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Phosphoramidites

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2'-Modified Phosphoramidites
(594/594) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(246/246) 5'-Modified Phosphoramidites
(79/79) Arabino Phosphoramidites
(24/24) Base Protected Phosphoramidites (469/469) Dye Phosphoramidites
(72/72) Label Phosphoramidites
(86/86) Linker Phosphoramidites
(113/113) Other Phosphoramidites
(94/94) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(25/25) Spacer Phosphoramidites
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DMTr-2'-F-dU-3'-(D)-PSM-Phosphoramidite (BRP-02825) chemical structure

DMTr-2'-F-dU-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-F-dU-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02825
Molecular Formula: C42H43FN3O10PS
Molecular Weight: 831.85
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: QARVJEVHPIHKEB-CHQVZEJJSA-N
SMILES: O=S(C[C@H]1[C@](CCC2)([H])N2[P@](O[C@H]3[C@@H](F)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O1)(C8=CC=CC=C8)=O
InChI: InChI=1S/C42H43FN3O10PS/c1-51-31-19-15-29(16-20-31)42(28-10-5-3-6-11-28,30-17-21-32(52-2)22-18-30)53-26-35-39(38(43)40(54-35)45-25-23-37(47)44-41(45)48)56-57-46-24-9-14-34(46)36(55-57)27-58(49,50)33-12-7-4-8-13-33/h3-8,10-13,15-23,25,34-36,38-40H,9,14,24,26-27H2,1-2H3,(H,44,47,48)/t34-,35-,36+,38-,39-,40-,57+/m1/s1
DMTr-2'-F-dA(Bz)-3'-(L)-PSM-Phosphoramidite (BRP-02826) chemical structure

DMTr-2'-F-dA(Bz)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dA(Bz)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02826
Molecular Formula: C50H48FN6O9PS
Molecular Weight: 959.00
Purity: ≥98%
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InChIKey: XNKVSLALPYQTFX-XTWIBHGUSA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C=NC5=C(NC(C6=CC=CC=C6)=O)N=CN=C54)O[C@@H]3COC(C7=CC=C(OC)C=C7)(C8=CC=C(OC)C=C8)C9=CC=CC=C9)O1)(C%10=CC=CC=C%10)=O
InChI: InChI=1S/C50H48FN6O9PS/c1-61-37-24-20-35(21-25-37)50(34-15-8-4-9-16-34,36-22-26-38(62-2)27-23-36)63-29-41-45(66-67-57-28-12-19-40(57)42(65-67)30-68(59,60)39-17-10-5-11-18-39)43(51)49(64-41)56-32-54-44-46(52-31-53-47(44)56)55-48(58)33-13-6-3-7-14-33/h3-11,13-18,20-27,31-32,40-43,45,49H,12,19,28-30H2,1-2H3,(H,52,53,55,58)/t40-,41+,42+,43+,45+,49+,67+/m0/s1
DMTr-2'-F-dG(iBu)-3'-(L)-PSM-Phosphoramidite (BRP-02827) chemical structure

DMTr-2'-F-dG(iBu)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dG(iBu)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02827
Molecular Formula: C47H50FN6O10PS
Molecular Weight: 940.98
Purity: ≥98%
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InChIKey: VGPMRAFQMYMCJH-FLAWJVCBSA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C=NC5=C4N=C(NC(C(C)C)=O)NC5=O)O[C@@H]3COC(C6=CC=C(OC)C=C6)(C7=CC=C(OC)C=C7)C8=CC=CC=C8)O1)(C9=CC=CC=C9)=O
InChI: InChI=1S/C47H50FN6O10PS/c1-29(2)43(55)51-46-50-42-40(44(56)52-46)49-28-53(42)45-39(48)41(64-65-54-25-11-16-36(54)38(63-65)27-66(57,58)35-14-9-6-10-15-35)37(62-45)26-61-47(30-12-7-5-8-13-30,31-17-21-33(59-3)22-18-31)32-19-23-34(60-4)24-20-32/h5-10,12-15,17-24,28-29,36-39,41,45H,11,16,25-27H2,1-4H3,(H2,50,51,52,55,56)/t36-,37+,38+,39+,41+,45+,65+/m0/s1
DMTr-2'-F-dC(Ac)-3'-(L)-PSM-Phosphoramidite (BRP-02828) chemical structure

DMTr-2'-F-dC(Ac)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dC(Ac)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02828
Molecular Formula: C44H46FN4O10PS
Molecular Weight: 872.90
Purity: ≥98%
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InChIKey: VMVJQKSBLJDIBX-DLAVVFPTSA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C(N=C(NC(C)=O)C=C4)=O)O[C@@H]3COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O1)(C8=CC=CC=C8)=O
InChI: InChI=1S/C44H46FN4O10PS/c1-29(50)46-39-24-26-48(43(51)47-39)42-40(45)41(59-60-49-25-10-15-36(49)38(58-60)28-61(52,53)35-13-8-5-9-14-35)37(57-42)27-56-44(30-11-6-4-7-12-30,31-16-20-33(54-2)21-17-31)32-18-22-34(55-3)23-19-32/h4-9,11-14,16-24,26,36-38,40-42H,10,15,25,27-28H2,1-3H3,(H,46,47,50,51)/t36-,37+,38+,40+,41+,42+,60+/m0/s1
DMTr-2'-F-dU-3'-(L)-PSM-Phosphoramidite (BRP-02829) chemical structure

DMTr-2'-F-dU-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dU-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02829
Molecular Formula: C42H43FN3O10PS
Molecular Weight: 831.85
Purity: ≥98%
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InChIKey: QARVJEVHPIHKEB-HCGCJGEBSA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O1)(C8=CC=CC=C8)=O
InChI: InChI=1S/C42H43FN3O10PS/c1-51-31-19-15-29(16-20-31)42(28-10-5-3-6-11-28,30-17-21-32(52-2)22-18-30)53-26-35-39(38(43)40(54-35)45-25-23-37(47)44-41(45)48)56-57-46-24-9-14-34(46)36(55-57)27-58(49,50)33-12-7-4-8-13-33/h3-8,10-13,15-23,25,34-36,38-40H,9,14,24,26-27H2,1-2H3,(H,44,47,48)/t34-,35+,36+,38+,39+,40+,57+/m0/s1
DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite (BRP-02830) chemical structure

DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02830
Molecular Formula: C46H49FN7O9PS
Molecular Weight: 925.97
Purity: ≥98%
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InChIKey: HIEYZPSJQFLOSQ-QSRQKFOGSA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](F)[C@H](N4C=NC5=C4N=C(/N=C/N(C)C)NC5=O)O[C@@H]3COC(C6=CC=C(OC)C=C6)(C7=CC=C(OC)C=C7)C8=CC=CC=C8)O1)(C9=CC=CC=C9)=O
InChI: InChI=1S/C46H49FN7O9PS/c1-52(2)28-49-45-50-42-40(43(55)51-45)48-29-53(42)44-39(47)41(63-64-54-25-11-16-36(54)38(62-64)27-65(56,57)35-14-9-6-10-15-35)37(61-44)26-60-46(30-12-7-5-8-13-30,31-17-21-33(58-3)22-18-31)32-19-23-34(59-4)24-20-32/h5-10,12-15,17-24,28-29,36-39,41,44H,11,16,25-27H2,1-4H3,(H,50,51,55)/b49-28+/t36-,37+,38+,39+,41+,44+,64+/m0/s1
5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite (BRP-02831) chemical structure

5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite

Description: 5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02831
Molecular Formula: C35H49N3O15P2S
Molecular Weight: 845.79
Purity: ≥98%
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InChIKey: MOOJEXMIUQVQCI-OKNXCLCVSA-N
SMILES: O=S(C[C@H]1[C@](CCC2)([H])N2[P@](O[C@H]3[C@@H](OC)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)O1)(C5=CC=CC=C5)=O
InChI: InChI=1S/C35H49N3O15P2S/c1-34(2,3)31(40)47-21-49-55(43,50-22-48-32(41)35(4,5)6)19-16-25-28(29(46-7)30(51-25)37-18-15-27(39)36-33(37)42)53-54-38-17-11-14-24(38)26(52-54)20-56(44,45)23-12-9-8-10-13-23/h8-10,12-13,15-16,18-19,24-26,28-30H,11,14,17,20-22H2,1-7H3,(H,36,39,42)/b19-16+/t24-,25-,26+,28-,29-,30-,54+/m1/s1
5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite (BRP-02832) chemical structure

5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite

Description: 5'-POM-(E)-Vinyl Phosphonate-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02832
Molecular Formula: C35H49N3O15P2S
Molecular Weight: 845.79
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: MOOJEXMIUQVQCI-JLWNIJTISA-N
SMILES: O=S(C[C@@H]1[C@@](CCC2)([H])N2[P@@](O[C@H]3[C@@H](OC)[C@H](N4C(NC(C=C4)=O)=O)O[C@@H]3/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)O1)(C5=CC=CC=C5)=O
InChI: InChI=1S/C35H49N3O15P2S/c1-34(2,3)31(40)47-21-49-55(43,50-22-48-32(41)35(4,5)6)19-16-25-28(29(46-7)30(51-25)37-18-15-27(39)36-33(37)42)53-54-38-17-11-14-24(38)26(52-54)20-56(44,45)23-12-9-8-10-13-23/h8-10,12-13,15-16,18-19,24-26,28-30H,11,14,17,20-22H2,1-7H3,(H,36,39,42)/b19-16+/t24-,25+,26+,28+,29+,30+,54+/m0/s1
DMTr-2'-O-Me-rA(Bz)-3'-PS2-Amidite (BRP-02833) chemical structure

DMTr-2'-O-Me-rA(Bz)-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rA(Bz)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02833
Molecular Formula: C52H53N6O8PS2
Molecular Weight: 985.12
Purity: ≥98%
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InChIKey: CLDYJLPUISOESS-LTMMGAFGSA-N
SMILES: CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N8CCCC8)SCCSC(=O)C9=CC=CC=C9
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C52H53N6O8PS2/c1-61-41-25-21-39(22-26-41)52(38-19-11-6-12-20-38,40-23-27-42(62-2)28-24-40)64-33-43-45(66-67(57-29-13-14-30-57)69-32-31-68-51(60)37-17-9-5-10-18-37)46(63-3)50(65-43)58-35-55-44-47(53-34-54-48(44)58)56-49(59)36-15-7-4-8-16-36/h4-12,15-28,34-35,43,45-46,50H,13-14,29-33H2,1-3H3,(H,53,54,56,59)/t43-,45-,46-,50-,67?/m1/s1
Synonyms: DMTr-2'-O-Me-rA(Bz)-3'-Thiophosphoramidite
DMTr-2'-O-Me-rU-3'-PS2-Amidite (BRP-02834) chemical structure

DMTr-2'-O-Me-rU-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rU-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02834
Molecular Formula: C44H48N3O9PS2
Molecular Weight: 857.97
Purity: ≥98%
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InChIKey: WOJBALAHZBVIKR-QBLJBMGASA-N
SMILES: CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C44H48N3O9PS2/c1-51-35-20-16-33(17-21-35)44(32-14-8-5-9-15-32,34-18-22-36(52-2)23-19-34)54-30-37-39(40(53-3)41(55-37)47-27-24-38(48)45-43(47)50)56-57(46-25-10-11-26-46)59-29-28-58-42(49)31-12-6-4-7-13-31/h4-9,12-24,27,37,39-41H,10-11,25-26,28-30H2,1-3H3,(H,45,48,50)/t37-,39-,40-,41-,57?/m1/s1
Synonyms: DMTr-2'-O-Me-rU-3'-Thiophosphoramidite
DMTr-2'-O-Me-rG(iBu)-3'-PS2-Amidite (BRP-02835) chemical structure

DMTr-2'-O-Me-rG(iBu)-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rG(iBu)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02835
Molecular Formula: C49H55N6O9PS2
Molecular Weight: 967.11
Purity: ≥98%
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InChIKey: HZMNPGZRUUSWOU-VKFKYRIUSA-N
SMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N7CCCC7)SCCSC(=O)C8=CC=CC=C8)OC
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxy-5-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C49H55N6O9PS2/c1-32(2)44(56)52-48-51-43-40(45(57)53-48)50-31-55(43)46-42(61-5)41(64-65(54-26-12-13-27-54)67-29-28-66-47(58)33-14-8-6-9-15-33)39(63-46)30-62-49(34-16-10-7-11-17-34,35-18-22-37(59-3)23-19-35)36-20-24-38(60-4)25-21-36/h6-11,14-25,31-32,39,41-42,46H,12-13,26-30H2,1-5H3,(H2,51,52,53,56,57)/t39-,41-,42-,46-,65?/m1/s1
Synonyms: DMTr-2'-O-Me-rG(iBu)-3'-Thiophosphoramidite
DMTr-2'-O-Me-rC(Ac)-3'-PS2-Amidite (BRP-02836) chemical structure

DMTr-2'-O-Me-rC(Ac)-3'-PS2-Amidite

Description: DMTr-2'-O-Me-rC(Ac)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02836
Molecular Formula: C46H51N4O9PS2
Molecular Weight: 899.03
Purity: ≥98%
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InChIKey: CNCXGATYHORASL-SRYSXPHVSA-N
SMILES: CC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7)OC
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C46H51N4O9PS2/c1-32(51)47-40-25-28-50(45(53)48-40)43-42(56-4)41(59-60(49-26-11-12-27-49)62-30-29-61-44(52)33-13-7-5-8-14-33)39(58-43)31-57-46(34-15-9-6-10-16-34,35-17-21-37(54-2)22-18-35)36-19-23-38(55-3)24-20-36/h5-10,13-25,28,39,41-43H,11-12,26-27,29-31H2,1-4H3,(H,47,48,51,53)/t39-,41-,42-,43-,60?/m1/s1
Synonyms: DMTr-2'-O-Me-rC(Ac)-3'-Thiophosphoramidite
DMTr-2'-F-dA(Bz)-3'-PS2-Amidite (BRP-02837) chemical structure

DMTr-2'-F-dA(Bz)-3'-PS2-Amidite

Description: DMTr-2'-F-dA(Bz)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02837
Molecular Formula: C51H50FN6O7PS2
Molecular Weight: 973.09
Purity: ≥98%
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InChIKey: PPULOMKIQMTGHV-PDBKPMKASA-N
SMILES: COC1=CC=C(C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N5CCCC5)SCCSC(C6=CC=CC=C6)=O)[C@@H](F)[C@H](N7C=NC8=C(NC(C9=CC=CC=C9)=O)N=CN=C87)O4)C=C1
InChI: InChI=1S/C51H50FN6O7PS2/c1-61-40-24-20-38(21-25-40)51(37-18-10-5-11-19-37,39-22-26-41(62-2)27-23-39)63-32-42-45(65-66(57-28-12-13-29-57)68-31-30-67-50(60)36-16-8-4-9-17-36)43(52)49(64-42)58-34-55-44-46(53-33-54-47(44)58)56-48(59)35-14-6-3-7-15-35/h3-11,14-27,33-34,42-43,45,49H,12-13,28-32H2,1-2H3,(H,53,54,56,59)/t42-,43-,45-,49-,66?/m1/s1
Synonyms: DMTr-2'-F-dA(Bz)-3'-Thiophosphoramidite
DMTr-2'-F-dG(iBu)-3'-PS2-Amidite (BRP-02838) chemical structure

DMTr-2'-F-dG(iBu)-3'-PS2-Amidite

Description: DMTr-2'-F-dG(iBu)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02838
Molecular Formula: C48H52FN6O8PS2
Molecular Weight: 955.07
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: GOLSECBBKDTIRM-IMYAOLGDSA-N
SMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N7CCCC7)SCCSC(=O)C8=CC=CC=C8)F
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-fluoro-5-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C48H52FN6O8PS2/c1-31(2)43(56)52-47-51-42-40(44(57)53-47)50-30-55(42)45-39(49)41(63-64(54-25-11-12-26-54)66-28-27-65-46(58)32-13-7-5-8-14-32)38(62-45)29-61-48(33-15-9-6-10-16-33,34-17-21-36(59-3)22-18-34)35-19-23-37(60-4)24-20-35/h5-10,13-24,30-31,38-39,41,45H,11-12,25-29H2,1-4H3,(H2,51,52,53,56,57)/t38-,39-,41-,45-,64?/m1/s1
Synonyms: DMTr-2'-F-dG(iBu)-3'-Thiophosphoramidite
DMTr-2'-F-dC(Ac)-3'-PS2-Amidite (BRP-02839) chemical structure

DMTr-2'-F-dC(Ac)-3'-PS2-Amidite

Description: DMTr-2'-F-dC(Ac)-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02839
Molecular Formula: C45H48FN4O8PS2
Molecular Weight: 886.99
Purity: ≥98%
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InChIKey: YEUOGNRGLBQTSU-ZMHKPELYSA-N
SMILES: COC1=CC=C(C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N5CCCC5)SCCSC(C6=CC=CC=C6)=O)[C@@H](F)[C@H](N7C(N=C(NC(C)=O)C=C7)=O)O4)C=C1
InChI: InChI=1S/C45H48FN4O8PS2/c1-31(51)47-39-24-27-50(44(53)48-39)42-40(46)41(58-59(49-25-10-11-26-49)61-29-28-60-43(52)32-12-6-4-7-13-32)38(57-42)30-56-45(33-14-8-5-9-15-33,34-16-20-36(54-2)21-17-34)35-18-22-37(55-3)23-19-35/h4-9,12-24,27,38,40-42H,10-11,25-26,28-30H2,1-3H3,(H,47,48,51,53)/t38-,40-,41-,42-,59?/m1/s1
Synonyms: DMTr-2'-F-dC(Ac)-3'-Thiophosphoramidite
DMTr-2'-F-dU-3'-PS2-Amidite (BRP-02840) chemical structure

DMTr-2'-F-dU-3'-PS2-Amidite

Description: DMTr-2'-F-dU-3'-PS2-Amidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02840
Molecular Formula: C43H45FN3O8PS2
Molecular Weight: 845.94
Purity: ≥98%
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InChIKey: HUXZGSPNSAYIPS-CYSIDSPMSA-N
SMILES: COC1=CC=C(C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N5CCCC5)SCCSC(C6=CC=CC=C6)=O)[C@@H](F)[C@H](N7C(NC(C=C7)=O)=O)O4)C=C1
InChI: InChI=1S/C43H45FN3O8PS2/c1-51-34-19-15-32(16-20-34)43(31-13-7-4-8-14-31,33-17-21-35(52-2)22-18-33)53-29-36-39(38(44)40(54-36)47-26-23-37(48)45-42(47)50)55-56(46-24-9-10-25-46)58-28-27-57-41(49)30-11-5-3-6-12-30/h3-8,11-23,26,36,38-40H,9-10,24-25,27-29H2,1-2H3,(H,45,48,50)/t36-,38-,39-,40-,56?/m1/s1
Synonyms: DMTr-2'-F-dU-3'-Thiophosphoramidite
DMTr-2'-O-C6-rA(Bz)-3'-CE-Phosphoramidite (BRP-02841) chemical structure

DMTr-2'-O-C6-rA(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-C6-rA(Bz)-3'-CE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02841
CAS: 2642321-66-0
Molecular Formula: C53H64N7O8P
Molecular Weight: 958.09
Purity: ≥98%
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InChIKey: QGOPOAHCJYOCNH-RESYHYSISA-N
SMILES: CCCCCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-hexoxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C53H64N7O8P/c1-8-9-10-17-32-64-48-47(68-69(66-33-18-31-54)60(37(2)3)38(4)5)45(67-52(48)59-36-57-46-49(55-35-56-50(46)59)58-51(61)39-19-13-11-14-20-39)34-65-53(40-21-15-12-16-22-40,41-23-27-43(62-6)28-24-41)42-25-29-44(63-7)30-26-42/h11-16,19-30,35-38,45,47-48,52H,8-10,17-18,32-34H2,1-7H3,(H,55,56,58,61)/t45-,47-,48-,52-,69?/m1/s1
Synonyms: 2'-O-hexyl A(Bz) amidite
DMTr-2'-O-C6-rC(Bz)-3'-CE-Phosphoramidite (BRP-02842) chemical structure

DMTr-2'-O-C6-rC(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-C6-rC(Bz)-3'-CE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02842
CAS: 2642321-61-5
Molecular Formula: C52H64N5O9P
Molecular Weight: 934.07
Purity: ≥98%
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InChIKey: RFWDWXMWINZAJF-NOJOPTKUSA-N
SMILES: CCCCCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-hexoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C52H64N5O9P/c1-8-9-10-17-34-62-48-47(66-67(64-35-18-32-53)57(37(2)3)38(4)5)45(65-50(48)56-33-31-46(55-51(56)59)54-49(58)39-19-13-11-14-20-39)36-63-52(40-21-15-12-16-22-40,41-23-27-43(60-6)28-24-41)42-25-29-44(61-7)30-26-42/h11-16,19-31,33,37-38,45,47-48,50H,8-10,17-18,34-36H2,1-7H3,(H,54,55,58,59)/t45-,47-,48-,50-,67?/m1/s1
Synonyms: 2'-O-hexyl C(Bz) amidite
DMTr-2'-O-C6-rG(iBu)-3'-CE-Phosphoramidite (BRP-02843) chemical structure

DMTr-2'-O-C6-rG(iBu)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-C6-rG(iBu)-3'-CE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02843
CAS: 2642321-69-3
Molecular Formula: C50H66N7O9P
Molecular Weight: 940.07
Purity: ≥98%
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InChIKey: ZVDISOOZPNLAHG-IBSROIRUSA-N
SMILES: CCCCCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)NC(=O)C(C)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-hexoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C50H66N7O9P/c1-10-11-12-16-29-62-44-43(66-67(64-30-17-28-51)57(34(4)5)35(6)7)41(65-48(44)56-32-52-42-45(56)53-49(55-47(42)59)54-46(58)33(2)3)31-63-50(36-18-14-13-15-19-36,37-20-24-39(60-8)25-21-37)38-22-26-40(61-9)27-23-38/h13-15,18-27,32-35,41,43-44,48H,10-12,16-17,29-31H2,1-9H3,(H2,53,54,55,58,59)/t41-,43-,44-,48-,67?/m1/s1
Synonyms: 2'-O-hexyl G(iBu) amidite
6-FAM cyclohexyl Phosphoramidite (BRP-02844) chemical structure

6-FAM cyclohexyl Phosphoramidite

Description: 6-FAM cyclohexyl Phosphoramidite is a fluorescent labeling reagent used in oligonucleotide synthesis. It contains a 6-carboxyfluorescein (6-FAM) fluorophore attached to a cyclohexyl phosphoramidite moiety, enabling the incorporation of a fluorescent label at the 5' end of DNA or RNA sequences during automated solid-phase synthesis. It is widely used in molecular biology applications including DNA sequencing, PCR fragment analysis, genotyping, and fluorescence resonance energy transfer (FRET) studies.
CAT: BRP-02844
CAS: 952290-59-4
Molecular Formula: C46H56N3O10P
Molecular Weight: 841.94
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InChIKey: XQQGPIGJGDFHGJ-NAKXWQLKSA-N
SMILES: N#CCCOP(N(C(C)C)C(C)C)O[C@@H](CC1)CCC1NC(C(C=C2C34C(C=C5)=C(OC6=C3C=CC(OC(C(C)(C)C)=O)=C6)C=C5OC(C(C)(C)C)=O)=CC=C2C(O4)=O)=O
InChI: InChI=1S/C46H56N3O10P/c1-27(2)49(28(3)4)60(54-23-11-22-47)59-31-15-13-30(14-16-31)48-40(50)29-12-19-34-37(24-29)46(58-41(34)51)35-20-17-32(55-42(52)44(5,6)7)25-38(35)57-39-26-33(18-21-36(39)46)56-43(53)45(8,9)10/h12,17-21,24-28,30-31H,11,13-16,23H2,1-10H3,(H,48,50)/t30?,31-,60?
Synonyms: 6-((4-(((2-Cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)cyclohexyl)carbamoyl)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate); 6-Fluorescein cyclohexyl phosphoramidite; FAM cyclohexyl phosphoramidite, 6-isomer; FAM phosphoramidite, 6-isomer (cyclohexyl); 6-Carboxyfluorescein phosphoramidite (cyclohexyl); 6-FAM Phosphoramidite ACH

Frequently Asked Questions (FAQ)

What are phosphoramidites used for?

Phosphoramidites are activated monomers used in solid-phase DNA and RNA oligonucleotide synthesis.

RNA phosphoramidites include additional 2′-hydroxyl protecting groups, making them more sensitive to moisture and handling conditions.

Moisture can cause premature hydrolysis of phosphoramidites, reducing coupling efficiency and synthesis yield.

Yes, high-quality phosphoramidites are essential for achieving good yields in long and complex oligonucleotide sequences.

Modified and specialty phosphoramidites are commonly used to introduce functional groups or labels into oligonucleotides.

Frequently Asked Questions
* Only for research. Not suitable for any diagnostic or therapeutic use.

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