Nucleosides - RNA / BOC Sciences

5-Methoxycarbonylmethyluridine (BRP-02131)

Description: 5-Methoxycarbonyl methyl uridine is a nucleoside constituent of yeast transfer RNA. 5-Methoxycarbonyl methyl uridine is also a derivative of 5-carboxymethyluridine, a carboxyl-containing nucleoside that was isolated from transfer RNA of Baker's Yeast.

CAT: BRP-02131

CAS: 29428-50-0

MF: C12H16N2O8

MF: 316.26

Purity: ≥95%

Appearance: White to Off-white Solid

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100 mg	$729	In stock

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Storage: Store at -20 °C

Density: 1.570±0.06 g/cm3 at 20°C, 760 Torr

Melting Point: 160-162 °C

Symbol: mcm⁵U

InChIKey: YIZYCHKPHCPKHZ-PNHWDRBUSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: COC(=O)CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: methyl 2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]acetate

InChI: InChI=1S/C12H16N2O8/c1-21-7(16)2-5-3-14(12(20)13-10(5)19)11-9(18)8(17)6(4-15)22-11/h3,6,8-9,11,15,17-18H,2,4H2,1H3,(H,13,19,20)/t6-,8-,9-,11-/m1/s1

Synonyms: 5-(Methoxycarbonyl)methyluridine (MCM5U); Uridine 5-acetic acid methyl ester; 1,2,3,4-Tetrahydro-2,4-dioxo-1-beta-D-ribofuranosyl-5-pyrimidineacetic acid methyl ester; 5-(2-methoxy-2-oxoethyl)uridine; 5-Mcmu; Methyl 2-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetate

5-Methoxycarbonylmethyl-2'-O-methyluridine (BRP-02136)

Description: 5-Methoxycarbonylmethyl-2'-O-methyluridine, an indispensable biomedical compound, is extensively employed in the realm of research and development for antiviral drugs. This multifaceted compound assumes a paramount role in tackling diverse viral infections, meticulously targeting distinctive RNA viruses. Its eminent significance stems from its peculiar chemical structure which confers it with the potential to exhibit vigorous antiviral activity, hindering viral replication.

CAT: BRP-02136

CAS: 60197-31-1

MF: C13H18N2O8

MF: 330.29

Purity: ≥95%

Appearance: White to Off-white Solid

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5 mg	$599	In stock
20 mg	$990	In stock

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Storage: Store at 2-8 °C

Density: 1.50±0.1 g/cm3

Symbol: mcm⁵Um

InChIKey: XOTXNXXJZCFUOA-UGKPPGOTSA-N

CanonicalSMILES: COC1C(C(OC1N2C=C(C(=O)NC2=O)CC(=O)OC)CO)O

IUPAC Name: methyl 2-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]acetate

InChI: InChI=1S/C13H18N2O8/c1-21-8(17)3-6-4-15(13(20)14-11(6)19)12-10(22-2)9(18)7(5-16)23-12/h4,7,9-10,12,16,18H,3,5H2,1-2H3,(H,14,19,20)/t7-,9-,10-,12-/m1/s1

Synonyms: 5-(Methoxycarbonyl)methyl-2'-O-Methyl uridine; (2-OMe-MCM5U); 2'-O-Methyluridine 5-acetic acid methyl ester; 1,2,3,4-Tetrahydro-1-(2-O-methyl-beta-D-ribofuranosyl)-2,4-dioxo-5-pyrimidineacetic acid methyl ester; 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-1-(2-O-methyl-b-D-ribofuranosyl)-2,4-dioxo-, methyl ester; Methyl 2-(1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetate

1-Methyladenosine (BRP-02149)

Description: 1-Methyladenosine is a modified nucleoside often found in tRNAs and rRNA. In the biomedical industry, it is pivotal for protein synthesis, cellular function, and responses to stressors. It's also being studied concerning viral RNA methylation in diseases such as hepatitis C.

CAT: BRP-02149

CAS: 15763-06-1

MF: C11H15N5O4

MF: 281.27

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

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500 mg	$257	In stock

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Storage: Store at -20 °C, under inert atmosphere

Density: 1.88±0.1 g/cm3

Melting Point: >217 °C (dec.)

Boiling Point: 655.4±65.0 °C at 760 mmHg

Symbol: m¹A

InChIKey: GFYLSDSUCHVORB-IOSLPCCCSA-N

Solubility: Soluble in DMSO (Slightly), Water (Slightly, Sonicated)

CanonicalSMILES: CN1C=NC2=C(C1=N)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methylpurin-9-yl)oxolane-3,4-diol

InChI: InChI=1S/C11H15N5O4/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11-12,17-19H,2H2,1H3/t5-,7-,8-,11-/m1/s1

Synonyms: Adenosine, 1-methyl-; N1-Methyladenosine; N1-Methyl-D-adenosine; NSC 92165; (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)tetrahydrofuran-3,4-diol; Adenosine, N,6-didehydro-1,9-dihydro-1-methyl-

2'-O-Methylcytidine

Description: Cytidine analog. Used for preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.

CAT: BRP-00010

CAS: 2140-72-9

MF: C10H15N3O5

MF: 257.24

Purity: ≥95%

Appearance: White Solid

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Storage: Store at 2-8°C

Density: 1.68±0.1 g/cm3 (Predicted)

Melting Point: >247°C (dec.)

Boiling Point: 506.0±60.0°C (Predicted)

Flash Point: 259.8±32.9 °C

Symbol: Cm

InChIKey: RFCQJGFZUQFYRF-ZOQUXTDFSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated)

CanonicalSMILES: COC1C(C(OC1N2C=CC(=NC2=O)N)CO)O

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C10H15N3O5/c1-17-8-7(15)5(4-14)18-9(8)13-3-2-6(11)12-10(13)16/h2-3,5,7-9,14-15H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,9-/m1/s1

Synonyms: 2'-(O-Methyl) Cytidine; Cytidine, 2'-O-methyl-; 2'-O-Methyl cytidine; O(2')-Methylcytidine; 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 4-Amino-1-(2-O-methyl-β-D-ribofuranosyl)pyrimidin-2(1H)-one

2'-O-Methylguanosine

Description: It is a guanine nucleoside analogue that is used to prepare nucleoside derivatives as inhibitors of RNA-dependent RNA virus polymerases.

CAT: BRP-00011

CAS: 2140-71-8

MF: C11H15N5O5

MF: 297.27

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at 2-8°C

Density: 1.98±0.1 g/cm3 (Predicted)

Melting Point: >216°C (dec.)

Boiling Point: 711.7°C at 760 mmHg

Symbol: Gm

InChIKey: OVYNGSFVYRPRCG-KQYNXXCUSA-N

Solubility: Soluble in Aqueous Base (Slightly), DMSO (Slightly)

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O

IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1

Synonyms: 2'-(O-Methyl) Guanosine; Guanosine, 2'-O-methyl-; 2'-O-Methyl Guanosine; O2'-Methylguanosine; 2-amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-amino-9-(2-O-methyl-beta-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one

2'-O-Methyl-5-methylcytidine

Description: 2'-O-Methyl-5-methylcytidine is a biomedical compound unveiling powerful antiviral potential. It can effectively thwart their nefarious RNA enhancement machinery, thus abruptly halting their audacious replication endeavors.

CAT: BRP-00013

CAS: 113886-70-7

MF: C11H17N3O5

MF: 271.27

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

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Storage: Store at 2-8°C

Density: 1.61±0.1 g/cm3(Predicted)

Melting Point: 235-238°C

Boiling Point: 504.6±60.0 °C(Predicted)

Symbol: m⁵Cm

InChIKey: CNVRVGAACYEOQI-FDDDBJFASA-N

Solubility: Soluble in DMSO (Slightly), Water (Slightly, Sonicated)

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)OC

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-5-methylpyrimidin-2-one

InChI: InChI=1S/C11H17N3O5/c1-5-3-14(11(17)13-9(5)12)10-8(18-2)7(16)6(4-15)19-10/h3,6-8,10,15-16H,4H2,1-2H3,(H2,12,13,17)/t6-,7-,8-,10-/m1/s1

Synonyms: 2'-(O-Methyl)-5-Methyl Cytidine; 5,2'-O-dimethylcytidine; Cytidine, 5-methyl-2'-O-methyl-; 5-methyl-2'-O-methylcytidine; 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one

5-Iodotubercidin

Description: It is an adenosine kinase inhibitor, protein kinase inhibitor and activator, nucleoside transporter inhibitor.

CAT: BRP-00017

CAS: 24386-93-4

MF: C11H13IN4O4

MF: 392.15

Purity: ≥95%

Appearance: Off-white to Light Brown Solid

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Storage: Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -113°C for long term (months to years).

Density: 2.49 g/cm3

Melting Point: 216-217°C (dec.)

Boiling Point: 701.5±60.0 °C | Condition: Press: 760 Torr

Application: An analogue of the antibiotic tubercidin, a pyrrolo[2,3-d]pyrimidine nucleoside antibiotic. A potent inhibitor of adenosine kinase from rat or guinea pig brain. Inhibits uptake of 3H-adenosine into brain slices.

Shelf Life: 2 years

InChIKey: WHSIXKUPQCKWBY-IOSLPCCCSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated)

CanonicalSMILES: C1=C(C2=C(N1C3C(C(C(O3)CO)O)O)N=CN=C2N)I

IUPAC Name: (2R,3R,4S,5R)-2-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C11H13IN4O4/c12-4-1-16(10-6(4)9(13)14-3-15-10)11-8(19)7(18)5(2-17)20-11/h1,3,5,7-8,11,17-19H,2H2,(H2,13,14,15)/t5-,7-,8-,11-/m1/s1

Synonyms: 7-Iodo-tubercidin; 7-Deaza-7-iodoadenosine; 4-Amino-5-iodo-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine; NSC 113939; 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 7-iodo-7-deazaadenosine; 7-deaza-7-I-Ar

5-Iodocytidine

Description: 5-Iodocytidine is an intermediate for research in the field of nucleic acids and nucleic acid-protein interactions.

CAT: BRP-00019

CAS: 1147-23-5

MF: C9H12IN3O5

MF: 369.11

Purity: ≥95%

Appearance: White solid

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Storage: Store at -20 °C

Density: 2.52±0.1 g/cm³ (Predicted)

Melting Point: >160 °C (dec.)

Boiling Point: 565.5±60.0 °C at 760 mmHg

InChIKey: LQQGJDJXUSAEMZ-UAKXSSHOSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=C(C(=NC(=O)N1C2C(C(C(O2)CO)O)O)N)I

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one

InChI: InChI=1S/C9H12IN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1

Synonyms: 1-β-D-Ribofuranosyl-5-iodocytosine; 5-Iodo-cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; 5-Iodo-ribo Cytidine

5-Iodouridine

Description: It is a Rho-GTPase cell protein inhibitor.

CAT: BRP-00020

CAS: 1024-99-3

MF: C9H11IN2O6

MF: 370.10

Purity: ≥95%

Appearance: White Powder

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Storage: Store at 2-8°C

Density: 2.27±0.1 g/cm3 (Predicted)

Melting Point: 205-207°C (dec.)

InChIKey: RKSLVDIXBGWPIS-UAKXSSHOSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)I

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione

InChI: InChI=1S/C9H11IN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1

Synonyms: NSC 523375; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 2,4-Dihydroxy-5-iodo-1-β-D-ribofuranosylpyrimidine; 5-Iodo-1-(β-D-ribofuranosyl)uracil; 5-Iodo Uridine

Adenosine

Description: Adenosine is a purine nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.

CAT: BRP-00021

CAS: 58-61-7

MF: C10H13N5O4

MF: 267.24

Purity: ≥95% by HPLC

Appearance: white crystalline powder

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Storage: Store at 2-8°C

Density: 2.08 g/cm3

Melting Point: 234-236°C

Boiling Point: 676.3°C at 760 mmHg

Application: neuromodulator

InChIKey: OIRDTQYFTABQOQ-KQYNXXCUSA-N

Solubility: Soluble in water

CanonicalSMILES: C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1

Synonyms: Adenocard; Adenoscan; Adenine riboside; ribo Adenosine; rA; 9-β-D-Ribofuranosyl-9H-purin-6-amine; 9-β-D-Ribofuranosyladenine; D-Adenosine; Boniton; Myocol; NQZ-012; NSC 7652; Nucleocardyl; Riboadenosine; Sandesin; β-D-Adenosine; β-D-Ribofuranoside, adenine-9; β-Adenosine

Uridine

Description: Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.

CAT: BRP-00038

CAS: 58-96-8

MF: C9H12N2O6

MF: 244.20

Purity: ≥98% by HPLC

Appearance: white crystalline powder

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Storage: Store at 2-8°C

Density: 1.674±0.06 g/cm3

Melting Point: 165 °C

Boiling Point: 387.12°C (rough estimate)

InChIKey: DRTQHJPVMGBUCF-XVFCMESISA-N

Solubility: Soluble in water (50 mg/mL), dimethylsulfoxide, methanol

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

Synonyms: 1-beta-D-Ribofuranosyluracil; NSC 20256; NSC-20256; NSC20256; Uracil riboside; Uracil, 1-β-D-ribofuranosyl-; 1-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione; 1-β-D-Ribofuranosyluracil; Uridin; β-D-Ribofuranoside, 2,4(1H,3H)-pyrimidinedione-1; β-Uridine

N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine

Description: N2-iso-Butyroyl-2'-O-(2-methoxyethyl)guanosine, a remarkable biomedical compound renowned for its exceptional antiviral attributes, is indeed a profound breakthrough in the field. With its unrivaled inhibitory prowess against viral replication, this marvel exhibits immense promise in combatting treacherous RNA viruses, namely hepatitis C and dengue fever. Its captivating mode of operation revolves around perturbing viral RNA synthesis, thereby positioning itself as an invaluable contender within the realm of antiviral therapeutics.

CAT: BRP-00055

CAS: 440327-50-4

MF: C17H25N5O7

MF: 411.41

Purity: ≥95%

Appearance: White, off-white to faint yellow powder

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Storage: Store at -20°C

Shelf Life: 2 years

InChIKey: IZOOGJIUOCHAAY-UBEDBUPSSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)OCCOC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C17H25N5O7/c1-8(2)14(25)20-17-19-13-10(15(26)21-17)18-7-22(13)16-12(28-5-4-27-3)11(24)9(6-23)29-16/h7-9,11-12,16,23-24H,4-6H2,1-3H3,(H2,19,20,21,25,26)/t9-,11-,12-,16-/m1/s1

Synonyms: N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; Guanosine, 2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-; 2'-O-MOE-N2-ibu-rG; N2-isobutyryl-2-O-(2-methoxyethyl)guanosine; N2-iBu-2'-O-MOE-G; N2-isobutyryl-2'-O-methoxyethyl-guanosine

4'-alpha-Azidouridine

Description: 4'-alpha-Azidouridine, a biomedical compound, assumes paramount significance in the realm of antiviral therapy. Its applications predominantly revolve around combating viral infections instigated by RNA viruses. By selectively and adeptly impeding viral replication and transcription, this compound emerges as an efficacious weapon against afflictions like influenza, hepatitis C, and HIV.

CAT: BRP-00056

CAS: 139442-01-6

MF: C9H11N5O6

MF: 285.21

Purity: ≥95%

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InChIKey: FHPJZSIIXUQGQE-JVZYCSMKSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H11N5O6/c10-13-12-9(3-15)6(18)5(17)7(20-9)14-2-1-4(16)11-8(14)19/h1-2,5-7,15,17-18H,3H2,(H,11,16,19)/t5-,6+,7-,9-/m1/s1

Synonyms: 1-(4'-Azido-beta-D-ribofuranosyl)uracil; 4'-azidouridine; Uridine, 4-C-azido-; 1-[(2R,3R,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione; 4'-C-azidouridine

2'-C-Methyladenosine

Description: 2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication (IC50 = 0.3 µM in Huh-7 human hepatoma cells) that is not cytotoxic at concentrations up to 100 µM.

CAT: BRP-00057

CAS: 15397-12-3

MF: C11H15N5O4

MF: 281.27

Purity: ≥95%

Appearance: Solid

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Storage: 4°C, protect from light
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Density: 1.89±0.1 g/cm3

Boiling Point: 643.4±65.0 °C at 760 mmHg

InChIKey: PASOFFRBGIVJET-YRKGHMEHSA-N

Solubility: Soluble in DMF, DMSO, PBS

CanonicalSMILES: OC[C@@H]1[C@@H](O)[C@@](C)(O)[C@H](N2C3=NC=NC(N)=C3N=C2)O1

IUPAC Name: (2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol

InChI: InChI=1S/C11H15N5O4/c1-11(19)7(18)5(2-17)20-10(11)16-4-15-6-8(12)13-3-14-9(6)16/h3-5,7,10,17-19H,2H2,1H3,(H2,12,13,14)/t5-,7-,10-,11-/m1/s1

Synonyms: 2-CMA; (2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol; 6-Amino-9-(2'-C-methyl-b-D-ribofuranosyl)purine

2-C-methyl-6-O-methyl-guanosine

Description: 2-C-methyl-6-O-methyl-guanosine - an exalted nucleoside analog flourishing in the realm of biomedical applications. As a prodigious antiviral agent, its dominion extends to combating the perils inflicted by RNA viruses like hepatitis C and respiratory syncytial virus (RSV). Proficiently curbing viral replication and subduing the viral life cycle, it has garnered reverence among scientific circles. Moreover, its boundless panorama of therapeutic possibilities in countering diverse viral afflictions continues to enthrall researchers worldwide. Beware, for this extraordinary entity is unrivaled in its prowess.

CAT: BRP-00058

CAS: 714249-80-6

MF: C12H17N5O5

MF: 311.29

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Density: 1.8±0.1 g/cm3

Boiling Point: 690.2±65.0 °C(Predicted)

InChIKey: OAIGYKVLSKBAJZ-GSWPYSDESA-N

CanonicalSMILES: CC1(C(C(OC1N2C=NC3=C2N=C(N=C3OC)N)CO)O)O

IUPAC Name: (2R,3R,4R,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)-3-methyloxolane-3,4-diol

InChI: InChI=1S/C12H17N5O5/c1-12(20)7(19)5(3-18)22-10(12)17-4-14-6-8(17)15-11(13)16-9(6)21-2/h4-5,7,10,18-20H,3H2,1-2H3,(H2,13,15,16)/t5-,7-,10-,12-/m1/s1

Synonyms: (2R,3R,4R,5R)-2-(2-Amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyltetrahydrofuran-3,4-diol; 2'-C-Methyl-6-O-methyl-guanosine; INX 08144

2'-C-Methylcytidine

Description: A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication.

CAT: BRP-00059

CAS: 20724-73-6

MF: C10H15N3O5

MF: 257.24

Purity: ≥95%

Appearance: white to off-white powder

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Storage: Store in a cool and dry place and at 2-8 °C for short term (days to weeks) or -20 °C for long term (months to years)

Density: 1.72±0.10 g/cm3

Melting Point: 243-245 °C

Boiling Point: 523.9±60.0 °C at 760 mmHg

Flash Point: 270.7±32.9 °C

Shelf Life: 2 years

InChIKey: PPUDLEUZKVJXSZ-VPCXQMTMSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: CC1(C(C(OC1N2C=CC(=NC2=O)N)CO)O)O

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C10H15N3O5/c1-10(17)7(15)5(4-14)18-8(10)13-3-2-6(11)12-9(13)16/h2-3,5,7-8,14-15,17H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,10-/m1/s1

Synonyms: 1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-4-aminopyrimidin-2(1H)-one; 2'-C-methyl-cytidine; valopicitabine; Cytidine, 2'-C-methyl-; (+)-2'-C-Methylcytidine; NM 107

Related CAS: 115494-60-5

2'-C-beta-Methylguanosine

Description: 2'-C-β-Methyl Guanosine is an anti-HCV agent. 2'-C-β-Methyl Guanosine is an intermediate in the synthesis of novel double prodrug INX-08189, a new clinical candidate for hepatitis C virus.

CAT: BRP-00060

CAS: 374750-30-8

MF: C11H15N5O5

MF: 297.27

Purity: ≥95%

Appearance: White to Beige Powder

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Storage: Store at -20°C

Density: 2.03 g/cm3

Boiling Point: 733.1±70.0°C (Predicted)

Application: A nucleoside derivative as antiviral, antitumor, and antidiabetic prodrug agents.

InChIKey: NVKAMPJSWMHVDK-GITKWUPZSA-N

Solubility: Soluble in Water

CanonicalSMILES: CC1(C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O)O

IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C11H15N5O5/c1-11(20)6(18)4(2-17)21-9(11)16-3-13-5-7(16)14-10(12)15-8(5)19/h3-4,6,9,17-18,20H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,9-,11-/m1/s1

Synonyms: 2'-C-Methylguanosine; 2'-C-β-Methyl Guanosine; 2-Amino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-(2-C-methyl-beta-D-ribofuranosyl)-; INX 08032; INZ 08032

2'-C-Methyluridine

Description: 2'-C-Methyluridine is a 2'-C-Me branched C-nucleoside that shows HCV polymerase inhibitory activity.

CAT: BRP-00061

CAS: 31448-54-1

MF: C10H14N2O6

MF: 258.23

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at 2-8°C

Density: 1.57 g/cm3

Melting Point: 110-112 °C

InChIKey: NBKORJKMMVZAOZ-VPCXQMTMSA-N

CanonicalSMILES: CC1(C(C(OC1N2C=CC(=O)NC2=O)CO)O)O

IUPAC Name: 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C10H14N2O6/c1-10(17)7(15)5(4-13)18-8(10)12-3-2-6(14)11-9(12)16/h2-3,5,7-8,13,15,17H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,10-/m1/s1

Synonyms: 2'-C-Methyl-1-β-D-ribofuranosyluracil; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Methyl Uridine; 1,3-bis(N-cyclohexyl)guanidine; 1-(2-C-Methyl-β-D-ribofuranosyl)uracil; 2,4(1H,3H)-pyrimidinedione, 1-(2-C-methyl-β-D-ribofuranosyl)-

N6-Cyclopentyl-adenosine

Description: N6-Cyclopentyl-adenosine (CPA) - an adenosine analog and A1 adenosine receptor agonist - is pivotal in biomedicine as a research tool to inspect the part played by the adenosine receptor in distinct physiological processes. It also has potential therapeutic benefits that range from treating ischemia-reperfusion injuries to chronic pain.

CAT: BRP-00062

CAS: 41552-82-3

MF: C15H21N5O4

MF: 335.36

Purity: ≥95% by HPLC

Appearance: White to off-white solid

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Storage: Store at 2-8 °C

Density: 1.78±0.1 g/cm3 (Predicted)

Melting Point: 78.8 °C

Boiling Point: 673.4±65.0 °C at 760 mmHg

Application: Purinergic P1 Receptor Agonists

InChIKey: SQMWSBKSHWARHU-SDBHATRESA-N

Solubility: Soluble in Water

CanonicalSMILES: C1CCC(C1)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O

IUPAC Name: (2R,3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1

Synonyms: N6-Cyclopentyladenosine; CPA; N-Cyclopentyladenosine; UK 80882; (2R,3R,4S,5R)-2-[6-(Cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

EIDD-2749

Description: 4'-Fluorouridine is an orally active RdRp inhibitor. It effectively blocks the replication of RSV and SARS-CoV-2.

CAT: BRP-00063

CAS: 1613589-24-4

MF: C9H11FN2O6

MF: 262.19

Purity: 98%

Appearance: Solid

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Density: 1.77±0.1 g/cm3

InChIKey: RDCYLPRXPILMRP-JVZYCSMKSA-N

CanonicalSMILES: O=C1NC(N([C@@H]2O[C@@](CO)(F)[C@@H](O)[C@H]2O)C=C1)=O

IUPAC Name: 1-[(2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H11FN2O6/c10-9(3-13)6(16)5(15)7(18-9)12-2-1-4(14)11-8(12)17/h1-2,5-7,13,15-16H,3H2,(H,11,14,17)/t5-,6+,7-,9-/m1/s1

Synonyms: 4'-FlU; 4'-Fluorouridine