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Phosphoramidites

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2'-Modified Phosphoramidites
(594/594) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(246/246) 5'-Modified Phosphoramidites
(79/79) Arabino Phosphoramidites
(24/24) Base Protected Phosphoramidites (469/469) Dye Phosphoramidites
(63/63) Label Phosphoramidites
(81/81) Linker Phosphoramidites
(97/97) Other Phosphoramidites
(94/94) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(25/25) Spacer Phosphoramidites
(24/24)
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DMTr-2'-F-dU-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dU-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02818
CAS: 1528734-08-8
Molecular Formula: C49H51FN3O8PSi
Molecular Weight: 888.00
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: SWLDICAIEKIRDG-ULMIAZCZSA-N
CanonicalSMILES: F[C@H]1[C@H](N2C(NC(C=C2)=O)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@]6O[C@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@@]9([H])N6CCC9
InChI: InChI=1S/C49H51FN3O8PSi/c1-56-37-25-21-35(22-26-37)49(34-14-7-4-8-15-34,36-23-27-38(57-2)28-24-36)58-32-42-46(45(50)47(59-42)52-31-29-44(54)51-48(52)55)61-62-53-30-13-20-41(53)43(60-62)33-63(3,39-16-9-5-10-17-39)40-18-11-6-12-19-40/h4-12,14-19,21-29,31,41-43,45-47H,13,20,30,32-33H2,1-3H3,(H,51,54,55)/t41-,42+,43+,45+,46+,47+,62+/m0/s1

DMTr-2'-O-Me-rG(iBu)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rG(iBu)-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02819
Molecular Formula: C48H53N6O11PS
Molecular Weight: 953.02
Purity: ≥98%
Size Price Stock Quantity
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Storage: Store at -20 °C
InChIKey: QCPFOYJTUFIVGR-BKXFETEPSA-N
CanonicalSMILES: CC(C)C(NC(N1)=NC2=C(N=CN2[C@@H]3O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@@H](O[P@@]7O[C@@H](CS(=O)(C8=CC=CC=C8)=O)[C@]9([H])N7CCC9)[C@H]3OC)C1=O)=O
InChI: InChI=1S/C48H53N6O11PS/c1-30(2)44(55)51-47-50-43-40(45(56)52-47)49-29-53(43)46-42(61-5)41(65-66-54-26-12-17-37(54)39(64-66)28-67(57,58)36-15-10-7-11-16-36)38(63-46)27-62-48(31-13-8-6-9-14-31,32-18-22-34(59-3)23-19-32)33-20-24-35(60-4)25-21-33/h6-11,13-16,18-25,29-30,37-39,41-42,46H,12,17,26-28H2,1-5H3,(H2,50,51,52,55,56)/t37-,38-,39+,41-,42-,46-,66+/m1/s1

DMTr-2'-O-Me-rC(Ac)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rC(Ac)-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02820
Molecular Formula: C45H49N4O11PS
Molecular Weight: 884.94
Purity: ≥98%
Size Price Stock Quantity
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Storage: Store at -20 °C
InChIKey: AOAKYUMILRMJOU-LFPDPUHYSA-N
CanonicalSMILES: CC(NC(C=CN1[C@@H]2O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@@H](O[P@@]6O[C@@H](CS(=O)(C7=CC=CC=C7)=O)[C@]8([H])N6CCC8)[C@H]2OC)=NC1=O)=O
InChI: InChI=1S/C45H49N4O11PS/c1-30(50)46-40-25-27-48(44(51)47-40)43-42(56-4)41(60-61-49-26-11-16-37(49)39(59-61)29-62(52,53)36-14-9-6-10-15-36)38(58-43)28-57-45(31-12-7-5-8-13-31,32-17-21-34(54-2)22-18-32)33-19-23-35(55-3)24-20-33/h5-10,12-15,17-25,27,37-39,41-43H,11,16,26,28-29H2,1-4H3,(H,46,47,50,51)/t37-,38-,39+,41-,42-,43-,61+/m1/s1

DMTr-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02821
Molecular Formula: C43H46N3O11PS
Molecular Weight: 843.88
Purity: ≥98%
Size Price Stock Quantity
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Storage: Store at -20 °C
InChIKey: WALZCFCZIWHBMO-UDOAYZSSSA-N
CanonicalSMILES: O=C1NC(C=CN1[C@@H]2O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@@H](O[P@@]6O[C@@H](CS(=O)(C7=CC=CC=C7)=O)[C@]8([H])N6CCC8)[C@H]2OC)=O
InChI: InChI=1S/C43H46N3O11PS/c1-51-32-20-16-30(17-21-32)43(29-11-6-4-7-12-29,31-18-22-33(52-2)23-19-31)54-27-36-39(40(53-3)41(55-36)45-26-24-38(47)44-42(45)48)57-58-46-25-10-15-35(46)37(56-58)28-59(49,50)34-13-8-5-9-14-34/h4-9,11-14,16-24,26,35-37,39-41H,10,15,25,27-28H2,1-3H3,(H,44,47,48)/t35-,36-,37+,39-,40-,41-,58+/m1/s1

DMTr-2'-F-dA(Bz)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-F-dA(Bz)-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02822
Molecular Formula: C50H48FN6O9PS
Molecular Weight: 959.00
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: XNKVSLALPYQTFX-PYSJVOCBSA-N
CanonicalSMILES: O=S(C[C@H]1[C@](CCC2)([H])N2[P@](O[C@H]3[C@@H](F)[C@H](N4C=NC5=C(NC(C6=CC=CC=C6)=O)N=CN=C54)O[C@@H]3COC(C7=CC=C(OC)C=C7)(C8=CC=C(OC)C=C8)C9=CC=CC=C9)O1)(C%10=CC=CC=C%10)=O
InChI: InChI=1S/C50H48FN6O9PS/c1-61-37-24-20-35(21-25-37)50(34-15-8-4-9-16-34,36-22-26-38(62-2)27-23-36)63-29-41-45(66-67-57-28-12-19-40(57)42(65-67)30-68(59,60)39-17-10-5-11-18-39)43(51)49(64-41)56-32-54-44-46(52-31-53-47(44)56)55-48(58)33-13-6-3-7-14-33/h3-11,13-18,20-27,31-32,40-43,45,49H,12,19,28-30H2,1-2H3,(H,52,53,55,58)/t40-,41-,42+,43-,45-,49-,67+/m1/s1

DMTr-2'-F-dG(iBu)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-F-dG(iBu)-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02823
Molecular Formula: C47H50FN6O10PS
Molecular Weight: 940.98
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: VGPMRAFQMYMCJH-IXGNQCOLSA-N
CanonicalSMILES: CC(C)C(NC(N1)=NC2=C(N=CN2[C@@H]3O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@@H](O[P@@]7O[C@@H](CS(=O)(C8=CC=CC=C8)=O)[C@]9([H])N7CCC9)[C@H]3F)C1=O)=O
InChI: InChI=1S/C47H50FN6O10PS/c1-29(2)43(55)51-46-50-42-40(44(56)52-46)49-28-53(42)45-39(48)41(64-65-54-25-11-16-36(54)38(63-65)27-66(57,58)35-14-9-6-10-15-35)37(62-45)26-61-47(30-12-7-5-8-13-30,31-17-21-33(59-3)22-18-31)32-19-23-34(60-4)24-20-32/h5-10,12-15,17-24,28-29,36-39,41,45H,11,16,25-27H2,1-4H3,(H2,50,51,52,55,56)/t36-,37-,38+,39-,41-,45-,65+/m1/s1

DMTr-2'-F-dC(Ac)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-F-dC(Ac)-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02824
Molecular Formula: C44H46FN4O10PS
Molecular Weight: 872.90
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: VMVJQKSBLJDIBX-ROFPKKATSA-N
CanonicalSMILES: O=S(C[C@H]1[C@](CCC2)([H])N2[P@](O[C@H]3[C@@H](F)[C@H](N4C(N=C(NC(C)=O)C=C4)=O)O[C@@H]3COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O1)(C8=CC=CC=C8)=O
InChI: InChI=1S/C44H46FN4O10PS/c1-29(50)46-39-24-26-48(43(51)47-39)42-40(45)41(59-60-49-25-10-15-36(49)38(58-60)28-61(52,53)35-13-8-5-9-14-35)37(57-42)27-56-44(30-11-6-4-7-12-30,31-16-20-33(54-2)21-17-31)32-18-22-34(55-3)23-19-32/h4-9,11-14,16-24,26,36-38,40-42H,10,15,25,27-28H2,1-3H3,(H,46,47,50,51)/t36-,37-,38+,40-,41-,42-,60+/m1/s1

DMTr-2'-F-dU-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-F-dU-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02825
Molecular Formula: C42H43FN3O10PS
Molecular Weight: 831.85
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: QARVJEVHPIHKEB-CHQVZEJJSA-N
CanonicalSMILES: O=S(C[C@H]1[C@](CCC2)([H])N2[P@](O[C@H]3[C@@H](F)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O1)(C8=CC=CC=C8)=O
InChI: InChI=1S/C42H43FN3O10PS/c1-51-31-19-15-29(16-20-31)42(28-10-5-3-6-11-28,30-17-21-32(52-2)22-18-30)53-26-35-39(38(43)40(54-35)45-25-23-37(47)44-41(45)48)56-57-46-24-9-14-34(46)36(55-57)27-58(49,50)33-12-7-4-8-13-33/h3-8,10-13,15-23,25,34-36,38-40H,9,14,24,26-27H2,1-2H3,(H,44,47,48)/t34-,35-,36+,38-,39-,40-,57+/m1/s1

DMTr-2'-F-dA(Bz)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dA(Bz)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02826
Molecular Formula: C50H48FN6O9PS
Molecular Weight: 959.00
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: XNKVSLALPYQTFX-XTWIBHGUSA-N
CanonicalSMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C=NC5=C(NC(C6=CC=CC=C6)=O)N=CN=C54)O[C@@H]3COC(C7=CC=C(OC)C=C7)(C8=CC=C(OC)C=C8)C9=CC=CC=C9)O1)(C%10=CC=CC=C%10)=O
InChI: InChI=1S/C50H48FN6O9PS/c1-61-37-24-20-35(21-25-37)50(34-15-8-4-9-16-34,36-22-26-38(62-2)27-23-36)63-29-41-45(66-67-57-28-12-19-40(57)42(65-67)30-68(59,60)39-17-10-5-11-18-39)43(51)49(64-41)56-32-54-44-46(52-31-53-47(44)56)55-48(58)33-13-6-3-7-14-33/h3-11,13-18,20-27,31-32,40-43,45,49H,12,19,28-30H2,1-2H3,(H,52,53,55,58)/t40-,41+,42+,43+,45+,49+,67+/m0/s1

DMTr-2'-F-dG(iBu)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dG(iBu)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02827
Molecular Formula: C47H50FN6O10PS
Molecular Weight: 940.98
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: VGPMRAFQMYMCJH-FLAWJVCBSA-N
CanonicalSMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C=NC5=C4N=C(NC(C(C)C)=O)NC5=O)O[C@@H]3COC(C6=CC=C(OC)C=C6)(C7=CC=C(OC)C=C7)C8=CC=CC=C8)O1)(C9=CC=CC=C9)=O
InChI: InChI=1S/C47H50FN6O10PS/c1-29(2)43(55)51-46-50-42-40(44(56)52-46)49-28-53(42)45-39(48)41(64-65-54-25-11-16-36(54)38(63-65)27-66(57,58)35-14-9-6-10-15-35)37(62-45)26-61-47(30-12-7-5-8-13-30,31-17-21-33(59-3)22-18-31)32-19-23-34(60-4)24-20-32/h5-10,12-15,17-24,28-29,36-39,41,45H,11,16,25-27H2,1-4H3,(H2,50,51,52,55,56)/t36-,37+,38+,39+,41+,45+,65+/m0/s1

DMTr-2'-F-dC(Ac)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dC(Ac)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02828
Molecular Formula: C44H46FN4O10PS
Molecular Weight: 872.90
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: VMVJQKSBLJDIBX-DLAVVFPTSA-N
CanonicalSMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C(N=C(NC(C)=O)C=C4)=O)O[C@@H]3COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O1)(C8=CC=CC=C8)=O
InChI: InChI=1S/C44H46FN4O10PS/c1-29(50)46-39-24-26-48(43(51)47-39)42-40(45)41(59-60-49-25-10-15-36(49)38(58-60)28-61(52,53)35-13-8-5-9-14-35)37(57-42)27-56-44(30-11-6-4-7-12-30,31-16-20-33(54-2)21-17-31)32-18-22-34(55-3)23-19-32/h4-9,11-14,16-24,26,36-38,40-42H,10,15,25,27-28H2,1-3H3,(H,46,47,50,51)/t36-,37+,38+,40+,41+,42+,60+/m0/s1

DMTr-2'-F-dU-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dU-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02829
Molecular Formula: C42H43FN3O10PS
Molecular Weight: 831.85
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: QARVJEVHPIHKEB-HCGCJGEBSA-N
CanonicalSMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O1)(C8=CC=CC=C8)=O
InChI: InChI=1S/C42H43FN3O10PS/c1-51-31-19-15-29(16-20-31)42(28-10-5-3-6-11-28,30-17-21-32(52-2)22-18-30)53-26-35-39(38(43)40(54-35)45-25-23-37(47)44-41(45)48)56-57-46-24-9-14-34(46)36(55-57)27-58(49,50)33-12-7-4-8-13-33/h3-8,10-13,15-23,25,34-36,38-40H,9,14,24,26-27H2,1-2H3,(H,44,47,48)/t34-,35+,36+,38+,39+,40+,57+/m0/s1

DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02830
Molecular Formula: C46H49FN7O9PS
Molecular Weight: 925.97
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: HIEYZPSJQFLOSQ-QSRQKFOGSA-N
CanonicalSMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C=NC5=C4N=C(/N=C/N(C)C)NC5=O)O[C@@H]3COC(C6=CC=C(OC)C=C6)(C7=CC=C(OC)C=C7)C8=CC=CC=C8)O1)(C9=CC=CC=C9)=O
InChI: InChI=1S/C46H49FN7O9PS/c1-52(2)28-49-45-50-42-40(43(55)51-45)48-29-53(42)44-39(47)41(63-64-54-25-11-16-36(54)38(62-64)27-65(56,57)35-14-9-6-10-15-35)37(61-44)26-60-46(30-12-7-5-8-13-30,31-17-21-33(58-3)22-18-31)32-19-23-34(59-4)24-20-32/h5-10,12-15,17-24,28-29,36-39,41,44H,11,16,25-27H2,1-4H3,(H,50,51,55)/b49-28+/t36-,37+,38+,39+,41+,44+,64+/m0/s1

5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite

Description: 5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02831
Molecular Formula: C35H49N3O15P2S
Molecular Weight: 845.79
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: MOOJEXMIUQVQCI-OKNXCLCVSA-N
CanonicalSMILES: O=S(C[C@H]1[C@](CCC2)([H])N2[P@](O[C@H]3[C@@H](OC)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)O1)(C5=CC=CC=C5)=O
InChI: InChI=1S/C35H49N3O15P2S/c1-34(2,3)31(40)47-21-49-55(43,50-22-48-32(41)35(4,5)6)19-16-25-28(29(46-7)30(51-25)37-18-15-27(39)36-33(37)42)53-54-38-17-11-14-24(38)26(52-54)20-56(44,45)23-12-9-8-10-13-23/h8-10,12-13,15-16,18-19,24-26,28-30H,11,14,17,20-22H2,1-7H3,(H,36,39,42)/b19-16+/t24-,25-,26+,28-,29-,30-,54+/m1/s1

5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite

Description: 5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02832
Molecular Formula: C35H49N3O15P2S
Molecular Weight: 845.79
Purity: ≥98%
Size Price Stock Quantity
-- -- --
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Storage: Store at -20 °C
InChIKey: MOOJEXMIUQVQCI-JLWNIJTISA-N
CanonicalSMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](OC)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)O1)(C5=CC=CC=C5)=O
InChI: InChI=1S/C35H49N3O15P2S/c1-34(2,3)31(40)47-21-49-55(43,50-22-48-32(41)35(4,5)6)19-16-25-28(29(46-7)30(51-25)37-18-15-27(39)36-33(37)42)53-54-38-17-11-14-24(38)26(52-54)20-56(44,45)23-12-9-8-10-13-23/h8-10,12-13,15-16,18-19,24-26,28-30H,11,14,17,20-22H2,1-7H3,(H,36,39,42)/b19-16+/t24-,25+,26+,28+,29+,30+,54+/m0/s1

DMTr-2'-O-Me-rA(Bz)-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rA(Bz)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02833
Molecular Formula: C52H53N6O8PS2
Molecular Weight: 985.12
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: CLDYJLPUISOESS-LTMMGAFGSA-N
CanonicalSMILES: CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N8CCCC8)SCCSC(=O)C9=CC=CC=C9
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C52H53N6O8PS2/c1-61-41-25-21-39(22-26-41)52(38-19-11-6-12-20-38,40-23-27-42(62-2)28-24-40)64-33-43-45(66-67(57-29-13-14-30-57)69-32-31-68-51(60)37-17-9-5-10-18-37)46(63-3)50(65-43)58-35-55-44-47(53-34-54-48(44)58)56-49(59)36-15-7-4-8-16-36/h4-12,15-28,34-35,43,45-46,50H,13-14,29-33H2,1-3H3,(H,53,54,56,59)/t43-,45-,46-,50-,67?/m1/s1
Synonyms: DMTr-2'-O-Me-rA(Bz)-3'-Thiophosphoramidite

DMTr-2'-O-Me-rU-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rU-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02834
Molecular Formula: C44H48N3O9PS2
Molecular Weight: 857.97
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: WOJBALAHZBVIKR-QBLJBMGASA-N
CanonicalSMILES: CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C44H48N3O9PS2/c1-51-35-20-16-33(17-21-35)44(32-14-8-5-9-15-32,34-18-22-36(52-2)23-19-34)54-30-37-39(40(53-3)41(55-37)47-27-24-38(48)45-43(47)50)56-57(46-25-10-11-26-46)59-29-28-58-42(49)31-12-6-4-7-13-31/h4-9,12-24,27,37,39-41H,10-11,25-26,28-30H2,1-3H3,(H,45,48,50)/t37-,39-,40-,41-,57?/m1/s1
Synonyms: DMTr-2'-O-Me-rU-3'-Thiophosphoramidite

DMTr-2'-O-Me-rG(iBu)-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rG(iBu)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02835
Molecular Formula: C49H55N6O9PS2
Molecular Weight: 967.11
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: HZMNPGZRUUSWOU-VKFKYRIUSA-N
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N7CCCC7)SCCSC(=O)C8=CC=CC=C8)OC
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxy-5-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C49H55N6O9PS2/c1-32(2)44(56)52-48-51-43-40(45(57)53-48)50-31-55(43)46-42(61-5)41(64-65(54-26-12-13-27-54)67-29-28-66-47(58)33-14-8-6-9-15-33)39(63-46)30-62-49(34-16-10-7-11-17-34,35-18-22-37(59-3)23-19-35)36-20-24-38(60-4)25-21-36/h6-11,14-25,31-32,39,41-42,46H,12-13,26-30H2,1-5H3,(H2,51,52,53,56,57)/t39-,41-,42-,46-,65?/m1/s1
Synonyms: DMTr-2'-O-Me-rG(iBu)-3'-Thiophosphoramidite

DMTr-2'-O-Me-rC(Ac)-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rC(Ac)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02836
Molecular Formula: C46H51N4O9PS2
Molecular Weight: 899.03
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: CNCXGATYHORASL-SRYSXPHVSA-N
CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7)OC
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C46H51N4O9PS2/c1-32(51)47-40-25-28-50(45(53)48-40)43-42(56-4)41(59-60(49-26-11-12-27-49)62-30-29-61-44(52)33-13-7-5-8-14-33)39(58-43)31-57-46(34-15-9-6-10-16-34,35-17-21-37(54-2)22-18-35)36-19-23-38(55-3)24-20-36/h5-10,13-25,28,39,41-43H,11-12,26-27,29-31H2,1-4H3,(H,47,48,51,53)/t39-,41-,42-,43-,60?/m1/s1
Synonyms: DMTr-2'-O-Me-rC(Ac)-3'-Thiophosphoramidite

DMTr-2'-F-dA(Bz)-3'-PS2-Amidite

Description: DMTr-2'-F-dA(Bz)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02837
Molecular Formula: C51H50FN6O7PS2
Molecular Weight: 973.09
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: PPULOMKIQMTGHV-PDBKPMKASA-N
CanonicalSMILES: COC1=CC=C(C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N5CCCC5)SCCSC(C6=CC=CC=C6)=O)[C@@H](F)[C@H](N7C=NC8=C(NC(C9=CC=CC=C9)=O)N=CN=C87)O4)C=C1
InChI: InChI=1S/C51H50FN6O7PS2/c1-61-40-24-20-38(21-25-40)51(37-18-10-5-11-19-37,39-22-26-41(62-2)27-23-39)63-32-42-45(65-66(57-28-12-13-29-57)68-31-30-67-50(60)36-16-8-4-9-17-36)43(52)49(64-42)58-34-55-44-46(53-33-54-47(44)58)56-48(59)35-14-6-3-7-15-35/h3-11,14-27,33-34,42-43,45,49H,12-13,28-32H2,1-2H3,(H,53,54,56,59)/t42-,43-,45-,49-,66?/m1/s1
Synonyms: DMTr-2'-F-dA(Bz)-3'-Thiophosphoramidite

Frequently Asked Questions (FAQ)

What are phosphoramidites used for?

Phosphoramidites are activated monomers used in solid-phase DNA and RNA oligonucleotide synthesis.

What is the difference between DNA and RNA phosphoramidites?

RNA phosphoramidites include additional 2′-hydroxyl protecting groups, making them more sensitive to moisture and handling conditions.

Why is moisture control important for phosphoramidites?

Moisture can cause premature hydrolysis of phosphoramidites, reducing coupling efficiency and synthesis yield.

Can phosphoramidites be used for long oligonucleotide synthesis?

Yes, high-quality phosphoramidites are essential for achieving good yields in long and complex oligonucleotide sequences.

Are modified phosphoramidites available for custom oligos?

Modified and specialty phosphoramidites are commonly used to introduce functional groups or labels into oligonucleotides.

* Only for research. Not suitable for any diagnostic or therapeutic use.

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