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Phosphoramidites

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2'-Modified Phosphoramidites
(594/594) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(246/246) 5'-Modified Phosphoramidites
(79/79) Arabino Phosphoramidites
(24/24) Base Protected Phosphoramidites (469/469) Dye Phosphoramidites
(63/63) Label Phosphoramidites
(81/81) Linker Phosphoramidites
(97/97) Other Phosphoramidites
(94/94) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(25/25) Spacer Phosphoramidites
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GalNAc-THA C6 phosphoramidite

Description: GalNAc-THA C6 phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02798
CAS: 2058062-52-3
Molecular Formula: C93H155N10O37P
Molecular Weight: 2036.24
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InChIKey: AQRSTPBSCQPPBQ-KAKHWKMQSA-N
CanonicalSMILES: N#CCCOP(N(C(C)C)C(C)C)OCCCCCCNC(CCCC(NC(COCCC(NCCCCCCO[C@H]1[C@H](NC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O1)=O)(COCCC(NCCCCCCO[C@@H]2O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2NC(C)=O)=O)COCCC(NCCCCCCO[C@H]3[C@H](NC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O3)=O)=O)=O
InChI: InChI=1S/C93H155N10O37P/c1-59(2)103(60(3)4)141(131-49-34-40-94)130-48-32-24-20-28-41-95-76(116)35-33-36-80(120)102-93(56-121-50-37-77(117)96-42-25-17-21-29-45-124-90-81(99-61(5)104)87(135-70(14)113)84(132-67(11)110)73(138-90)53-127-64(8)107,57-122-51-38-78(118)97-43-26-18-22-30-46-125-91-82(100-62(6)105)88(136-71(15)114)85(133-68(12)111)74(139-91)54-128-65(9)108)58-123-52-39-79(119)98-44-27-19-23-31-47-126-92-83(101-63(7)106)89(137-72(16)115)86(134-69(13)112)75(140-92)55-129-66(10)109/h59-60,73-75,81-92H,17-39,41-58H2,1-16H3,(H,95,116)(H,96,117)(H,97,118)(H,98,119)(H,99,104)(H,100,105)(H,101,106)(H,102,120)/t73-,74-,75-,81-,82-,83-,84+,85+,86+,87-,88-,89-,90-,91-,92-,141?/m1/s1
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-,2-cyanoethyl8,12,19-trioxo-14,14-bis[[3-oxo-3-[[6-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyChemicalbookranosyl]oxy]hexyl]amino]propoxy]methyl]-26-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-7,13,20-triazahexacos-1-yl ester

DMTr-2'-O-Me-rA(Bz)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rA(Bz)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02799
CAS: 1528733-91-6
Molecular Formula: C58H59N6O8PSi
Molecular Weight: 1027.2
Purity: ≥95%
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InChIKey: YPNIDBLCASOAIX-DVCONZJDSA-N
CanonicalSMILES: CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O[P@]8N9CCC[C@@H]9[C@@H](O8)C[Si](C)(C1=CC=CC=C1)C1=CC=CC=C1
IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-[[(1R,3R,3aR)-3-[[methyl(diphenyl)silyl]methyl]-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl]oxy]-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-methoxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C58H59N6O8PSi/c1-66-44-31-27-42(28-32-44)58(41-20-11-6-12-21-41,43-29-33-45(67-2)34-30-43)69-36-49-52(53(68-3)57(70-49)63-39-61-51-54(59-38-60-55(51)63)62-56(65)40-18-9-5-10-19-40)72-73-64-35-17-26-48(64)50(71-73)37-74(4,46-22-13-7-14-23-46)47-24-15-8-16-25-47/h5-16,18-25,27-34,38-39,48-50,52-53,57H,17,26,35-37H2,1-4H3,(H,59,60,62,65)/t48-,49-,50+,52-,53-,57-,73+/m1/s1

DMTr-2'-O-Me-rU-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rU-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02800
CAS: 1528733-98-3
Molecular Formula: C50H54N3O9PSi
Molecular Weight: 900.1
Purity: ≥95%
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InChIKey: ZCWZYMJOKSJYRG-BWXFLUKOSA-N
CanonicalSMILES: CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O[P@]6N7CCC[C@@H]7[C@@H](O6)C[Si](C)(C8=CC=CC=C8)C9=CC=CC=C9
IUPAC Name: 1-[(2R,3R,4R,5R)-4-[[(1R,3R,3aR)-3-[[methyl(diphenyl)silyl]methyl]-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl]oxy]-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C50H54N3O9PSi/c1-56-38-26-22-36(23-27-38)50(35-15-8-5-9-16-35,37-24-28-39(57-2)29-25-37)59-33-43-46(47(58-3)48(60-43)52-32-30-45(54)51-49(52)55)62-63-53-31-14-21-42(53)44(61-63)34-64(4,40-17-10-6-11-18-40)41-19-12-7-13-20-41/h5-13,15-20,22-30,32,42-44,46-48H,14,21,31,33-34H2,1-4H3,(H,51,54,55)/t42-,43-,44+,46-,47-,48-,63+/m1/s1

DMTr-2'-O-Me-rG(iBu)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rG(iBu)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02801
CAS: 2227139-99-1
Molecular Formula: C55H61N6O9PSi
Molecular Weight: 1009.17
Purity: ≥98%
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InChIKey: OXZJTILABONBRI-ULXZQQBCSA-N
CanonicalSMILES: CO[C@H]1[C@H](N2C=NC3=C2NC(NC(C(C)C)=O)=NC3=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@@]7O[C@@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@]%10([H])N7CCC%10
InChI: InChI=1S/C55H61N6O9PSi/c1-36(2)51(62)58-54-57-50-47(52(63)59-54)56-35-60(50)53-49(66-5)48(70-71-61-32-16-23-44(61)46(69-71)34-72(6,42-19-12-8-13-20-42)43-21-14-9-15-22-43)45(68-53)33-67-55(37-17-10-7-11-18-37,38-24-28-40(64-3)29-25-38)39-26-30-41(65-4)31-27-39/h7-15,17-22,24-31,35-36,44-46,48-49,53H,16,23,32-34H2,1-6H3,(H2,57,58,59,62,63)/t44-,45-,46+,48-,49-,53-,71+/m1/s1

DMTr-2'-O-Me-rC(Ac)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rC(Ac)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02802
Molecular Formula: C52H57N4O9PSi
Molecular Weight: 941.11
Purity: ≥98%
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InChIKey: ZIOMTJMQNMQHET-WUGSJAFOSA-N
CanonicalSMILES: CO[C@H]1[C@H](N2C(N=C(NC(C)=O)C=C2)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@@]6O[C@@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@]9([H])N6CCC9
InChI: InChI=1S/C52H57N4O9PSi/c1-36(57)53-47-31-33-55(51(58)54-47)50-49(61-4)48(65-66-56-32-15-22-44(56)46(64-66)35-67(5,42-18-11-7-12-19-42)43-20-13-8-14-21-43)45(63-50)34-62-52(37-16-9-6-10-17-37,38-23-27-40(59-2)28-24-38)39-25-29-41(60-3)30-26-39/h6-14,16-21,23-31,33,44-46,48-50H,15,22,32,34-35H2,1-5H3,(H,53,54,57,58)/t44-,45-,46+,48-,49-,50-,66+/m1/s1

DMTr-2'-O-Me-rC(Bz)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rC(Bz)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02803
Molecular Formula: C57H59N4O9PSi
Molecular Weight: 1003.18
Purity: ≥98%
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InChIKey: NWFPCSOOQFYGSM-YRMZABOLSA-N
CanonicalSMILES: CO[C@H]1[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@@]7O[C@@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@]%10([H])N7CCC%10
InChI: InChI=1S/C57H59N4O9PSi/c1-64-44-31-27-42(28-32-44)57(41-20-11-6-12-21-41,43-29-33-45(65-2)34-30-43)67-38-49-52(53(66-3)55(68-49)60-37-35-51(59-56(60)63)58-54(62)40-18-9-5-10-19-40)70-71-61-36-17-26-48(61)50(69-71)39-72(4,46-22-13-7-14-23-46)47-24-15-8-16-25-47/h5-16,18-25,27-35,37,48-50,52-53,55H,17,26,36,38-39H2,1-4H3,(H,58,59,62,63)/t48-,49-,50+,52-,53-,55-,71+/m1/s1

DMTr-2'-O-Me-rA(Bz)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rA(Bz)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02804
CAS: 1528733-90-5
Molecular Formula: C58H59N6O8PSi
Molecular Weight: 1027.20
Purity: ≥98%
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InChIKey: YPNIDBLCASOAIX-NEQFEEGOSA-N
CanonicalSMILES: CO[C@H]1[C@H](N2C3=NC=NC(NC(C4=CC=CC=C4)=O)=C3N=C2)O[C@H](COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)[C@H]1O[P@]8O[C@H](C[Si](C9=CC=CC=C9)(C)C%10=CC=CC=C%10)[C@@]%11([H])N8CCC%11
InChI: InChI=1S/C58H59N6O8PSi/c1-66-44-31-27-42(28-32-44)58(41-20-11-6-12-21-41,43-29-33-45(67-2)34-30-43)69-36-49-52(53(68-3)57(70-49)63-39-61-51-54(59-38-60-55(51)63)62-56(65)40-18-9-5-10-19-40)72-73-64-35-17-26-48(64)50(71-73)37-74(4,46-22-13-7-14-23-46)47-24-15-8-16-25-47/h5-16,18-25,27-34,38-39,48-50,52-53,57H,17,26,35-37H2,1-4H3,(H,59,60,62,65)/t48-,49+,50+,52+,53+,57+,73+/m0/s1

DMTr-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02805
CAS: 1528733-97-2
Molecular Formula: C50H54N3O9PSi
Molecular Weight: 900.05
Purity: ≥98%
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InChIKey: ZCWZYMJOKSJYRG-ISAGSOKLSA-N
CanonicalSMILES: CO[C@H]1[C@H](N2C=CC(NC2=O)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@]6O[C@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@@]9([H])N6CCC9
InChI: InChI=1S/C50H54N3O9PSi/c1-56-38-26-22-36(23-27-38)50(35-15-8-5-9-16-35,37-24-28-39(57-2)29-25-37)59-33-43-46(47(58-3)48(60-43)52-32-30-45(54)51-49(52)55)62-63-53-31-14-21-42(53)44(61-63)34-64(4,40-17-10-6-11-18-40)41-19-12-7-13-20-41/h5-13,15-20,22-30,32,42-44,46-48H,14,21,31,33-34H2,1-4H3,(H,51,54,55)/t42-,43+,44+,46+,47+,48+,63+/m0/s1

DMTr-2'-O-Me-rG(iBu)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rG(iBu)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02806
CAS: 2227139-95-7
Molecular Formula: C55H61N6O9PSi
Molecular Weight: 1009.17
Purity: ≥98%
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InChIKey: OXZJTILABONBRI-FFAWFTCZSA-N
CanonicalSMILES: CO[C@H]1[C@H](N2C=NC3=C2NC(NC(C(C)C)=O)=NC3=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@]7O[C@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@@]%10([H])N7CCC%10
InChI: InChI=1S/C55H61N6O9PSi/c1-36(2)51(62)58-54-57-50-47(52(63)59-54)56-35-60(50)53-49(66-5)48(70-71-61-32-16-23-44(61)46(69-71)34-72(6,42-19-12-8-13-20-42)43-21-14-9-15-22-43)45(68-53)33-67-55(37-17-10-7-11-18-37,38-24-28-40(64-3)29-25-38)39-26-30-41(65-4)31-27-39/h7-15,17-22,24-31,35-36,44-46,48-49,53H,16,23,32-34H2,1-6H3,(H2,57,58,59,62,63)/t44-,45+,46+,48+,49+,53+,71+/m0/s1

DMTr-2'-O-Me-rC(Ac)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rC(Ac)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02807
Molecular Formula: C52H57N4O9PSi
Molecular Weight: 941.11
Purity: ≥98%
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InChIKey: ZIOMTJMQNMQHET-QMSJJSGGSA-N
CanonicalSMILES: CO[C@H]1[C@H](N2C(N=C(NC(C)=O)C=C2)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@]6O[C@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@@]9([H])N6CCC9
InChI: InChI=1S/C52H57N4O9PSi/c1-36(57)53-47-31-33-55(51(58)54-47)50-49(61-4)48(65-66-56-32-15-22-44(56)46(64-66)35-67(5,42-18-11-7-12-19-42)43-20-13-8-14-21-43)45(63-50)34-62-52(37-16-9-6-10-17-37,38-23-27-40(59-2)28-24-38)39-25-29-41(60-3)30-26-39/h6-14,16-21,23-31,33,44-46,48-50H,15,22,32,34-35H2,1-5H3,(H,53,54,57,58)/t44-,45+,46+,48+,49+,50+,66+/m0/s1

DMTr-2'-O-Me-rC(Bz)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rC(Bz)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02808
Molecular Formula: C57H59N4O9PSi
Molecular Weight: 1003.18
Purity: ≥98%
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InChIKey: NWFPCSOOQFYGSM-XPYGNBTKSA-N
CanonicalSMILES: CO[C@H]1[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@]7O[C@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@@]%10([H])N7CCC%10
InChI: InChI=1S/C57H59N4O9PSi/c1-64-44-31-27-42(28-32-44)57(41-20-11-6-12-21-41,43-29-33-45(65-2)34-30-43)67-38-49-52(53(66-3)55(68-49)60-37-35-51(59-56(60)63)58-54(62)40-18-9-5-10-19-40)70-71-61-36-17-26-48(61)50(69-71)39-72(4,46-22-13-7-14-23-46)47-24-15-8-16-25-47/h5-16,18-25,27-35,37,48-50,52-53,55H,17,26,36,38-39H2,1-4H3,(H,58,59,62,63)/t48-,49+,50+,52+,53+,55+,71+/m0/s1

DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02809
CAS: 1528734-00-0
Molecular Formula: C57H56FN6O7PSi
Molecular Weight: 1015.15
Purity: ≥98%
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InChIKey: JFBTVNIZTJNYIU-FMEBJQHZSA-N
CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)F)O[P@]8N9CCC[C@@H]9[C@@H](O8)C[Si](C)(C1=CC=CC=C1)C1=CC=CC=C1
IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-[[(1R,3R,3aR)-3-[[methyl(diphenyl)silyl]methyl]-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl]oxy]-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluorooxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C57H56FN6O7PSi/c1-66-43-30-26-41(27-31-43)57(40-19-10-5-11-20-40,42-28-32-44(67-2)33-29-42)68-35-48-52(50(58)56(69-48)63-38-61-51-53(59-37-60-54(51)63)62-55(65)39-17-8-4-9-18-39)71-72-64-34-16-25-47(64)49(70-72)36-73(3,45-21-12-6-13-22-45)46-23-14-7-15-24-46/h4-15,17-24,26-33,37-38,47-50,52,56H,16,25,34-36H2,1-3H3,(H,59,60,62,65)/t47-,48-,49+,50-,52-,56-,72+/m1/s1

DMTr-2'-F-dG(iBu)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dG(iBu)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02810
CAS: 2227140-01-2
Molecular Formula: C54H58FN6O8PSi
Molecular Weight: 997.13
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: GSSYTHNLCHZVRD-NSBBQIGSSA-N
CanonicalSMILES: O=C1N=C(NC(C(C)C)=O)NC2=C1N=CN2[C@@H]3O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@@H](O[P@@]7O[C@@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@]%10([H])N7CCC%10)[C@H]3F
InChI: InChI=1S/C54H58FN6O8PSi/c1-35(2)50(62)58-53-57-49-47(51(63)59-53)56-34-60(49)52-46(55)48(69-70-61-31-15-22-43(61)45(68-70)33-71(5,41-18-11-7-12-19-41)42-20-13-8-14-21-42)44(67-52)32-66-54(36-16-9-6-10-17-36,37-23-27-39(64-3)28-24-37)38-25-29-40(65-4)30-26-38/h6-14,16-21,23-30,34-35,43-46,48,52H,15,22,31-33H2,1-5H3,(H2,57,58,59,62,63)/t43-,44-,45+,46-,48-,52-,70+/m1/s1

DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02811
Molecular Formula: C56H56FN4O8PSi
Molecular Weight: 991.14
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: RBSWGXQNQSYSLO-VWPIAUDXSA-N
CanonicalSMILES: F[C@H]1[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@@]7O[C@@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@]%10([H])N7CCC%10
InChI: InChI=1S/C56H56FN4O8PSi/c1-64-43-30-26-41(27-31-43)56(40-19-10-5-11-20-40,42-28-32-44(65-2)33-29-42)66-37-48-52(51(57)54(67-48)60-36-34-50(59-55(60)63)58-53(62)39-17-8-4-9-18-39)69-70-61-35-16-25-47(61)49(68-70)38-71(3,45-21-12-6-13-22-45)46-23-14-7-15-24-46/h4-15,17-24,26-34,36,47-49,51-52,54H,16,25,35,37-38H2,1-3H3,(H,58,59,62,63)/t47-,48-,49+,51-,52-,54-,70+/m1/s1

DMTr-2'-F-dC(Ac)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dC(Ac)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02812
Molecular Formula: C51H54FN4O8PSi
Molecular Weight: 929.07
Purity: ≥98%
Size Price Stock Quantity
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Storage: Store at -20 °C
InChIKey: VQNPYPMNXZDQEG-SZOVNFBWSA-N
CanonicalSMILES: F[C@H]1[C@H](N2C(N=C(NC(C)=O)C=C2)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@@]6O[C@@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@]9([H])N6CCC9
InChI: InChI=1S/C51H54FN4O8PSi/c1-35(57)53-46-30-32-55(50(58)54-46)49-47(52)48(64-65-56-31-14-21-43(56)45(63-65)34-66(4,41-17-10-6-11-18-41)42-19-12-7-13-20-42)44(62-49)33-61-51(36-15-8-5-9-16-36,37-22-26-39(59-2)27-23-37)38-24-28-40(60-3)29-25-38/h5-13,15-20,22-30,32,43-45,47-49H,14,21,31,33-34H2,1-4H3,(H,53,54,57,58)/t43-,44-,45+,47-,48-,49-,65+/m1/s1

DMTr-2'-F-dU-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dU-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02813
CAS: 1528734-09-9
Molecular Formula: C49H51FN3O8PSi
Molecular Weight: 888.00
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: SWLDICAIEKIRDG-SAYIXLIESA-N
CanonicalSMILES: F[C@H]1[C@H](N2C(NC(C=C2)=O)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@@]6O[C@@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@]9([H])N6CCC9
InChI: InChI=1S/C49H51FN3O8PSi/c1-56-37-25-21-35(22-26-37)49(34-14-7-4-8-15-34,36-23-27-38(57-2)28-24-36)58-32-42-46(45(50)47(59-42)52-31-29-44(54)51-48(52)55)61-62-53-30-13-20-41(53)43(60-62)33-63(3,39-16-9-5-10-17-39)40-18-11-6-12-19-40/h4-12,14-19,21-29,31,41-43,45-47H,13,20,30,32-33H2,1-3H3,(H,51,54,55)/t41-,42-,43+,45-,46-,47-,62+/m1/s1

DMTr-2'-F-dA(Bz)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dA(Bz)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02814
CAS: 1528733-99-4
Molecular Formula: C57H56FN6O7PSi
Molecular Weight: 1015.15
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: JFBTVNIZTJNYIU-KGYNQPFNSA-N
CanonicalSMILES: F[C@H]1[C@H](N2C3=NC=NC(NC(C4=CC=CC=C4)=O)=C3N=C2)O[C@H](COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)[C@H]1O[P@]8O[C@H](C[Si](C9=CC=CC=C9)(C)C%10=CC=CC=C%10)[C@@]%11([H])N8CCC%11
InChI: InChI=1S/C57H56FN6O7PSi/c1-66-43-30-26-41(27-31-43)57(40-19-10-5-11-20-40,42-28-32-44(67-2)33-29-42)68-35-48-52(50(58)56(69-48)63-38-61-51-53(59-37-60-54(51)63)62-55(65)39-17-8-4-9-18-39)71-72-64-34-16-25-47(64)49(70-72)36-73(3,45-21-12-6-13-22-45)46-23-14-7-15-24-46/h4-15,17-24,26-33,37-38,47-50,52,56H,16,25,34-36H2,1-3H3,(H,59,60,62,65)/t47-,48+,49+,50+,52+,56+,72+/m0/s1

DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02815
CAS: 2227139-97-9
Molecular Formula: C54H58FN6O8PSi
Molecular Weight: 997.13
Purity: ≥98%
Size Price Stock Quantity
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Storage: Store at -20 °C
InChIKey: GSSYTHNLCHZVRD-ABIOHNQMSA-N
CanonicalSMILES: F[C@H]1[C@H](N2C=NC3=C2NC(NC(C(C)C)=O)=NC3=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@]7O[C@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@@]%10([H])N7CCC%10
InChI: InChI=1S/C54H58FN6O8PSi/c1-35(2)50(62)58-53-57-49-47(51(63)59-53)56-34-60(49)52-46(55)48(69-70-61-31-15-22-43(61)45(68-70)33-71(5,41-18-11-7-12-19-41)42-20-13-8-14-21-42)44(67-52)32-66-54(36-16-9-6-10-17-36,37-23-27-39(64-3)28-24-37)38-25-29-40(65-4)30-26-38/h6-14,16-21,23-30,34-35,43-46,48,52H,15,22,31-33H2,1-5H3,(H2,57,58,59,62,63)/t43-,44+,45+,46+,48+,52+,70+/m0/s1

DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02816
Molecular Formula: C56H56FN4O8PSi
Molecular Weight: 991.14
Purity: ≥98%
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at -20 °C
InChIKey: RBSWGXQNQSYSLO-IPSKWSLCSA-N
CanonicalSMILES: F[C@H]1[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@]7O[C@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@@]%10([H])N7CCC%10
InChI: InChI=1S/C56H56FN4O8PSi/c1-64-43-30-26-41(27-31-43)56(40-19-10-5-11-20-40,42-28-32-44(65-2)33-29-42)66-37-48-52(51(57)54(67-48)60-36-34-50(59-55(60)63)58-53(62)39-17-8-4-9-18-39)69-70-61-35-16-25-47(61)49(68-70)38-71(3,45-21-12-6-13-22-45)46-23-14-7-15-24-46/h4-15,17-24,26-34,36,47-49,51-52,54H,16,25,35,37-38H2,1-3H3,(H,58,59,62,63)/t47-,48+,49+,51+,52+,54+,70+/m0/s1

DMTr-2'-F-dC(Ac)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dC(Ac)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02817
Molecular Formula: C51H54FN4O8PSi
Molecular Weight: 929.07
Purity: ≥98%
Size Price Stock Quantity
-- -- --
Inquiry   
Storage: Store at -20 °C
InChIKey: VQNPYPMNXZDQEG-NMXYBMEISA-N
CanonicalSMILES: F[C@H]1[C@H](N2C(N=C(NC(C)=O)C=C2)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@]6O[C@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@@]9([H])N6CCC9
InChI: InChI=1S/C51H54FN4O8PSi/c1-35(57)53-46-30-32-55(50(58)54-46)49-47(52)48(64-65-56-31-14-21-43(56)45(63-65)34-66(4,41-17-10-6-11-18-41)42-19-12-7-13-20-42)44(62-49)33-61-51(36-15-8-5-9-16-36,37-22-26-39(59-2)27-23-37)38-24-28-40(60-3)29-25-38/h5-13,15-20,22-30,32,43-45,47-49H,14,21,31,33-34H2,1-4H3,(H,53,54,57,58)/t43-,44+,45+,47+,48+,49+,65+/m0/s1

Frequently Asked Questions (FAQ)

What are phosphoramidites used for?

Phosphoramidites are activated monomers used in solid-phase DNA and RNA oligonucleotide synthesis.

What is the difference between DNA and RNA phosphoramidites?

RNA phosphoramidites include additional 2′-hydroxyl protecting groups, making them more sensitive to moisture and handling conditions.

Why is moisture control important for phosphoramidites?

Moisture can cause premature hydrolysis of phosphoramidites, reducing coupling efficiency and synthesis yield.

Can phosphoramidites be used for long oligonucleotide synthesis?

Yes, high-quality phosphoramidites are essential for achieving good yields in long and complex oligonucleotide sequences.

Are modified phosphoramidites available for custom oligos?

Modified and specialty phosphoramidites are commonly used to introduce functional groups or labels into oligonucleotides.

* Only for research. Not suitable for any diagnostic or therapeutic use.

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