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Phosphoramidites

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2'-Modified Phosphoramidites
(594/594) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(246/246) 5'-Modified Phosphoramidites
(79/79) Arabino Phosphoramidites
(24/24) Base Protected Phosphoramidites (469/469) Dye Phosphoramidites
(72/72) Label Phosphoramidites
(86/86) Linker Phosphoramidites
(113/113) Other Phosphoramidites
(94/94) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(25/25) Spacer Phosphoramidites
(24/24)
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DMTr-2'-F-dU-3'-(D)-PSM-Phosphoramidite (BRP-02825)

DMTr-2'-F-dU-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-F-dU-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02825
Molecular Formula: C42H43FN3O10PS
Molecular Weight: 831.85
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: QARVJEVHPIHKEB-CHQVZEJJSA-N
SMILES: O=S(C[C@H]1[C@](CCC2)([H])N2[P@](O[C@H]3[C@@H](F)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O1)(C8=CC=CC=C8)=O
InChI: InChI=1S/C42H43FN3O10PS/c1-51-31-19-15-29(16-20-31)42(28-10-5-3-6-11-28,30-17-21-32(52-2)22-18-30)53-26-35-39(38(43)40(54-35)45-25-23-37(47)44-41(45)48)56-57-46-24-9-14-34(46)36(55-57)27-58(49,50)33-12-7-4-8-13-33/h3-8,10-13,15-23,25,34-36,38-40H,9,14,24,26-27H2,1-2H3,(H,44,47,48)/t34-,35-,36+,38-,39-,40-,57+/m1/s1
DMTr-2'-F-dA(Bz)-3'-(L)-PSM-Phosphoramidite (BRP-02826)

DMTr-2'-F-dA(Bz)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dA(Bz)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02826
Molecular Formula: C50H48FN6O9PS
Molecular Weight: 959.00
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: XNKVSLALPYQTFX-XTWIBHGUSA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C=NC5=C(NC(C6=CC=CC=C6)=O)N=CN=C54)O[C@@H]3COC(C7=CC=C(OC)C=C7)(C8=CC=C(OC)C=C8)C9=CC=CC=C9)O1)(C%10=CC=CC=C%10)=O
InChI: InChI=1S/C50H48FN6O9PS/c1-61-37-24-20-35(21-25-37)50(34-15-8-4-9-16-34,36-22-26-38(62-2)27-23-36)63-29-41-45(66-67-57-28-12-19-40(57)42(65-67)30-68(59,60)39-17-10-5-11-18-39)43(51)49(64-41)56-32-54-44-46(52-31-53-47(44)56)55-48(58)33-13-6-3-7-14-33/h3-11,13-18,20-27,31-32,40-43,45,49H,12,19,28-30H2,1-2H3,(H,52,53,55,58)/t40-,41+,42+,43+,45+,49+,67+/m0/s1
DMTr-2'-F-dG(iBu)-3'-(L)-PSM-Phosphoramidite (BRP-02827)

DMTr-2'-F-dG(iBu)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dG(iBu)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02827
Molecular Formula: C47H50FN6O10PS
Molecular Weight: 940.98
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: VGPMRAFQMYMCJH-FLAWJVCBSA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C=NC5=C4N=C(NC(C(C)C)=O)NC5=O)O[C@@H]3COC(C6=CC=C(OC)C=C6)(C7=CC=C(OC)C=C7)C8=CC=CC=C8)O1)(C9=CC=CC=C9)=O
InChI: InChI=1S/C47H50FN6O10PS/c1-29(2)43(55)51-46-50-42-40(44(56)52-46)49-28-53(42)45-39(48)41(64-65-54-25-11-16-36(54)38(63-65)27-66(57,58)35-14-9-6-10-15-35)37(62-45)26-61-47(30-12-7-5-8-13-30,31-17-21-33(59-3)22-18-31)32-19-23-34(60-4)24-20-32/h5-10,12-15,17-24,28-29,36-39,41,45H,11,16,25-27H2,1-4H3,(H2,50,51,52,55,56)/t36-,37+,38+,39+,41+,45+,65+/m0/s1
DMTr-2'-F-dC(Ac)-3'-(L)-PSM-Phosphoramidite (BRP-02828)

DMTr-2'-F-dC(Ac)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dC(Ac)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02828
Molecular Formula: C44H46FN4O10PS
Molecular Weight: 872.90
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: VMVJQKSBLJDIBX-DLAVVFPTSA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C(N=C(NC(C)=O)C=C4)=O)O[C@@H]3COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O1)(C8=CC=CC=C8)=O
InChI: InChI=1S/C44H46FN4O10PS/c1-29(50)46-39-24-26-48(43(51)47-39)42-40(45)41(59-60-49-25-10-15-36(49)38(58-60)28-61(52,53)35-13-8-5-9-14-35)37(57-42)27-56-44(30-11-6-4-7-12-30,31-16-20-33(54-2)21-17-31)32-18-22-34(55-3)23-19-32/h4-9,11-14,16-24,26,36-38,40-42H,10,15,25,27-28H2,1-3H3,(H,46,47,50,51)/t36-,37+,38+,40+,41+,42+,60+/m0/s1
DMTr-2'-F-dU-3'-(L)-PSM-Phosphoramidite (BRP-02829)

DMTr-2'-F-dU-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dU-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02829
Molecular Formula: C42H43FN3O10PS
Molecular Weight: 831.85
Purity: ≥98%
Size Price Stock Quantity
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Storage: Store at -20 °C
InChIKey: QARVJEVHPIHKEB-HCGCJGEBSA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O1)(C8=CC=CC=C8)=O
InChI: InChI=1S/C42H43FN3O10PS/c1-51-31-19-15-29(16-20-31)42(28-10-5-3-6-11-28,30-17-21-32(52-2)22-18-30)53-26-35-39(38(43)40(54-35)45-25-23-37(47)44-41(45)48)56-57-46-24-9-14-34(46)36(55-57)27-58(49,50)33-12-7-4-8-13-33/h3-8,10-13,15-23,25,34-36,38-40H,9,14,24,26-27H2,1-2H3,(H,44,47,48)/t34-,35+,36+,38+,39+,40+,57+/m0/s1
DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite (BRP-02830)

DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02830
Molecular Formula: C46H49FN7O9PS
Molecular Weight: 925.97
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: HIEYZPSJQFLOSQ-QSRQKFOGSA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C=NC5=C4N=C(/N=C/N(C)C)NC5=O)O[C@@H]3COC(C6=CC=C(OC)C=C6)(C7=CC=C(OC)C=C7)C8=CC=CC=C8)O1)(C9=CC=CC=C9)=O
InChI: InChI=1S/C46H49FN7O9PS/c1-52(2)28-49-45-50-42-40(43(55)51-45)48-29-53(42)44-39(47)41(63-64-54-25-11-16-36(54)38(62-64)27-65(56,57)35-14-9-6-10-15-35)37(61-44)26-60-46(30-12-7-5-8-13-30,31-17-21-33(58-3)22-18-31)32-19-23-34(59-4)24-20-32/h5-10,12-15,17-24,28-29,36-39,41,44H,11,16,25-27H2,1-4H3,(H,50,51,55)/b49-28+/t36-,37+,38+,39+,41+,44+,64+/m0/s1
5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite (BRP-02831)

5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite

Description: 5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02831
Molecular Formula: C35H49N3O15P2S
Molecular Weight: 845.79
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: MOOJEXMIUQVQCI-OKNXCLCVSA-N
SMILES: O=S(C[C@H]1[C@](CCC2)([H])N2[P@](O[C@H]3[C@@H](OC)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)O1)(C5=CC=CC=C5)=O
InChI: InChI=1S/C35H49N3O15P2S/c1-34(2,3)31(40)47-21-49-55(43,50-22-48-32(41)35(4,5)6)19-16-25-28(29(46-7)30(51-25)37-18-15-27(39)36-33(37)42)53-54-38-17-11-14-24(38)26(52-54)20-56(44,45)23-12-9-8-10-13-23/h8-10,12-13,15-16,18-19,24-26,28-30H,11,14,17,20-22H2,1-7H3,(H,36,39,42)/b19-16+/t24-,25-,26+,28-,29-,30-,54+/m1/s1
5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite (BRP-02832)

5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite

Description: 5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02832
Molecular Formula: C35H49N3O15P2S
Molecular Weight: 845.79
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: MOOJEXMIUQVQCI-JLWNIJTISA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](OC)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)O1)(C5=CC=CC=C5)=O
InChI: InChI=1S/C35H49N3O15P2S/c1-34(2,3)31(40)47-21-49-55(43,50-22-48-32(41)35(4,5)6)19-16-25-28(29(46-7)30(51-25)37-18-15-27(39)36-33(37)42)53-54-38-17-11-14-24(38)26(52-54)20-56(44,45)23-12-9-8-10-13-23/h8-10,12-13,15-16,18-19,24-26,28-30H,11,14,17,20-22H2,1-7H3,(H,36,39,42)/b19-16+/t24-,25+,26+,28+,29+,30+,54+/m0/s1
DMTr-2'-O-Me-rA(Bz)-3'-PS2-Amidite (BRP-02833)

DMTr-2'-O-Me-rA(Bz)-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rA(Bz)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02833
Molecular Formula: C52H53N6O8PS2
Molecular Weight: 985.12
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: CLDYJLPUISOESS-LTMMGAFGSA-N
SMILES: CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N8CCCC8)SCCSC(=O)C9=CC=CC=C9
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C52H53N6O8PS2/c1-61-41-25-21-39(22-26-41)52(38-19-11-6-12-20-38,40-23-27-42(62-2)28-24-40)64-33-43-45(66-67(57-29-13-14-30-57)69-32-31-68-51(60)37-17-9-5-10-18-37)46(63-3)50(65-43)58-35-55-44-47(53-34-54-48(44)58)56-49(59)36-15-7-4-8-16-36/h4-12,15-28,34-35,43,45-46,50H,13-14,29-33H2,1-3H3,(H,53,54,56,59)/t43-,45-,46-,50-,67?/m1/s1
Synonyms: DMTr-2'-O-Me-rA(Bz)-3'-Thiophosphoramidite
DMTr-2'-O-Me-rU-3'-PS2-Amidite (BRP-02834)

DMTr-2'-O-Me-rU-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rU-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02834
Molecular Formula: C44H48N3O9PS2
Molecular Weight: 857.97
Purity: ≥98%
Size Price Stock Quantity
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Storage: Store at -20 °C
InChIKey: WOJBALAHZBVIKR-QBLJBMGASA-N
SMILES: CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C44H48N3O9PS2/c1-51-35-20-16-33(17-21-35)44(32-14-8-5-9-15-32,34-18-22-36(52-2)23-19-34)54-30-37-39(40(53-3)41(55-37)47-27-24-38(48)45-43(47)50)56-57(46-25-10-11-26-46)59-29-28-58-42(49)31-12-6-4-7-13-31/h4-9,12-24,27,37,39-41H,10-11,25-26,28-30H2,1-3H3,(H,45,48,50)/t37-,39-,40-,41-,57?/m1/s1
Synonyms: DMTr-2'-O-Me-rU-3'-Thiophosphoramidite
DMTr-2'-O-Me-rG(iBu)-3'-PS2-Amidite (BRP-02835)

DMTr-2'-O-Me-rG(iBu)-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rG(iBu)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02835
Molecular Formula: C49H55N6O9PS2
Molecular Weight: 967.11
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: HZMNPGZRUUSWOU-VKFKYRIUSA-N
SMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N7CCCC7)SCCSC(=O)C8=CC=CC=C8)OC
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxy-5-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C49H55N6O9PS2/c1-32(2)44(56)52-48-51-43-40(45(57)53-48)50-31-55(43)46-42(61-5)41(64-65(54-26-12-13-27-54)67-29-28-66-47(58)33-14-8-6-9-15-33)39(63-46)30-62-49(34-16-10-7-11-17-34,35-18-22-37(59-3)23-19-35)36-20-24-38(60-4)25-21-36/h6-11,14-25,31-32,39,41-42,46H,12-13,26-30H2,1-5H3,(H2,51,52,53,56,57)/t39-,41-,42-,46-,65?/m1/s1
Synonyms: DMTr-2'-O-Me-rG(iBu)-3'-Thiophosphoramidite
DMTr-2'-O-Me-rC(Ac)-3'-PS2-Amidite (BRP-02836)

DMTr-2'-O-Me-rC(Ac)-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rC(Ac)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02836
Molecular Formula: C46H51N4O9PS2
Molecular Weight: 899.03
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: CNCXGATYHORASL-SRYSXPHVSA-N
SMILES: CC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7)OC
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C46H51N4O9PS2/c1-32(51)47-40-25-28-50(45(53)48-40)43-42(56-4)41(59-60(49-26-11-12-27-49)62-30-29-61-44(52)33-13-7-5-8-14-33)39(58-43)31-57-46(34-15-9-6-10-16-34,35-17-21-37(54-2)22-18-35)36-19-23-38(55-3)24-20-36/h5-10,13-25,28,39,41-43H,11-12,26-27,29-31H2,1-4H3,(H,47,48,51,53)/t39-,41-,42-,43-,60?/m1/s1
Synonyms: DMTr-2'-O-Me-rC(Ac)-3'-Thiophosphoramidite
DMTr-2'-F-dA(Bz)-3'-PS2-Amidite (BRP-02837)

DMTr-2'-F-dA(Bz)-3'-PS2-Amidite

Description: DMTr-2'-F-dA(Bz)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02837
Molecular Formula: C51H50FN6O7PS2
Molecular Weight: 973.09
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: PPULOMKIQMTGHV-PDBKPMKASA-N
SMILES: COC1=CC=C(C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N5CCCC5)SCCSC(C6=CC=CC=C6)=O)[C@@H](F)[C@H](N7C=NC8=C(NC(C9=CC=CC=C9)=O)N=CN=C87)O4)C=C1
InChI: InChI=1S/C51H50FN6O7PS2/c1-61-40-24-20-38(21-25-40)51(37-18-10-5-11-19-37,39-22-26-41(62-2)27-23-39)63-32-42-45(65-66(57-28-12-13-29-57)68-31-30-67-50(60)36-16-8-4-9-17-36)43(52)49(64-42)58-34-55-44-46(53-33-54-47(44)58)56-48(59)35-14-6-3-7-15-35/h3-11,14-27,33-34,42-43,45,49H,12-13,28-32H2,1-2H3,(H,53,54,56,59)/t42-,43-,45-,49-,66?/m1/s1
Synonyms: DMTr-2'-F-dA(Bz)-3'-Thiophosphoramidite
DMTr-2'-F-dG(iBu)-3'-PS2-Amidite (BRP-02838)

DMTr-2'-F-dG(iBu)-3'-PS2-Amidite

Description: DMTr-2'-F-dG(iBu)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02838
Molecular Formula: C48H52FN6O8PS2
Molecular Weight: 955.07
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: GOLSECBBKDTIRM-IMYAOLGDSA-N
SMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N7CCCC7)SCCSC(=O)C8=CC=CC=C8)F
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-fluoro-5-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C48H52FN6O8PS2/c1-31(2)43(56)52-47-51-42-40(44(57)53-47)50-30-55(42)45-39(49)41(63-64(54-25-11-12-26-54)66-28-27-65-46(58)32-13-7-5-8-14-32)38(62-45)29-61-48(33-15-9-6-10-16-33,34-17-21-36(59-3)22-18-34)35-19-23-37(60-4)24-20-35/h5-10,13-24,30-31,38-39,41,45H,11-12,25-29H2,1-4H3,(H2,51,52,53,56,57)/t38-,39-,41-,45-,64?/m1/s1
Synonyms: DMTr-2'-F-dG(iBu)-3'-Thiophosphoramidite
DMTr-2'-F-dC(Ac)-3'-PS2-Amidite (BRP-02839)

DMTr-2'-F-dC(Ac)-3'-PS2-Amidite

Description: DMTr-2'-F-dC(Ac)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02839
Molecular Formula: C45H48FN4O8PS2
Molecular Weight: 886.99
Purity: ≥98%
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InChIKey: YEUOGNRGLBQTSU-ZMHKPELYSA-N
SMILES: COC1=CC=C(C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N5CCCC5)SCCSC(C6=CC=CC=C6)=O)[C@@H](F)[C@H](N7C(N=C(NC(C)=O)C=C7)=O)O4)C=C1
InChI: InChI=1S/C45H48FN4O8PS2/c1-31(51)47-39-24-27-50(44(53)48-39)42-40(46)41(58-59(49-25-10-11-26-49)61-29-28-60-43(52)32-12-6-4-7-13-32)38(57-42)30-56-45(33-14-8-5-9-15-33,34-16-20-36(54-2)21-17-34)35-18-22-37(55-3)23-19-35/h4-9,12-24,27,38,40-42H,10-11,25-26,28-30H2,1-3H3,(H,47,48,51,53)/t38-,40-,41-,42-,59?/m1/s1
Synonyms: DMTr-2'-F-dC(Ac)-3'-Thiophosphoramidite
DMTr-2'-F-dU-3'-PS2-Amidite (BRP-02840)

DMTr-2'-F-dU-3'-PS2-Amidite

Description: DMTr-2'-F-dU-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02840
Molecular Formula: C43H45FN3O8PS2
Molecular Weight: 845.94
Purity: ≥98%
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InChIKey: HUXZGSPNSAYIPS-CYSIDSPMSA-N
SMILES: COC1=CC=C(C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N5CCCC5)SCCSC(C6=CC=CC=C6)=O)[C@@H](F)[C@H](N7C(NC(C=C7)=O)=O)O4)C=C1
InChI: InChI=1S/C43H45FN3O8PS2/c1-51-34-19-15-32(16-20-34)43(31-13-7-4-8-14-31,33-17-21-35(52-2)22-18-33)53-29-36-39(38(44)40(54-36)47-26-23-37(48)45-42(47)50)55-56(46-24-9-10-25-46)58-28-27-57-41(49)30-11-5-3-6-12-30/h3-8,11-23,26,36,38-40H,9-10,24-25,27-29H2,1-2H3,(H,45,48,50)/t36-,38-,39-,40-,56?/m1/s1
Synonyms: DMTr-2'-F-dU-3'-Thiophosphoramidite
DMTr-2'-O-C6-rA(Bz)-3'-CE-Phosphoramidite (BRP-02841)

DMTr-2'-O-C6-rA(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-C6-rA(Bz)-3'-CE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02841
CAS: 2642321-66-0
Molecular Formula: C53H64N7O8P
Molecular Weight: 958.09
Purity: ≥98%
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InChIKey: QGOPOAHCJYOCNH-RESYHYSISA-N
SMILES: CCCCCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-hexoxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C53H64N7O8P/c1-8-9-10-17-32-64-48-47(68-69(66-33-18-31-54)60(37(2)3)38(4)5)45(67-52(48)59-36-57-46-49(55-35-56-50(46)59)58-51(61)39-19-13-11-14-20-39)34-65-53(40-21-15-12-16-22-40,41-23-27-43(62-6)28-24-41)42-25-29-44(63-7)30-26-42/h11-16,19-30,35-38,45,47-48,52H,8-10,17-18,32-34H2,1-7H3,(H,55,56,58,61)/t45-,47-,48-,52-,69?/m1/s1
Synonyms: 2'-O-hexyl A(Bz) amidite
DMTr-2'-O-C6-rC(Bz)-3'-CE-Phosphoramidite (BRP-02842)

DMTr-2'-O-C6-rC(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-C6-rC(Bz)-3'-CE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02842
CAS: 2642321-61-5
Molecular Formula: C52H64N5O9P
Molecular Weight: 934.07
Purity: ≥98%
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InChIKey: RFWDWXMWINZAJF-NOJOPTKUSA-N
SMILES: CCCCCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-hexoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C52H64N5O9P/c1-8-9-10-17-34-62-48-47(66-67(64-35-18-32-53)57(37(2)3)38(4)5)45(65-50(48)56-33-31-46(55-51(56)59)54-49(58)39-19-13-11-14-20-39)36-63-52(40-21-15-12-16-22-40,41-23-27-43(60-6)28-24-41)42-25-29-44(61-7)30-26-42/h11-16,19-31,33,37-38,45,47-48,50H,8-10,17-18,34-36H2,1-7H3,(H,54,55,58,59)/t45-,47-,48-,50-,67?/m1/s1
Synonyms: 2'-O-hexyl C(Bz) amidite
DMTr-2'-O-C6-rG(iBu)-3'-CE-Phosphoramidite (BRP-02843)

DMTr-2'-O-C6-rG(iBu)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-C6-rG(iBu)-3'-CE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02843
CAS: 2642321-69-3
Molecular Formula: C50H66N7O9P
Molecular Weight: 940.07
Purity: ≥98%
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InChIKey: ZVDISOOZPNLAHG-IBSROIRUSA-N
SMILES: CCCCCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)NC(=O)C(C)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-hexoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C50H66N7O9P/c1-10-11-12-16-29-62-44-43(66-67(64-30-17-28-51)57(34(4)5)35(6)7)41(65-48(44)56-32-52-42-45(56)53-49(55-47(42)59)54-46(58)33(2)3)31-63-50(36-18-14-13-15-19-36,37-20-24-39(60-8)25-21-37)38-22-26-40(61-9)27-23-38/h13-15,18-27,32-35,41,43-44,48H,10-12,16-17,29-31H2,1-9H3,(H2,53,54,55,58,59)/t41-,43-,44-,48-,67?/m1/s1
Synonyms: 2'-O-hexyl G(iBu) amidite
6-FAM cyclohexyl Phosphoramidite (BRP-02844)

6-FAM cyclohexyl Phosphoramidite

Description: 6-FAM cyclohexyl Phosphoramidite is a fluorescent labeling reagent used in oligonucleotide synthesis. It contains a 6-carboxyfluorescein (6-FAM) fluorophore attached to a cyclohexyl phosphoramidite moiety, enabling the incorporation of a fluorescent label at the 5' end of DNA or RNA sequences during automated solid-phase synthesis. It is widely used in molecular biology applications including DNA sequencing, PCR fragment analysis, genotyping, and fluorescence resonance energy transfer (FRET) studies.
CAT: BRP-02844
CAS: 952290-59-4
Molecular Formula: C46H56N3O10P
Molecular Weight: 841.94
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InChIKey: XQQGPIGJGDFHGJ-NAKXWQLKSA-N
SMILES: N#CCCOP(N(C(C)C)C(C)C)O[C@@H](CC1)CCC1NC(C(C=C2C34C(C=C5)=C(OC6=C3C=CC(OC(C(C)(C)C)=O)=C6)C=C5OC(C(C)(C)C)=O)=CC=C2C(O4)=O)=O
InChI: InChI=1S/C46H56N3O10P/c1-27(2)49(28(3)4)60(54-23-11-22-47)59-31-15-13-30(14-16-31)48-40(50)29-12-19-34-37(24-29)46(58-41(34)51)35-20-17-32(55-42(52)44(5,6)7)25-38(35)57-39-26-33(18-21-36(39)46)56-43(53)45(8,9)10/h12,17-21,24-28,30-31H,11,13-16,23H2,1-10H3,(H,48,50)/t30?,31-,60?
Synonyms: 6-((4-(((2-Cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)cyclohexyl)carbamoyl)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate); 6-Fluorescein cyclohexyl phosphoramidite; FAM cyclohexyl phosphoramidite, 6-isomer; FAM phosphoramidite, 6-isomer (cyclohexyl); 6-Carboxyfluorescein phosphoramidite (cyclohexyl); 6-FAM Phosphoramidite ACH

Frequently Asked Questions (FAQ)

What are phosphoramidites used for?

Phosphoramidites are activated monomers used in solid-phase DNA and RNA oligonucleotide synthesis.

RNA phosphoramidites include additional 2′-hydroxyl protecting groups, making them more sensitive to moisture and handling conditions.

Moisture can cause premature hydrolysis of phosphoramidites, reducing coupling efficiency and synthesis yield.

Yes, high-quality phosphoramidites are essential for achieving good yields in long and complex oligonucleotide sequences.

Modified and specialty phosphoramidites are commonly used to introduce functional groups or labels into oligonucleotides.

* Only for research. Not suitable for any diagnostic or therapeutic use.

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