.26
Purity: >99%
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
InChIKey: BYYIIJWDJDLPEV-IOSLPCCCSA-N
Solubility: Soluble in Water
CanonicalSMILES: O=C1N=C(N)NC2=C1[N+](=CN2C3OC(COP(=O)([O-])OP(=O)(O)O)C(OC)C3O)C
IUPAC Name: ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)methyl dihydrogen diphosphate
InChI: InChI=1S/C12H19N5O11P2/c1-16-4-17(9-6(16)10(19)15-12(13)14-9)11-7(18)8(25-2)5(27-11)3-26-30(23,24)28-29(20,21)22/h4-5,7-8,11,18H,3H2,1-2H3,(H5-,13,14,15,19,20,21,22,23,24)/t5-,7-,8-,11-/m1/s1
Synonyms: Guanosine 5'-(trihydrogen diphosphate), 7-methyl-3'-O-methyl-, inner salt; 3'-OMe-m7GDP
7-Methylguanosine diphosphate
Description: 7-Methylguanosine diphosphate is a modified nucleotide compound used in biochemical research. It consists of guanosine diphosphate (GDP) with methylation at the 7th position of the guanine base. This modified nucleotide is often used in studies related to RNA modification, mRNA capping, and as a substrate analog in enzymatic assays, providing insights into RNA biology and enzymatic mechanisms.
CAT: BRP-00906
CAS: 26467-11-8
MF: C11H17N5O11P2
MF: 457.23
Purity: >99%
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
InChIKey: SBASPRRECYVBRF-KQYNXXCUSA-N
Solubility: Soluble in Water
CanonicalSMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)O)O)O
IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-9-ium-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono phosphate
InChI: InChI=1S/C11H17N5O11P2/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24)/t4-,6-,7-,10-/m1/s1
Synonyms: Guanosine 5'-(trihydrogen diphosphate), 7-methyl-, inner salt; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy(phosphonooxy)phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-, inner salt; Purinium, 2-amino-1,6-dihydro-7-methyl-6-oxo-9-β-D-ribofuranosyl-, hydroxide, 5'-(trihydrogen pyrophosphate), inner salt; 7-Methyl-GDP; 7-Methylguanosine 5'-diphosphate; N7-Me GDP; m7GDP
Related CAS: 104809-16-7 (monosodium salt) ; 240137-50-2 (triethylamine salt (1:x)) ; 2173378-02-2 (triethylamine salt (1:1)) ; 1262968-09-1 (triethylamine salt (1:2))
2'-OMe-2-amino-ATP
Description: 2'-OMe-2-amino-ATP is a modified nucleotide used in biochemical and molecular biology research. It contains an adenosine base with a 2'-O-methyl modification and an amino group at the 2' position, linked to a triphosphate group. This modified nucleotide can be incorporated into RNA during transcription or into DNA during synthesis, allowing researchers to study its effects on RNA or DNA structure, stability, and function. It is particularly useful in investigations of RNA modification, RNA-protein interactions, and RNA catalysis due to its unique properties compared to natural nucleotides.
CAT: BRP-00924
CAS: 215942-59-9
MF: C11H19N6O13P3
MF: 536.22
Purity: 95%
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
Density: 2.51±0.1 g/cm3
Boiling Point: 995.1±75.0 °C at 760 mmHg
InChIKey: HZIXZQRCKAUTNV-KQYNXXCUSA-N
Solubility: Soluble in Water
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=C(N=C32)N)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
IUPAC Name: [[(2R,3R,4R,5R)-5-(2,6-diaminopurin-9-yl)-3-hydroxy-4-methoxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C11H19N6O13P3/c1-26-7-6(18)4(2-27-32(22,23)30-33(24,25)29-31(19,20)21)28-10(7)17-3-14-5-8(12)15-11(13)16-9(5)17/h3-4,6-7,10,18H,2H2,1H3,(H,22,23)(H,24,25)(H2,19,20,21)(H4,12,13,15,16)/t4-,6-,7-,10-/m1/s1
Synonyms: Adenosine 5'-(tetrahydrogen triphosphate), 2-amino-2'-O-methyl-; 2-Amino-2'-O-methyladenosine 5'-(tetrahydrogen triphosphate); 2-Amino-2'-O-methyl-ATP; 2-Amino-2'-O-methyladenosine 5'-triphosphate
4-F-UTP
Description: 4-F-UTP, or 4-Fluoro-uridine triphosphate, is a modified nucleotide used in biochemical and molecular biology research. It contains a uridine base with a fluorine atom substituted at the 4th position, linked to a triphosphate group. This modified nucleotide is employed in RNA labeling, where the fluorine substitution can be detected using fluorescence-based techniques. It is useful for studying RNA synthesis, processing, and degradation, as well as for labeling RNA probes in various molecular biology applications such as in situ hybridization and RNA imaging.
CAT: BRP-00925
CAS: 1251838-93-3
MF: C9H14FN2O15P3
MF: 502.13
Purity: 95%
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
Density: 2.13±0.1 g/cm3
InChIKey: JICLDCHIWOEHQY-JVZYCSMKSA-N
Solubility: Soluble in Water
CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)F)O)O
IUPAC Name: [[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-2-fluoro-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C9H14FN2O15P3/c10-9(3-24-29(20,21)27-30(22,23)26-28(17,18)19)6(15)5(14)7(25-9)12-2-1-4(13)11-8(12)16/h1-2,5-7,14-15H,3H2,(H,20,21)(H,22,23)(H,11,13,16)(H2,17,18,19)/t5-,6+,7-,9-/m1/s1
Synonyms: Uridine 5'-(tetrahydrogen triphosphate), 4'-C-fluoro-; 4'-C-Fluorouridine 5'-(tetrahydrogen triphosphate); ((2S,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-fluoro-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 4'-fluorouridine 5'-O-triphosphate
LNA-ATP
Description: LNA-ATP, or Locked Nucleic Acid-adenosine triphosphate, is a modified nucleotide used in biochemical and molecular biology research. It contains an adenosine base modified with a locked nucleic acid (LNA) backbone and linked to a triphosphate group. This modified nucleotide is utilized in studies related to RNA and DNA research, where LNA modifications enhance the stability and specificity of oligonucleotides. LNA-ATP can be incorporated into RNA or DNA strands during synthesis, allowing researchers to investigate various aspects of nucleic acid structure, function, and interactions.
CAT: BRP-00926
CAS: 941597-09-7
MF: C11H16N5O13P3
MF: 519.19
Purity: 95%
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
Density: 2.66±0.1 g/cm3
Boiling Point: 938.3±75.0 °C at 760 mmHg
InChIKey: IYXWSFFOIIMVHP-LRMGWDNHSA-N
Solubility: Soluble in Water
CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=NC4=C(N=CN=C43)N)O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O
IUPAC Name: [[(1R,3R,4R,7S)-3-(6-aminopurin-9-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C11H16N5O13P3/c12-8-5-9(14-3-13-8)16(4-15-5)10-6-7(17)11(27-10,1-25-6)2-26-31(21,22)29-32(23,24)28-30(18,19)20/h3-4,6-7,10,17H,1-2H2,(H,21,22)(H,23,24)(H2,12,13,14)(H2,18,19,20)/t6-,7+,10-,11-/m1/s1
Synonyms: 9H-Purin-6-amine, 9-[2,5-anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-; 9-[2,5-Anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-9H-purin-6-amine; ((1R,3R,4R,7S)-3-(6-amino-9H-purin-9-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl tetrahydrogen triphosphate; LNA-A-TP
LNA-GTP
Description: LNA-GTP, or Locked Nucleic Acid-guanosine triphosphate, is a modified nucleotide used in biochemical and molecular biology research. It contains a guanosine base modified with a locked nucleic acid (LNA) backbone and linked to a triphosphate group. This modified nucleotide is employed in studies related to RNA and DNA research, where LNA modifications enhance the stability and specificity of oligonucleotides. LNA-GTP can be incorporated into RNA or DNA strands during synthesis, enabling researchers to investigate various aspects of nucleic acid structure, function, and interactions.
CAT: BRP-00927
CAS: 1233876-29-3
MF: C11H16N5O14P3
MF: 535.19
Purity: 95%
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
Density: 2.79±0.1 g/cm3
Boiling Point: 1013.6±75.0 °C at 760 mmHg
InChIKey: PYKYQYMIAMREBH-HLJYALQUSA-N
Solubility: Soluble in Water
CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=NC4=C3N=C(NC4=O)N)O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O
IUPAC Name: [[(1R,3R,4R,7S)-3-(2-amino-6-oxo-1H-purin-9-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C11H16N5O14P3/c12-10-14-7-4(8(18)15-10)13-3-16(7)9-5-6(17)11(28-9,1-26-5)2-27-32(22,23)30-33(24,25)29-31(19,20)21/h3,5-6,9,17H,1-2H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,12,14,15,18)/t5-,6+,9-,11-/m1/s1
Synonyms: 6H-Purin-6-one, 2-amino-9-[2,5-anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-1,9-dihydro-; 2-Amino-9-[2,5-anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-1,9-dihydro-6H-purin-6-one; LNA-G-TP; ((1R,3R,4R,7S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl tetrahydrogen triphosphate
LNA-CTP
Description: LNA-CTP, or Locked Nucleic Acid-cytidine triphosphate, is a modified nucleotide used in biochemical and molecular biology research. It contains a cytidine base modified with a locked nucleic acid (LNA) backbone and linked to a triphosphate group. This modified nucleotide is utilized in studies related to RNA and DNA research, where LNA modifications enhance the stability and specificity of oligonucleotides. LNA-CTP can be incorporated into RNA or DNA strands during synthesis, allowing researchers to investigate various aspects of nucleic acid structure, function, and interactions.
CAT: BRP-00928
CAS: 847650-98-0
MF: C10H16N3O14P3
MF: 495.17
Purity: 95%
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
Density: 2.54±0.1 g/cm3
Boiling Point: 837.7±75.0 °C at 760 mmHg
InChIKey: LSTGCLQXGYREJT-IBCQBUCCSA-N
Solubility: Soluble in Water
CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=CC(=NC3=O)N)O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O
IUPAC Name: [[(1R,3R,4R,7S)-3-(4-amino-2-oxopyrimidin-1-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C10H16N3O14P3/c11-5-1-2-13(9(15)12-5)8-6-7(14)10(25-8,3-23-6)4-24-29(19,20)27-30(21,22)26-28(16,17)18/h1-2,6-8,14H,3-4H2,(H,19,20)(H,21,22)(H2,11,12,15)(H2,16,17,18)/t6-,7+,8-,10-/m1/s1
Synonyms: 2(1H)-Pyrimidinone, 4-amino-1-[2,5-anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-; 4-Amino-1-[2,5-anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-2(1H)-pyrimidinone; LNA-C-TP; ((1R,3R,4R,7S)-3-(4-amino-2-oxopyrimidin-1(2H)-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl tetrahydrogen triphosphate
LNA-UTP
Description: LNA-UTP, or Locked Nucleic Acid-uridine triphosphate, is a modified nucleotide used in biochemical and molecular biology research. It contains a uridine base modified with a locked nucleic acid (LNA) backbone and linked to a triphosphate group. This modified nucleotide is employed in studies related to RNA and DNA research, where LNA modifications enhance the stability and specificity of oligonucleotides. LNA-UTP can be incorporated into RNA strands during synthesis, allowing researchers to investigate various aspects of nucleic acid structure, function, and interactions.
CAT: BRP-00929
CAS: 1258616-54-4
MF: C10H15N2O15P3
MF: 496.15
Purity: 95%
Appearance: Lyophilized white powder
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Storage: Store at -20 °C
Density: 2.109±0.06 g/cm3
InChIKey: RSSDTUFQOLIPRO-IBCQBUCCSA-N
Solubility: Soluble in Water
CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=CC(=O)NC3=O)O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O
IUPAC Name: [[(1R,3R,4R,7S)-3-(2,4-dioxopyrimidin-1-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
InChI: InChI=1S/C10H15N2O15P3/c13-5-1-2-12(9(15)11-5)8-6-7(14)10(25-8,3-23-6)4-24-29(19,20)27-30(21,22)26-28(16,17)18/h1-2,6-8,14H,3-4H2,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18)/t6-,7+,8-,10-/m1/s1
Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[2,5-anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-; 1-[2,5-Anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-2,4(1H,3H)-pyrimidinedione; LNA-U-TP; ((1R,3R,4R,7S)-3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl tetrahydrogen triphosphate
5'-Ethyl dimethyl phosphonate-2'-OMe-U
Description: 5'-Ethyl dimethyl phosphonate-2'-OMe-U includes an ethyl dimethyl phosphonate group replaced to the 5' hydroxyl, along with a methyl (Me) group at the 2' position of ribose. It is used in oligonucleotide synthesis to introduce phosphonate modifications.
CAT: BRP-01014
MF: C13H21N2O8P
MF: 364.29
Purity: ≥98% by UPLC
Appearance: White, off-white to light yellow powder
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Storage: Store at -20 °C
InChIKey: HHIFIFUUIMPUDT-HJQYOEGKSA-N
IUPAC Name: dimethyl (2-((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)ethyl)phosphonate
InChI: InChI=1S/C13H21N2O8P/c1-20-11-10(17)8(5-7-24(19,21-2)22-3)23-12(11)15-6-4-9(16)14-13(15)18/h4,6,8,10-12,17H,5,7H2,1-3H3,(H,14,16,18)/t8-,10-,11-,12-/m1/s1
Synonyms: 5'-ethyl dimethyl phosphonate-2'-O-methyl-uridine
