CAS 2646703-64-0 Zerlasiran - RNA / BOC Sciences

Zerlasiran

Zerlasiran, an apolipoprotein A (ApoA) synthesis reducer, is a small interfering RNA (siRNA) therapeutic developed for the treatment of cardiovascular diseases. By specifically targeting and silencing the messenger RNA (mRNA) responsible for the production of atherogenic proteins, zerlasiran aims to reduce the expression of these proteins and thereby mitigate the progression of atherosclerosis and other related conditions.

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Catalog

BRP-02072

Synonyms

RNA, (Am-sp-(2'-deoxy-2'-fluoro)U-sp-Am-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-Cm-sp-(2'-deoxy-2'-fluoro)C-sp-Gm), complex with RNA (Cm-Gm-Gm-Um-Am-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)G-Am-Cm-Am-Gm-Am-Gm-Um-Um-sp-Am-sp-Um) 5'-[O-[21-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-9,9-bis[12-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-7-mercapto-7-oxido-2,6,8-trioxa-7-phosphadodec-1-yl]-16-mercapto-16-oxido-7,11,15,17-tetraoxa-16-phosphaheneicos-1-yl] hydroxy phosphate] (1:1)

CAS

2646703-64-0

Molecular Weight

14155.81

Molecular Formula

C443H594N144O277P40S10

Zerlasiran - CAS 2646703-64-0

Zerlasiran