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Phosphoramidites

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2'-Modified Phosphoramidites
(594/594) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(246/246) 5'-Modified Phosphoramidites
(79/79) Arabino Phosphoramidites
(24/24) Base Protected Phosphoramidites (469/469) Dye Phosphoramidites
(72/72) Label Phosphoramidites
(86/86) Linker Phosphoramidites
(113/113) Other Phosphoramidites
(94/94) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(25/25) Spacer Phosphoramidites
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DMTr-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite (BRP-02805) chemical structure

DMTr-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rU-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02805
CAS: 1528733-97-2
Molecular Formula: C50H54N3O9PSi
Molecular Weight: 900.05
Purity: ≥98%
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InChIKey: ZCWZYMJOKSJYRG-ISAGSOKLSA-N
SMILES: CO[C@H]1[C@H](N2C=CC(NC2=O)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@]6O[C@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@@]9([H])N6CCC9
InChI: InChI=1S/C50H54N3O9PSi/c1-56-38-26-22-36(23-27-38)50(35-15-8-5-9-16-35,37-24-28-39(57-2)29-25-37)59-33-43-46(47(58-3)48(60-43)52-32-30-45(54)51-49(52)55)62-63-53-31-14-21-42(53)44(61-63)34-64(4,40-17-10-6-11-18-40)41-19-12-7-13-20-41/h5-13,15-20,22-30,32,42-44,46-48H,14,21,31,33-34H2,1-4H3,(H,51,54,55)/t42-,43+,44+,46+,47+,48+,63+/m0/s1
DMTr-2'-O-Me-rG(iBu)-3'-(L)-DPSE-Phosphoramidite (BRP-02806) chemical structure

DMTr-2'-O-Me-rG(iBu)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rG(iBu)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02806
CAS: 2227139-95-7
Molecular Formula: C55H61N6O9PSi
Molecular Weight: 1009.17
Purity: ≥98%
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InChIKey: OXZJTILABONBRI-FFAWFTCZSA-N
SMILES: CO[C@H]1[C@H](N2C=NC3=C2NC(NC(C(C)C)=O)=NC3=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@]7O[C@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@@]%10([H])N7CCC%10
InChI: InChI=1S/C55H61N6O9PSi/c1-36(2)51(62)58-54-57-50-47(52(63)59-54)56-35-60(50)53-49(66-5)48(70-71-61-32-16-23-44(61)46(69-71)34-72(6,42-19-12-8-13-20-42)43-21-14-9-15-22-43)45(68-53)33-67-55(37-17-10-7-11-18-37,38-24-28-40(64-3)29-25-38)39-26-30-41(65-4)31-27-39/h7-15,17-22,24-31,35-36,44-46,48-49,53H,16,23,32-34H2,1-6H3,(H2,57,58,59,62,63)/t44-,45+,46+,48+,49+,53+,71+/m0/s1
DMTr-2'-O-Me-rC(Ac)-3'-(L)-DPSE-Phosphoramidite (BRP-02807) chemical structure

DMTr-2'-O-Me-rC(Ac)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rC(Ac)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02807
Molecular Formula: C52H57N4O9PSi
Molecular Weight: 941.11
Purity: ≥98%
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InChIKey: ZIOMTJMQNMQHET-QMSJJSGGSA-N
SMILES: CO[C@H]1[C@H](N2C(N=C(NC(C)=O)C=C2)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@]6O[C@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@@]9([H])N6CCC9
InChI: InChI=1S/C52H57N4O9PSi/c1-36(57)53-47-31-33-55(51(58)54-47)50-49(61-4)48(65-66-56-32-15-22-44(56)46(64-66)35-67(5,42-18-11-7-12-19-42)43-20-13-8-14-21-43)45(63-50)34-62-52(37-16-9-6-10-17-37,38-23-27-40(59-2)28-24-38)39-25-29-41(60-3)30-26-39/h6-14,16-21,23-31,33,44-46,48-50H,15,22,32,34-35H2,1-5H3,(H,53,54,57,58)/t44-,45+,46+,48+,49+,50+,66+/m0/s1
DMTr-2'-O-Me-rC(Bz)-3'-(L)-DPSE-Phosphoramidite (BRP-02808) chemical structure

DMTr-2'-O-Me-rC(Bz)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-O-Me-rC(Bz)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02808
Molecular Formula: C57H59N4O9PSi
Molecular Weight: 1003.18
Purity: ≥98%
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InChIKey: NWFPCSOOQFYGSM-XPYGNBTKSA-N
SMILES: CO[C@H]1[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@]7O[C@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@@]%10([H])N7CCC%10
InChI: InChI=1S/C57H59N4O9PSi/c1-64-44-31-27-42(28-32-44)57(41-20-11-6-12-21-41,43-29-33-45(65-2)34-30-43)67-38-49-52(53(66-3)55(68-49)60-37-35-51(59-56(60)63)58-54(62)40-18-9-5-10-19-40)70-71-61-36-17-26-48(61)50(69-71)39-72(4,46-22-13-7-14-23-46)47-24-15-8-16-25-47/h5-16,18-25,27-35,37,48-50,52-53,55H,17,26,36,38-39H2,1-4H3,(H,58,59,62,63)/t48-,49+,50+,52+,53+,55+,71+/m0/s1
DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-Phosphoramidite (BRP-02809) chemical structure

DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02809
CAS: 1528734-00-0
Molecular Formula: C57H56FN6O7PSi
Molecular Weight: 1015.15
Purity: ≥98%
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InChIKey: JFBTVNIZTJNYIU-FMEBJQHZSA-N
SMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)F)O[P@]8N9CCC[C@@H]9[C@@H](O8)C[Si](C)(C1=CC=CC=C1)C1=CC=CC=C1
IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-[[(1R,3R,3aR)-3-[[methyl(diphenyl)silyl]methyl]-3a,4,5,6-tetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl]oxy]-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluorooxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C57H56FN6O7PSi/c1-66-43-30-26-41(27-31-43)57(40-19-10-5-11-20-40,42-28-32-44(67-2)33-29-42)68-35-48-52(50(58)56(69-48)63-38-61-51-53(59-37-60-54(51)63)62-55(65)39-17-8-4-9-18-39)71-72-64-34-16-25-47(64)49(70-72)36-73(3,45-21-12-6-13-22-45)46-23-14-7-15-24-46/h4-15,17-24,26-33,37-38,47-50,52,56H,16,25,34-36H2,1-3H3,(H,59,60,62,65)/t47-,48-,49+,50-,52-,56-,72+/m1/s1
DMTr-2'-F-dG(iBu)-3'-(D)-DPSE-Phosphoramidite (BRP-02810) chemical structure

DMTr-2'-F-dG(iBu)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dG(iBu)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02810
CAS: 2227140-01-2
Molecular Formula: C54H58FN6O8PSi
Molecular Weight: 997.13
Purity: ≥98%
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InChIKey: GSSYTHNLCHZVRD-NSBBQIGSSA-N
SMILES: O=C1N=C(NC(C(C)C)=O)NC2=C1N=CN2[C@@H]3O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@@H](O[P@@]7O[C@@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@]%10([H])N7CCC%10)[C@H]3F
InChI: InChI=1S/C54H58FN6O8PSi/c1-35(2)50(62)58-53-57-49-47(51(63)59-53)56-34-60(49)52-46(55)48(69-70-61-31-15-22-43(61)45(68-70)33-71(5,41-18-11-7-12-19-41)42-20-13-8-14-21-42)44(67-52)32-66-54(36-16-9-6-10-17-36,37-23-27-39(64-3)28-24-37)38-25-29-40(65-4)30-26-38/h6-14,16-21,23-30,34-35,43-46,48,52H,15,22,31-33H2,1-5H3,(H2,57,58,59,62,63)/t43-,44-,45+,46-,48-,52-,70+/m1/s1
DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite (BRP-02811) chemical structure

DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02811
Molecular Formula: C56H56FN4O8PSi
Molecular Weight: 991.14
Purity: ≥98%
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InChIKey: RBSWGXQNQSYSLO-VWPIAUDXSA-N
SMILES: F[C@H]1[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@@]7O[C@@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@]%10([H])N7CCC%10
InChI: InChI=1S/C56H56FN4O8PSi/c1-64-43-30-26-41(27-31-43)56(40-19-10-5-11-20-40,42-28-32-44(65-2)33-29-42)66-37-48-52(51(57)54(67-48)60-36-34-50(59-55(60)63)58-53(62)39-17-8-4-9-18-39)69-70-61-35-16-25-47(61)49(68-70)38-71(3,45-21-12-6-13-22-45)46-23-14-7-15-24-46/h4-15,17-24,26-34,36,47-49,51-52,54H,16,25,35,37-38H2,1-3H3,(H,58,59,62,63)/t47-,48-,49+,51-,52-,54-,70+/m1/s1
DMTr-2'-F-dC(Ac)-3'-(D)-DPSE-Phosphoramidite (BRP-02812) chemical structure

DMTr-2'-F-dC(Ac)-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dC(Ac)-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02812
Molecular Formula: C51H54FN4O8PSi
Molecular Weight: 929.07
Purity: ≥98%
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InChIKey: VQNPYPMNXZDQEG-SZOVNFBWSA-N
SMILES: F[C@H]1[C@H](N2C(N=C(NC(C)=O)C=C2)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@@]6O[C@@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@]9([H])N6CCC9
InChI: InChI=1S/C51H54FN4O8PSi/c1-35(57)53-46-30-32-55(50(58)54-46)49-47(52)48(64-65-56-31-14-21-43(56)45(63-65)34-66(4,41-17-10-6-11-18-41)42-19-12-7-13-20-42)44(62-49)33-61-51(36-15-8-5-9-16-36,37-22-26-39(59-2)27-23-37)38-24-28-40(60-3)29-25-38/h5-13,15-20,22-30,32,43-45,47-49H,14,21,31,33-34H2,1-4H3,(H,53,54,57,58)/t43-,44-,45+,47-,48-,49-,65+/m1/s1
DMTr-2'-F-dU-3'-(D)-DPSE-Phosphoramidite (BRP-02813) chemical structure

DMTr-2'-F-dU-3'-(D)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dU-3'-(D)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02813
CAS: 1528734-09-9
Molecular Formula: C49H51FN3O8PSi
Molecular Weight: 888.00
Purity: ≥98%
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InChIKey: SWLDICAIEKIRDG-SAYIXLIESA-N
SMILES: F[C@H]1[C@H](N2C(NC(C=C2)=O)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@@]6O[C@@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@]9([H])N6CCC9
InChI: InChI=1S/C49H51FN3O8PSi/c1-56-37-25-21-35(22-26-37)49(34-14-7-4-8-15-34,36-23-27-38(57-2)28-24-36)58-32-42-46(45(50)47(59-42)52-31-29-44(54)51-48(52)55)61-62-53-30-13-20-41(53)43(60-62)33-63(3,39-16-9-5-10-17-39)40-18-11-6-12-19-40/h4-12,14-19,21-29,31,41-43,45-47H,13,20,30,32-33H2,1-3H3,(H,51,54,55)/t41-,42-,43+,45-,46-,47-,62+/m1/s1
DMTr-2'-F-dA(Bz)-3'-(L)-DPSE-Phosphoramidite (BRP-02814) chemical structure

DMTr-2'-F-dA(Bz)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dA(Bz)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02814
CAS: 1528733-99-4
Molecular Formula: C57H56FN6O7PSi
Molecular Weight: 1015.15
Purity: ≥98%
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InChIKey: JFBTVNIZTJNYIU-KGYNQPFNSA-N
SMILES: F[C@H]1[C@H](N2C3=NC=NC(NC(C4=CC=CC=C4)=O)=C3N=C2)O[C@H](COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)[C@H]1O[P@]8O[C@H](C[Si](C9=CC=CC=C9)(C)C%10=CC=CC=C%10)[C@@]%11([H])N8CCC%11
InChI: InChI=1S/C57H56FN6O7PSi/c1-66-43-30-26-41(27-31-43)57(40-19-10-5-11-20-40,42-28-32-44(67-2)33-29-42)68-35-48-52(50(58)56(69-48)63-38-61-51-53(59-37-60-54(51)63)62-55(65)39-17-8-4-9-18-39)71-72-64-34-16-25-47(64)49(70-72)36-73(3,45-21-12-6-13-22-45)46-23-14-7-15-24-46/h4-15,17-24,26-33,37-38,47-50,52,56H,16,25,34-36H2,1-3H3,(H,59,60,62,65)/t47-,48+,49+,50+,52+,56+,72+/m0/s1
DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite (BRP-02815) chemical structure

DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02815
CAS: 2227139-97-9
Molecular Formula: C54H58FN6O8PSi
Molecular Weight: 997.13
Purity: ≥98%
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InChIKey: GSSYTHNLCHZVRD-ABIOHNQMSA-N
SMILES: F[C@H]1[C@H](N2C=NC3=C2NC(NC(C(C)C)=O)=NC3=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@]7O[C@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@@]%10([H])N7CCC%10
InChI: InChI=1S/C54H58FN6O8PSi/c1-35(2)50(62)58-53-57-49-47(51(63)59-53)56-34-60(49)52-46(55)48(69-70-61-31-15-22-43(61)45(68-70)33-71(5,41-18-11-7-12-19-41)42-20-13-8-14-21-42)44(67-52)32-66-54(36-16-9-6-10-17-36,37-23-27-39(64-3)28-24-37)38-25-29-40(65-4)30-26-38/h6-14,16-21,23-30,34-35,43-46,48,52H,15,22,31-33H2,1-5H3,(H2,57,58,59,62,63)/t43-,44+,45+,46+,48+,52+,70+/m0/s1
DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite (BRP-02816) chemical structure

DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02816
Molecular Formula: C56H56FN4O8PSi
Molecular Weight: 991.14
Purity: ≥98%
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InChIKey: RBSWGXQNQSYSLO-IPSKWSLCSA-N
SMILES: F[C@H]1[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@H]1O[P@]7O[C@H](C[Si](C8=CC=CC=C8)(C)C9=CC=CC=C9)[C@@]%10([H])N7CCC%10
InChI: InChI=1S/C56H56FN4O8PSi/c1-64-43-30-26-41(27-31-43)56(40-19-10-5-11-20-40,42-28-32-44(65-2)33-29-42)66-37-48-52(51(57)54(67-48)60-36-34-50(59-55(60)63)58-53(62)39-17-8-4-9-18-39)69-70-61-35-16-25-47(61)49(68-70)38-71(3,45-21-12-6-13-22-45)46-23-14-7-15-24-46/h4-15,17-24,26-34,36,47-49,51-52,54H,16,25,35,37-38H2,1-3H3,(H,58,59,62,63)/t47-,48+,49+,51+,52+,54+,70+/m0/s1
DMTr-2'-F-dC(Ac)-3'-(L)-DPSE-Phosphoramidite (BRP-02817) chemical structure

DMTr-2'-F-dC(Ac)-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dC(Ac)-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02817
Molecular Formula: C51H54FN4O8PSi
Molecular Weight: 929.07
Purity: ≥98%
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InChIKey: VQNPYPMNXZDQEG-NMXYBMEISA-N
SMILES: F[C@H]1[C@H](N2C(N=C(NC(C)=O)C=C2)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@]6O[C@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@@]9([H])N6CCC9
InChI: InChI=1S/C51H54FN4O8PSi/c1-35(57)53-46-30-32-55(50(58)54-46)49-47(52)48(64-65-56-31-14-21-43(56)45(63-65)34-66(4,41-17-10-6-11-18-41)42-19-12-7-13-20-42)44(62-49)33-61-51(36-15-8-5-9-16-36,37-22-26-39(59-2)27-23-37)38-24-28-40(60-3)29-25-38/h5-13,15-20,22-30,32,43-45,47-49H,14,21,31,33-34H2,1-4H3,(H,53,54,57,58)/t43-,44+,45+,47+,48+,49+,65+/m0/s1
DMTr-2'-F-dU-3'-(L)-DPSE-Phosphoramidite (BRP-02818) chemical structure

DMTr-2'-F-dU-3'-(L)-DPSE-Phosphoramidite

Description: DMTr-2'-F-dU-3'-(L)-DPSE-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02818
CAS: 1528734-08-8
Molecular Formula: C49H51FN3O8PSi
Molecular Weight: 888.00
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: SWLDICAIEKIRDG-ULMIAZCZSA-N
SMILES: F[C@H]1[C@H](N2C(NC(C=C2)=O)=O)O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@H]1O[P@]6O[C@H](C[Si](C7=CC=CC=C7)(C)C8=CC=CC=C8)[C@@]9([H])N6CCC9
InChI: InChI=1S/C49H51FN3O8PSi/c1-56-37-25-21-35(22-26-37)49(34-14-7-4-8-15-34,36-23-27-38(57-2)28-24-36)58-32-42-46(45(50)47(59-42)52-31-29-44(54)51-48(52)55)61-62-53-30-13-20-41(53)43(60-62)33-63(3,39-16-9-5-10-17-39)40-18-11-6-12-19-40/h4-12,14-19,21-29,31,41-43,45-47H,13,20,30,32-33H2,1-3H3,(H,51,54,55)/t41-,42+,43+,45+,46+,47+,62+/m0/s1
DMTr-2'-O-Me-rG(iBu)-3'-(D)-PSM-Phosphoramidite (BRP-02819) chemical structure

DMTr-2'-O-Me-rG(iBu)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rG(iBu)-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02819
Molecular Formula: C48H53N6O11PS
Molecular Weight: 953.02
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: QCPFOYJTUFIVGR-BKXFETEPSA-N
SMILES: CC(C)C(NC(N1)=NC2=C(N=CN2[C@@H]3O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@@H](O[P@@]7O[C@@H](CS(=O)(C8=CC=CC=C8)=O)[C@]9([H])N7CCC9)[C@H]3OC)C1=O)=O
InChI: InChI=1S/C48H53N6O11PS/c1-30(2)44(55)51-47-50-43-40(45(56)52-47)49-29-53(43)46-42(61-5)41(65-66-54-26-12-17-37(54)39(64-66)28-67(57,58)36-15-10-7-11-16-36)38(63-46)27-62-48(31-13-8-6-9-14-31,32-18-22-34(59-3)23-19-32)33-20-24-35(60-4)25-21-33/h6-11,13-16,18-25,29-30,37-39,41-42,46H,12,17,26-28H2,1-5H3,(H2,50,51,52,55,56)/t37-,38-,39+,41-,42-,46-,66+/m1/s1
DMTr-2'-O-Me-rC(Ac)-3'-(D)-PSM-Phosphoramidite (BRP-02820) chemical structure

DMTr-2'-O-Me-rC(Ac)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rC(Ac)-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02820
Molecular Formula: C45H49N4O11PS
Molecular Weight: 884.94
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: AOAKYUMILRMJOU-LFPDPUHYSA-N
SMILES: CC(NC(C=CN1[C@@H]2O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@@H](O[P@@]6O[C@@H](CS(=O)(C7=CC=CC=C7)=O)[C@]8([H])N6CCC8)[C@H]2OC)=NC1=O)=O
InChI: InChI=1S/C45H49N4O11PS/c1-30(50)46-40-25-27-48(44(51)47-40)43-42(56-4)41(60-61-49-26-11-16-37(49)39(59-61)29-62(52,53)36-14-9-6-10-15-36)38(58-43)28-57-45(31-12-7-5-8-13-31,32-17-21-34(54-2)22-18-32)33-19-23-35(55-3)24-20-33/h5-10,12-15,17-25,27,37-39,41-43H,11,16,26,28-29H2,1-4H3,(H,46,47,50,51)/t37-,38-,39+,41-,42-,43-,61+/m1/s1
DMTr-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite (BRP-02821) chemical structure

DMTr-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rU-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02821
Molecular Formula: C43H46N3O11PS
Molecular Weight: 843.88
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: WALZCFCZIWHBMO-UDOAYZSSSA-N
SMILES: O=C1NC(C=CN1[C@@H]2O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5)[C@@H](O[P@@]6O[C@@H](CS(=O)(C7=CC=CC=C7)=O)[C@]8([H])N6CCC8)[C@H]2OC)=O
InChI: InChI=1S/C43H46N3O11PS/c1-51-32-20-16-30(17-21-32)43(29-11-6-4-7-12-29,31-18-22-33(52-2)23-19-31)54-27-36-39(40(53-3)41(55-36)45-26-24-38(47)44-42(45)48)57-58-46-25-10-15-35(46)37(56-58)28-59(49,50)34-13-8-5-9-14-34/h4-9,11-14,16-24,26,35-37,39-41H,10,15,25,27-28H2,1-3H3,(H,44,47,48)/t35-,36-,37+,39-,40-,41-,58+/m1/s1
DMTr-2'-F-dA(Bz)-3'-(D)-PSM-Phosphoramidite (BRP-02822) chemical structure

DMTr-2'-F-dA(Bz)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-F-dA(Bz)-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02822
Molecular Formula: C50H48FN6O9PS
Molecular Weight: 959.00
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: XNKVSLALPYQTFX-PYSJVOCBSA-N
SMILES: O=S(C[C@H]1[C@](CCC2)([H])N2[P@](O[C@H]3[C@@H](F)[C@H](N4C=NC5=C(NC(C6=CC=CC=C6)=O)N=CN=C54)O[C@@H]3COC(C7=CC=C(OC)C=C7)(C8=CC=C(OC)C=C8)C9=CC=CC=C9)O1)(C%10=CC=CC=C%10)=O
InChI: InChI=1S/C50H48FN6O9PS/c1-61-37-24-20-35(21-25-37)50(34-15-8-4-9-16-34,36-22-26-38(62-2)27-23-36)63-29-41-45(66-67-57-28-12-19-40(57)42(65-67)30-68(59,60)39-17-10-5-11-18-39)43(51)49(64-41)56-32-54-44-46(52-31-53-47(44)56)55-48(58)33-13-6-3-7-14-33/h3-11,13-18,20-27,31-32,40-43,45,49H,12,19,28-30H2,1-2H3,(H,52,53,55,58)/t40-,41-,42+,43-,45-,49-,67+/m1/s1
DMTr-2'-F-dG(iBu)-3'-(D)-PSM-Phosphoramidite (BRP-02823) chemical structure

DMTr-2'-F-dG(iBu)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-F-dG(iBu)-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02823
Molecular Formula: C47H50FN6O10PS
Molecular Weight: 940.98
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: VGPMRAFQMYMCJH-IXGNQCOLSA-N
SMILES: CC(C)C(NC(N1)=NC2=C(N=CN2[C@@H]3O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@@H](O[P@@]7O[C@@H](CS(=O)(C8=CC=CC=C8)=O)[C@]9([H])N7CCC9)[C@H]3F)C1=O)=O
InChI: InChI=1S/C47H50FN6O10PS/c1-29(2)43(55)51-46-50-42-40(44(56)52-46)49-28-53(42)45-39(48)41(64-65-54-25-11-16-36(54)38(63-65)27-66(57,58)35-14-9-6-10-15-35)37(62-45)26-61-47(30-12-7-5-8-13-30,31-17-21-33(59-3)22-18-31)32-19-23-34(60-4)24-20-32/h5-10,12-15,17-24,28-29,36-39,41,45H,11,16,25-27H2,1-4H3,(H2,50,51,52,55,56)/t36-,37-,38+,39-,41-,45-,65+/m1/s1
DMTr-2'-F-dC(Ac)-3'-(D)-PSM-Phosphoramidite (BRP-02824) chemical structure

DMTr-2'-F-dC(Ac)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-F-dC(Ac)-3'-(D)-PSM-Phosphoramidite is a reagent used in the synthesis of oligonucleotides.
CAT: BRP-02824
Molecular Formula: C44H46FN4O10PS
Molecular Weight: 872.90
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: VMVJQKSBLJDIBX-ROFPKKATSA-N
SMILES: O=S(C[C@H]1[C@](CCC2)([H])N2[P@](O[C@H]3[C@@H](F)[C@H](N4C(N=C(NC(C)=O)C=C4)=O)O[C@@H]3COC(C5=CC=C(OC)C=C5)(C6=CC=C(OC)C=C6)C7=CC=CC=C7)O1)(C8=CC=CC=C8)=O
InChI: InChI=1S/C44H46FN4O10PS/c1-29(50)46-39-24-26-48(43(51)47-39)42-40(45)41(59-60-49-25-10-15-36(49)38(58-60)28-61(52,53)35-13-8-5-9-14-35)37(57-42)27-56-44(30-11-6-4-7-12-30,31-16-20-33(54-2)21-17-31)32-18-22-34(55-3)23-19-32/h4-9,11-14,16-24,26,36-38,40-42H,10,15,25,27-28H2,1-3H3,(H,46,47,50,51)/t36-,37-,38+,40-,41-,42-,60+/m1/s1

Frequently Asked Questions (FAQ)

What are phosphoramidites used for?

Phosphoramidites are activated monomers used in solid-phase DNA and RNA oligonucleotide synthesis.

RNA phosphoramidites include additional 2′-hydroxyl protecting groups, making them more sensitive to moisture and handling conditions.

Moisture can cause premature hydrolysis of phosphoramidites, reducing coupling efficiency and synthesis yield.

Yes, high-quality phosphoramidites are essential for achieving good yields in long and complex oligonucleotide sequences.

Modified and specialty phosphoramidites are commonly used to introduce functional groups or labels into oligonucleotides.

Frequently Asked Questions
* Only for research. Not suitable for any diagnostic or therapeutic use.

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