Cemdisiran - CAS 1639264-46-2

Catalog number: BRP-02069

Cemdisiran

Cemdisiran is an N-acetylgalactosamine (GalNAc) conjugated siRNA for the treatment of complement-mediated diseases by suppressing liver production of complement 5 (C5) protein.

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.
Catalog
BRP-02069
Synonyms
ALN-CC5; RNA, (Am-sp-Am-sp-(2'-deoxy-2'-fluoro)G-Cm-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)G-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)U-Um-Um-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)A-Am-Um-Am), 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-Um-Am-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Am-Um-Am-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)G-Cm-Um-Um-sp-Um-sp-Um-dT-dT) (1:1); siRNA ALN-CC5; Small interfering RNA ALN CC5; Small interfering RNA Cemdisiran
CAS
1639264-46-2
Molecular Weight
16782.53
Molecular Formula
C542H711F17N169O330P45S6
Solubility
Soluble in Water
Appearance
White to off-white solid
Storage
Store at 2-8 °C, sealed storage, away from moisture
Sequence
RNA, (uauuauaaaaauaucuugcuuuutt), complex with RNA (aagcaagauauuuuuauaaua) (1:1)
Related Products
Online Inquiry
Verification code
Inquiry Basket