Name: LNA-ATP
Brand: BOC Sciences
Rating: 5 (1 reviews)

LNA-ATP

LNA-ATP, or Locked Nucleic Acid-adenosine triphosphate, is a modified nucleotide used in biochemical and molecular biology research. It contains an adenosine base modified with a locked nucleic acid (LNA) backbone and linked to a triphosphate group. This modified nucleotide is utilized in studies related to RNA and DNA research, where LNA modifications enhance the stability and specificity of oligonucleotides. LNA-ATP can be incorporated into RNA or DNA strands during synthesis, allowing researchers to investigate various aspects of nucleic acid structure, function, and interactions.

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Catalog

BRP-00926

Synonyms

9H-Purin-6-amine, 9-[2,5-anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-; 9-[2,5-Anhydro-4-C-(3,5,7,7-tetrahydroxy-3,5,7-trioxido-2,4,6-trioxa-3,5,7-triphosphahept-1-yl)-α-L-lyxofuranosyl]-9H-purin-6-amine; ((1R,3R,4R,7S)-3-(6-amino-9H-purin-9-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl tetrahydrogen triphosphate; LNA-A-TP

CAS

941597-09-7

IUPAC Name

[[(1R,3R,4R,7S)-3-(6-aminopurin-9-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

Molecular Weight

519.19

Molecular Formula

C11H16N5O13P3

SMILES

C1C2(C(C(O1)C(O2)N3C=NC4=C(N=CN=C43)N)O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O

InChI

InChI=1S/C11H16N5O13P3/c12-8-5-9(14-3-13-8)16(4-15-5)10-6-7(17)11(27-10,1-25-6)2-26-31(21,22)29-32(23,24)28-30(18,19)20/h3-4,6-7,10,17H,1-2H2,(H,21,22)(H,23,24)(H2,12,13,14)(H2,18,19,20)/t6-,7+,10-,11-/m1/s1

InChIKey

IYXWSFFOIIMVHP-LRMGWDNHSA-N

Boiling Point

938.3±75.0 °C at 760 mmHg

Purity

95%

Density

2.66±0.1 g/cm3

Solubility

Soluble in Water

Appearance

Lyophilized white powder