Nucleosides

2'-Modified Nucleosides
(303/303)
3'-Modified Nucleosides
(173/173)
5'-Modified Nucleosides
(252/252)
Anhydro-Nucleosides
(13/13)
Arabinonucleosides
(34/34)
Base Protected Nucleosides
(234/234)
Halogen Nucleosides
(134/134)
L-Nucleosides
(18/18)
Other Nucleosides
(77/77)
Other Protected Nucleosides
(23/23)
Ribonucleosides
(11/11)
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2'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N4-acetylcytidine

Description: It is used for nucleoside modification and nucleic acid synthesis.
CAT: BRP-00086
CAS: 121058-85-3
Molecular Formula: C38H47N3O8Si
Molecular Weight: 701.88
Purity: ≥95%
Appearance: White to Off-white Crystalline Powder
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Storage: Store at 2-8°C
Density: 1.19±0.1 g/cm3 (Predicted)
InChIKey: ZFRWPAYPCFTQHK-HYGOWAQNSA-N
CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)O[Si](C)(C)C(C)(C)C
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C38H47N3O8Si/c1-25(42)39-32-22-23-41(36(44)40-32)35-34(49-50(7,8)37(2,3)4)33(43)31(48-35)24-47-38(26-12-10-9-11-13-26,27-14-18-29(45-5)19-15-27)28-16-20-30(46-6)21-17-28/h9-23,31,33-35,43H,24H2,1-8H3,(H,39,40,42,44)/t31-,33-,34-,35-/m1/s1
Synonyms: 2'-O-TBDMS-5'-O-DMT-N4-Ac cytidine; N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine; N4-acetyl-2'-O-(t-butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)cytidine; 5'-O-(4,4'-Dimethoxytrityl) 2'-O-[(1,1-dimethylethyl)-dimethylsilyl]-N4-acetylcytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine; N4-Ac-2'-O-TBDMS-5'-O-DMT-C; N4-Ac-DMT-2'-O-TBDMS-Cr; N4-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-cytidine; 5'-DMT-2'-tBDSilyl Cytidine (n-acetyl)

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine

Description: 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine, an indispensable compound utilized in the biomedical sector, showcases immense promise in combatting a plethora of diseases and disorders, namely cancer and viral infections. Its extraordinary configuration empowers it to disrupt replication procedures, rendering it a highly efficacious agent against antiviral and anticancer fronts.
CAT: BRP-00087
CAS: 81279-39-2
Molecular Formula: C41H51N5O8Si
Molecular Weight: 769.96
Purity: ≥95%
Appearance: White powder
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Storage: Store at -20 °C
Density: 1.3±0.1 g/cm3
InChIKey: JMCNKJFOIJGYRG-CJEGOSRCSA-N
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)O[Si](C)(C)C(C)(C)C
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C41H51N5O8Si/c1-25(2)36(48)44-39-43-35-32(37(49)45-39)42-24-46(35)38-34(54-55(8,9)40(3,4)5)33(47)31(53-38)23-52-41(26-13-11-10-12-14-26,27-15-19-29(50-6)20-16-27)28-17-21-30(51-7)22-18-28/h10-22,24-25,31,33-34,38,47H,23H2,1-9H3,(H2,43,44,45,48,49)/t31-,33-,34-,38-/m1/s1
Synonyms: N2-iBu-2'-O-TBDMS-5'-O-DMT-G; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine; N2-iBu-DMT-2'-O-TBDMS-Gr; N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-guanosine; 5'-DMT-2'-tBDSilyl Guanosine (n-ibu)

2'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N6-benzoyladenosine

Description: It is a fluorescent adenosine-containing compound commonly used to detect DNA/RNA modifications or to add synthetic oligonucleotide blocks.
CAT: BRP-00088
CAS: 81265-93-2
Molecular Formula: C44H49N5O7Si
Molecular Weight: 787.97
Purity: ≥95%
Appearance: White to Off-white Crystalline Powder
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Storage: Store at -20°C
Density: 1.23±0.1 g/cm3 (Predicted)
InChIKey: DAZIGOPASNJPCJ-GNECSJIWSA-N
CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C44H49N5O7Si/c1-43(2,3)57(6,7)56-38-37(50)35(55-42(38)49-28-47-36-39(45-27-46-40(36)49)48-41(51)29-14-10-8-11-15-29)26-54-44(30-16-12-9-13-17-30,31-18-22-33(52-4)23-19-31)32-20-24-34(53-5)25-21-32/h8-25,27-28,35,37-38,42,50H,26H2,1-7H3,(H,45,46,48,51)/t35-,37-,38-,42-/m1/s1
Synonyms: 5'-DMT-2'-tBDSilyl Adenosine (n-bz); 2'-O-TBDMS-5'-O-DMT-N6-Bz adenosine; N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine; 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)adenosine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-N-benzoyladenosine

2'-O-Tert-butyldimethylsilyl-5'-O-DMT-uridine

Description: It is used for RNA synthesis and special nucleoside modification.
CAT: BRP-00089
CAS: 81246-80-2
Molecular Formula: C36H44N2O8Si
Molecular Weight: 660.83
Purity: ≥95%
Appearance: White Solid
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Storage: Store at 2-8°C
Density: 1.3±0.1 g/cm3
InChIKey: KVHQIELPHWJPSY-WXQJYUTRSA-N
CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O
IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C36H44N2O8Si/c1-35(2,3)47(6,7)46-32-31(40)29(45-33(32)38-22-21-30(39)37-34(38)41)23-44-36(24-11-9-8-10-12-24,25-13-17-27(42-4)18-14-25)26-15-19-28(43-5)20-16-26/h8-22,29,31-33,40H,23H2,1-7H3,(H,37,39,41)/t29-,31-,32-,33-/m1/s1
Synonyms: 5'-DMT-2'-tBDSilyl Uridine; 5'-O-DMT-2'-O-TBDMS uridine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-t-butyldimethylsilyl uridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)uridine; 5'-O-(4,4'-Dimethoxytrityl) 2'-O-[(1,1-dimethylethyl)-dimethylsilyl]-uridine

N4-Acetyl-5'-O-DMT-2'-O-methylcytidine

Description: N4-Acetyl-5'-O-DMT-2'-O-methylcytidine, a crucial compound of immense significance in the biomedical sector, plays a pivotal role in combating viral diseases such as hepatitis C and respiratory syncytial virus (RSV) infections.
CAT: BRP-00090
CAS: 199593-08-3
Molecular Formula: C33H35N3O8
Molecular Weight: 601.65
Purity: ≥98% by HPLC
Appearance: White to Pale Yellow Powder
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Storage: Store at 2-8°C
Density: 1.28±0.1 g/cm3 (Predicted)
InChIKey: FINUHOJILDNELQ-PMFUCWTESA-N
CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OC
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C33H35N3O8/c1-21(37)34-28-18-19-36(32(39)35-28)31-30(42-4)29(38)27(44-31)20-43-33(22-8-6-5-7-9-22,23-10-14-25(40-2)15-11-23)24-12-16-26(41-3)17-13-24/h5-19,27,29-31,38H,20H2,1-4H3,(H,34,35,37,39)/t27-,29-,30-,31-/m1/s1
Synonyms: 5'-DMT-2'-O-Methyl Cytidine (n-acetyl); 5'-DMT-2'-OMe-Ac-C; N4-Acetyl-5'-O-DMT-2'-O-methyl-D-cytidine; 5'-O-(4,4'-Dimethoxytrityl)-N4-Acetyl-2'-O-Methy-Cytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-cytidine; 5'-O-DMT-N4-Acetyl-2'-O-Methyl-cytidine; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine

N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine

Description: N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine is an astounding chemical compound allowing for the precise modulation of enzymes and receptors, used in studying cancer, viral infections and neurological disorders.
CAT: BRP-00091
CAS: 110764-72-2
Molecular Formula: C39H37N5O7
Molecular Weight: 687.74
Purity: ≥98% by HPLC
Appearance: White to Pale Yellow Powder
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Storage: Store at 2-8°C
Density: 1.32±0.1 g/cm3 (Predicted)
InChIKey: SARHDAQOZNKZCC-CJEGOSRCSA-N
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C39H37N5O7/c1-47-29-18-14-27(15-19-29)39(26-12-8-5-9-13-26,28-16-20-30(48-2)21-17-28)50-22-31-33(45)34(49-3)38(51-31)44-24-42-32-35(40-23-41-36(32)44)43-37(46)25-10-6-4-7-11-25/h4-21,23-24,31,33-34,38,45H,22H2,1-3H3,(H,40,41,43,46)/t31-,33-,34-,38-/m1/s1
Synonyms: 5'-DMT-2'-(O-Methyl) Adenosine (n-bz); 5'-DMT-2'-OMe-Bz-A; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-O-methyladenosine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)-phenylmethyl]-2'-O-methyl-adenosine; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine

5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine

Description: 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine, a remarkable antiviral agent employed in advanced biomedical investigations, defies viral replication across diverse strains, such as the treacherous influenza and herpes simplex virus. Equally significant, this compound boasts unrivaled eminence in probing RNA biology and delineating protein synthesis intricacies. Scientific affluence beckons its application, impelling groundbreaking inquiries exploring viral replication mechanisms and pioneering antiviral therapies.
CAT: BRP-00092
CAS: 114745-26-5
Molecular Formula: C36H39N5O8
Molecular Weight: 669.74
Purity: ≥98% by HPLC
Appearance: White to light yellow powder
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Storage: Store at -20 °C
Density: 1.35±0.1 g/cm3(Predicted)
InChIKey: ISQLJOGRNUQHJX-WIFIACMTSA-N
Solubility: Soluble in acetonitrile
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C36H39N5O8/c1-21(2)32(43)39-35-38-31-28(33(44)40-35)37-20-41(31)34-30(47-5)29(42)27(49-34)19-48-36(22-9-7-6-8-10-22,23-11-15-25(45-3)16-12-23)24-13-17-26(46-4)18-14-24/h6-18,20-21,27,29-30,34,42H,19H2,1-5H3,(H2,38,39,40,43,44)/t27-,29-,30-,34-/m1/s1
Synonyms: N2-iBu-2'-OMe-5'-O-DMT-G; N2-iBu-2'-OMe-5'-O-DMT-G; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)guanosine; 5'-DMT-2'-(O-Methyl) Guanosine (n-ibu)

5'-O-DMT-2'-O-methyluridine

Description: It is used for RNA synthesis and nucleoside modification.
CAT: BRP-00093
CAS: 103285-22-9
Molecular Formula: C31H32N2O8
Molecular Weight: 560.59
Purity: ≥98% by HPLC
Appearance: White to light yellow powder
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Storage: Store at 2-8 °C
Density: 1.35±0.1 g/cm3(Predicted)
InChIKey: MFDHAVFJDSRPKC-YXINZVNLSA-N
CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O
IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C31H32N2O8/c1-37-23-13-9-21(10-14-23)31(20-7-5-4-6-8-20,22-11-15-24(38-2)16-12-22)40-19-25-27(35)28(39-3)29(41-25)33-18-17-26(34)32-30(33)36/h4-18,25,27-29,35H,19H2,1-3H3,(H,32,34,36)/t25-,27-,28-,29-/m1/s1
Synonyms: 5'-DMT-2'-(O-Methyl) Uridine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-Methyluridine; 5'-O-DMT-2'-O-methyl-D-uridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyluridine

N-Isobutyrylguanosine

Description: N-Isobutyrylguanosine is used in the syntehsis of 2'-O-(o-nitrobenzyl)-3'-thioguanosine phosphoramidite which is then used to form oligonucleotides, substrates for probing the mechanism of RNA catalysis.
CAT: BRP-00103
CAS: 64350-24-9
Molecular Formula: C14H19N5O6
Molecular Weight: 353.33
Purity: ≥95%
Appearance: White to off-white solid
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Storage: Store at -20 °C under inert atmosphere
Density: 1.82±0.1 g/cm3 (Predicted)
Melting Point: >160 °C (dec.)
InChIKey: OXTYJSXVUGJSGM-HTVVRFAVSA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)O
IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C14H19N5O6/c1-5(2)11(23)17-14-16-10-7(12(24)18-14)15-4-19(10)13-9(22)8(21)6(3-20)25-13/h4-6,8-9,13,20-22H,3H2,1-2H3,(H2,16,17,18,23,24)/t6-,8-,9-,13-/m1/s1
Synonyms: N2-iso-Butyrylguanosine; N2-Isobutyrylguanosine; N-(2-methylpropanoyl)guanosine; N-(2-Methyl-1-oxopropyl)guanosine; N-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-methylpropanamide; ribo Guanosine (n-ibu)

N6-Benzoyladenosine

Description: It's an anti-tumor drug.
CAT: BRP-00104
CAS: 4546-55-8
Molecular Formula: C17H17N5O5
Molecular Weight: 371.35
Purity: ≥95%
Appearance: White to Off-white Solid
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Storage: Store at 2-8°C
Density: 1.708 g/cm3
Melting Point: 141-145°C
InChIKey: NZDWTKFDAUOODA-CNEMSGBDSA-N
Solubility: Soluble in DMSO
CanonicalSMILES: C1=CC=C(C=C1)C(=O)NC2=NC=NC3=C2N=CN3C4C(C(C(O4)CO)O)O
IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C17H17N5O5/c23-6-10-12(24)13(25)17(27-10)22-8-20-11-14(18-7-19-15(11)22)21-16(26)9-4-2-1-3-5-9/h1-5,7-8,10,12-13,17,23-25H,6H2,(H,18,19,21,26)/t10-,12-,13-,17-/m1/s1
Synonyms: N6-benzoyl-adenosine; N-Benzoyladenosine; N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; Benzamide, N-(9-beta-D-ribofuranosyl-9H-purin-6-yl)-; ribo Adenosine (n-bz); rA(Bz)

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-adenosine

Description: N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-adenosine is a commonly used reactant in the preparation of nucleosidic phosphoramidite derivatives.
CAT: BRP-00105
CAS: 251647-48-0
Molecular Formula: C41H41N5O8
Molecular Weight: 731.79
Purity: ≥95%
Appearance: Off-white to Pale Yellow Solid
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Storage: Store at -20°C under inert atmosphere
Density: 1.31±0.1 g/cm3
Melting Point: 95-98°C
InChIKey: KEVMXGNDTKPSMC-MUMPVVMASA-N
Solubility: Soluble in Acetonitrile (Sparingly), Chloroform (Slightly), DMF (Slightly, Sonicated), DMSO
CanonicalSMILES: COCCOC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C41H41N5O8/c1-49-22-23-52-36-35(47)33(54-40(36)46-26-44-34-37(42-25-43-38(34)46)45-39(48)27-10-6-4-7-11-27)24-53-41(28-12-8-5-9-13-28,29-14-18-31(50-2)19-15-29)30-16-20-32(51-3)21-17-30/h4-21,25-26,33,35-36,40,47H,22-24H2,1-3H3,(H,42,43,45,48)/t33-,35-,36-,40-/m1/s1
Synonyms: N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosine; N-(9-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-adenosine; 2'-O-MOE-5'-O-DMT-A(Bz); 5'-O-DMT-2'-O-MOE-N6-Bz-rA

5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine

Description: 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine, an intriguing bioactive compound, has garnered attention in the biomedical industry for its potential antiviral prowess. Demonstrating commendable efficacy in impeding viral replication, it holds promise in combatting viral ailments such as herpes and hepatitis. However, the precise workings of this compound remain enigmatic, warranting further exploration in the realm of antiviral drug development.
CAT: BRP-00106
CAS: 251647-50-4
Molecular Formula: C38H43N5O9
Molecular Weight: 713.78
Purity: ≥95%
Appearance: White to Pale Yellow Crystalline Powder
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Storage: Store at RT
Density: 1.33±0.1 g/cm3(Predicted)
Melting Point: 112.5-126.6 °C
InChIKey: XDLPRZLZAFJSMA-BEGXHNNXSA-N
Solubility: Soluble in Hexane
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OCCOC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C38H43N5O9/c1-23(2)34(45)41-37-40-33-30(35(46)42-37)39-22-43(33)36-32(50-20-19-47-3)31(44)29(52-36)21-51-38(24-9-7-6-8-10-24,25-11-15-27(48-4)16-12-25)26-13-17-28(49-5)18-14-26/h6-18,22-23,29,31-32,36,44H,19-21H2,1-5H3,(H2,40,41,42,45,46)/t29-,31-,32-,36-/m1/s1
Synonyms: N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 2'-O-MOE-5'-O-DMT-G(iBu); 5'-O-DMT-2'-O-MOE-N2-iBu-rG; 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine

2'-O-(2-Methoxyethyl)-5-methylcytidine

Description: 2'-O-(2-Methoxyethyl)-5-methylcytidine is an intrinsic antiviral compound, garnering substantial interest within the biomedical field for the research of its efficacy against RNA viruses. By impeding viral replication, this compound presenting a formidable prospect for the formulation of unprecedented antiviral interventions.
CAT: BRP-00107
CAS: 244105-55-3
Molecular Formula: C13H21N3O6
Molecular Weight: 315.32
Purity: ≥98% by HPLC
Appearance: White to off-white crystalline powder
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Storage: Store at -20°C under inert atmosphere
Density: 1.52 g/cm3
Melting Point: >70°C (dec.)
Boiling Point: 536.5±60.0 °C(Predicted)
InChIKey: GUEIFVRYWPOXHJ-DNRKLUKYSA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)
CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)OCCOC
IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidin-2-one
InChI: InChI=1S/C13H21N3O6/c1-7-5-16(13(19)15-11(7)14)12-10(21-4-3-20-2)9(18)8(6-17)22-12/h5,8-10,12,17-18H,3-4,6H2,1-2H3,(H2,14,15,19)/t8-,9-,10-,12-/m1/s1
Synonyms: 5-Me-2'-O-MOE-C; 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one; 5-Methyl-2'-O-methoxyethyl-cytidine; 5-Me-2'-O-MOE-Cr

N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine

Description: N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine, a potent biomedicine, holds significant promise as an antiviral therapeutic agent.
CAT: BRP-00108
CAS: 182496-01-1
Molecular Formula: C41H43N3O9
Molecular Weight: 721.79
Purity: ≥95%
Appearance: White to Off-white Powder
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Storage: Store at -20°C
Density: 1.26±0.1 g/cm3
InChIKey: BYSCLUAIKFEFAH-LZURGKRNSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OCCOC
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C41H43N3O9/c1-27-25-44(40(47)43-37(27)42-38(46)28-11-7-5-8-12-28)39-36(51-24-23-48-2)35(45)34(53-39)26-52-41(29-13-9-6-10-14-29,30-15-19-32(49-3)20-16-30)31-17-21-33(50-4)22-18-31/h5-22,25,34-36,39,45H,23-24,26H2,1-4H3,(H,42,43,46,47)/t34-,35-,36-,39-/m1/s1
Synonyms: N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-(2-methoxyethyl)-5-methylcytidine; N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine; N4-Benzoyl-2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine; 2'-O-MOE-5'-O-DMT-5-Me-C(Bz); 5'-O-DMT-2'-O-MOE-5-Me-C(Bz)

2'-O-(2-Methoxyethy)-5-methyluridine

Description: 2'-O-(2-Methoxyethy)-5-methyluridine is a nucleoside analog renowned in the biomedical realm, unveiling its potent antiviral attributes. I
CAT: BRP-00109
CAS: 163759-49-7
Molecular Formula: C13H20N2O7
Molecular Weight: 316.31
Purity: ≥95%
Appearance: White to Off-white Crystalline Powder
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Storage: Store at -20°C under inert atmosphere
Density: 1.41 g/cm3
Melting Point: 115.5-116.5 °C
InChIKey: NEVQCHBUJFYGQO-DNRKLUKYSA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)OCCOC
IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
InChI: InChI=1S/C13H20N2O7/c1-7-5-15(13(19)14-11(7)18)12-10(21-4-3-20-2)9(17)8(6-16)22-12/h5,8-10,12,16-17H,3-4,6H2,1-2H3,(H,14,18,19)/t8-,9-,10-,12-/m1/s1
Synonyms: 2'-O-MOE-5-Methyluridine; 2'-O-Methoxyethyl-thymidine; 2'-O-MOE-T; 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5-Me-2'-O-MOE U; 5-Me-2'-O-MOE Uridine

5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine

Description: 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a potent compound used in research of RNA viruses, particularly hepatitis C virus and picornaviruses. This nucleoside analogue inhibits viral replication by interfering with viral RNA research and development.
CAT: BRP-00110
CAS: 163759-50-0
Molecular Formula: C34H38N2O9
Molecular Weight: 618.67
Purity: ≥98% by HPLC
Appearance: Off-white Crystalline Powder
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Storage: Store at RT
Density: 1.32 g/cm3
InChIKey: WIPCVBQXKBWNRC-PBAMLIMUSA-N
CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OCCOC
IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
InChI: InChI=1S/C34H38N2O9/c1-22-20-36(33(39)35-31(22)38)32-30(43-19-18-40-2)29(37)28(45-32)21-44-34(23-8-6-5-7-9-23,24-10-14-26(41-3)15-11-24)25-12-16-27(42-4)17-13-25/h5-17,20,28-30,32,37H,18-19,21H2,1-4H3,(H,35,38,39)/t28-,29-,30-,32-/m1/s1
Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine; 5'-O-DMT-2'-O-MOE-5-methyluridine; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyluridine; 5'-O-DMT-2'-O-MOE-5-MeU

2,2'-Anhydrouridine

Description: 2,2'-Anhydrouridine is a modified nucleoside that lacks a hydroxyl group at the 2' position of the ribose ring. It is commonly found in transfer RNA (tRNA) and plays a role in stabilizing the tRNA structure. This modification is important for proper tRNA function as it helps maintain the overall stability and folding of the molecule. 2,2'-Anhydrouridine is also known to be involved in the recognition and binding of tRNA to the ribosome during protein synthesis.
CAT: BRP-00111
CAS: 3736-77-4
Molecular Formula: C9H10N2O5
Molecular Weight: 226.19
Purity: ≥95%
Appearance: White to off-white (Solid)
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Storage: Store at RT
Density: 2.01±0.1 g/cm3
Melting Point: 234-235 °C
Boiling Point: 456.3±55.0 °C at 760 mmHg
Flash Point: 229.8±31.5 °C
InChIKey: UUGITDASWNOAGG-CCXZUQQUSA-N
Solubility: Soluble in DMSO
CanonicalSMILES: C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=O
IUPAC Name: (2R,4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one
InChI: InChI=1S/C9H10N2O5/c12-3-4-6(14)7-8(15-4)11-2-1-5(13)10-9(11)16-7/h1-2,4,6-8,12,14H,3H2/t4-,6-,7+,8-/m1/s1
Synonyms: 2,2'-Anhydro-b-D-arabinofuranosyl uracil; O-2,2'-Cyclouridine; 2,2'-Anhydro-D-uridine; 2,2'-Anhydro Uridine; (2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-2-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-on; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, [2R-(2α,3β,3aβ,9aβ)]-; 2,2'-Anhydro(1-β-D-arabinofuranosyl)uracil; 2,2'-Anhydro-N1-(β-D-arabinofuranosyl)uracil; 2,2'-Anhydrouridine; 2,2'-O-Cyclouridine; NSC 157148; O2,2'-Anhydrouridine; O2,2'-Cyclouridine; β-D-2',2-O-Cycloarabinouridine

2,2'-Anhydro-5-methyluridine

Description: 2,2'-Anhydro-5-methyluridine is a chemically modified nucleoside derivative of uridine, where the 2' hydroxyl group of the ribose is linked to the 2-position of the uracil ring, forming an anhydro bond. Additionally, the uracil base is methylated at the 5-position. This modification alters the nucleoside's properties, making it useful in biochemical and pharmacological research, particularly in studies focused on nucleic acid chemistry and potential therapeutic applications.
CAT: BRP-00112
CAS: 22423-26-3
Molecular Formula: C10H12N2O5
Molecular Weight: 240.21
Purity: ≥95%
Appearance: White to off-white crystalline powder
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Storage: Store at RT
Density: 1.88±0.1 g/cm3 (Predicted)
Melting Point: 217.0-221.0 °C
Boiling Point: 452.0±55.0 °C (Predicted)
InChIKey: WLLOAUCNUMYOQI-JAGXHNFQSA-N
CanonicalSMILES: CC1=CN2C3C(C(C(O3)CO)O)OC2=NC1=O
IUPAC Name: (2R,4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one
InChI: InChI=1S/C10H12N2O5/c1-4-2-12-9-7(6(14)5(3-13)16-9)17-10(12)11-8(4)15/h2,5-7,9,13-14H,3H2,1H3/t5-,6-,7+,9-/m1/s1
Synonyms: O-2,2'-Anhydro-5-methyluridine; 2,2'-Anhydro-5-methyl-D-uridine; 2,2'-Anhydro-(1-b-D-arabinofuranosyl)-5-methyluracil; 2,2'-Anhydro-D-thymidine; 2,2'-Anhydro-5-methyluridine; (2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one; 2,2'-Anhydro-1-beta-arabinofuranosylthymine

5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine

Description: 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is an exceptionally powerful antiviral compound, possessing an unparalleled propensity to combat the scourges perpetuated by viral entities. It acts as a formidable weapon against the replication machineries employed by diverse RNA viruses, such as influenza, hepatitis C and respiratory syncytial virus (RSV).
CAT: BRP-00114
CAS: 182496-00-0
Molecular Formula: C34H39N3O8
Molecular Weight: 617.69
Purity: ≥95% by HPLC
Appearance: White to Off-white Solid
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Storage: Store at 2-8 °C
Density: 1.27±0.1 g/cm3 (Predicted)
Boiling Point: 762.6±70.0 °C at 760 mmHg
InChIKey: LYKTVJJXZQTNPK-PBAMLIMUSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OCCOC
IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidin-2-one
InChI: InChI=1S/C34H39N3O8/c1-22-20-37(33(39)36-31(22)35)32-30(43-19-18-40-2)29(38)28(45-32)21-44-34(23-8-6-5-7-9-23,24-10-14-26(41-3)15-11-24)25-12-16-27(42-4)17-13-25/h5-17,20,28-30,32,38H,18-19,21H2,1-4H3,(H2,35,36,39)/t28-,29-,30-,32-/m1/s1
Synonyms: 4-Amino-1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one; 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine; 2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine; 2'-O-MOE-5'-O-DMT-5-Me-C; 5'-O-DMT-2'-O-MOE-5-MeC

2,2'-Anhydro-5'-O-DMT-5-methyluridine

Description: 2,2'-Anhydro-5'-O-DMT-5-methyluridine is a remarkable biomedicine agent having shown substantial efficacy in research of combating viral infections and specific neoplastic conditions. Unveiling its antiviral prowess against RNA viruses, this compound showcases a promising proclivity for impeding malignant tumor expansion.
CAT: BRP-00115
CAS: 817623-11-3
Molecular Formula: C31H30N2O7
Molecular Weight: 542.58
Purity: ≥95%
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Storage: Store at 2-8 °C
Density: 1.3±0.1 g/cm3
Boiling Point: 692.9±65.0°C at 760 mmHg
InChIKey: BQEQCEZNLIKSSH-CITHKVLSSA-N
CanonicalSMILES: CC1=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OC2=NC1=O
IUPAC Name: (2R,4R,5R,6S)-4-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-hydroxy-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one
InChI: InChI=1S/C31H30N2O7/c1-19-17-33-29-27(40-30(33)32-28(19)35)26(34)25(39-29)18-38-31(20-7-5-4-6-8-20,21-9-13-23(36-2)14-10-21)22-11-15-24(37-3)16-12-22/h4-17,25-27,29,34H,18H2,1-3H3/t25-,26-,27+,29-/m1/s1
Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-5-methyl-2,2'-anhydro-b-D-arabinofuranosyluracil; 5'-O-(4,4'-Dimethoxytrityl)-5-methyl-2,2'-anhydro-D-uridine; 5'-DMTr-2,2'-anhydrothymidine; (2R,3R,3aS,9aR)-2-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-hydroxy-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one
* Only for research. Not suitable for any diagnostic or therapeutic use.
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