Nucleotides

Description: ADP-heptose is a molecule composed of adenosine diphosphate (ADP) linked to a heptose sugar molecule. Heptose sugars are commonly found in bacterial lipopolysaccharides (LPS) and are crucial for the structural integrity and immunogenicity of these molecules. ADP-heptose is involved in the biosynthesis of LPS, which is an essential component of the outer membrane of Gram-negative bacteria. LPS plays a critical role in bacterial virulence and host-pathogen interactions. Studying ADP-heptose can provide insights into bacterial physiology, pathogenesis, and potential targets for antibiotic development.

CAT: BRP-00667

CAS: 322640-28-8

MF: C17H27N5O16P2

MF: 619.37

Purity: ≥95%

Description: pUTP Tris salt is a nucleotide analog of uridine triphosphate (UTP) wherein uracil is substituted with pseudouridine (Ψ). This modification mimics natural RNA structures and functions, enhancing its utility in RNA-related research. The addition of Tris salt improves its solubility and stability, making it suitable for various molecular biology applications. Common uses include RNA labeling, in vitro transcription assays, and studying RNA modifications, offering insights into RNA biology and potential therapeutic avenues.

CAT: BRP-00668

MF: C9H15N2O15P3 (free acid)

MF: 484.14 (free acid)

Purity: >99%

Description: 2'-O-4'-C-Locked-m7GMP sodium salt is a modified form of guanosine monophosphate (GMP) where a locked nucleic acid (LNA) modification is incorporated at the 2' position and a 4'-carbon linkage (4'-C) is present. Additionally, it contains a 7-methylguanosine (m7G) cap. The locked nucleic acid modification enhances the compound's stability and hybridization affinity, making it useful for various biochemical applications, particularly in RNA research. The addition of a sodium salt enhances the compound's solubility and stability in aqueous solutions. This modified nucleotide is commonly used in enzymatic reactions, RNA capping studies, and investigations of mRNA processing and translation mechanisms due to its resemblance to the structure of eukaryotic mRNA caps.

CAT: BRP-00669

MF: C12H16N5O8P (free acid)

MF: 389.26 (free acid)

Purity: >98%

Description: 2'-O-4'-C-Locked-m7GMP Ammonium salt is a modified derivative of guanosine monophosphate (GMP) where a locked nucleic acid (LNA) modification is incorporated at the 2' position and a 4'-carbon linkage (4'-C) is present, along with a 7-methylguanosine (m7G) cap. The locked nucleic acid modification enhances the stability and hybridization affinity of the compound, making it valuable in biochemical applications, especially in RNA research. The inclusion of an ammonium salt further improves its solubility and stability, particularly in aqueous solutions. This modified nucleotide is commonly used in various molecular biology techniques, such as enzymatic reactions, RNA capping studies, and investigations into mRNA processing and translation mechanisms. Its structure closely resembles that of eukaryotic mRNA caps, making it a useful tool for studying mRNA-related processes in biological systems.

CAT: BRP-00670

MF: C12H16N5O8P (free acid)

MF: 389.26 (free acid)

Purity: >98%

Description: 2'-O-4'-C-Locked-GMP TEA Salt is a modified form of guanosine monophosphate (GMP) where a locked nucleic acid (LNA) modification is incorporated at the 2' position and a 4'-carbon linkage (4'-C) is present. This modification enhances the stability and hybridization affinity of the nucleotide, making it useful for various biochemical applications, particularly in RNA research. The addition of a TEA (triethylammonium) salt further improves its solubility and stability in aqueous solutions. Common uses of 2'-O-4'-C-Locked-GMP TEA Salt include enzymatic reactions, RNA capping studies, and investigations into mRNA processing and translation mechanisms. Its structure closely resembles that of eukaryotic mRNA caps, making it a valuable tool for studying mRNA-related processes in biological systems.

CAT: BRP-00671

MF: C11H14N5O8P (free acid)

MF: 375.23 (free acid)

Purity: >98%

Description: 2'-O-4'-C-Locked-m7GMP TEA Salt is a modified form of guanosine monophosphate (GMP) where a locked nucleic acid (LNA) modification is incorporated at the 2' position and a 4'-carbon linkage (4'-C) is present. Additionally, it contains a 7-methylguanosine (m7G) cap. The locked nucleic acid modification enhances the compound's stability and hybridization affinity, making it useful for various biochemical applications, particularly in RNA research. The addition of a TEA (triethylammonium) salt enhances its solubility and stability in aqueous solutions. This modified nucleotide is commonly used in enzymatic reactions, RNA capping studies, and investigations of mRNA processing and translation mechanisms due to its resemblance to the structure of eukaryotic mRNA caps.

CAT: BRP-00672

MF: C12H16N5O8P (free acid)

MF: 389.26 (free acid)

Purity: >98%

Description: 3'-OMe-m7GMP sodium salt is a chemical compound derived from guanosine monophosphate (GMP) where a methyl group is added to the 3' position and a 7-methylguanosine (m7G) cap is present. This modification mimics the structure of the 5' cap found in eukaryotic mRNA, which plays a crucial role in mRNA stability, translation initiation, and mRNA splicing. The addition of a sodium salt enhances the compound's solubility and stability, making it suitable for various biochemical applications, particularly in RNA research. This modified nucleotide is commonly used as a substrate in enzymatic reactions, RNA capping studies, and as a tool for investigating mRNA processing and translation mechanisms.

CAT: BRP-00673

MF: C12H18N5O8P (free acid)

MF: 391.27 (free acid)

Purity: >98%

Description: Cy5-UTP sodium salt is a modified form of uridine triphosphate (UTP) with a Cyanine 5 (Cy5) fluorescent dye attached to the 5th position of the uracil base. This modification enables the labeling of RNA molecules during transcription, allowing for their visualization and detection in various biological assays. The addition of a sodium salt enhances the compound's solubility and stability, making it suitable for applications in molecular biology and biochemistry. Cy5-UTP sodium salt is commonly used in RNA labeling techniques, fluorescence in situ hybridization (FISH) assays, real-time monitoring of RNA synthesis and degradation pathways, and the visualization of RNA localization within cells. This compound serves as a valuable tool for studying gene expression, RNA trafficking, and other RNA-related processes in biological systems, contributing significantly to our understanding of cellular function and regulation.

CAT: BRP-00674

MF: C45H58N5O22P3S2 (free acid)

MF: 1178.01 (free acid)

Purity: >95%

Description: 5-OMe-UTP TEA Salt is a modified form of uridine triphosphate (UTP) where a methoxy (OMe) group is attached to the 5th position of the uracil base. This modification enables UTP to be utilized in various biochemical applications. Additionally, the compound exists in the form of a TEA (triethylammonium) salt, enhancing its solubility and stability in aqueous solutions. 5-OMe-UTP TEA Salt is commonly employed in molecular biology research for RNA labeling, RNA-protein interaction studies, and in vitro transcription assays. Its binding during transcription allows for the specific detection and manipulation of RNA molecules in experimental settings. The TEA salt form ensures ease of handling and compatibility with biological assays, making it a valuable tool in RNA-related research endeavors.

CAT: BRP-00675

MF: C10H17N2O16P3 (free acid)

MF: 514.17 (free acid)

Purity: >98%

Description: Cy3-UTP sodium salt is a modified form of uridine triphosphate (UTP) with a Cyanine 3 (Cy3) fluorescent dye attached to the 5th position of the uracil base. This modification allows for the labeling of RNA molecules during transcription, enabling their visualization in biological assays. The sodium salt addition enhances solubility and stability, making it useful in molecular biology applications such as RNA labeling, fluorescence in situ hybridization (FISH), and real-time RNA detection, aiding research in gene expression and RNA biology.

CAT: BRP-00676

MF: C43H56N5O22P3S2 (free acid)

MF: 1151.98 (free acid)

Purity: >95%

Description: Fluorescein-12-UTP sodium salt is a modified form of uridine triphosphate (UTP) where a fluorescein molecule is attached to the 5th position of the uracil base. This modification allows for the incorporation of a fluorescent tag into RNA molecules during transcription, enabling their visualization and detection in various biological assays. The addition of a sodium salt enhances the compound's solubility and stability, making it well-suited for applications such as RNA labeling, fluorescence in situ hybridization (FISH), and real-time monitoring of RNA synthesis and degradation processes.

CAT: BRP-00677

MF: C39H41N4O22P3 (free acid)

MF: 1010.68 (free acid)

Purity: >95%

Description: ATP(αS) sodium salt is a chemical compound wherein the sulfur (S) atom is substituted for oxygen (O) at the α-phosphate position of adenosine triphosphate (ATP). This modification, known as α-thio substitution, alters the chemical properties of ATP, making it resistant to hydrolysis by certain enzymes. The addition of a sodium salt enhances the compound's solubility and stability, making it valuable for biochemical research. ATP(αS) sodium salt is often utilized in studies focusing on ATP-binding proteins, enzyme kinetics, and elucidating cellular signaling pathways.

CAT: BRP-00678

MF: C10H16N5O12P3S (free acid)

MF: 523.24 (free acid)

Purity: >98%

Appearance: Colorless to light yellow liquid

Description: N,N-Dimethyl-ATP sodium salt is a chemical compound derived from adenosine triphosphate (ATP) by adding dimethyl groups. This modification is often employed in biochemical research due to its altered properties. N,N-Dimethyl-ATP sodium salt has been investigated for its potential effects on cellular processes and signaling pathways, contributing to the understanding of ATP's role in various biological mechanisms. The presence of sodium ions in its salt form enhances its solubility and stability, making it more suitable for experimental use.

CAT: BRP-00679

MF: C12H20N5O13P3 (free acid)

MF: 535.23 (free acid)

Purity: >98%

Description: SPS ATP sodium salt is a compound commonly used in biochemical research. It serves as an analog of adenosine triphosphate (ATP) and is often employed in enzymatic assays and studies involving ATP-dependent processes. This salt form contains sodium ions, which enhance its solubility and stability in aqueous solutions.

CAT: BRP-00680

MF: C10H16N5O11P3S2 (free acid)

MF: 539.31 (free acid)

Purity: >98%

Description: 3'-O-Allyl-ATP Sodium Salt is a derivative of adenosine triphosphate (ATP) with an allyl group attached to the 3'-hydroxyl position of the ribose sugar moiety. It is commonly used in enzymatic reactions, where the allyl group can serve as a site for chemical modification or conjugation to various molecules or surfaces. The sodium salt form enhances its solubility and stability, making it suitable for biochemical applications such as enzymology studies, kinase assays, and protein labeling.

CAT: BRP-00681

MF: C13H20N5O13P3 (free acid)

MF: 547.25 (free acid)

Purity: >95%

Description: 5-Aminopropargyl UTP Sodium Salt is a derivative of uridine triphosphate (UTP) with an aminopropargyl group attached to the 5-position of the uracil base. It is utilized in enzymatic reactions for RNA synthesis, particularly in the incorporation of modified nucleotides into RNA molecules. The sodium salt form ensures its solubility and stability, facilitating its use in various molecular biology techniques such as RNA labeling, click chemistry-based conjugation, and RNA-protein interaction studies.

CAT: BRP-00682

MF: C12H18N3O15P3 (free acid)

MF: 537.20 (free acid)

Purity: >98%

Description: 3'-O-Allyl-GTP Sodium Salt is a derivative of guanosine triphosphate (GTP) with an allyl group attached to the 3'-hydroxyl position of the ribose sugar moiety. It finds application in enzymatic reactions, where the allyl group allows for site-specific chemical modifications or conjugation to various molecules or surfaces. The sodium salt form improves its solubility and stability, making it suitable for biochemical research, including GTP-dependent processes such as signal transduction, RNA synthesis, and protein translation.

CAT: BRP-00683

MF: C13H20N5O14P3 (free acid)

MF: 563.25 (free acid)

Purity: >95%

Description: 3'-O-Allyl-CTP Sodium Salt is a derivative of cytidine triphosphate (CTP) with an allyl group attached to the 3'-hydroxyl position of the ribose sugar moiety. It is employed in enzymatic reactions, where the allyl group serves as a site for chemical modification or conjugation to various molecules or surfaces. The sodium salt form enhances its solubility and stability, making it suitable for applications such as RNA labeling, RNA-protein crosslinking, and RNA structural studies.

CAT: BRP-00684

MF: C12H20N3O14P3 (free acid)

MF: 523.22 (free acid)

Purity: >95%

Description: 3'-O-Allyl-UTP Sodium Salt is a derivative of uridine triphosphate (UTP) with an allyl group attached to the 3'-hydroxyl position of the ribose sugar moiety. It is commonly used in enzymatic reactions, where the allyl group allows for site-specific chemical modifications or conjugation to various molecules or surfaces. The sodium salt form improves its solubility and stability, making it suitable for applications such as RNA labeling, RNA-protein crosslinking, and RNA structural studies.

CAT: BRP-00685

MF: C12H19N2O15P3 (free acid)

MF: 524.20 (free acid)

Purity: >95%

Description: 5-hme-UTP sodium salt, the cutting-edge solution widely applied in biomedicine to scrutinize RNA, is a remarkable discovery. This chemically modified uridine triphosphate profoundly enriches RNA, rendering it selectively detectable. Expeditions using 5-hme-UTP have evinced its dendritic distribution, unveiling molecular sequences implicated in sundry ailments like cancer and neurodegenerative diseases. Hence, 5-hme-UTP has emerged as a pivotal tool to dissect RNA patterns and unravel the indelible complexities of life.

CAT: BRP-00686

MF: C10H17N2O16P3 (free acid)

MF: 514.17 (free acid)

Purity: >98%