Nucleosides - RNA / BOC Sciences

N4-Acetyl-5'-O-DMT-2'-O-methylcytidine

Description: N4-Acetyl-5'-O-DMT-2'-O-methylcytidine, a crucial compound of immense significance in the biomedical sector, plays a pivotal role in combating viral diseases such as hepatitis C and respiratory syncytial virus (RSV) infections.

CAT: BRP-00090

CAS: 199593-08-3

MF: C33H35N3O8

MF: 601.65

Purity: ≥98% by HPLC

Appearance: White to Pale Yellow Powder

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Storage: Store at 2-8°C

Density: 1.28±0.1 g/cm3 (Predicted)

InChIKey: FINUHOJILDNELQ-PMFUCWTESA-N

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OC

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C33H35N3O8/c1-21(37)34-28-18-19-36(32(39)35-28)31-30(42-4)29(38)27(44-31)20-43-33(22-8-6-5-7-9-22,23-10-14-25(40-2)15-11-23)24-12-16-26(41-3)17-13-24/h5-19,27,29-31,38H,20H2,1-4H3,(H,34,35,37,39)/t27-,29-,30-,31-/m1/s1

Synonyms: 5'-DMT-2'-O-Methyl Cytidine (n-acetyl); 5'-DMT-2'-OMe-Ac-C; N4-Acetyl-5'-O-DMT-2'-O-methyl-D-cytidine; 5'-O-(4,4'-Dimethoxytrityl)-N4-Acetyl-2'-O-Methy-Cytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-cytidine; 5'-O-DMT-N4-Acetyl-2'-O-Methyl-cytidine; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine

N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine

Description: N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine is an astounding chemical compound allowing for the precise modulation of enzymes and receptors, used in studying cancer, viral infections and neurological disorders.

CAT: BRP-00091

CAS: 110764-72-2

MF: C39H37N5O7

MF: 687.74

Purity: ≥98% by HPLC

Appearance: White to Pale Yellow Powder

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Storage: Store at 2-8°C

Density: 1.32±0.1 g/cm3 (Predicted)

InChIKey: SARHDAQOZNKZCC-CJEGOSRCSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C39H37N5O7/c1-47-29-18-14-27(15-19-29)39(26-12-8-5-9-13-26,28-16-20-30(48-2)21-17-28)50-22-31-33(45)34(49-3)38(51-31)44-24-42-32-35(40-23-41-36(32)44)43-37(46)25-10-6-4-7-11-25/h4-21,23-24,31,33-34,38,45H,22H2,1-3H3,(H,40,41,43,46)/t31-,33-,34-,38-/m1/s1

Synonyms: 5'-DMT-2'-(O-Methyl) Adenosine (n-bz); 5'-DMT-2'-OMe-Bz-A; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-O-methyladenosine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)-phenylmethyl]-2'-O-methyl-adenosine; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine

5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine

Description: 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine, a remarkable antiviral agent employed in advanced biomedical investigations, defies viral replication across diverse strains, such as the treacherous influenza and herpes simplex virus. Equally significant, this compound boasts unrivaled eminence in probing RNA biology and delineating protein synthesis intricacies. Scientific affluence beckons its application, impelling groundbreaking inquiries exploring viral replication mechanisms and pioneering antiviral therapies.

CAT: BRP-00092

CAS: 114745-26-5

MF: C36H39N5O8

MF: 669.74

Purity: ≥98% by HPLC

Appearance: White to light yellow powder

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Storage: Store at -20 °C

Density: 1.35±0.1 g/cm3(Predicted)

InChIKey: ISQLJOGRNUQHJX-WIFIACMTSA-N

Solubility: Soluble in acetonitrile

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C36H39N5O8/c1-21(2)32(43)39-35-38-31-28(33(44)40-35)37-20-41(31)34-30(47-5)29(42)27(49-34)19-48-36(22-9-7-6-8-10-22,23-11-15-25(45-3)16-12-23)24-13-17-26(46-4)18-14-24/h6-18,20-21,27,29-30,34,42H,19H2,1-5H3,(H2,38,39,40,43,44)/t27-,29-,30-,34-/m1/s1

Synonyms: N2-iBu-2'-OMe-5'-O-DMT-G; N2-iBu-2'-OMe-5'-O-DMT-G; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)guanosine; 5'-DMT-2'-(O-Methyl) Guanosine (n-ibu)

5'-O-DMT-2'-O-methyluridine

Description: It is used for RNA synthesis and nucleoside modification.

CAT: BRP-00093

CAS: 103285-22-9

MF: C31H32N2O8

MF: 560.59

Purity: ≥98% by HPLC

Appearance: White to light yellow powder

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Storage: Store at 2-8 °C

Density: 1.35±0.1 g/cm³(Predicted)

InChIKey: MFDHAVFJDSRPKC-YXINZVNLSA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O

IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C31H32N2O8/c1-37-23-13-9-21(10-14-23)31(20-7-5-4-6-8-20,22-11-15-24(38-2)16-12-22)40-19-25-27(35)28(39-3)29(41-25)33-18-17-26(34)32-30(33)36/h4-18,25,27-29,35H,19H2,1-3H3,(H,32,34,36)/t25-,27-,28-,29-/m1/s1

Synonyms: 5'-DMT-2'-(O-Methyl) Uridine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-Methyluridine; 5'-O-DMT-2'-O-methyl-D-uridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyluridine

N-Isobutyrylguanosine

Description: N-Isobutyrylguanosine is used in the syntehsis of 2'-O-(o-nitrobenzyl)-3'-thioguanosine phosphoramidite which is then used to form oligonucleotides, substrates for probing the mechanism of RNA catalysis.

CAT: BRP-00103

CAS: 64350-24-9

MF: C14H19N5O6

MF: 353.33

Purity: ≥95%

Appearance: White to off-white solid

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Storage: Store at -20 °C under inert atmosphere

Density: 1.82±0.1 g/cm³ (Predicted)

Melting Point: >160 °C (dec.)

InChIKey: OXTYJSXVUGJSGM-HTVVRFAVSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C14H19N5O6/c1-5(2)11(23)17-14-16-10-7(12(24)18-14)15-4-19(10)13-9(22)8(21)6(3-20)25-13/h4-6,8-9,13,20-22H,3H2,1-2H3,(H2,16,17,18,23,24)/t6-,8-,9-,13-/m1/s1

Synonyms: N2-iso-Butyrylguanosine; N2-Isobutyrylguanosine; N-(2-methylpropanoyl)guanosine; N-(2-Methyl-1-oxopropyl)guanosine; N-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-methylpropanamide; ribo Guanosine (n-ibu)

N6-Benzoyladenosine

Description: It's an anti-tumor drug.

CAT: BRP-00104

CAS: 4546-55-8

MF: C17H17N5O5

MF: 371.35

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at 2-8°C

Density: 1.708 g/cm3

Melting Point: 141-145°C

InChIKey: NZDWTKFDAUOODA-CNEMSGBDSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: C1=CC=C(C=C1)C(=O)NC2=NC=NC3=C2N=CN3C4C(C(C(O4)CO)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C17H17N5O5/c23-6-10-12(24)13(25)17(27-10)22-8-20-11-14(18-7-19-15(11)22)21-16(26)9-4-2-1-3-5-9/h1-5,7-8,10,12-13,17,23-25H,6H2,(H,18,19,21,26)/t10-,12-,13-,17-/m1/s1

Synonyms: N6-benzoyl-adenosine; N-Benzoyladenosine; N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; Benzamide, N-(9-beta-D-ribofuranosyl-9H-purin-6-yl)-; ribo Adenosine (n-bz); rA(Bz)

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-adenosine

Description: N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-adenosine is a commonly used reactant in the preparation of nucleosidic phosphoramidite derivatives.

CAT: BRP-00105

CAS: 251647-48-0

MF: C41H41N5O8

MF: 731.79

Purity: ≥95%

Appearance: Off-white to Pale Yellow Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.31±0.1 g/cm3

Melting Point: 95-98°C

InChIKey: KEVMXGNDTKPSMC-MUMPVVMASA-N

Solubility: Soluble in Acetonitrile (Sparingly), Chloroform (Slightly), DMF (Slightly, Sonicated), DMSO

CanonicalSMILES: COCCOC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C41H41N5O8/c1-49-22-23-52-36-35(47)33(54-40(36)46-26-44-34-37(42-25-43-38(34)46)45-39(48)27-10-6-4-7-11-27)24-53-41(28-12-8-5-9-13-28,29-14-18-31(50-2)19-15-29)30-16-20-32(51-3)21-17-30/h4-21,25-26,33,35-36,40,47H,22-24H2,1-3H3,(H,42,43,45,48)/t33-,35-,36-,40-/m1/s1

Synonyms: N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosine; N-(9-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-adenosine; 2'-O-MOE-5'-O-DMT-A(Bz); 5'-O-DMT-2'-O-MOE-N6-Bz-rA

5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine

Description: 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine, an intriguing bioactive compound, has garnered attention in the biomedical industry for its potential antiviral prowess. Demonstrating commendable efficacy in impeding viral replication, it holds promise in combatting viral ailments such as herpes and hepatitis. However, the precise workings of this compound remain enigmatic, warranting further exploration in the realm of antiviral drug development.

CAT: BRP-00106

CAS: 251647-50-4

MF: C38H43N5O9

MF: 713.78

Purity: ≥95%

Appearance: White to Pale Yellow Crystalline Powder

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Storage: Store at RT

Density: 1.33±0.1 g/cm3(Predicted)

Melting Point: 112.5-126.6 °C

InChIKey: XDLPRZLZAFJSMA-BEGXHNNXSA-N

Solubility: Soluble in Hexane

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OCCOC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C38H43N5O9/c1-23(2)34(45)41-37-40-33-30(35(46)42-37)39-22-43(33)36-32(50-20-19-47-3)31(44)29(52-36)21-51-38(24-9-7-6-8-10-24,25-11-15-27(48-4)16-12-25)26-13-17-28(49-5)18-14-26/h6-18,22-23,29,31-32,36,44H,19-21H2,1-5H3,(H2,40,41,42,45,46)/t29-,31-,32-,36-/m1/s1

Synonyms: N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 2'-O-MOE-5'-O-DMT-G(iBu); 5'-O-DMT-2'-O-MOE-N2-iBu-rG; 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine

2'-O-(2-Methoxyethyl)-5-methylcytidine

Description: 2'-O-(2-Methoxyethyl)-5-methylcytidine is an intrinsic antiviral compound, garnering substantial interest within the biomedical field for the research of its efficacy against RNA viruses. By impeding viral replication, this compound presenting a formidable prospect for the formulation of unprecedented antiviral interventions.

CAT: BRP-00107

CAS: 244105-55-3

MF: C13H21N3O6

MF: 315.32

Purity: ≥98% by HPLC

Appearance: White to off-white crystalline powder

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Storage: Store at -20°C under inert atmosphere

Density: 1.52 g/cm3

Melting Point: >70°C (dec.)

Boiling Point: 536.5±60.0 °C(Predicted)

InChIKey: GUEIFVRYWPOXHJ-DNRKLUKYSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)OCCOC

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidin-2-one

InChI: InChI=1S/C13H21N3O6/c1-7-5-16(13(19)15-11(7)14)12-10(21-4-3-20-2)9(18)8(6-17)22-12/h5,8-10,12,17-18H,3-4,6H2,1-2H3,(H2,14,15,19)/t8-,9-,10-,12-/m1/s1

Synonyms: 5-Me-2'-O-MOE-C; 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one; 5-Methyl-2'-O-methoxyethyl-cytidine; 5-Me-2'-O-MOE-Cr

N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine

Description: N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine, a potent biomedicine, holds significant promise as an antiviral therapeutic agent.

CAT: BRP-00108

CAS: 182496-01-1

MF: C41H43N3O9

MF: 721.79

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at -20°C

Density: 1.26±0.1 g/cm3

InChIKey: BYSCLUAIKFEFAH-LZURGKRNSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OCCOC

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C41H43N3O9/c1-27-25-44(40(47)43-37(27)42-38(46)28-11-7-5-8-12-28)39-36(51-24-23-48-2)35(45)34(53-39)26-52-41(29-13-9-6-10-14-29,30-15-19-32(49-3)20-16-30)31-17-21-33(50-4)22-18-31/h5-22,25,34-36,39,45H,23-24,26H2,1-4H3,(H,42,43,46,47)/t34-,35-,36-,39-/m1/s1

Synonyms: N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-(2-methoxyethyl)-5-methylcytidine; N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine; N4-Benzoyl-2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine; 2'-O-MOE-5'-O-DMT-5-Me-C(Bz); 5'-O-DMT-2'-O-MOE-5-Me-C(Bz)

2'-O-(2-Methoxyethy)-5-methyluridine

Description: 2'-O-(2-Methoxyethy)-5-methyluridine is a nucleoside analog renowned in the biomedical realm, unveiling its potent antiviral attributes. I

CAT: BRP-00109

CAS: 163759-49-7

MF: C13H20N2O7

MF: 316.31

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

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Storage: Store at -20°C under inert atmosphere

Density: 1.41 g/cm3

Melting Point: 115.5-116.5 °C

InChIKey: NEVQCHBUJFYGQO-DNRKLUKYSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)OCCOC

IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C13H20N2O7/c1-7-5-15(13(19)14-11(7)18)12-10(21-4-3-20-2)9(17)8(6-16)22-12/h5,8-10,12,16-17H,3-4,6H2,1-2H3,(H,14,18,19)/t8-,9-,10-,12-/m1/s1

Synonyms: 2'-O-MOE-5-Methyluridine; 2'-O-Methoxyethyl-thymidine; 2'-O-MOE-T; 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5-Me-2'-O-MOE U; 5-Me-2'-O-MOE Uridine

5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine

Description: 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a potent compound used in research of RNA viruses, particularly hepatitis C virus and picornaviruses. This nucleoside analogue inhibits viral replication by interfering with viral RNA research and development.

CAT: BRP-00110

CAS: 163759-50-0

MF: C34H38N2O9

MF: 618.67

Purity: ≥98% by HPLC

Appearance: Off-white Crystalline Powder

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Storage: Store at RT

Density: 1.32 g/cm3

InChIKey: WIPCVBQXKBWNRC-PBAMLIMUSA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OCCOC

IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C34H38N2O9/c1-22-20-36(33(39)35-31(22)38)32-30(43-19-18-40-2)29(37)28(45-32)21-44-34(23-8-6-5-7-9-23,24-10-14-26(41-3)15-11-24)25-12-16-27(42-4)17-13-25/h5-17,20,28-30,32,37H,18-19,21H2,1-4H3,(H,35,38,39)/t28-,29-,30-,32-/m1/s1

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine; 5'-O-DMT-2'-O-MOE-5-methyluridine; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyluridine; 5'-O-DMT-2'-O-MOE-5-MeU

2,2'-Anhydrouridine

Description: 2,2'-Anhydrouridine is a modified nucleoside that lacks a hydroxyl group at the 2' position of the ribose ring. It is commonly found in transfer RNA (tRNA) and plays a role in stabilizing the tRNA structure. This modification is important for proper tRNA function as it helps maintain the overall stability and folding of the molecule. 2,2'-Anhydrouridine is also known to be involved in the recognition and binding of tRNA to the ribosome during protein synthesis.

CAT: BRP-00111

CAS: 3736-77-4

MF: C9H10N2O5

MF: 226.19

Purity: ≥95%

Appearance: White to off-white (Solid)

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Storage: Store at RT

Density: 2.01±0.1 g/cm3

Melting Point: 234-235 °C

Boiling Point: 456.3±55.0 °C at 760 mmHg

Flash Point: 229.8±31.5 °C

InChIKey: UUGITDASWNOAGG-CCXZUQQUSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=O

IUPAC Name: (2R,4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one

InChI: InChI=1S/C9H10N2O5/c12-3-4-6(14)7-8(15-4)11-2-1-5(13)10-9(11)16-7/h1-2,4,6-8,12,14H,3H2/t4-,6-,7+,8-/m1/s1

Synonyms: 2,2'-Anhydro-b-D-arabinofuranosyl uracil; O-2,2'-Cyclouridine; 2,2'-Anhydro-D-uridine; 2,2'-Anhydro Uridine; (2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-2-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-on; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, [2R-(2α,3β,3aβ,9aβ)]-; 2,2'-Anhydro(1-β-D-arabinofuranosyl)uracil; 2,2'-Anhydro-N1-(β-D-arabinofuranosyl)uracil; 2,2'-Anhydrouridine; 2,2'-O-Cyclouridine; NSC 157148; O2,2'-Anhydrouridine; O2,2'-Cyclouridine; β-D-2',2-O-Cycloarabinouridine

2,2'-Anhydro-5-methyluridine

Description: 2,2'-Anhydro-5-methyluridine is a chemically modified nucleoside derivative of uridine, where the 2' hydroxyl group of the ribose is linked to the 2-position of the uracil ring, forming an anhydro bond. Additionally, the uracil base is methylated at the 5-position. This modification alters the nucleoside's properties, making it useful in biochemical and pharmacological research, particularly in studies focused on nucleic acid chemistry and potential therapeutic applications.

CAT: BRP-00112

CAS: 22423-26-3

MF: C10H12N2O5

MF: 240.21

Purity: ≥95%

Appearance: White to off-white crystalline powder

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Storage: Store at RT

Density: 1.88±0.1 g/cm³ (Predicted)

Melting Point: 217.0-221.0 °C

Boiling Point: 452.0±55.0 °C (Predicted)

InChIKey: WLLOAUCNUMYOQI-JAGXHNFQSA-N

CanonicalSMILES: CC1=CN2C3C(C(C(O3)CO)O)OC2=NC1=O

IUPAC Name: (2R,4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one

InChI: InChI=1S/C10H12N2O5/c1-4-2-12-9-7(6(14)5(3-13)16-9)17-10(12)11-8(4)15/h2,5-7,9,13-14H,3H2,1H3/t5-,6-,7+,9-/m1/s1

Synonyms: O-2,2'-Anhydro-5-methyluridine; 2,2'-Anhydro-5-methyl-D-uridine; 2,2'-Anhydro-(1-b-D-arabinofuranosyl)-5-methyluracil; 2,2'-Anhydro-D-thymidine; 2,2'-Anhydro-5-methyluridine; (2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one; 2,2'-Anhydro-1-beta-arabinofuranosylthymine

5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine

Description: 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is an exceptionally powerful antiviral compound, possessing an unparalleled propensity to combat the scourges perpetuated by viral entities. It acts as a formidable weapon against the replication machineries employed by diverse RNA viruses, such as influenza, hepatitis C and respiratory syncytial virus (RSV).

CAT: BRP-00114

CAS: 182496-00-0

MF: C34H39N3O8

MF: 617.69

Purity: ≥95% by HPLC

Appearance: White to Off-white Solid

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Storage: Store at 2-8 °C

Density: 1.27±0.1 g/cm3 (Predicted)

Boiling Point: 762.6±70.0 °C at 760 mmHg

InChIKey: LYKTVJJXZQTNPK-PBAMLIMUSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OCCOC

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidin-2-one

InChI: InChI=1S/C34H39N3O8/c1-22-20-37(33(39)36-31(22)35)32-30(43-19-18-40-2)29(38)28(45-32)21-44-34(23-8-6-5-7-9-23,24-10-14-26(41-3)15-11-24)25-12-16-27(42-4)17-13-25/h5-17,20,28-30,32,38H,18-19,21H2,1-4H3,(H2,35,36,39)/t28-,29-,30-,32-/m1/s1

Synonyms: 4-Amino-1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one; 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine; 2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine; 2'-O-MOE-5'-O-DMT-5-Me-C; 5'-O-DMT-2'-O-MOE-5-MeC

2,2'-Anhydro-5'-O-DMT-5-methyluridine

Description: 2,2'-Anhydro-5'-O-DMT-5-methyluridine is a remarkable biomedicine agent having shown substantial efficacy in research of combating viral infections and specific neoplastic conditions. Unveiling its antiviral prowess against RNA viruses, this compound showcases a promising proclivity for impeding malignant tumor expansion.

CAT: BRP-00115

CAS: 817623-11-3

MF: C31H30N2O7

MF: 542.58

Purity: ≥95%

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Storage: Store at 2-8 °C

Density: 1.3±0.1 g/cm3

Boiling Point: 692.9±65.0°C at 760 mmHg

InChIKey: BQEQCEZNLIKSSH-CITHKVLSSA-N

CanonicalSMILES: CC1=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OC2=NC1=O

IUPAC Name: (2R,4R,5R,6S)-4-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-hydroxy-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one

InChI: InChI=1S/C31H30N2O7/c1-19-17-33-29-27(40-30(33)32-28(19)35)26(34)25(39-29)18-38-31(20-7-5-4-6-8-20,21-9-13-23(36-2)14-10-21)22-11-15-24(37-3)16-12-22/h4-17,25-27,29,34H,18H2,1-3H3/t25-,26-,27+,29-/m1/s1

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-5-methyl-2,2'-anhydro-b-D-arabinofuranosyluracil; 5'-O-(4,4'-Dimethoxytrityl)-5-methyl-2,2'-anhydro-D-uridine; 5'-DMTr-2,2'-anhydrothymidine; (2R,3R,3aS,9aR)-2-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-hydroxy-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one

5'-O-(4,4'-Dimethoxytrityl)-2,2'-anhydro-D-uridine

Description: 5'-O-(4,4'-Dimethoxytrityl)-2,2'-anhydro-D-uridine, a multifaceted compound extensively employed in the field of biomedicine, exhibits utmost significance. Its pivotal involvement lies within the synthesis of pharmaceutical nucleoside analogs, specifically for combating viral infections such as HIV and hepatitis.

CAT: BRP-00116

CAS: 173170-12-2

MF: C30H28N2O7

MF: 528.55

Purity: ≥95%

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Density: 1.4±0.1 g/cm3

Boiling Point: 688.2±65.0°C at 760 mmHg

InChIKey: OEIRLWHCGAICDW-AOGFTHLWSA-N

CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C5C(O4)N6C=CC(=O)N=C6O5)O

IUPAC Name: (2R,4R,5R,6S)-4-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-hydroxy-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one

InChI: InChI=1S/C30H28N2O7/c1-35-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(36-2)15-11-21)37-18-24-26(34)27-28(38-24)32-17-16-25(33)31-29(32)39-27/h3-17,24,26-28,34H,18H2,1-2H3/t24-,26-,27+,28-/m1/s1

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2,2'-anhydro-b-D-arabinofuranosyluracil; (2R,3R,3aS,9aR)-2-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-hydroxy-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one; 2,2'-Anhydro-5'-O-DMT-uridine; 2,2'-Anhydro-5'-O-(4,4'-dimethoxytrityl)uridine; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-2,3,3a,9a-tetrahydro-3-hydroxy-, [2R-(2α,3β,3aβ,9aβ)]-

S-Adenosyl-L-Methionine

Description: S-adenosyl-l-methionine (SAMe) is a naturally occurring substance which is a major source of methyl groups in the brain. The efficacy of SAMe in treating depressive syndromes and disorders is superior to that of placebo and comparable to that of standard tricyclic antidepressants. Since SAMe is a naturally occurring compound with relatively few side effects, it is a potentially important treatment for depression. S-adenosylmethionine (SAMe) is a dietary supplement used in the management of osteoarthritis (OA) symptoms. Studies evaluating SAMe in the management of OA have been limited to Non Steroidal Anti-inflammatory Drugs (NSAIDs) for comparison. The present study compares the effectiveness of SAMe to a cyclooxygenase-2 (COX-2) inhibitor (celecoxib) for pain control, functional improvement and to decrease side effects in people with osteoarthritis of the knee. It also acts as a PDE4B inhibitor.
Nutritional supplement in health care products.

CAT: BRP-00119

CAS: 29908-03-0

MF: C15H22N6O5S

MF: 398.44

Purity: 98%

Appearance: White to Off-White Powder

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Storage: Store at -20 °C

Application: Ingredient of health care products.

InChIKey: MEFKEPWMEQBLKI-AIRLBKTGSA-N

CanonicalSMILES: C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O

IUPAC Name: (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate

InChI: InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/t7-,8+,10+,11+,14+,27?/m0/s1

Synonyms: S-Adenosylmethionine; Ademetionine; AdoMet; MSI-195; MSI 195; MSI195; SAMe; S-Adenosyl-L-methionine; L-S-Adenosylmethionine; S-Adenosyl methionine; Adenosine, 5'-[(L-3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxy-, hydroxide, inner salt; Active methionine; Adenosyl-L-methionine; Donamet; S Amet; SAH (S-Adenosylmethionine); SAM; SAM (S-Adenosyl methionine); Transmetil

5-Fluoro Cytidine

Description: 5-Fluoro Cytidine is a modified nucleoside that contains a fluorine atom at the 5th position of the cytidine molecule. It is a synthetic compound that has shown potential therapeutic effects in the treatment of certain types of cancer. 5-Fluoro Cytidine works by disrupting the process of RNA replication and inhibiting cell growth. It is currently being studied in clinical trials for its anti-cancer properties. 5-Fluoropyrimidine nucleotides as RNA structure probe using 19F-NMR spectroscopy.

CAT: BRP-00127

CAS: 2341-22-2

MF: C9H12FN3O5

MF: 261.21

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20°C

Density: 1.98±0.1 g/cm3 (Predicted)

Melting Point: 183-185°C

Boiling Point: 511.4±60.0°C (Predicted)

InChIKey: STRZQWQNZQMHQR-UAKXSSHOSA-N

Solubility: Soluble in Methanol (Slightly, Heated), Water (Slightly)

CanonicalSMILES: C1=C(C(=NC(=O)N1C2C(C(C(O2)CO)O)O)N)F

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidin-2-one

InChI: InChI=1S/C9H12FN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1

Synonyms: 5-Fluorocytidine; 5F-C; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one; 4-Amino-5-fluor-1-(β-D-ribofuranosyl)pyrimidin-2(1H)-one; L-β-Ribofuranosyl-5-fluoro-cytosine

3-Deazaadenosine

Description: 3-Deazaadenosine (3-DZA) is an inhibitor of SAH hydrolase (Ki = 3.9 μM). 3-Deazaadenosine is a modified form of the nucleoside adenosine, where a nitrogen atom in the purine ring is replaced with a carbon atom. This modification results in the compound lacking the ability to form hydrogen bonds with complementary nucleotides, making it useful in studying the role of hydrogen bonding in nucleic acid structure and function. 3-Deazaadenosine has been investigated for its potential therapeutic applications, such as in the treatment of viral infections and cancer. It is also used as a biochemical tool in research to study RNA interactions and enzymatic mechanisms.

CAT: BRP-00145

CAS: 6736-58-9

MF: C11H14N4O4

MF: 266.26

Purity: ≥97% by HPLC

Appearance: Crystalline Solid

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Storage: Store at -20°C

Density: 1.90±0.1 g/cm3 at 20°C, 760 Torr

Melting Point: 222-224°C

Boiling Point: 665.7±65.0°C (Predicted)

Flash Point: 356.4±34.3 °C

InChIKey: DBZQFUNLCALWDY-PNHWDRBUSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN=C(C2=C1N(C=N2)C3C(C(C(O3)CO)O)O)N

IUPAC Name: (2R,3R,4S,5R)-2-(4-aminoimidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C11H14N4O4/c12-10-7-5(1-2-13-10)15(4-14-7)11-9(18)8(17)6(3-16)19-11/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13)/t6-,8-,9-,11-/m1/s1

Synonyms: Deaza-Ado; (2R,3R,4S,5R)-2-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 3-Deaza-rA; 1-(beta-D-ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine; 4-Amino-1-(β-D-ribofuranosyl)-1H-imidazo(4,5)-pyridine