What pore size CPG is recommended for long oligonucleotide synthesis?

For long DNA or RNA sequences, 1000 Å or 2000 Å CPG is generally recommended to improve reagent diffusion and maintain coupling efficiency during extended synthesis cycles.

How does loading capacity affect CDMO manufacturing projects?

Loading capacity influences both yield and coupling efficiency. Controlled and reproducible loading is essential for minimizing batch-to-batch variability in long-term manufacturing programs.

Do you provide COA and batch traceability?

Each batch is supplied with a Certificate of Analysis (COA) and full traceability to support audits and quality reviews.

Can you support material supply during process scale-up?

Yes. We support material supply from early process development through scale-up and routine manufacturing.

How should CPGs be stored?

CPGs should be stored in a dry, tightly sealed container at room temperature to maintain surface functionality and consistent performance.

Control Pore Glass - RNA / BOC Sciences

2'-O-Methyl Guanosine (n-PAC) 3'-lcaa CPG

Description: 2'-O-Methyl Guanosine (n-PAC) 3'-lcaa CPG refers to a specialized solid support utilized in oligonucleotide synthesis. It consists of a controlled-pore glass (CPG) matrix functionalized with a linker molecule featuring a 3'-lcaa moiety and modified with a 2'-O-Methyl Guanosine (n-PAC) group. This support facilitates the stepwise assembly of nucleotide sequences during automated oligonucleotide synthesis. The specific functional groups on the support enable controlled chemical reactions, ensuring precise and efficient synthesis of oligonucleotides. These synthesized oligonucleotides have various applications in molecular biology, genetics, diagnostics, and therapeutics.

CAT: BRP-01269

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Synonyms: 2'-O-Methyl Guanosine (n-PAC) 3'-lcaa CPG 1000Å; 2'-O-Methyl Guanosine (n-PAC) 3'-lcaa CPG 500Å

2'-O-Methyl Uridine 3'-lcaa CPG 500Å

Description: 2'-O-Methyl Uridine 3'-lcaa CPG 500Å is a specialized solid support used in oligonucleotide synthesis. It consists of a controlled-pore glass (CPG) matrix with a pore size of 500 angstroms, functionalized with a linker molecule featuring a 3'-lcaa moiety and modified with a 2'-O-Methyl Uridine group. This support facilitates the stepwise assembly of nucleotide sequences during automated oligonucleotide synthesis. The specific functional groups on the support enable controlled chemical reactions, ensuring precise and efficient synthesis of oligonucleotides. These synthesized oligonucleotides have various applications in molecular biology, genetics, diagnostics, and therapeutics.

CAT: BRP-01272

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Synonyms: 2'-O-Methyl Uridine 3'-lcaa CPG 1000Å; 2'-O-Methyl Uridine 3'-lcaa CPG

2'-O-Methyl Cytidine (n-acetyl) 3'-lcaa CPG 500Å

Description: 2'-O-Methyl Cytidine (N-acetyl) 3'-lcaa CPG 500Å is a specialized solid support used in oligonucleotide synthesis. It comprises a controlled-pore glass (CPG) matrix with a pore size of 500 angstroms, functionalized with a linker molecule containing a 3'-lcaa moiety and modified with a 2'-O-Methyl Cytidine group protected by an acetyl (N-acetyl) group. This support facilitates the sequential assembly of nucleotide sequences during automated oligonucleotide synthesis. The specific functional groups on the support enable controlled chemical reactions, ensuring precise and efficient synthesis of oligonucleotides. These synthesized oligonucleotides find applications in various fields such as molecular biology, genetics, diagnostics, and therapeutics.

CAT: BRP-01273

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Synonyms: 2'-O-Methyl Cytidine (n-acetyl) 3'-lcaa CPG; 2'-O-Methyl Cytidine (n-acetyl) 3'-lcaa CPG 1000Å

2'-O-propargyl Adenosine (n-bz) 3'-lcaa CPG 500Å

Description: 2'-O-Propargyl Adenosine (n-bz) 3'-LCAA CPG 500Å is a modified adenosine nucleoside used in solid-phase oligonucleotide synthesis. It features a propargyl group at the 2' position and a benzoyl-protected adenine base, attached to long-chain alkylamine controlled pore glass (LCAA CPG) with a 500Å pore size. This compound is useful for creating stable and functionalized RNA and DNA sequences for advanced genetic and biochemical research.

CAT: BRP-01283

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Synonyms: 2'-O-propargyl Adenosine (n-bz) 3'-lcaa CPG; 2'-O-propargyl Adenosine (n-bz) 3'-lcaa CPG 1000Å

2'-O-propargyl Cytidine (n-bz) 3'-lcaa CPG 500Å

Description: 2'-O-Propargyl Cytidine (N-bz) 3'-lcaa CPG 500Å is a specialized solid support used in oligonucleotide synthesis. It comprises a controlled-pore glass (CPG) matrix with a pore size of 500 angstroms, functionalized with a linker molecule featuring a 2'-O-propargyl cytidine (N-bz) group and a 3'-lcaa moiety. This support facilitates the sequential assembly of nucleotide sequences during automated oligonucleotide synthesis. The specific functional groups on the support enable controlled chemical reactions, ensuring precise and efficient synthesis of oligonucleotides. These synthesized oligonucleotides have various applications in molecular biology, genetics, and diagnostics.

CAT: BRP-01284

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Synonyms: 2'-O-propargyl Cytidine (n-bz) 3'-lcaa CPG 1000Å; 2'-O-propargyl Cytidine (n-bz) 3'-lcaa CPG

2'-O-propargyl Guanosine (n-ibu) 3'-lcaa CPG 500Å

Description: 2'-O-Propargyl Guanosine (N-ibu) 3'-lcaa CPG 500Å is a specialized solid support used in oligonucleotide synthesis. It consists of a controlled-pore glass (CPG) matrix with a pore size of 500 angstroms, functionalized with a linker molecule featuring a 2'-O-propargyl guanosine (N-ibu) group and a 3'-lcaa moiety. This support facilitates the sequential assembly of nucleotide sequences during automated oligonucleotide synthesis. The specific functional groups on the support enable controlled chemical reactions, ensuring precise and efficient synthesis of oligonucleotides. These synthesized oligonucleotides have various applications in molecular biology, genetics, and diagnostics.

CAT: BRP-01285

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Synonyms: 2'-O-propargyl Guanosine (n-ibu) 3'-lcaa CPG 1000Å; 2'-O-propargyl Guanosine (n-ibu) 3'-lcaa CPG

2'-O-propargyl Uridine 3'-lcaa CPG 500Å

Description: 2'-O-Propargyl Uridine 3'-lcaa CPG 500Å is a specialized solid support utilized in oligonucleotide synthesis. It comprises a controlled-pore glass (CPG) matrix with a pore size of 500 angstroms, functionalized with a linker molecule featuring a 2'-O-propargyl uridine group and a 3'-lcaa moiety. This support facilitates the stepwise assembly of nucleotide sequences during automated oligonucleotide synthesis. The specific functional groups on the support enable controlled chemical reactions, ensuring precise and efficient synthesis of oligonucleotides. These synthesized oligonucleotides have various applications in molecular biology, genetics, and diagnostics.

CAT: BRP-01286

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Synonyms: 2'-O-propargyl Uridine 3'-lcaa CPG 1000Å; 2'-O-propargyl Uridine 3'-lcaa CPG

3'-O-Methyl Adenosine (n-bz) 2'-lcaa CPG 1000Å

Description: 3'-O-Methyl Adenosine (n-bz) 2'-lcaa CPG 1000Å is a type of solid support commonly used in oligonucleotide synthesis. It consists of a long-chain polymer matrix with a pore size of 1000Å, functionalized with a linker molecule containing a 3'-O-Methyl Adenosine (n-bz) group and a 2'-lcaa moiety. This support is utilized in automated oligonucleotide synthesis to anchor the growing nucleotide chain during the stepwise assembly of DNA or RNA sequences. The functional groups on the support facilitate controlled chemical reactions, enabling efficient and high-fidelity synthesis of oligonucleotides for various research and diagnostic applications.

CAT: BRP-01288

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Synonyms: 3'-O-Methyl Adenosine (n-bz) 2'-lcaa CPG 500Å; 3'-O-Methyl Adenosine (n-bz) 2'-lcaa CPG; 3'-O-Me A(Bz) 2'-lcaa CPG

3'-O-Methyl Cytidine (n-bz) 2'-lcaa CPG 1000Å

Description: 3'-O-Methyl Cytidine (n-bz) 2'-lcaa CPG 1000Å is a type of solid support commonly employed in oligonucleotide synthesis. It consists of a controlled-pore glass (CPG) matrix with a pore size of 1000 angstroms, functionalized with a linker molecule containing a 3'-O-Methyl Cytidine (n-bz) group and a 2'-lcaa moiety. This support facilitates the stepwise assembly of nucleotide sequences during automated oligonucleotide synthesis. The specific functional groups on the support enable precise chemical reactions, ensuring accurate and efficient synthesis of oligonucleotides for various applications in molecular biology, genetics, and diagnostics.

CAT: BRP-01289

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Synonyms: 3'-O-Methyl Cytidine (n-bz) 2'-lcaa CPG 500Å; 3'-O-Methyl Cytidine (n-bz) 2'-lcaa CPG; 3'-O-Me C(Bz) 2'-lcaa CPG

3'-O-Methyl Guanosine (n-ibu) 2'-lcaa CPG 1000Å

Description: 3'-O-Methyl Guanosine (n-ibu) 2'-lcaa CPG 1000Å is a specialized solid support utilized in oligonucleotide synthesis. It consists of a controlled-pore glass (CPG) matrix with a pore size of 1000 angstroms, modified with a linker molecule incorporating a 3'-O-Methyl Guanosine (n-ibu) group and a 2'-lcaa moiety. This support enables the sequential assembly of nucleotide sequences during automated oligonucleotide synthesis. The presence of specific functional groups on the support facilitates controlled chemical reactions, ensuring precise and efficient synthesis of oligonucleotides. These synthesized oligonucleotides find applications in various fields, including molecular biology, genetics, and diagnostics.

CAT: BRP-01290

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Synonyms: 3'-O-Methyl Guanosine (n-ibu) 2'-lcaa CPG 500Å; 3'-O-Methyl Guanosine (n-ibu) 2'-lcaa CPG; 3'-O-Me G(iBu) 2'-lcaa CPG

3'-O-Methyl Uridine 2'-lcaa CPG 500Å

Description: 3'-O-Methyl Uridine 2'-lcaa CPG 500Å is a specialized solid support used in oligonucleotide synthesis. It consists of a controlled-pore glass (CPG) matrix with a pore size of 500 angstroms, functionalized with a linker molecule featuring a 3'-O-Methyl Uridine group and a 2'-lcaa moiety. This support facilitates the sequential assembly of nucleotide sequences during automated oligonucleotide synthesis. The specific functional groups on the support enable controlled chemical reactions, ensuring precise and efficient synthesis of oligonucleotides. These synthesized oligonucleotides find applications in various fields, including molecular biology, genetics, and diagnostics.

CAT: BRP-01291

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Synonyms: 3'-O-Methyl Uridine 2'-lcaa CPG 1000Å; 3'-O-Methyl Uridine 2'-lcaa CPG; 3'-O-Me U 2'-lcaa CPG

3'-O-Methyl Inosine 2'-lcaa CPG 500Å

Description: 3'-O-Methyl Inosine 2'-lcaa CPG 500Å is a specialized solid support used in oligonucleotide synthesis. It comprises a controlled-pore glass (CPG) matrix with a pore size of 500 angstroms, functionalized with a linker molecule featuring a 3'-O-Methyl Inosine group and a 2'-lcaa moiety. This support facilitates the stepwise assembly of nucleotide sequences during automated oligonucleotide synthesis. The specific functional groups on the support enable controlled chemical reactions, ensuring precise and efficient synthesis of oligonucleotides. These synthesized oligonucleotides have various applications in molecular biology, genetics, and diagnostics.

CAT: BRP-01292

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Synonyms: 3'-O-Methyl Inosine 2'-lcaa CPG 1000Å; 3'-O-Methyl Inosine 2'-lcaa CPG; 3'-O-Me I 2'-lcaa CPG

3'-O-propargyl Adenosine (n-bz) 2'-lcaa CPG 500Å

Description: 3'-O-Propargyl Adenosine (n-bz) 2'-LCAA CPG 500Å is a modified adenosine nucleoside used in solid-phase oligonucleotide synthesis. It features a propargyl group at the 3' position and a benzoyl-protected adenine base, attached to long-chain alkylamine controlled pore glass (LCAA CPG) with a 500Å pore size. This compound is utilized for creating functionalized and stable RNA and DNA sequences, supporting advanced genetic and biochemical research.

CAT: BRP-01295

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Synonyms: 3'-O-propargyl Adenosine (n-bz) 2'-lcaa CPG 1000Å; 3'-O-propargyl Adenosine (n-bz) 2'-LCAA CPG; 3'-O-propargyl A(Bz) 2'-lcaa CPG

3'-O-propargyl Cytidine (n-bz) 2'-lcaa CPG 500Å

Description: 3'-O-Propargyl Cytidine (n-bz) 2'-LCAA CPG 500Å is a modified cytidine nucleoside used in solid-phase oligonucleotide synthesis. It features a propargyl group at the 3' position and a benzoyl-protected cytosine base, attached to long-chain alkylamine controlled pore glass (LCAA CPG) with a 500Å pore size. This compound is utilized for creating functionalized and stable RNA and DNA sequences, facilitating advanced genetic and biochemical research.

CAT: BRP-01296

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Synonyms: 3'-O-propargyl Cytidine (n-bz) 2'-lcaa CPG 1000Å; 3'-O-propargyl Cytidine (n-bz) 2'-LCAA CPG; 3'-O-propargyl C(Bz) 2'-lcaa CPG

3'-O-propargyl Guanosine (n-ibu) 2'-lcaa CPG 500Å

Description: 3'-O-Propargyl Guanosine (n-ibu) 2'-LCAA CPG 500Å is a modified guanosine nucleoside used in solid-phase oligonucleotide synthesis. It features a propargyl group at the 3' position and an isobutyryl-protected guanine base, attached to long-chain alkylamine controlled pore glass (LCAA CPG) with a 500Å pore size. This compound is used for creating functionalized and stable RNA and DNA sequences, facilitating advanced genetic and biochemical research.

CAT: BRP-01297

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Synonyms: 3'-O-propargyl Guanosine (n-ibu) 2'-lcaa CPG 1000Å; 3'-O-propargyl Guanosine (n-ibu) 2'-LCAA CPG; 3'-O-propargyl G(iBu) 2'-lcaa CPG

3'-O-propargyl Uridine 2'-lcaa CPG 500Å

Description: 3'-O-Propargyl Uridine 2'-LCAA CPG 500Å is a modified uridine nucleoside used in solid-phase oligonucleotide synthesis. It features a propargyl group at the 3' position, attached to long-chain alkylamine controlled pore glass (LCAA CPG) with a 500Å pore size. This compound is employed to create stable and functionalized RNA and DNA sequences, supporting advanced genetic and biochemical research.

CAT: BRP-01298

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Synonyms: 3'-O-propargyl Uridine 2'-lcaa CPG 1000Å; 3'-O-propargyl Uridine 2'-LCAA CPG; 3'-O-propargyl U 2'-lcaa CPG

N4-Ethyl Cytidine 3'-tBDSilyl 2'-lcaa CPG 1000Å

Description: N4-Ethyl Cytidine 3'-tBDSilyl 2'-lcaa CPG 1000Å is a specialized solid support utilized in oligonucleotide synthesis. It consists of a controlled-pore glass (CPG) matrix with a pore size of 1000 angstroms, functionalized with a linker molecule featuring a N4-Ethyl Cytidine group, a 3'-tBDSilyl modification, and a 2'-lcaa moiety. This support facilitates the stepwise assembly of nucleotide sequences during automated oligonucleotide synthesis. The specific functional groups on the support enable controlled chemical reactions, ensuring precise and efficient synthesis of oligonucleotides. These synthesized oligonucleotides have various applications in molecular biology, genetics, and diagnostics.

CAT: BRP-01302

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Synonyms: N4-Ethyl Cytidine 3'-tBDSilyl 2'-lcaa CPG 500Å; N4-Ethyl Cytidine 3'-tBDSilyl 2'-lcaa CPG

Pyridine-2-One-3'-tBDSilyl 2'-lcaa CPG 500Å

Description: Pyridine-2-One-3'-tBDSilyl 2'-lcaa CPG 500Å is a specialized solid support employed in oligonucleotide synthesis. It comprises a controlled-pore glass (CPG) matrix with a pore size of 500 angstroms, modified with a linker molecule containing a Pyridine-2-One-3'-tBDSilyl group and a 2'-lcaa moiety. This support enables the sequential assembly of nucleotide sequences during automated oligonucleotide synthesis. The specific functional groups on the support facilitate controlled chemical reactions, ensuring precise and efficient synthesis of oligonucleotides. These synthesized oligonucleotides have various applications in molecular biology, genetics, and diagnostics.

CAT: BRP-01304

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Synonyms: Pyridine-2-One-3'-tBDSilyl 2'-lcaa CPG 1000Å; Pyridine-2-One-3'-tBDSilyl 2'-lcaa CPG

7-Deaza Guanosine (n-ibu) 2'-lcaa CPG 1000Å

Description: 7-Deaza Guanosine (n-ibu) 2'-lcaa CPG 1000Å refers to a specialized solid support utilized in oligonucleotide synthesis. It consists of a controlled-pore glass (CPG) matrix with a pore size of 1000 angstroms, functionalized with a linker molecule containing a 2'-lithium cyanoethylamine (2'-lcaa) moiety. Additionally, it is modified with 7-Deaza Guanosine, which is an analog of guanosine with a nitrogen atom replacing the carbon at the 7-position of the purine ring. This modification enhances base pairing specificity in nucleotide sequences. The 7-Deaza Guanosine is further protected with an isobutyryl (n-ibu) group. This specialized support facilitates precise and efficient oligonucleotide synthesis, making it valuable for applications in molecular biology, genetics, diagnostics, and therapeutics.

CAT: BRP-01324

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Synonyms: 7-Deaza Guanosine (n-ibu) 2'-lcaa CPG 500Å; 7-Deaza Guanosine (n-ibu) 2'-lcaa CPG; 7-Deaza 3'-TBDMS Guanosine (n-ibu) 2'-lcaa CPG

7-Deaza Adenosine (n-bz) 2'-lcaa CPG 1000Å

Description: 7-Deaza Adenosine (n-bz) 2'-lcaa CPG 1000Å is a specialized solid support used in oligonucleotide synthesis. It consists of a controlled-pore glass (CPG) matrix with a pore size of 1000 angstroms, functionalized with a linker molecule containing a 2'-lithium cyanoethylamine (2'-lcaa) group. Additionally, it is modified with 7-Deaza Adenosine, an adenosine analog where a nitrogen atom replaces the carbon at the 7-position of the purine ring. This modification enhances base pairing specificity in nucleotide sequences. The 7-Deaza Adenosine is further protected with a benzoyl (n-bz) group. This specialized support facilitates precise and efficient oligonucleotide synthesis, crucial for various applications in molecular biology, genetics, diagnostics, and therapeutics.

CAT: BRP-01325