GTP-αS TEA salt

GTP-αS TEA salt is a modified form of guanosine triphosphate (GTP) where the oxygen atom in the α-phosphate group is replaced by a sulfur atom, making it a non-hydrolyzable analog of GTP. This modification allows GTP-αS to mimic the structure of GTP while preventing its hydrolysis. The TEA salt formulation enhances the solubility and stability of GTP-αS in aqueous solutions. GTP-αS TEA salt is commonly used in biochemical and molecular biology research to study GTP-dependent processes, such as signal transduction, GTPase activity, and protein synthesis.

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Catalog

BRP-00447

Synonyms

Guanosine, 5'→P''-ester with thiotriphosphoric acid TEA salt; GTPαS TEA salt; Guanosine-5'-Rp-Alpha-Thio-Triphosphate TEA salt; Guanosine 5'-O-(1-thiotriphosphate) TEA salt; Guanosine 5'-O-thiotriphosphate TEA salt

IUPAC Name

[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl] phosphono hydrogen phosphate;N,N-diethylethanamine

Molecular Weight

539.25 (free acid)

Molecular Formula

C10H16N5O13P3S (free acid)

Purity

≥95% by HPLC

Storage

Store at -20 °C

Related CAS

71376-96-0 (free base)

Chemical Structure:

Chemical structure of BRP-00447