Bn-dU CEP

Bn-dU CEP is a modified phosphoramidite used in oligonucleotide synthesis. It features a benzylcarbamoyl group attached to the 5-position of the 2'-deoxyuridine (dU) base, and is equipped with a cyanoethyl (CE) protecting group on the phosphoramidite moiety. This modification allows for the incorporation of the benzylcarbamoyl group into synthetic DNA sequences, potentially altering the properties of the resulting oligonucleotides for specific biochemical and biophysical applications.

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Catalog

BRP-02197

Synonyms

Bn-Du Phosphoramidite; 5-(Benzylcarbamoyl)-dU CE-Phosphoramidite; 5-(Benzylcarbamoyl)-2'-deoxy-dU CE-Phosphoramidite; Bn-dU 3'-CE-Phosphoramidite

IUPAC Name

(2R,3S,5R)-5-(5-(benzylcarbamoyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

Molecular Weight

863.95

Molecular Formula

C47H54N5O9P

InChI

InChI=1S/C47H54N5O9P/c1-32(2)52(33(3)4)62(59-27-13-26-48)61-41-28-43(51-30-40(45(54)50-46(51)55)44(53)49-29-34-14-9-7-10-15-34)60-42(41)31-58-47(35-16-11-8-12-17-35,36-18-22-38(56-5)23-19-36)37-20-24-39(57-6)25-21-37/h7-12,14-25,30,32-33,41-43H,13,27-29,31H2,1-6H3,(H,49,53)(H,50,54,55)/t41-,42+,43+,62?/m0/s1

InChIKey

IBKSJCLOSMZOIH-PJQDADNVSA-N

Purity

≥95%

Storage

Store at -20 °C

Chemical Structure: