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Nucleosides

2'-Modified Nucleosides
(334/334)
3'-Modified Nucleosides
(175/175)
5'-Modified Nucleosides
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Anhydro-Nucleosides
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Arabinonucleosides
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Base Protected Nucleosides
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Halogen Nucleosides
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Ribonucleosides
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5-Methoxycarbonylmethyl-2'-O-methyluridine (BRP-02136)

5-Methoxycarbonylmethyl-2'-O-methyluridine (BRP-02136)

Description: 5-Methoxycarbonylmethyl-2'-O-methyluridine, an indispensable biomedical compound, is extensively employed in the realm of research and development for antiviral drugs. This multifaceted compound assumes a paramount role in tackling diverse viral infections, meticulously targeting distinctive RNA viruses. Its eminent significance stems from its peculiar chemical structure which confers it with the potential to exhibit vigorous antiviral activity, hindering viral replication.
CAT: BRP-02136
CAS: 60197-31-1
Molecular Formula: C13H18N2O8
Molecular Weight: 330.29
Purity: ≥95%
Appearance: White to Off-white Solid
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5 mg $599 In stock
20 mg $990 In stock
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Storage: Store at 2-8 °C
Density: 1.50±0.1 g/cm3
Symbol: mcm5Um
InChIKey: XOTXNXXJZCFUOA-UGKPPGOTSA-N
SMILES: COC1C(C(OC1N2C=C(C(=O)NC2=O)CC(=O)OC)CO)O
IUPAC Name: methyl 2-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]acetate
InChI: InChI=1S/C13H18N2O8/c1-21-8(17)3-6-4-15(13(20)14-11(6)19)12-10(22-2)9(18)7(5-16)23-12/h4,7,9-10,12,16,18H,3,5H2,1-2H3,(H,14,19,20)/t7-,9-,10-,12-/m1/s1
Synonyms: 5-(Methoxycarbonyl)methyl-2'-O-Methyl uridine; (2-OMe-MCM5U); 2'-O-Methyluridine 5-acetic acid methyl ester; 1,2,3,4-Tetrahydro-1-(2-O-methyl-beta-D-ribofuranosyl)-2,4-dioxo-5-pyrimidineacetic acid methyl ester; 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-1-(2-O-methyl-b-D-ribofuranosyl)-2,4-dioxo-, methyl ester; Methyl 2-(1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetate
1-Methyladenosine (BRP-02149)

1-Methyladenosine (BRP-02149)

Description: 1-Methyladenosine is a modified nucleoside often found in tRNAs and rRNA. In the biomedical industry, it is pivotal for protein synthesis, cellular function, and responses to stressors. It's also being studied concerning viral RNA methylation in diseases such as hepatitis C.
CAT: BRP-02149
CAS: 15763-06-1
Molecular Formula: C11H15N5O4
Molecular Weight: 281.27
Purity: ≥95%
Appearance: White to Off-white Crystalline Powder
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500 mg $257 In stock
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Storage: Store at -20 °C, under inert atmosphere
Density: 1.88±0.1 g/cm3
Melting Point: >217 °C (dec.)
Boiling Point: 655.4±65.0 °C at 760 mmHg
Symbol: m1A
InChIKey: GFYLSDSUCHVORB-IOSLPCCCSA-N
Solubility: Soluble in DMSO (Slightly), Water (Slightly, Sonicated)
SMILES: CN1C=NC2=C(C1=N)N=CN2C3C(C(C(O3)CO)O)O
IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methylpurin-9-yl)oxolane-3,4-diol
InChI: InChI=1S/C11H15N5O4/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11-12,17-19H,2H2,1H3/t5-,7-,8-,11-/m1/s1
Synonyms: Adenosine, 1-methyl-; N1-Methyladenosine; N1-Methyl-D-adenosine; NSC 92165; (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)tetrahydrofuran-3,4-diol; Adenosine, N,6-didehydro-1,9-dihydro-1-methyl-
2'-O-Methylguanosine (BRP-00011)

2'-O-Methylguanosine

Description: It is a guanine nucleoside analogue that is used to prepare nucleoside derivatives as inhibitors of RNA-dependent RNA virus polymerases.
CAT: BRP-00011
CAS: 2140-71-8
Molecular Formula: C11H15N5O5
Molecular Weight: 297.27
Purity: ≥95%
Appearance: White to Off-white Solid
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Storage: Store at 2-8°C
Density: 1.98±0.1 g/cm3 (Predicted)
Melting Point: >216°C (dec.)
Boiling Point: 711.7°C at 760 mmHg
Symbol: Gm
InChIKey: OVYNGSFVYRPRCG-KQYNXXCUSA-N
Solubility: Soluble in Aqueous Base (Slightly), DMSO (Slightly)
SMILES: COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O
IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1H-purin-6-one
InChI: InChI=1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1
Synonyms: 2'-(O-Methyl) Guanosine; Guanosine, 2'-O-methyl-; 2'-O-Methyl Guanosine; O2'-Methylguanosine; 2-amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-amino-9-(2-O-methyl-beta-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one
2'-O-Methyl-5-methylcytidine (BRP-00013)

2'-O-Methyl-5-methylcytidine

Description: 2'-O-Methyl-5-methylcytidine is a biomedical compound unveiling powerful antiviral potential. It can effectively thwart their nefarious RNA enhancement machinery, thus abruptly halting their audacious replication endeavors.
CAT: BRP-00013
CAS: 113886-70-7
Molecular Formula: C11H17N3O5
Molecular Weight: 271.27
Purity: ≥95%
Appearance: White to Off-white Crystalline Powder
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Storage: Store at 2-8°C
Density: 1.61±0.1 g/cm3(Predicted)
Melting Point: 235-238°C
Boiling Point: 504.6±60.0 °C(Predicted)
Symbol: m5Cm
InChIKey: CNVRVGAACYEOQI-FDDDBJFASA-N
Solubility: Soluble in DMSO (Slightly), Water (Slightly, Sonicated)
SMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)OC
IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-5-methylpyrimidin-2-one
InChI: InChI=1S/C11H17N3O5/c1-5-3-14(11(17)13-9(5)12)10-8(18-2)7(16)6(4-15)19-10/h3,6-8,10,15-16H,4H2,1-2H3,(H2,12,13,17)/t6-,7-,8-,10-/m1/s1
Synonyms: 2'-(O-Methyl)-5-Methyl Cytidine; 5,2'-O-dimethylcytidine; Cytidine, 5-methyl-2'-O-methyl-; 5-methyl-2'-O-methylcytidine; 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one
5-Iodotubercidin (BRP-00017)

5-Iodotubercidin

Description: It is an adenosine kinase inhibitor, protein kinase inhibitor and activator, nucleoside transporter inhibitor.
CAT: BRP-00017
CAS: 24386-93-4
Molecular Formula: C11H13IN4O4
Molecular Weight: 392.15
Purity: ≥95%
Appearance: Off-white to Light Brown Solid
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Storage: Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -113°C for long term (months to years).
Density: 2.49 g/cm3
Melting Point: 216-217°C (dec.)
Boiling Point: 701.5±60.0 °C | Condition: Press: 760 Torr
Application: An analogue of the antibiotic tubercidin, a pyrrolo[2,3-d]pyrimidine nucleoside antibiotic. A potent inhibitor of adenosine kinase from rat or guinea pig brain. Inhibits uptake of 3H-adenosine into brain slices.
Shelf Life: 2 years
InChIKey: WHSIXKUPQCKWBY-IOSLPCCCSA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated)
SMILES: C1=C(C2=C(N1C3C(C(C(O3)CO)O)O)N=CN=C2N)I
IUPAC Name: (2R,3R,4S,5R)-2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChI: InChI=1S/C11H13IN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1
Synonyms: 7-Iodo-tubercidin; 7-Deaza-7-iodoadenosine; 4-Amino-5-iodo-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine; NSC 113939; 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 7-iodo-7-deazaadenosine; 7-deaza-7-I-Ar
5-Iodocytidine (BRP-00019)

5-Iodocytidine

Description: 5-Iodocytidine is an intermediate for research in the field of nucleic acids and nucleic acid-protein interactions.
CAT: BRP-00019
CAS: 1147-23-5
Molecular Formula: C9H12IN3O5
Molecular Weight: 369.11
Purity: ≥95%
Appearance: White solid
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Storage: Store at -20 °C
Density: 2.52±0.1 g/cm3 (Predicted)
Melting Point: >160 °C (dec.)
Boiling Point: 565.5±60.0 °C at 760 mmHg
InChIKey: LQQGJDJXUSAEMZ-UAKXSSHOSA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)
SMILES: C1=C(C(=NC(=O)N1C2C(C(C(O2)CO)O)O)N)I
IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one
InChI: InChI=1S/C9H12IN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1
Synonyms: 1-β-D-Ribofuranosyl-5-iodocytosine; 5-Iodo-cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; 5-Iodo-ribo Cytidine
5-Iodouridine (BRP-00020)

5-Iodouridine

Description: It is a Rho-GTPase cell protein inhibitor.
CAT: BRP-00020
CAS: 1024-99-3
Molecular Formula: C9H11IN2O6
Molecular Weight: 370.10
Purity: ≥95%
Appearance: White Powder
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Storage: Store at 2-8°C
Density: 2.27±0.1 g/cm3 (Predicted)
Melting Point: 205-207°C (dec.)
InChIKey: RKSLVDIXBGWPIS-UAKXSSHOSA-N
Solubility: Soluble in Water
SMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)I
IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
InChI: InChI=1S/C9H11IN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
Synonyms: NSC 523375; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 2,4-Dihydroxy-5-iodo-1-β-D-ribofuranosylpyrimidine; 5-Iodo-1-(β-D-ribofuranosyl)uracil; 5-Iodo Uridine
Adenosine (BRP-00021)

Adenosine

Description: Adenosine is a purine nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.
CAT: BRP-00021
CAS: 58-61-7
Molecular Formula: C10H13N5O4
Molecular Weight: 267.24
Purity: ≥95% by HPLC
Appearance: white crystalline powder
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Storage: Store at 2-8°C
Density: 2.08 g/cm3
Melting Point: 234-236°C
Boiling Point: 676.3°C at 760 mmHg
Application: neuromodulator
InChIKey: OIRDTQYFTABQOQ-KQYNXXCUSA-N
Solubility: Soluble in water
SMILES: C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CO)O)O
IUPAC Name: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChI: InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
Synonyms: Adenocard; Adenoscan; Adenine riboside; ribo Adenosine; rA; 9-β-D-Ribofuranosyl-9H-purin-6-amine; 9-β-D-Ribofuranosyladenine; D-Adenosine; Boniton; Myocol; NQZ-012; NSC 7652; Nucleocardyl; Riboadenosine; Sandesin; β-D-Adenosine; β-D-Ribofuranoside, adenine-9; β-Adenosine
Uridine (BRP-00038)

Uridine

Description: Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.
CAT: BRP-00038
CAS: 58-96-8
Molecular Formula: C9H12N2O6
Molecular Weight: 244.20
Purity: ≥98% by HPLC
Appearance: White crystalline powder
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Storage: Store at 2-8 °C
Density: 1.674±0.06 g/cm3
Melting Point: 165 °C
Boiling Point: 387.12°C (rough estimate)
InChIKey: DRTQHJPVMGBUCF-XVFCMESISA-N
Solubility: Soluble in Dimethylsulfoxide, Methanol, Water (50 mg/mL)
SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
Synonyms: Cytarabine Impurity B; 1-β-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione; 1-β-D-Ribofuranosyluracil; NSC 20256; Uracil riboside; 1-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione; Uridin; β-Uridine; Cytarabine EP Impurity B
N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine (BRP-00055)

N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine

Description: N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine, a remarkable biomedical compound renowned for its exceptional antiviral attributes, is indeed a profound breakthrough in the field. With its unrivaled inhibitory prowess against viral replication, this marvel exhibits immense promise in combatting treacherous RNA viruses, namely hepatitis C and dengue fever. Its captivating mode of operation revolves around perturbing viral RNA synthesis, thereby positioning itself as an invaluable contender within the realm of antiviral therapeutics.
CAT: BRP-00055
CAS: 440327-50-4
Molecular Formula: C17H25N5O7
Molecular Weight: 411.41
Purity: ≥95%
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20°C
Shelf Life: 2 years
InChIKey: IZOOGJIUOCHAAY-UBEDBUPSSA-N
SMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)OCCOC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C17H25N5O7/c1-8(2)14(25)20-17-19-13-10(15(26)21-17)18-7-22(13)16-12(28-5-4-27-3)11(24)9(6-23)29-16/h7-9,11-12,16,23-24H,4-6H2,1-3H3,(H2,19,20,21,25,26)/t9-,11-,12-,16-/m1/s1
Synonyms: N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; Guanosine, 2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-; 2'-O-MOE-N2-ibu-rG; N2-isobutyryl-2-O-(2-methoxyethyl)guanosine; N2-iBu-2'-O-MOE-G; N2-isobutyryl-2'-O-methoxyethyl-guanosine
4'-alpha-Azidouridine (BRP-00056)

4'-alpha-Azidouridine

Description: 4'-alpha-Azidouridine, a biomedical compound, assumes paramount significance in the realm of antiviral therapy. Its applications predominantly revolve around combating viral infections instigated by RNA viruses. By selectively and adeptly impeding viral replication and transcription, this compound emerges as an efficacious weapon against afflictions like influenza, hepatitis C, and HIV.
CAT: BRP-00056
CAS: 139442-01-6
Molecular Formula: C9H11N5O6
Molecular Weight: 285.21
Purity: ≥95%
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InChIKey: FHPJZSIIXUQGQE-JVZYCSMKSA-N
SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O
IUPAC Name: 1-[(2R,3R,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C9H11N5O6/c10-13-12-9(3-15)6(18)5(17)7(20-9)14-2-1-4(16)11-8(14)19/h1-2,5-7,15,17-18H,3H2,(H,11,16,19)/t5-,6+,7-,9-/m1/s1
Synonyms: 1-(4'-Azido-beta-D-ribofuranosyl)uracil; 4'-azidouridine; Uridine, 4-C-azido-; 1-[(2R,3R,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione; 4'-C-azidouridine
2'-C-methyladenosine (BRP-00057)

2'-C-methyladenosine

Description: 2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication (IC50 = 0.3 µM in Huh-7 human hepatoma cells) that is not cytotoxic at concentrations up to 100 µM.
CAT: BRP-00057
CAS: 15397-12-3
Molecular Formula: C11H15N5O4
Molecular Weight: 281.27
Purity: ≥95%
Appearance: Solid
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Storage: 4°C, protect from light
*In solvent
: -80°C, 6 months; -20°C, 1 month (protect from light)
Density: 1.89±0.1 g/cm3
Boiling Point: 643.4±65.0 °C at 760 mmHg
InChIKey: PASOFFRBGIVJET-YRKGHMEHSA-N
Solubility: Soluble in DMF, DMSO, PBS
SMILES: OC[C@@H]1[C@@H](O)[C@@](C)(O)[C@H](N2C3=NC=NC(N)=C3N=C2)O1
IUPAC Name: (2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol
InChI: InChI=1S/C11H15N5O4/c1-11(19)7(18)5(2-17)20-10(11)16-4-15-6-8(12)13-3-14-9(6)16/h3-5,7,10,17-19H,2H2,1H3,(H2,12,13,14)/t5-,7-,10-,11-/m1/s1
Synonyms: 2'-C-methyladenosine;15397-12-3;(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol;2'-methyl-adenosine;2-C-methyl adenosine;(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol;CHEMBL73809;2''-C-methyladenosine;2/'-C-Methyladenosine;(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-3,4-diol;2-c-methyladenosine;2''-methyl-adenosine;2'-C-Methyl-adenosine;2'-C-Methyl Adenosine;Beta-2'-Methyladenosine;beta-2''-Methyladenosine;2'-C-MeA;SCHEMBL382543;2'-C-Me-A;DTXSID90333334;PASOFFRBGIVJET-YRKGHMEHSA-N;2'-C-CH3-A;BCX-4026;BDBM50144948;MFCD02682944;AKOS015914550;BS-25234;DA-49398;PD077382;F12904;(3R)-2-(6-Aminopurin-9-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol;(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-3,4-diol;(2R,3R,4R,5R)-5-Hydroxymethyl-3-methyl-2-(6-methylamino-purin-9-yl)-tetrahydro-furan-3,4-diol;
2-C-methyl-6-O-methyl-guanosine (BRP-00058)

2-C-methyl-6-O-methyl-guanosine

Description: 2-C-methyl-6-O-methyl-guanosine - an exalted nucleoside analog flourishing in the realm of biomedical applications. As a prodigious antiviral agent, its dominion extends to combating the perils inflicted by RNA viruses like hepatitis C and respiratory syncytial virus (RSV). Proficiently curbing viral replication and subduing the viral life cycle, it has garnered reverence among scientific circles. Moreover, its boundless panorama of therapeutic possibilities in countering diverse viral afflictions continues to enthrall researchers worldwide. Beware, for this extraordinary entity is unrivaled in its prowess.
CAT: BRP-00058
CAS: 714249-80-6
Molecular Formula: C12H17N5O5
Molecular Weight: 311.29
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Density: 1.8±0.1 g/cm3
Boiling Point: 690.2±65.0 °C(Predicted)
InChIKey: OAIGYKVLSKBAJZ-GSWPYSDESA-N
SMILES: CC1(C(C(OC1N2C=NC3=C2N=C(N=C3OC)N)CO)O)O
IUPAC Name: (2R,3R,4R,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol
InChI: InChI=1S/C12H17N5O5/c1-12(20)7(19)5(3-18)22-10(12)17-4-14-6-8(17)15-11(13)16-9(6)21-2/h4-5,7,10,18-20H,3H2,1-2H3,(H2,13,15,16)/t5-,7-,10-,12-/m1/s1
Synonyms: (2R,3R,4R,5R)-2-(2-Amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol; 2'-C-Methyl-6-O-methyl-guanosine; INX 08144
2'-C-Methylcytidine (BRP-00059)

2'-C-Methylcytidine

Description: A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication.
CAT: BRP-00059
CAS: 20724-73-6
Molecular Formula: C10H15N3O5
Molecular Weight: 257.24
Purity: ≥95%
Appearance: white to off-white powder
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Storage: Store in a cool and dry place and at 2-8 °C for short term (days to weeks) or -20 °C for long term (months to years)
Density: 1.72±0.10 g/cm3
Melting Point: 243-245 °C
Boiling Point: 523.9±60.0 °C at 760 mmHg
Flash Point: 270.7±32.9 °C
Shelf Life: 2 years
InChIKey: PPUDLEUZKVJXSZ-VPCXQMTMSA-N
Solubility: Soluble in DMSO
SMILES: CC1(C(C(OC1N2C=CC(=NC2=O)N)CO)O)O
IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one
InChI: InChI=1S/C10H15N3O5/c1-10(17)7(15)5(4-14)18-8(10)13-3-2-6(11)12-9(13)16/h2-3,5,7-8,14-15,17H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,10-/m1/s1
Synonyms: 1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-4-aminopyrimidin-2(1H)-one; 2'-C-methyl-cytidine; valopicitabine; Cytidine, 2'-C-methyl-; (+)-2'-C-Methylcytidine; NM 107
Related CAS: 115494-60-5
2'-C-beta-Methylguanosine (BRP-00060)

2'-C-beta-Methylguanosine

Description: 2'-C-β-Methyl Guanosine is an anti-HCV agent. 2'-C-β-Methyl Guanosine is an intermediate in the synthesis of novel double prodrug INX-08189, a new clinical candidate for hepatitis C virus.
CAT: BRP-00060
CAS: 374750-30-8
Molecular Formula: C11H15N5O5
Molecular Weight: 297.27
Purity: ≥95%
Appearance: White to Beige Powder
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Storage: Store at -20°C
Density: 2.03 g/cm3
Boiling Point: 733.1±70.0°C (Predicted)
Application: A nucleoside derivative as antiviral, antitumor, and antidiabetic prodrug agents.
InChIKey: NVKAMPJSWMHVDK-GITKWUPZSA-N
Solubility: Soluble in Water
SMILES: CC1(C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O)O
IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1H-purin-6-one
InChI: InChI=1S/C11H15N5O5/c1-11(20)6(18)4(2-17)21-9(11)16-3-13-5-7(16)14-10(12)15-8(5)19/h3-4,6,9,17-18,20H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,9-,11-/m1/s1
Synonyms: 2'-C-Methylguanosine; 2'-C-β-Methyl Guanosine; 2-Amino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-(2-C-methyl-beta-D-ribofuranosyl)-; INX 08032; INZ 08032
2'-C-Methyluridine (BRP-00061)

2'-C-Methyluridine

Description: 2'-C-Methyluridine is a 2'-C-Me branched C-nucleoside that shows HCV polymerase inhibitory activity.
CAT: BRP-00061
CAS: 31448-54-1
Molecular Formula: C10H14N2O6
Molecular Weight: 258.23
Purity: ≥95%
Appearance: White to Off-white Powder
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Storage: Store at 2-8°C
Density: 1.57 g/cm3
Melting Point: 110-112 °C
InChIKey: NBKORJKMMVZAOZ-VPCXQMTMSA-N
SMILES: CC1(C(C(OC1N2C=CC(=O)NC2=O)CO)O)O
IUPAC Name: 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C10H14N2O6/c1-10(17)7(15)5(4-13)18-8(10)12-3-2-6(14)11-9(12)16/h2-3,5,7-8,13,15,17H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,10-/m1/s1
Synonyms: 2'-C-Methyl-1-β-D-ribofuranosyluracil; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Methyl Uridine; 1,3-bis(N-cyclohexyl)guanidine; 1-(2-C-Methyl-β-D-ribofuranosyl)uracil; 2,4(1H,3H)-pyrimidinedione, 1-(2-C-methyl-β-D-ribofuranosyl)-
N6-Cyclopentyl-adenosine (BRP-00062)

N6-Cyclopentyl-adenosine

Description: N6-Cyclopentyl-adenosine (CPA) - an adenosine analog and A1 adenosine receptor agonist - is pivotal in biomedicine as a research tool to inspect the part played by the adenosine receptor in distinct physiological processes. It also has potential therapeutic benefits that range from treating ischemia-reperfusion injuries to chronic pain.
CAT: BRP-00062
CAS: 41552-82-3
Molecular Formula: C15H21N5O4
Molecular Weight: 335.36
Purity: ≥95% by HPLC
Appearance: White to off-white solid
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Storage: Store at 2-8 °C
Density: 1.78±0.1 g/cm3 (Predicted)
Melting Point: 78.8 °C
Boiling Point: 673.4±65.0 °C at 760 mmHg
Application: Purinergic P1 Receptor Agonists
InChIKey: SQMWSBKSHWARHU-SDBHATRESA-N
Solubility: Soluble in Water
SMILES: C1CCC(C1)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O
IUPAC Name: (2R,3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
InChI: InChI=1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1
Synonyms: N6-Cyclopentyladenosine; CPA; N-Cyclopentyladenosine; UK 80882; (2R,3R,4S,5R)-2-[6-(Cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
3'-O-Methyluridine (BRP-00064)

3'-O-Methyluridine

Description: 3'-O-Methyluridine is a potent compound, serving as a therapeutic intervention for research of diverse viral infections and autoimmune conditions. Through its exceptional anti-replication properties, this remarkable compound effectively hampers viral proliferation.
CAT: BRP-00064
CAS: 6038-59-1
Molecular Formula: C10H14N2O6
Molecular Weight: 258.23
Purity: ≥95%
Appearance: White to Off-white Powder
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Storage: Store at -20°C
Density: 1.53±0.1 g/cm3
Melting Point: 142-145°C
InChIKey: YKNATSNMFLEFRB-ZOQUXTDFSA-N
SMILES: COC1C(OC(C1O)N2C=CC(=O)NC2=O)CO
IUPAC Name: 1-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C10H14N2O6/c1-17-8-5(4-13)18-9(7(8)15)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,9-/m1/s1
Synonyms: 3'-O-Methyl-D-uridine; O3'-methyl-uridine; 1-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 3'-O-Me-Ur; 3'-O-methyl-uridine; 3'-(O-Methyl) Uridine
3'-O-Methyladenosine (BRP-00065)

3'-O-Methyladenosine

Description: 3'-O-Methyladenosine, an indispensable biomolecule utilized in the realm of biomedical research, assumes a pivotal role in the meticulous exploration of RNA modifications. Ubiquitously present within a myriad of RNA molecules, this compound exerts profound influence on gene expression regulation, cellular signaling, and the genesis of diseases.
CAT: BRP-00065
CAS: 10300-22-8
Molecular Formula: C11H15N5O4
Molecular Weight: 281.27
Purity: ≥95%
Appearance: White Powder
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Storage: Store at -20°C
Density: 1.84±0.1 g/cm3(Predicted)
Melting Point: 177-178 °C
Boiling Point: 623.8±65.0 °C(Predicted)
InChIKey: RYAFZRROCNNRFK-IOSLPCCCSA-N
Solubility: Soluble in Methanol (10 mg/mL)
SMILES: COC1C(OC(C1O)N2C=NC3=C(N=CN=C32)N)CO
IUPAC Name: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-methoxyoxolan-3-ol
InChI: InChI=1S/C11H15N5O4/c1-19-8-5(2-17)20-11(7(8)18)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1
Synonyms: 3'-O-Methyl-D-adenosine; (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; NSC 103062; 3'-O-Methyl Adenosine; 3'-(O-Methyl) Adenosine
N6-Benzoyl-2'-O-methyladenosine (BRP-00067)

N6-Benzoyl-2'-O-methyladenosine

Description: N6-Benzoyl-2'-O-methyladenosine is an indispensable compound in the realm of biomedical research assuming a paramount role in the exploration of RNA modifications and epigenetics.
CAT: BRP-00067
CAS: 85079-00-1
Molecular Formula: C18H19N5O5
Molecular Weight: 385.37
Purity: ≥95%
Appearance: Off-white to Pale Yellow Powder
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Storage: Store at RT
Density: 1.59±0.1 g/cm3 (Predicted)
InChIKey: PHFHSPQCDRKMQJ-XWXWGSFUSA-N
SMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O
IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C18H19N5O5/c1-27-14-13(25)11(7-24)28-18(14)23-9-21-12-15(19-8-20-16(12)23)22-17(26)10-5-3-2-4-6-10/h2-6,8-9,11,13-14,18,24-25H,7H2,1H3,(H,19,20,22,26)/t11-,13-,14-,18-/m1/s1
Synonyms: N6-Benzoyl-2'-O-methyl-D-adenosine; Bz-2'-OMe-A; N-Benzoyl-2'-O-methyladenosine; N6-Benzoyl-2'-O-methyl-adenosine; 2'-O-methyl-N6-benzoyladenosine; N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; N6-Bz-2'-OMe-A; N6-Bz-2'-O-Me-Ar

Frequently Asked Questions (FAQ)

What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

* Only for research. Not suitable for any diagnostic or therapeutic use.

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