Description: 2'-tBDSilyl Guanosine (N-PAC) 3'-lcaa CPG 500Å is a specialized nucleotide used in oligonucleotide synthesis, particularly for solid-phase synthesis. This compound comprises a guanosine nucleoside with a 2'-tert-butyldimethylsilyl (tBDSilyl) group protecting the 2'-hydroxyl position. Additionally, it features a phenoxyacetyl (PAC) group attached to the amine group of the guanosine base. Moreover, it has a linker (lcaa) at the 3' end, and it is synthesized on a Controlled Pore Glass (CPG) support with a pore size of 500 angstroms. This compound facilitates controlled addition during oligonucleotide synthesis, enabling precise customization and design of guanosine-modified oligonucleotides for various molecular biology applications, including RNA interference (RNAi) studies, gene expression analysis, and antisense oligonucleotide design.
CAT: BRP-01472