Nucleosides - RNA / BOC Sciences

N6-Cyclopentyl-adenosine

Description: N6-Cyclopentyl-adenosine (CPA) - an adenosine analog and A1 adenosine receptor agonist - is pivotal in biomedicine as a research tool to inspect the part played by the adenosine receptor in distinct physiological processes. It also has potential therapeutic benefits that range from treating ischemia-reperfusion injuries to chronic pain.

CAT: BRP-00062

CAS: 41552-82-3

MF: C15H21N5O4

MF: 335.36

Purity: ≥95% by HPLC

Appearance: White to off-white solid

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Storage: Store at 2-8 °C

Density: 1.78±0.1 g/cm3 (Predicted)

Melting Point: 78.8 °C

Boiling Point: 673.4±65.0 °C at 760 mmHg

Application: Purinergic P1 Receptor Agonists

InChIKey: SQMWSBKSHWARHU-SDBHATRESA-N

Solubility: Soluble in Water

CanonicalSMILES: C1CCC(C1)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O

IUPAC Name: (2R,3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1

Synonyms: N6-Cyclopentyladenosine; CPA; N-Cyclopentyladenosine; UK 80882; (2R,3R,4S,5R)-2-[6-(Cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

4'-Fluorouridine

Description: 4'-Fluorouridine is an orally active RdRp inhibitor. It effectively blocks the replication of RSV and SARS-CoV-2.

CAT: BRP-00063

CAS: 1613589-24-4

MF: C9H11FN2O6

MF: 262.19

Purity: 98%

Appearance: Solid

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Density: 1.77±0.1 g/cm3

InChIKey: RDCYLPRXPILMRP-JVZYCSMKSA-N

CanonicalSMILES: O=C1NC(N([C@@H]2O[C@@](CO)(F)[C@@H](O)[C@H]2O)C=C1)=O

IUPAC Name: 1-[(2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H11FN2O6/c10-9(3-13)6(16)5(15)7(18-9)12-2-1-4(14)11-8(12)17/h1-2,5-7,13,15-16H,3H2,(H,11,14,17)/t5-,6+,7-,9-/m1/s1

Synonyms: 4'-fluorouridine;1613589-24-4;4'-C-Fluoro-uridine;1-[(2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione;1613591-91-5;SCHEMBL6839661;RDCYLPRXPILMRP-JVZYCSMKSA-N;AMY30709;EX-A6732;DA-70078;MS-23688;4'-fluorouridine (4'-FlU, EIDD-2749)?;1-((2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione;

3'-O-Methyluridine

Description: 3'-O-Methyluridine is a potent compound, serving as a therapeutic intervention for research of diverse viral infections and autoimmune conditions. Through its exceptional anti-replication properties, this remarkable compound effectively hampers viral proliferation.

CAT: BRP-00064

CAS: 6038-59-1

MF: C10H14N2O6

MF: 258.23

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at -20°C

Density: 1.53±0.1 g/cm3

Melting Point: 142-145°C

InChIKey: YKNATSNMFLEFRB-ZOQUXTDFSA-N

CanonicalSMILES: COC1C(OC(C1O)N2C=CC(=O)NC2=O)CO

IUPAC Name: 1-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C10H14N2O6/c1-17-8-5(4-13)18-9(7(8)15)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,9-/m1/s1

Synonyms: 3'-O-Methyl-D-uridine; O3'-methyl-uridine; 1-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 3'-O-Me-Ur; 3'-O-methyl-uridine; 3'-(O-Methyl) Uridine

3'-O-Methyladenosine

Description: 3'-O-Methyladenosine, an indispensable biomolecule utilized in the realm of biomedical research, assumes a pivotal role in the meticulous exploration of RNA modifications. Ubiquitously present within a myriad of RNA molecules, this compound exerts profound influence on gene expression regulation, cellular signaling, and the genesis of diseases.

CAT: BRP-00065

CAS: 10300-22-8

MF: C11H15N5O4

MF: 281.27

Purity: ≥95%

Appearance: White Powder

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Storage: Store at -20°C

Density: 1.84±0.1 g/cm3(Predicted)

Melting Point: 177-178 °C

Boiling Point: 623.8±65.0 °C(Predicted)

InChIKey: RYAFZRROCNNRFK-IOSLPCCCSA-N

Solubility: Soluble in Methanol (10 mg/mL)

CanonicalSMILES: COC1C(OC(C1O)N2C=NC3=C(N=CN=C32)N)CO

IUPAC Name: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-methoxyoxolan-3-ol

InChI: InChI=1S/C11H15N5O4/c1-19-8-5(2-17)20-11(7(8)18)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1

Synonyms: 3'-O-Methyl-D-adenosine; (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; NSC 103062; 3'-O-Methyl Adenosine; 3'-(O-Methyl) Adenosine

2'-O-Methyladenosine

Description: 2'-O-Methyladenosine is a modified nucleoside where a methyl group is attached to the 2' hydroxyl of the ribose sugar. This modification enhances the stability and binding affinity of RNA molecules, making it valuable in research focused on RNA structure, function, and therapeutic development. It is commonly used in the synthesis of chemically modified RNA for studies in molecular biology and biotechnology.

CAT: BRP-00066

CAS: 2140-79-6

MF: C11H15N5O4

MF: 281.27

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at 2-8°C

Density: 1.84±0.1 g/cm3 (Predicted)

Melting Point: 198-200°C

Boiling Point: 623.8±65.0°C (Predicted)

Symbol: Am

InChIKey: FPUGCISOLXNPPC-IOSLPCCCSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated, Sonicated), Water (Slightly)

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol

InChI: InChI=1S/C11H15N5O4/c1-19-8-7(18)5(2-17)20-11(8)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1

Synonyms: Adenosine, 2'-O-methyl-; (2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; Cordysinin B; 2'-O-Methyl-D-adenosine; 2'-O-Me-adenosine; 2'-(O-Methyl) Adenosine; 2'-O-Me-Ado

N6-Benzoyl-2'-O-methyladenosine

Description: N6-Benzoyl-2'-O-methyladenosine is an indispensable compound in the realm of biomedical research assuming a paramount role in the exploration of RNA modifications and epigenetics.

CAT: BRP-00067

CAS: 85079-00-1

MF: C18H19N5O5

MF: 385.37

Purity: ≥95%

Appearance: Off-white to Pale Yellow Powder

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Storage: Store at RT

Density: 1.59±0.1 g/cm3 (Predicted)

InChIKey: PHFHSPQCDRKMQJ-XWXWGSFUSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O

IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C18H19N5O5/c1-27-14-13(25)11(7-24)28-18(14)23-9-21-12-15(19-8-20-16(12)23)22-17(26)10-5-3-2-4-6-10/h2-6,8-9,11,13-14,18,24-25H,7H2,1H3,(H,19,20,22,26)/t11-,13-,14-,18-/m1/s1

Synonyms: N6-Benzoyl-2'-O-methyl-D-adenosine; Bz-2'-OMe-A; N-Benzoyl-2'-O-methyladenosine; N6-Benzoyl-2'-O-methyl-adenosine; 2'-O-methyl-N6-benzoyladenosine; N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; N6-Bz-2'-OMe-A; N6-Bz-2'-O-Me-Ar

N2-Isobutyryl-2'-O,4'-C-methyleneguanosine

Description: N2-Isobutyryl-2'-O,4'-C-methyleneguanosine is a potent antiviral compound used in the biomedical industry. It exhibits inhibitory activity against RNA viruses like Dengue and Zika viruses. This compound blocks viral replication by interfering with viral RNA synthesis. Its unique chemical structure makes it a valuable tool in antiviral drug discovery and development.

CAT: BRP-00069

CAS: 206055-68-7

MF: C15H19N5O6

MF: 365.34

Purity: ≥95%

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Density: 1.87±0.1 g/cm3

Melting Point: 196-199 °C

InChIKey: FUKSKECTPBMMEQ-BQOLRUCTSA-N

Solubility: Soluble in Water

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C4C(C(O3)(CO4)CO)O

IUPAC Name: N-[9-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C15H19N5O6/c1-6(2)11(23)18-14-17-10-7(12(24)19-14)16-5-20(10)13-8-9(22)15(3-21,26-13)4-25-8/h5-6,8-9,13,21-22H,3-4H2,1-2H3,(H2,17,18,19,23,24)/t8-,9+,13-,15+/m1/s1

Synonyms: guanosine, 2'-O,4'-C-methylene-N-(2-methyl-1-oxopropyl)-; (1S,3R,4R,7S)-7-Hydroxy-1-hydroxymethyl-3-(2-N-isobutyrylguanin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane; N-[6,9-Dihydro-6-oxo-9-[(1S,3R,4R,7S)-1-(hydroxymethyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptane-3-yl]-1H-purine-2-yl]isobutyramide

2'-O,4'-C-Methyleneuridine

Description: 2'-O,4'-C-Methyleneuridine, a biomedical compound, plays a pivotal role in the advancement of antiviral drugs and therapeutics. Its profound efficacy against a wide array of viral infections, namely hepatitis C virus (HCV) and respiratory syncytial virus (RSV), unveils its tremendous potential in combatting viral diseases.

CAT: BRP-00070

CAS: 200435-92-3

MF: C10H12N2O6

MF: 256.21

Purity: ≥95%

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Storage: Store at -20 °C

Density: 1.695 g/cm3

Melting Point: 239-243°C (methanol)

InChIKey: KNLNWXXWKDEEFW-JIOCBJNQSA-N

Solubility: Soluble in Methanol

CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=CC(=O)NC3=O)O)CO

IUPAC Name: 1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C10H12N2O6/c13-3-10-4-17-6(7(10)15)8(18-10)12-2-1-5(14)11-9(12)16/h1-2,6-8,13,15H,3-4H2,(H,11,14,16)/t6-,7+,8-,10+/m1/s1

Synonyms: 1-(2-O,4-C-Methylene-beta-D-ribofuranosyl)uracil; LNA-U; 1-[2,5-Anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-2,4(1H,3H)-pyrimidinedione; (1S,3R,4R,7S)-7-Hydroxy-1-hydroxymethyl-3-(uracil-1-yl)-2,5-dioxabicyclo-[2.2.1]heptane

5-Methyl-2'-O,4'-C-methyleneuridine

Description: 5-Methyl-2'-O,4'-C-methyleneuridine is a chemically modified nucleoside where a methylene bridge connects the 2'-oxygen and 4'-carbon of the ribose sugar, and the uridine base is methylated at the 5-position. This modification enhances the stability and binding affinity of RNA molecules, making it valuable in RNA research and therapeutic applications. It is often used to study RNA structure, function, and interactions, and in the development of novel RNA-based drugs.

CAT: BRP-00071

CAS: 206055-67-6

MF: C11H14N2O6

MF: 270.24

Purity: ≥95%

Appearance: White to light brown powder

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Storage: Store at 2-8 °C

Density: 1.598±0.1 g/cm³ (Predicted)

Melting Point: 196-198 °C

InChIKey: TYYUAZVXLRMUMN-SZVQBCOZSA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C3C(C(O2)(CO3)CO)O

IUPAC Name: 1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C11H14N2O6/c1-5-2-13(10(17)12-8(5)16)9-6-7(15)11(3-14,19-9)4-18-6/h2,6-7,9,14-15H,3-4H2,1H3,(H,12,16,17)/t6-,7+,9-,11+/m1/s1

Synonyms: LNA-5MeU; 1-[(1S,3R,4R,7S)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)thymine; 1-[2,5-Anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione

2'-O,4'-C-Methyleneadenosine

Description: 2'-O,4'-C-Methyleneadenosine is a highly versatile compound, skillfully inhibiting the replication of malignant cells and viruses to effectively disrupts the pathogenic cascade.

CAT: BRP-00072

CAS: 206055-70-1

MF: C11H13N5O4

MF: 279.25

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at 2-8°C

Density: 2.14±0.1 g/cm3

Melting Point: 267-270°C

Boiling Point: 660.0±65.0°C at 760 mmHg

Shelf Life: >2 years if stored properly

InChIKey: GHKDRNDFVCEETA-KYAGDKKUSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=NC4=C(N=CN=C43)N)O)CO

IUPAC Name: (1S,3R,4R,7S)-3-(6-aminopurin-9-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-ol

InChI: InChI=1S/C11H13N5O4/c12-8-5-9(14-3-13-8)16(4-15-5)10-6-7(18)11(1-17,20-10)2-19-6/h3-4,6-7,10,17-18H,1-2H2,(H2,12,13,14)/t6-,7+,10-,11+/m1/s1

Synonyms: (1S,3R,4R,7S)-3-(6-amino-9H-purin-9-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-ol; LNA-Adenosine; (1S,3R,4R,7S)-7-Hydroxy-1-hydroxymethyl-3-(adenin-9-yl)-2,5-dioxabicyclo-[2.2.1]heptane; 9H-Purin-6-amine, 9-[2,5-anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-; 9-[2,5-Anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-9H-purin-6-amine; LNA-A diol; 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)adenine; LNA-A

2'-O,4'-C-Methylenecytidine

Description: 2'-O,4'-C-Methylenecytidine is a highly imperative compound in the field of compound, finding its application in the development of antiviral medications. Underpinning its significance, this exquisite compound assuming a pivotal role in impeding viral replication dynamics.

CAT: BRP-00073

CAS: 206055-69-8

MF: C10H13N3O5

MF: 255.23

Purity: ≥95%

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Density: 2.0±0.1 g/cm3

Melting Point: 274-276 °C

Boiling Point: 532.9±60.0°C at 760 mmHg

InChIKey: FCMRQQIZHFHCNG-JIOCBJNQSA-N

CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=CC(=NC3=O)N)O)CO

IUPAC Name: 4-amino-1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]pyrimidin-2-one

InChI: InChI=1S/C10H13N3O5/c11-5-1-2-13(9(16)12-5)8-6-7(15)10(3-14,18-8)4-17-6/h1-2,6-8,14-15H,3-4H2,(H2,11,12,16)/t6-,7+,8-,10+/m1/s1

Synonyms: LNA-C; Cytidine, 2'-O,4'-C-methylene-; 4-amino-1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2 2 1]heptan-3-yl]-1,2-dihydropyrimidin-2-one; (1S,3R,4R,7S)-7-hydroxy-1-hydroxymethyl-3-(cytosin-1-yl)-2,5-dioxabicyclo[2 2 1]heptane; 4-Amino-1-[2,5-anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-2(1H)-pyrimidinone

5-Methyl-2'-O,4'-C-methylenecytidine

Description: 5-Methyl-2'-O,4'-C-methylenecytidine, an intriguing nucleoside analog, emerges as a captivating specimen in combating viral adversaries. Showcasing robust antiviral prowess, it has garnered remarkable interest in the realm of scientific exploration. Elucidating its potential therapeutics, 5-Methyl-2'-O,4'-C-methylenecytidine manifests as a potent weapon against notorious afflictions such as hepatitis C and COVID-19. Distinctively, through its structural idiosyncrasies, it skillfully thwarts viral replication by impeding the viral RNA synthesis process.

CAT: BRP-00074

CAS: 847650-87-7

MF: C11H15N3O5

MF: 269.25

Purity: ≥95%

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Density: 1.84±0.1 g/cm3 (Predicted)

Boiling Point: 526.8±60.0°C (Predicted)

InChIKey: NELYIRACPIJATH-SZVQBCOZSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C3C(C(O2)(CO3)CO)O

IUPAC Name: 4-amino-1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylpyrimidin-2-one

InChI: InChI=1S/C11H15N3O5/c1-5-2-14(10(17)13-8(5)12)9-6-7(16)11(3-15,19-9)4-18-6/h2,6-7,9,15-16H,3-4H2,1H3,(H2,12,13,17)/t6-,7+,9-,11+/m1/s1

Synonyms: LNA-5MeC; 4-amino-1-[2,5-anhydro-4-(hydroxymethyl)-alpha-L-lyxofuranosyl]-5-methylcytosine; 4-amino-1-[2,5-anhydro-4-(hydroxymethyl)-alpha-L-lyxofuranosyl]-5-methylpyrimidin-2(1H)-one; 1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylcytosine; 2(1H)-Pyrimidinone, 4-amino-1-[2,5-anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-5-methyl-

3'-O-Methylcytidine

Description: 3'-O-Methylcytidine is an indispensable compound in the biomedical field, functioning as a cytidine analogue. This compound assumes a pivotal role as a fundamental constituent in producing nucleoside analog medications and research of viral agents.

CAT: BRP-00075

CAS: 20594-00-7

MF: C10H15N3O5

MF: 257.24

Purity: ≥95%

Appearance: White Powder

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Storage: Store at 2-8°C

Density: 1.7±0.1 g/cm3

Melting Point: 207-210°C

Boiling Point: 506.0±60.0°C at 760 mmHg

InChIKey: RZJCFLSPBDUNDH-ZOQUXTDFSA-N

Solubility: Soluble in Methanol (10 mg/mL)

CanonicalSMILES: COC1C(OC(C1O)N2C=CC(=NC2=O)N)CO

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C10H15N3O5/c1-17-8-5(4-14)18-9(7(8)15)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1

Synonyms: 3'-(O-Methyl) Cytidine; 3'-O-Methyl-D-cytidine; O3'-methyl-cytidine; O3'-Methylcytidine; 4-amino-1-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one

2-Amino-N2-O-methyladenosine

Description: 2-Amino-N2-O-methyladenosine, a remarkable biomedicine, emerges as an efficacious treatment for a diverse array of ailments. This multifaceted compound exhibits its prowess as a viable therapeutic intervention in the realm of malignancy through its remarkable capacity to impede neoplastic proliferation and instigate apoptotic demise. Moreover, in the domain of combating viral infections, it demonstrates immense potential by specifically antagonizing the viral replication mechanisms.

CAT: BRP-00076

CAS: 80791-87-3

MF: C11H16N6O4

MF: 296.29

Purity: ≥97%

Appearance: White to Off-white Powder

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Storage: Store at 2-8 °C, Keep in a dark and dry place

Density: 1.983 g/cm3

Melting Point: 121-122°C

Boiling Point: 733.177°C at 760 mmHg

InChIKey: JLWUWXCKSOIFPS-KQYNXXCUSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=C(N=C32)N)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(2,6-diaminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol

InChI: InChI=1S/C11H16N6O4/c1-20-7-6(19)4(2-18)21-10(7)17-3-14-5-8(12)15-11(13)16-9(5)17/h3-4,6-7,10,18-19H,2H2,1H3,(H4,12,13,15,16)/t4-,6-,7-,10-/m1/s1

Synonyms: 2-Amino-2'-O-methyladenosine; 2'-O-methyl-2,6-diaminopurine-riboside; (2R,3R,4R,5R)-5-(2,6-diamino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; 2-NH2-2'-O-Me-Ar

3'-O-(2-Methoxyethyl)adenosine

Description: 3'-O-(2-Methoxyethyl)adenosine, renowned in the biomedical industry, holds immense significance for a myriad of applications. With its pivotal role in the pharmaceutical realm, it contributes significantly in the combat against afflictions like cancer, viral infections, and inflammation. By orchestrating cellular pathways and regulating biological processes, this compound manifests promising therapeutic effects.

CAT: BRP-00079

CAS: 303197-30-0

MF: C13H19N5O5

MF: 325.32

Purity: ≥95%

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Density: 1.70±0.1 g/cm3

Boiling Point: 639.0±65.0 °C at 760 mmHg

InChIKey: RHVMAYVXDAXYHR-QYVSTXNMSA-N

Solubility: Soluble in DCM

CanonicalSMILES: COCCOC1C(OC(C1O)N2C=NC3=C(N=CN=C32)N)CO

IUPAC Name: (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol

InChI: InChI=1S/C13H19N5O5/c1-21-2-3-22-10-7(4-19)23-13(9(10)20)18-6-17-8-11(14)15-5-16-12(8)18/h5-7,9-10,13,19-20H,2-4H2,1H3,(H2,14,15,16)/t7-,9-,10-,13-/m1/s1

Synonyms: 3'-MOE-Adenosine; 3'-MOE-rA; Adenosine, 3'-O-(2-methoxyethyl)-; (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol

2'-O-Methyl-N2-isobutyroylguanosine

Description: 2'-O-Methyl-N2-isobutyroylguanosine is a biomedicine used in the reserch of certain diseases, including cancer. It acting as an antineoplastic compound and exhibiting potent activity against specific tumor cells. Its mechanism of action involves inhibiting cell growth and inducing apoptosis.

CAT: BRP-00080

CAS: 63264-29-9

MF: C15H21N5O6

MF: 367.36

Purity: ≥95%

Appearance: White to Light Yellow Powder

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Storage: Store at 2-8°C

Density: 1.68±0.10 g/cm3

InChIKey: RPULCYXEYODQOG-AKAIJSEGSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)OC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C15H21N5O6/c1-6(2)12(23)18-15-17-11-8(13(24)19-15)16-5-20(11)14-10(25-3)9(22)7(4-21)26-14/h5-7,9-10,14,21-22H,4H2,1-3H3,(H2,17,18,19,23,24)/t7-,9-,10-,14-/m1/s1

Synonyms: N2-Isobutyryl-2'-O-methylguanosine; N2-Isobutyryl-2'-O-methyl-D-guanosine; IBU-2'-OME-G; N2-isobutyryl-O2'-methyl-guanosine; N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; Guanosine, 2'-O-methyl-N-(2-methyl-1-oxopropyl)-; 2'-O-Methyl-N-(2-methyl-1-oxopropyl)guanosine

Arabinofuranosyl-guanine (ara-G)

Description: Arabinofuranosyl-guanine (ara-G) is an inhibitor of DNA synthesis used as an antimetabolic and antineoplastic agent.

CAT: BRP-00081

CAS: 38819-10-2

MF: C10H13N5O5

MF: 283.24

Purity: ≥98% by HPLC

Appearance: White to Off-white Solid

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Storage: Store at -20°C under inert atmosphere

Density: 2.25±0.1 g/cm3 (Predicted)

Melting Point: >245°C (dec.)

InChIKey: NYHBQMYGNKIUIF-FJFJXFQQSA-N

Solubility: Soluble in Aqueous Base (Slightly, Sonicated), DMSO (Slightly)

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)NC(=NC2=O)N

IUPAC Name: 2-amino-9-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6+,9-/m1/s1

Synonyms: Arabinosylguanine; 2-Amino-9-β-D-arabinofuranosyl-1,9-dihydro-6H-purin-6-one; 2-Amino-6-hydroxy-9-(β-D-arabinofuranosyl)purine; 9-β-D-Arabinofuranosylguanine; Araguanosine; Guanine arabinoside; NSC 76352; ara-Guanosine; A 4233; Arabinoguanosine

N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine

Description: N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine, an indispensable compound in the biomedical sector, showcases immense potential for therapeutic applications. Its remarkable chemical structure renders it uniquely suited for drug design, thereby paving the way for promising advancements in biomedicine. Widely employed in the pharmaceutical industry, this product plays a pivotal role in the development of medications targeting diverse ailments including cancer and viral infections.

CAT: BRP-00083

CAS: 333335-93-6

MF: C20H23N5O6

MF: 429.43

Purity: ≥95%

Appearance: White, off-white to faint yellow powder

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Storage: Store at 2-8 °C, Keep in a dark and dry place

Density: 1.5±0.0 g/cm3

InChIKey: RUFJMCSVNNGZFB-KHTYJDQRSA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O

IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C20H23N5O6/c1-29-7-8-30-16-15(27)13(9-26)31-20(16)25-11-23-14-17(21-10-22-18(14)25)24-19(28)12-5-3-2-4-6-12/h2-6,10-11,13,15-16,20,26-27H,7-9H2,1H3,(H,21,22,24,28)/t13-,15-,16-,20-/m1/s1

Synonyms: N-Benzoyl-2'-O-(2-methoxyethyl)adenosine; 2'-O-methoxyethyl-N6-benzoyl-adenosine; N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; N6-Bz-2'-O-MOE-A; N6-benzoyl-2'-O-methoxyethyl-adenosine

2'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N4-acetylcytidine

Description: It is used for nucleoside modification and nucleic acid synthesis.

CAT: BRP-00086

CAS: 121058-85-3

MF: C38H47N3O8Si

MF: 701.88

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

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Storage: Store at 2-8°C

Density: 1.19±0.1 g/cm3 (Predicted)

InChIKey: ZFRWPAYPCFTQHK-HYGOWAQNSA-N

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)O[Si](C)(C)C(C)(C)C

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C38H47N3O8Si/c1-25(42)39-32-22-23-41(36(44)40-32)35-34(49-50(7,8)37(2,3)4)33(43)31(48-35)24-47-38(26-12-10-9-11-13-26,27-14-18-29(45-5)19-15-27)28-16-20-30(46-6)21-17-28/h9-23,31,33-35,43H,24H2,1-8H3,(H,39,40,42,44)/t31-,33-,34-,35-/m1/s1

Synonyms: 2'-O-TBDMS-5'-O-DMT-N4-Ac cytidine; N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine; N4-acetyl-2'-O-(t-butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)cytidine; 5'-O-(4,4'-Dimethoxytrityl) 2'-O-[(1,1-dimethylethyl)-dimethylsilyl]-N4-acetylcytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine; N4-Ac-2'-O-TBDMS-5'-O-DMT-C; N4-Ac-DMT-2'-O-TBDMS-Cr; N4-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-cytidine; 5'-DMT-2'-tBDSilyl Cytidine (n-acetyl)

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine

Description: 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine, an indispensable compound utilized in the biomedical sector, showcases immense promise in combatting a plethora of diseases and disorders, namely cancer and viral infections. Its extraordinary configuration empowers it to disrupt replication procedures, rendering it a highly efficacious agent against antiviral and anticancer fronts.

CAT: BRP-00087

CAS: 81279-39-2

MF: C41H51N5O8Si

MF: 769.96

Purity: ≥95%

Appearance: White powder

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Storage: Store at -20 °C

Density: 1.3±0.1 g/cm3

InChIKey: JMCNKJFOIJGYRG-CJEGOSRCSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)O[Si](C)(C)C(C)(C)C

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C41H51N5O8Si/c1-25(2)36(48)44-39-43-35-32(37(49)45-39)42-24-46(35)38-34(54-55(8,9)40(3,4)5)33(47)31(53-38)23-52-41(26-13-11-10-12-14-26,27-15-19-29(50-6)20-16-27)28-17-21-30(51-7)22-18-28/h10-22,24-25,31,33-34,38,47H,23H2,1-9H3,(H2,43,44,45,48,49)/t31-,33-,34-,38-/m1/s1

Synonyms: N2-iBu-2'-O-TBDMS-5'-O-DMT-G; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine; N2-iBu-DMT-2'-O-TBDMS-Gr; N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-guanosine; 5'-DMT-2'-tBDSilyl Guanosine (n-ibu)