Name: N1-MethylpseudoUridine-5'-Triphosphate
Brand: BOC Sciences
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N1-MethylpseudoUridine-5'-Triphosphate

N1-MethylpseudoUridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The sodium form N1-MethylpseudoUridine-5'-Triphosphate Sodium (B2706-358101) is in stock.

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Catalog

BRP-00008

Synonyms

m1Ψ; 1-Methylpseudouridine-5'-Triphosphate; N1-Methylpseudo-UTP; 1-Methylpseudo-UTP; N1-Methyl Pseudo UTP; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-1-methyl-2,4(1H,3H)-pyrimidinedione; 1-N-Methyl-pseudo-UTP

CAS

1428903-59-6

IUPAC Name

[[(2R,3S,4R,5S)-3,4-dihydroxy-5-(1-methyl-2,4-dioxopyrimidin-5-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

Molecular Weight

498.17

Molecular Formula

C10H17N2O15P3

Canonical SMILES

CN1C=C(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

InChI

InChI=1S/C10H17N2O15P3/c1-12-2-4(9(15)11-10(12)16)8-7(14)6(13)5(25-8)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5-8,13-14H,3H2,1H3,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t5-,6-,7-,8+/m1/s1

InChIKey

OLRONOIBERDKRE-XUTVFYLZSA-N

Purity

≥95%

Density

2.010±0.06 g/cm3 (Predicted)

Appearance

Clear colourless solution

Storage

Storage at -20°C

Related CAS

1931922-77-8 (tetrasodium salt) 3056945-59-3 (trisodium salt)