CPGs for Oligo Synthesis

Description: 6-FAM Glyceryl Support CPG 500Å is a controlled pore glass (CPG) with a pore size of 500 angstroms, functionalized with a glyceryl linker and 6-carboxyfluorescein (6-FAM). This support material is used for synthesizing oligonucleotides that are fluorescently labeled with 6-FAM, facilitating applications in molecular biology such as fluorescence-based detection, quantitative PCR (qPCR), and fluorescence resonance energy transfer (FRET) assays. The glyceryl linker ensures efficient attachment of the fluorophore to the oligonucleotide, providing strong and reliable fluorescence signals.

CAT: BRP-01364

Description: DMT-5-FAM lcaa CPG 500Å is a controlled pore glass (CPG) with a pore size of 500 angstroms, featuring a 5-carboxyfluorescein (5-FAM) fluorophore linked through a long chain alkylamine (lcaa) spacer and protected by a dimethoxytrityl (DMT) group. This support is designed for the synthesis of 3'-fluorescein-labeled oligonucleotides. The DMT protecting group allows for efficient incorporation and subsequent deprotection during synthesis, while the lcaa linker enhances the accessibility and performance of the fluorophore. This material is commonly used in fluorescence-based detection, quantitative PCR (qPCR), and fluorescence resonance energy transfer (FRET) assays due to its strong and reliable fluorescence signals.

CAT: BRP-01367

Description: 8-Bromo Adenosine (n,n-dibuf) 3'-tBDSilyl 2'-lcaa CPG 500Å is a specialized solid support used in the synthesis of modified oligonucleotides. It facilitates the incorporation of 8-bromo adenosine into oligonucleotides. The modifications include a 3'-tert-butyldimethylsilyl (tBDSilyl) group for protecting the 3'-hydroxyl, and an n,n-dibutylformamidine (dibuf) protection on the adenosine base. The long chain alkylamine (lcaa) linker and the controlled pore glass (CPG) with 500Å pores ensure efficient solid-phase synthesis. The resulting oligonucleotides are useful in biochemical research for studying nucleic acid interactions and for therapeutic applications requiring enhanced stability and specific binding properties.

CAT: BRP-01369

Description: 5-Bromo Uridine 3'-tBDSilyl 2'-lcaa CPG 500Å is a specialized solid support used in the synthesis of modified oligonucleotides. It facilitates the incorporation of 5-Bromo uridine into oligonucleotides. It features a 3'-tert-butyldimethylsilyl (tBDSilyl) group protecting the 3'-hydroxyl, and a long chain alkylamine (lcaa) linker attached to controlled pore glass (CPG) with 500Å pores. The modification with 5-Bromo uridine provides enhanced stability and unique properties to the synthesized oligonucleotides, which are useful for various research applications, including studies of nucleic acid interactions and the development of therapeutic agents.

CAT: BRP-01370

Description: 5-Fluoro Uridine 3'-tBDSilyl 2'-lcaa CPG 1000Å is a specialized solid support used in the synthesis of modified oligonucleotides. It facilitates the incorporation of 5-fluoro uridine into oligonucleotides. It features a 3'-tert-butyldimethylsilyl (tBDSilyl) group protecting the 3'-hydroxyl, and a long chain alkylamine (lcaa) linker attached to controlled pore glass (CPG) with 1000Å pores. The modification with 5-fluoro uridine provides enhanced stability and unique properties to the synthesized oligonucleotides, which are useful for various research applications, including studies of nucleic acid interactions and the development of therapeutic agents.

CAT: BRP-01371

Description: 5-Bromo Cytidine (n-bz) 3'-tBDSilyl 2'-lcaa CPG 1000Å is a specialized solid support used in the synthesis of modified oligonucleotides. It facilitates the incorporation of 5-bromo cytidine into oligonucleotides. It includes a 5-bromo modification on the cytidine base, a benzoyl (n-bz) protecting group on the exocyclic amino group, a 3'-tert-butyldimethylsilyl (tBDSilyl) group protecting the 3'-hydroxyl, and a long chain alkylamine (lcaa) linker attached to controlled pore glass (CPG) with 1000Å pores. This setup ensures efficient solid-phase synthesis and provides the resulting oligonucleotides with enhanced stability and unique properties for various biochemical and therapeutic research applications.

CAT: BRP-01372

Description: 5-Iodo Cytidine (n-bz) 3'-tBDSilyl 2'-lcaa CPG 500Å is a specialized solid support used in the synthesis of modified oligonucleotides. It facilitates the incorporation of 5-iodo cytidine into oligonucleotides. It includes a 5-iodo modification on the cytidine base, a benzoyl (n-bz) protecting group on the exocyclic amino group, a 3'-tert-butyldimethylsilyl (tBDSilyl) group protecting the 3'-hydroxyl, and a long chain alkylamine (lcaa) linker attached to controlled pore glass (CPG) with 500Å pores. This setup ensures efficient solid-phase synthesis and provides the resulting oligonucleotides with enhanced stability and unique properties for various biochemical and therapeutic research applications.

CAT: BRP-01373

Description: 5-Iodo Uridine 3'-tBDSilyl 2'-lcaa CPG 1000Å is a specialized solid support used in the synthesis of modified oligonucleotides. It facilitates the incorporation of 5-Iodo uridine into oligonucleotides. It features a 3'-tert-butyldimethylsilyl (tBDSilyl) group protecting the 3'-hydroxyl, and a long chain alkylamine (lcaa) linker attached to controlled pore glass (CPG) with 1000Å pores. The modification with 5-Iodo uridine provides enhanced stability and unique properties to the synthesized oligonucleotides, which are useful for various research applications, including studies of nucleic acid interactions and the development of therapeutic agents.

CAT: BRP-01375

Description: isoGuanosine (n,n-isobudmf) 2'-lcaa CPG 1000Å is a specialized solid support used in oligonucleotide synthesis to incorporate modified guanosine, isoGuanosine, into nucleic acid sequences. This modification provides unique chemical properties, enabling tailored customization of oligonucleotides for diverse research and therapeutic applications.

CAT: BRP-01377

Description: IsoCytidine (n,n-diisobutylformamidine) 2'-lcaa CPG 1000Å is a specialized solid support used in oligonucleotide synthesis to introduce modified cytidine, IsoCytidine, into nucleic acid sequences. This modification offers unique chemical properties, allowing for customized oligonucleotide design for various research and therapeutic applications.

CAT: BRP-01379

Description: Beta-L-2'-tBDSilyl Guanosine (n-ibu) 3'-lcaa CPG 1000Å is a specialized solid support used in oligonucleotide synthesis to incorporate modified guanosine, specifically Beta-L-2'-tBDSilyl Guanosine, into nucleic acid sequences. This modification involves a Beta-L configuration at the 2'-position of the ribose sugar, a tert-butyldimethylsilyl (tBDSilyl) group at the 2'-position, and an n-ibu (n-isobutyryl) group at the nucleobase. Additionally, it features a long-chain alkylamine linker with controlled pore glass (CPG) having 1000 angstrom pores. This reagent facilitates the synthesis of oligonucleotides with unique structural and chemical properties for various research and therapeutic applications.

CAT: BRP-01380

Description: Beta-L-2'-tBDSilyl Adenosine (n-bz) 3'-lcaa CPG 1000Å is a specialized solid support used in oligonucleotide synthesis to incorporate modified adenosine, specifically Beta-L-2'-tBDSilyl Adenosine, into nucleic acid sequences. This modification involves a Beta-L configuration at the 2'-position of the ribose sugar, a tert-butyldimethylsilyl (tBDSilyl) group at the 2'-position, and a benzoyl (n-bz) group at the nucleobase. Additionally, it features a long-chain alkylamine linker with controlled pore glass (CPG) having 1000 angstrom pores. This reagent facilitates the synthesis of oligonucleotides with unique structural and chemical properties for various research and therapeutic applications.

CAT: BRP-01381

Description: Beta-L-2'-tBDSilyl Cytidine (n-bz) 3'-lcaa CPG 500Å is a specialized solid support used in oligonucleotide synthesis to incorporate modified cytidine, specifically Beta-L-2'-tBDSilyl Cytidine, into nucleic acid sequences. This modification involves a Beta-L configuration at the 2'-position of the ribose sugar, a tert-butyldimethylsilyl (tBDSilyl) group at the 2'-position, and a benzoyl (n-bz) group at the nucleobase. Additionally, it features a long-chain alkylamine linker with controlled pore glass (CPG) having 500 angstrom pores. This reagent facilitates the synthesis of oligonucleotides with unique structural and chemical properties for various research and therapeutic applications.

CAT: BRP-01383

Description: Beta-L-2'-tBDSilyl Uridine 3'-lcaa CPG 1000Å is a specialized solid support utilized in oligonucleotide synthesis to introduce modified uridine, specifically Beta-L-2'-tBDSilyl Uridine, into nucleic acid sequences. This modification involves a Beta-L configuration at the 2'-position of the ribose sugar, with a tert-butyldimethylsilyl (tBDSilyl) group attached. Additionally, it features a long-chain alkylamine linker with controlled pore glass (CPG) having 1000 angstrom pores. This reagent facilitates the synthesis of oligonucleotides with unique structural and chemical properties, suitable for various research and therapeutic applications.

CAT: BRP-01384

Description: Beta-L-2'-tBDSilyl Cytidine (n-acetyl) 3'-lcaa CPG 500Å is a specialized solid support used in oligonucleotide synthesis to incorporate modified cytidine, specifically Beta-L-2'-tBDSilyl Cytidine, into nucleic acid sequences. This modification includes a Beta-L configuration at the 2'-position of the ribose sugar, a tert-butyldimethylsilyl (tBDSilyl) group at the 2'-position, and an acetyl (n-acetyl) group at the nucleobase. Additionally, it features a long-chain alkylamine linker with controlled pore glass (CPG) having 500 angstrom pores. This reagent facilitates the synthesis of oligonucleotides with unique structural and chemical properties, suitable for various research and therapeutic applications.

CAT: BRP-01385

Description: 5-Methyl Cytidine (n,n-dmf) 2'-O-Methyl lcaa CPG 1000Å is a specialized solid support used in oligonucleotide synthesis to incorporate modified cytidine, specifically 5-methyl cytidine, into nucleic acid sequences. This modification introduces a methyl group at the 5-position of the cytidine base and features a long-chain alkylamine linker with controlled pore glass (CPG) having 1000 angstrom pores. This reagent enables the tailored synthesis of oligonucleotides with enhanced stability and specific chemical properties for diverse research and therapeutic applications.

CAT: BRP-01393

Description: 2'-O-Methyl Inosine lcaa CPG 500Å is a solid support reagent used in oligonucleotide synthesis. It features 2'-O-methyl inosine linked to long chain alkylamine (lcaa) on Controlled Pore Glass (CPG) with a pore size of 500 angstroms. This modification enhances the stability and nuclease resistance of synthesized oligonucleotides, making it suitable for various research and therapeutic applications.

CAT: BRP-01395

Description: 5-Bromo Uridine 2'-O-Methyl lcaa CPG 500Å is a reagent utilized in oligonucleotide synthesis. It contains 5-Bromo Uridine, where a bromine atom is attached to the 5-position of the uridine nucleoside, along with a methyl group at the 2'-position of the ribose sugar. The nucleoside is linked to a solid support using a long-chain alkylamine (lcaa) linker, and the support material is Controlled Pore Glass (CPG) with a pore size of 500 angstroms. This reagent is instrumental in the creation of oligonucleotides with enhanced stability and resistance to degradation, crucial for diverse research and diagnostic applications in molecular biology.

CAT: BRP-01398

Description: 5-Iodo Uridine 2'-O-Methyl lcaa CPG 500Å is a reagent used in oligonucleotide synthesis. It contains 5-Iodo Uridine, where an iodine atom is attached to the 5-position of the uridine nucleoside, along with a methyl group at the 2'-position of the ribose sugar. The nucleoside is linked to a solid support using a long-chain alkylamine (lcaa) linker, and the support material is Controlled Pore Glass (CPG) with a pore size of 500 angstroms. This reagent facilitates the synthesis of oligonucleotides with enhanced stability and resistance to degradation, important for various molecular biology applications.

CAT: BRP-01399

Description: 2-Amino Purine Riboside 3'-tBDSilyl 2'-lcaa CPG 1000Å is a modified nucleoside which is used as a building block for the synthesis of oligonucleotides. It contains a 2-amino purine base, a ribose sugar, and a protecting group at the 3'-position. The 2'-lcaa CPG refers to the controlled pore glass (CPG) support with a linker attached to the 2'-position of the ribose sugar. The 1000Å designation refers to the pore size of the CPG support, indicating the size of molecules that can be efficiently synthesized on this support. This compound is commonly used in the field of molecular biology and nucleic acid research for the synthesis of modified oligonucleotides with specific properties.

CAT: BRP-01403