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LNA-ATP sodium salt

Catalog number: BRP-00652

LNA-ATP sodium salt

LNA-ATP sodium salt is a modified form of adenosine triphosphate (ATP) where a locked nucleic acid (LNA) modification is incorporated into the ribose sugar moiety. This modification increases the stability and binding affinity of ATP to complementary RNA or DNA targets. The sodium salt form enhances the solubility and stability of LNA-ATP in aqueous solutions, making it suitable for various molecular biology applications, including RNA interference (RNAi), antisense oligonucleotide therapeutics, and RNA-based diagnostics.

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Catalog
BRP-00652
Synonyms
9-[2,5-Anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-9H-purin-6-amine sodium salt; 2'-O-4'-C-Locked-ATP, sodium salt; 2'-O-4'-C-Locked-adenosine-5'-triphosphate sodium salt
IUPAC Name
sodium;((1R,3R,4R,7S)-3-(6-amino-9H-purin-9-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl tetrahydrogen triphosphate
Molecular Weight
519.19 (free acid)
Molecular Formula
C11H16N5O13P3 (free acid)
Purity
≥98%
Appearance
Clear to slightly yellow liquid
Storage
Store at -20 °C, Always avoid freeze-thaw cycles
Related CAS
2763213-05-2 (tetrasodium salt) 941597-09-7 (free acid)

Chemical Structure:

Chemical structure of BRP-00652


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