5'-DMT-dG(DMF)-3'-Q Linker-CPG; 1000 Å

Catalog number: BRL-032

5'-DMT-dG (DMF)-3'-Q linker-CPG is used to add unmodified dG to the 3' end of oligonucleotides.

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Appearance

White powder

Storage

+2 to +8 °C.

Shipping

Room temperature.

Synthesis Conditions

Synthesis can be performed on these supports according to standard procedures with deprotection and cleavage modifications noted.

Cleavage Conditions

Cleavage can be carried out in 2 minutes at room temperature using concentrated NH4OH.

Deprotection Conditions

If fast deprotecting amidites are used; deprotection can be carried out using concentrated NH4OH for 1 hour at 60°C.

Chemical Structure:

Reference Reading

1. Mercury bis(phenyltellurolate) as a precursor for the synthesis of binary and ternary nanoclusters

Davi F Back, Gelson N M de Oliveira, Robert A Burrow, Ernesto E Castellano, Ulrich Abram, Ernesto S Lang. Inorg Chem. 2007 Apr 2;46(7):2356-8. doi: 10.1021/ic070006q.

The reaction of Hg(TePh)2 with AgX (X = Cl, NO3) in the presence of PPh3 and PMePh2 in dimethylformamide (DMF) affords the cluster [Hg6Ag4(TePh)16] (1) at room temperature or [Hg6Ag4Te(TePh)14]2 (2) with heating. When Hg(TePh)2 is reacted with [Co(PPh3)2Cl2] or [Ni(PPh3)2Cl2], the clusters [Hg8Te(PhTe)12Cl4]Q [3; Q = [Co(DMF)6]2+ (3a), [Ni(DMF)6]2+ (3b)] are formed. The syntheses of 1 and 2 occur with the incorporation of AgI into the cluster, and the single-crystal analyses show that the two ternary clusters consist of Hg, Ag, and Te centers occupying well-defined positions. Compounds 3a and 3b do not show the incorporation of the metal into the cluster, but the CoII and NiII salts provide the Cl atom to generate the anionic cluster 3 stabilized by the [Co(DMF)6]2+ or [Ni(DMF)6]2+ ion.