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N1-Methylpseudouridine 5'-triphosphate, tris salt

Catalog number: BRP-00466

N1-Methylpseudouridine 5'-triphosphate, tris salt

N1-Methylpseudouridine 5'-triphosphate, tris salt is a modified nucleotide used in molecular biology research. Present in tris salt form, it's readily soluble in water. This compound is commonly employed as a substrate in enzymatic reactions such as transcription and reverse transcription. Its incorporation into RNA can introduce specific methylated pseudouridine modifications, impacting RNA structure and function. These modifications are significant in mRNA stability, translation regulation, and RNA-protein interactions. In research, it facilitates the study of RNA modification dynamics and their roles in gene expression and cellular processes.

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Catalog
BRP-00466
Synonyms
HiPure® N1-Me-pUTP 100mM Tris solution GMP grade; N1-Me-pUTP, Tris Salt; 1-Methylpseudouridine-5'-Triphosphate Tris salt; N1-Methylpseudo-UTP Tris salt; 1-Methylpseudo-UTP Tris salt; N1-Methyl Pseudo UTP Tris salt; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1-methyl-2,4(1H,3H)-pyrimidinedione Tris salt; 1-N-Methyl-pseudo-UTP Tris salt; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1-methyl-, compd. with tromethamine
IUPAC Name
[[(2R,3S,4R,5S)-3,4-dihydroxy-5-(1-methyl-2,4-dioxopyrimidin-5-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate;2-amino-2-(hydroxymethyl)propane-1,3-diol
Molecular Weight
498.17 (free acid)
Molecular Formula
C10H17N2O15P3 (free acid)
Purity
≥97% by HPLC
Appearance
Clear colorless to yellow Liquid
Storage
Store at -20 °C
Related CAS
1428903-59-6 (free acid)

Chemical Structure:

Chemical structure of BRP-00466


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