CPGs for Oligo Synthesis

Description: 2'-tBDSilyl Guanosine (N-ibu) 3'-lcaa CPG 1000Å is a specialized nucleotide compound utilized in solid-phase oligonucleotide synthesis. It comprises a guanosine nucleoside modified with a 2'-tert-butyldimethylsilyl (tBDSilyl) group at the 2'-position, which protects the hydroxyl group. Additionally, it features an isobutyryl (ibu) group attached to the amine group of the guanosine base, providing additional protection. At the 3'-end, there is a long-chain alkylamine (lcaa) linker, facilitating attachment to a Controlled Pore Glass (CPG) support matrix with a pore size of 1000 angstroms. This compound enables controlled addition during oligonucleotide synthesis, enabling precise customization and design of guanosine-modified oligonucleotides for various molecular biology applications.

CAT: BRP-01479

Description: 2'-tBDSilyl Uridine 3'-lcaa CPG 1000Å is a specialized nucleotide used in solid-phase oligonucleotide synthesis. It consists of a uridine nucleoside modified with a 2'-tert-butyldimethylsilyl (tBDSilyl) group at the 2'-position to protect the hydroxyl group. Additionally, it features a long-chain alkylamine (lcaa) linker at the 3' position, facilitating attachment to a Controlled Pore Glass (CPG) support matrix with a pore size of 1000 angstroms. This compound enables controlled addition during oligonucleotide synthesis, allowing for precise customization and design of uridine-modified oligonucleotides for various molecular biology applications.

CAT: BRP-01480

Description: DMT-C6 Disulfide lcaa CPG 500Å refers to a specialized support matrix used in solid-phase oligonucleotide synthesis. This compound features a long-chain alkylamine (lcaa) linker and is immobilized on Controlled Pore Glass (CPG) with a pore size of 500 angstroms. The support is functionalized with a DMT-C6 disulfide moiety, which allows for the attachment of thiol-containing molecules. This support matrix is particularly useful for the synthesis of oligonucleotides with disulfide modifications, enabling applications such as conjugation to thiol-reactive compounds or surface immobilization in various molecular biology and biotechnology research contexts.

CAT: BRP-01481

Description: 3'-TOM-ribo Uridine 2'-lcaa CPG 1000Å is a specialized nucleotide compound utilized in solid-phase oligonucleotide synthesis. It consists of a ribonucleoside with a 3'-TOM (3'-O-tom)-ribo modification, where a TOM (triisopropylsilyl oxy methyl) group is attached to the 3'-hydroxyl of the ribose sugar. Additionally, it features a long-chain alkylamine (lcaa) linker at the 2'-position, facilitating attachment to a Controlled Pore Glass (CPG) support matrix with a pore size of 1000 angstroms. This compound enables controlled addition during oligonucleotide synthesis, allowing for precise customization and design of uridine-modified ribonucleotides for various molecular biology applications.

CAT: BRP-01482

Description: 3'-TOM-ribo Adenosine (N-acetyl) 2'-lcaa CPG 500Å is a specialized nucleotide compound used in solid-phase oligonucleotide synthesis. It comprises a ribonucleoside with a 3'-TOM (3'-O-tom)-ribo modification, where TOM (triisopropylsilyl oxy methyl) group is attached to the 3'-hydroxyl of the ribose sugar. Additionally, an acetyl (Ac) group is attached to the amine group of the adenosine base. Moreover, it features a long-chain alkylamine (lcaa) linker at the 2'-position, facilitating attachment to a Controlled Pore Glass (CPG) support matrix with a pore size of 500 angstroms. This compound enables controlled addition during oligonucleotide synthesis, allowing for precise customization and design of adenosine-modified ribonucleotides for various molecular biology applications.

CAT: BRP-01483

Description: 3'-TOM-ribo Cytidine (N-acetyl) 2'-lcaa CPG 500Å is a specialized nucleotide used in solid-phase oligonucleotide synthesis. It comprises a ribonucleoside with a 3'-TOM (3'-O-tom)-ribo modification, where a TOM (triisopropylsilyl oxy methyl) group is attached to the 3'-hydroxyl of the ribose sugar. Additionally, an acetyl (Ac) group is attached to the amine group of the cytidine base. Moreover, it features a long-chain alkylamine (lcaa) linker at the 2'-position, facilitating attachment to a Controlled Pore Glass (CPG) support matrix with a pore size of 500 angstroms. This compound enables controlled addition during oligonucleotide synthesis, allowing for precise customization and design of cytidine-modified ribonucleotides for various molecular biology applications.

CAT: BRP-01484

Description: 2'-TOM-ribo Guanosine (N-acetyl) 3'-lcaa CPG 500Å is a specialized nucleotide used in solid-phase oligonucleotide synthesis. It comprises a ribonucleoside with a 2'-TOM (2'-O-tom)-ribo modification, where a TOM (triisopropylsilyl oxy methyl) group is attached to the 2'-hydroxyl of the ribose sugar. Additionally, an acetyl (Ac) group is attached to the amine group of the guanosine base. Furthermore, it contains a long-chain alkylamine (lcaa) linker at the 3' position, facilitating attachment to a Controlled Pore Glass (CPG) support matrix with a pore size of 500 angstroms. This compound enables controlled addition during oligonucleotide synthesis, allowing for precise customization and design of guanosine-modified ribonucleotides for various molecular biology applications.

CAT: BRP-01485

Description: Universal UnyLinker Support 1000Å is a versatile solid-phase support used in oligonucleotide synthesis. It features a Universal UnyLinker, a cleavable linker that allows for the efficient release of synthesized oligonucleotides from the solid support. The support is based on a Controlled Pore Glass (CPG) matrix with a pore size of 1000 angstroms, which provides ample surface area for high-efficiency synthesis. This support is compatible with various oligonucleotide sequences and modifications, making it an ideal choice for a wide range of molecular biology and biotechnology applications.

CAT: BRP-01486

Description: Universal UnyLinker Support Polystyrene 300Å is a versatile solid-phase support used in oligonucleotide synthesis. It features a Universal UnyLinker, which is a cleavable linker allowing the efficient release of synthesized oligonucleotides from the solid support. The support is based on polystyrene with a pore size of 300 angstroms, providing a robust and chemically stable matrix. This support is compatible with various oligonucleotide sequences and modifications, making it an ideal choice for diverse molecular biology and biotechnology applications.

CAT: BRP-01487

Description: 2'-Fluoro Guanosine (n-ibu)-3'-succinyl lcaa CPG 1000Å is a modified nucleoside attached to a controlled pore glass (CPG) solid support with a pore size of 1000 angstroms. This compound features a 2'-fluoro modification and an N2-isobutyryl (n-ibu) protecting group. The 3'-end is linked via a succinyl linker to the long chain alkylamine (lcaa) CPG, which is commonly used in automated DNA and RNA synthesis. This specific modification enhances the stability and binding properties of synthesized oligonucleotides, making it valuable for research and therapeutic applications.

CAT: BRP-01600

Description: 2'-Fluoro Cytidine 3'-lcaa CPG 500Å is a modified nucleoside attached to a controlled pore glass (CPG) solid support with a pore size of 500 angstroms. The 2'-fluoro modification enhances the stability of nucleic acids by increasing resistance to enzymatic degradation. The 3'-end is linked via a long chain alkylamine (lcaa) linker to the CPG support, which is used in automated DNA and RNA synthesis. This modification is particularly useful in research and therapeutic applications where enhanced nucleic acid stability and binding properties are desired.

CAT: BRP-01601

Description: 2'-Fluoro Guanosine (N,N-DMF) 3'-lcaa CPG 500Å is a modified nucleoside attached to a controlled pore glass (CPG) solid support with a pore size of 500 angstroms. This compound features a 2'-fluoro modification, enhancing stability and resistance to enzymatic degradation. The guanosine is also protected with an N,N-dimethylformamidine (DMF) group. The 3'-end is linked to a long chain alkylamine (lcaa) CPG support, facilitating its use in automated DNA and RNA synthesis. This combination of modifications improves the stability and binding properties of the synthesized oligonucleotides, making it valuable for research and therapeutic applications.

CAT: BRP-01602

Description: 2'-Fluoro Adenosine (N-Bz) 3'-lcaa CPG 1000Å is a modified nucleoside attached to a controlled pore glass (CPG) solid support with a pore size of 1000 angstroms. It features a 2'-fluoro modification, which enhances the stability of nucleic acids by increasing resistance to enzymatic degradation. The adenosine is protected with an N-benzoyl (N-Bz) group. The 3'-end is linked to a long chain alkylamine (lcaa) CPG support, which is suitable for automated DNA and RNA synthesis. This specific configuration improves the stability and binding properties of the synthesized oligonucleotides, making it beneficial for research and therapeutic applications.

CAT: BRP-01603

Description: 2'-Fluoro Adenosine (N,N-DMF) 3'-lcaa CPG 1000Å is a modified nucleoside attached to a controlled pore glass (CPG) solid support with a pore size of 1000 angstroms. This compound includes a 2'-fluoro modification, enhancing the stability and resistance of nucleic acids to enzymatic degradation. The adenosine is protected with an N,N-dimethylformamidine (DMF) group. The 3'-end is attached to a long chain alkylamine (lcaa) CPG support, facilitating its use in automated DNA and RNA synthesis. This specific modification improves the stability, binding properties, and overall performance of the synthesized oligonucleotides, making it valuable for research and therapeutic applications.

CAT: BRP-01604

Description: 2'-Fluoro Uridine 3'-lcaa CPG 1000Å is a modified nucleoside attached to a controlled pore glass (CPG) solid support with a pore size of 1000 angstroms. It features a 2'-fluoro modification, which enhances the stability of the nucleic acid by increasing resistance to enzymatic degradation. The 3'-end of the nucleoside is linked to a long chain alkylamine (lcaa) CPG support, making it suitable for automated DNA and RNA synthesis. This combination of modifications enhances the stability and binding properties of the synthesized oligonucleotides, making it valuable for various research and therapeutic applications.

CAT: BRP-01605

Description: 2'-Methyl-guanosine-(iBu)-succinyl-CPG is a crucial biomedicine product used for solid-phase synthesis of oligonucleotides. It serves as a key building block for the chemical synthesis of modified nucleic acids. With its unique succinyl modification, this CPG derivative enables efficient incorporation into oligonucleotides for pharmaceutical research and diagnostic applications related to drug screening, target identification, and disease detection.

CAT: BRP-01696

Description: 2'-Methyl-cytidine-(Bz)-succinyl-CPG, an essential entity within the biomedicine realm, serves as a pivotal tool in the intricate process of synthesizing nucleic acids and diverse oligonucleotides. Its significance arises from its multifaceted applicability in drug discovery investigations, specifically focusing on the advancement of antiviral and anticancer medications.

CAT: BRP-01697

Description: 2'-Methyl-adenosine-(benzoyl)-succinyl-CPG, a highly versatile and pivotal biomedical entity, finds widespread utilization in the realm of pharmaceutical exploration and advancement. This distinctive compound assumes a critical role as an indispensable cornerstone for the synthesis of oligonucleotides and nucleic acid analogs, fostering a promising avenue for combatting an array of diseases such as cancer and viral infections.

CAT: BRP-01698

Appearance: Off-white solid

Description: 3'-Spacer C3 CPG can act as a blocker of exonuclease and polymerase activity at the 3' terminal. dSpacer is used to introduce stable racemic sites in oligonucleotides. PC Spacer is a photocracking C3 spacer modifier. Spacer phosphamides C3, C9, C12, and C18 are used to insert spacer arms in oligonucleotides, and these compounds can be added multiple times when longer spacer arms are needed.

CAT: BRP-02241

Appearance: White to off-white powder

Description: 2'-O-Methyl-A(Bz)-Suc-CPG; 500 Å is a reagent used in the solid-phase synthesis of RNA oligonucleotides, specifically for incorporating 2'-O-methyladenosine residues. It includes a benzoyl-protected adenine base and a succinyl linker that attaches the nucleoside to controlled pore glass (CPG) with a pore size of 500 Å. The 2'-O-methyl modification enhances the stability and resistance to degradation of the RNA, making this reagent ideal for the synthesis of RNA oligonucleotides with improved properties.

CAT: BRP-02242

Appearance: White powder