Nucleotides - RNA / BOC Sciences

2-Aminoadenosine-5'-Triphosphate

Description: 2-Aminoadenosine-5'-Triphosphate, a versatile compound, finds extensive applications in enzymology and biotechnology as a substrate for kinases, ATPases, and nucleotide pyrophosphatases. Additionally, it is noteworthy for its ability to stimulate bone resorption activity in separated osteoclasts, therefore facilitating the study of bone metabolism and related diseases like osteoporosis and osteopenia.

CAT: BRP-01658

CAS: 18549-34-3

MF: C10H17N6O13P3

MF: 522.20

Purity: ≥90% by AX-HPLC

Appearance: Clear colorless to yellow liquid

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Storage: Store at -20°C

Density: 2.8±0.1 g/cm3

Boiling Point: 1045.8±75.0 °C at 760 mmHg

InChIKey: CABDYDUZLRXGTB-UUOKFMHZSA-N

CanonicalSMILES: C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N)N

IUPAC Name: [[(2R,3S,4R,5R)-5-(2,6-diaminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H17N6O13P3/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(18)5(17)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,17-18H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H4,11,12,14,15)/t3-,5-,6-,9-/m1/s1

Synonyms: 2-Amino-adenosine-5'-triphosphate; 2-NH2-ATP; 2-Amino-ATP; 2,6-Diaminopurine-ribose-5'-Triphosphate; DAP-rTP; 2-Aminoadenosine 5'-(tetrahydrogen triphosphate); 9H-Purine, 2,6-diamino-9-β-D-ribofuranosyl-, 5'-(tetrahydrogen triphosphate); 9H-Purine, 2,6-diamino-9-β-D-ribofuranosyl-, 5'-triphosphate; 2,6-Diaminopurine ribonucleoside triphosphate; 2,6-Diaminopurine riboside 5'-triphosphate; 2,6-Diaminopurine riboside triphosphate; 2,6-Diaminopurineribosyl-5'-triphosphate

8-Bromoadenosine 5'-Triphosphate Sodium Salt

Description: 8-Bromoadenosine 5'-Triphosphate Sodium Salt is a reagent required for the characterization (stoichiometry, geometry, and stability constant) of ATP:Fe(II) complex.

CAT: BRP-01659

CAS: 81035-56-5

MF: C10H15BrN5O13P3 (free acid)

MF: 586.08 (free acid)

Purity: ≥95% by HPLC

Appearance: Clear colorless to yellow liquid

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Storage: Store at -20 °C

InChIKey: CDLMOHDSMLZBCO-GWTDSMLYSA-M

CanonicalSMILES: C1=NC(=C2C(=N1)N(C(=N2)Br)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)[O-])O)O)N.[Na+]

IUPAC Name: sodium;[[[(2R,3S,4R,5R)-5-(6-amino-8-bromopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate

InChI: InChI=1S/C10H15BrN5O13P3.Na/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(18)5(17)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;/h2-3,5-6,9,17-18H,1H2,(H,22,23)(H,24,25)(H2,12,13,14)(H2,19,20,21);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

Synonyms: 8-bromo-adenosine-5'-triphosphate, sodium salt; 8-Br-ATP, Sodium Salt; 8-Bromo-adenosine 5'-(Tetrahydrogen triphosphate) Sodium Salt; Adenosine 5'-(tetrahydrogen triphosphate), 8-bromo-, sodium salt; 8-Bromo-ATP sodium salt

Related CAS: 23567-97-7 (free acid) ; 35892-96-7 (tetrasodium salt)

8-Bromo-ATP

Description: 8-Bromo-ATP is a potent analog of adenosine triphosphate (ATP), a crucial energy carrier in cells. Widely used in biomedicine, 8-Bromo-ATP exhibits high affinity towards purinergic receptors and is often employed to study their function and signaling pathways. Additionally, this compound serves as a substrate for various enzymatic reactions, enabling researchers to investigate ATP-dependent processes in drug discovery and disease mechanisms.

CAT: BRP-01660

CAS: 23567-97-7

MF: C10H15BrN5O13P3

MF: 586.08

Purity: ≥95% by HPLC

Appearance: clear aqueous solution

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Density: 2.85±0.1 g/cm3

Boiling Point: 983.1±75.0 °C at 760 mmHg

InChIKey: VPAHIVDZXBLTTM-UUOKFMHZSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C(=N2)Br)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

IUPAC Name: [[(2R,3S,4R,5R)-5-(6-amino-8-bromopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H15BrN5O13P3/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(18)5(17)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,17-18H,1H2,(H,22,23)(H,24,25)(H2,12,13,14)(H2,19,20,21)/t3-,5-,6-,9-/m1/s1

Synonyms: 8-Bromoadenosine 5'-Triphosphate; (8Br-ATP); 8-Br-ATP; 8-Bromoadenosine 5'-(tetrahydrogen triphosphate); Adenosine, 8-bromo-, 5'-(tetrahydrogen triphosphate); 8-Bromo ATP; 8-Bromoadenosine triphosphate; ((2R,3S,4R,5R)-5-(6-Amino-8-bromo-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate

Related CAS: 81035-56-5 (x-sodium salt) ; 35892-96-7 (tetrasodium salt)

8-Bromo-GTP

Description: 8-Bromo-GTP is a GTP analog that can inhibit GTP-hydrolase. It competitively inhibits GTPase (IC50 = 32 μM) and competes with ATP for the binding center of RNA-polymerase.

CAT: BRP-01661

CAS: 23197-98-0

MF: C10H15BrN5O14P3

MF: 602.08

Purity: ≥95% by HPLC

Appearance: clear aqueous solution

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Storage: Store at -20 °C

InChIKey: CNYUHYBBHQMZQJ-UMMCILCDSA-N

CanonicalSMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2Br)O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O

IUPAC Name: [[(2R,3S,4R,5R)-5-(2-amino-8-bromo-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChI: InChI=1S/C10H15BrN5O14P3/c11-9-13-3-6(14-10(12)15-7(3)19)16(9)8-5(18)4(17)2(28-8)1-27-32(23,24)30-33(25,26)29-31(20,21)22/h2,4-5,8,17-18H,1H2,(H,23,24)(H,25,26)(H2,20,21,22)(H3,12,14,15,19)/t2-,4-,5-,8-/m1/s1

Synonyms: (8Br-GTP); 8-Bromo-guanosine-5'-triphosphate; 8-Bromoguanosine 5'-triphosphate; 8-Bromoguanosine triphosphate

Guanylyl-(3',5')-adenosine

Description: Guanylyl-(3',5')-adenosine, a cyclic nucleotide second messenger, intricately orchestrates various cellular signaling pathways, rendering it crucial in regulating a myriad of physiological functions, ranging from neurotransmitter release to smooth muscle contraction. A versatile molecule of interest, this compound boasts promising potential in the therapeutic arena, especially for treating cardiovascular diseases, such as hypertension and heart failure, thanks to its adeptness in modulating platelet activation and gene expression.

CAT: BRP-01662

CAS: 6554-00-3

MF: C20H25N10O11P

MF: 612.45

Purity: ≥95% by AX-HPLC

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Storage: Store at -20°C

Density: 2.4±0.1 g/cm3

Boiling Point: 1147.4±75.0 °C at 760 mmHg

InChIKey: PBWYGOYNGCCLAU-INFSMZHSSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OC4C(OC(C4O)N5C=NC6=C5N=C(NC6=O)N)CO)O)O)N

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

InChI: InChI=1S/C20H25N10O11P/c21-14-8-15(24-3-23-14)29(4-25-8)18-11(33)10(32)7(40-18)2-38-42(36,37)41-13-6(1-31)39-19(12(13)34)30-5-26-9-16(30)27-20(22)28-17(9)35/h3-7,10-13,18-19,31-34H,1-2H2,(H,36,37)(H2,21,23,24)(H3,22,27,28,35)/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1

Synonyms: GmpA; Guanine ribonucleotidyl-(3'-5')-adenosine; Adenylyl-(5',3')-guanosine; GpA RNA Dinucleotide (5'-3'); GpA; Guanylyladenosine

Related CAS: 103213-26-9 (monoammonium salt) ; 21052-30-2 (x-ammonium salt) ; 103192-56-9 (monosodium salt)

Adenylyl-(3'-5')-cytidine

Description: Adenylyl-(3'-5')-cytidine is a nucleotide derivative involved in RNA metabolism and signaling pathways. It plays a role in various biological processes, including RNA modification and cellular signaling. Adenylyl-(3'-5')-cytidine is used in biochemical and molecular biology research to study RNA-related processes, including RNA capping mechanisms, mRNA processing, and interactions with enzymes involved in RNA metabolism. This compound serves as a model substrate to investigate RNA modification dynamics and its impact on RNA stability and function.

CAT: BRP-01663

CAS: 4833-63-0

MF: C19H25N8O11P

MF: 572.42

Purity: 95%

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Storage: Store at -20 °C

Density: 2.23±0.1 g/cm3

Boiling Point: 993.2±75.0 °C at 760 mmHg

InChIKey: NHEPQPHJXSVOGF-KPKSGTNCSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=NC5=C(N=CN=C54)N)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C19H25N8O11P/c20-9-1-2-26(19(32)25-9)17-12(30)11(29)8(37-17)4-35-39(33,34)38-14-7(3-28)36-18(13(14)31)27-6-24-10-15(21)22-5-23-16(10)27/h1-2,5-8,11-14,17-18,28-31H,3-4H2,(H,33,34)(H2,20,25,32)(H2,21,22,23)/t7-,8-,11-,12-,13-,14-,17-,18-/m1/s1

Synonyms: Cytidylyl(5'->3')adenosine; AmpC; 3'-Adenylic acid, 5'-ester with cytidine; Adenosine, cytidylyl-(5'→3')-; Adenylyl-(3'→5')-cytidine; Adenylylcytosine; ApC; NSC 131652; NSC 91551

Related CAS: 27553-02-2 (monoammonium salt) ; 63660-18-4 (x-ammonium salt) ; 25763-55-7 (monosodium salt)

Cytidylyl-(3'-5')-guanosine

Description: Cytidylyl-(3'-5')-guanosine is a pivotal compound entity, assuming a pivotal role in the intricacies of RNA synthesand serves as a potent catalyst for RNA-dependent protein kinase.

CAT: BRP-01664

CAS: 2382-65-2

MF: C19H25N8O12P

MF: 588.42

Purity: 95%

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Storage: Store at -20 °C

Density: 2.31±0.1 g/cm3

Boiling Point: 1057.6 °C at 760 mmHg

InChIKey: CTMZLDSMFCVUNX-VMIOUTBZSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C4NC(=NC5=O)N)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C19H25N8O12P/c20-8-1-2-26(19(33)23-8)17-12(31)13(6(3-28)37-17)39-40(34,35)36-4-7-10(29)11(30)16(38-7)27-5-22-9-14(27)24-18(21)25-15(9)32/h1-2,5-7,10-13,16-17,28-31H,3-4H2,(H,34,35)(H2,20,23,33)(H3,21,24,25,32)/t6-,7-,10-,11-,12-,13-,16-,17-/m1/s1

Synonyms: CmpG; Cytidylyl-3'-5'-guanosine; CpG RNA Dinucleotide (5'-3'); Cytidylyl-(3'→5')-guanosine; (3'-5')CpG; Cytidine, guanylyl-(5'→3')-; Cytidylylguanosine; Guanosine cytidine 3',5'-monophosphate; CpG

Related CAS: 27553-01-1 (monoammonia salt) ; 21052-28-8 (x-ammonium salt) ; 172793-57-6 (monosodium salt) ; 172793-58-7 (monopotassium salt)

Adenylyl-(3'-5')-adenosine

Description: Adenylyl-(3'-5')-adenosine is a pivotal biomolecule with extensive applications in studying signaling pathways, particularly cAMP-dependent processes. It aids in understanding cyclic nucleotide metabolism and exploring associated afflictions encompassing cancer, diabetes and cardiovascular disorders.

CAT: BRP-01665

CAS: 2391-46-0

MF: C20H25N10O10P

MF: 596.45

Purity: ≥98%

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Storage: Store at -20 °C

Density: 2.3±0.1 g/cm3

Boiling Point: 1081.3±75.0 °C at 760 mmHg

InChIKey: UYSXBCQACJTYFS-XPWFQUROSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OC4C(OC(C4O)N5C=NC6=C(N=CN=C65)N)CO)O)O)N

IUPAC Name: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C20H25N10O10P/c21-15-9-17(25-3-23-15)29(5-27-9)19-12(33)11(32)8(39-19)2-37-41(35,36)40-14-7(1-31)38-20(13(14)34)30-6-28-10-16(22)24-4-26-18(10)30/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H2,21,23,25)(H2,22,24,26)/t7-,8-,11-,12-,13-,14-,19-,20-/m1/s1

Synonyms: ApA RNA Dinucleotide (5'-3'); AmpA; 5'-Adenylic acid, 3'-ester with adenosine; 3',5'-ApA; D-Adenylyl-(3'-5')-D-adenosine; Adenylyl-(5'→3')-adenosine; Adenylyladenosine; Diadenosine 3',5'-monophosphate; NSC 91555; ApA

Related CAS: 102029-96-9 (monoammonia salt) ; 21027-46-3 (x-ammonium salt) ; 61240-16-2 (monosodium salt)

Guanylyl-(3'-5')-cytidine

Description: Guanylyl-3',5'-cytidine, a biochemical compound, is a valuable tool in the biomedical industry for delving deep into the intricacies of RNA capping mechanisms. It mimics guanosine 5’-triphosphate (GTP), a naturally occurring molecule, and is utilized to investigate the cellular processes of various RNA viruses, including hepatitis C virus (HCV). Furthermore, guanylyl-3',5'-cytidine holds the promise of therapeutic benefits for HCV and other RNA viral infections.

CAT: BRP-01666

CAS: 4785-04-0

MF: C19H25N8O12P

MF: 588.42

Purity: 95%

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Storage: Store at -20 °C

Density: 2.31±0.1 g/cm3

Boiling Point: 1057.6 °C at 760 mmHg

InChIKey: DQTQQHQGSZWEMR-VMIOUTBZSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=NC5=C4NC(=NC5=O)N)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

InChI: InChI=1S/C19H25N8O12P/c20-8-1-2-26(19(33)23-8)16-11(30)10(29)7(38-16)4-36-40(34,35)39-13-6(3-28)37-17(12(13)31)27-5-22-9-14(27)24-18(21)25-15(9)32/h1-2,5-7,10-13,16-17,28-31H,3-4H2,(H,34,35)(H2,20,23,33)(H3,21,24,25,32)/t6-,7-,10-,11-,12-,13-,16-,17-/m1/s1

Synonyms: Guanylyl-3',5'-cytidine; Guanylyl-(3',5')-cytidine; GpC RNA Dinucleotide (5'-3'); Cytidylyl-(5'->3')-guanosine; 3'-Guanylic acid, 5'-ester with cytidine; Guanosine, cytidylyl-(5'→3')-; Guanylyl-(3'→5')-cytidine; GC; GpC

Related CAS: 98046-67-4 (monoammonia salt) ; 84825-35-4 (monoammonia salt octahydrate) ; 98046-66-3 (monosodium salt) ; 55015-32-2 (calcium salt (2:1)) ; 172793-59-8 (monopotassium salt)

Uridylyl-(3'-5')-cytidine

Description: Uridylyl-(3'-5')-cytidine, a pivotal enzyme central to the biomedicine sector, exhibits invaluable utility for combatting select viral infections and malignancies. Its significance lies in RNA synthesis, bolstering cellular functionality and resilience.

CAT: BRP-01667

CAS: 3013-97-6

MF: C18H24N5O13P

MF: 549.40

Purity: ≥95% by AX-HPLC

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Storage: Store at -20 °C

Density: 2.13±0.1 g/cm3

InChIKey: LENQVXALZPDAFB-NCOIDOBVSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=CC(=O)NC4=O)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C18H24N5O13P/c19-9-1-3-22(17(29)20-9)15-12(27)11(26)8(35-15)6-33-37(31,32)36-14-7(5-24)34-16(13(14)28)23-4-2-10(25)21-18(23)30/h1-4,7-8,11-16,24,26-28H,5-6H2,(H,31,32)(H2,19,20,29)(H,21,25,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1

Synonyms: UpC RNA Dinucleotide (5'-3'); Cytidylyl-(5',3')-uridine; 3'-Uridylic acid, 5'-ester with cytidine; Uridine, cytidylyl-(5'→3')-; Uridylyl-(3'→5')-cytidine; Cytidylyl-(5'→3')-uridine; NSC 131649

Related CAS: 27531-20-0 (monoammonia salt) ; 108347-78-0 (x-ammonium salt) ; 30796-28-2 (polymers)

Guanylyl-(3'-5')-guanosine

Description: Guanylyl-(3'-5')-guanosine is a highly significant compound extensively employed in biomedical research, emerging as an indispensable player in signal transduction. Its pivotal role lies in its capacity to function as a second messenger molecule, especially in the modulation of cyclic GMP levels. Diverse cellular phenomena, encompassing vasodilation, neurotransmission and immune responses is are meticulously investigated utilizing this molecule to scrutinize the cGMP-dependent pathways.

CAT: BRP-01668

CAS: 3353-33-1

MF: C20H25N10O12P

MF: 628.45

Purity: ≥95% by AX-HPLC

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Storage: Store at -20 °C

Density: 2.5±0.1 g/cm3

Boiling Point: 1215.2±75.0 °C at 760 mmHg

InChIKey: MNXLMHSUERRXOE-MHARETSRSA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OC4C(OC(C4O)N5C=NC6=C5N=C(NC6=O)N)CO)O)O)N=C(NC2=O)N

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C20H25N10O12P/c21-19-25-13-7(15(35)27-19)23-3-29(13)17-10(33)9(32)6(41-17)2-39-43(37,38)42-12-5(1-31)40-18(11(12)34)30-4-24-8-14(30)26-20(22)28-16(8)36/h3-6,9-12,17-18,31-34H,1-2H2,(H,37,38)(H3,21,25,27,35)(H3,22,26,28,36)/t5-,6-,9-,10-,11-,12-,17-,18-/m1/s1

Synonyms: GpG RNA Dinucleotide (5'-3'); 3'-Guanylic acid, 3',5'-ester with guanosine; Guanylyl-(3'→5')-guanosine; GmpG; GpG; Guanosyl(3',5')guanosine

Related CAS: 97403-87-7 (monoammonia salt) ; 21052-31-3 (x-ammonium salt) ; 137629-38-0 (TEA salt) ; 49717-61-5 (homopolymer) ; 146819-37-6 (x-sodium salt) ; 146819-38-7 (x-potassium salt) ; 146819-36-5 (x-lithium salt)

Cytidylyl-(3'-5')-cytidine

Description: Cytidylyl-(3'-5')-cytidine is a biochemical utilized in the production of RNA. It also plays a crucial role in signaling pathways. In the biomedical field, it is being researched as a potential treatment for certain cancers, such as pancreatic cancer.

CAT: BRP-01669

CAS: 2536-99-4

MF: C18H25N6O12P

MF: 548.40

Purity: ≥95% by AX-HPLC

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Storage: Store at -20°C

Density: 2.13±0.1 g/cm3

Boiling Point: 905.8±75.0 °C at 760 mmHg

InChIKey: PTLMIIUMLITBQT-NCOIDOBVSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=CC(=NC4=O)N)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C18H25N6O12P/c19-9-1-3-23(17(29)21-9)15-12(27)11(26)8(35-15)6-33-37(31,32)36-14-7(5-25)34-16(13(14)28)24-4-2-10(20)22-18(24)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H2,19,21,29)(H2,20,22,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1

Synonyms: CpC RNA Dinucleotide (5'-3'); CmpC; 3'-Cytidylic acid, 5'-ester with cytidine; Cytidylyl-(3'→5')-cytidine; CpC; NSC 131650; NSC 91550

Related CAS: 27552-98-3 (monoammonia salt)

Guanylyl-(3'-5')-uridine

Description: Guanylyl-(3'-5')-uridine is a dinucleotide derivative that participates in RNA capping processes. It is involved in the addition of a guanosine cap to the 5' end of RNA molecules during RNA processing, essential for mRNA stability and translation initiation. It is utilized in biochemical and molecular biology research to investigate RNA-related processes, including RNA capping mechanisms, mRNA processing, and interactions with RNA-binding proteins. This compound serves as a valuable tool in elucidating the roles of modified nucleotides in RNA biology and in studying enzymatic reactions involving RNA molecules.

CAT: BRP-01670

CAS: 4785-07-3

MF: C19H24N7O13P

MF: 589.41

Purity: ≥98%

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Storage: Store at -20 °C

Density: 2.31±0.1 g/cm3

InChIKey: HQXUOLIEBGPXRE-VMIOUTBZSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=NC5=C4N=C(NC5=O)N)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

InChI: InChI=1S/C19H24N7O13P/c20-18-23-14-9(15(32)24-18)21-5-26(14)17-12(31)13(6(3-27)37-17)39-40(34,35)36-4-7-10(29)11(30)16(38-7)25-2-1-8(28)22-19(25)33/h1-2,5-7,10-13,16-17,27,29-31H,3-4H2,(H,34,35)(H,22,28,33)(H3,20,23,24,32)/t6-,7-,10-,11-,12-,13-,16-,17-/m1/s1

Synonyms: GmpU; Guanylyl(3'-5')uridine; 3'-Guanylic acid, 5'-ester with uridine; Guanosine, uridylyl-(5'→3')-; Guanylyl-(3'→5')-uridine; GU; Guanosyl-(3',5')-uridine; Guanylyl-(3',5')-uridine; NSC 92173; GU dinucleotide

Related CAS: 41547-83-5 (monoammonia salt) ; 21052-32-4 (x-ammonium salt) ; 27531-23-3 (TEA salt)

Adenylyl-(3'-5')-guanosine

Description: ADENYLYL-(3'-5')-GUANOSINE, a fundamental molecule in cellular signaling pathways, is an indispensable regulator of intracellular communication. It assumes a pivotal position in the control of diverse biological phenomena encompassing DNA synthesis and repair, cell growth, as well as immune responses. In the realm of biomedicine, ADENYLYL-(3'-5')-GUANOSINE finds utility in the investigation of second messenger signaling, cyclic nucleotide regulation, and the therapeutic management of afflictions including cancer, cardiovascular disorders, and neurodegenerative conditions.

CAT: BRP-01671

CAS: 3352-23-6

MF: C20H25N10O11P

MF: 612.45

Purity: ≥95%

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Storage: Store at -20°C

Density: 2.41±0.1 g/cm3

Boiling Point: 1147.4±75.0 °C at 760 mmHg

InChIKey: LWBLDUTUVIXFJE-INFSMZHSSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C5N=C(NC6=O)N)O)O)O)N

IUPAC Name: [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C20H25N10O11P/c21-14-8-15(24-3-23-14)29(4-25-8)19-12(34)13(6(1-31)39-19)41-42(36,37)38-2-7-10(32)11(33)18(40-7)30-5-26-9-16(30)27-20(22)28-17(9)35/h3-7,10-13,18-19,31-34H,1-2H2,(H,36,37)(H2,21,23,24)(H3,22,27,28,35)/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1

Synonyms: Guanosine, adenylyl-(3'→5')-; 3'-Adenylic acid, 5'-ester with guanosine; Adenylyl-(3'→5')-guanosine; A-G; Adenosine, guanylyl-(5'→3')-; NSC 91554; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl) hydrogen phosphate; 3'-O-(5'-Guanylyl)adenosine

Related CAS: 102029-53-8 (monoammonia salt) ; 21027-47-4 (x-ammonium salt) ; 30796-29-3 (polymers)

Adenylyl-3'-5'-cytidine

Description: Adenylyl-3'-5'-cytidine is a highly effective and specialized adenylyl cyclase activator, holding applications in biomedical research for investigating the cyclic adenosine monophosphate (cAMP) signaling pathways.

CAT: BRP-01672

CAS: 2382-66-3

MF: C19H25N8O11P

MF: 572.42

Purity: 98%

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Storage: Store at -20 °C

Density: 2.23±0.1 g/cm3

Melting Point: 173-175 °C

Boiling Point: 993.2±75.0 °C at 760 mmHg

Application: Enzyme Inhibitors

InChIKey: ZLVJWOGZEAIPAO-KPKSGTNCSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

InChI: InChI=1S/C19H25N8O11P/c20-9-1-2-26(19(32)25-9)18-13(31)14(7(3-28)36-18)38-39(33,34)35-4-8-11(29)12(30)17(37-8)27-6-24-10-15(21)22-5-23-16(10)27/h1-2,5-8,11-14,17-18,28-31H,3-4H2,(H,33,34)(H2,20,25,32)(H2,21,22,23)/t7-,8-,11-,12-,13-,14-,17-,18-/m1/s1

Synonyms: CmpA; Adenylyl-3'-5'-D-cytidine; 5'-Adenylic acid, 3'-ester with cytidine; Cytidylyl-(3'→5')-adenosine; Cytidine, adenylyl-(5'→3')-; Cytidylyl-3',5'-adenosine; NSC 91552; Cytidylyl adenosine; Cytidylyl-3',5'-adenosine phosphate; (3'-5')CpA; Cytidylyl-(3'-5')-adenosine; CpA; Cytidylyl(3',5')adenosine

Related CAS: 27553-00-0 (monoammonia salt) ; 21052-27-7 (x-ammonium salt) ; 25602-07-7 (monosodium salt) ; 63660-19-5 (x-sodium salt)

Uridylyl-(3'-5')-adenosine

Description: Uridylyl-(3'-5')-adenosine, an indispensable enzyme in the field of biomedicine, holds immense significance owing to its pivotal role in nucleotide metabolism. Its involvement in the synthesis of flavin adenine dinucleotide (FAD), a fundamental coenzyme for diverse enzymatic reactions, further amplifies its importance. Prominently employed for investigating FAD-dependent enzymes and their potential implications in a wide array of ailments like cancer, cardiovascular disorders, and neurodegenerative conditions, this product emerges as a scholarly tool in scientific exploration.

CAT: BRP-01673

CAS: 3256-24-4

MF: C19H24N7O12P

MF: 573.40

Purity: ≥95% by AX-HPLC

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Storage: Store at -20 °C

Density: 2.23±0.1 g/cm3

InChIKey: SWTWQWKNQDDGCS-KPKSGTNCSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C19H24N7O12P/c20-15-10-16(22-5-21-15)26(6-23-10)17-12(30)11(29)8(37-17)4-35-39(33,34)38-14-7(3-27)36-18(13(14)31)25-2-1-9(28)24-19(25)32/h1-2,5-8,11-14,17-18,27,29-31H,3-4H2,(H,33,34)(H2,20,21,22)(H,24,28,32)/t7-,8-,11-,12-,13-,14-,17-,18-/m1/s1

Synonyms: UpA RNA Dinucleotide (5'-3'); Uridylyladenosine; Uridine-3',5'-adenosine phosphate; (3',5')-Uridylyladenosine; 5'-Adenylic acid, ester with uridine-(5'→3'); Uridylyl-(3'→5')-adenosine; (3'-5')UpA; Adenosine 5',3'-phosphouridine; NSC 118092; UmpA; UpA

Related CAS: 27531-21-1 (monoammonia salt) ; 21052-33-5 (x-ammonium salt) ; 160509-67-1 (monosodium salt) ; 35523-12-7 (hemihydrate)

Uridylyl-(3'-5')-uridine

Description: Uridylyl-(3'-5')-uridine is a dinucleotide derivative where uridine is linked via a 3',5'-phosphodiester bond to another uridine molecule. It is used in biochemical and molecular biology research to study RNA-related processes, including RNA capping mechanisms, mRNA processing, and interactions with RNA-binding proteins. This nucleotide derivative plays a significant role in investigating RNA structure, function, and enzymatic reactions involving RNA molecules.

CAT: BRP-01674

CAS: 2415-43-2

MF: C18H23N4O14P

MF: 550.37

Purity: ≥95% by AX-HPLC

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Storage: Store at -20 °C

Density: 1.88±0.1 g/cm3

InChIKey: KXSPLNAXPMVUEC-NCOIDOBVSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=CC(=O)NC4=O)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate

InChI: InChI=1S/C18H23N4O14P/c23-5-7-14(13(28)16(34-7)22-4-2-10(25)20-18(22)30)36-37(31,32)33-6-8-11(26)12(27)15(35-8)21-3-1-9(24)19-17(21)29/h1-4,7-8,11-16,23,26-28H,5-6H2,(H,31,32)(H,19,24,29)(H,20,25,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1

Synonyms: UpU RNA Dinucleotide (5'-3'); Uridine monophosphate-uridine; UmpU; Uridylyl-(3'→5')-uridine; 5'-Uridylic acid, 3'-ester with uridine; (3',5')-Uridylyluridine; Uridylyl-3',5'-uridine; UpU

Related CAS: 27552-95-0 (monoammonia salt) ; 21052-35-7 (x-ammonium salt) ; 18531-27-6 (monosodium salt) ; 101609-06-7 (TEA salt)

Adenylyl-(3'-5')-uridine

Description: Adenylyl-(3'-5')-uridine is a dinucleotide structure involved in RNA editing and modification processes. It plays a role in post-transcriptional modification by adding an adenylyl group to the 3' end of uridine in RNA molecules. This modification can affect RNA stability, structure, and function, influencing various cellular processes.

CAT: BRP-01675

CAS: 3051-84-1

MF: C19H24N7O12P

MF: 573.41

Purity: 95%

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Storage: Store at -20 °C

Density: 19.65 g/cm3

Melting Point: 210 °C

InChIKey: RNNPIPQLZRGXIG-KPKSGTNCSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=NC5=C(N=CN=C54)N)CO)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

InChI: InChI=1S/C19H24N7O12P/c20-15-10-16(22-5-21-15)26(6-23-10)18-13(31)14(7(3-27)36-18)38-39(33,34)35-4-8-11(29)12(30)17(37-8)25-2-1-9(28)24-19(25)32/h1-2,5-8,11-14,17-18,27,29-31H,3-4H2,(H,33,34)(H2,20,21,22)(H,24,28,32)/t7-,8-,11-,12-,13-,14-,17-,18-/m1/s1

Synonyms: Adenylyl-(3'→5')-uridine; AmpU; 3'-Adenylic acid, ester with uridine-(3'→5'); Adenosine, uridylyl-(5'→3')-; Adenylyluridine; NSC 92172; Uridylyl-(5'→3')-adenosine

Related CAS: 93839-87-3 (monoammonia salt) ; 18424-35-6 (x-calcium salt) ; 43150-64-7 (monosodium salt) ; 60031-89-2 (monosodium salt hexahydrate)

Cytidylyl(3'-5')uridine

Description: Cytidylyl(3'-5')uridine, a critical biochemical intermediate imperative in nucleotide metabolism, presents as a promising therapeutic agent for various ailments. Such ailments involve, but are not limited to, viral infections and certain cancerous illnesses. Moreover, this novel product provides researchers with an advantageous tool in understanding the molecular mechanisms that facilitate nucleotide biosynthesis and metabolism.

CAT: BRP-01676

CAS: 2382-64-1

MF: C18H24N5O13P

MF: 549.38

Purity: ≥95% by AX-HPLC

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Storage: Store at -20°C

Density: 8.3 g/cm3

InChIKey: VSIFECIDUDPNRC-NCOIDOBVSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)OP(=O)(O)OCC3C(C(C(O3)N4C=CC(=O)NC4=O)O)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

InChI: InChI=1S/C18H24N5O13P/c19-9-1-3-22(17(29)20-9)16-13(28)14(7(5-24)34-16)36-37(31,32)33-6-8-11(26)12(27)15(35-8)23-4-2-10(25)21-18(23)30/h1-4,7-8,11-16,24,26-28H,5-6H2,(H,31,32)(H2,19,20,29)(H,21,25,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1

Synonyms: Cytidylyl-(3',5')-uridine; CpU RNA Dinucleotide (5'-3'); 5'-Uridylic acid, 3'-ester with cytidine; Cytidylyl-(3'→5')-uridine; Cytidine, uridylyl-(5'→3')-; NSC 118091; CmpU

Related CAS: 27552-97-2 (monoammonia salt) ; 21052-29-9 (x-ammonia salt)

Uridine-5'-diphosphate trisodium salt

Description: Uridine-5'-diphosphate trisodium salt is an indispensable biochemical compound utilized extensively in the nucleic acid synthesis and glycogen metabolism research. Within the tapestry of scientific exploration, Uridine-5'-diphosphate trisodium salt emerges as a pivotal player, intimately intertwined with the intricate fabric of RNA metabolism assessment, viral replication elucidation and the research of afflictions such as cancer and neurological disorders.

CAT: BRP-01679

CAS: 19817-91-5

MF: C9H11N2Na3O12P2

MF: 470.11

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at -20 °C

Melting Point: >144°C (dec.)

InChIKey: GFASEGWJDXDCKZ-LLWADOMFSA-K

Solubility: Soluble in Water (Slightly)

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])[O-])O)O.[Na+].[Na+].[Na+]

IUPAC Name: trisodium;[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate

InChI: InChI=1S/C9H14N2O12P2.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1

Synonyms: 5'-UDP.Na3; Uridine 5'-(trihydrogendiphosphate), trisodium salt; ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl diphosphate trisodium salt; trisodium uridine 5'-diphosphate; Uridine, 5'-(trihydrogen diphosphate), sodium salt (1:3); Trisodium UDP; UDP trisodium salt

Related CAS: 123334-08-7 (x-hydrate) ; 58-98-0 (free acid)