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CPGs for Oligo Synthesis

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5'-DMT-dA(Bz)-Suc-CPG; 500 Å (BRP-02263)

Description: 5'-DMT-dA(Bz)-Suc-CPG is used for incorporating unmodified dA at the 3' end of an oligonucleotide.
CAT: BRP-02263
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.
Deprotection Conditions: When using fast deprotecting amidites (e.g., C-Ac; G-DMF; G-PAC), please use concentrated ammonia for 1h or AMA for 30 min at 60°C. When using standard amidites (e.g., C-Bz; G-iBu), please use concentrated ammonia for 5h at 60°C.
Synonyms: 5'-DMT-dA(Bz) CPG; 500 Å; 5'-O-DMT-2'-deoxy-A(Bz)-3'-O-Suc-CPG; 500 Å

5'-DMT-dA(Bz)-Suc-CPG; 500 Å (High Load) (BRP-02264)

Description: 5'-DMT-dA(Bz)-Suc-CPG is used for incorporating unmodified dA at the 3' end of an oligonucleotide.
CAT: BRP-02264
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.
Deprotection Conditions: When using fast deprotection amidites (such as C-Ac; G-DMF), use concentrated ammonia at 60°C for 1h or AMA for 30 min. When using standard amidites (such as C-Bz; G-iBu), please use concentrated ammonia at 60°C for 5h.
Synonyms: 5'-DMT-dA(Bz) CPG; 500 Å (High Load); 5'-O-DMT-2'-deoxy-A(Bz)-3'-O-Suc-CPG; 500 Å (High Load)

5'-DMT-dC(Ac)-3'-Q Linker-CPG; 1000 Å (BRP-02265)

Description: 5'-DMT-dC(Ac)-3'-Q Linker-CPG; 1000 Å is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating acetyl-protected deoxycytidine (dC) residues. It includes a 5'-DMT (dimethoxytrityl) protective group for the 5' end of the deoxycytidine base, an acetyl group (Ac) to protect the cytidine’s exocyclic amino group, and a 3'-Q (quencher) linker attached to controlled pore glass (CPG) with a 1000 Å pore size. The 3'-Q linker is used for fluorescence-based applications, where it can act as a quencher to suppress fluorescence from a nearby fluorophore. This reagent ensures precise incorporation of deoxycytidine while facilitating efficient synthesis and fluorescence quenching.
CAT: BRP-02265
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Synthesis Conditions: Synthesis can be performed on these supports according to standard procedures with deprotection and cleavage modifications noted.
Cleavage Conditions: Cleavage can be carried out in 2 minutes at room temperature using concentrated NH4OH.
Deprotection Conditions: If fast deprotecting amidites are used; deprotection can be carried out using concentrated NH4OH for 1 hour at 60°C.
Synonyms: 5'-O-DMT-2'-deoxy-C(Ac)-3'-O-Q Linker-CPG; 1000 Å

5'-DMT-dC(Ac)-Suc-CPG; 1000 Å (BRP-02266)

Description: 5'-DMT-dC(Ac)-Suc-CPG; 1000 Å is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating acetyl-protected deoxycytidine (dC) residues. It features a 5'-DMT (dimethoxytrityl) protective group to protect the 5' end of the deoxycytidine base, an acetyl group (Ac) to protect the cytidine's exocyclic amino group, and a succinyl (Suc) linker attached to controlled pore glass (CPG) with a 1000 Å pore size. This configuration allows for efficient synthesis and high loading capacity, facilitating precise incorporation of deoxycytidine into DNA sequences while maintaining stability and ease of deprotection.
CAT: BRP-02266
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at -20 °C
Shipping: Cold.
Cleavage Conditions: Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.
Deprotection Conditions: When using fast deprotection amidites (such as C-Ac; G-DMF), use concentrated ammonia at 60°C for 1h or AMA for 30 min. When using standard amidites (such as C-Bz; G-iBu), please use concentrated ammonia at 60°C for 5h.
Synonyms: 5'-DMT-dC(Ac)-CPG; 1000 Å; 5'-O-DMT-2'-deoxy-C(Ac)-3'-O-Suc-CPG; 1000 Å

5'-DMT-dC(Ac)-Suc-CPG; 1400 Å (BRP-02267)

Description: 5'-DMT-dC(Ac)-Suc-CPG; 1400 Å is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating acetyl-protected deoxycytidine (dC) residues. It features a 5'-DMT (dimethoxytrityl) protective group to protect the 5' end of the deoxycytidine base, an acetyl group (Ac) to protect the cytidine's exocyclic amino group, and a succinyl (Suc) linker attached to controlled pore glass (CPG) with a 1400 Å pore size. This configuration allows for efficient synthesis and high loading capacity, facilitating precise incorporation of deoxycytidine into DNA sequences while maintaining stability and ease of deprotection.
CAT: BRP-02267
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.
Deprotection Conditions: When using fast deprotection amidites (such as C-Ac; G-DMF), use concentrated ammonia at 60°C for 1h or AMA for 30 min. When using standard amidites (such as C-Bz; G-iBu), please use concentrated ammonia at 60°C for 5h.
Synonyms: 5'-DMT-dC(Ac)-CPG; 1400 Å; 5'-O-DMT-2'-deoxy-C(Ac)-3'-O-Suc-CPG; 1400 Å

5'-DMT-dC(Ac)-Suc-CPG; 2000 Å (BRP-02268)

Description: 5'-DMT-dC(Ac)-Suc-CPG; 2000 Å is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating acetyl-protected deoxycytidine (dC) residues. It features a 5'-DMT (dimethoxytrityl) protective group to protect the 5' end of the deoxycytidine base, an acetyl group (Ac) to protect the cytidine's exocyclic amino group, and a succinyl (Suc) linker attached to controlled pore glass (CPG) with a 2000 Å pore size. This configuration allows for efficient synthesis and high loading capacity, facilitating precise incorporation of deoxycytidine into DNA sequences while maintaining stability and ease of deprotection.
CAT: BRP-02268
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.
Deprotection Conditions: When using fast deprotection amidites (such as C-Ac; G-DMF), use concentrated ammonia at 60°C for 1h or AMA for 30 min. When using standard amidites (such as C-Bz; G-iBu), please use concentrated ammonia at 60°C for 5h.
Synonyms: 5'-DMT-dC(Ac)-CPG; 2000 Å; 5'-O-DMT-2'-deoxy-C(Ac)-3'-O-Suc-CPG; 2000 Å

5'-DMT-dC(Ac)-Suc-CPG; 500 Å (BRP-02269)

Description: 5'-DMT-dC(Ac)-Suc-CPG; 500 Å is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating acetyl-protected deoxycytidine (dC) residues. It features a 5'-DMT (dimethoxytrityl) protective group to protect the 5' end of the deoxycytidine base, an acetyl group (Ac) to protect the cytidine's exocyclic amino group, and a succinyl (Suc) linker attached to controlled pore glass (CPG) with a 500 Å pore size. This configuration allows for efficient synthesis and high loading capacity, facilitating precise incorporation of deoxycytidine into DNA sequences while maintaining stability and ease of deprotection.
CAT: BRP-02269
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.
Deprotection Conditions: When using fast deprotecting amidites (e.g., C-Ac; G-DMF; G-PAC), please use concentrated ammonia for 1h or AMA for 30 min at 60°C. When using standard amidites (e.g., C-Bz; G-iBu), please use concentrated ammonia for 5h at 60°C.
Synonyms: 5'-DMT-dC(Ac)-CPG; 500 Å; 5'-O-DMT-2'-deoxy-C(Ac)-3'-O-Suc-CPG; 500 Å

5'-DMT-dC(Ac)-Suc-CPG; 500 Å (High Load) (BRP-02270)

Description: 5'-DMT-dC(Ac)-Suc-CPG; 500 Å (High Load) is a reagent used in the solid-phase synthesis of oligonucleotides for incorporating acetyl-protected deoxycytidine (dC) residues. It features a 5'-DMT (dimethoxytrityl) protective group for the 5' end, an acetyl group (Ac) to protect the cytidine’s exocyclic amino group, and a succinyl (Suc) linker attached to controlled pore glass (CPG) with a 500 Å pore size. The "High Load" designation indicates a higher capacity for nucleoside attachment, allowing for efficient synthesis of oligonucleotides with a high degree of loading and precise incorporation of deoxycytidine.
CAT: BRP-02270
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.
Deprotection Conditions: When using fast deprotection amidites (such as C-Ac; G-DMF), use concentrated ammonia at 60°C for 1h or AMA for 30 min. When using standard amidites (such as C-Bz; G-iBu), please use concentrated ammonia at 60°C for 5h.
Synonyms: 5'-DMT-dC(Ac)-CPG; 500 Å (High Load); 5'-O-DMT-2'-deoxy-C(Ac)-3'-O-Suc-CPG; 500 Å (High Load)

5'-DMT-dC(Bz)-Suc-CPG; 1000 Å (BRP-02271)

Description: 5'-DMT-dC(Bz)-Suc-CPG is used to add unmodified dC to the 3' end of the oligonucleotide.
CAT: BRP-02271
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Cleave in concentrated ammonia for 90 minutes at 25°C.
Deprotection Conditions: Deprotect in concentrated ammonia for 5 hours at 60°C.
Synonyms: 5'-O-DMT-2'-deoxy-C(Bz)-3'-O-Suc-CPG; 1000 Å

5'-DMT-dC(Bz)-Suc-CPG; 1400 Å (BRP-02272)

Description: 5'-DMT-dC(Bz)-Suc-CPG is used to add unmodified dC to the 3' end of the oligonucleotide.
CAT: BRP-02272
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Cleave in concentrated ammonia for 90 minutes at 25°C.
Deprotection Conditions: Deprotect in concentrated ammonia for 5 hours at 60°C.
Synonyms: 5'-O-DMT-2'-deoxy-C(Bz)-3'-O-Suc-CPG; 1400 Å

5'-DMT-dC(Bz)-Suc-CPG; 500 Å (BRP-02273)

Description: 5'-DMT-dC(Bz)-Suc-CPG is used to add unmodified dC to the 3' end of the oligonucleotide.
CAT: BRP-02273
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Cleave in concentrated ammonia for 90 minutes at 25°C.
Deprotection Conditions: Deprotect in concentrated ammonia for 5 hours at 60°C.
Synonyms: 5'-O-DMT-2'-deoxy-C(Bz)-3'-O-Suc-CPG; 500 Å

5'-DMT-dG(DMF)-3'-Q Linker-CPG; 1000 Å (BRP-02274)

Description: 5'-DMT-dG (DMF)-3'-Q linker-CPG is used to add unmodified dG to the 3' end of oligonucleotides.
CAT: BRP-02274
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Synthesis Conditions: Synthesis can be performed on these supports according to standard procedures with deprotection and cleavage modifications noted.
Cleavage Conditions: Cleavage can be carried out in 2 minutes at room temperature using concentrated NH4OH.
Deprotection Conditions: If fast deprotecting amidites are used; deprotection can be carried out using concentrated NH4OH for 1 hour at 60°C.
Synonyms: 5'-O-DMT-2'-deoxy-G(DMF)-3'-O-Q Linker-CPG; 1000 Å

5'-DMT-dG(DMF)-Suc-CPG; 1000 Å (BRP-02275)

Description: 5'-DMT-dG(DMF)-Suc-CPG is used to add unmodified dG to the 3' end of oligonucleotides.
CAT: BRP-02275
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.
Deprotection Conditions: When using fast deprotecting amidites (e.g., C-Ac; G-DMF; G-PAC), please use concentrated ammonia for 1h or AMA for 30 min at 60°C. When using standard amidites (e.g., C-Bz; G-iBu), please use concentrated ammonia for 5h at 60°C.
Synonyms: 5'-DMT-dG(DMF)-CPG; 1000 Å; 5'-O-DMT-2'-deoxy-G(DMF)-3'-O-Suc-CPG; 1000 Å

5'-DMT-dG(DMF)-Suc-CPG; 500 Å (BRP-02276)

Description: 5'-DMT-dG(DMF)-Suc-CPG is used to add unmodified dG to the 3' end of oligonucleotides.
CAT: BRP-02276
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.
Deprotection Conditions: When using fast deprotecting amidites (e.g., C-Ac; G-DMF; G-PAC), please use concentrated ammonia for 1h or AMA for 30 min at 60°C. When using standard amidites (e.g., C-Bz; G-iBu), please use concentrated ammonia for 5h at 60°C.
Synonyms: 5'-DMT-dG(DMF)-CPG; 500 Å; 5'-O-DMT-2'-deoxy-G(DMF)-3'-O-Suc-CPG; 500 Å

5'-DMT-dG(DMF)-Suc-CPG; 500 Å (High Load) (BRP-02277)

Description: 5'-DMT-dG(DMF)-Suc-CPG is used to add unmodified dG to the 3' end of oligonucleotides.
CAT: BRP-02277
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.
Deprotection Conditions: When using fast deprotecting amidites (e.g., C-Ac; G-DMF) use concentrated ammonia for 1 hour or AMA for 30 minutes at 60°C. When using standard amidites (e.g., C-Bz; G-iBu) use concentrated ammonia for 5 hours at 60°C.
Synonyms: 5'-DMT-dG(DMF)-CPG; 500 Å (High Load); 5'-O-DMT-2'-deoxy-G(DMF)-3'-O-Suc-CPG; 500 Å (High Load)

5'-DMT-dG(iBu)-Suc-CPG; 1000 Å (BRP-02278)

Description: 5'-DMT-dG(iBu)-Suc-CPG is used to add unmodified dG to the 3' end of oligonucleotides.
CAT: BRP-02278
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 30 minutes at 65°C when using standard amidites.
Deprotection Conditions: When using standard amidites (eg. C-Bz; G-iBu) use concentrated ammonia for 5 hours at 65°C.
Synonyms: 5'-DMT-dG(iBu)-CPG; 1000 Å; 5'-O-DMT-2'-deoxy-G(iBu)-3'-O-Suc-CPG; 1000 Å

5'-DMT-dG(iBu)-Suc-CPG; 1400 Å (BRP-02279)

Description: 5'-DMT-dG(iBu)-Suc-CPG is used to add unmodified dG to the 3' end of oligonucleotides.
CAT: BRP-02279
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 30 minutes at 65°C when using standard amidites.
Deprotection Conditions: When using standard amidites (eg. C-Bz; G-iBu) use concentrated ammonia for 5 hours at 65°C.
Synonyms: 5'-DMT-dG(iBu)-CPG; 1400 Å; 5'-O-DMT-2'-deoxy-G(iBu)-3'-O-Suc-CPG; 1400 Å

5'-DMT-dG(iBu)-Suc-CPG; 2000 Å (BRP-02280)

Description: 5'-DMT-dG(iBu)-Suc-CPG is used to add unmodified dG to the 3' end of oligonucleotides.
CAT: BRP-02280
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 30 minutes at 65°C when using standard amidites.
Deprotection Conditions: When using standard amidites (eg. C-Bz; G-iBu) use concentrated ammonia for 5 hours at 65°C.
Synonyms: 5'-DMT-dG(iBu)-CPG; 2000 Å; 5'-O-DMT-2'-deoxy-G(iBu)-3'-O-Suc-CPG; 2000 Å

5'-DMT-dG(iBu)-Suc-CPG; 500 Å (BRP-02281)

Description: 5'-DMT-dG(iBu)-Suc-CPG is used to add unmodified dG to the 3' end of oligonucleotides.
CAT: BRP-02281
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 30 minutes at 65°C when using standard amidites.
Deprotection Conditions: When using standard amidites (eg. C-Bz; G-iBu) use concentrated ammonia for 5 hours at 65°C.
Synonyms: 5'-DMT-dG(iBu)-CPG; 500 Å; 5'-O-DMT-2'-deoxy-G(iBu)-3'-O-Suc-CPG; 500 Å

5'-DMT-dI-Suc-CPG (deoxyInosine CPG); 1000 Å (BRP-02282)

Description: 5'-DMT-dI-Suc-CPG is used to incorporate deoxyinosine base at the 3' end of oligonucleotides.
CAT: BRP-02282
Appearance: White powder
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at 2-8 °C
Shipping: Room temperature.
Cleavage Conditions: Use concentrated ammonia for 90 min at 25°C or 30 min at 60°C, or 1:1 ammonia:methylamine (AMA) for 25 min at 25°C when using fast deprotecting amidites.
Deprotection Conditions: When using fast deprotection amidites (such as C-Ac; G-DMF), use concentrated ammonia at 60°C for 1h or AMA for 30 min. When using standard amidites (such as C-Bz; G-iBu), please use concentrated ammonia at 60°C for 5h.
Synonyms: 5'-DMT-dI-Suc-CPG; 1000 Å; DeoxyInosine CPG; 1000 Å; 5'-O-DMT-2'-deoxy-I-3'-O-Suc-CPG; 1000 Å

Frequently Asked Questions (FAQ)

What pore size CPG is recommended for long oligonucleotide synthesis?

For long DNA or RNA sequences, 1000 Å or 2000 Å CPG is generally recommended to improve reagent diffusion and maintain coupling efficiency during extended synthesis cycles.

How does loading capacity affect CDMO manufacturing projects?

Loading capacity influences both yield and coupling efficiency. Controlled and reproducible loading is essential for minimizing batch-to-batch variability in long-term manufacturing programs.

Do you provide COA and batch traceability?

Each batch is supplied with a Certificate of Analysis (COA) and full traceability to support audits and quality reviews.

Can you support material supply during process scale-up?

Yes. We support material supply from early process development through scale-up and routine manufacturing.

How should CPGs be stored?

CPGs should be stored in a dry, tightly sealed container at room temperature to maintain surface functionality and consistent performance.

* Only for research. Not suitable for any diagnostic or therapeutic use.

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