Nucleosides

2'-Modified Nucleosides
(303/303)
3'-Modified Nucleosides
(173/173)
5'-Modified Nucleosides
(252/252)
Anhydro-Nucleosides
(13/13)
Arabinonucleosides
(34/34)
Base Protected Nucleosides
(234/234)
Halogen Nucleosides
(134/134)
L-Nucleosides
(18/18)
Other Nucleosides
(77/77)
Other Protected Nucleosides
(23/23)
Ribonucleosides
(11/11)
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2'-C-beta-Methylguanosine

Description: 2'-C-β-Methyl Guanosine is an anti-HCV agent. 2'-C-β-Methyl Guanosine is an intermediate in the synthesis of novel double prodrug INX-08189, a new clinical candidate for hepatitis C virus.
CAT: BRP-00060
CAS: 374750-30-8
Molecular Formula: C11H15N5O5
Molecular Weight: 297.27
Purity: ≥95%
Appearance: White to Beige Powder
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Storage: Store at -20°C
Density: 2.03 g/cm3
Boiling Point: 733.1±70.0°C (Predicted)
Application: A nucleoside derivative as antiviral, antitumor, and antidiabetic prodrug agents.
InChIKey: NVKAMPJSWMHVDK-GITKWUPZSA-N
Solubility: Soluble in Water
CanonicalSMILES: CC1(C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O)O
IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1H-purin-6-one
InChI: InChI=1S/C11H15N5O5/c1-11(20)6(18)4(2-17)21-9(11)16-3-13-5-7(16)14-10(12)15-8(5)19/h3-4,6,9,17-18,20H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,9-,11-/m1/s1
Synonyms: 2'-C-Methylguanosine; 2'-C-β-Methyl Guanosine; 2-Amino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-(2-C-methyl-beta-D-ribofuranosyl)-; INX 08032; INZ 08032

2'-C-Methyluridine

Description: 2'-C-Methyluridine is a 2'-C-Me branched C-nucleoside that shows HCV polymerase inhibitory activity.
CAT: BRP-00061
CAS: 31448-54-1
Molecular Formula: C10H14N2O6
Molecular Weight: 258.23
Purity: ≥95%
Appearance: White to Off-white Powder
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Storage: Store at 2-8°C
Density: 1.57 g/cm3
Melting Point: 110-112 °C
InChIKey: NBKORJKMMVZAOZ-VPCXQMTMSA-N
CanonicalSMILES: CC1(C(C(OC1N2C=CC(=O)NC2=O)CO)O)O
IUPAC Name: 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C10H14N2O6/c1-10(17)7(15)5(4-13)18-8(10)12-3-2-6(14)11-9(12)16/h2-3,5,7-8,13,15,17H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,10-/m1/s1
Synonyms: 2'-C-Methyl-1-β-D-ribofuranosyluracil; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Methyl Uridine; 1,3-bis(N-cyclohexyl)guanidine; 1-(2-C-Methyl-β-D-ribofuranosyl)uracil; 2,4(1H,3H)-pyrimidinedione, 1-(2-C-methyl-β-D-ribofuranosyl)-

N6-Cyclopentyl-adenosine

Description: N6-Cyclopentyl-adenosine (CPA) - an adenosine analog and A1 adenosine receptor agonist - is pivotal in biomedicine as a research tool to inspect the part played by the adenosine receptor in distinct physiological processes. It also has potential therapeutic benefits that range from treating ischemia-reperfusion injuries to chronic pain.
CAT: BRP-00062
CAS: 41552-82-3
Molecular Formula: C15H21N5O4
Molecular Weight: 335.36
Purity: ≥95% by HPLC
Appearance: White to off-white solid
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Storage: Store at 2-8 °C
Density: 1.78±0.1 g/cm3 (Predicted)
Melting Point: 78.8 °C
Boiling Point: 673.4±65.0 °C at 760 mmHg
Application: Purinergic P1 Receptor Agonists
InChIKey: SQMWSBKSHWARHU-SDBHATRESA-N
Solubility: Soluble in Water
CanonicalSMILES: C1CCC(C1)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O
IUPAC Name: (2R,3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
InChI: InChI=1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1
Synonyms: N6-Cyclopentyladenosine; CPA; N-Cyclopentyladenosine; UK 80882; (2R,3R,4S,5R)-2-[6-(Cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

EIDD-2749

Description: 4'-Fluorouridine is an orally active RdRp inhibitor. It effectively blocks the replication of RSV and SARS-CoV-2.
CAT: BRP-00063
CAS: 1613589-24-4
Molecular Formula: C9H11FN2O6
Molecular Weight: 262.19
Purity: 98%
Appearance: Solid
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Density: 1.77±0.1 g/cm3
InChIKey: RDCYLPRXPILMRP-JVZYCSMKSA-N
CanonicalSMILES: O=C1NC(N([C@@H]2O[C@@](CO)(F)[C@@H](O)[C@H]2O)C=C1)=O
IUPAC Name: 1-[(2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C9H11FN2O6/c10-9(3-13)6(16)5(15)7(18-9)12-2-1-4(14)11-8(12)17/h1-2,5-7,13,15-16H,3H2,(H,11,14,17)/t5-,6+,7-,9-/m1/s1
Synonyms: 4'-fluorouridine;1613589-24-4;4'-C-Fluoro-uridine;1-[(2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione;1613591-91-5;SCHEMBL6839661;RDCYLPRXPILMRP-JVZYCSMKSA-N;AMY30709;EX-A6732;DA-70078;MS-23688;4'-fluorouridine (4'-FlU, EIDD-2749)?;1-((2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione;

3'-O-Methyluridine

Description: 3'-O-Methyluridine is a potent compound, serving as a therapeutic intervention for research of diverse viral infections and autoimmune conditions. Through its exceptional anti-replication properties, this remarkable compound effectively hampers viral proliferation.
CAT: BRP-00064
CAS: 6038-59-1
Molecular Formula: C10H14N2O6
Molecular Weight: 258.23
Purity: ≥95%
Appearance: White to Off-white Powder
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Storage: Store at -20°C
Density: 1.53±0.1 g/cm3
Melting Point: 142-145°C
InChIKey: YKNATSNMFLEFRB-ZOQUXTDFSA-N
CanonicalSMILES: COC1C(OC(C1O)N2C=CC(=O)NC2=O)CO
IUPAC Name: 1-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C10H14N2O6/c1-17-8-5(4-13)18-9(7(8)15)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,9-/m1/s1
Synonyms: 3'-O-Methyl-D-uridine; O3'-methyl-uridine; 1-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 3'-O-Me-Ur; 3'-O-methyl-uridine; 3'-(O-Methyl) Uridine

3'-O-Methyladenosine

Description: 3'-O-Methyladenosine, an indispensable biomolecule utilized in the realm of biomedical research, assumes a pivotal role in the meticulous exploration of RNA modifications. Ubiquitously present within a myriad of RNA molecules, this compound exerts profound influence on gene expression regulation, cellular signaling, and the genesis of diseases.
CAT: BRP-00065
CAS: 10300-22-8
Molecular Formula: C11H15N5O4
Molecular Weight: 281.27
Purity: ≥95%
Appearance: White Powder
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Storage: Store at -20°C
Density: 1.84±0.1 g/cm3(Predicted)
Melting Point: 177-178 °C
Boiling Point: 623.8±65.0 °C(Predicted)
InChIKey: RYAFZRROCNNRFK-IOSLPCCCSA-N
Solubility: Soluble in Methanol (10 mg/mL)
CanonicalSMILES: COC1C(OC(C1O)N2C=NC3=C(N=CN=C32)N)CO
IUPAC Name: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-methoxyoxolan-3-ol
InChI: InChI=1S/C11H15N5O4/c1-19-8-5(2-17)20-11(7(8)18)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1
Synonyms: 3'-O-Methyl-D-adenosine; (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; NSC 103062; 3'-O-Methyl Adenosine; 3'-(O-Methyl) Adenosine

2'-O-Methyladenosine

Description: 2'-O-Methyladenosine is a modified nucleoside where a methyl group is attached to the 2' hydroxyl of the ribose sugar. This modification enhances the stability and binding affinity of RNA molecules, making it valuable in research focused on RNA structure, function, and therapeutic development. It is commonly used in the synthesis of chemically modified RNA for studies in molecular biology and biotechnology.
CAT: BRP-00066
CAS: 2140-79-6
Molecular Formula: C11H15N5O4
Molecular Weight: 281.27
Purity: ≥95%
Appearance: White to Off-white Solid
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Storage: Store at 2-8°C
Density: 1.84±0.1 g/cm3 (Predicted)
Melting Point: 198-200°C
Boiling Point: 623.8±65.0°C (Predicted)
Symbol: Am
InChIKey: FPUGCISOLXNPPC-IOSLPCCCSA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated, Sonicated), Water (Slightly)
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)N)CO)O
IUPAC Name: (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol
InChI: InChI=1S/C11H15N5O4/c1-19-8-7(18)5(2-17)20-11(8)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1
Synonyms: Adenosine, 2'-O-methyl-; (2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; Cordysinin B; 2'-O-Methyl-D-adenosine; 2'-O-Me-adenosine; 2'-(O-Methyl) Adenosine; 2'-O-Me-Ado

N6-Benzoyl-2'-O-methyladenosine

Description: N6-Benzoyl-2'-O-methyladenosine is an indispensable compound in the realm of biomedical research assuming a paramount role in the exploration of RNA modifications and epigenetics.
CAT: BRP-00067
CAS: 85079-00-1
Molecular Formula: C18H19N5O5
Molecular Weight: 385.37
Purity: ≥95%
Appearance: Off-white to Pale Yellow Powder
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Storage: Store at RT
Density: 1.59±0.1 g/cm3 (Predicted)
InChIKey: PHFHSPQCDRKMQJ-XWXWGSFUSA-N
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O
IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C18H19N5O5/c1-27-14-13(25)11(7-24)28-18(14)23-9-21-12-15(19-8-20-16(12)23)22-17(26)10-5-3-2-4-6-10/h2-6,8-9,11,13-14,18,24-25H,7H2,1H3,(H,19,20,22,26)/t11-,13-,14-,18-/m1/s1
Synonyms: N6-Benzoyl-2'-O-methyl-D-adenosine; Bz-2'-OMe-A; N-Benzoyl-2'-O-methyladenosine; N6-Benzoyl-2'-O-methyl-adenosine; 2'-O-methyl-N6-benzoyladenosine; N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; N6-Bz-2'-OMe-A; N6-Bz-2'-O-Me-Ar

N2-Isobutyryl-2'-O,4'-C-methyleneguanosine

Description: N2-Isobutyryl-2'-O,4'-C-methyleneguanosine is a potent antiviral compound used in the biomedical industry. It exhibits inhibitory activity against RNA viruses like Dengue and Zika viruses. This compound blocks viral replication by interfering with viral RNA synthesis. Its unique chemical structure makes it a valuable tool in antiviral drug discovery and development.
CAT: BRP-00069
CAS: 206055-68-7
Molecular Formula: C15H19N5O6
Molecular Weight: 365.34
Purity: ≥95%
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Density: 1.87±0.1 g/cm3
Melting Point: 196-199 °C
InChIKey: FUKSKECTPBMMEQ-BQOLRUCTSA-N
Solubility: Soluble in Water
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C4C(C(O3)(CO4)CO)O
IUPAC Name: N-[9-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C15H19N5O6/c1-6(2)11(23)18-14-17-10-7(12(24)19-14)16-5-20(10)13-8-9(22)15(3-21,26-13)4-25-8/h5-6,8-9,13,21-22H,3-4H2,1-2H3,(H2,17,18,19,23,24)/t8-,9+,13-,15+/m1/s1
Synonyms: guanosine, 2'-O,4'-C-methylene-N-(2-methyl-1-oxopropyl)-; (1S,3R,4R,7S)-7-Hydroxy-1-hydroxymethyl-3-(2-N-isobutyrylguanin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane; N-[6,9-Dihydro-6-oxo-9-[(1S,3R,4R,7S)-1-(hydroxymethyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptane-3-yl]-1H-purine-2-yl]isobutyramide

2'-O,4'-C-Methyleneuridine

Description: 2'-O,4'-C-Methyleneuridine, a biomedical compound, plays a pivotal role in the advancement of antiviral drugs and therapeutics. Its profound efficacy against a wide array of viral infections, namely hepatitis C virus (HCV) and respiratory syncytial virus (RSV), unveils its tremendous potential in combatting viral diseases.
CAT: BRP-00070
CAS: 200435-92-3
Molecular Formula: C10H12N2O6
Molecular Weight: 256.21
Purity: ≥95%
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Storage: Store at -20 °C
Density: 1.695 g/cm3
Melting Point: 239-243°C (methanol)
InChIKey: KNLNWXXWKDEEFW-JIOCBJNQSA-N
Solubility: Soluble in Methanol
CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=CC(=O)NC3=O)O)CO
IUPAC Name: 1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C10H12N2O6/c13-3-10-4-17-6(7(10)15)8(18-10)12-2-1-5(14)11-9(12)16/h1-2,6-8,13,15H,3-4H2,(H,11,14,16)/t6-,7+,8-,10+/m1/s1
Synonyms: 1-(2-O,4-C-Methylene-beta-D-ribofuranosyl)uracil; LNA-U; 1-[2,5-Anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-2,4(1H,3H)-pyrimidinedione; (1S,3R,4R,7S)-7-Hydroxy-1-hydroxymethyl-3-(uracil-1-yl)-2,5-dioxabicyclo-[2.2.1]heptane

5-Methyl-2'-O,4'-C-methyleneuridine

Description: 5-Methyl-2'-O,4'-C-methyleneuridine is a chemically modified nucleoside where a methylene bridge connects the 2'-oxygen and 4'-carbon of the ribose sugar, and the uridine base is methylated at the 5-position. This modification enhances the stability and binding affinity of RNA molecules, making it valuable in RNA research and therapeutic applications. It is often used to study RNA structure, function, and interactions, and in the development of novel RNA-based drugs.
CAT: BRP-00071
CAS: 206055-67-6
Molecular Formula: C11H14N2O6
Molecular Weight: 270.24
Purity: ≥95%
Appearance: White to light brown powder
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Storage: Store at 2-8 °C
Density: 1.598±0.1 g/cm3 (Predicted)
Melting Point: 196-198 °C
InChIKey: TYYUAZVXLRMUMN-SZVQBCOZSA-N
CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C3C(C(O2)(CO3)CO)O
IUPAC Name: 1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylpyrimidine-2,4-dione
InChI: InChI=1S/C11H14N2O6/c1-5-2-13(10(17)12-8(5)16)9-6-7(15)11(3-14,19-9)4-18-6/h2,6-7,9,14-15H,3-4H2,1H3,(H,12,16,17)/t6-,7+,9-,11+/m1/s1
Synonyms: LNA-5MeU; 1-[(1S,3R,4R,7S)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)thymine; 1-[2,5-Anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione

2'-O,4'-C-Methyleneadenosine

Description: 2'-O,4'-C-Methyleneadenosine is a highly versatile compound, skillfully inhibiting the replication of malignant cells and viruses to effectively disrupts the pathogenic cascade.
CAT: BRP-00072
CAS: 206055-70-1
Molecular Formula: C11H13N5O4
Molecular Weight: 279.25
Purity: ≥95%
Appearance: White to Off-white Powder
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Storage: Store at 2-8°C
Density: 2.14±0.1 g/cm3
Melting Point: 267-270°C
Boiling Point: 660.0±65.0°C at 760 mmHg
Shelf Life: >2 years if stored properly
InChIKey: GHKDRNDFVCEETA-KYAGDKKUSA-N
Solubility: Soluble in DMSO
CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=NC4=C(N=CN=C43)N)O)CO
IUPAC Name: (1S,3R,4R,7S)-3-(6-aminopurin-9-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-ol
InChI: InChI=1S/C11H13N5O4/c12-8-5-9(14-3-13-8)16(4-15-5)10-6-7(18)11(1-17,20-10)2-19-6/h3-4,6-7,10,17-18H,1-2H2,(H2,12,13,14)/t6-,7+,10-,11+/m1/s1
Synonyms: (1S,3R,4R,7S)-3-(6-amino-9H-purin-9-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-ol; LNA-Adenosine; (1S,3R,4R,7S)-7-Hydroxy-1-hydroxymethyl-3-(adenin-9-yl)-2,5-dioxabicyclo-[2.2.1]heptane; 9H-Purin-6-amine, 9-[2,5-anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-; 9-[2,5-Anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-9H-purin-6-amine; LNA-A diol; 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)adenine; LNA-A

2'-O,4'-C-Methylenecytidine

Description: 2'-O,4'-C-Methylenecytidine is a highly imperative compound in the field of compound, finding its application in the development of antiviral medications. Underpinning its significance, this exquisite compound assuming a pivotal role in impeding viral replication dynamics.
CAT: BRP-00073
CAS: 206055-69-8
Molecular Formula: C10H13N3O5
Molecular Weight: 255.23
Purity: ≥95%
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Density: 2.0±0.1 g/cm3
Melting Point: 274-276 °C
Boiling Point: 532.9±60.0°C at 760 mmHg
InChIKey: FCMRQQIZHFHCNG-JIOCBJNQSA-N
CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=CC(=NC3=O)N)O)CO
IUPAC Name: 4-amino-1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]pyrimidin-2-one
InChI: InChI=1S/C10H13N3O5/c11-5-1-2-13(9(16)12-5)8-6-7(15)10(3-14,18-8)4-17-6/h1-2,6-8,14-15H,3-4H2,(H2,11,12,16)/t6-,7+,8-,10+/m1/s1
Synonyms: LNA-C; Cytidine, 2'-O,4'-C-methylene-; 4-amino-1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2 2 1]heptan-3-yl]-1,2-dihydropyrimidin-2-one; (1S,3R,4R,7S)-7-hydroxy-1-hydroxymethyl-3-(cytosin-1-yl)-2,5-dioxabicyclo[2 2 1]heptane; 4-Amino-1-[2,5-anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-2(1H)-pyrimidinone

5-Methyl-2'-O,4'-C-methylenecytidine

Description: 5-Methyl-2'-O,4'-C-methylenecytidine, an intriguing nucleoside analog, emerges as a captivating specimen in combating viral adversaries. Showcasing robust antiviral prowess, it has garnered remarkable interest in the realm of scientific exploration. Elucidating its potential therapeutics, 5-Methyl-2'-O,4'-C-methylenecytidine manifests as a potent weapon against notorious afflictions such as hepatitis C and COVID-19. Distinctively, through its structural idiosyncrasies, it skillfully thwarts viral replication by impeding the viral RNA synthesis process.
CAT: BRP-00074
CAS: 847650-87-7
Molecular Formula: C11H15N3O5
Molecular Weight: 269.25
Purity: ≥95%
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Density: 1.84±0.1 g/cm3 (Predicted)
Boiling Point: 526.8±60.0°C (Predicted)
InChIKey: NELYIRACPIJATH-SZVQBCOZSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C3C(C(O2)(CO3)CO)O
IUPAC Name: 4-amino-1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylpyrimidin-2-one
InChI: InChI=1S/C11H15N3O5/c1-5-2-14(10(17)13-8(5)12)9-6-7(16)11(3-15,19-9)4-18-6/h2,6-7,9,15-16H,3-4H2,1H3,(H2,12,13,17)/t6-,7+,9-,11+/m1/s1
Synonyms: LNA-5MeC; 4-amino-1-[2,5-anhydro-4-(hydroxymethyl)-alpha-L-lyxofuranosyl]-5-methylcytosine; 4-amino-1-[2,5-anhydro-4-(hydroxymethyl)-alpha-L-lyxofuranosyl]-5-methylpyrimidin-2(1H)-one; 1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylcytosine; 2(1H)-Pyrimidinone, 4-amino-1-[2,5-anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-5-methyl-

3'-O-Methylcytidine

Description: 3'-O-Methylcytidine is an indispensable compound in the biomedical field, functioning as a cytidine analogue. This compound assumes a pivotal role as a fundamental constituent in producing nucleoside analog medications and research of viral agents.
CAT: BRP-00075
CAS: 20594-00-7
Molecular Formula: C10H15N3O5
Molecular Weight: 257.24
Purity: ≥95%
Appearance: White Powder
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Storage: Store at 2-8°C
Density: 1.7±0.1 g/cm3
Melting Point: 207-210°C
Boiling Point: 506.0±60.0°C at 760 mmHg
InChIKey: RZJCFLSPBDUNDH-ZOQUXTDFSA-N
Solubility: Soluble in Methanol (10 mg/mL)
CanonicalSMILES: COC1C(OC(C1O)N2C=CC(=NC2=O)N)CO
IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]pyrimidin-2-one
InChI: InChI=1S/C10H15N3O5/c1-17-8-5(4-14)18-9(7(8)15)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1
Synonyms: 3'-(O-Methyl) Cytidine; 3'-O-Methyl-D-cytidine; O3'-methyl-cytidine; O3'-Methylcytidine; 4-amino-1-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one

2-Amino-N2-O-methyladenosine

Description: 2-Amino-N2-O-methyladenosine, a remarkable biomedicine, emerges as an efficacious treatment for a diverse array of ailments. This multifaceted compound exhibits its prowess as a viable therapeutic intervention in the realm of malignancy through its remarkable capacity to impede neoplastic proliferation and instigate apoptotic demise. Moreover, in the domain of combating viral infections, it demonstrates immense potential by specifically antagonizing the viral replication mechanisms.
CAT: BRP-00076
CAS: 80791-87-3
Molecular Formula: C11H16N6O4
Molecular Weight: 296.29
Purity: ≥97%
Appearance: White to Off-white Powder
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Storage: Store at 2-8 °C, Keep in a dark and dry place
Density: 1.983 g/cm3
Melting Point: 121-122°C
Boiling Point: 733.177°C at 760 mmHg
InChIKey: JLWUWXCKSOIFPS-KQYNXXCUSA-N
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=C(N=C32)N)N)CO)O
IUPAC Name: (2R,3R,4R,5R)-5-(2,6-diaminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol
InChI: InChI=1S/C11H16N6O4/c1-20-7-6(19)4(2-18)21-10(7)17-3-14-5-8(12)15-11(13)16-9(5)17/h3-4,6-7,10,18-19H,2H2,1H3,(H4,12,13,15,16)/t4-,6-,7-,10-/m1/s1
Synonyms: 2-Amino-2'-O-methyladenosine; 2'-O-methyl-2,6-diaminopurine-riboside; (2R,3R,4R,5R)-5-(2,6-diamino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; 2-NH2-2'-O-Me-Ar

3'-O-(2-Methoxyethyl)adenosine

Description: 3'-O-(2-Methoxyethyl)adenosine, renowned in the biomedical industry, holds immense significance for a myriad of applications. With its pivotal role in the pharmaceutical realm, it contributes significantly in the combat against afflictions like cancer, viral infections, and inflammation. By orchestrating cellular pathways and regulating biological processes, this compound manifests promising therapeutic effects.
CAT: BRP-00079
CAS: 303197-30-0
Molecular Formula: C13H19N5O5
Molecular Weight: 325.32
Purity: ≥95%
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Density: 1.70±0.1 g/cm3
Boiling Point: 639.0±65.0 °C at 760 mmHg
InChIKey: RHVMAYVXDAXYHR-QYVSTXNMSA-N
Solubility: Soluble in DCM
CanonicalSMILES: COCCOC1C(OC(C1O)N2C=NC3=C(N=CN=C32)N)CO
IUPAC Name: (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol
InChI: InChI=1S/C13H19N5O5/c1-21-2-3-22-10-7(4-19)23-13(9(10)20)18-6-17-8-11(14)15-5-16-12(8)18/h5-7,9-10,13,19-20H,2-4H2,1H3,(H2,14,15,16)/t7-,9-,10-,13-/m1/s1
Synonyms: 3'-MOE-Adenosine; 3'-MOE-rA; Adenosine, 3'-O-(2-methoxyethyl)-; (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol

2'-O-Methyl-N2-isobutyroylguanosine

Description: 2'-O-Methyl-N2-isobutyroylguanosine is a biomedicine used in the reserch of certain diseases, including cancer. It acting as an antineoplastic compound and exhibiting potent activity against specific tumor cells. Its mechanism of action involves inhibiting cell growth and inducing apoptosis.
CAT: BRP-00080
CAS: 63264-29-9
Molecular Formula: C15H21N5O6
Molecular Weight: 367.36
Purity: ≥95%
Appearance: White to Light Yellow Powder
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Storage: Store at 2-8°C
Density: 1.68±0.10 g/cm3
InChIKey: RPULCYXEYODQOG-AKAIJSEGSA-N
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)OC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C15H21N5O6/c1-6(2)12(23)18-15-17-11-8(13(24)19-15)16-5-20(11)14-10(25-3)9(22)7(4-21)26-14/h5-7,9-10,14,21-22H,4H2,1-3H3,(H2,17,18,19,23,24)/t7-,9-,10-,14-/m1/s1
Synonyms: N2-Isobutyryl-2'-O-methylguanosine; N2-Isobutyryl-2'-O-methyl-D-guanosine; IBU-2'-OME-G; N2-isobutyryl-O2'-methyl-guanosine; N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; Guanosine, 2'-O-methyl-N-(2-methyl-1-oxopropyl)-; 2'-O-Methyl-N-(2-methyl-1-oxopropyl)guanosine

Arabinofuranosyl-guanine (ara-G)

Description: Arabinofuranosyl-guanine (ara-G) is an inhibitor of DNA synthesis used as an antimetabolic and antineoplastic agent.
CAT: BRP-00081
CAS: 38819-10-2
Molecular Formula: C10H13N5O5
Molecular Weight: 283.24
Purity: ≥98% by HPLC
Appearance: White to Off-white Solid
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Storage: Store at -20°C under inert atmosphere
Density: 2.25±0.1 g/cm3 (Predicted)
Melting Point: >245°C (dec.)
InChIKey: NYHBQMYGNKIUIF-FJFJXFQQSA-N
Solubility: Soluble in Aqueous Base (Slightly, Sonicated), DMSO (Slightly)
CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)NC(=NC2=O)N
IUPAC Name: 2-amino-9-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
InChI: InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6+,9-/m1/s1
Synonyms: Arabinosylguanine; 2-Amino-9-β-D-arabinofuranosyl-1,9-dihydro-6H-purin-6-one; 2-Amino-6-hydroxy-9-(β-D-arabinofuranosyl)purine; 9-β-D-Arabinofuranosylguanine; Araguanosine; Guanine arabinoside; NSC 76352; ara-Guanosine; A 4233; Arabinoguanosine

N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine

Description: N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine, an indispensable compound in the biomedical sector, showcases immense potential for therapeutic applications. Its remarkable chemical structure renders it uniquely suited for drug design, thereby paving the way for promising advancements in biomedicine. Widely employed in the pharmaceutical industry, this product plays a pivotal role in the development of medications targeting diverse ailments including cancer and viral infections.
CAT: BRP-00083
CAS: 333335-93-6
Molecular Formula: C20H23N5O6
Molecular Weight: 429.43
Purity: ≥95%
Appearance: White, off-white to faint yellow powder
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Storage: Store at 2-8 °C, Keep in a dark and dry place
Density: 1.5±0.0 g/cm3
InChIKey: RUFJMCSVNNGZFB-KHTYJDQRSA-N
CanonicalSMILES: COCCOC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O
IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C20H23N5O6/c1-29-7-8-30-16-15(27)13(9-26)31-20(16)25-11-23-14-17(21-10-22-18(14)25)24-19(28)12-5-3-2-4-6-12/h2-6,10-11,13,15-16,20,26-27H,7-9H2,1H3,(H,21,22,24,28)/t13-,15-,16-,20-/m1/s1
Synonyms: N-Benzoyl-2'-O-(2-methoxyethyl)adenosine; 2'-O-methoxyethyl-N6-benzoyl-adenosine; N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; N6-Bz-2'-O-MOE-A; N6-benzoyl-2'-O-methoxyethyl-adenosine
* Only for research. Not suitable for any diagnostic or therapeutic use.
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